ost-traumatic stress disorder (PTSD) is a mental health condition that can happen after experiencing a traumatic or terrifying event. Anybody, regardless of their age or gender can develop PTSD; however, experiencing a traumatic event doesn’t necessarily mean that a person will develop this disorder.

PTSD is different from the sense of discomfort or sadness that people feel when recalling negative experiences; individuals who suffer from PTSD tend to experience disturbing thoughts, trouble sleeping, and both mental and physical distress on a regular basis, particularly when triggered by internal or stimulus including sounds, smells, places or feelings.

A doctor or a mental health professional will diagnose a person with PTSD after he or she has experienced symptoms for at least a month after the traumatic event occurred. Because PTSD can affect anybody at any point in time, there are treatments available to help you deal with your symptoms and overcome trauma. Currently, the most effective treatments include a mix of psychotherapy and medication to help the person deal with the depression or anxiety that can happen alongside PTSD.

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What Are Clinical Trials?

A clinical trial is a study conducted by medical professionals aiming to improve an existing treatment or find new alternatives for treating, preventing or diagnosing medical conditions. Many clinical trials begin at laboratories where research teams experiment with new drug ideas that could later become a treatment for a particular condition, then these medications are tested on volunteer human subjects to determine important factors such as it’s toxicity, side effects, and effectiveness.

Not all clinical trials involve testing new drugs or medications for treating a disease; some clinical trials rely merely on observation to determine how individuals respond or react to certain therapies or interventions. Other research studies might only want to collect blood or tissue samples to be later analyzed.

Regardless of the type of clinical trial, these studies are very rigorous and follow a predetermined set of rules and guidelines mandated by internal and external regulatory agencies. This means that clinical trials tend to be safe, and all participants are always closely monitored to ensure the trial runs smoothly and without any major inconveniences.

What Happens During A PTSD Clinical Trial?

Before you start participating in any type of clinical trial, a member of the research staff will make sure the entirety of the study has been explained to you, and they will ask you to sign an informed consent document.

An informed consent document is an official study document that explains the purpose of the study, any potential benefits and risks, and any other important information that you should know about before consenting to participate. It is important to note that even if you sign an informed consent document you are free to withdraw your participation from the trial at any point in time without consequence.

Because all clinical trials are different, what happens after giving consent will vary greatly depending on the type of study you enrolled into. Some mental health clinical trials involve medications; in these studies it is likely that the participant will be randomly assigned to a group to either receive a medication or a placebo. Researchers do this do determine the effectiveness of the medication whilst eliminating potential biases and confounders.

Will I Benefit From Participating In A Clinical Trial?

It is not possible to know whether a drug or a treatment being study in a clinical trial will be effective until it has gone through all phases and has been tested in many individuals. However, clinical trials are extremely important because they allow the medical field to move forward with the knowledge necessary to continue searching for cures, treatments, and preventive strategies for all kinds of conditions.

People participate in clinical trials for different reasons; some individuals with illnesses decide to participate in clinical trials for the opportunity of a potential new and effective treatment. Others choose to enroll in clinical trials to help science and medicine advance and helping others that might benefit from new drugs and treatments down the line.

Who Can Participate In A Clinical Trial?

Most clinical trials have an inclusion and exclusion criteria that outline who can and cannot participate based on the purpose of the study. While some trials want to have a very diverse sample and accept all kinds of volunteers, others might only look for individuals with a certain condition like PTSD or anxiety to test the medication or intervention on the specific population it is intended for.

Where Can I Find A PTSD Clinical Trial?

Clinical trials are often conducted by hospitals, universities or contract research organizations hired by pharmaceutical companies. If are thinking about enrolling in a PTSD clinical trial and would like to know what is available in your area, contact your doctor or mental health professional.

ClinicalTrials.gov: Recruiting Studies | Ptsd | Last update posted in the last 300 days Studies found on ClinicalTrials.gov by a search of: Recruiting Studies | Ptsd | Last update posted in the last 300 days

  • PTSD Treatment and Emotion Regulation Skills Training for Women With Military Sexual Trauma (PE+ER)
    on March 11, 2021 at 5:00 pm

    Conditions:   Stress Disorders, Post-Traumatic;   Anxiety Disorders;   Mental Disorder;   Traumatic Stress DisorderIntervention:   Behavioral: PE+ERSponsors:   Medical University of South Carolina;   Georgia State UniversityRecruiting

  • Hot Water Immersion Therapy for Mental Health
    on March 11, 2021 at 5:00 pm

    Conditions:   Anxiety Disorders;   Depression;   Post-traumatic Stress Disorder;   Heat;   Water ImmersionIntervention:   Procedure: lower-limb hot water immersionSponsors:   Lakehead University;   Northern Ontario School of MedicineRecruiting

  • The PaTHS Descriptive Correlational Longitudinal Study
    on March 8, 2021 at 5:00 pm

    Conditions:   Single-ventricle;   Posttraumatic Stress Disorder;   Psychosocial ImpairmentIntervention:   Sponsors:   Children's Mercy Hospital Kansas City;   University of Missouri, Kansas CityRecruiting

  • Art Therapy qEEG Study for Service Members With a Traumatic Brain Injury and Posttraumatic Stress Symptoms
    on March 1, 2021 at 5:00 pm

    Conditions:   Post-Traumatic Headache;   PTSD;   TBI;   TBI (Traumatic Brain Injury);   MTBI - Mild Traumatic Brain Injury;   Posttraumatic Stress Disorder;   Posttraumatic Stress Disorder, Delayed Onset;   Sleep Disturbance;   Nightmare;   Nightmares, REM-Sleep Type;   Headache;   Irritable Mood;   Anger;   Eating Disorders;   Combat and Operational Stress Reaction;   Combat Stress Disorders;   Military Operations;   Military Activity;   Military FamilyIntervention:   Behavioral: Art TherapySponsors:   Walter Reed National Military Medical Center;   National Intrepid Center of ExcellenceRecruiting

  • Couple HOPES (Helping Overcome PTSD and Enhance Satisfaction)
    on February 21, 2021 at 5:00 pm

    Condition:   Posttraumatic Stress DisorderIntervention:   Behavioral: Couple HOPES Guided, Internet-Delivered, Self-Help InterventionSponsor:   York UniversityRecruiting

  • Enhanced Skills Training in Affective and Interpersonal Regulation (ESTAIR) for Veterans With CPTSD: A Pilot RCT
    on February 12, 2021 at 5:00 pm

    Condition:   Complex Post-Traumatic Stress DisorderInterventions:   Behavioral: Enhanced Skills Training in Affective and Interpersonal Regulation;   Behavioral: Treatment as usualSponsors:   Combat Stress;   Edinburgh Napier UniversityRecruiting

  • Implementering PTSD Treatment
    on February 3, 2021 at 5:00 pm

    Conditions:   Post-traumatic Stress Disorder;   Leadership;   ImplementationInterventions:   Behavioral: LOCI;   Behavioral: CT-PTSD;   Behavioral: EMDRSponsor:   Norwegian Center for Violence and Traumatic Stress StudiesRecruiting

  • Translational Research Center for TBI and Stress Disorders: Virtual Assessment of Deployment Trauma and Rehabilitation
    on January 26, 2021 at 5:00 pm

    Conditions:   TBI (Traumatic Brain Injury);   PTSDInterventions:   Behavioral: V-TRACTS Assessment/Feedback;   Behavioral: OPTIONAL Brief Assessment of Thinking;   Behavioral: OPTIONAL STEP-Home-Brief;   Behavioral: OPTIONAL At-home Exercise Program;   Behavioral: OPTIONAL Referral to 12-week STEP-Home;   Behavioral: OPTIONAL Clinical ReferralSponsor:   VA Boston Healthcare SystemRecruiting

  • Integrated Intervention Post-Sexual Assault
    on January 26, 2021 at 5:00 pm

    Conditions:   Substance Use Disorders;   Posttraumatic Stress Disorder;   Sexual AssaultIntervention:   Behavioral: Written Exposure and Cognitive Behavioral TherapySponsors:   Medical University of South Carolina;   National Institute on Drug Abuse (NIDA)Recruiting

  • Reducing Cannabis Overuse With Prazosin
    on January 22, 2021 at 5:00 pm

    Conditions:   Cannabis Dependence;   Posttraumatic Stress DisorderIntervention:   Drug: Prazosin HydrochlorideSponsor:   University of WashingtonRecruiting

  • Physical Exercise for Treatment of Depression and Anxiety - RCT
    on January 19, 2021 at 5:00 pm

    Conditions:   Depression;   AnxietyInterventions:   Other: Physical Exercise;   Other: Relaxation TherapySponsors:   Region Örebro County;   Örebro University, Sweden;   Uppsala University;   Karolinska InstitutetRecruiting

  • Program for Alleviating and Resolving Trauma and Stress 1
    on January 19, 2021 at 5:00 pm

    Condition:   Post-traumatic Stress DisorderIntervention:   Behavioral: PARTS ProgramSponsors:   Cambridge Health Alliance;   Foundation for Self LeadershipRecruiting

Match to PTSD Clinical Trials

  • Access to cutting-edge treatments
  • Latest clinical trials
  • Find trials in your area