Neural Enabled Prosthesis for Upper Limb Amputees
Recruiting
This study is designed to evaluate the feasibility of The Adaptive Neural Systems Neural-Enabled Prosthetic Hand (ANS-NEPH) system.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/13/2024
Locations: University of Arkansas, Fayetteville, Arkansas +1 locations
Conditions: Amputation Arm and Hand, Unilateral Right, Amputation Arm and Hand, Unilateral Left, Prosthesis User
University of Delaware Parkinson's Disease Registry
Recruiting
The purpose of this Parkinson's Disease Registry is to assist with recruitment of willing participants into future Parkinson's disease research studies at the University of Delaware.
Gender:
ALL
Ages:
Between 21 years and 100 years
Trial Updated:
05/13/2024
Locations: University of Delaware, Newark, Delaware
Conditions: Parkinson Disease
Targeting Processing Speed Deficits to Improve Social Functioning and Lower Psychosis Risk
Recruiting
This 10 week intervention, Specific Cognitive Remediation with Surround (or SCORES), is designed to target processing speed, a cognitive domain related directly to social functioning, which in turn, represents a vulnerability factor for psychosis. This remotely-delivered intervention combining targeted cognitive training exercises and group support was developed to directly impact processing speed, and at the same time, boost motivation and engagement in adolescents at risk for schizophrenia and... Read More
Gender:
ALL
Ages:
Between 14 years and 20 years
Trial Updated:
05/13/2024
Locations: Northwell Health- The Zucker Hillside Hospital, Glen Oaks, New York
Conditions: Psychosis, Prodromal Schizophrenia, Prodromal Symptoms
Conventional vs Bipolar SIJ RFA for Treatment of Sacroiliac Joint Pain
Recruiting
Specific Aims The sacroiliac joint complex (SIJC) is a diathrodial, synovial joint and posterior ligamentous network that receives both anterior innervation from the lumbosacral plexus as well as posterior sensory innervation via the posterior sacral network (PSN). The PSN is comprised by the lateral branches S1-S3 posterior rami, with variable contributions from S4 lateral branch, L4 medial branch, and L5 dorsal ramus. Pain signals originating from the SIJC can be interrupted with image-guided... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
05/13/2024
Locations: University of Utah Farmington Health Center, Farmington, Utah +2 locations
Conditions: Sacroiliac Joint Complex, Low Back Pain
Transpulmonary Pressure Guided Mechanical Ventilation Weaning in Obesity
Recruiting
This study will look at whether accounting for the amount of pressure generated by the chest wall and abdomen in a obese patient, using a measurement called transpulmonary pressure, can help shorten the amount of time patients spend on the ventilator. By decreasing the amount of time patients spend on the ventilator, they are less likely to develop complications such as infections, weakness or more procedures.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/13/2024
Locations: University of Mississippi Medical Center, Jackson, Mississippi
Conditions: Respiratory Failure, Obesity
A Study to Learn About Variant-Adapted COVID-19 RNA Vaccine Candidate(s) in Healthy Children
Recruiting
The purpose of this clinical trial is to learn about the safety, extent of the side effects, and immune responses of the study vaccine (called variant-adapted BNT162b2 RNA-based vaccine) in healthy children. The trial is divided into 5 individual studies or substudies based on age group and prior history of COVID-19 vaccinations. All participants in each of the 5 sub-studies will receive study vaccine as a shot depending on what group they are in. * Substudy A design: Phase 1 includes participa... Read More
Gender:
ALL
Ages:
Between 6 months and 11 years
Trial Updated:
05/13/2024
Locations: UAB Child Health Research Unit (CHRU), Birmingham, Alabama +124 locations
Conditions: SARS-CoV-2 Virus, Severe Acute Respiratory Syndrome Coronavirus 2, COVID-19
Improving Medication Adherence Using Family-focused and Literacy-sensitive Strategies
Recruiting
People with heart failure who do not take their medications as prescribed are at high risk of complications leading to hospitalization, death and poor quality of life. In the proposed intervention, nurses will use easy-to-understand language to coach patients and their care partners to help them work together and build skills to overcome their individual barriers to adherence in order to 1) improve and sustain patient medication adherence; 2) reduce hospitalization; 3) improve quality of life. I... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/13/2024
Locations: Jia-Rong Wu, Lexington, Kentucky
Conditions: Medication Adherence, Heart Failure
Study of DF9001 in Patients With Advanced Solid Tumors
Recruiting
DF9001-001 is a study of a new molecule that targets natural killer (NK) cells and T-cell activation signals to specific receptors on cancer cells. The study will occur in two phases. The first phase will be a dose escalation phase, enrolling patients with various types of solid tumors that express epidermal growth factor receptor (EGFR). The second phase will include a dose expansion using the best dose selected from the first phase of the study. Multiple cohorts will be opened with eligible pa... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/13/2024
Locations: Banner MD Anderson, Gilbert, Arizona +16 locations
Conditions: Solid Tumor, Adult
Screening and Nutrition for Patients With Diabetes: A Pilot Study
Recruiting
The goal of this project is to provide diabetes self-management education and support (DSMES) and simultaneously address food insecurity for a high-risk, ethnically diverse adult population who participate in a food pantry. This project will utilize a Community-Based Participatory Research model (CBPR). Community representatives will engage in project implementation by participating in designing the messaging for cultural impact and advising in study operations. This intervention targets food pa... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/13/2024
Locations: Villanova University, Villanova, Pennsylvania
Conditions: Diabetes Mellitus
Predictors of Aspirin Failure in Preeclampsia Prevention
Recruiting
Hypertensive disorders of pregnancy (including preeclampsia) are among the leading causes of pregnancy complications and maternal deaths worldwide. They also increase the risks to the babies. Numerous interventions have been suggested in order to reduce the rate of preeclampsia. Low-dose aspirin is the most beneficial prophylactic approach in this regard. Nevertheless, aspirin failure is not uncommon. The genetic, laboratory, and clinical factors associated with low-dose aspirin failure in the p... Read More
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
05/13/2024
Locations: Rockefeller University, New York, New York
Conditions: Preeclampsia
PVI to Prevent S. Aureus SSI After Fixation of HELEF (POTENT Study)
Recruiting
The purpose of this study is to see whether applying povidone iodine (PVI) to the noses of patients undergoing lower extremity (leg, ankle, or foot) orthopedic fixation procedures of high-energy lower extremity fractures (HELEF) will decrease the patients' risk of surgical site infections (SSI), particularly those caused by Staphylococcus aureus.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/13/2024
Locations: Emory University, Atlanta, Georgia +5 locations
Conditions: Surgical Site Infection
Serious Gaming for Chemotherapy-induced Nausea and Vomiting
Recruiting
The purpose of this study is to examine the effectiveness of a technology-based intervention for managing nausea and vomiting in older adults with cancer. Participants will be randomized to either an intervention or control group. Outcomes such as symptom severity, quality of life, and resource use will be examined.
Gender:
ALL
Ages:
60 years and above
Trial Updated:
05/13/2024
Locations: Miller School of Medicine Sylvester Comp. Cancer Center, Miami, Florida +1 locations
Conditions: Neoplasms, Chemotherapy-induced Nausea and Vomiting