MAGIC AKI: Magnesium for the Prevention of HIOC-Associated AKI
NCT05730816
Recruiting
In this research study, investigators will test whether prophylactic high-dose IV Mg administration attenuates the risk of AKI in patients with malignant mesothelioma receiving intraoperative chemotherapy (HIOC) with cisplatin compared to placebo .
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/09/2024
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Mesothelioma
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Smoking Cessation Intervention for American Indian Women Experiencing Intimate Partner Violence
NCT06357767
Recruiting
The goal of this project is to refine and test a culturally-tailored smoking cessation intervention for American Indian women who have experienced intimate partner violence (IPV). The primary aims of this study are to: (a) use a community-based participatory approach to refine intervention materials and finalize pilot intervention methodology for a culturally tailored, trauma-informed smoking cessation intervention for AI women who have experienced IPV; (b) examine feasibility, acceptability, sa... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
08/09/2024
Locations: Black Hills Center for American Indian Health, Rapid City, South Dakota
Conditions: Smoking Cessation, Cigarette Smoking
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Don't Go There: A Geospatial mHealth App for Gambling Disorder
NCT04158037
Recruiting
The goal of this project is to develop and to test the efficacy of a novel mHealth app for gambling disorder. The app capitalizes on smartphones' global positioning software (GPS) that recognizes a user's location to within 15 feet. Users will receive an alert of this go near a gambling venue. The project will conduct a 12-week pilot randomized clinical trial to test the short-term efficacy of the app with gambling disorder individuals.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/09/2024
Locations: Saint Louis University, Saint Louis, Missouri
Conditions: Gambling Disorder
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The Zonisamide and Reinforcement for Reducing Alcohol Use (ZARRA) Study
NCT05134857
Recruiting
A phase II randomized, double-blind, placebo-controlled clinical trial (RCT) to evaluate the ability of zonisamide (ZON) to decrease alcohol use among treatment-seeking adults with an alcohol use disorder (AUD).
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
08/09/2024
Locations: Washington State University, Spokane, Washington
Conditions: Alcohol Use Disorder (AUD)
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Screening for Autism in 9-Month-Olds by Measuring Social Visual Engagement
NCT05916430
Recruiting
The goal of this project is to measure the clinical utility of an objective and quantitative eye-tracking assay collected on a standalone, mobile investigational device to accurately screen 9-month-old infants for autism spectrum disorder and other actionable delays.
Gender:
ALL
Ages:
Between 8 months and 10 months
Trial Updated:
08/09/2024
Locations: Children's Healthcare of Altanta, Atlanta, Georgia +1 locations
Conditions: Autism, Infant Development
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A Study to Evaluate the Performance, Usability, and Result Interpretation of INSTI® HIV Self-Test
NCT06368453
Recruiting
The objective of this study is to evaluate the performance, usability, and result interpretation of the INSTI® HIV Self-Test (referred to INSTI® HIV ST) in the intended use population across the United States (US). The INSTI® HIV Self-Test is a single use in vitro test that is used as a self-test for the detection of antibodies to HIV-1 and HIV-2 in human fingerstick blood. This study is designed to evaluate INSTI® HIV ST performance in the hands of non-professionals and untrained lay users who... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/09/2024
Locations: Therafirst Medical Center, Fort Lauderdale, Florida
Conditions: Human Immunodeficiency Virus I Infection, Human Immunodeficiency Virus II Infection
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Sinai Vein Stent Registry
NCT02600936
Recruiting
The Sinai Vein Stent Registry aims to establish and maintain a registry of patients who have undergone a vein stent placement procedure at The Mount Sinai Medical Center. The purpose of this study is to monitor and evaluate the long-term outcomes of venous stents placed to treat venous outflow obstruction. Outcome variables that will be assessed are: patency rate, reintervention rate, occurrence of any complications, clinical improvement, and quality of life. Venous outflow obstruction is define... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/08/2024
Locations: Icahn School of Medicine at Mount Sinai, New York, New York
Conditions: Peripheral Venous Outflow Obstruction
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Gemcitabine, Nab-Paclitaxel, and Bosentan for the Treatment of Unresectable Pancreatic Cancer
NCT04158635
Recruiting
This phase I trial studies the side effects and best dose of bosentan and how well it works when given together with gemcitabine and nab-paclitaxel for the treatment of pancreatic cancer that cannot be removed by surgery (unresectable). Bosentan may block the hormone endothelin and prevent the growth and spread of pancreatic cancer. Drugs used in chemotherapy, such as gemcitabine and nab-paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stoppin... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/08/2024
Locations: City of Hope Medical Center, Duarte, California
Conditions: Stage III Pancreatic Cancer AJCC v8, Stage IV Pancreatic Cancer AJCC v8, Unresectable Pancreatic Carcinoma
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Belantamab Mafodotin, Pomalidomide and Dexamethasone for the Treatment of High-Risk Myeloma
NCT05208307
Recruiting
This phase II trial studies the effect of belantamab mafodotin, pomalidomide, and dexamethasone in treating patents with high-risk myeloma. Belantamab mafodotin is a monoclonal antibody, called belantamab, linked to a chemotherapy drug, called mafodotin. Belantamab is a form of targeted therapy because it attaches to specific molecules on the surface of cancer cells, known as BCMA receptors, and delivers mafodotin to kill them. Chemotherapy drugs, such as pomalidomide, work in different ways to... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/08/2024
Locations: Emory University/Winship Cancer Institute, Atlanta, Georgia
Conditions: Plasma Cell Myeloma
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Erector Spinae Regional Anesthesia for Pain Control
NCT05794828
Recruiting
Interventional study to use erector spinae plane block (ESPB) on diagnoses of posterior or lateral rib fractures, vertebral fractures, pancreatitis, pancreatic cancer, renal colic, and back pain for multimodal pain therapy to determine its assistance with pain relief as well as the patient's use of opiates after block completion
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/08/2024
Locations: Crozer Chester Medical Center, Ridley Park, Pennsylvania +3 locations
Conditions: Pain Management
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Single Session Intervention to Promote Hope
NCT06375876
Recruiting
The purpose of this study is to develop a brief, self-guided single-session intervention (SSI) that targets the development of, or increase in, hope, and pilot test it for the primary outcomes of feasibility, acceptability/likeability, safety, and changes in hope, and the secondary outcomes of self-worth, empowerment, and emotional wellbeing among women experiencing intimate partner violence (IPV). The study will be conducted in 2 stages: intervention development (Intervention Development Stage)... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
08/08/2024
Locations: The Consultation Center at Yale, New Haven, Connecticut
Conditions: Domestic Violence
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Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery
NCT02734537
Recruiting
This phase II trial studies how well radiation therapy with or without cisplatin works in treating patients with stage III-IVA squamous cell carcinoma of the head and neck who have undergone surgery. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. It is not yet kno... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/08/2024
Locations: University of Alabama at Birmingham Cancer Center, Birmingham, Alabama +639 locations
Conditions: Head and Neck Squamous Cell Carcinoma, Hypopharyngeal Squamous Cell Carcinoma, Laryngeal Squamous Cell Carcinoma, Laryngeal Squamous Cell Carcinoma, Spindle Cell Variant, Lip and Oral Cavity Squamous Cell Carcinoma, p16INK4a Negative Oropharyngeal Squamous Cell Carcinoma, Stage III Hypopharyngeal Carcinoma AJCC v8, Stage III Laryngeal Cancer AJCC v8, Stage III Lip and Oral Cavity Cancer AJCC v8, Stage III Oral Cavity Verrucous Carcinoma, Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8, Stage IVA Hypopharyngeal Carcinoma AJCC v8, Stage IVA Laryngeal Cancer AJCC v8, Stage IVA Lip and Oral Cavity Cancer AJCC v8, Stage IVA Oral Cavity Verrucous Carcinoma, Stage IVA Oropharyngeal (p16-Negative) Carcinoma AJCC v8
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