There are currently 5 active clinical trials seeking participants for Neuropathic Pain research studies. The states with the highest number of trials for Neuropathic Pain participants are .
Effects of LY3848575 Versus Placebo in Participants With Painful Distal Sensory Polyneuropathy
NCT06568042
Recruiting
The purpose of this study is to evaluate how safe and how well a treatment works compared to placebo for people with nerve pain that begins in their feet and moves up the leg to just below the knee. Participation may last up to 30 weeks including screening.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/22/2025
Locations: MD First Research - Chandler, Chandler, Arizona +80 locations
Conditions: Neuropathic Pain, Distal Sensory Polyneuropathy
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Implementation of the Pain and Irritability of Unknown Origin (PIUO) Pathway in Community Pediatric Practices
NCT06869928
Recruiting
The Pain and Irritability of Unknown Origin (PIUO) Pathway is a clinical pathway that was developed to evaluate and manage unexplained pain and irritability for children with severe neurological impairments (SNI) who cannot verbally communicate 'where it hurts'. The investigators studied the usefulness of the Pathway with families and expert clinicians in 4 centres across Canada. The aim of this Phase 2 study is to determine whether this tool can transfer from hospital research centres into the... Read More
Gender:
ALL
Ages:
Between 6 months and 18 years
Trial Updated:
03/05/2025
Locations: BC Children's Hospital, Vancouver, British Columbia
Conditions: Pain, Irritability, Neuropathic Pain
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Mechanisms and Outcome-Prognostication for Paresthesia-based and -free Spinal Cord Stimulation
NCT03852381
Recruiting
Spinal cord stimulation (SCS) relies on stimulation of pain-relieving pathways in the spinal cord to treat chronic neuropathic pain. Traditional paresthesia-based SCS (PB-SCS) relies on providing analgesia through stimulation of spinal cord dorsal columns but it is often associated with attenuation of analgesic benefit and lack of acceptance of paresthesias. Recently introduced three different paresthesia-free (PF-SCS) modes of stimulation aim to overcome limitations of PB-SCS. Several questions... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
12/03/2024
Locations: Toronto Western Hospital, Toronto, Ontario
Conditions: Neuropathic Pain, Chronic Pain
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Psychotherapy for Ketamine's Enhanced Durability in Chronic Neuropathic Pain: A Randomized Controlled Pilot Trial
NCT05639322
Recruiting
The purpose of the study is to investigate new therapies to alleviate pain on neuropathic chronic pain. At this time, the main purpose is to complete a feasibility or pilot study with 60 participants suffering from neuropathic chronic pain. Participants will be randomized to (1) Ketamine (Hydrochloride) HCL; (2) psychotherapy (using Cognitive Behavioral Therapy); or (3) a combination of Ketamine HL and psychotherapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/12/2024
Locations: St. Michael's Hospital, Toronto, Ontario
Conditions: Neuropathic Pain
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Efficacy of Gabapentin in Treating Pain in Children With SNI (Gabapentin Trial)
NCT04619862
Recruiting
Children born with severe brain-based developmental disabilities frequently experience persistent unexplained periods of pain and irritability, often compounded by a limited capacity to communicate their distress. The investigators call this entity Pain and Irritability of Unknown Origin (PIUO). The rationale of this trial is to identify the clinical effect size of gabapentin in reducing and resolving pain in children with developmental brain disorders, specifically those with severe neurologica... Read More
Gender:
ALL
Ages:
Between 6 months and 18 years
Trial Updated:
05/06/2024
Locations: BC Children's Hospital, Vancouver, British Columbia
Conditions: Pain, Neuropathic Pain, Irritability
Register for Updates