Botanical Blend on the Gut Microbiome and Gut-Skin-Axis in Small Intestinal Bacterial Overgrowth (SIBO)
NCT04867512
Recruiting
The purpose of this study is to assess how an oral botanical blend alters the gut microbiome and the skin biophysical properties in people with SIBO.
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
04/29/2021
Locations: Integrative Skin Science and Research, Sacramento, California
Conditions: Small Intestinal Bacterial Overgrowth (SIBO)
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On Site Sensors Monitoring Impacts of Cognitive Decline on ADLs
NCT04871698
Recruiting
The purpose of this research is to compare the effectiveness of a continuous monitoring system to assess Activities of Daily Living (ADLs) over time compared to the traditional assessments used by medical professionals as Alzheimer's Disease and Alzheimer's Disease Related Dementias (AD/ADRD) progresses.
Gender:
All
Ages:
65 years and above
Trial Updated:
04/29/2021
Locations: Birkeland Current, Waco, Texas
Conditions: Dementia, Dementia Alzheimers
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Waveform and Spectral Characteristics of Perioperative Wheezing
NCT04873882
Recruiting
With the aid of computerized sound analysis, digital acoustic monitoring could provide a more sensitive, specific, and quantifiable indicator for perioperative respiratory abnormalities including wheezing. It is probable that the digital stethoscope has utility in the detection, monitoring, and resolution following treatment of acoustic changes characteristic of turbulent respiratory gas flow due to wheezing and/or the incomplete resolution of atelectasis following the re-initiation of ventilati... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/29/2021
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Respiratory Sounds, Thoracic Surgery
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Study Investigating the Efficacy of Crenolanib With Chemotherapy vs Chemotherapy Alone in R/R FLT3 Mutated AML
NCT03250338
Recruiting
This is a randomized, multi-center, double-blind, placebo-controlled study designed to evaluate the efficacy of crenolanib administered following salvage chemotherapy, consolidation chemotherapy, post bone marrow transplantation and as maintenance in relapsed/refractory AML subjects with FLT3 activating mutation.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
04/28/2021
Locations: City of Hope National Medical Center, Sacramento, California +61 locations
Conditions: Relapsed/Refractory Acute Myeloid Leukemia With FLT3 Activating Mutations
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Designing a Predictive Tool to Identify Whether a Cancer Patient Has Bacteremia Due to Ceftriaxone-Resistant Escherichia Coli
NCT04866186
Recruiting
This study aims to develop a tool to predict whether a cancer patient has bacteria in the blood (bacteremia) due to ceftriaxone-resistant Escherichia (E.) coli. This study may help researchers identify risk factors for ceftriaxone-resistant E. coli bacteremia in cancer patients and improve antibiotic treatment in these patients.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/28/2021
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Escherichia Coli Infection, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
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Cancer Therapy Effects on the Heart
NCT04262830
Recruiting
Anthracycline chemotherapies (e.g. doxorubicin, daunorubicin) are commonly given to treat pediatric cancer, and carry a risk of cardiotoxicity. Over the long term, children who receive these therapies have an increased risk of heart failure and early cardiovascular death. However, current strategies for identifying patients who are at risk prior to the development of significant changes in heart function are limited. This study will focus on imaging markers of cardiac injury and dysfunction with... Read More
Gender:
All
Ages:
Between 13 years and 39 years
Trial Updated:
04/27/2021
Locations: Rady Children's Hospital, San Diego, California
Conditions: Cardiotoxicity, Pediatric Cancer, Heart Failure
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Physical Rehabilitation of COVID-19 Survivors by Heat Therapy
NCT04673318
Recruiting
Older adults and people with underlying medical conditions are at higher risk for developing serious complications related to SARS-CoV-2 resulting in prolonged sequelae. The goal of this proposal is to compare the benefits of home-based lower limb heat therapy to exercise training on cardio-metabolic function and mobility in older adults during their convalescence from hospitalization due to SARS-CoV-2.
Gender:
All
Ages:
Between 55 years and 85 years
Trial Updated:
04/27/2021
Locations: Institute of Applied Life Sciences, Amherst, Massachusetts
Conditions: Covid19, Physical Disability
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Efficacy of Contrast Enhanced Voiding Urosonography for Urodynamic Studies
NCT04738539
Recruiting
The investigators will assess the feasibility of replacing fluoroscopy/iodinated contrast with ultrasound/sulfur hexafluoride lipid-type A microspheres during routine urodynamic studies.
Gender:
All
Ages:
18 years and below
Trial Updated:
04/27/2021
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Myelomeningocele, Neurogenic Bladder, Tethered Cord Syndrome, Bladder, Neurogenic, Urologic Diseases, Neurologic Dysfunction
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Telemedicine in Age-Related Macular Degeneration
NCT04863391
Recruiting
This study seeks to evaluate a system for the automated early detection of Age-Related Macular Degeneration (AMD). AMD is a condition in which there is breakdown of the macula of the eye, the part of the retina that is responsible for sharp, central vision. We will take pictures of subjects' eyes using an automated camera. These photographs will be securely transmitted and and then analyzed by a computer program which has been developed in other studies. The outcome of the computer program analy... Read More
Gender:
All
Ages:
50 years and above
Trial Updated:
04/26/2021
Locations: New York Eye and Ear Infirmary of Mount Sinai, New York, New York
Conditions: Age Related Macular Degeneration
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Evaluation Of Vision Recovery And Comfort Index In Patients With Borderline/Mild Dry Eyes Undergoing FLACS With Premium IOL
NCT04863742
Recruiting
This is a prospective, open-label, single-center, randomized, head-to-head, investigator-sponsored clinical study. It aims to investigate the vision recovery and patient comfort in borderline/mild dry eye disease patients undergoing FLACS with Premium PCIOL (i.e., Panoptix, Toric IOL (spherical/multifocal), ReStor, Symfony), receiving a 0.4mg dexamethasone intracanalicular insert when compared to patients receiving standard of care prednisolone acetate 1%.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/26/2021
Locations: SightMD, LIASC, Brentwood, New York
Conditions: Dry Eye Syndromes
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Does a ThoracoLumbar Interfacial Plane (TLIP) Block With Liposomal Bupivacaine Provide TLIP Block in Spinal Surgery
NCT04865211
Recruiting
The investigators are looking to recruit patients into a study demonstrating the effectiveness of a superficial nerve block involving the thoracolumbar interfascial plane (TLIP) in reducing postoperative pain in those undergoing spinal surgery
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
04/26/2021
Locations: Cooper University Hospital, Camden, New Jersey
Conditions: Pain, Postoperative
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Microgrid II - Electrocorticography Signals for Human Hand Prosthetics
NCT03289572
Recruiting
Neurologic disease with loss of motor function is a major health burden. Brain-computer interfaces (BCI) are systems that use brain signals to power an external device, such as a communication board or a prosthetic device, which may help people with loss of motor function. Electrocorticography (ECoG) has been used to decode hand movements and as a control signal for brain-computer interface (BCI). This study hopes to use a smaller spacing of ECoG to see if a better motor signal can be found and... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/26/2021
Locations: Harborview Medical Center, Seattle, Washington
Conditions: Epilepsy Intractable
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