Dual Joint Visual Feedback Gait Retraining in Pediatric Hemiplegic Cerebral Palsy
NCT05011201
Recruiting
This study aims to assess the feasibility of a visual feedback system designed to augment treadmill-based gait training for children with gait disturbances related to hemiplegic cerebral palsy. The visual feedback uses data from knee and hip joint movements to represent the position of the foot ahead of or behind the body during walking. This study will test eight children with hemiplegic cerebral palsy who have short step lengths related to atypical knee and hip motions when the foot contacts t... Read More
Gender:
All
Ages:
Between 7 years and 17 years
Trial Updated:
01/14/2022
Locations: Kessler Foundation, West Orange, New Jersey
Conditions: Hemiplegic Cerebral Palsy
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Clinical and Radiographic Outcomes of TLIF w/3D Printed Cellular Implant
NCT05023733
Recruiting
This study is designed to evaluate clinical outcomes and spine fusion rates for patients undergoing transforaminal lumbar interbody fusion using the CONDUIT 3D printed titanium TLIF cage.
Gender:
All
Ages:
Between 35 years and 80 years
Trial Updated:
01/14/2022
Locations: Hartford Healthcare Bone and Joint Institute, Hartford, Connecticut
Conditions: Foraminal Stenosis, Degenerative Disc Disease, Lumbar Spondylolisthesis, Lumbar Spinal Stenosis
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Study of Acalabrutinib (ACP-196) in Combination With Venetoclax (ABT-199), With and Without Obinutuzumab (GA101) Versus Chemoimmunotherapy for Previously Untreated CLL
NCT05211856
Recruiting
The purpose of this study is to evaluate the efficacy and safety of acalabrutinib in combination with venetoclax and acalabrutinib in combination with venetoclax with and without obinutuzumab compared to chemoimmunotherapy in subjects with previously untreated CLL.
Gender:
All
Ages:
Between 18 years and 130 years
Trial Updated:
01/14/2022
Locations: Research Site, Fountain Valley, California +277 locations
Conditions: Chronic Lymphocytic Leukemia
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Remote Monitoring of Home Exercise in Peripheral Arterial Disease
NCT05209724
Recruiting
Many patients with blockages in the arteries in their legs (peripheral arterial disease, "PAD") suffer from pain in their legs when walking. Exercise therapy is known to decrease pain levels as well as increase the distance that patients with PAD can walk. The purpose of this study is to understand whether home exercise using a digital exercise monitoring system (LIVMOR) with provider supervision/ feedback will improve walking distance compared to those undergoing home exercise using the same mo... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/13/2022
Locations: Dallas North Texas Veterans Affairs Hospital, Dallas, Texas
Conditions: Peripheral Arterial Disease
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Respiratory Strength Training in Cardiac Surgical Patients
NCT04887415
Recruiting
Swallowing difficulty (dysphagia) is a common postoperative complication in patients who undergo cardiac surgical procedures. Postoperative dysphagia in cardiac surgical patients is associated with negative health-related outcomes including increased rates of pneumonia, reintubation, and death as well as increased length of hospital stay and costs of care. This study will examine the safety, feasibility, and impact of preoperative respiratory strength training (RST) on swallowing and associated... Read More
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
01/13/2022
Locations: Cardiovascular Clinic and Thoracic/Cardiovascular Surgery at UF Health, Gainesville, Florida
Conditions: Cardiovascular Diseases, Thoracic Diseases, Surgery, Surgery--Complications, Dysphagia
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Direct Peritoneal Resuscitation for Intra-abdominal Catastrophes
NCT05208489
Recruiting
It is a retrospective study. Patients, who presented with either traumatic or general surgery emergencies, undergone exploratory laparotomy, had an open abdomen management and received Direct Peritoneal Resuscitation in addition to standard resuscitation will be considered as meeting the criteria to collect the data.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/13/2022
Locations: New York Medical College, Valhalla, New York
Conditions: Intestinal Perforation, Intestinal Obstruction, Trauma Abdomen
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Advancing Dignity, Health, and Optimism in Connection With Long Acting Injectables
NCT05208541
Recruiting
ADHOC-LA is an observational study of people living with HIV who either are taking, or have taken, a long-acting injectable therapy to manage their HIV. Data from this study will be used to research the ways in which HIV impacts the lives of these patients.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/13/2022
Locations: Mazonson & Santas Inc, Menlo Park, California
Conditions: HIV
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Multicenter Outcome Registry of AnaLgesic Effect of SCS(MORALES) Registry Protocol
NCT04548375
Recruiting
The objective is to provide information to help the physician community decide the most effective type of device/therapy that would work for their patients, based off of the etiology of pain, the location of the pain for sustained pain relief.
Gender:
All
Ages:
All
Trial Updated:
01/12/2022
Locations: Summit Surgery Center, Reno, Nevada
Conditions: SCS
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A Prospective Biomarker Study in Active SPMS Subjects Treated With Cladribine Tablets
NCT04550455
Recruiting
The purpose of this study is to explore the concept that biomarker sensitivity will detect activity in Multiple Sclerosis (MS) subjects and allow appropriate change in treatment to prevent dysfunction.
Gender:
All
Ages:
Between 21 years and 65 years
Trial Updated:
01/12/2022
Locations: Multiple Sclerosis Center of Northeastern New York, P.C., Latham, New York
Conditions: Multiple Sclerosis
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ACute Uncomplicated Type b Aortic Dissection: Endovascular Repair vs. Best Medical Therapy
NCT02622542
Recruiting
The purpose of the study is to conduct a randomized controlled trial comparing best medical therapy (BMT) alone to BMT with thoracic endovascular aortic repair (BMT+TEVAR) for uncomplicated acute type B aortic dissection.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/11/2022
Locations: Department of Cardiothoracic and Vascular Surgery and Memorial Hermann Heart and Vascular Institute - Texas Medical Center, Houston, Texas +1 locations
Conditions: Distal Aortic Dissection, Dissection, Aortic Acute, Acute Type B Aortic Dissection (Uncomplicated)
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CGX1321 in Subjects With Advanced Solid Tumors and CGX1321 With Pembrolizumab or Encorafenib + Cetuximab in Subjects With Advanced GI Tumors (Keynote 596)
NCT02675946
Recruiting
This is a multicenter, open-label study conducted in two phases: Phase 1 consisting of a CGX1321 Single Agent Dose Escalation Phase in solid tumors, CGX1321 Single Agent Dose Expansion Phase in GI tumors and Roll-over Cohort of CGX1321 and pembrolizumab in subjects who have progressed on single agent CGX1321 and Phase 1b consisting of CGX1321 in combination with pembrolizumab in colorectal tumors and CGX1321 in combination with encorafenib + cetuximab in BRAFV600E mutated colorectal tumors. Both... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/11/2022
Locations: Memorial Care, Long Beach, California +25 locations
Conditions: Solid Tumors, GI Cancer
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The EMPOWER Study: Endometriosis Diagnosis Using microRNA
NCT04598698
Recruiting
Endometriosis is a complex, heterogeneous disease that may present inconsistently across women. Using disease-specific biomarkers and advanced biostatistics, DotLab is developing a biomarker test to confirm the presence of endometriosis.This is a multi-center, prospective, observational, minimal risk study in women undergoing laparoscopy, laparotomy or other pelvic surgical procedure for endometriosis, infertility or another benign gynecological indication. Participants will undergo 2 study visi... Read More
Gender:
Female
Ages:
Between 18 years and 49 years
Trial Updated:
01/11/2022
Locations: Stanford University Hospital, Palo Alto, California +22 locations
Conditions: Endometriosis
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