Duloxetine and Neurofeedback Training for the Treatment of Chemotherapy Induced Peripheral Neuropathy
Recruiting
This phase II trial investigates how well duloxetine and neurofeedback training work in treating patients with chemotherapy induced peripheral neuropathy. Duloxetine is a type of serotonin and norepinephrine reuptake inhibitor that increases the amount of certain chemicals in the brain that help relieve depression and peripheral neuropathy. Neurofeedback training is a type of therapy that uses an electroencephalograph (EEG) and a computer software program to measure brain wave activity and may h... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/28/2025
Locations: Harris Health System (LBJ), Houston, Texas +1 locations
Conditions: Chemotherapy-Induced Peripheral Neuropathy, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Evaluation of Portal Vein Stenting in Patients With Portal Vein Stenosis and Gastrointestinal Cancers
Recruiting
This study collects information about the safety and effect of portal vein stenting in gastrointestinal cancer patients with portal vein stenosis. This study may help researchers learn how long the portal vein stays open and free from blockage and the effects of portal vein stenting on patients' overall well-being.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/28/2025
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Malignant Digestive System Neoplasm
Secukinumab Open Label Roll-over Extension Protocol
Recruiting
The purpose of this study is to assess long term safety in participants who have completed a Novartis trial with secukinumab, have been judged by the investigator to benefit from continued treatment with secukinumab, and are unable to obtain the marketed secukinumab formulation.
Gender:
ALL
Ages:
Between 6 years and 100 years
Trial Updated:
07/28/2025
Locations: Providence Medical Foundation, Fullerton, California +166 locations
Conditions: Autoimmunity, Inflammation
Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders
Recruiting
This is a single-arm study to investigate 1-year treatment related mortality (TRM) in patients with life threatening non-malignant and malignant hematologic disorders who do not have a matched related donor for allogeneic transplantation.
Gender:
ALL
Ages:
21 years and below
Trial Updated:
07/28/2025
Locations: Memorial Sloan Kettering Cancer Center, New York, New York
Conditions: MDS, AML, ALL, MPD Withou Myelofibrosis, NHL or HL, Inherited Metabolic Disorders, Hemoglobinopathies, Bone Marrow Failure, HLH
BAFFR Targeting CAR-T Cells for the Treatment of Relapsed or Refractory B-cell ALL
Recruiting
A Phase 1 Study Evaluating BAFFR-targeting CAR T Cells for Patients with Relapsed or Refractory B-cell Acute Lymphoblastic Leukemia
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/28/2025
Locations: City of Hope Medical Center, Duarte, California
Conditions: Relapsed or Refractory B-cell Acute Lymphoblastic Leukemia
Safety and Efficacy of ActiGraft Treatment in Wound Care in Medical Centers
Recruiting
Multicenter observational study to explore the efficacy of ActiGraft in the treatment of exuding cutaneous wounds in real-life usage.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/28/2025
Locations: Wound Care Experts, Las Vegas, Nevada
Conditions: Cutaneous Wounds
COVID-19 Vaccines International Pregnancy Exposure Registry
Recruiting
The objective of the COVID-19 Vaccines International Pregnancy Exposure Registry (C-VIPER) is to evaluate obstetric, neonatal, and infant outcomes among women vaccinated during pregnancy with a COVID-19 vaccine. Specifically, the C-VIPER will estimate the risk of obstetric outcomes (spontaneous abortion, antenatal bleeding, gestational diabetes, gestational hypertension, intrauterine growth restriction, postpartum hemorrhage, fetal distress, uterine rupture, placenta previa, chorioamnionitis, C... Read More
Gender:
FEMALE
Ages:
Between 18 years and 50 years
Trial Updated:
07/28/2025
Locations: Pregistry, Los Angeles, California
Conditions: Covid19
Trifecta-Heart cfDNA-MMDx Study
Recruiting
Demonstrate the relationship between DD-cfDNA levels and HLA antibodies in blood transplant recipient and the Molecular Microscope® (MMDx) Diagnostic System results in indication and protocol biopsies from heart transplants.
Gender:
ALL
Ages:
All
Trial Updated:
07/28/2025
Locations: Baptist Health Institute for Research and Innovation, Little Rock, Arkansas +11 locations
Conditions: Heart Transplant Rejection
Corneal Crosslinking for Treatment of Corneal Neovascularization
Recruiting
The study objective is to assess safety and efficacy of photo-activation of riboflavin for treatment of corneal neovascularization with or without concomitant inflammation and/or infection.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/28/2025
Locations: Price Vision Group, Indianapolis, Indiana
Conditions: Corneal Neovascularization
An Investigational Scan (Intravoxel Incoherent Motion Diffusion Weighted Imaging) for the Evaluation of Colorectal Cancer Liver Metastases Treatment Response
Recruiting
This trial evaluates the treatment response of colorectal cancer that has spread to the liver (liver metastases) using intravoxel incoherent motion diffusion weighted imaging (IVIM DWI). IVIM DWI is new kind of imaging scan that may help measure changes in disease before and after chemotherapy in patients with colorectal liver metastases.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/28/2025
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Metastatic Colorectal Carcinoma, Metastatic Malignant Neoplasm in the Liver, Resectable Colorectal Carcinoma, Stage IV Colorectal Cancer AJCC v8, Stage IVA Colorectal Cancer AJCC v8, Stage IVB Colorectal Cancer AJCC v8, Stage IVC Colorectal Cancer AJCC v8
Efficacy of a Self-advocacy Serious Game Intervention
Recruiting
Individuals with cancer must overcome multiple, ongoing challenges ("self-advocate") related to their cancer experience to receive patient-centered care. Women with metastatic cancer often face significant challenges managing their quality of life concerns and cancer- and treatment-related symptoms. If they do not self-advocate to manage these concerns, they risk having poor quality of life, high symptom burden, and care that is not patient-centered. Serious games (video games that teach) are ef... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/28/2025
Locations: UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania
Conditions: Self-Management, Quality of Life
An Imaging Technology, Contrast-Enhanced Mammography, in Predicting Breast Cancer
Recruiting
This clinical trial examines a new imaging technology, contrast-enhanced mammography, in predicting breast cancer. Contrast-enhanced mammography is similar to standard mammography, but it includes an intravenous (by vein) injection of iodine-based contrast, which makes tissue and blood vessels more visible in scans. Contrast-enhanced mammography may work better in detecting cancer in the breast that is not seen on other imaging tests and may help doctors find the most suspicious areas of the bre... Read More
Gender:
ALL
Ages:
Between 25 years and 85 years
Trial Updated:
07/28/2025
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Breast Carcinoma