Noise-augmented Automatic Speech Recognition for Speech Treatment in Parkinson's Disease
NCT06540989
Recruiting
The goal of this clinical trial is to learn whether noise-augmented feedback using automatic speech recognition improves intelligibility and social participation in individuals with Parkinson's disease. The main questions the investigators will address are: Does noise-augmented feedback lead to increased intelligibility, as measured by transcription accuracy scores? Does a self-managed speech protocol lead to increased social participation, as measured by the Communicative Participation Item B... Read More
Gender:
ALL
Ages:
Between 50 years and 80 years
Trial Updated:
08/13/2024
Locations: Teachers College, Columbia University, New York, New York
Conditions: Parkinson Disease
Register for Updates
Pilot Trial Investigating Every Other Day Dosing of Oral Iron in Premature Infants (IQONic)
NCT06555315
Recruiting
Study focuses on determining if daily versus every-other-day (EOD) oral iron at the same dose per kilogram per day will achieve similar incidence of iron replete status at 36 weeks post-menstrual age in premature neonates
Gender:
ALL
Ages:
Between 26 weeks and 32 weeks
Trial Updated:
08/13/2024
Locations: CHRISTUS Children's, San Antonio, Texas
Conditions: Very Low Birth Weight Infant, Premature Infants, Anemia of Prematurity, Iron Deficiency, Anaemia in Children, Extremely Low Birth Weight
Register for Updates
Collaborative Care for Treatment of Depression and Anxiety
NCT06556589
Recruiting
The goal of this project is to evaluate the effectiveness of a collaborative care model for primary care patients at Kaiser Permanente Colorado (KPCO) with depression and/or anxiety. Collaborative care uses evidence-based short-term treatments delivered to patients over the phone. We will explore the use of cost-efficient automated processes for patient outreach and follow-up, such as care pools of patients and using patient portal messaging, risk-based results routing to providers, and electron... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/13/2024
Locations: Kaiser Permanente Colorado, Aurora, Colorado
Conditions: Depression, Anxiety
Register for Updates
The Effects of Daily Polyvagal Exercises on Stress in Students of Physical Therapy
NCT06557083
Recruiting
The purpose of this study is to investigate whether specific breathing exercises can stimulate the polyvagal system and thus decrease stress in healthy students of physical therapy. The hypothesis is that practicing daily polyvagal breathing exercises will result in decreased stress/anxiety in physical therapy students compared to the control group who will not be receiving any intervention.
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
08/13/2024
Locations: Dominican University New York, Orangeburg, New York
Conditions: Stress, Anxiety
Register for Updates
Pilot Study on In-vivo Non-invasive Skin Imaging Using Multiphoton Microscopy
NCT01771718
Recruiting
The purpose of this pilot study is to employ multiphoton microscopy to non-invasively image in-vivo pigmented and non-pigmented human skin lesions for characterization of their morphologic and functional features. .
Gender:
ALL
Ages:
All
Trial Updated:
08/12/2024
Locations: Beckman Laser Institute Medical Clinic, Irvine, California
Conditions: Skin Lesion
Register for Updates
Evaluation of the PACE/PACENET BHL Clinical Program
NCT02463266
Recruiting
The SUpporting Seniors Receiving Treatment And INtervention (SUSTAIN) program is a telephone-based clinical service designed to help identify and manage behavioral health issues among PACE/PACENET enrollees. The purpose of the current project is to a) explore moderators of treatment response among beneficiaries in the SUSTAIN Clinical Program and b) to evaluate the sustained clinical effects of the program.
Gender:
ALL
Ages:
65 years and above
Trial Updated:
08/12/2024
Locations: Department of Psychiatry (Center for Psychotherapy Research), University of Pennsylvania, Philadelphia, Pennsylvania
Conditions: Depression, Anxiety, Pain, Chronic
Register for Updates
Sleep Disturbance and Emotion Regulation Brain Dysfunction as Mechanisms of Neuropsychiatric Symptoms in Alzheimer's Dementia
NCT04100057
Recruiting
Recent findings suggest that sleep disruption may contribute to the generation and maintenance of neuropsychiatric symptoms including anxiety, depression, agitation, irritation, and apathy while treating sleep disruption reduces these symptoms. Impairments in the neural systems that support emotion regulation may represent one causal mechanism mediating the relationship between sleep and emotional distress. However, this model has not yet been formally tested within a sample of individuals with... Read More
Gender:
ALL
Ages:
Between 50 years and 90 years
Trial Updated:
08/12/2024
Locations: Andrea Goldstein-Piekarski, PhD, Palo Alto, California
Conditions: Alzheimer Disease, Mild Cognitive Impairment, Neuropsychiatric Symptoms, Sleep Disturbance
Register for Updates
Rapamycin - Effects on Alzheimer's and Cognitive Health
NCT04629495
Recruiting
This study will evaluate the safety, tolerability, and feasibility of 12 month oral rapamycin treatment in older adults with amnestic mild cognitive impairment (aMCI) and early stage Alzheimer's disease (AD).
Gender:
ALL
Ages:
Between 55 years and 89 years
Trial Updated:
08/12/2024
Locations: Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, San Antonio, Texas
Conditions: Mild Cognitive Impairment, Alzheimer Disease
Register for Updates
ROX Index for the Timing of Intubation in Nasal High Flow
NCT04707729
Recruiting
Late or delayed intubation in patients with acute hypoxemic respiratory failure (AHRF) treated with nasal high flow (NHF) is associated with increased patient mortality. The ROX index has been designed and validated to predict outcome of NFH therapy by identifying those patients with a high risk of NHF failure and those with a high probability of success. Whether or not the ROX index may improve patient outcome remains to be shown. To do so, a strategy using the ROX index must lead to earlier in... Read More
Gender:
ALL
Ages:
Between 18 years and 120 years
Trial Updated:
08/12/2024
Locations: Rush University Chicago Hospital, Chicago, Illinois +11 locations
Conditions: Acute Hypoxemic Respiratory Failure
Register for Updates
Comparing Brief Behavioral Therapy (BBT-CI) and Healthy Eating Education Learning (HEAL) for Cancer-Related Sleep Problems While Receiving Chemotherapy
NCT04829539
Recruiting
This phase III trial compares BBT-CI to HEAL for the reduction of insomnia in patients with stage I-IV cancer who are receiving cancer treatment. Cancer treatment can cause side effects such as sleep problems. Sleep problems such as insomnia, are common for cancer patients. Insomnia can be described as difficulty falling asleep, waking up many times during the night or waking up earlier than patient would like. Insomnia can increase fatigue and worsen quality of life. This trial may help researc... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/12/2024
Locations: Kingman Regional Medical Center, Kingman, Arizona +129 locations
Conditions: Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Register for Updates
Individualized Vocational and Educational Support and Training for Clinical High Risk for Psychosis (InVEST)
NCT05114733
Recruiting
The purpose of this study is to test the efficacy of InVEST (Individualized Vocational and Educational Support and Training) for CHR-P (clinical high risk for psychosis) to address specific role functioning difficulties associated with the CHR-P phase. Our specific goals are: 1. Part 1: Preliminary open trial of InVEST (n = 8) to collect preliminary feasibility and acceptability data by providing the intervention, administering assessments, and collecting focus group and self-report feedback fr... Read More
Gender:
ALL
Ages:
Between 12 years and 22 years
Trial Updated:
08/12/2024
Locations: Beth Israel Deaconess Medical Center/ Massachusetts Mental Health Center, Boston, Massachusetts
Conditions: Clinical High Risk for Psychosis
Register for Updates
Ketone Ester and Acute Salt (KEAS) in Young Adults
NCT05545501
Recruiting
Most Americans consume excess dietary salt based on the recommendations set by the American Heart Association and Dietary Guidelines for Americans. High dietary salt impairs the ability of systemic blood vessels and the kidneys to control blood pressure, which contributes to excess salt consumption being associated with increased risk for chronic kidney disease and cardiovascular disease, the leading cause of death in America. There is a critical need for strategies to counteract the effects of... Read More
Gender:
ALL
Ages:
Between 18 years and 39 years
Trial Updated:
08/12/2024
Locations: Auburn University, Auburn, Alabama
Conditions: Salt; Excess, Hypertension
Register for Updates