The Sweet Dreams Study - Accuracy of Sleep Trackers in Children
NCT06787378
Recruiting
The study aims to evaluate the accuracy of sleep trackers in children aged 2 to less than 18 years. Children undergoing polysomnography, the gold standard for assessing sleep quality and duration, at Arkansas Children's Hospital may be eligible to participate. Participants will be asked to wear sleep trackers on the day of their sleep test. The data collected from the sleep trackers will be compared with the polysomnography results to determine the devices' accuracy.
Gender:
ALL
Ages:
Between 2 years and 17 years
Trial Updated:
03/31/2025
Locations: Arkansas Children's Hospital, Little Rock, Arkansas +1 locations
Conditions: Sleep
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The Impact of Low Glycemic Index Nutritional Shake on Glucose Regulation in Overweight and Obese Adults
NCT06856460
Recruiting
Low glycemic index nutritional shakes have clinically shown to improve post-prandial glycemic responses in acute laboratory control studies. However, there is limited information on how replacing meals with low-glycemic index shake could impact glucose regulation in free-living adults consuming their own diets. The present study aims to examine the impact of adding the SP Glucose-Assist shake to the breakfast of non-diabetic overweight and obese adults. Subjects: 40 non-diabetic adults aged 2... Read More
Gender:
ALL
Ages:
Between 25 years and 65 years
Trial Updated:
03/31/2025
Locations: Arizona State University 850 PBC, Phoenix, Arizona
Conditions: Hyperglycemia, Obesity Prevention
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Light Therapy Intervention in Individuals With Parkinson's Disease
NCT06916260
Recruiting
The study looks to investigate the effects that light therapy delivered to the frontal cortex could have on Parkinson's disease related symptoms ( both cognitive and motor). The therapy is a non invasive technique that deliverers low level wavelength light to the front part of the head for 12 minutes. for this study the therapy will be done 3 times a week for 6 weeks. To measure the potential effects on the therapy in Parkinson symptoms, we will do a set of cognitive and motor test before and af... Read More
Gender:
ALL
Ages:
Between 50 years and 80 years
Trial Updated:
03/31/2025
Locations: University of Delaware STAR Tower, Newark, Delaware
Conditions: Parkinson Disease
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Studies of Neuregulin/ERBB Signaling in Human Heart
NCT02820233
Recruiting
This study examines the role of the epidermal growth factor (EGF) receptor family and the EGF family of ligands in the regulation of non-myocytes isolated from the human heart.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/31/2025
Locations: Maine Medical Center, Portland, Maine
Conditions: Heart Disease, Vascular Disease, Heart Failure
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Marker Driven Selection of Patients for Prostate Biopsy and Management
NCT04240327
Recruiting
The purpose of this research study is to determine if the interpretation of multiparametric MRI (mpMRI) with an algorithm called habitat risk score (HRS) in combination with a panel of blood and urine biomarkers is more effective at detecting prostate cancer than standard of care interpretation of mpMRI with the Prostate Imaging Reporting and Data System (PIRADS).
Gender:
MALE
Ages:
Between 40 years and 85 years
Trial Updated:
03/31/2025
Locations: University of Miami, Miami, Florida
Conditions: PSA, Elevated PSA, Prostate Cancer
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Comparing Carbon Ion Therapy, Surgery, and Proton Therapy for Management of Pelvic Sarcomas Involving the Bone
NCT05033288
Recruiting
This study compares carbon ion therapy, surgery, and proton therapy to determine if one has better disease control and fewer side effects. There are three types of radiation treatment used for pelvic bone sarcomas: surgery with or without photon/proton therapy, proton therapy alone, and carbon ion therapy alone. The purpose of this study is to compare quality of life among patients treated for pelvic bone sarcomas across the world, and to determine if carbon ion therapy improves quality of life... Read More
Gender:
ALL
Ages:
15 years and above
Trial Updated:
03/31/2025
Locations: Mayo Clinic in Arizona, Scottsdale, Arizona +2 locations
Conditions: Bone Sarcoma, Chondrosarcoma, Chordoma, Ewing Sarcoma of Bone, Pelvic Rhabdomyosarcoma
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Cannabis, HIV and Mental Processing Systems
NCT05430490
Recruiting
This study employs novel methods to identify key determinants and consequences of concurrent HIV infection and regular cannabis use. This study will acquire extensive phenotype data from peripheral and brain markers of immune activation, brain structure, and neuropsychological performance (NP) in persons living with HIV (PLWH) receiving combination anti-retroviral therapy (cART) (80 regular cannabis users and 80 non-users) and HIV uninfected (HIV-) controls (80 regular cannabis users and 80 non-... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
03/31/2025
Locations: Washington University School of Medicine, Saint Louis, Missouri +1 locations
Conditions: HIV Infections, Cannabis
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A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers
NCT05544929
Recruiting
The purpose of this study is to characterize the safety and tolerability of KFA115 and KFA115 in combination with pembrolizumab in patients with select advanced cancers, and to identify the maximum tolerated dose and/or recommended dose.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
03/31/2025
Locations: Massachusetts General Hospital ., Boston, Massachusetts +15 locations
Conditions: Carcinoma, Non-Small-Cell Lung, Cutaneous Melanoma, Carcinoma, Renal Cell, Carcinoma, Ovarian Epithelial, Nasopharyngeal Carcinoma, Carcinoma, Thymic, Anal Cancer, Mesothelioma, Esophagogastric Cancer, High Microsatellite Instability Colorectal Carcinoma, Squamous Cell Carcinoma of Head and Neck, Triple Negative Breast Neoplasms
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Busulfan Sample Collection Study
NCT05711732
Recruiting
Busulfan (Busulfex®) is an alkylating drug used as a conditioning regimen prior to allogeneic hematopoietic stem cell transplantation. Busulfan has wide inter- and intra-patient pharmacokinetic variability resulting in variable exposure leading to increased risk of toxicities or sub-optimal treatment outcomes. Therapeutic drug monitoring of busulfan using patient plasma samples would benefit clinicians by providing the ability to personalize the dose to achieve a target busulfan exposure.
Gender:
ALL
Ages:
All
Trial Updated:
03/31/2025
Locations: Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, Illinois +1 locations
Conditions: Subjects Treated With Busulfan
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AntiThrombotic Therapy to Ameliorate Clinical Complications in Community Acquired Pneumonia
NCT05848713
Recruiting
This is an international, open-label, stratified randomized controlled trial with Bayesian adaptive stopping rules to compare the effects of therapeutic-dose heparin vs. usual care pharmacological thromboprophylaxis on outcomes in patients admitted to hospital with community acquired pneumonia (CAP).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/31/2025
Locations: University of Chicago, Chicago, Illinois +61 locations
Conditions: Community-acquired Pneumonia
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Frequent Standardized Oral Care Using Human Milk in the Neonatal Intensive Care Unit
NCT06000761
Recruiting
Premature infants are susceptible to complications related to infrequent and non-standardized oral care. Although the benefits of frequent standardized oral care are known to reduce oral dysbiosis (increased level of potentially pathogenic bacteria) and its associated complications in critically ill adults leading to established evidence-based guidelines, no such information exists for VLBW infants. The proposed study will prospectively follow 168 VLBW infants for 4 weeks following birth.
Gender:
ALL
Ages:
Between 1 hour and 3 days
Trial Updated:
03/31/2025
Locations: Neonatal intensive care unit at Shands children's hospital at the Univeristy of Florida, Gainesville, Florida
Conditions: Ventilator Associated Pneumonia, Bronchopulmonary Dysplasia, Respiratory Disease
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Mindfulness Intervention for Caregivers of Autism in Rural Environments
NCT06169501
Recruiting
The purpose of this clinical trial is to investigate the effectiveness of a mobile app-based mindfulness program in improving the mental well-being of caregivers with a child diagnosed with autism spectrum disorder (ASD) who live in rural areas of Maine. The primary question the investigators aim to answer is whether this mindfulness intervention can reduce stress and anxiety in these rural caregivers of children with ASD. Participants in the trial will engage in a 30-day mindfulness program tha... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/31/2025
Locations: Glickman Lauder Center of Excellence, Portland, Maine
Conditions: Stress, Anxiety
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