Does Psychoeducation Improve the Pain Relief Derived From a Brief Intervention
NCT06952049
Recruiting
This project is a single-site, five-arm, randomized controlled trial investigating whether providing patients in an orthopedic clinic waiting room psychoeducation about mindfulness impacts the degree of pain relief they experience during a mindfulness-based intervention.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/13/2025
Locations: Tallahassee Orthopedic Clinic (TOC), Tallahassee, Florida
Conditions: Pain, Acute Pain
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DECIDE to Improve Maternal Mental Health Care Delivery
NCT07098260
Recruiting
Appropriate training for perinatal mental health care is an important public health concern as mental health disorders are common pregnancy complications. Perinatal and mental health care providers report the difficulty of treating perinatal individuals due to insufficient information available regarding mental health treatment decisions, differences in beliefs and attitudes, and concerns about adverse effects on patients, such as self-harm and suicide. Effective shared decision-making skills ca... Read More
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
08/13/2025
Locations: Rutgers, the State University of New Jersey, Piscataway, New Jersey
Conditions: Mental Health Disorders
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A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease
NCT06679140
Recruiting
The purpose of the study is to evaluate whether ibuzatrelvir is effective and safe in adults and adolescents with COVID-19 who do not need to be in the hospital but who are at high risk for progression to severe disease. Eligible participants will be randomly assigned (by chance) to receive ibuzatrelvir or matching placebo orally for 5 days. Co-administration of locally available standard of care is allowed. The total duration of the study is around 6 months.
Gender:
ALL
Ages:
12 years and above
Trial Updated:
08/13/2025
Locations: Applied Research Center of Arkansas, Little Rock, Arkansas +143 locations
Conditions: COVID-19 SARS-CoV-2 Infection
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Mayo Clinic Health System Northwest Wisconsin Integrated Maternal Postpartum Appointment Combination
NCT06395168
Recruiting
The purpose of this study is to explore whether combining the first post-hospital newborn provider visit and lactation consultation into a single appointment can enhance rates of successful breastfeeding initiation and continuation at predefined intervals (e.g., one week, one month, two months, three months, four months, six months, and 12 months postpartum).
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
08/13/2025
Locations: Mayo Clinic Health System-Eau Claire Clinic, Eau Claire, Wisconsin
Conditions: Breast Feeding
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A Study to Examine Anktiva for the Treatment of COVID-19.
NCT07123727
Recruiting
This study will examine the safety and effectiveness of Anktiva in treating patients with Long COVID-19 which is defined as persistent symptoms of a COVID-19 infection that remain after the infection is over.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
08/13/2025
Locations: Chan Soon-Schiong Institute for Medicine (CSSIFM), El Segundo, California
Conditions: Long COVID, Long COVID Syndrome, Long Covid 19
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A Phase IIb Randomized, Multicenter Trial of Subretinal CPCB-RPE1 in Advanced Dry AMD (Geographic Atrophy)
NCT06557460
Recruiting
This is a Phase IIb randomized, clinical trial designed to assess the safety and efficacy of unilateral implantation of the CPCB-RPE1 implant in subjects with geographic atrophy involving the fovea. Up to 6 surgical implantation sites will deliver the CPCB-RPE1 in this Phase IIb clinical trial. Additional study sites may serve as referral or follow-up sites. Twenty-four (24) subjects will participate in the trial and will be randomized 3:1 to one of 2 groups: * The treatment group receiving th... Read More
Gender:
ALL
Ages:
Between 55 years and 90 years
Trial Updated:
08/13/2025
Locations: Retina-Vitreous Associates Medical Group, Beverly Hills, California +4 locations
Conditions: Dry Age-related Macular Degeneration, Geographic Atrophy
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Exploring the Effect of the Transcendental Meditation® Technique on Migraine Frequency and Functionality: A Single Arm Study
NCT06695156
Recruiting
This research will explore the effect of the Transcendental Meditation® Technique on migraine intensity and frequency. It will be a single-arm pilot study involving 30 participants recruited from migraine treatment facilities and support groups in the US.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
08/13/2025
Locations: Georgetown Headache Center and DC area, Washington, District of Columbia
Conditions: Migraine, Migraine with or Without Aura
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Expanding Access to Cervical Cancer Screening Through Primary HR-HPV Testing and Self-sampling: a Multicomponent Intervention for Safety Net Health Systems
NCT06843720
Recruiting
To learn about the attitudes toward implementing self-collection among healthcare providers and staff, participants, and other stakeholders; and to inform the development of patient education and provider training materials to aid in the implementation of self-collection in clinical settings.
Gender:
FEMALE
Ages:
Between 18 years and 65 years
Trial Updated:
08/13/2025
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: HR-HPV Testing
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A Study to Test if TEV-56286 is Effective in Relieving Multiple System Atrophy (MSA): A Safety and Efficacy Study
NCT06568237
Recruiting
The primary objective of the study is to evaluate the efficacy of TEV-56286 administered orally for the treatment of adult participants with Multiple System Atrophy (MSA). A secondary objective of the study is to evaluate specific efficacy parameters of TEV-56286. Another secondary objective is to evaluate the safety and tolerability of TEV-56286. The planned study period per participant is 56 weeks including a screening period (up to 4 weeks), a 48-week double-blind treatment period, and a f... Read More
Gender:
ALL
Ages:
30 years and above
Trial Updated:
08/13/2025
Locations: Teva Investigational Site 15554, La Jolla, California +47 locations
Conditions: Multiple System Atrophy
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A Phase 3, Placebo-controlled, Double-blind Study Assessing Rocatinlimab in Prurigo Nodularis
NCT06527404
Recruiting
The main objective of the study will be to evaluate the efficacy of rocatinlimab compared with placebo at week 24 on the patient-reported outcome (PRO) measure of pruritus and overall clinical assessment score (US only).
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
08/13/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama +191 locations
Conditions: Prurigo Nodularis
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Closed-Loop Deep Brain Stimulation for Treatment-Resistant Bipolar Depression
NCT07127913
Recruiting
Neurons are specialized types of cells that are responsible for carrying out the functions of the brain. Neurons communicate with electrical signals. In diseases such as major depression this electrical communication can go awry. One way to change brain function is using electrical stimulation to help alter the communication between groups of neurons in the brain. The purpose of this study is to test a personalized approach to brain stimulation as an intervention for bipolar depression The stud... Read More
Gender:
ALL
Ages:
Between 22 years and 70 years
Trial Updated:
08/13/2025
Locations: University of California, San Francisco, San Francisco, California
Conditions: Bipolar II Disorder, Bipolar II Disorder, Most Recent Episode Major Depressive
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Aromatherapy Essential Oils to Manage Anxiety and Nausea in Cancer Patients Receiving Infusion in the Ambulatory Setting
NCT07126301
Recruiting
This clinical trial tests how well aromatherapy essential oils work to manage anxiety and nausea in cancer patients receiving infusions in the ambulatory setting. Current drugs that are given for nausea may cause constipation and fatigue. Therefore, there is interest in exploring complementary therapies, like aromatherapy, that do not carry the same side effects. Using aromatherapy essential oils such as ginger, peppermint, and lavender, may help reduce nausea and anxiety. Some studies have show... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/13/2025
Locations: City of Hope Medical Center, Duarte, California +1 locations
Conditions: Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
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