Building Experience for Treating Trauma and Enhancing Resilience (BETTER)
NCT05330442
Recruiting
Posttraumatic stress disorder (PTSD) is a significant problem among underserved populations who receive care in community health centers. Several evidence-based psychotherapies for PTSD are not practical given the time and resources required for these approaches. This research will examine whether Written Exposure Therapy (WET), a brief and well-tolerated therapy approach, delivered within collaborative primary care is effective and can be implemented successfully within a collaborative care (CC... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: Oak Orchard Health Center (Albion), Albion, New York +9 locations
Conditions: PTSD
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A Study of Tebapivat (AG-946) in Participants With Anemia Due to Lower-Risk Myelodysplastic Syndromes (LR-MDS)
NCT05490446
Recruiting
This purpose of this study is to establish proof of concept of tebapivat in participants with LR-MDS in Phase 2a and to evaluate the effect of tebapivat on transfusion independence (TI) in participants with LR-MDS in phase 2b.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: Innovative Clinical Research Institute Whittier, Lakewood, California +44 locations
Conditions: Myelodysplastic Syndromes
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Engage & Connect: A Psychotherapy for Postpartum Depression
NCT05585164
Recruiting
This randomized controlled trial compares a novel psychotherapy, Engage \& Connect, with a Symptom Review and Psychoeducation intervention, tailored to reduce postpartum depression. The study includes 9-weeks interventions, delivered remotely. It will examine changes in social isolation, processing of social rewards and depression severity over 9 weeks of treatment.
Gender:
FEMALE
Ages:
All
Trial Updated:
04/23/2025
Locations: Weill Cornell Medicine, New York, New York
Conditions: Postpartum Depression
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Evaluation of TENEX for Greater Trochanteric Pain Syndrome (GTPS)
NCT05710627
Recruiting
The objective of this study is to evaluate how an ultrasound-guided percutaneous procedure, TENEX, can help people with chronic hip pain resulting from a condition called Greater Trochanteric Pain Syndrome (GTPS) and to characterize the efficacy of percutaneous tenotomy (PUT) using TENEX®, a device used for the treatment of various tendinopathies. In this study an ultrasound (US) is performed to guide the partial release of gluteus medius and minimus and Iliotibial band tendons in patients diagn... Read More
Gender:
ALL
Ages:
Between 30 years and 90 years
Trial Updated:
04/23/2025
Locations: Montefiore Medical Center, Bronx, New York
Conditions: Greater Trochanteric Pain Syndrome
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Functional Dyspepsia Treatment Using Virtual Reality
NCT05836597
Recruiting
The purpose of this study is to evaluate the effectiveness of using virtual reality to treat gastrointestinal symptoms related to functional dyspepsia.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
04/23/2025
Locations: Mayo Clinic in Florida, Jacksonville, Florida
Conditions: Functional Dyspepsia
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A Study Following Women in Menopause Treated With a Non-hormonal Therapy for Hot Flashes and Night Sweats
NCT06049797
Recruiting
Hot flashes and night sweats (also known as vasomotor symptoms or VMS) are the most common symptoms which bother women in menopause. This study will follow women going through menopause who have hot flashes and night sweats that cause them bother. They will be starting a non-hormonal therapy prescribed by their healthcare provider (HCP) to treat these symptoms. The women will visit their HCP's office, research center, or both. They will receive prescriptions for the non-hormonal therapy from the... Read More
Gender:
FEMALE
Ages:
Between 40 years and 75 years
Trial Updated:
04/23/2025
Locations: Alabama Clinical Therapeutics, Birmingham, Alabama +60 locations
Conditions: Hot Flashes
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Phase 2 Trial of Obinutuzumab and CC-99282 for Patients With Previously Untreated High Tumor Burden Follicular Lymphoma
NCT06108232
Recruiting
To learn if obinutuzumab in combination with CC-99282 can help to control previously untreated, high tumor burden FL
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Follicular Lymphoma, Tumor
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Four Pillars of Defense: A Whole Health Approach to the Military
NCT06205186
Recruiting
The overall objectives of this study are to better define the construct of psychological resilience in the military, to identify potential modifiable risk factors and trainable skills of psychological resilience in Soldiers, and provide a scalable, integrated physical and mental optimization training app to be integrated into relevant systems. The proposed work would be a first step in identifying predictive risk factors that can be modified to increase the future resilience of Soldiers. With th... Read More
Gender:
ALL
Ages:
21 years and above
Trial Updated:
04/23/2025
Locations: Pennington Biomedical Research Center, Baton Rouge, Louisiana
Conditions: Health Behavior
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A Study of the Cobas® Liat CT/NG/MG Test Versus Current Standard Practice for Managing Participants at Increased Risk of Sexually Transmitted Infections
NCT06369220
Recruiting
This study is designed to assess the comparative clinical utility of the point of care cobas® liat CT/NG/MG to current standard practices in the diagnosis and treatment of urogenital infections with Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), and Mycoplasma genitalium (MG).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: San Francisco City Clinic, San Francisco, California +3 locations
Conditions: Chlamydia Trachomatis Infection, Neisseria Gonorrhoeae Infection, Mycoplasma Genitalium Infection
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A Study to Investigate the Efficacy and Safety of Anifrolumab Administered as Subcutaneous Injection and Added to Standard of Care Compared With Placebo Added to Standard of Care in Adult Participants With Idiopathic Inflammatory Myopathies (Polymyositis and Dermatomyositis)
NCT06455449
Recruiting
The purpose of this multicenter, randomized, placebo-controlled and double-blind study is to evaluate the efficacy and safety of subcutaneous anifrolumab compared with placebo on the overall disease activity in participants with moderate to severe Idiopathic Inflammatory Myopathies (IIM) \[polymyositis (PM) or dermatomyositis (DM)\] while receiving standard of care (SoC) treatment.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
04/23/2025
Locations: Research Site, Irvine, California +191 locations
Conditions: Polymyositis, Dermatomyositis
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A Research Study Comparing How Well Different Doses of the Medicine NNC0487-0111 Lower Blood Sugar in People With Type 2 Diabetes
NCT06542874
Recruiting
The study will look at how well different doses of a new medicine called NNC0487-0111 help lower the blood sugar and body weight in people with type 2 diabetes. NNC0487-0111 is a new medicine which cannot be prescribed by doctors but has previously been tested in humans. Participants will either get NNC0487-0111, which is given as tablets or as injections, or placebo. Which treatment the participant get is decided by chance.The study will last for about 43 weeks.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
04/23/2025
Locations: Southern Cal Clinical Research, Santa Ana, California +178 locations
Conditions: Type 2 Diabetes (T2D)
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Ear-Seizure Detection (EarSD) Study
NCT06598189
Recruiting
The proposed study is an investigator-initiated study that aims to measure the accuracy of a wearable seizure detection and prediction device (Ear-Seizure Detection Device (EarSD)) by simultaneous recording with conventional video-EEG (Electroencephalogram) on patients with epileptic seizures in the Epilepsy Monitoring Unit of the hospital.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: Ummmc-Memorial Campus, Worcester, Massachusetts +1 locations
Conditions: Seizures, Epilepsy
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