Case Management Dyad
NCT06162897
Recruiting
The overall goal of this study is to test whether dyadic and focused case management will (1) improve financial wellbeing, (2) improve access to food, (3) increase linkage and retention rates for individuals living with HIV or those taking PrEP (PrEP persistence), and (4) increase the proportion of individuals living with HIV who are virally suppressed (viral suppression) when compared to routine Ryan White Non-Medical Case Management.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/09/2025
Locations: University of Chicago, Chicago, Illinois
Conditions: HIV, Pre-exposure Prophylaxis, Case Management
Register for Updates
Comparison of Methods for Recording Post Operative Pain
NCT06206148
Recruiting
The purpose of the current study is to identify the optimal method of collection of pain intensity data. The study will compare three collection methods: a hand-written pain journal, a smartphone app, and a novel electronic pain recorder device. Patients will be randomly assigned to one of three methods and instructed to record their pain level as often as they like. The number of pain intensity recordings per day will then be compared across groups.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/09/2025
Locations: Zuckerberg San Francisco General Hospital, San Francisco, California
Conditions: Pain, Postoperative
Register for Updates
Delta-8-THC vs. Delta-9-THC on Simulated Driving Performance
NCT06218550
Recruiting
Delta-8-THC is an isomer of delta-9-THC that has become widely available due to the legalization of hemp and its derivatives. Very little controlled research has been conducted with delta-8-THC and some research suggests it produces similar effects to delta-9-THC, albeit at lower potency. The present study will evaluate the dose effects of delta-8-THC, compared with delta-9-THC, on simulated driving performance, field sobriety tests, cognitive performance, and biomarkers of exposure to cannabino... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
07/09/2025
Locations: Johns Hopkins Behavioral Pharmacology Research Unit, Baltimore, Maryland
Conditions: Cannabis
Register for Updates
Augmented Reality For MRI-Guided Interventions
NCT06224933
Recruiting
The purpose of this study is to determine feasibility and safety of using an augmented reality system in patients undergoing MRI-Guided needle procedures.
Gender:
ALL
Ages:
Between 3 years and 21 years
Trial Updated:
07/09/2025
Locations: Children's National Hospital, Washington, District of Columbia
Conditions: Infections, Pain, Diagnosis
Register for Updates
MUSE-S Headband System for Improving Anxiety and Insomnia Among Breast Cancer Survivors
NCT06274034
Recruiting
This early phase I trial evaluates the feasibility and impact of a meditation headband system (MUSE-S) for breast cancer survivors. Anxiety and insomnia are among the most common distresses in breast cancer survivors during and after chemotherapy, in part due to the side effects of chemotherapy, fear of cancer coming back, progression of the cancer, and uncertainty of the future. These distresses impair patients' well-being and quality of life (QOL) in general, and their cancer treatment adheren... Read More
Gender:
FEMALE
Ages:
Between 18 years and 80 years
Trial Updated:
07/09/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Breast Carcinoma
Register for Updates
H01 in Adults With Interstitial Lung Disease (The SOLIS Study)
NCT06325696
Recruiting
Background: Interstitial lung disease affects the tissues that aid the transfer of oxygen and carbon dioxide between the air and the bloodstream. The disease can cause fibrosis, a thickening and scarring of lung tissue. Fibrosis often continues getting worse, and most people with this disease die in 3 to 5 years. Objective: To test a study drug (hymecromone) in people with interstitial lung disease or lung fibrosis. Eligibility: People aged 18 years and older with interstitial lung disease... Read More
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
07/09/2025
Locations: NIEHS Clinical Research Unit (CRU), Research Triangle Park, North Carolina
Conditions: Interstitial Lung Disease, Idiopathic Pulmonary Fibrosis, Lung Diseases, Interstitial
Register for Updates
Positive Psychology Intervention for Hematopoietic Stem Cell Transplantation Survivors
NCT06328127
Recruiting
This randomized clinical trial is evaluating the impact of a positive psychology intervention (PATH) on anxiety symptoms, depression symptoms, and quality of life in survivors of hematopoietic stem cell transplant (HSCT) compared to usual care.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/09/2025
Locations: Moffitt Cancer Center, Tampa, Florida +2 locations
Conditions: Hematopoietic Stem Cell Transplant
Register for Updates
Decreasing Nightmares in Adults With Narcolepsy
NCT06383806
Recruiting
The purpose of this clinical trial is learn whether a behavioral (non-medication) treatment can reduce nightmares in adults with narcolepsy. All participants will receive the treatment and will complete three assessments. Half of the participants will receive the treatment after the first assessment, and half will receive it after the second assessment. Romantic partners of participants with narcolepsy will also be eligible to enroll in the study. Partners will complete three assessments but wil... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/09/2025
Locations: University of Utah, Salt Lake City, Utah
Conditions: Narcolepsy, Narcolepsy Type 1, Narcolepsy With Cataplexy, Narcolepsy Without Cataplexy, Nightmare, Nightmare Disorder With Associated Other Sleep Disorder
Register for Updates
Imaging Depression in Parkinson's Disease
NCT06402955
Recruiting
The goal of this observational study is to identify targetable neural substrates of depression in Parkinson's Disease for the first time in people with Parkinson's between the ages of 40 and 80, who are experiencing symptoms of depression.
Gender:
ALL
Ages:
Between 40 years and 80 years
Trial Updated:
07/09/2025
Locations: Yale University, New Haven, Connecticut
Conditions: Parkinson's Disease, Major Depressive Disorder
Register for Updates
Psilocybin vs Ketamine for Alcohol Use Disorder
NCT06405607
Recruiting
This study will collect data that measures the effects of a psychedelic intervention on patients struggling with alcohol use disorder (AUD). The study design will be a double blind, randomized, active-comparator trial with two study arms. Subjects randomized to Arm 1 (n=40) will receive individual psychotherapy sessions plus a 30 mg dose of psilocybin. Arm 2 subjects (n=40) will receive individual psychotherapy sessions and a 0.75 mg/kg dose of ketamine.
Gender:
ALL
Ages:
Between 21 years and 65 years
Trial Updated:
07/09/2025
Locations: University of Iowa Health Care, Iowa City, Iowa
Conditions: Alcohol Use Disorder, Alcohol Dependence, Alcohol Abuse
Register for Updates
Optimal Intervention to Full Viral Suppression: Text Me, Alexis!
NCT06408350
Recruiting
Text Me, Alexis! is a three-arm randomized controlled trial (RCT) to determine the optimal and most cost-effective intervention for advancing trans women living with HIV to full viral suppression. Participants will be randomized (1:1:1) to Peer Health Navigation (PHN) alone, SMS (text messaging) alone, or PHN+SMS. Participants in the PHN alone and PHN+SMS arms will receive unlimited navigation sessions over 3 months. Participants in the SMS alone and PHN+SMS arms will receive 3 daily theory-base... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
07/09/2025
Locations: Friends Community Center, Los Angeles, California
Conditions: HIV
Register for Updates
ICoN-1 Phase 3 Study of the Efficacy and Safety of Treatment With MNKD-101, Clofazimine Inhalation Suspension
NCT06418711
Recruiting
This clinical trial is designed to compare the efficacy and safety of Clofazimine Inhalation Suspension versus placebo when added to guideline-based therapy (GBT)
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
07/09/2025
Locations: University of Alabama at Birmingham School of Medicine, Birmingham, Alabama +90 locations
Conditions: MAC Lung Disease, Treatment Refractory MAC Lung Disease, Mycobacterium Infections, Nontuberculous
Register for Updates