Metastatic Breast Cancer Clinical Trials in Canada

A listing of 8 Metastatic Breast Cancer clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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There are currently 8 active clinical trials seeking participants for Metastatic Breast Cancer research studies. The states with the highest number of trials for Metastatic Breast Cancer participants are .

Study of Belzutifan (MK-6482) Plus Fulvestrant for ER+/HER2- Metastatic Breast Cancer (MK-6482-029/LITESPARK-029)

NCT06428396

Recruiting

The purpose of this study is to assess the efficacy and safety of belzutifan (MK-6482) plus fulvestrant compared to everolimus plus endocrine therapy (ET) (investigator's choice of fulvestrant or exemestane) in adults with estrogen receptor-positive, human epidermal growth factor receptor 2-negative (ER+/HER2-) unresectable metastatic breast cancer. There is no formal hypothesis testing in this study.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/12/2025

Locations: City of Hope - Phoenix ( Site 0006), Goodyear, Arizona +36 locations

City of Hope - Phoenix ( Site 0006), Goodyear, Arizona

Cedars Sinai Medical Center ( Site 0012), Beverly Hills, California

Moores Cancer Center at UC San Diego Health ( Site 0025), La Jolla, California

USC/Norris Comprehensive Cancer Center ( Site 0013), Los Angeles, California

USC Norris Oncology Hematology Newport Beach ( Site 0029), Newport Beach, California

Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital ( Site 0011), Marietta, Georgia

Southeastern Regional Medical Center ( Site 0010), Newnan, Georgia

CHRISTUS Highland ( Site 0005), Shreveport, Louisiana

Renown Regional Medical Center ( Site 0018), Reno, Nevada

MD Anderson ( Site 0015), Houston, Texas

Mays Cancer Center ( Site 0022), San Antonio, Texas

Centro de Investigaciones Metabólicas (CINME)-Oncology ( Site 0504), Caba, Buenos Aires

Hospital Británico de Buenos Aires-Oncology ( Site 0500), Ciudad autónoma de Buenos Aires, Buenos Aires

Instituto de Investigaciones Clínicas Mar del Plata ( Site 0502), Mar del Plata, Buenos Aires

Instituto Alexander Fleming-Alexander Fleming ( Site 0505), Ciudad Autónoma de Buenos Aires, Caba

Sanatorio Allende - Cerro-Oncology ( Site 0506), Córdoba, Cordoba

Instituto de Oncología de Rosario ( Site 0501), Rosario, Santa Fe

Jewish General Hospital ( Site 0400), Montreal, Quebec

Centro de Investigación del Maule ( Site 4106), Talca, Maule

Bradfordhill ( Site 4100), Santiago., Region M. De Santiago

FALP ( Site 4102), Santiago, Region M. De Santiago

Pontificia Universidad Catolica de Chile ( Site 4108), Santiago, Region M. De Santiago

IMAT S.A.S ( Site 1205), Monteria, Cordoba

Oncologos Del Occidente ( Site 1200), Pereira, Risaralda

Fundacion Valle del Lili ( Site 1204), Cali, Valle Del Cauca

Seoul National University Hospital ( Site 3100), Seoul, Not set

Samsung Medical Center ( Site 3101), Seoul, Not set

National Cheng Kung University Hospital ( Site 3300), Tainan, Not set

National Taiwan University Hospital ( Site 3301), Taipei, Not set

National Taiwan University Cancer Center ( Site 3302), Taipei, Not set

Faculty of Medicine - Khon Kaen University ( Site 3502), Muang, Khon Kaen

Faculty of Medicine Siriraj Hospital ( Site 3500), Bangkoknoi, Krung Thep Maha Nakhon

Songklanagarind Hospital ( Site 3501), Hat Yai, Songkhla

The Royal Cornwall Hospital ( Site 1904), Truro, England

St Bartholomews Hospital ( Site 1900), London, London, City Of

The Christie Hospital NHS Foundation Trust ( Site 1902), Withington, Manchester

Ipswich Hospital ( Site 1911), Ipswich, Suffolk

Conditions: Metastatic Breast Cancer

Learn More ›

A Study of Disitamab Vedotin With Other Anticancer Drugs in Solid Tumors

NCT06157892

Recruiting

This clinical trial is studying solid tumor cancers. A solid tumor is one that starts in part of your body like your lungs or liver instead of your blood. Once they've grown bigger in one spot or spread to other parts of the body, they're harder to treat. This is called advanced or metastatic cancer. Participants in this study must have breast cancer or gastric cancer. Participants must have tumors that have HER2 on them. This allows the cancer to grow more quickly or spread faster. There are f... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/06/2025

Locations: Banner-University Medical Center Tucson Campus, Tucson, Arizona +122 locations

Banner-University Medical Center Tucson Campus, Tucson, Arizona

Banner-University Medical Center Tucson, Tucson, Arizona

The University of Arizona Cancer Center-North Campus Pharmacy, Attn: Kelly Myrdal, Tucson, Arizona

University of Arizona Cancer Center - North Campus, Tucson, Arizona

The University of Arizona Cancer Center-Main, Tucson, Arizona

UC Irvine Medical Center, Orange, California

University of California, San Francisco | HDFCCC - Hematopoietic Malignancies, San Francisco, California

UCLA Department of Medicine - Hematology & Oncology, Santa Monica, California

Colorado West Healthcare System, dba Community Hospital, Grand Junction, Colorado

Colorado West Healthcare, dba Grand Valley Oncology, Grand Junction, Colorado

Danbury Hospital, Danbury, Connecticut

The Whittingham Cancer Center / Norwalk Hospital, Norwalk, Connecticut

Georgetown University Medical Center, Washington, District of Columbia

MedStar Georgetown University Hospital, Washington, District of Columbia

Moffitt Cancer Center - International Plaza, Tampa, Florida

H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida

Moffitt Cancer Center - McKinley Campus, Tampa, Florida

Moffitt McKinley Hospital, Tampa, Florida

Moffitt Cancer Center at Wesley Chapel, Wesley Chapel, Florida

Georgia Cancer Specialists - Athens, Athens, Georgia

Georgia Cancer Specialists - Annex, Atlanta, Georgia

Atlanta Cancer Care - Atlanta, Atlanta, Georgia

Georgia Cancer Specialists-Northside, Atlanta, Georgia

Northside Hospital, Inc.- Central Research Department, Atlanta, Georgia

Northside Hospital, Atlanta, Georgia

Georgia Cancer Specialists - Blairsville, Blairsville, Georgia

Georgia Cancer Specialists - Canton, Canton, Georgia

Atlanta Cancer Care - Cumming, Cumming, Georgia

Georgia Cancer Specialists - Cumming, Cumming, Georgia

Georgia Cancer Specialists - Decatur, Decatur, Georgia

Suburban Hematology-Oncology Associates - Duluth, Duluth, Georgia

Suburban Hematology-Oncology Associates- Lawrenceville, Lawrenceville, Georgia

Georgia Cancer Specialists - Macon, Macon, Georgia

Georgia Cancer Specialists - Marietta, Marietta, Georgia

Memorial Hospital, Shiloh, Illinois

Siteman Cancer Center - Shiloh, Shiloh, Illinois

Massachusetts General Hospital., Boston, Massachusetts

Brigham and Women's Hospital, Boston, Massachusetts

Dana Farber Cancer Institute, Boston, Massachusetts

Dana Farber Cancer Institute- Chestnut Hill, Newton, Massachusetts

Siteman Cancer Center - West County, Creve Coeur, Missouri

Siteman Cancer Center - North County, Florissant, Missouri

Saint Luke's Cancer Institute LLC, Kansas City, Missouri

Saint Luke's Hospital Investigational Pharmacy, Kansas City, Missouri

St Lukes Hospital, Kansas City, Missouri

Barnes-Jewish Hospital, Saint Louis, Missouri

Washington University in St Louis., Saint Louis, Missouri

Washington University School of Medicine - Siteman Cancer Center, Saint Louis, Missouri

Siteman Cancer Center - South County, Saint Louis, Missouri

Siteman Cancer Center - St Peters, Saint Peters, Missouri

Renown Regional Medical Center, Reno, Nevada

San Juan Oncology Associates, Farmington, New Mexico

Memorial Sloan Kettering Cancer Center - Main Hospital, New York, New York

Zangmeister Cancer Center, Columbus, Ohio

Saint Francis Hospital / Bon Secours - South Carolina, Greenville, South Carolina

Sarah Cannon Research Institute - Pharmacy, Nashville, Tennessee

SCRI Oncology Partners, Nashville, Tennessee

Tennessee Oncology-Nashville/Sarah Cannon Research Institute, Nashville, Tennessee

Parkland Health and Hospital System, Dallas, Texas

University of Texas Southwestern Medical Center - Simmons Cancer Center, Dallas, Texas

University of Texas Southwestern Medical Center-Simmons Cancer Center Pharmacy, Dallas, Texas

University of Texas Southwestern Medical Center Simmons Cancer Center - Redbird, Dallas, Texas

University of Texas Southwestern Medical Center Clinical Lab-Zale Lipshy University Hospital, Dallas, Texas

University of Texas Southwestern Medical Center-William P. Clements Jr. University Hospital, Dallas, Texas

University of Texas Southwestern Medical Center, Dallas, Texas

University of Texas Southwestern Simmons Cancer Center - Fort Worth, Fort Worth, Texas

University of Texas Southwestern Medical Center Simmons Cancer Center - Richardson/Plano, Richardson, Texas

Harborview Medical Center, Seattle, Washington

Fred Hutchinson Cancer Center / Seattle Cancer Care Alliance / University of Washington, Seattle, Washington

University of Washington Medical Center, Seattle, Washington

University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, Madison, Wisconsin

Carbone Cancer Center / University of Wisconsin, Madison, Wisconsin

Peninsula & South Eastern Hematology and Oncology Group (PASO), Frankston, Victoria

Slade Pharmacy Frankston, Frankston, Victoria

Slade Health, Mount Waverley, Victoria

Peninsula & South Eastern Hematology and Oncology Group (PASO), Frankston, Not set

BC Cancer Kelowna., Kelowna, British Columbia

Ottawa Hospital Cancer Centre, Ottawa, Ontario

Sunnybrook Health Sciences Centre, Toronto, Ontario

University Health Network, Princess Margaret Hospital, Toronto, Ontario

Universitatsklinikum Essen, Essen, Not set

Universitatsklinikum Heidelberg, Heidelberg, Not set

Klinikums rechts der Isar der TU München, Muenchen, Not set

A.O.U. Federico II, Napoli, Campania

Azienda Ospedaliera Universitaria (AOU) Federico II, Napoli, Campania

Istituto Nazionale Tumori IRCCS Fondazione G. Pascale., Napoli, Campania

Istituto Europeo di Oncologia, Milano, Lombardia

Niguarda Ca' Granda Hospital, Milano, Lombardia

Humanitas Istituto Clinico Catanese, Misterbianco (CT), Sicilia

Azienda Ospedaliera Universitaria Integrata di Verona., Verona, Veneto

A.O.U. Federico II- U.O.C. Diagnostica per lmmagini e Radioterapia, Napoli, Not set

Dong-A University Hospital, Busan, Other

National Cancer Center, Goyang-si, Other

Chungbuk National University Hospital, Cheongju-si, Not set

Gachon University Gil Medical Center, Incheon, Not set

Seoul National University Bundang Hospital, Seongnam-si, Not set

Korea University Anam Hospital, Seoul, Not set

Samsung Medical Center, Seoul, Not set

Seoul National University Hospital, Seoul, Not set

Severance Hospital Yonsei University Health System, Seoul, Not set

St. Vincent's Hospital, The Catholic University of Korea, Suwon-si, Not set

Quirén Salud Barcelona, Barcelona, Not set

Hospital Universitari Vall d´Hebron, Barcelona, Not set

CETIR Grup Medic, Barcelona, Not set

Hospital Universitario de Basurto, Bilbao, Not set

Grupo Hospitalario QuironSalud, Erandio Bizkaia, Not set

L'Institut Catala d'Oncologia., L'Hospitalet de Llobregat, Not set

Farmacia-Ensayos. Planta S - Hospital Universitario HM Sanchinarro-CIOCC-START Madrid, Madrid, Not set

START Madrid-CIOCC_Hospital HM Sanchinarro, Madrid, Not set

Ecg Medica Sl, Valencia, Not set

Hospital Clinico Universitario de Valencia, Valencia, Not set

National Cheng Kung University Hospital, Tainan, Not set

National Taiwan University Hospital, Taipei, Not set

National Taiwan University Cancer Center, Taipei, Not set

The Royal Marsden Hospital, Sutton, Surrey

St Bartholomew's Hospital, London, Not set

The Royal Marsden Hospital, London, Not set

The Royal Marsden NHS Foundation Trust (RM), London, Not set

The Christie NHS Foundation Trust, Manchester, Not set

The Royal Marsden NHS Foundation Trust, Sutton, Not set

Conditions: Breast Neoplasms, Gastroesophageal Junction Adenocarcinoma, HER2 Low Breast Neoplasms, HER2 Positive Breast Neoplasms, Stomach Neoplasms, Triple Negative Breast Neoplasms, Metastatic Breast Cancer, Metastatic Gastric Cancer, Advanced Breast Cancer, Advanced Gastric Cancer

Learn More ›

A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer

NCT05894239

Recruiting

This study will evaluate the efficacy and safety of inavolisib in combination with Phesgo (pertuzumab, trastuzumab, and rHuPH20 injection for subcutaneous use) compared with placebo in combination with Phesgo, as maintenance therapy, after induction therapy in participants with previously untreated HER2-positive advanced breast cancer (ABC).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/01/2025

Locations: Banner Health MD Anderson AZ, Gilbert, Arizona +174 locations

Banner Health MD Anderson AZ, Gilbert, Arizona

Disney Family Cancer Center, Burbank, California

Ellison Institute of Technology, Los Angeles, California

Georgetown Uni Hospital, Washington, District of Columbia

Medstar Research Institute, Hyattsville, Maryland

Dana Farber Cancer Institute, Boston, Massachusetts

Henry Ford Hospital, Detroit, Michigan

Renown Regional Medical Center, Reno, Nevada

Hackensack University Medical Center, Hackensack, New Jersey

Atrium Health, Charlotte, North Carolina

Hightower Clinical, Oklahoma City, Oklahoma

Renovatio Clinical - El Paso, El Paso, Texas

JPS Health Network, Fort Worth, Texas

Lumi Research, Kingwood, Texas

Renovatio Clinical, The Woodlands, Texas

Kadlec Clinic Hematology and Oncology, Kennewick, Washington

Swedish Medical Center, Seattle, Washington

Fundación CENIT para la Investigación en Neurociencias, Buenos Aires, Not set

Centro Oncologico Korben, Ciudad Autonoma Buenos Aires, Not set

Instituto de Oncología de Rosario, Rosario, Not set

Hospital Provincial del Centenario, Rosario, Not set

CER San Juan Centro Polivalente de Asistencia e Investigacion Clinica, San Juan, Not set

Clínica Viedma, Viedma Rio Negro, Not set

Blacktown Hospital, Blacktown, New South Wales

Kinghorn Cancer Centre, Darlinghurst, New South Wales

Gosford Hospital, Gosford, New South Wales

University of the Sunshine Coast, Sippy Downs, Queensland

Monash Health, Clayton, Victoria

Sir Charles Gairdner Hospital, Perth, Western Australia

Cliniques Universitaires St-Luc, Bruxelles, Not set

GHdC Site Les Viviers, Charleroi, Not set

Jessa Zkh (Campus Virga Jesse), Hasselt, Not set

Clinique Ste-Elisabeth, Namur, Not set

Hospital Sao Rafael - HSR, Salvador, Bahia

Crio - Centro Regional Integrado de Oncologia, Fortaleza, Ceará

Hospital Araujo Jorge, Goiania, Goiás

Hospital do Câncer de Londrina, Londrina, Paraná

Hospital do Cancer de Pernambuco - HCP, Recife, Pernambuco

Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Rio Grande Do Sul

Hospital Sao Lucas - PUCRS, Porto Alegre, Rio Grande Do Sul

Hospital de Amor Amazônia, Porto Velho, Rondônia

Hospital de Cancer de Barretos, Barretos, São Paulo

Instituto do Cancer do Estado de Sao Paulo - ICESP, Sao Paulo, São Paulo

Clinica de Pesquisa e Centro de Estudos em Oncologia Ginecologica e Mamaria Ltda, Sao Paulo, São Paulo

Arthur J.E. Child Comprehensive Cancer Center-Calgary, Calgary, Alberta

The Moncton Hospital, Moncton, New Brunswick

Eastern Health - General Hospital, St. John's, Newfoundland and Labrador

Sunnybrook Health Sciences Centre, Toronto, Ontario

Centre Hospitalier de l?Université de Montréal (CHUM), Montreal, Quebec

Jewish General Hospital, Montreal, Quebec

Hôpital du Sacré-Coeur de Montreal, Montreal, Quebec

Hopital du Saint Sacrement, Quebec City, Quebec

Allan Blair Cancer Center, Regina, Saskatchewan

Affiliated Hospital of Hebei University, Baoding, Not set

Beijing Cancer Hospital, Beijing, Not set

The First Hospital of Jilin University, Changchun City, Not set

Sichuan Provincial Cancer Hospital, Chengdu, Not set

Sichuan Provincial People's Hospital, Chengdu, Not set

Fujian Cancer Hospital, Fuzhou, Not set

Zhejiang Cancer Hospital, Hangzhou City, Not set

Harbin Medical University Tumor Hospital, Harbin, Not set

Shandong Cancer Hospital, Jinan, Not set

The First Affiliated Hospital to Henan University of Science and Technology, Luoyang, Not set

The Second Affiliated Hospital to Nanchang University, Nanchang, Not set

Guangxi Cancer Hospital of Guangxi Medical University, Nanning, Not set

Shantou Center Hospital, Shantou City, Not set

Tianjin Cancer Hospital, Tianjin, Not set

Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan City, Not set

Hubei Cancer Hospital, Wuhan, Not set

Clinica De La Costa, Barranquilla, Not set

Fundación CTIC - Centro de Tratamiento e Investigación sobre Cáncer Luis Carlos Sarmiento Angulo, Bogota, D.C., Not set

Oncomedica S.A., Monteria, Not set

Sociedad de Oncología y hematología del Cesar Ltda, Valledupar, Not set

Tampere University Hospital, Tampere, Not set

Turku Uni Central Hospital, Turku, Not set

Institut Sainte Catherine, Avignon, Not set

Centre Hospitalier de La Cote Basque, Bayonne, Not set

Polyclinique Bordeaux Nord Aquitaine, Bordeaux, Not set

Centre Georges Francois Leclerc, Dijon, Not set

Centre Oscar Lambret, Lille, Not set

Klinikum St. Marien, Amberg, Not set

HELIOS Klinikum Berlin-Buch, Berlin, Not set

Marienhospital Bottrop gGmbH, Bottrop, Not set

Gynonco Düsseldorf, MVZ Medical Center GmbH, Düsseldorf, Not set

Frauenarztpraxis Dr. Apel, Dr. Kolpin, Erfurt, Not set

Praxis für Interdisziplinäre Onkologie und Hämatologie GbR, Freiburg, Not set

Klinik & Poliklinik für Frauenheilkunde und Geburtshilfe, Campus Innenstadt, München, Not set

St. Franziskus Hospital Münster;Studiensekretariat der onkologischen Zentren, Münster, Not set

Caritas Klinik St. Theresia -Frauenklinik Brustzentrum, Saarbruecken, Not set

Gynäkologie Kompetenzzentrum, Stralsund, Not set

Universitätsfrauenklinik Ulm, Ulm, Not set

Queen Mary Hospital, Hong Kong, Not set

Tuen Mun Hospital, Hong Kong, Not set

Max Super Speciality Hospital, NEW Delhi Delhi, Delhi

Gujarat Cancer & Research Inst., Ahmadabad CITY, Gujarat

Sunshine Global Hospital (A unit of Baroda Medicare Pvt Ltd), Surat CITY, Gujarat

Artemis Hospital, Gurugram, Haryana

Sir H. N. Reliance Foundation Hospital and Research Centre, Mumbai, Maharashtra

National Cancer Institute, Nagpur, Maharashtra

Tata Medical Center, Kolkata, WEST Bengal

I.R.S.T Srl IRCCS, Meldola, Emilia-Romagna

Ospedale San Giovanni Addolorata, Roma, Lazio

Ospedale San Raffaele, Milano, Lombardia

Irccs Istituto Nazionale Dei Tumori (Int), Milano, Lombardia

Irccs Istituto Europeo Di Oncologia (IEO), Milano, Lombardia

Ospedale San Gerardo, Monza, Lombardia

A.O.U. Maggiore della Carità, Novara, Piemonte

Casa di Cura La Maddalena, Palermo, Sicilia

Ospedale Santa Maria Annunziata, Bagno a Ripoli, Toscana

"Azienda Ospedaliera Universitaria Integrata Verona Ospedale Borgo Trento", Verona, Veneto

King Hussein Cancer Center, Amman, Not set

University of Nairobi - Institute of Tropical and Infectious Diseases, Nairobi, Not set

National Cancer Center, Goyang-si, Not set

Seoul National University Hospital, Seoul, Not set

Severance Hospital, Yonsei University Health System, Seoul, Not set

Asan Medical Center, Seoul, Not set

Gangnam Severance Hospital, Seoul, Not set

Samsung Medical Center, Seoul, Not set

Seoul St Mary's Hospital, Seoul, Not set

Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Jalisco

OncoMed, Ciudad de México, Mexico CITY (federal District)

Centro Oncológico Hematológico Roma, Mexico City, Mexico CITY (federal District)

Hospital Universitario, Monterrey, Nuevo LEON

CENEIT Oncologicos, Mexico City, Not set

Sultan Qaboos Comprehensive Cancer Care & Research Center, Muscat, Not set

Centrum Onkologii im. Prof. Franciszka ?ukaszczyka, Bydgoszcz, Not set

Uniwersyteckie Centrum Kliniczne, Gda?sk, Not set

Szpital Morski im.PCK, Gdynia, Not set

Narodowy Instytut Onkologii Odzia? w Gliwicach, Gliwice, Not set

Przychodnia Lekarska KOMED, Roman Karaszewski, Konin, Not set

Szpital Wojewódzki im. Miko?aja Kopernika, Koszalin, Not set

Wielkopolskie Centrum Onkologii im. Marii Sk?odowskiej-Curie, Pozna?, Not set

Centrum Onkologii Instytut im.M. Sklodowskiej-Curie, Warszawa, Not set

National University Hospital, Singapore, Not set

National Cancer Centre, Singapore, Not set

Icon Cancer Centre Farrer Park, Singapore, Not set

Tan Tock Seng Hospital, Singapore, Not set

Hopelands Cancer Centre, Hilton, Not set

Charlotte Maxeke Academic Hospital, Johannesburg, Not set

Medical Oncology Centre of Rosebank, Johannesburg, Not set

Limpopo Cancer Research Institute, Polokwane, Not set

Steve Biko Academic Hospital, Pretoria, Not set

Chris Hani Baragwanath Clinical Trial Site, Soweto, Not set

Complejo Hospitalario Universitario A Coruña (CHUAC), A Coruña, LA Coruna

Hospital Universitari Dexeus - Grupo Quironsalud, Barcelona, Not set

Hospital Universitari Vall d'Hebron, Barcelona, Not set

Hospital General Universitario Gregorio Marañon, Madrid, Not set

Hospital Ramon y Cajal, Madrid, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

Hospital Clinico Universitario Virgen de la Victoria, Malaga, Not set

Hospital Universitario Virgen Macarena, Sevilla, Not set

National Taiwan Uni Hospital, Taipei, Not set

Tri-Service General Hospital, Taipei, Not set

Chang Gung Memorial Hospital-Linkou, Taoyuan County, Not set

Abderrahmen Mami Hospital, Ariana, Not set

Taher Maamouri Hospital, Nabeul, Not set

Habib Bourguiba Hospital, Sfax, Not set

Farhat Hached Hospital, Sousse, Not set

Institut Salah Azeiz, Tunis, Not set

Sakarya Training and Research Hospital, Adapazar?, Not set

Gulhane Training and Research Hospital, Ankara, Not set

Gazi University Medical Faculty, Ankara, Not set

Bakirkoy Dr. Sadi Konuk Egitim ve Arastirma Hastanesi, Tibbi Onkoloji, Bakirkoy / Istanbul, Not set

Dicle University Faculty of Medicine, Diyarbakir, Not set

Medipol Mega Üniversite Hastanesi Göztepe, Istanbul, Not set

Katip Celebi University Ataturk Training and Research Hospital, Izmir, Not set

Medical Park Seyhan Hospital, Seyhan, Not set

Hacettepe Uni Medical Faculty Hospital, Sihhiye/Ankara, Not set

Uganda Cancer Institute, Kampala, Not set

Belfast City Hospital, Belfast, Not set

Blackpool Victoria Hospital, Blackpool, Not set

Colchester General Hospital, Colchester, Essex, Not set

Mount Vernon Hospital, Northwood, Not set

Nottingham City Hospital, Nottingham, Not set

Churchill Hospital, Oxford, Not set

Conditions: Metastatic Breast Cancer

Learn More ›

Using a Blood Test to Monitor Metastatic Breast Cancer Treatment

NCT05804578

Recruiting

The goal of this observational study is to assess the effectiveness of the mDETECT breast cancer blood test at monitoring treatment response in women with metastatic breast cancer undergoing treatment.

Gender:

FEMALE

Ages:

18 years and above

Trial Updated:

07/22/2025

Locations: Kingston Health Sciences Centre - Cancer Centre of Southeastern Ontario, Kingston, Ontario +1 locations

Conditions: Metastatic Breast Cancer

Learn More ›

A Study of DB-1303/BNT323 vs Investigator's Choice Chemotherapy in HER2-Low, Hormone Receptor Positive Metastatic Breast Cancer (DYNASTY-Breast02)

NCT06018337

Recruiting

The goal of this clinical trial is to assess the efficacy of DB-1303/BNT323 compared with investigator's choice chemotherapy in terms of progression-free survival (PFS) by blinded independent central review (BICR) in the HR+, HER2-low (immunohistochemistry \[IHC\]2+/in situ hybridization \[ISH\]- and IHC 1+) population.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/16/2025

Locations: Research Site 1141-0, Tucson, Arizona +252 locations

Research Site 1141-0, Tucson, Arizona

Research Site 1114-0, Fullerton, California

Research Site 1107-0, Los Angeles, California

Research Site 1118-0, Orange, California

Research Site 1143-0, Sacramento, California

Research Site 1132-0, Santa Barbara, California

Research Site 1137-0, Aurora, Colorado

Research Site 1129-0, Lone Tree, Colorado

Research Site 1154-0, Jacksonville, Florida

Research Site 1145-0, Miami, Florida

Research Site 1150-0, Orange City, Florida

Research Site 1125-0, Palm Bay, Florida

Research Site 1110-0, Savannah, Georgia

Research Site 1124-0, Chicago Ridge, Illinois

Research Site 1147-0, Chicago, Illinois

Research Site 1152-0, Fort Wayne, Indiana

Research Site 1106-0, Merriam, Kansas

Research Site 1104-0, Louisville, Kentucky

Research Site 1122-0, Silver Spring, Maryland

Research Site 8639-0, Silver Spring, Maryland

Research Site 1109-0, Kansas City, Missouri

Research Site 1111-0, Florham Park, New Jersey

Research Site 1157-0, Santa Fe, New Mexico

Research Site 1148-0, Staten Island, New York

Research Site 1105-0, Westbury, New York

Research Site 1144-0, Chapel Hill, North Carolina

Research Site 1138-0, Akron, Ohio

Research Site 1160-0, Cincinnati, Ohio

Research Site 1133-0, Eugene, Oregon

Research Site 1126-0, Tigard, Oregon

Research Site 1134-0, Broomall, Pennsylvania

Research Site 1123-0, Horsham, Pennsylvania

Research Site 1149-0, Knoxville, Tennessee

Research Site 1102-0, Nashville, Tennessee

Research Site 1101-0, Dallas, Texas

Research Site 1116-0, Denison, Texas

Research Site 1115-0, Houston, Texas

Research Site 1117-0, San Antonio, Texas

Research Site 1130-0, Salt Lake City, Utah

Research Site 1108-0, Fairfax, Virginia

Research Site 1131-0, Fairfax, Virginia

Research Site 1127-0, Roanoke, Virginia

Research Site 5411-0, Bahia Blanca, Buenos Aires

Research Site 5414-0, Caba, Buenos Aires

Research Site 5405-0, La Plata, Buenos Aires

Research Site 5413-0, Mar del Plata, Buenos Aires

Research Site 5408-0, Quilmes, Buenos Aires

Research Site 5403-0, Caba, Ciudad Autonoma Buenos Aires

Research Site 5402-0, Viedma, Rio Negro

Research Site 5401-0, Rosario, Santa Fe

Research Site 5406-0, Rosario, Santa Fe

Research Site 5404-0, San Miguel de Tucuman, Tucuman

Research Site 5407-0, Ciudad Autonoma Buenos Aires, Not set

Research Site 5409-0, Ciudad Autonoma Buenos Aires, Not set

Research Site 6108-0, Camperdown, New South Wales

Research Site 6116-0, Kingswood, New South Wales

Research Site 6109-0, Liverpool, New South Wales

Research Site 6102-0, Sydney, New South Wales

Research Site 6106-0, Birtinya, Queensland

Research Site 6101-0, South Brisbane, Queensland

Research Site 6107-0, Southport, Queensland

Research Site 6104-0, Townsville, Queensland

Research Site 6110-0, Adelaide, South Australia

Research Site 6103-0, Bendigo, Victoria

Research Site 6105-0, St. Albans, Victoria

Research Site 6113-0, Traralgon, Victoria

Research Site 6114-0, Perth, Western Australia

Research Site 3201-0, Brussels, Not set

Research Site 3204-0, Gent, Not set

Research Site 3205-0, Jette, Not set

Research Site 3203-0, Leuven, Not set

Research Site 3207-0, Liege, Not set

Research Site 3202-0, Roeselare, Not set

Research Site 1007-0, Winnipeg, Manitoba

Research Site 1003-0, Brampton, Ontario

Research Site 1001-0, Toronto, Ontario

Research Site 1004-0, Montreal, Quebec

Research Site 1005-0, Montreal, Quebec

Research Site 1006-0, Montreal, Quebec

Research Site 1002-0, Sherbrooke, Quebec

Research Site 8640-0, Hefei, Anhui

Research Site 8614-0, Hefei, Anhui

Research Site 8601-0, Beijing, Beijing

Research Site 8625-0, Beijing, Beijing

Research Site 8653-0, Beijing, Beijing

Research Site 8627-0, Chongqing, Chongqing

Research Site 8651-0, Fuzhou, Fujian

Research Site 8638-0, Xiamen, Fujian

Research Site 8630-0, Lanzhou, Gansu

Research Site 8604-0, Guangzhou, Guangdong

Research Site 8628-0, Guangzhou, Guangdong

Research Site 8621-0, Huizhou, Guangdong

Research Site 8622-0, Zhuhai, Guangdong

Research Site 8615-0, Nanning, Guangxi

Research Site, Baoding, Hebei

Research Site 8629-0, Baoding, Hebei

Research Site 8645-0, Shijiazhuang, Hebei

Research Site 8619-0, Harbin, Heilongjiang

Research Site 8649-0, Anyang, Henan

Research Site 8609-0, Luoyang, Henan

Research Site 8648-0, Weihui, Henan

Research Site 8605-0, Zhengzhou, Henan

Research Site 8623-0, Zhengzhou, Henan

Research Site 8637-0, Wuhan, Hubei

Research Site 8608-0, Wuhan, Hubei

Research Site 8633-0, Xiangyang, Hubei

Research Site 8635-0, Changsha, Hunan

Research Site 8654-0, Yongzhou, Hunan

Research Site 8646-0, Huai'an, Jiangsu

Research Site 8607-0, Nanjing, Jiangsu

Research Site 8624-0, Xuzhou, Jiangsu

Research Site 8631-0, Nanchang, Jiangxi

Research Site 8612-0, Changchun, Jilin

Research Site 8618-0, Changchun, Jilin

Research Site 8644-0, Changchun, Jilin

Research Site 8636-0, Dalian, Liaoning

Research Site-8636-0, Dalian, Liaoning

Research Site 8643-0, Shenyang, Liaoning

Research Site 8642-0, Shenyang, Liaoning

Research Site 8634-0, Jinan, Shandong

Research Site 8613-0, Jining, Shandong

Research Site 8610-0, Linyi, Shandong

Research Site 8650-0, Weihai, Shandong

Research Site 8603-0, Shanghai, Shanghai

Research Site 8602-0, Shanghai, Shanghai

Research Site 8611-0, Xi'an, Shanxi

Research Site 8606-0, Chengdu, Sichuan

Research Site 8626-0, Neijiang, Sichuan

Research Site 8647-0, Zigong, Sichuan

Research Site 8617-0, Tianjin, Tianjin

Research Site 8616-0, Urumqi, Xinjiang

Research Site 8632-0, Kunming, Yunnan

Research Site 8652-0, Hangzhou, Zhejiang

Research Site 8620-0, Hangzhou, Zhejiang

Research Site 8641-0, Hangzhou, Zhejiang

Research Site 3311-0, Marseille cedex 20, Bouches-du-Rhône

Research Site 3303-0, La Rochelle cedex, Charente Maritime

Research Site 3312-0, Besancon Cedex, Doubs

Research Site 3308-0, Nimes, Gard

Research Site 3314-0, Bordeaux, Gironde

Research Site 3305-0, Toulouse cedex 09, Haute Garonne

Research Site 3309-0, Limoges, Haute Vienne

Research Site 3304-0, Montpellier, Herault

Research Site 3310-0, Saint Herblain, Loire Atlantique

Research Site 3301-0, Angers Cedex 2, Maine Et Loire

Research Site 3315-0, Lille cedex, Nord

Research Site 3306-0, Bayonne cedex, Pyrenees Atlantiques

Research Site 3318-0, Pierre Benite cedex, Rhone

Research Site 3313-0, Rouen, Seine Maritime

Research Site 3307-0, Avignon Cedex 9, Vaculuse

Research Site 3302-0, Creteil Cedex, Val De Marne

Research Site 3316-0, Paris, Not set

Research Site 4907-0, Erlangen, Bayern

Research Site 4909-0, Wiesbaden, Hessen

Research Site 4904-0, Bottrop, Nordrhein Westfalen

Research Site 4901-0, Witten, Nordrhein Westfalen

Research Site 4903-0, Dresden, Sachsen

Research Site 4905-0, Berlin, Not set

Research Site 4906-0, Berlin, Not set

Research Site 8504-0, Hong Kong, Not set

Research Site 8501-0, Hong Kong, Not set

Research Site 8503-0, Hong Kong, Not set

Research Site 8502-0, Hong Kong, Not set

Research Site 8505-0, Hong Kong, Not set

Research Site 3603-0, Budapest, Not set

Research Site 3606-0, Gyor, Not set

Research Site 3604-0, Kecskemet, Not set

Research Site 3602-0, Salgotarjan, Not set

Research Site 3607-0, Tatabanya, Not set

Research Site 3605-0, Zalaegerszeg, Not set

Research Site 9710-0, Ashdod, Not set

Research Site 9706-0, Haifa, Not set

Research Site 9708-0, Haifa, Not set

Research Site 9702-0, Jerusalem, Not set

Research Site 9707-0, Jerusalem, Not set

Research Site 9703-0, Kfar-Saba, Not set

Research Site 9704-0, Petach-Tikva, Not set

Research Site 9709-0, Ramat-Gan, Not set

Research Site 9705-0, Rehovot, Not set

Research Site 9701-0, Tel Aviv, Not set

Research Site 3908-0, Bergamo, Not set

Research Site 3907-0, Brescia, Not set

Research Site 3901-0, Catania, Not set

Research Site 3903-0, Catanzaro, Not set

Research Site 3906-0, Milano, Not set

Research Site 3911-0, Milano, Not set

Research Site 3904-0, Milano, Not set

Research Site 3909-0, Napoli, Not set

Research Site 3902-0, Pavia, Not set

Research Site 3905-0, Verona, Not set

Research Site 8211-0, Wonju, Gangwon-do

Research Site 8204-0, Seongnam, Gyeonggi-do

Research Site 8201-0, Seoul, Gyeonggi-do

Research Site 8202-0, Suwon, Gyeonggi-do

Research Site 8208-0, Busan, Not set

Research Site 8212-0, Cheonan, Not set

Research Site 8209-0, Incheon, Not set

Research Site 8207-0, Seoul, Not set

Research Site 8213-0, Seoul, Not set

Research Site 8206-0, Seoul, Not set

Research Site 8210-0, Seoul, Not set

Research Site 8203-0, Seoul, Not set

Research Site 8205-0, Seoul, Not set

Research Site 8214-0, Ulsan, Not set

Research Site 4804-0, Krakow, Not set

Research Site 4801-0, Poznan, Not set

Research Site 4802-0, Rzeszów, Not set

Research Site 4807-0, Torun, Not set

Research Site 4805-0, Warszawa, Not set

Research Site 4809-0, Wroclaw, Not set

Research Site 4803-0, Łódź, Not set

Research Site 3403-0, Sant Cugat del Valles, Barcelona

Research Site 3409-0, Santiago de Compostela, La Coruña

Research Site 3406-0, Majadahonda, Madrid

Research Site 3411-0, Pozuelo de Alarcon, Madrid

Research Site 3405-0, Pamplona, Navarra

Research Site 3410-0, Barcelona, Not set

Research Site 3402-0, Barcelona, Not set

Research Site 3404-0, Barcelona, Not set

Research Site 3416-0, Madrid, Not set

Research Site 3407-0, Madrid, Not set

Research Site 3414-0, Madrid, Not set

Research Site 3401-0, Madrid, Not set

Research Site 3418-0, Malaga, Not set

Research Site 3415-0, Málaga, Not set

Research Site 3408-0, Sevilla, Not set

Research Site 3413-0, Sevilla, Not set

Research Site 3417-0, Sevilla, Not set

Research Site 3412-0, Valencia, Not set

Research Site 9001-0, Adana, Not set

Research Site 9002-0, Ankara, Not set

Research Site 9006-0, Ankara, Not set

Research Site 9003-0, Ankara, Not set

Research Site 9004-0, Ankara, Not set

Research Site 9009-0, Diyarbakir, Not set

Research Site 9008-0, Istanbul, Not set

Research Site 9010-0, Izmir, Not set

Research Site 9007-0, Samsun, Not set

Research Site 4404-0, Truro, Cornwall

Research Site 4408-0, London, Greater London

Research Site 4411-0, London, Greater London

Research Site 4406-0, London, Greater London

Research Site 4416-0, London, Greater London

Research Site 4409-0, London, Greater London

Research Site 4402-0, Manchester, Greater Manchester

Research Site 4415-0, Maidstone, Kent

Research Site 4414-0, Bath, Somerset

Research Site 4410-0, Cardiff, South Glamorgan

Research Site 4405-0, Glasgow, Strathclyde

Research Site 4416-A, Sutton, Surrey

Research Site 4407-0, Leeds, West Yorkshire

Research Site 4403-0, Middlesex, Not set

Research Site 4401-0, Nottingham, Not set

Conditions: Metastatic Breast Cancer

Learn More ›

Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation

NCT05696626

Recruiting

The goal of this clinical trial is to assess the efficacy, safety and tolerability of the combination of lasofoxifene and abemaciclib compared to fulvestrant and abemaciclib for the treatment of pre- and postmenopausal women and men who have previously received ribociclib or palbociclib-based treatment and have locally advanced or metastatic estrogen receptor positive (ER+)/human epidermal growth factor 2 negative (HER2-) breast cancer with an estrogen receptor 1 (ESR1) mutation. The main quest... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/30/2025

Locations: Mayo Clinic - Phoenix, Phoenix, Arizona +173 locations

Mayo Clinic - Phoenix, Phoenix, Arizona

University of Arizona - Cancer Center, Tucson, Arizona

Providence Medical Foundation - Santa Rosa, CA, Santa Rosa, California

Mayo Clinic - Jacksonville, Jacksonville, Florida

Miami Cancer Institute, Miami, Florida

Miami Cancer Institute Plantation, Plantation, Florida

Emory University School of Medicine, Atlanta, Georgia

Norton Cancer Institute, Louisville, Kentucky

Johns Hopkins Kimmel Cancer Center, Baltimore, Maryland

Massachusetts General Hospital, Boston, Massachusetts

Dana-Farber Cancer Institute, Boston, Massachusetts

Beth Israel Deaconess Medical Center, Boston, Massachusetts

Cancer and Hematology Centers of Western Michigan, Grand Rapids, Michigan

Allina Health System DBA Virginia Piper Cancer Institute, Minneapolis, Minnesota

Mayo Clinic - Rochester, Rochester, Minnesota

Saint Luke's Cancer Institute, Kansas City, Missouri

Washington University School of Medicine, Saint Louis, Missouri

Renown Regional Medical Centre, Reno, Nevada

New Jersey Cancer Care, PA, Belleville, New Jersey

The Blavatnik Family - Chelsea Medical Center at Mount Sinai, New York, New York

Icahn School of Medicine at Mount Sinai, New York, New York

David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center, New York, New York

Duke University Medical Center, Durham, North Carolina

Altru Health Systems, Grand Forks, North Dakota

The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solovev Research Institute (OSUCCC - James), Columbus, Ohio

University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania

Lyndon B. Johnson Hospital, Houston, Texas

Baylor College of Medicine, Houston, Texas

MD Anderson Cancer Center, Houston, Texas

Harris Health System - Smith Clinic, Houston, Texas

Blacktown Hospital, Blacktown, Not set

Concord Repatriation General Hospital, Concord, Not set

Mater Misericordiae Ltd, South Brisbane, South Brisbane, Not set

Cliniques Universitaires Saint-Luc, Brussels, Not set

Antwerp University Hospital (UZA), Edegem, Not set

Universitaire Ziekenhuizen Leuven, Leuven, Not set

CHU UCL Namur - Site De Sainte-Elisabeth, Namur, Not set

The Ottawa General Hospital, Ottawa, Ontario

Sunnybrook Health Sciences Centre -Bayview Campus, Toronto, Ontario

Hospital Maisonneuve-Rosemont, Montréal, Quebec

Lady Davis Institute for Medical Research Jewish General Hospital, Montréal, Quebec

CIUSSS du Saguenay-Lac-Saint-Jean, Saguenay, Quebec

Anhui Provincial Cancer Hospital, Anhui, Not set

Beijing Cancer Hospital, Beijing, Not set

The First Affiliated Hospital of Bengbu Medical University, Bengbu, Not set

The First Hospital of Jilin University, Changchun, Not set

The Second Xiangya Hospital of Central South University, Changsha, Not set

Sichuan Provincial People's Hospital, Chengdu, Not set

West China Hospital, Sichuan University, Chengdu, Not set

The First Affiliated Hospital, Chongqing Medical University, Chongqi, Not set

The Second Hospital of Dalian Medical University, Dalian, Not set

Deyang People's Hospital, Deyang, Not set

Fuyang Cancer Hosptial, Fuyang, Not set

Fujian Cancer Hospital, Fuzhou, Not set

Fujian Medical University Union Hospital, Fuzhou, Not set

Zhujiang Hospital of Nanfang Medical University, Guandong, Not set

Guangdong Provincial People's Hospital, Guangdong, Not set

Meizhou People's Hospital, Guangdong, Not set

Peking University Shenzhen Hospital, Guangdong, Not set

Sun Yat-Sen University- Cancer Center, Guangdong, Not set

Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Not set

The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Not set

Zhejiang Provincial Hospital of Chinese Medicine, Hangzhou, Not set

Hebei Medical University - The Fourth Hospital - Hebei Provincial Tumor Hospital, Hebei, Not set

Xiangyang Central Hospital, Hubei, Not set

Xiangya Hospital Central South University, Hunan, Not set

Shandong Province Tumor Hospital, Jinan, Not set

Gansu Provincial Hospital, Lanzhou, Not set

The First Hospital of Lanzhou University, Lanzhou, Not set

Linyi Cancer Hospital, Linyi, Not set

The First Affiliated Hospital of Henan University of Science and Technology, Luoyang, Not set

The Affiliated Hospital of Southwest Medical University (Luzhou Medical College), Luzhou, Not set

Jiangxi Cancer Hospital, Nanchang, Not set

Nangchang People's Hospital, Nanchang, Not set

Nanjing Drum Tower Hospital, Nanjing, Not set

Guangxi Medical University Cancer Hospital, Nanning, Not set

Nanyang Central Hospital, Nanyang, Not set

The Second People's Hospital of Neijiang, Neijiang, Not set

Ningbo Medical Center Li Huili Hospital, Ningbo, Not set

Qingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao, Not set

The Affiliated Hospital of Qingdao University, Qingdao, Not set

Fudan University Cancer Center, Shang'ai, Not set

First Affiliated Hospital of Xi'an Jiaotong University, Shanxi, Not set

The Central Hospital of Shaoyang, Shaoyang, Not set

Liaoning Cancer Hospital & Institute, Shenyang, Not set

Yuebei People's Hospital, Shouguang, Not set

University of Electonic Science & Technology (UESTC) - Sichuan Cancer Hospital & Institute, Sichuan, Not set

Tianjin Cancer Hospital Airport Hospital, Tianjin, Not set

Tianjin Medical University Cancer Institute & Hospital, Tianjin, Not set

The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Not set

Hubei Cancer Hospital, Wuhan, Not set

Union Hospital Tongji Medical College Huazhong University of Science and Technolog, Wuhan, Not set

The First Affiliated Hospital of Air Force Medical University, XI Ail, Not set

The first affiliated hospital of Xiamen University, Xiamen, Not set

Xuzhou Central Hospital, Xuzhou, Not set

Yuncheng Central Hospital, Yuncheng, Not set

Zhejiang cancer hospital, Zhejiang, Not set

Zhejiang Provincial People's Hospital, Zhejiang, Not set

Henan Cancer Hospital, Zhengzhou, Not set

The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Not set

Zhongshan City People's Hospital, Zhongshan, Not set

Zhumadian Central Hospital, Zhumadian, Not set

The Affiliated Cancer Hospital of Xinjiang Medical University, Ürümqi, Not set

Service d'Oncologie Medicale - CHRU Besancon, Besançon, Not set

Institut Bergonie, Bordeaux, Not set

Centre Francois Baclesse, CAEN Cedex 05, Not set

Centre Oscar Lambret, Lille, Not set

Centre Leon Berard, Lyon, Not set

Institut Paoli-Calmettes, Marseille, Not set

CHU Poitiers - Pole Regional de Cancerologie de Poitiers (PRC), Poitiers, Not set

Centre Henri Becquerel, Rouen, Not set

Institut Claudius Regaud, Toulouse, Not set

Universitaetsklinikum Carl Gustav Carus Dresden, Dresden, Not set

Klinikum rechts der Isar der Technischen Universitaet Muenchen, München, Not set

Rambam Health Care Campus, Haifa, Not set

Hadassah Ein-Karem Medical Center, Jerusalem, Not set

Shaare Zedek Medical Center, Jerusalem, Not set

Rabin MC, Petach Tikva, Not set

Kaplan Medical Center, Reẖovot, Not set

Tel Aviv Sourasky Medical Center, Tel Aviv, Not set

Sheba Medical Center, Tel HaShomer, Not set

Centro Riferimento Oncologico - Aviano, Aviano, Not set

IRCCS Istituto Romagnolo per lo Studio dei Tumori Dino Amadori - IRST S.r.l., Meldola, Not set

Istituto Europeo di Oncologia, Milano, Not set

Humanitas Istituto Clinico Catanese, Misterbianco, Not set

Azienda Ospedaliero-Universitaria di Modena, Modena, Not set

Istituto Nazionale Tumori IRCCS Fondazione G. Pascale, Napoli, Not set

Azienda Ospedaliero Universitaria di Parma, Parma, Not set

Fondazione IRCCS Policlinico San Matteo, Pavia, Not set

Fondazione Policlinico Universitario A. Gemelli IRCCS - Universita Cattolica del Sacro Cuore, Roma, Not set

Azienda Ospedaliera Universitaria Integrata Verona-Ospedale Borgo Trento, Verona, Not set

National Cancer Center, Gyeonggi-do, Not set

Chonnam National University Hwasun Hospital, Hwasun, Not set

Asan Medical Center, Seoul, Not set

Korea University Anam Hospital, Seoul, Not set

Severance Hospital, Yonsei University Health System, Seoul, Not set

KO - MED Centra Kliniczne Sp. z o.o., Wojewodzki Szpital Specjalistyczny w Bialej Podlaskiej, Biała Podlaska, Not set

Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy, Oddzial w Gliwicach, I Klinika Radioterapii i Chemioterapii, Gliwice, Not set

Szpital Specjalistyczny im. Ludwika Rydygiera w Krakowie - Oddzial Onkologii Klinicznej z Pododdzialem Dziennym, Krakow, Not set

SP ZOZ Szpital Uniwersytecki w Krakowie, Oddzial Onkologii Klinicznej, Kraków, Not set

Uniwersytecki Szpital Kliniczny w Poznaniu, Oddzial Chemioterapii, Poznań, Not set

Wielkopolskie Centrum Onkologii (WCO) / The Greater Poland Cancer Center, Poznań, Not set

Mazowiecki Szpital Onkologiczny, Wieliszew, Not set

Instytut Centrum Zdrowia Matki Polki - Klinika Onkologii, Łódź, Not set

Centrul Medical Focus, Bucharest, Not set

Radiotherapy Center Cluj, Cluj-Napoca, Not set

Onco Clinic Consult SA, Craiova, Not set

Oncology Center Sfantul Nectarie, Craiova, Not set

Gral Medical SRL, Piteşti, Not set

OncoMed Oncology Center, Timişoara, Not set

National Cancer Centre Singapore, Singapore, Not set

Curie Oncology, Singapore, Not set

Hospital Clinic Barcelona, Barcelona, Not set

Hospital Universitario Vall d'Hebron, Barcelona, Not set

Hospital Universitario Reina Sofia, Córdoba, Not set

Clinica Universidad de Navarra - Madrid, Madrid, Not set

Hospital Beata Maria Ana, Madrid, Not set

Hospital General Universitario Gregorio Maranon, Madrid, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

Hospital Universitario de La Princesa, Madrid, Not set

Hospital Regional Universitario de Malaga, Málaga, Not set

Clinica Universidad de Navarra - Pamplona, Pamplona, Not set

Instituto Valenciano de Oncologia, Valencia, Not set

Changhua Christian Hospital (CCH), Changhua, Not set

Kaohsiung Medical University Chung-Ho Memorial Hospital (KMUH), Kaohsiung, Not set

National Cheng Kung University Hospital, Tainan, Not set

Tri-Service General Hospital, Taipei City, Not set

Koo Foundation Sun Yat-Sen Cancer Center, Taipei, Not set

National Taiwan University Hospital, Taipei, Not set

Linkou Chang Gung Memorial Hospital (CGMHLK), Taoyuan City, Not set

Leeds Teaching Hospitals NHS Trust, Leeds, Not set

Charing Cross Hospital, London, Not set

The Christie NHS Foundation Trust, Manchester, Not set

Nottingham City Hospital, Nottingham, Not set

Conditions: Metastatic Breast Cancer

Learn More ›

OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer

NCT06016738

Recruiting

This phase 3 clinical trial compares the safety and efficacy of palazestrant (OP-1250) to the standard-of-care options of fulvestrant or an aromatase inhibitor in women and men with breast cancer whose disease has advanced on one endocrine therapy in combination with a CDK4/6 inhibitor.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/23/2025

Locations: Clinical Trial Site, Tucson, Arizona +173 locations

Clinical Trial Site, Tucson, Arizona

Clinical Trial Site, Fountain Valley, California

Clinical Trial Site, La Jolla, California

Clinical Trial Site, Los Angeles, California

Clinical Trial Site, Whittier, California

Clinical Trial Site, Aurora, Colorado

Clinical Trial Site, Denver, Colorado

Clinical Trial Site, Golden, Colorado

Clinical Trial Site, Grand Junction, Colorado

Clinical Trial Site, Danbury, Connecticut

Clinical Trial Site, Newark, Delaware

Clinical Trials Site, Jacksonville, Florida

Clinical Trial Site, Margate, Florida

Clinical Trial Site, Orlando, Florida

Clinical Trial Site, Plantation, Florida

Clinical Trial Site, Tamarac, Florida

Clinical Trial Site, Atlanta, Georgia

Clinical Trial Site, Chicago, Illinois

Clinical Trial Site, Urbana, Illinois

Clinical Trial Site, Baton Rouge, Louisiana

Clinical Trial Site, Baltimore, Maryland

Clinical Trial Site, Boston, Massachusetts

Clinical Trial Site, St Louis Park, Minnesota

Clinical Trial Site, Lincoln, Nebraska

Clinical Trial Site, Farmington, New Mexico

Clinical Trial Site, New York, New York

Clinical Trial Site, Port Jefferson Station, New York

Clinical Trial Site, Dayton, Ohio

Clinical Trial Site, Toledo, Ohio

Clinical Trial Site, Portland, Oregon

Clinical Trial Site, Nashville, Tennessee

Clinical Trial Site, Dallas, Texas

Clinical Trial Site, Houston, Texas

Clinical Trial Site, Spokane, Washington

Clinical Trial Site, San Salvador De Jujuy, Jujuy

Clinical Trial Site, Viedma, Río Negro

Clinical Trial Site, Rosario, Santa Fe

Clinical Trial Site, San Miguel De Tucumán, Tucumán

Clinical Trial Site, Buenos Aires, Not set

Clinical Trial Site, Córdoba, Not set

Clinical Trial Site, La Rioja, Not set

Clinical Trial Site, Gosford, New South Wales

Clinical Trial Site, Westmead, New South Wales

Clinical Trial Site, Adelaide, South Australia

Clinical Trial Site, Ballarat Central, Victoria

Clinical Trial Site, Clayton, Victoria

Clinical Trial Site, Shepparton, Victoria

Clinical Trial Site, Nedlands, Western Australia

Clinical Trial Site, Edegem, Antwerpen

Clinical Trial Site, Woluwe-Saint-Lambert, Brussels

Clinical Trial Site, Charleroi, Hainaut

Clinical Trial Site, Leuven, Vlaams Brabant

Clinical Trial Site, Salvador, Bahia

Clinical Trial Site, Belo Horizonte, Minas Gerais

Clinical Trial Site, Recife, Pernambuco

Clinical Trial Site, Porto Alegre, Rio Grande do Sul

Clinical Trial Site, Itajaí, Santa Catarina

Clinical Trial Site, Sorocaba, São Paulo

Clinical Trial Site, Rio De Janeiro, Not set

Clinical Trial Site, Panagyurishte, Pazardzhik

Clinical Trial Site, Sofia, Sofia-Grad

Clinical Trial Site, Vratsa, Not set

Clinical Trial Site, Calgary, Alberta

Clinical Trial Site, Montréal, Quebec

Clinical Trial Site, Hradec Králové, Královéhradecký kraj

Clinical Trial Site, Nový Jičín, Moravskoslezský kraj

Clinical Trial Site, Olomouc, Olomoucký kraj

Clinical Trial Site, Bourg-en-Bresse, Ain

Clinical Trial Site, Besançon, Doubs

Clinical Trial Site, Nantes, Loire-Atlantique

Clinical Trial Site, Compiègne, Oise

Clinical Trial Site, Clermont-Ferrand, Puy-de-Dôme

Clinical Trial Site, Le Mans, Sarthe

Clinical Trial Site, Villejuif, Val-de-Marne

Clinical Trial Site, Montpellier, Not set

Clinical Trial Site, Karlsruhe, Baden-Württemberg

Clinical Trial Site, Krefeld, Nordrhein-Westfalen

Clinical Trial Site, Velbert, Nordrhein-Westfalen

Clinical Trial Site, Dresden, Sachsen

Clinical Trial Site, Central, Not set

Clinical Trial Site, Hong Kong, Not set

Clinical Trials Site, Hong Kong, Not set

Clinical Trial Site, Kowloon, Not set

Clinical Trial Site, Pécs, Baranya

Clinical Trial Site, Kecskemét, Bács-Kiskun

Clinical Trial Site, Debrecen, Hajdú-Bihar

Clinical Trial Site, Avellino, Campania

Clinical Trial Site, Bologna, Emilia-Romagna

Clinical Trial Site, Meldola, Emilia-Romagna

Clinical Trial Site, Modena, Emilia-Romagna

Clinical Trial Site, Reggio Emilia, Emilia-Romagna

Clinical Trial Site, Udine, Friuli-Venezia Giulia

Clinical Trial Site, Roma, Lazio

Clinical Trial Site, Milano, Lombardia

Clinical Trial Site, Rozzano, Lombardia

Clinical Trial Site, Alessandria, Piemonte

Clinical Trial Site, Pavia, Not set

Clinical Trial Site, Suwon-si, Gyeonggi-do

Clinical Trial Site, Busan, Not set

Clinical Trial Site, Seoul, Not set

Clinical Trial Site, Suwon, Not set

Clinical Trials Site, Sungai Petani, Kedah

Clinical Trial Site, Kota Bharu, Kelantan

Clinical Trial Site, George Town, Penang

Clinical Trial Site, Ipoh, Perak

Clinical Trial Site, Putrajaya, Putramya

Clinical Trial Site, Kuching, Sarawak

Clinical Trial Site, Petaling Jaya, Selangor

Clinical Trial Site, Kuala Lumpur, WP

Clinical Trial Site, Zapopan, Jalisco

Clinical Trial Site, Monterrey, Not set

Clinical Trial Site, Oaxaca, Not set

Clinical Trial Site, Sinaloa, Not set

Clinical Trial Site, Rotterdam, Zuid-Holland

Clinical Trial Site, Łódź, Lódzkie

Clinical Trial Site, Otwock, Mazowieckie

Clinical Trial Site, Brzozów, Podkarpackie

Clinical Trial Site, Rzeszów, Podkarpackie

Clinical Trial Site, Gdynia, Pomorskie

Clinical Trial Site, Skórzewo, Wielkopolskie

Clinical Trial Site, Wrocław, Not set

Clinical Trial Site, Matosinhos, Porto

Clinical Trial Site, Coimbra, Not set

Clinical Trial Site, Lisboa, Not set

Clinical Trial Site, Porto, Not set

Clinical Trial Site, Mayaguez, Not set

Clinical Trial Site, Oradea, Bihor

Clinical Trial Site, București, Bucuresti

Clinical Trial Site, Cluj-Napoca, Cluj

Clinical Trial Site, Craiova, Dolj

Clinical Trial Site, Timisoara, Timis

Clinical Trial Site, Brașov, Not set

Clinical Trial Site, Iași, Not set

Clinical Trial Site, Pamplona, Navarra

Clinical Trial Site, Alicante, Not set

Clinical Trial Site, Badajoz, Not set

Clinical Trial Site, León, Not set

Clinical Trial Site, Lleida, Not set

Clinical Trial Site, Madrid, Not set

Clinical Trial Site, Santiago De Compostela, Not set

Clinical Trial Site, Valencia, Not set

Clinical Trial Site, Changhua, Not set

Clinical Trial Site, Kaohsiung, Not set

Clinical Trial Site, Taichung, Not set

Clinical Trial Site, Tainan City, Not set

Clinical Trial Site, Taipei city, Not set

Clinical Trial Site, Taipei, Not set

Clinical Trial Site, Bangkok, Not set

Clinical Trial Site, Chiang Mai, Not set

Clinical Trial Site, Samut Sakhon, Not set

Clinical Trial Site, Songkhla, Not set

Clinical Trial Site, London, Not set

Conditions: Breast Cancer, Advanced Breast Cancer, Metastatic Breast Cancer, ER Positive Breast Cancer, HER2 Negative Breast Carcinoma

Learn More ›

Integrated Patient Avatars for Guiding Systemic Therapy Treatments in Metastatic Breast Cancer Patients

NCT04608357

Recruiting

The investigators propose to use clinically validated patient avatar technology ("PDXovo") that can test multiple drugs against patients' cancers to identify the most promising systemic therapy for each individual.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

01/17/2025

Locations: Sunnybrook Health Sciences Centre, Toronto, Ontario

Conditions: Breast Cancer, Breast Neoplasms, Metastatic Breast Cancer, Cancer, Breast

Learn More ›

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