T-TAS® WS Method Comparison
NCT06710262
Recruiting
This study involves the collection of blood samples and measurement with the T-TAS PL assay to compare the performance of the T-TAS wS instrument to the T-TAS 01 instrument
Gender:
ALL
Ages:
21 years and above
Trial Updated:
03/07/2025
Locations: University of Florida Health Jacksonville, Jacksonville, Florida +1 locations
Conditions: Antiplatelet Therapy, Healthy Donors, Von Willebrand Disease (VWD)
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Efficacy of a Smartphone-Based JITAI to Reduce Drinking Among Adults Experiencing Homelessness
NCT06821295
Recruiting
Approximately 1 out of every 3 adults experiencing homelessness has a current alcohol use disorder (AUD). Alcohol use plays a central role in increased morbidity and mortality in this population, with some studies suggesting it plays a direct role in as many as 17% of deaths. Alcohol is also a leading cause of homelessness and contributes to its chronicity by inhibiting progress toward obtaining employment and a stable living environment. Shelter-based treatments are common, but compliance is of... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/07/2025
Locations: University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
Conditions: Alcohol Misuse, Homeless
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Beliefs, Attitudes, and Response to Genetic Testing in SarcomaPatients
NCT06875700
Recruiting
Genomic research has shown that a portion of leiomyosarcomas can be attributed to an underlying cancer predisposition syndrome. However, the optimal approach for incorporating germline testing into the care of these patients. This study is assessing the beliefs about the heritability of leiomyosarcoma and other cancer risks, and attitudes towards germline testing among leiomyosarcoma patients.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/07/2025
Locations: Huntsman Cancer Institute at the University of Utah, Salt Lake City, Utah
Conditions: Leiomyosarcoma
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Sample Collection and Tracking for the Developmental Therapeutics Clinic
NCT03269578
Recruiting
Background: People who join a study in the Developmental Therapeutics Clinic (DTC) have tests. These include blood draws and biopsies. Researchers collect data from these samples. Some people take part in more than one study at the DTC. At this time, data are connected only with one single study. Researchers want to access people s medical records. This will allow them to link the research data from all their studies they have or will take part in. Researchers also want to collect medical data... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/07/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Neoplasms, Lymphoma
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Effect of Preoperative Mobility Device Training on Postoperative Fall Incidence
NCT03857945
Recruiting
The purpose of this study is to determine whether preoperative mobility device training is beneficial in reducing incidence of postoperative falls in patients undergoing elective foot and ankle surgery requiring a postoperative period of no weight-bearing.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/07/2025
Locations: UAB Hospital Highlands, Birmingham, Alabama
Conditions: Injury; Muscle, Ankle, and Foot, Multiple
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A Study of Noninvasive Methods to Evaluate Skin and Mucosal Conditions
NCT04743362
Recruiting
The purpose of this study is to find out whether using noninvasive methods to study the appearance of lesions can improve diagnostic accuracy before a biopsy is required and help guide treatment planning. The database created to store these images is called an Image Repository, and it will be used to support clinical practice, teaching and training, and future research.The High-resolution OCT (Apollo Medical Optics) device ApolloVue® S100 Image System (medical device Class II) can provide both c... Read More
Gender:
ALL
Ages:
All
Trial Updated:
03/07/2025
Locations: Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York, New York
Conditions: Skin Lesion, Mucosal Lesion
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ERP to Improve Functioning in Veterans With OCD
NCT05240924
Recruiting
Obsessive compulsive disorder (OCD) is a debilitating psychiatric illness impacting work, social, and family functioning. Exposure and Response Prevention (ERP) is the sole evidence-based psychotherapy for OCD; however, no randomized controlled trials (RCTs) have examined the effectiveness of ERP among Veterans or individuals with both OCD and posttraumatic stress disorder (PTSD). This 4-year Hybrid Type I trial will compare outcomes of ERP to those of a control condition among Veterans with OCD... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/07/2025
Locations: East Orange Campus of the VA New Jersey Health Care System, East Orange, NJ, East Orange, New Jersey +17 locations
Conditions: Obsessive Compulsive Disorder (OCD), Comorbid Post-Traumatic Stress Disorder and OCD
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Study of Dato-Dxd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)
NCT05489211
Recruiting
TROPION-PanTumor03 will investigate the safety, tolerability, and anti-tumour activity of Datopotamab Deruxtecan (Dato-DXd) as Monotherapy and in Combination with Anticancer Agents in Patients with Advanced/Metastatic Solid Tumours.
Gender:
ALL
Ages:
Between 18 years and 130 years
Trial Updated:
03/07/2025
Locations: Research Site, Los Angeles, California +94 locations
Conditions: Endometrial Cancer, Gastric Cancer, Metastatic Castration-resistant Prostate Cancer, Ovarian Cancer, Colorectal Cancer, Urothelial Cancer, Biliary Tract Cancer
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Family Intervention to Prevent Childhood Obesity
NCT05606731
Recruiting
Consumption of sweetened beverages, media-viewing, and physical activity patterns are often established during early childhood, and family-based obesity interventions show effectiveness in shaping healthy behaviors and weight outcomes for young children, including Latino children. Missing from these interventions, however, are methods to increase accessibility and dissemination to multiple family caregivers. The proposed work will use a randomized study design to evaluate the impact a family-bas... Read More
Gender:
ALL
Ages:
2 years and above
Trial Updated:
03/07/2025
Locations: Head Start, Los Angeles, California
Conditions: Childhood Obesity
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A Study to Assess Adverse Events and Change in Disease Activity in Pediatric Participants (Age 6 Months to <2 Years) With Functional Constipation Who Are Treated With Linaclotide
NCT05760313
Recruiting
Functional constipation (FC) is a common healthcare problem in children of all ages, potentially due to genetic predisposition, inadequate fiber and fluid intake, and immobility. Currently, there are no pharmacological therapies approved for the treatment of FC. This study will assess adverse events and change in disease activity with linaclotide therapy in participants with FC. Linaclotide is an approved drug being developed for the treatment of FC in pediatric patients who meet modified Rome... Read More
Gender:
ALL
Ages:
Between 6 months and 23 months
Trial Updated:
03/07/2025
Locations: Velocity Clinical Research Phoenix /ID# 263871, Phoenix, Arizona +37 locations
Conditions: Functional Constipation
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LEVosimendan to Improve Exercise Limitation in Patients with PH-HFpEF
NCT05983250
Recruiting
This study will evaluate the efficacy of TNX-103 (oral levosimendan) compared with placebo in subjects with PH-HFpEF as measured by the change in 6-Minute Walk Distance (6 MWD; Day 1 to Week 12).
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
03/07/2025
Locations: Tenax Investigational Site, Birmingham, Alabama +53 locations
Conditions: Pulmonary Hypertension
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Platform Clinical Study for Conquering Scleroderma
NCT06195072
Recruiting
The goal of this clinical trial is to test efficacy of different investigational products (IPs) compared with placebo on the change from baseline to the end of the treatment period at Week 52 in lung capacity in participants with Interstitial Lung Disease Secondary to Systemic Sclerosis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/07/2025
Locations: University of Alabama - Division of Pulmonary and Critical Care Medicine, Birmingham, Alabama +31 locations
Conditions: Interstitial Lung Disease Due to Systemic Disease, Scleroderma
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