There are currently 15 active clinical trials seeking participants for Hypertension research studies. The states with the highest number of trials for Hypertension participants are .
A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
NCT07064473
Recruiting
This study is open to adults with type 2 diabetes, high blood pressure, and cardiovascular disease. People can join the study if they have these conditions and do not have a history of heart failure. The purpose of this study is to find out if a medicine called vicadrostat, when taken with empagliflozin, helps reduce cardiovascular risk in people with these conditions. The study will compare this combination to a placebo version of vicadrostat with empagliflozin. Participants are put into 2 gro... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/19/2025
Locations: Pinnacle Research Group, LLC, Anniston, Alabama +1056 locations
Conditions: Diabetes Mellitus, Type 2, Hypertension, Cardiovascular Diseases
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Kidney Check: Diabetes, Blood Pressure & Kidney Health Checks & Care in Indigenous Communities.
NCT03595267
Recruiting
Faced with limited access to preventative health care services, Indigenous people living in rural and remote communities are at a higher risk of Chronic Kidney Disease (CKD) and kidney failure, when compared to the general population. The goal of this project is to perform point-of-care testing for CKD and its risk factors, including diabetes and high blood pressure, for individuals residing in rural and remote Indigenous communities across the Canadian provinces of Manitoba, British Columbia, A... Read More
Gender:
ALL
Ages:
Between 10 years and 80 years
Trial Updated:
06/05/2025
Locations: Alberta Health Services, Calgary, Alberta +2 locations
Conditions: Chronic Kidney Disease, Diabetes, Hypertension
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Impact of Canadian Haskap Berry Powder on Hypertension and Acuity in Women's Health
NCT06764121
Recruiting
Haskap berries are rich in cyanidin-3-O-glucoside (C3G), which has been shown in vitro to enhance endothelial function. Previous clinical studies suggest haskap berry supplementation may improve cognition, mood, blood pressure, and athletic performance, but research is limited. This trial aims to contribute to the growing body of evidence on the effects of haskap berry supplementation. The trial is a 2-period, randomized, double-blinded, cross-over design lasting 16 weeks. During the first peri... Read More
Gender:
FEMALE
Ages:
35 years and above
Trial Updated:
05/30/2025
Locations: Richardson Centre for Food Technology and Research, Winnipeg, Manitoba
Conditions: Hypertension, Alertness
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Stretching vs Walking for Lowering Blood Pressure
NCT05252208
Recruiting
High blood pressure is a leading risk factor for cardiovascular disease. Traditionally, one of the ways to treat or prevent high blood pressure is to prescribe aerobic exercise training (i.e. brisk walking). Stretching may also be effective because it may cause changes in blood vessel stiffness and therefore reduce resistance to blood flow. The study will assess a group of individuals (i.e. 96) participating in a supervised stretching or walking program five days per week for six months to deter... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/17/2025
Locations: University of Saskatchewan, Saskatoon, Saskatchewan
Conditions: Hypertension
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Micro-doses of Physical Activity for COPD
NCT05553223
Recruiting
Chronic obstructive pulmonary disease (COPD) is a disease of the lungs that makes it hard for people to breath. Those with COPD spend considerably more time sitting and lying and less time performing physical activity than healthy individuals. Those who are the most sedentary have a greater risk of heart and blood vessel disease, which may lead to an early death. This project will investigate the effect of sitting still for 3 hours on blood vessel health in individuals with COPD. It will also in... Read More
Gender:
ALL
Ages:
All
Trial Updated:
04/02/2025
Locations: University of British Columbia, Kelowna, British Columbia
Conditions: Chronic Obstructive Pulmonary Disease, Endothelial Dysfunction, Vascular Stiffness, Hypertension, Cardiovascular Diseases
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Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
NCT04278404
Recruiting
The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to evaluate the PK of understudied drugs currently being administered to children per SOC as prescribed by their treating provider.
Gender:
ALL
Ages:
Between 0 years and 20 years
Trial Updated:
03/11/2025
Locations: Phoenix Children's Hospital, Phoenix, Arizona +50 locations
Conditions: Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension, Pain, Hyperphosphatemia, Primary Hyperaldosteronism, Edema, Hypokalemia, Heart Failure, Menorrhagia, Insomnia, Pneumonia, Skin Infection, Arrythmia, Asthma in Children, Bronchopulmonary Dysplasia, Adrenal Insufficiency, Fibrinolysis; Hemorrhage, Hemophilia, Attention Deficit Hyperactivity Disorder, Multisystem Inflammatory Syndrome in Children (MIS-C), Kawasaki Disease, Coagulation Disorder, Down Syndrome
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The Effect of Pharmacist-Initiated Home Blood Pressure Monitoring on Blood Pressure Control in Women
NCT05991414
Recruiting
To evaluate the impact of home blood pressure monitoring when used in addition to pharmacist care, compared to usual care, in women with elevated blood pressure (BP). Randomized 1:1 two-arm controlled trial. Patients to be identified and screened by pharmacists. Patients with a BP \>140/90mmHg or \>130/80mmHg in those with diabetes will be invited to enroll in the study. Intervention: Patients will have BP assessed at baseline by the pharmacist, and they will receive a home blood pressure monit... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
03/08/2025
Locations: Hills Clinic Pharmacy, Aylmer, Ontario +25 locations
Conditions: Hypertension
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Accuracy Testing of Validated and Non-validated Home BP Devices Sold on the Online Market.
NCT06688409
Recruiting
This study aims to assess whether validated and non-validated blood pressure measuring devices sold on the online market are accurate in regards to the mean awake BP from ambulatory blood pressure monitoring.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/12/2025
Locations: Hôpital Sacré-Coeur de Montréal, Montreal, Quebec
Conditions: Hypertension
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Screening Using Portable Electronic Recorders for Sleep Apnea in Hypertensive At-Risk Populations (SUPER-SHARP Trial)
NCT05918120
Recruiting
Uncontrolled hypertension is associated with an increased risk of heart disease, stroke, and mortality. Obstructive sleep apnea (OSA) is common in hypertension and treatment using continuous positive airway pressure (CPAP) has been shown to effectively lower blood pressure. Despite its clinical significance, OSA remains underdiagnosed in patients with hypertension, because the current standard of care to diagnose OSA is in-laboratory polysomnography, which is inconvenient and often inaccessible... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/07/2025
Locations: Sunnybrook Health Sciences Centre, Toronto, Ontario +2 locations
Conditions: Obstructive Sleep Apnea, Hypertension
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Evaluating the Use of a Remote Telehome Monitoring Hypertension Program for Patients Receiving Virtual Care
NCT05300503
Recruiting
High blood pressure or hypertension (HTN) is very common and can lead to serious health issues and even death. Medications and lifestyle changes can be used to treat HTN. During the Coronavirus Disease-19 (COVID-19) pandemic, a lot of the care provided by doctors has become virtual, meaning that patients can be assessed by a doctor over the phone or video call without needing to go to a clinic or hospital. Although this is convenient, a lot of people cannot get their blood pressure (BP) checked... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/05/2024
Locations: The University of Ottawa Heart Institute, Ottawa, Ontario
Conditions: Hypertension
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Evaluation of Nurse-led Integrated Care of Complex Patients Facilitated By Telemonitoring: The SMaRT Study
NCT05543720
Recruiting
In Canada, 3 out of 4 Canadians aged 65 and older have at least one chronic condition, while 1 in 4 seniors reported having three or more. Caring for complex patients who usually have multiple chronic conditions (MCC) is one of the biggest challenges facing our healthcare system. For patients, the lack of coordination and continuity of care as they transfer between healthcare settings and healthcare providers (HCPs) often results in a higher risk of readmission, suboptimal and fragmented care pl... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/24/2024
Locations: William Osler Health System, Brampton, Ontario +3 locations
Conditions: Heart Failure，Congestive, Mental Health (Depression), Diabetes Mellitus, Chronic Obstructive Pulmonary Disease, Hypertension
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Metabolic Imaging of the Heart Using Hyperpolarized (13C) Pyruvate Injection
NCT02648009
Recruiting
The prevalence of congestive heart failure (CHF) in Canada is high, representing one of the health care system's most expensive diagnoses. Despite major advances in medicine, the mortality and morbidity from CHF remains great. Currently, magnetic resonance imaging (MRI) is used for non-invasive imaging of the cardiovascular system to enable the structure and anatomy of the organ to be visualized. However, current MRI methods have limitations when assessing and aiding in the management of CHF. A... Read More
Gender:
ALL
Ages:
Between 19 years and 75 years
Trial Updated:
04/19/2024
Locations: Sunnybrook Health Sciences Centre, Toronto, Ontario +1 locations
Conditions: Hypertension, Hypertrophy
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