Arizona is currently home to 1670 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Phoenix, Tucson, Scottsdale and Mesa. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Screening for Asymptomatic Coronary Artery Disease in Kidney Transplant Candidates
NCT03674307
Recruiting
The Canadian Australasian Randomized Trial of Screening Kidney Transplant Candidates for Coronary Artery Disease (CARSK) will test the hypothesis that eliminating the regular use of non-invasive screening tests for CAD AFTER waitlist activation is not inferior to regular (i.e., annual) screening for CAD during wait-listing for the prevention of Major Adverse Cardiac Events. Secondary analyses will assess the impact of screening on the rate of transplantation, and the relative cost-effectiveness... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/10/2024
Locations: University of Arizona, Tucson, Arizona
Conditions: Cardiovascular Diseases, End Stage Renal Disease, Kidney Transplantation, Dialysis Related Complication
Register for Updates
PARTNER 3 Trial - Aortic Valve-in-Valve
NCT03003299
Recruiting
This study will assess the safety and effectiveness of the SAPIEN 3/SAPIEN 3 Ultra transcatheter heart valve (THV) in patients with a failing aortic bioprosthetic valve.
Gender:
ALL
Ages:
All
Trial Updated:
05/08/2024
Locations: Banner University Medical Center, Phoenix, Arizona
Conditions: Aortic Stenosis, Aortic Stenosis, Severe
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Caffeine Optimization Versus Standard Caffeine Dosage (2B-2)
NCT05588934
Recruiting
This clinical trial will be a comparison between personalized recommended caffeine dosing regimen versus the standard recommended caffeine dosing regimen for sustaining performance during sleep deprivation and minimizing side effects and subsequent sleep disruption. The questions this study aims to answer are: Whether the personalized caffeine recommendations improve vigilance, sleepiness, and cognition after total sleep deprivation, compared to standard recommendations; Whether the personalized... Read More
Gender:
ALL
Ages:
Between 18 years and 39 years
Trial Updated:
05/07/2024
Locations: University of Arizona, Tucson, Arizona
Conditions: Sleep Deprivation, Caffeine
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The Revitalize Study in Older Adults at Risk for Alzheimer's Disease
NCT04018092
Recruiting
The goal of this multi-site double blinded randomized sham-controlled Phase II clinical trial is to test a novel, relatively low cost, low risk, and potentially high impact therapeutic intervention in older adults who are at increased risk for Alzheimer's disease. The intervention involves transcranial and intranasal delivery of near infrared (NIR) light via light emitting diodes, aka photobiomodulation. The overall hypothesis, based on animal and pilot studies, is that exposure to NIR stimulati... Read More
Gender:
ALL
Ages:
Between 65 years and 89 years
Trial Updated:
05/07/2024
Locations: University of Arizona, Tucson, Arizona
Conditions: Cognitive Aging, Alzheimer Disease, Protection Against
Register for Updates
The Breast Cancer Survivors and Partners Online Research Together (SUPORT) Project
NCT05676255
Recruiting
Many breast cancer survivors (estimated 70% in some studies) experience clinically significant depression and/or anxiety in the months and years after finishing cancer treatments. This research will build on the rigor of prior research to reduce breast cancer survivor depression and anxiety with a compassion meditation intervention called CBCT (Cognitively-Based Compassion Training) for online synchronous delivery that is also inclusive of informal caregivers (i.e., adult family members who live... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: University of Arizona, Tucson, Arizona
Conditions: Breast Cancer Female, Psychological Distress
Register for Updates
Improving Hypertension Medication Adherence for Older Adults
NCT05610059
Recruiting
This randomized controlled trial will assess the efficacy and scalability of a blood pressure technology system intervention. The investigators will enroll 224 older adults with hypertension to identify those who are nonadherent for one hypertension medication. The participants will be randomized to one of two groups (112 per group) to use the blood pressure system for 6-months. Both groups receive information about high blood pressure and medications. One group will also receive strategies that... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
05/03/2024
Locations: University of Arizona, Tucson, Arizona
Conditions: Aging, Medication Adherence, Hypertension
Register for Updates
Sham LaserCap vs. LaserCap SD vs. LaserCap HD+
NCT05365360
Recruiting
Androgenetic alopecia (AGA) is a prevalent disease, occurring in 80% of Caucasian men and 50% of Caucasian women by age 701. Treatments for AGA are limited, and presently the only FDA-approved medications for AGA are topical minoxidil and oral finasteride1. In addition to medical therapies, FDA-cleared medical devices are now utilized for the treatment of AGA as of 20072. These devices, termed low level laser therapy (LLLT), come in multiple forms including combs, helmets and sports cap wearabl... Read More
Gender:
ALL
Ages:
25 years and above
Trial Updated:
05/03/2024
Locations: Banner University Dermatology, Tucson, Arizona
Conditions: Androgenetic Alopecia
Register for Updates
A Study to Compare the Efficacy and Safety of Idecabtagene Vicleucel With Lenalidomide Maintenance Therapy Versus Lenalidomide Maintenance Therapy Alone in Adult Participants With Newly Diagnosed Multiple Myeloma Who Have Suboptimal Response After Autologous Stem Cell Transplantation
NCT06399393
Recruiting
The purpose of this study is to compare the efficacy, safety, and tolerability of ide-cel with lenalidomide (LEN) maintenance to that of LEN maintenance alone in adult participants with Newly Diagnosed Multiple Myeloma (NDMM) who have achieved a suboptimal response post autologous stem cell transplantation (ASCT).
Gender:
All
Ages:
18 years and above
Trial Updated:
05/01/2024
Locations: Banner MD Anderson Cancer Center, Gilbert, Arizona
Conditions: Multiple Myeloma
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Relationship Between Data Obtained With the LuGENE® Multiparameter Transcriptomics Blood Test and Clinical and Standard Laboratory Features of Patients With SLE (ReLATE)
NCT05845593
Recruiting
This is an open label study to determine the association of the data obtained with LuGENE®, a transcriptomic-based LDT, with standard evaluation of patients diagnosed with SLE, including clinical involvement, SLEDAI score, Physician Global Assessment (PGA) and standard laboratory measures, including ANA, anti-DNA, anti-RNP and complement components C3 and C4, as well as Patient Reported Outcomes capturing pain, fatigue and Health-Related Quality of Life. The test will be administered on one occa... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/01/2024
Locations: Arizona Arthritis & Rheumatology Research, PLLC, Phoenix, Arizona
Conditions: Lupus Erythematosus, Systemic
Register for Updates
National Collaborative to Improve Care of Children With Complex Congenital Heart Disease
NCT02852031
Recruiting
The purpose of this initiative is to improve care and outcomes for infants with HLHS by expanding the NPC-QIC national registry to gather clinical care process, outcome, and developmental data on infants with HLHS between diagnosis and 12 months of age, by improving the use of standards into everyday practice across pediatric cardiology centers, and by engaging parents as partners in the process.
Gender:
ALL
Ages:
15 months and below
Trial Updated:
05/01/2024
Locations: Phoenix Children's Hospital, Phoenix, Arizona
Conditions: Hypoplastic Left Heart Syndrome (HLHS)
Register for Updates
Trial to Evaluate Safety, PD & PK of IV Study Drug, QN-302, in Pts w/ Advanced or Metastatic Solid Tumors
NCT06086522
Recruiting
Goal: learn about QN-302 in patients with solid tumors (metastatic, or advanced cancer). Main questions: * What does the study drug do to human body (Pharmacodynamics \[='PD'\]) * What does the body do to study drug (how processed in body (Pharmacokinetics \[='PK'\]) - Safety Study drug by intravenous infusion ('IV') once weekly for 3 weeks every 4-week 'cycle.' Study treatment continues as long as patient and their study doctor agree that study treatment is in the best interest of the patien... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/30/2024
Locations: HonorHealth, Scottsdale, Arizona
Conditions: Solid Tumor
Register for Updates
Addressing Nocturnal Sleep/Wake Effects on Risk of Suicide in Older Adults
NCT04986007
Recruiting
Suicide is a leading cause of death in the US, and insomnia is a risk factor for suicidal thoughts and behaviors. In older adults, suicide is associated with impaired cognitive functioning, and insomnia, which is more prevalent in older adults, is also linked to disrupted cognition. However, there is limited evidence on whether treatment of insomnia can improve suicidal ideation (with or without improving cognition), and no evidence specifically in older adults. Additionally, no studies have inv... Read More
Gender:
ALL
Ages:
55 years and above
Trial Updated:
04/30/2024
Locations: Banner Whole Health Clinic, Tucson, Arizona
Conditions: Sleep Initiation and Maintenance Disorders, Suicidal Ideation
Register for Updates