All Clinical Trials

A listing of 23116 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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Featured Trial

Healthy Participants Needed (Colonoscopy + Cancer Screening)

Recruiting

Earn $325 - $475 in electronic payment card compensation for your time and effort by participating in a clinical study to develop a blood test that may one day help screen for colon cancer. Take a quick quiz to see if you qualify.

Conditions:

Healthy

Healthy Volunteers

Healthy Subjects

Healthy Volunteer

Healthy Participants

Learn More

Featured Therapy

Unique Treatment for High Blood Pressure

Worried about high blood pressure? Think beyond typical high blood pressure treatments.

People who may be candidates for this procedure:

• Are at least 18 years old
• Have been unable to manage their high blood pressure with medications or lifestyle changes alone¹

Learn about a safe and effective procedure that may help reduce high blood pressure. See if you qualify today.

¹ Kandzari DE, et al. J Am Coll Cardiol. Nov 7, 2023;82(19):1809-1823.

Conditions:

High Blood Pressure

High Blood Pressure (& [Essential Hypertension])

High Blood Pressure (Hypertension).

Hypertension

Essential Hypertension

Learn More

Featured Trial

Paid Clinical Studies Nationwide

Recruiting

Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.

Conditions:

Healthy

Healthy Volunteer Study

Learn More

Featured Trial

Discover Clinical Trials In Your Area (Compensation Provided)

Recruiting

Clinical trials in your area are actively enrolling — and they compensate you for your time. Finding the right one has never been easier.

- Matched to trials in your zip code
- Compensation for time & travel
- Free or low-cost treatments available
- No experience or medical background needed
- Takes just 30 seconds to see if you qualify

Conditions:

Healthy

Healthy Volunteers

Learn More

Featured Offer

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Get $50 off your first order using promo code: policy-lab-50

Conditions:

Overweight

Overweight and Obesity

Obesity

Weight Loss

Morbid Obesity

Learn More

Featured Trial

COVID-19 Vaccine Clinical Trial (Compensation Provided)

Recruiting

Healthy adults ages 50-64 may qualify. You may be eligible if you haven’t received a COVID-19 vaccine and haven’t had COVID-19 in the last 90 days.

Qualified participants may receive compensation for time and travel.

Conditions:

Healthy

Vaccine

COVID19

COVID-19

COVID-19 Vaccine

Learn More

A Study to Evaluate the Efficacy and Safety of Deucravacitinib in Adults With Active Sjögren's Syndrome

NCT05946941

Recruiting

The purpose of this study is to assess the safety and efficacy of two doses of Deucravacitinib in adult participants with Active Sjögren's Syndrome.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/11/2025

Locations: Local Institution - 0228, Fullerton, California +228 locations

Local Institution - 0228, Fullerton, California

Arthritis and Osteoporosis Medical Center, La Palma, California

UCSF Univ of California San Francisco, San Francisco, California

Providence St. John's Health Center, Santa Monica, California

Denver Arthritis Clinic, Denver, Colorado

Clinical Research of West Florida; Inc, Clearwater, Florida

GNP Research, Cooper City, Florida

Sarasota Arthritis Center, Sarasota, Florida

Augusta University, Augusta, Georgia

Local Institution - 0229, Lawrenceville, Georgia

Clinic of Robert Hozman/Clinical Investigation Specialists Inc., Skokie, Illinois

University of Kansas Medical Center, Kansas City, Kansas

Local Institution - 0123, Hopkinsville, Kentucky

Ochsner Health Center - Baton Rouge, Baton Rouge, Louisiana

Local Institution - 0125, Monroe, Louisiana

Johns Hopkins Medicine - Jerome L. Greene Sjogrens Syndrome Center, Baltimore, Maryland

Tufts Medical Center, Boston, Massachusetts

Saint Paul Rheumatology, Eagan, Minnesota

Institute for Rheumatic & Autoimmune Diseases; Overlook Medical Center, Summit, New Jersey

Local Institution - 0009, Albuquerque, New Mexico

NYU Langone Hospital - Long Island, Mineola, New York

Onsite Clinical Solutions, Salisbury, North Carolina

Local Institution - 0132, Corvallis, Oregon

Altoona Center for Clinical Research, Duncansville, Pennsylvania

Local Institution - 0022, Jackson, Tennessee

Arthritis & Rheumatology Research Institute; PLLC, Allen, Texas

Biopharma Informatic, Katy, Texas

Local Institution - 0175, Plano, Texas

Local Institution - 0225, The Woodlands, Texas

Local Institution - 0133, Seattle, Washington

Arthritis Northwest, Spokane, Washington

IMAC SI, San Isidro, Alabama

Iro Research, Caba, Buenos Aires

CER Instituto Medico, Quilmes, Buenos Aires

Centro de Investigaciones Medicas Tucuman, San Miguel de Tucuman, Tucuman

Centro Medico del Dr Javier Tartaglione, Buenos Aires, Not set

Local Institution - 0058, Buenos Aires, Not set

IME Instituto medico Especializado, Caba, Not set

Centro Barrio Parque - Swiss Medical, City of Buenos Aires, Not set

Consultora Integral de Salud SRL, Cordoba, Not set

Local Institution - 0039, Cordoba, Not set

The Queen Elizabeth Hospital, Woodville South, South Australia

Local Institution - 0165, Nedlands, Western Australia

Medical University of Graz, Graz, Not set

Local Institution - 0087, Wien, Not set

Local Institution - 0183, Aalst, Not set

UZ Gent, Gent, Not set

Hospital Universitario Cassiano Antonio Moraes, Vitoria, ES

Cmip-Centro Mineiro de Pesquisa, Juiz de Fora, MG

Universidade Federal de Minas Gerais (UFMG) - Faculdade de Medicina, Belo Horizonte, Minas Gerais

Hospital Moinhos de Vento, Porto Alegre, RS

CEPIC Centro Paulista de Investigacao Clinica, Sao Paulo, SP

Universidade Federal de Uberlandia (UFU) - Campus Santa Monica - Centro de Pesquisa Clinica, Uberlandia, Not set

Local Institution - 0008, Plovdiv, Not set

ARENSIA Research Clinic MBAL Sveta Sofia, Sofia, Not set

Sjogren's Clinic at the Mary Pack Arthritis Center, Vancouver, British Columbia

University Health Network - Toronto Western Hospital, Toronto, Ontario

Diex Recherche Sherbrooke, Sherbrooke, Quebec

Centre De Recherche Musculo-Squelettique, Trois Rivières, Quebec

Clinical Research Chile SpA, Valdivia, LOS Lagos

Local Institution - 0103, Valdivia, Los Rios

BioMedica Research Group, Santiago, Metropolitana

Centro de Estudios Reumatologicos, Santiago, Providencia

Local Institution - 0015, Santiago De Chlie, Region Metropolitana

CIERI, Vina Del Mar, Valparaiso

Local Institution - 0099, Osorno, Not set

Estudios Clinicos GyC, Santiago, Not set

Local Institution - 0121, Santiago, Not set

Peking University First Hospital (Beida Hospital) (No.1 Hospital Affiliated to Beijing Medical University), Beijing Shi, Beijing

Peking University People's Hospital - Institute of Rheumatology and Immunology, Beijing, Beijing

Peking University Third Hospital, Beijing, Beijing

Local Institution - 0096, Chongqing, Chongqing

The First Affiliated Hospital of Xiamen University, Xiamen, Fujian

Guangdong Provincial People's Hospital, Guangzhou, Guangdong

Shenzhen Peoples Hospital, Shenzhen, Guangdong

Local Institution - 0180, Luoyang, Henan

1st Hospital of Zhengzhou University, Zhengzhou, Henan

Tongji Hospital affiliated to Huazhong University of Science and Technology, Wuhan, Hubei

The Second Xiangya Hospital of Central South University, Changsha, Hunan

Hunan Province People's Hospital, Changsha, Hunan

Local Institution - 0098, Baotou Shi, Inner Mongolia

Local Institution - 0150, Hohhot, Inner Mongolia

Nanjing Drum Tower hospital, Nanjing, Jiangsu

Nanjing Medical University (NMU) - Jiangsu Province Hospital (First Affiliated Hospital), Nanjing, Jiangsu

Ningbo First Hospital, Ningbo, Jiangsu

Local Institution - 0154, Suzhou, Jiangsu

Local Institution - 0163, Jiujiang, Jiangxi

1st Hospital of Nanchang University, Nanchang, Jiangxi

Jiangxi Provincial Peoples Hospital, Nanchang, Jiangxi

Pingxiang Peoples Hospital, Pingxiang, Jiangxi

The First Affiliated Hospital of Xian Jiaotong University, Xian, Shaanxi

Shanxi Bethune Hospital;Shanxi Academy of Medical Sciences, Taiyuan, Shan1xi

Shanghai 9th Peoples Hospital, Shanghai Shi, Shanghai Sheng

Renji Hospital Affiliated to Shanghai Jiaotong University School of Medicine -Shanghai Institute of Rheumatology, Shanghai, Shanghai

Tongji University - Tongji Hospital, Shanghai, Shanghai

West China Hospital Sichuan University, Chengdu, Sichuan

Xinjiang Uygur Autonomous Region People's Hospital, Urumqi, Xinjiang Sheng

Local Institution - 0181, Hangzhou, Zhejiang

Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang

Wenzhou Medical University (WMU) - The First Affiliated Hospital, Wenzhou, Zhejiang

Local Institution - 0168, Barranquilla, Atlantico

Local Institution - 0043, Chica, Cundinamarca

Local Institution - 0037, Bogota D.C, Not set

Local Institution - 0186, Aarhus, Region Midt

Local Institution - 0006, Glostrup, Not set

Meilahti Triangle Hospital, Helsinki, Not set

Satucon Oy, Kuopio, Not set

Turku University Hospital, Turku, Not set

Hopital de la Pitie Salpetriere, Paris, Cedex 13

Local Institution - 0072, Orleans, Centre

CHU Amiens-Picardie - Site Nord Hopital Nord, Amiens, Not set

CHU de Bordeaux - Hopital Saint-Andre, Bordeaux, Not set

Local Institution - 0070, Grenoble, Not set

Groupe Hospitalier du Havre (GHH) - Hopital Jacques Monod, Le Havre Cedex, Not set

CHU Hpital de Bicetre Universit Paris 11, Le Kremlin-Bictre, Not set

Local Institution - 0078, Marseille, Not set

Hopital Saint Antoine, Paris, Not set

Hopital Cochin, Paris, Not set

Klinikum der Universitaet Muenchen LMU, Munich, Bayern

Charite University Hospitals, Berlin, Not set

University Hospital Freiburg, Freiburg, Not set

Hamburger Rheuma Forschungszentrum 2, Hamburg, Not set

Universitaetsklinikum Tuebingen, Tuebingen, Not set

Universitaetsklinikum Wuerzburg, Wuerzburg, Not set

National and Kapodistrian University of Athens NKUA - Laiko General Hospital, Athens, Not set

Local Institution - 0052, Athina, Not set

Local Institution - 0108, Larissa, Not set

Local Institution - 0115, Budapest, IX, Válassz Egy Opciót…

Local Institution - 0113, Budapest, Not set

Debreceni Egyetem - Orvos es Egeszsegtudomanyi Centrum (DEOEC) (University of Debrecen Medical and Health Science Center), Debrecen, Not set

Bekes Megyei Kozponti Korhaz Pandy Kalman Tagkorhaz, Gyula, Not set

Sheba Medical Center, Ramat Gan, IA

Meir Medical Center, Kfar Sava, Not set

Asst Spedali Civili Di Brescia, Brescia, Not set

ASST G. Pini-CTO, Milano, Not set

Università degli Studi della Campania Luigi Vanvitelli Napoli, Napoli, Not set

Local Institution - 0082, Padua, Not set

AOU Pisana, Pisa, Not set

Campus Biomedico University, Rome, Not set

Local Institution - 0062, Rome, Not set

Santa Maria della Misericordia, Udine, Not set

Kojunkai Daido Clinic, Nagoya-shi, Aichi

Fujita Health University Hospital, Toyoake-shi, Aichi

Hospital of the University of Occupational and Environmental Health, Kitakyushu-shi, Fukuoka

Hokkaido University Hospital, Sapporo-shi, Hokkaido

Sapporo Medical University Hospital, Sapporo, Hokkaido

Hyogo Medical University Hospital, Nishinomiya-shi, Hyogo

Tsukuba University Hospital, Tsukuba City, Ibaraki

Kanazawa Medical University Hospital, Kahoku-gun, Ishikawa

Kanazawa University Hospital, Kanazawa-shi, Ishikawa

St.Marianna University Hospital, Kawasaki-shi, Kanagawa

National Hospital Organization Yokohama Medical Center, Yokohama, Kanagawa

Tohoku University Hospital, Sendai-shi, Miyagi

Nagasaki University Hospital, Nagasaki-Shi, Nagasaki

Sasebo Chuo Hospital, Sasebo, Nagasaki

Kurashiki Medical Clinic, Kurashiki, Okayama

Shiga University of Medical Science Hospital, Otsu, Shiga

Hamamatsu University Hospital, Hamamatsu, Shizuoka

Dokkyo Medical University Hospital, Shimotsugagun, Tochigi

Juntendo University Hospital, Bunkyo-ku, Tokyo

Institute of Science Tokyo Hospital, Bunkyo-ku, Tokyo

St. Luke's International Hospital, Chuo-ku, Tokyo

Nihon University Itabashi Hospital, Itabashi City, Tokyo

National Hospital Organization Tokyo Medical Center, Meguro-ku, Tokyo

Toho University Ohashi Medical Center, Meguro-ku, Tokyo

Showa University East Hospital, Shinagawa-ku, Tokyo

Keio University Hospital, Shinjuku, Tokyo

Hanyang University Seoul Hospital, Seongdong-gu, Seoul

Local Institution - 0042, Gwangju, Not set

The Catholic University of Korea; Seoul St. Mary's Hospital, Seoul, Not set

Konkuk University Medical Center, Seoul, Not set

CINTRE - Centro de investigacion y tratamiento reumatologico, S.C., Mexico, Distrito Federal

Consultorio Medico de Reumatologia, Leon, Guanajuato

Investigacion Biomedica para el Desarrollo de Farmacos S.A de C.V, Guadalajara, Jalisco

Centro de Estudios de Investigacion Basica y Clinica S.C., Guadalajara, Jalisco

Local Institution - 0021, Chihuahua, Not set

Local Institution - 0046, Leeuwarden, Friesland

Universitair Medisch Centrum Groningen, Groningen, Not set

Erasmus Medisch Centrum, Rotterdam, Not set

ACQ Medic SAC, Jesus Maria, Lima

Instituto de Ginecologia y Reproduccion, Santiago de Surco, Lima

Clinica Internacional Sede Lima, Lima, Not set

Centrum Medyczne PLEJADY, Krakow, Malopolskie

MICS Centrum Medyczne Warszawa, Warszawa, Mazowieckie

Local Institution - 0141, Warszawa, Woj. Mazowieckie

Local Institution - 0010, Warszawa, Woj. Mazowieckie

MICS Centrum Medyczne Bydgoszcz, Bydgoszcz, Not set

Szpital Uniwersytecki nr 2 im.dr. Jana Biziela w Bydgoszczy, Bydgoszcz, Not set

Etg Network, Lublin, Not set

Med-Polonia Sp. zo.o., Poznan, Not set

Reuma Park Warszawa, Warsawa, Not set

FutureMeds Targowek, Warsaw, Not set

Narodowy Instytut Geriatrii; Reumatologii i Rehabilitacji, Warszawa, Not set

Niepubliczny Zaklad Opieki Zdrowotnej Biogenes Sp. z o.o., Wroclaw, Not set

Dolnoslaski Szpital Specjalistyczny im. Tadeusza Marciniaka, Wroclaw, Not set

Instituto Portugues de Reumatologia, Lisboa, Not set

Centro Hospitalar Universitario Lisboa Norte E.P.E. (CHULN) - Hospital de Santa Maria, Lisboa, Not set

GCM Medical Group, PSC - Hato Rey Site-Hato Rey, San Juan, Not set

Local Institution - 0127, San Juan, Not set

ARENSIA Research Clinic Emergency County Hospital, Cluj-Napoca, Cluj

CMDTA Neomed SRL, Brasov, Not set

Arensia Research Clinic, Bucharest, Not set

Local Institution - 0104, Iasi, Not set

Hospital de Merida, Merida, Badajoz

Hospital Universitario Marques de Valdecilla, Santander, Cantabria

Hospital Universitario De Canarias - San Cristbal de La Laguna, La Laguna, Santa Cruz De Tenerife

Local Institution - 0112, A Coruna, Not set

Clinica GAIAS Santiago, Santiago De Compostela, Not set

Hospital Infantaluisa, Sevilla, Not set

Sahlgrenska University Hospital, Gotenburg, Not set

Karolinska University Hospital, Solna, Not set

Local Institution - 0066, Basel, Baden-Württemberg

Insel Gruppe AG, Bern, Not set

Kantonsspital St. Gallen, Southwest, Not set

Chang Gung Medical Foundation Kaohsiung Chang Gung Memorial Hospital, Kaohsiung City, Not set

China Medical University Hospital CMUH, Taichung, Not set

Local Institution - 0002, Taichung, Not set

National Taiwan University Hospital NTUH, Taipei City, Not set

Chang Gung Medical Foundation Linkou Chang Gung Memorial Hospital, Taoyuan City, Not set

Gazi University Hospital, Yenimahalle, Ankara

Hacettepe University School Of Medicine, Ankara, Not set

Akdeniz University Medical Faculty, Antalya, Not set

Local Institution - 0086, Istanbul, Not set

Istanbul University Cerrahpasa Medical School, Istanbul, Not set

Southampton General Hospital - University Hospital Southampton NHS Foundation Trust, Southampton, Hampshire

Local Institution - 0053, Newcastle Upon Tyne, Tyne And Wear

New Cross Hospital, Wolverhampton, West Midlands

University of Birmingham - Queen Elizabeth Hospital, Birmingham, Not set

Cannock Chase Hospital, Cannock, Not set

Conditions: Sjögren's Syndrome

Learn More ›

Evaluation of the Effects of a Nutritional Intervention of Ketogenic Medium-chain Triglycerides and B-vitamins on Cognitive Functioning in Older Adults With Mild Cognitive Impairment (COGNIKET-MCI)

NCT06347315

Recruiting

Evaluation of the Effects of a Nutritional Intervention of Ketogenic Medium-chain Triglycerides and B-vitamins on Cognitive Functioning in Older Adults With Mild Cognitive Impairment (COGNIKET-MCI)

Gender:

ALL

Ages:

60 years and above

Trial Updated:

08/11/2025

Locations: Stein Gerontological Institute Inc, Miami, Florida +29 locations

Stein Gerontological Institute Inc, Miami, Florida

University of Rochester, Rochester, New York

Hôpital Pierre Wertheimer, Bron, Not set

CHU de Montpellier - Hôpital Gui de Chauliac, Montpellier, Not set

CHU de Nantes - Hôpital Nord Laennec, Nantes, Not set

CHU de Toulouse - Gerontopole, Toulouse, Not set

Klinikum Bayreuth GmbH - Klinik Hohe Warte, Bayreuth, Not set

Studienzentrum für Neurologie und Psychiatrie, Böblingen, Not set

Neuro Centrum Science GmbH, Erbach, Not set

Universitaetsmedizin Ulm, Ulm, Not set

Foundation Institute G.Giglio, Cefalu, Not set

IRCCS Ospedale Policlinico San Martino, Genova, Not set

Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone", Palermo, Not set

AOU Policlinico Umberto I - Sapienza Università di Roma, Roma, Not set

Azienda Ospedaliera SantAndrea, Roma, Not set

Laboratory of Neuropsyichiatry, Fondazione Santa Lucia IRCCS, Roma, Not set

Policlinico Universitario Agostino Gemelli, Roma, Not set

AO Card. G. Panico, Tricase, Not set

Hospital Universitario del Vinalopó, Alicante, Not set

Fundaciò ACE, Barcelona, Not set

HGU Gregorio Marañón, Madrid, Not set

Unidad de Investigación Neurociencias Centro de Salud San Juan, Salamanca, Not set

Hospital Universitari General de Catalunya, Sant Cugat Del Vallès, Not set

Hospital Universitario Victoria Eugenia, Sevilla, Not set

Hospital Universitari i Politecnic La Fe, Valencia, Not set

Universitare Altersmedizin FELIX PLATTER, Basel, Not set

Spitalzentrum Centre Hospitalier Biel-Bienne AG (SZB), Biel, Not set

CHUV, Lausanne, Not set

Sussex Partnership NHS foundation Trust, Crowborough, Not set

Hampshire & Isle of Wight Healthcare NHS Foundation Trust, Southampton, Not set

Conditions: Mild Cognitive Impairment

Learn More ›

Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)

NCT06274801

Recruiting

This open-label extension study will evaluate the long-term safety, tolerability and efficacy of orally inhaled seralutinib in subjects who have completed a previous seralutinib study

Gender:

ALL

Ages:

Between 18 years and 75 years

Trial Updated:

08/11/2025

Locations: Valley Advanced Lung Diseases Institute, Fresno, California +75 locations

Valley Advanced Lung Diseases Institute, Fresno, California

Department of Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, California

UC Davis Health Medical Center, Sacramento, California

Stanford Healthcare, Stanford, California

Piedmont Physicians Pulmonary & Sleep Medicine of Buckhead, Atlanta, Georgia

The Emory Clinic, Atlanta, Georgia

Northside Hospital - Atlanta, Atlanta, Georgia

UI Health Hospital, Chicago, Illinois

University of Kansas Medical Center, Kansas City, Kansas

Norton Pulmonary Specialists, Louisville, Kentucky

University of Nebraska Medical Center, Omaha, Nebraska

University of New Mexico Health Sciences Center, Albuquerque, New Mexico

NYU Langone Health, New York, New York

UNC Hospitals, Chapel Hill, North Carolina

The Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania

UPMC Presbyterian Hospital, Pittsburgh, Pennsylvania

Houston Methodist Outpatient Center, Houston, Texas

Intermountain Medical Center, Murray, Utah

Inova Fairfax Medical Campus, Falls Church, Virginia

Pulmonary Associates of Richmond, Inc., Richmond, Virginia

Cardiologia Palermo, Buenos Aires, Not set

Instituto de Cardiologia de Corrientes Juana Francisca Cabral, Corrientes, Not set

Instuto de Investigacion Clinicas Quilmes, Quilmes, Not set

Instituto Medico Rio Cuarto, Río Cuarto, Not set

Hospital Provincial Dr. Jose Maria Cullen, Santa Fe, Not set

Wesley Research Institute, Auchenflower, Not set

St Vincent's Hospital (Melbourne), Fitzroy, Not set

Hopital Erasme, Anderlecht, Not set

Irmandade da Santa Casa de Misericórdia de Porto Alegre, Porto Alegre, Not set

Centro de Investigacion Clinica UC-CICUC, Santiago, Not set

Enroll SpA, Santiago, Not set

Institut klinicke a experimentalni mediciny Klinika kardiologie Ambulance plicni hypertenze, Praha, Not set

Všeobecná fakultní nemocnice v Praze ll. interní klinika kardiologie a angiologie VFN a 1.LF UK Centrum pro plicní hvpertenzi, Praha, Not set

Aarhus Universiteshospital, Aarhus, Not set

CHU Bicetre, Service de Pneumologie et Reanimation Respiratorie, Le Kremlin-Bicêtre, Not set

Centre Hospitalier REgional Universitaire de Lille Hopital Cardiologique - Institut Coeur Poumon Service de Cardiologie, Lille, Not set

CHU de Nice - Hopital Pasteur, Nice, Not set

CHU de Poitiers, Poitiers, Not set

Universitätsklinikum Dresden, Medizinische Klinik I / Pneumologisches Studiensekretariat, Dresden, Not set

Universitatsklinikum Giessen und Marburg GmbH Zentrum fur lnnere Medizin, Med. Klinik und Poliklinik II Studienambulanz fur Pulmonale Hypertonie, Gießen, Not set

Thoraxklinik Heidelberg gGmbH am Universitätsklinikum Heidelberg Zentrum für pulmonale Hypertonie, Heidelberg, Not set

Zentrum fur Pulmonale Hypertonie, Klinik Ill fur lnnere Medizin (Kardiologie, Pneumologie, lnternistische lntensivmedizin), Herzzentrum der Universitat zu Koln, Köln, Not set

Krankenhaus Neuwittelsbach, München, Not set

Klinikum Würzburg Mitte gGmbH Medizinische Klinik mit Schwerpunkt Pneumologie und Beatmungsmedizin, Würzburg, Not set

"Evangelismos" General Hospital of Athens, 1st Department of Clinical Care and Pulmonary Hypertension Clinic, Athens, Not set

ATTIKON University Hospital, 2nd Critical Care Department, Athens, Not set

Onassis Cardiac Surgery Center, Non-Invasive Cardiology Department, Kallithéa, Not set

AHEPA University General Hospital of Thessaloniki, 1st Cardiology Clinic, Thessaloníki, Not set

Lady Davis Carmel Medical Center, Haifa, Not set

IRCCS Azienda Ospedaliero Universitaria Di Bologna - Policlinico S. Orsola-Malpighi - UOC Cardiologia, Bologna, Not set

Azienda Ospedaliera Dei Colli - Ospedale Monaldi, Napoli, Not set

Fondazione IRCCS Policlinico San Matteo, Pavia, Not set

A.O.U. Policlinico Umberto I, Roma, Not set

University of Tokyo Hospital, Bunkyō-Ku, Not set

Nagoya University Hospital, Nagoya, Not set

National Cerebral and Cardiovascular Center, Suita, Not set

Samsung Medical Center, Seoul, Not set

Severance Hospital, Yonsei University Health System, Seoul, Not set

Pauls Stradins Clinical University Hospital, Riga, Not set

Hospital of Lithuanian University of Health Sciences Kauno klinikos, Kaunas, Not set

Unidad de Investigacion Clinica en Medicina, S.C., Monterrey, Not set

Erasmus MC, Rotterdam, Not set

Europejskie Centrum Zdrowia Otwock Sp.zo.o. Szpital im. Fryderyka Chopina Oddzial Kardiologiczny, Otwock, Not set

Unidade Local de Saude de Santo Antonio, E.P.E. Hospital de Santo Antonio, Porto, Not set

Institutul De Urgenta Pentru Boli Cardiovasculare Prof. Dr. C. C. Iliescu Cardiology 2, Bucharest, Not set

"Niculae Stancioiu" Emergency Heart Institute for Cardiovascular Diseases, Cardiology 1 Department, Cluj-Napoca, Not set

University Clinical Centre of Serbia, Cardiology Clinic, Belgrade, Not set

National Heart Centre Singapore, Singapore, Not set

National University Heart Centre, Singapore, Not set

Hospital Clinic I Provincial, Barcelona, Not set

Hospital Universitario 12 De Octubre, Madrid, Not set

Hospital Universitario Virgen del Rocio, Sevilla, Not set

Hospital Universitario de Toledo, Toledo, Not set

Royal Papworth Hospital NHS Foundation Trust, Cambridge, Not set

Golden Jubilee National Hospital, Clydebank, Not set

Hammersmith Hospital, London, Not set

Conditions: Pulmonary Arterial Hypertension

Learn More ›

Enasidenib for Patients With Clonal Cytopenia of Undetermined Significance and Mutations in IDH2A Decentralized Trial

NCT06240754

Recruiting

Study researchers think that a drug called enasidenib may help people with clonal cytopenia of undetermined significance (CCUS) because the drug blocks the mutated IDH2 protein, which may improve blood cell counts. The purpose of this study is to find out whether enasidenib is a safe and effective treatment for CCUS.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/11/2025

Locations: Washington University School of Medicine, Saint Louis, Missouri

Conditions: Clonal Cytopenia of Undetermined Significance, CCUS Clonal Cytopenia of Undetermined Significance

Learn More ›

Treatment of Cognitive Deficits in Multiple Sclerosis With High-Definition Transcranial Direct Current Stimulation

NCT05958381

Recruiting

The purpose of the study is to test whether low level electric stimulation, called transcranial Direct Current Stimulation (tDCS), on the part of the brain (i.e., presupplementary motor area) thought to aid in memory will improve verbal retrieval in multiple sclerosis patients. The primary outcome measures are neuropsychological assessments of verbal retrieval, and the secondary measures are neuropsychological assessments of other cognitive abilities and electroencephalography (EEG) measures. Ad... Read More

Gender:

ALL

Ages:

Between 18 years and 65 years

Trial Updated:

08/11/2025

Locations: The University of Texas at Dallas, Richardson, Texas

Conditions: Multiple Sclerosis, Relapsing-Remitting

Learn More ›

iLookOut Micro-learning to Improve Knowledge Retention

NCT06273618

Recruiting

This project investigates whether a multi-faceted strategy involving iLookOut's evidence-based Core Training plus an innovative follow-up Micro-Learning can promote knowledge retention and change behavior among early childhood professionals (ECPs) with regard to child abuse and its reporting. Additionally, this study will evaluate if non-ECPs experience similar improvements and retention of knowledge and changes in behavior as do ECPs.

Gender:

ALL

Ages:

Between 18 years and 100 years

Trial Updated:

08/11/2025

Locations: Penn State College of Medicine, Hershey, Pennsylvania

Conditions: Knowledge, Attitudes, Practice

Learn More ›

ALPINE: Maintenance Letrozole/Abemaciclib vs Pembrolizumab

NCT06366347

Recruiting

A standard treatment for endometrial cancer is chemotherapy and pembrolizumab together followed by pembrolizumab maintenance for two years. This treatment regimen has shown benefit in terms of delaying cancer progression in prior clinical trials, but the benefit of the pembrolizumab maintenance treatment and whether all participants need it is unclear. This research is being done on the maintenance portion of treatment to compare the efficacy between the combination of letrozole + abemaciclib an... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/11/2025

Locations: Beth Israel Deaconess Medical Center, Boston, Massachusetts +5 locations

Conditions: Endometrial Cancer, Recurrent Endometrial Cancer, TP53

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Safety and Effectiveness of Endoscopic Intestinal Re-Cellularization Therapy in Individuals With Type II Diabetes

NCT06267391

Recruiting

This study is designed to evaluate the safety and effectiveness of endoscopic intestinal re-cellularization therapy in individuals with type 2 diabetes (T2D) inadequately controlled on non-insulin glucose-lowering medications.

Gender:

ALL

Ages:

Between 22 years and 70 years

Trial Updated:

08/11/2025

Locations: University of Alabama, Birmingham, Alabama +44 locations

University of Alabama, Birmingham, Alabama

Central Alabama Research, Birmingham, Alabama

Velocity Clinical Research, Gardena, Gardena, California

Cedars-Sinai Medical Center, Los Angeles, California

UCLA, Los Angeles, California

Hoag Memorial Hospital Presbyterian - Digestive Health Institute, Newport Beach, California

Velocity Clinical Research, Panorama City, Panorama City, California

Velocity Clinical Research, Hallandale Beach, Hallandale Beach, Florida

Mayo Clinic, Jacksonville, Florida

Quantum Clinical Research, Miami Beach, Florida

Universal Axon Clinical Research LLC, Miami, Florida

University of Miami, Miami, Florida

West Orange Endocrinology, Ocoee, Florida

Advent Health, Orlando, Florida

Orlando Health, Orlando, Florida

Health Synergy Clinical Research, West Palm Beach, Florida

NorthShore University Health System, Evanston, Illinois

Heartland Medical Research, Inc., Clive, Iowa

Iowa Diabetes and Endocrinology Research Center, West Des Moines, Iowa

John Hopkins, Baltimore, Maryland

Mayo Clinic, Rochester, Minnesota

Cooper Health System, Camden, New Jersey

Robert Wood Johnson Medical School, New Brunswick, New Jersey

The Ohio State University- Wexner Medical Center, Columbus, Ohio

Velocity Clinical Research - Austin, Austin, Texas

Dell Medical School, Austin, Texas

IMA Clinical Research - Austin, Austin, Texas

The University of Texas Health Science Center at Houston, Bellaire, Texas

Velocity Clinical Research, Dallas, Dallas, Texas

Southwest Medical Center, Dallas, Texas

University of Texas Southwestern Medical School - William P. Clements Jr. University Hospital, Dallas, Texas

Epic Medical Research, DeSoto, Texas

Houston Methodist Research Institute, Houston, Texas

Juno Research, LLC, Houston, Texas

Texas Diabetes & Endocrinology, P.A., Round Rock, Texas

Diabetes & Glandular Disease Clinic, P.A., San Antonio, Texas

IMA Clinical Research - San Antonio, San Antonio, Texas

Mt. Olympus Medical Research, Sugar Land, Texas

Royal Prince Alfred Hospital, Camperdown, New South Wales

The BMI Clinic, Double Bay, New South Wales

Royal North Shore Hospital, Saint Leonards, New South Wales

Eastern Health - Box Hill Hospital, Box Hill, Victoria

St Vincent's Hospital Melbourne, Fitzroy, Victoria

Austin Health, Heidelberg, Victoria

Baker Heart and Diabetes Institute, Melbourne, Victoria

Conditions: Type 2 Diabetes Mellitus, Type2diabetes, Diabetes Mellitus, Type 2, Diabetes, Type 2 Diabetes

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Contrast Echocardiography During Exercise to Assess Pulmonary Blood Volume

NCT06195059

Recruiting

The purpose of this study is to evaluate whether pulmonary blood volume (PBV) derived from contrast echocardiography can serve as a non-invasive surrogate for invasive pulmonary artery wedge pressure (PAWP) during exercise. Also, to compare changes in PBV with exercise in patients with and without heart failure and pulmonary vascular disease.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/11/2025

Locations: Mayo Clinic in Rochester, Rochester, Minnesota

Conditions: Heart Failure, Pulmonary Vascular Disease

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A Clinical Trial of Study Medicine (Marstacimab) in Pediatric Patients With Hemophilia A or Hemophilia B

NCT05611801

Recruiting

The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called marstacimab) for the potential treatment of hemophilia in pediatric patients. This study will enroll pediatric participants from ages 1 to 17 years in a sequential manner. The study will open enrollment to adolescent participants aged 12 to 17 years first. Then children aged 6 to 11 years will be permitted to enroll. Lastly, children aged 1 to 5 years will be permitted to enroll. This study will enroll participants who: * have severe Hemophilia A or moderately severe to severe Hemophilia B (with or without inhibitors) * have accurate historical records documenting all factor VIII, factor IX, or bypass agent infusions and hemophilia bleed events for at least 1 year prior to entering the study * if a non-inhibitor patient, must be on a stable routine prophylaxis regimen with factor VIII or factor IX replacement products for at least 12 months prior to study entry * if an inhibitor patient, must be on an on-demand bypass treatment regimen during the 12 months prior to study entry All participants in this study will receive marstacimab to use prophylactically. Marstacimab will be given once a week as a subcutaneous (under the skin) shot. The first dose of marstacimab will be given at the study site by the study site staff. During the 12-month treatment period, weekly doses of marstacimab can be given at home, or if preferred, the doses may be given by the study site staff. To help us determine if the study medicine is safe and effective, we will compare participant experiences when they are taking the study medicine to a historical period when they were not. Researchers want to see if the study medicine works to prevent the bleeding episodes commonly experienced by patients with Hemophilia. Participants will be in this study for about 14 months (approximately 1 month in a Screening period, 12 months receiving treatment, and 1 month in a follow-up period) during which they will visit the study site at least 10 times. If preferred, and if local regulations allow it, 2 of the study visits can be completed at the participant's home instead of at the study site. There will also be 6 scheduled telephone calls approximately every 2 months. Read Less

Gender:

MALE

Ages:

Between 1 year and 17 years

Trial Updated:

08/11/2025

Locations: Intermountain - Primary Children's Hospital, Salt Lake City, Utah +59 locations

Intermountain - Primary Children's Hospital, Salt Lake City, Utah

Arbesu Hematología, Mendoza, Not set

Sydney Children's Hospital, Randwick, New South Wales

Royal Children's Hospital, Melbourne, Victoria

Medizinische Universität Wien, Vienna, Wien

HEMOES, Vitoria, Espírito Santo

Stollery Children's Hospital, Edmonton, Alberta

Hamilton Health Sciences - McMaster University Medical Centre, Hamilton, Ontario/canada

Beijing Children's hospital, Capital Medical University, Beijing, Beijing

Southern Medical University Nanfang Hospital, Guangzhou, Guangdong

The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou

Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei

Tongji Hospital of Tongji Medical College of HUST/Pediatric Hematology Department Pharmacy, Wuhan, Hubei

Jiangxi Provincial People's Hospital, Nanchang, Jiangxi

Institute of hematology&blood disease hospital, Tianjin, Tianjin

Detska nemocnice FN Brno, Brno, Brno-město

Rigshospitalet, Copenhagen, Hovedstaden

Aarhus Universitetshospital, Skejby, Aarhus, Midtjylland

Hôpital Universitaire Necker Enfants Malades, Paris, Not set

Charité Campus Virchow-Klinikum, Berlin, Not set

Nirmal Hospital Pvt Ltd., Surat, Gujarat

K.J. Somaiya Hospital, Mumbai, Maharashtra

Nil Ratan Sircar Medical College and Hospital, Kolkata, WEST Bengal

Sheba Medical Center, Ramat Gan, Hamerkaz

IRCCS Istituto Giannina Gaslini, Genova, Liguria

Istituto Clinico Humanitas, Rozzano, Milano

Ospedale Pediatrico Bambino Gesù IRCCS, Rome, Roma

Azienda Ospedaliero Universitaria di Parma, Parma, Not set

Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino, Torino, Not set

Hyogo prefectural Kobe Children's Hospital, Kobe, Hyogo

Nagano Children's Hospital, Azumino, Nagano

Nara Medical University Hospital, Kashihara, Nara

Saitama Prefectural Children's Medical Center, Saitama-shi, Saitama

Saga University Hospital, Saga, Not set

Severance Hospital, Yonsei University Health System, Seoul, Seoul-teukbyeolsi [seoul]

Kyung Hee University Hospital at Gangdong, Seoul, Seoul-teukbyeolsi [seoul]

Kyungpook National University Hospital, Daegu, Taegu-kwangyǒkshi

Arké SMO S.A de C.V, Veracruz, Not set

King Fahad Specialist Hospital - Dammam, Dammam, ASH Sharqīyah

King Faisal Specialist Hospital & Research Center, An Narjis, Not set

Detska fakultna nemocnica Kosice, Kosice, Not set

Univerzitna nemocnica Martin, Martin, Not set

Worthwhile Clinical Trials, Benoni, Gauteng

Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, Gauteng

Hospital Universitario La Paz, Madrid, Not set

Hospital Universitario Miguel Servet, Zaragoza, Not set

Changhua Christian Hospital, Changhua County, Changhua

Taichung Veterans General Hospital, Taichung, Not set

National Taiwan University Hospital, Taipei, Not set

Istanbul Universitesi Istanbul Tıp Fakultesi Hastanesi, İstanbul, İ̇stanbul

Ege Universitesi Hastanesi, Izmir, İ̇zmir

Erciyes University, Talas, Kayseri

Acibadem Adana Hospital, Adana, Not set

Gazi University Health Research and Application Center Gazi Hospital, Ankara, Not set

Erciyes Universitesi Tıp Fakultesi Hastaneleri, Kayseri, Not set

Ondokuz Mayıs Universitesi, Samsun, Not set

Royal Victoria Infirmary, Newcastle upon Tyne, England

Birmingham Children's Hospital, Birmingham, Not set

Evelina London Children's Hospital, London, Not set

Royal Manchester Children's Hospital, Manchester, Not set

Conditions: Hemophilia A, Hemophilia B

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Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease

NCT06332534

Recruiting

Crohn's disease (CD) is a long-lasting disease that causes severe inflammation (redness, swelling), in the digestive tract, most often affecting the bowels. It can cause many different symptoms including abdominal pain, diarrhea, tiredness, and weight loss. This study will assess how safe and effective oral Upadacitinib is in treating moderately to severely active Crohn's Disease in pediatric participants aged 2 to 18 years old who have had inadequate response, loss of response, intolerance, or medical contraindications to corticosteroids, immunosuppressants, and/or biologic therapy. Upadacitinib (RINVOQ) is a drug approved in adults for moderate- to severely active CD and is being developed for moderate- to severely active CD in pediatric participants. This study is conducted in 2 periods: Period 1 is comprised of two phases: a 12-week open-label induction phase which means that the study doctor and participants know that participants will receive UPA Dose-A (or the adult equivalent based on body weight) followed by a 52-week double-blind maintenance phase meaning that neither the participants nor the study doctors will know which dose of upadacitinib will be given(UPA Dose B or Dose C). Period 2 is a 156-week open-label extension of Period 1. Approximately 110 pediatric participants with moderate to severely active CD will be enrolled at approximately 92 sites worldwide. Participants will receive upadacitinib oral tablets once daily or oral solution twice daily at approximately the same time each day, with or without food. Participants will have a safety follow up for 30 days after discontinuation from any time point within the study. There may be higher treatment burden for participants in this trial compared to their standard of care (due to study procedures). Participants will attend regular (weekly, monthly) visits during the study at a hospital or clinic. The effect of the treatment will be checked by medical assessments, blood tests, checking for side effects and completing questionnaires. Read Less

Gender:

ALL

Ages:

Between 2 years and 17 years

Trial Updated:

08/11/2025

Locations: UCSF Benioff Children's Hospital - Oakland /ID# 262217, Oakland, California +77 locations

UCSF Benioff Children's Hospital - Oakland /ID# 262217, Oakland, California

Children's Hospital Colorado - Aurora /ID# 262207, Aurora, Colorado

Connecticut Children's Medical Center - Hartford /ID# 262256, Hartford, Connecticut

OSF St. Francis Medical Center /ID# 262192, Peoria, Illinois

Indiana University Health Riley Hospital for Children /ID# 262215, Indianapolis, Indiana

MNGI Digestive Health, P. A. /ID# 262204, Minneapolis, Minnesota

Icahn School of Medicine at Mount Sinai /ID# 262216, New York, New York

Univ NC Chapel Hill /ID# 262198, Chapel Hill, North Carolina

UH Cleveland Medical Center /ID# 262188, Cleveland, Ohio

Children's Hospital of Philadelphia - Main /ID# 262197, Philadelphia, Pennsylvania

Sydney Children's Hospital /ID# 262352, Randwick, New South Wales

Children's Hospital at Westmead /ID# 262350, Westmead, New South Wales

Queensland Children's Hospital /ID# 262351, South Brisbane, Queensland

Monash Health - Monash Medical Centre /ID# 262878, Clayton, Victoria

Perth Children'S Hospital /ID# 272905, Perth, Western Australia

Uza /Id# 261745, Edegem, Antwerpen

Cliniques Universitaires UCL Saint-Luc /ID# 261741, Bruxelles, Bruxelles-Capitale

Universitair Ziekenhuis Leuven /ID# 261740, Leuven, Vlaams-Brabant

Hospital Universite Enfants Reine Fabiola /ID# 261744, Bruxelles, Not set

CHR de la Citadelle /ID# 261749, Liege, Not set

UCL Namur University Hospital, Site Sainte-Elisabeth /ID# 261750, Namur, Not set

Galileo Medical Research Ltda /ID# 262602, Juiz de Fora, Minas Gerais

Hospital Pequeno Príncipe /ID# 262600, Curitiba, Parana

Irmandade da Santa Casa de Misericordia de Porto Alegre /ID# 262601, Porto Alegre, Rio Grande Do Sul

Hospital Sírio Libanês /ID# 262670, São Paulo, Sao Paulo

Rocco & Nazato Servicos Medicos /ID# 262485, São Paulo, Sao Paulo

UMHAT Sveti Georgi /ID# 262590, Plovdiv, Not set

Specialized Hospital For Active Treatment Of Children Diseases Prof. Ivan Mitev /ID# 262589, Sofiya, Not set

Beijing Children's Hospital /ID# 262258, Beijing, Beijing

Guangzhou Medical University Affiliated Women and Children's Medical Center /ID# 262596, Guangzhou, Guangdong

The Sixth Affiliated Hospital of Sun Yat-sen University /ID# 272807, Guangzhou, Guangdong

Henan Children's Hospital Zhengzhou Children's Hospital /ID# 262300, Zhengzhou, Henan

Hunan Children's Hospital /ID# 262512, Changsha, Hunan

Jiangxi Provincial Children's Hospital /ID# 262295, Nanchang, Jiangxi

Shengjing Hospital of China Medical University /ID# 262301, Shenyang, Liaoning

Children's Hospital of Shanghai /ID# 262356, Shanghai, Shanghai

Ruijin Hospital, Shanghai Jiaotong University School of Medicine /ID# 262502, Shanghai, Shanghai

The Children's Hospital of Zhejiang University School of Medicine /ID# 262337, Hangzhou, Zhejiang

CHU de CAEN - Hopital de la Cote de Nacre /ID# 262311, Caen, Calvados

Hospices Civils de Lyon - Hôpital Femme Mère Enfant /ID# 263422, Bron CEDEX, Rhone

Hopitaux de Paris (AP-HP) - Hopital Robert Debre - CHU /ID# 262308, Paris, Not set

Agia Sofia Hospital /ID# 261792, Athens, Attiki

General Hospital of Chest Diseases of Athens SOTIRIA /ID# 261790, Athens, Attiki

University General Hospital of Heraklion PA.G.N.I /ID# 261791, Heraklion, Kriti

Fondazione di Religione e di Culto Casa Sollievo della Sofferenza /ID# 262384, San Giovanni Rotondo, Foggia

Ospedale Pediatrico Bambino Gesù /ID# 262379, Rome, Roma

Azienda Ospedaliera Universitaria Gaetano Martino /ID# 262380, Messina, Not set

Tsujinaka Hospital - Kashiwanoha /ID# 262454, Kashiwa-shi, Chiba

Kurume University Hospital /ID# 262455, Kurume-shi, Fukuoka

Miyagi Children's Hospital /ID# 262459, Sendai-shi, Miyagi

Osaka Women's and Children's Hospital /ID# 262549, Izumi-Shi, Osaka

Saga University Hospital /ID# 262753, Saga-shi, Saga

Saitama Children's Medical Center /ID# 262461, Saitama-shi, Saitama

Institute of Science Tokyo Hospital /ID# 262510, Bunkyo-ku, Tokyo

Tokyo Metropolitan Children's Medical Center /ID# 262550, Fuchu-shi, Tokyo

National Center For Child Health And Development /ID# 262456, Setagaya, Tokyo

Toyama Prefectural Central Hospital /ID# 262739, Toyama-shi, Toyama

Seoul National University Hospital /ID# 262324, Seoul, Seoul Teugbyeolsi

Yonsei University Health System Severance Hospital /ID# 262721, Seoul, Seoul Teugbyeolsi

Samsung Medical Center /ID# 262323, Seoul, Seoul Teugbyeolsi

Christchurch Hospital. /ID# 262577, Christchurch, Canterbury

Starship Child Health /ID# 262576, Auckland, Not set

Gastromed Sp. z o.o /ID# 262367, Torun, Kujawsko-pomorskie

Instytut Pomnik - Centrum Zdrowia Dziecka /ID# 262366, Warsaw, Mazowieckie

Clinical Research Investigator Group, LLC /ID# 262357, Bayamon, Not set

Puerto Rico Health Institute /ID# 262358, Dorado, Not set

Hospital Arquitecto Marcide - Complejo Hospitalario Universitario de Ferrol /ID# 262226, Ferrol, A Coruna

Hospital Sant Joan de Deu /ID# 262599, Esplugues de Llobregat, Barcelona

Hospital Regional Universitario de Malaga /ID# 262228, Malaga, Not set

Hospital Universitario Virgen del Rocio /ID# 262712, Sevilla, Not set

Hospital Clinico Universitario Lozano Blesa /ID# 262227, Zaragoza, Not set

National Taiwan University Hospital /ID# 261695, Taipei City, Taipei

Linkou Chang Gung Memorial Hospital /ID# 261696, Taoyuan City, Not set

Addenbrooke's Hospital /ID# 262707, Cambridge, Cambridgeshire

Sheffield Children's Hospital NHS Foundation Trust /ID# 261832, Sheffield, England

Disc_Barts Health NHS Trust - The Royal London Hospital /ID# 262811, London, Greater London

Norfolk and Norwich University Hospitals NHS Foundation Trust /ID# 262778, Norwich, Norfolk

Royal Hospital for Children and Young People /ID# 262388, Edinburgh, Not set

Conditions: Crohn's Disease

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ALS20-101 Lentiviral Gene Therapy for Beta Thalassemia

NCT06364774

Recruiting

The main goal of this study is to find out if the blood disorder called transfusion-dependent beta thalassemia can be safely treated by modifying blood stem cells. This is done by collecting blood stem cells from the subject, modifying those cells, adding a healthy beta globin gene, and then giving them back to the subject. It is hoped that these modified cells will decrease the need for blood transfusions. The gene modified blood stem cells are called CHOP-ALS20 ("study drug"). This experimenta... Read More

Gender:

ALL

Ages:

Between 18 years and 35 years

Trial Updated:

08/11/2025

Locations: Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

Conditions: Beta-Thalassemia

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