Treatment of Ocular Demodex Infestation With Topical Ivermectin Cream 1%
NCT05213585
Recruiting
Patients with Demodex infestation of the eyelids will have the sleeves from both eyes cleaned off with microblepharoexfoliation. Afterwards, one eye will be randomly selected for treatment with topical ivermectin 1% cream. The treatment will be repeated on that eye 2 weeks later. Afterwards, the patients will present monthly for photographs of the eyelashes. The photographs will be reviewed by an ophthalmologist outside of our institution who will be blind to which eye was treated and independen... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/20/2022
Locations: Helm Vision Group, Santa Clarita, California
Conditions: The Focus of the Study is to Assess the Effectiveness of Topical Ivermectin on Eliminating Eyelash Sleeves
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Sorrel 25R Injector - Sorrel Clinical Study Protocol
NCT05221333
Recruiting
A prospective, open-label, single-center pilot study to evaluate the performance, safety and usability of the investigational SWI Device in healthy volunteers.
Gender:
All
Ages:
Between 18 years and 40 years
Trial Updated:
01/20/2022
Locations: Thomas Jefferson University Hospital, Philadelphia, Pennsylvania
Conditions: Injection Site, Injection Site Reaction, Injection Site Irritation
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Pilot Study: KeraStat® Gel for Topical Delivery of Morphine for Management of Non-Healing, Painful Open Wounds and Ulcers
NCT05217160
Recruiting
This study is intended to provide information from subjects who currently have painful, chronically open wounds and assess the pain reduction capacity of KeraStat® Gel with Morphine. In gathering data from subjects who have baseline pain from their chronically open wounds, the investigators can then evaluate the capacity of KeraStat® Gel plus Morphine in reducing the subjects daily pain levels, pain associated with dressing changes, and pain medication consumption.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/19/2022
Locations: South Texas Aesthetic and Reconstructive Surgery, San Antonio, Texas
Conditions: Wound of Skin, Burns
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Qualification for Cone-Optogenetics
NCT05218928
Recruiting
This study aims to prepare for the first-in-human clinical trial of cone optogenetics vision restoration. As a first step, this worldwide multicenter ocular imaging study (EyeConic Study) is performed to identify eligible patients.
Gender:
All
Ages:
All
Trial Updated:
01/19/2022
Locations: University of California San Francisco, Department of Ophthalmology, San Francisco, California +8 locations
Conditions: Retinal Dystrophies
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Dose-Escalation and Dose-Expansion Study of ZX-4081 in Patients With Advanced Solid Tumors
NCT05118841
Recruiting
A Phase 1, first-in-human, open-label, multicenter, dose escalation and dose expansion study to investigate the safety, tolerability, PK, pharmacodynamics, and preliminary antitumor activity of ZX-4081 administered orally (PO) twice daily (BID) in 28-day cycles in patients with Advanced Solid Tumors.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/18/2022
Locations: Carolina BioOncology, Huntersville, North Carolina
Conditions: Advanced Solid Tumor
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Spine Registration Using 3D Scanning - Arise
NCT05195593
Recruiting
The primary objective is to assess the capability of the device as measured by its consistency, its accuracy, and feedback from surgical staff over the study period.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/17/2022
Locations: Arise Austin Medical Center, Austin, Texas
Conditions: Spinal Fusion, Spondylolisthesis, Scoliosis, Sciatica
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Spine Registration Using 3D Scanning
NCT05195580
Recruiting
The primary objective is to assess the capability of the device as measured by its consistency, its accuracy, and feedback from surgical staff over the study period.
Gender:
All
Ages:
All
Trial Updated:
01/17/2022
Locations: St. David's Round Rock Medical Center, Round Rock, Texas
Conditions: Spinal Fusion, Spinal Stenosis, Scoliosis, Spondylolisthesis
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Clinical and Radiographic Outcomes of TLIF w/3D Printed Cellular Implant
NCT05023733
Recruiting
This study is designed to evaluate clinical outcomes and spine fusion rates for patients undergoing transforaminal lumbar interbody fusion using the CONDUIT 3D printed titanium TLIF cage.
Gender:
All
Ages:
Between 35 years and 80 years
Trial Updated:
01/14/2022
Locations: Hartford Healthcare Bone and Joint Institute, Hartford, Connecticut
Conditions: Foraminal Stenosis, Degenerative Disc Disease, Lumbar Spondylolisthesis, Lumbar Spinal Stenosis
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Study of Acalabrutinib (ACP-196) in Combination With Venetoclax (ABT-199), With and Without Obinutuzumab (GA101) Versus Chemoimmunotherapy for Previously Untreated CLL
NCT05211856
Recruiting
The purpose of this study is to evaluate the efficacy and safety of acalabrutinib in combination with venetoclax and acalabrutinib in combination with venetoclax with and without obinutuzumab compared to chemoimmunotherapy in subjects with previously untreated CLL.
Gender:
All
Ages:
Between 18 years and 130 years
Trial Updated:
01/14/2022
Locations: Research Site, Fountain Valley, California +277 locations
Conditions: Chronic Lymphocytic Leukemia
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McKenzie Method of Mechanical Diagnosis and Therapy for Management of Cervicogenic Headache: A Prospective Case Series
NCT05212844
Recruiting
The goal of this study is to examine the effectiveness the Mechanical Diagnosis and Therapy (MDT) approach for the management patients with neck related headache that are referred to a hospital based out-patient physical therapy clinic. Background: Headache conditions are among the most common complaints causing people to seek medical care. An estimated 14 billion dollars are spent annually on treating headaches. Neck related headache is characterized by pain which comes from the cervical spine... Read More
Gender:
All
Ages:
Between 19 years and 70 years
Trial Updated:
01/14/2022
Locations: Faith Regional Rehabilitation Therapies, Norfolk, Nebraska
Conditions: Cervicogenic Headache
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Screening Protocol for Children and Adolescents With Bipolar and Bipolar Spectrum Disorder
NCT00592267
Recruiting
The objective of this protocol is to establish a comprehensive screening process for the evaluation of eligibility for entry in a clinical trial program for children and adolescents with bipolar disorder.
Gender:
All
Ages:
Between 4 years and 17 years
Trial Updated:
01/14/2022
Locations: Masschusetts General Hospital, Boston, Massachusetts
Conditions: Pediatric Bipolar Disorder
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Bladder Tumor Biopsy Study to Improve Preoperative Determination of Stage and Grade
NCT02992990
Recruiting
To assess whether the addition of a bladder tumor biopsy improves the level of agreement between the pretreatment endoscopic impression and the final postoperative pathology determination of stage and grade in non-muscle-invasive urothelial carcinoma of the bladder.
Gender:
All
Ages:
21 years and above
Trial Updated:
01/14/2022
Locations: Baylor College of Medicine, Houston, Texas
Conditions: Bladder Cancer
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