There are currently 36 active clinical trials seeking participants for Stroke research studies. The states with the highest number of trials for Stroke participants are .
The Whole Day Matters After Stroke (BIG-STEPS)
NCT05753761
Recruiting
Goal of research program: To understand person-specific factors, such as imaging markers and activity patterns early after stroke, that may guide precision rehabilitation to optimize function and improve recovery. Objectives: 1. Test the effect of reducing sedentary behaviour early after stroke on functional mobility and global disability outcomes. 2. Determine the impact of neuroimaging biomarkers (e.g. leukoaraiosis) on response to rehabilitation. 3. Explore the predictive value of accelerom... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/14/2025
Locations: University of Alberta Hospital, Edmonton, Alberta
Conditions: Stroke
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Transcutaneous Spinal Cord Stimulation for Upper Extremity Function
NCT06596369
Recruiting
Transcutaneous electrical stimulation (tcES) of the spinal cord has shown great promise in restoring upper extremity function after spinal cord injury (SCI). More recently, the use of invasive, epidural electrical stimulation of the spinal cord has also demonstrated promise in restoring upper extremity function post-stroke. However, the effect of stimulation parameters such as electrode configuration and stimulation frequency on excitability of the nervous system remains unknown preventing the o... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
03/24/2025
Locations: Glenrose Rehabilitation Hospital, Edmonton, Alberta +1 locations
Conditions: Spinal Cord Injuries, Stroke
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Standardized Goal-Directed Vs. Self-Directed Valsalva Maneuver for the Assessment of Patent Foramen Ovale
NCT06670781
Recruiting
Ischemic stroke represents a major public health issue, leading to significant disabilities and deaths worldwide. When no clear cause for stroke is found following a comprehensive cardiovascular evaluation (no atrial fibrillation, cardiac masses, or atherosclerosis) i.e. cryptogenic stroke, it is recommended to search for a patent foramen ovale (PFO), especially in young patients. It is estimated that cryptogenic stroke accounts for 30% to 40% of ischemic strokes. Transthoracic echocardiography... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/24/2025
Locations: University of Ottawa Heart Institute, Ottawa, Ontario +1 locations
Conditions: Stroke
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Virtual Physical Activity Seated Exercise - Phase 2
NCT05724823
Recruiting
This study will determine the acceptability of delivering seated exercises online and if seated exercises can improve balance, mobility, quality of life, and cardiometabolic health in those living with a stroke related mobility impairment. Participants will be allocated to either a 10-week seated exercise program or a delayed 2-week Boot Camp program. All seated exercises sessions and assessments will be conducted virtually.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/05/2025
Locations: GF Strong Rehabilitation Centre, Vancouver, British Columbia +4 locations
Conditions: Stroke, Chronic Stroke, Stroke, Ischemic, Stroke Hemorrhagic
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Amplatzer Amulet LAAO Vs. NOAC
NCT04226547
Recruiting
The objective of this trial is to evaluate the safety and effectiveness of the Amulet LAA occluder compared to NOAC therapy in patients with non-valvular AF at increased risk for ischemic stroke and who are recommended for long-term NOAC therapy. The clinical investigation is a prospective, randomized, multicenter active control worldwide trial. Subjects will be randomized in a 1:1 ratio between the Amulet LAA occlusion device ("Device Group") and a commercially available NOAC medication ("Cont... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/25/2025
Locations: University Hospital - Univ. of Alabama at Birmingham (UAB), Birmingham, Alabama +131 locations
Conditions: Atrial Fibrillation, Stroke, Bleeding
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Comparative Study of the Effects of Dry Needling and Botulinum Toxin Type a As a Treatment for Lower Limb Post-stroke Spasticity
NCT06296082
Recruiting
This is a randomized parallel group clinical trial which will be conducted in three countries (Spain, Canada and Belgium) comparing Botulinum Toxin type A (BTX-A) and Dry Needling (DN) effectiveness for post-stroke spasticity in participants who had a first stroke in the previous 12 months and have plantar flexor spasticity. Participants will be randomly allocated to receive either one session of BTX-A or 12 weekly sessions of DN. Blinded evaluators will assess the effects before, during, and af... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
02/17/2025
Locations: Universiteit Antwerpen, Antwerpen, Flandes +2 locations
Conditions: Stroke
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Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG
NCT04045665
Recruiting
The primary objective of this study is to evaluate the effectiveness (prevention of thromboembolic events) and safety (major bleeding) of adding oral anticoagulation (OAC) to background antiplatelet therapy in patients who develop new-onset post-operative atrial fibrillation (POAF) after isolated coronary artery bypass graft (CABG) surgery. All patients with a qualifying POAF event, who decline randomization, will be offered the option of enrollment in a parallel registry that captures their ba... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/05/2025
Locations: CHI St. Vincent, Arkansas, Little Rock, Arkansas +95 locations
Conditions: Atrial Fibrillation, Stroke, Bleeding
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Optimal Intensity of Reactive Balance Training Post-stroke
NCT06555016
Recruiting
Falls in daily life are a serious risk for people with stroke. A new type of balance training, called reactive balance training (RBT). may help to reduce this risk of falling. In some previous studies participants improved their balance reactions a lot after RBT, whereas others did not improve at all. These studies used different types and amounts of training. Differences in training program features might explain differences in the study results. Training intensity is the difficulty or challen... Read More
Gender:
ALL
Ages:
20 years and above
Trial Updated:
01/22/2025
Locations: Toronto Rehabilitation Institute, Toronto, Ontario
Conditions: Accidental Fall, Stroke
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Stroke Thrombectomy and Aneurysm Registry
NCT04994756
Recruiting
This international multi-center registry is used to collect existing information and outcomes for patients undergoing an operation for treatment of injuries to the brain including the blockage of blood flow to an area of the brain, an abnormal ballooning of an artery, abnormal tangling of blood vessels, abnormal formation of blood vessels, tearing of vein, and bleeding in the brain. This information is used to help predict outcomes that undergo an operation for treatment of the above-listed brai... Read More
Gender:
ALL
Ages:
Between 1 year and 120 years
Trial Updated:
12/05/2024
Locations: University of Arizona, Tucson, Arizona +62 locations
Conditions: Stroke, Thromboses, Intracranial, Aneurysm, Brain
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COgnitive-somatoSensory-MOtor Training to Improve Arm and Hand Function After Stroke (iCOSMO)
NCT06498011
Recruiting
The iCOSMO study investigates the feasibility and beneficial effects of an intervention combining sensation, motor and cognition to improve arm and hand function after chronic stroke.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/05/2024
Locations: Toronto Rehabilitation Institute, Toronto, Ontario
Conditions: Stroke, CVA, Cerebrovascular Accident
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Virtual Reality and Field Training to Enhance Community Walking After Stroke
NCT04559373
Recruiting
While stroke survivors discharged from rehabilitation present with some recovery in mobility, their ability to ambulate in the community remains limited. The investigators propose to test a novel, low-cost, intensive and individually tailored intervention that combines virtual reality (VR) and field training to enhance community ambulation and participation in stroke survivors discharged from rehabilitation. The aims are to: (1) Assess feasibility, acceptability, safety and adherence of the int... Read More
Gender:
ALL
Ages:
Between 40 years and 74 years
Trial Updated:
11/20/2024
Locations: Jewish Rehabilitation Hospital, Laval, Quebec +1 locations
Conditions: Stroke
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Playing Piano to Improve Hand Function Early After Stroke
NCT06621771
Recruiting
The goal of this clinical trial is to study the feasibility of a 6-week piano playing training intervention in a subacute stroke population. More specifically, the investigators aim to (1) implement and test the feasibility of the intervention in the subacute stroke rehabilitation program; and (2) explore the acceptability of the supervised training sessions and home practice sessions. Researchers will also (3) estimate and contrast the effects of the piano training intervention as compared to c... Read More
Gender:
ALL
Ages:
Between 40 years and 74 years
Trial Updated:
11/20/2024
Locations: Jewish Rehabilitation Hospital, Laval, Quebec
Conditions: Stroke
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