The city of Tempe, Arizona, currently has 9 active clinical trials seeking participants for Healthy research studies.
Study to Evaluate the Effects of NMRA-323511 Among Healthy Elderly and Adults With Agitation Associated With Dementia Due to Alzheimer's Disease
Recruiting
This study consists of 2 parts, Part A and Part B. Part A is a single center, randomized, double-blind, placebo-controlled cohort designed to evaluate the safety, tolerability, and pharmacokinetics (PK) of NMRA-323511 among healthy elderly. Part B is a multicenter, randomized, double-blinded, placebo-controlled, parallel-group cohort to evaluate the safety, tolerability, and efficacy of NMRA-323511 among adults with Agitation Associated with Dementia due to Alzheimer's Disease. Part A consists... Read More
Gender:
ALL
Ages:
Between 55 years and 90 years
Trial Updated:
03/07/2025
Locations: Neumora Investigator Site, Tempe, Arizona
Conditions: Alzheimer's Disease, Healthy Elderly
A Cardiac Liability Study of Varegacestat in Healthy Participants
Recruiting
This clinical study is designed to study the effect of a single dose of varegacestat on cardiac repolarization in healthy adult participants.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
03/06/2025
Locations: Celerion, Tempe, Arizona
Conditions: Healthy Volunteer
Randomized, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study of PORT-77 Administered to Healthy Adult Participants
Recruiting
A First-in-Human 2-part, randomized, double-blind, placebo-controlled, single ascending dose, multiple ascending dose, and food effect, investigation of the administration of PORT-77 in healthy adult participants.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
02/24/2025
Locations: Celerion, Tempe, Arizona
Conditions: Healthy Adult Participants
A Study to Evaluate a Single-Dose Subcutaneous Axatilimab Compared With Intravenous Axatilimab in Healthy Participants
Recruiting
This study will be conducted to evaluate a Single-Dose Subcutaneous (SC) Axatilimab Compared With Intravenous Axatilimab in Healthy Participants.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
02/18/2025
Locations: Celerion, Inc, Tempe, Arizona
Conditions: Healthy Participants
A First-In-Human Study of TAK-004 in Healthy Adults
Recruiting
This study is the first study with TAK-004 conducted in human beings. Participants will receive either TAK-004 or placebo. The main aim of this study is to learn how safe TAK-004 is in healthy adults and how well participants tolerate one or more doses of TAK-004. Other aims are to learn about the effects of TAK-004 on the heart rate and blood pressure and if TAK-004 creates an immune response (immunogenicity). Another aim is to learn how the body of healthy adults affects TAK-004 (pharmacokinet... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
11/14/2024
Locations: Celerion, Tempe, Arizona
Conditions: Healthy Volunteers
A Phase I Study of CDX-622
Recruiting
This is a study to determine the safety of CDX-622 in healthy participants.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
11/14/2024
Locations: Celerion, Inc., Tempe, Arizona
Conditions: Healthy Participants
A Single and Multiple Ascending Dose Study of CK-4021586 in Healthy Adult Participants
Recruiting
The purposes of this study are to: * Learn about the safety and tolerability of CK 4021586 after a single dose and multiple doses in healthy subjects. * Find out how much CK-4021586 is in the blood after a single dose and multiple doses. * Determine the effect different doses of CK-4021586 on the pumping function of the heart. * Determine the effect of food in the stomach on how much CK-4021586 is in the blood after a single dose.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
08/05/2024
Locations: Celerion, Tempe, Arizona
Conditions: Healthy Participants
The Brain Processes Underlying Speech Motor Learning and Speech Production
Recruiting
The aim of this research is to develop protocols that selectively target and improve speech-motor learning processes. Participants will be asked to name pictures, read words/sentences, and listen to sounds while their speech signals will be collected during the study.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/02/2024
Locations: Arizona State University, Tempe, Arizona
Conditions: Healthy Adults
Auditory Prediction and Error Evaluation in the Speech of Individuals Who Stutter
Recruiting
Stuttering negatively impacts communication and reduces the overall quality of life and well-being of individuals who stutter. This study will provide a strong foundation for developing neural and behavioral interventions for stuttering. Participants will be asked to name pictures, read words/sentences silently or aloud, and listen to speech and nonspeech sounds while their speech, muscle, and brain signals are collected. Some participants may also receive brain stimulation while reading and spe... Read More
Gender:
ALL
Ages:
3 years and above
Trial Updated:
08/02/2024
Locations: Arizona State University, Tempe, Arizona
Conditions: Healthy Subjects, Stuttering, Developmental