ost-traumatic stress disorder (PTSD) is a mental health condition that can happen after experiencing a traumatic or terrifying event. Anybody, regardless of their age or gender can develop PTSD; however, experiencing a traumatic event doesn’t necessarily mean that a person will develop this disorder.

PTSD is different from the sense of discomfort or sadness that people feel when recalling negative experiences; individuals who suffer from PTSD tend to experience disturbing thoughts, trouble sleeping, and both mental and physical distress on a regular basis, particularly when triggered by internal or stimulus including sounds, smells, places or feelings.

A doctor or a mental health professional will diagnose a person with PTSD after he or she has experienced symptoms for at least a month after the traumatic event occurred. Because PTSD can affect anybody at any point in time, there are treatments available to help you deal with your symptoms and overcome trauma. Currently, the most effective treatments include a mix of psychotherapy and medication to help the person deal with the depression or anxiety that can happen alongside PTSD.

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What Are Clinical Trials?

A clinical trial is a study conducted by medical professionals aiming to improve an existing treatment or find new alternatives for treating, preventing or diagnosing medical conditions. Many clinical trials begin at laboratories where research teams experiment with new drug ideas that could later become a treatment for a particular condition, then these medications are tested on volunteer human subjects to determine important factors such as it’s toxicity, side effects, and effectiveness.

Not all clinical trials involve testing new drugs or medications for treating a disease; some clinical trials rely merely on observation to determine how individuals respond or react to certain therapies or interventions. Other research studies might only want to collect blood or tissue samples to be later analyzed.

Regardless of the type of clinical trial, these studies are very rigorous and follow a predetermined set of rules and guidelines mandated by internal and external regulatory agencies. This means that clinical trials tend to be safe, and all participants are always closely monitored to ensure the trial runs smoothly and without any major inconveniences.

What Happens During A PTSD Clinical Trial?

Before you start participating in any type of clinical trial, a member of the research staff will make sure the entirety of the study has been explained to you, and they will ask you to sign an informed consent document.

An informed consent document is an official study document that explains the purpose of the study, any potential benefits and risks, and any other important information that you should know about before consenting to participate. It is important to note that even if you sign an informed consent document you are free to withdraw your participation from the trial at any point in time without consequence.

Because all clinical trials are different, what happens after giving consent will vary greatly depending on the type of study you enrolled into. Some mental health clinical trials involve medications; in these studies it is likely that the participant will be randomly assigned to a group to either receive a medication or a placebo. Researchers do this do determine the effectiveness of the medication whilst eliminating potential biases and confounders.

Will I Benefit From Participating In A Clinical Trial?

It is not possible to know whether a drug or a treatment being study in a clinical trial will be effective until it has gone through all phases and has been tested in many individuals. However, clinical trials are extremely important because they allow the medical field to move forward with the knowledge necessary to continue searching for cures, treatments, and preventive strategies for all kinds of conditions.

People participate in clinical trials for different reasons; some individuals with illnesses decide to participate in clinical trials for the opportunity of a potential new and effective treatment. Others choose to enroll in clinical trials to help science and medicine advance and helping others that might benefit from new drugs and treatments down the line.

Who Can Participate In A Clinical Trial?

Most clinical trials have an inclusion and exclusion criteria that outline who can and cannot participate based on the purpose of the study. While some trials want to have a very diverse sample and accept all kinds of volunteers, others might only look for individuals with a certain condition like PTSD or anxiety to test the medication or intervention on the specific population it is intended for.

Where Can I Find A PTSD Clinical Trial?

Clinical trials are often conducted by hospitals, universities or contract research organizations hired by pharmaceutical companies. If are thinking about enrolling in a PTSD clinical trial and would like to know what is available in your area, contact your doctor or mental health professional.

ClinicalTrials.gov: Recruiting Studies | Ptsd | Last update posted in the last 300 days Studies found on ClinicalTrials.gov by a search of: Recruiting Studies | Ptsd | Last update posted in the last 300 days

  • Efficacy of a Multi-level School Intervention for LGBTQ Youth
    on September 15, 2022 at 4:00 pm

    Conditions:   Depression;   Anxiety;   Post Traumatic Stress Disorder;   Coping Behavior;   Sexual Minority Stress;   Suicidality;   Substance Use;   Bullying;   HarassmentIntervention:   Behavioral: Proud & EmpoweredSponsors:   Washington University School of Medicine;   National Institute on Minority Health and Health Disparities (NIMHD);   University of Southern CaliforniaRecruiting

  • Risk and Resiliency Factors in the RCMP: A Prospective Investigation
    on September 2, 2022 at 4:00 pm

    Conditions:   Posttraumatic Stress Disorder;   Major Depressive Disorder;   Panic Disorder;   Generalized Anxiety Disorder;   Trauma;   Traumatic Stress Disorder;   Trauma and Stress Related Disorders;   Vicarious TraumaInterventions:   Behavioral: Emotional Resilience Skills Training (ERST);   Behavioral: Active MonitoringSponsors:   University of Regina;   Royal Canadian Mounted Police;   Government of Canada;   Ministry of Public Safety and Emergency Preparedness;   Canadian Institute for Public Safety Research and TreatmentRecruiting

  • A Scalable Model for Promoting Functioning and Well-Being Among Veterans With a History of Mental Health Challenges Via Meaningful Social Interactions: Project V-SPEAK!
    on August 18, 2022 at 4:00 pm

    Conditions:   Depression, Anxiety;   PTSDIntervention:   Other: Intervention (videoconferencing)Sponsor:   University of MichiganRecruiting

  • Early Psychological Intervention After Rape
    on August 5, 2022 at 4:00 pm

    Conditions:   Post Traumatic Stress Disorder;   Rape Sexual Assault;   Sexual Dysfunctions, Psychological;   Pelvic Floor Myalgia;   Pelvic Pain Syndrome;   Depression, Anxiety;   Sleep Disturbance;   Activity, Motor;   Cortisol DeficiencyIntervention:   Behavioral: Modified prolonged exposureSponsors:   St. Olavs Hospital;   Norwegian University of Science and Technology;   The Research Council of Norway;   Norwegian Women's Public Health Association (Norske Kvinners Sanitetsforening);   National Centre for Emergency Primary Health Care, NORCE;   UiT The Arctic University of NorwayRecruiting

  • Testing Adaptive Interventions to Improve Posttraumatic Stress Disorder Treatment Outcomes in Federally Qualified Health Centers
    on July 14, 2022 at 4:00 pm

    Condition:   PTSDInterventions:   Behavioral: Prolonged Exposure for Primary Care (PE-PC);   Behavioral: Full Prolonged Exposure;   Behavioral: Clinician Supported PTSD Coach AppSponsors:   University of Michigan;   National Institute of Mental Health (NIMH)Recruiting

  • Respiratory Training vs Interoceptive Exposure in the Treatment of Transdiagnostic Pathological Anxiety
    on June 22, 2022 at 4:00 pm

    Conditions:   Anxiety Disorders;   Trauma;   Generalized Anxiety Disorder;   Panic Disorder;   Agoraphobia;   Illness Anxiety Disorder;   Social Anxiety Disorder;   Posttraumatic Stress Disorder;   Acute Stress Disorder;   Adjustment Disorder With Anxious MoodInterventions:   Behavioral: Interoceptive Exposure;   Device: Capnometry-Guided Respiratory Intervention;   Behavioral: Psycho-EducationSponsors:   University of Texas at Austin;   Freespira, Inc.Recruiting

  • Efficacy of Evidence-Based PTSD Treatment Via Prebiotic Supplementation
    on June 21, 2022 at 4:00 pm

    Condition:   Post Traumatic Stress DisorderInterventions:   Dietary Supplement: Prebiotic Bar +CPT;   Behavioral: Non-Prebiotic Bar +CPTSponsors:   Rush University Medical Center;   Cures Within ReachRecruiting

  • The Effectiveness of Online Revised Written Exposure Therapy for PTSD
    on June 16, 2022 at 4:00 pm

    Conditions:   PTSD;   Subclinical PTSDInterventions:   Behavioral: written exposure therapy-revised version;   Behavioral: minimal contact controlSponsor:   Peking UniversityRecruiting

  • Art Therapy and Emotional Well Being in Military Populations With Posttraumatic Stress Symptoms
    on June 10, 2022 at 4:00 pm

    Conditions:   PTSD;   Military Activity;   Post-Traumatic Headache;   Posttraumatic Stress Disorder;   Posttraumatic Stress Disorder, Delayed Onset;   Sleep Disturbance;   Nightmare;   Irritable Mood;   Anger;   Combat and Operational Stress Reaction;   Combat Stress Disorders;   Military Family;   Military OperationsIntervention:   Behavioral: Art TherapySponsor:   Walter Reed National Military Medical CenterRecruiting

  • Study To Evaluate The Efficacy And Safety Of Balovaptan In Adults With Post-Traumatic Stress Disorder (PTSD)
    on June 2, 2022 at 4:00 pm

    Condition:   Stress Disorders, Post-TraumaticInterventions:   Drug: Balovaptan;   Drug: PlaceboSponsor:   Hoffmann-La RocheRecruiting

  • Effects of Stellate Ganglion Block in Post-traumatic Stress Disorder
    on May 26, 2022 at 4:00 pm

    Condition:   Post Traumatic Stress DisorderInterventions:   Drug: Bupivacaine;   Drug: SalineSponsor:   NYU Langone HealthRecruiting

  • Written Exposure Therapy to Improve Lives After Stress Exposure
    on May 25, 2022 at 4:00 pm

    Condition:   Post Traumatic Stress DisorderInterventions:   Behavioral: Written Exposure Therapy (WISE);   Behavioral: Non-emotional WritingSponsors:   University of North Carolina, Chapel Hill;   University of Florida Health;   Indiana University;   University of Massachusetts, Worcester;   Washington University School of Medicine;   Henry Ford Health System;   US Department of Veterans AffairsRecruiting

Match to PTSD Clinical Trials

  • Access to cutting-edge treatments
  • Latest clinical trials
  • Find trials in your area