There are currently 36 active clinical trials seeking participants for Stroke research studies. The states with the highest number of trials for Stroke participants are .
Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis
NCT05047172
Recruiting
The primary goal of the trial is to determine if the experimental arms (rivaroxaban or ticagrelor or both) are superior to the clopidogrel arm for lowering the 1-year rate of ischemic stroke, intracerebral hemorrhage, or vascular death.
Gender:
ALL
Ages:
30 years and above
Trial Updated:
08/06/2025
Locations: University of Alabama Hospital, Birmingham, Alabama +124 locations
Conditions: Intracranial Arteriosclerosis, Stroke
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Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)
NCT05065216
Recruiting
This is a Phase 2/3 study evaluating the safety and efficacy of DM199 (rinvecalinase alfa) in treating participants with moderate stroke severity, who present within 24 hours of Acute Ischemic Stroke (AIS) onset due to small and medium vessel occlusions. This study focuses on participants with limited treatment options. Participants who have or will receive mechanical thrombectomy (MT) are not eligible for participation. Additionally, participants who have received fibrinolytics are excluded unl... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
07/24/2025
Locations: Gulf Health Hospitals d/b/a Thomas Hospital, Fairhope, Alabama +37 locations
Conditions: Acute Stroke, Ischemic Stroke, Stroke
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The Effect of Targeting the Plantaris Muscle-tendon in Surgical Correction of Ankle Equinus in Children
NCT07090057
Recruiting
Tight ankle muscles can produce ankle equinus (limited ability to pull the foot upward) and occur often in children, significantly impacting their ability to walk. If not treated, children with ankle equinus frequently experience reduced function and long-term foot problems, such as pain. Currently, treatment options include surgery or Botulinum toxin (BoNTA) injection into the large calf muscles that point the foot downwards, aiming to reduce their tightness. However, these treatments can be le... Read More
Gender:
ALL
Ages:
Between 4 years and 17 years
Trial Updated:
07/22/2025
Locations: Stollery Children's Hospital, Edmonton, Alberta
Conditions: Idiopathic Toe Walking, Cerebral Palsy, Hereditary Spastic Paraparesis, Traumatic Brain Injury, Spinal Cord Injury, Spinal Cord Tethering, Stroke, Hereditary Sensory-motor Neuropathy
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Stimulating Postural Control to Augment Rehabilitation After Cerebral Stroke (SPARC): a Pilot Trial
NCT06987682
Recruiting
People living with stroke have a high risk of falling and this risk increases as mobility improves over the first year post-stroke. Despite the high number of falls, there is a lack of interventions to prevent falls after stroke. One possible solution is to alter nerve activity through delivery of a stimulus, such as electrical stimulation. The purpose of this study is to test the study plan and to find out whether enough participants will join a larger study and accept the study procedures of c... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/17/2025
Locations: KITE Research Institute, Toronto Rehabilitation Institute - University Health Network, Toronto, Ontario
Conditions: Stroke
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The Active Transition Home Post-Stroke Program
NCT06119230
Recruiting
Post-stroke participants will wear wearable sensors for one week at 1-week prior to discharge from inpatient rehabilitation, 3- and 7- weeks post-discharge and 3-months post-discharge. All participants will wear sensors but only participants in the intervention group will receive sensor-informed activity feedback (e.g., activity, sleep and sedentary behaviour) and feedback informed goal setting sessions with a physiotherapist. The feedback forms will be co-created with physiotherapists working a... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/15/2025
Locations: GF Strong Rehabilitation Centre, Vancouver, British Columbia
Conditions: Stroke
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Using Omnidirectional Virtual Reality and Treadmill Training for Chronic Stroke
NCT06495450
Recruiting
The primary objective of this pilot randomized controlled trial (RCT) is to test the feasibility (recruitment rate, retention rate, participant burden, adherence, technical issues, safety) and usability (system usability scale, SUS) of Omnidirectional treadmill Virtual Reality training (omni-VR) among chronic stroke survivors. Our secondary objective is to (1) estimate the extent to which cognition, brain activation during a dual task activity, walking ability, and dynamic balance change after 3... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/20/2025
Locations: Nova Scotia Rehabilitation & Arthritis Centre, Halifax, Nova Scotia
Conditions: Stroke
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Anticoagulation for Stroke Prevention In Patients With Recent Episodes of Perioperative AF After Noncardiac Surgery
NCT03968393
Recruiting
Multinational, investigator-initiated study of oral anticoagulation versus no anticoagulation for the prevention of stroke and other adverse cardiovascular events in patients with transient perioperative atrial fibrillation after noncardiac surgery and additional stroke risk factors.
Gender:
ALL
Ages:
55 years and above
Trial Updated:
06/10/2025
Locations: Cedars-Sinai Medical Center, Los Angeles, California +104 locations
Conditions: Stroke, Atrial Fibrillation
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International Care Bundle Evaluation in Cerebral Hemorrhage Research
NCT06429332
Recruiting
Spontaneous intracerebral haemorrhage (ICH) accounts for approximately 10-15% of all strokes but stands for 50% of stroke-related morbidity and mortality. Approximately half of all patients with ICH have a decreased level of consciousness at hospital admission. Despite this, intensive care and neurosurgical interventions are uncommon. A study conducted in low- and middle-income countries has demonstrated a beneficial effect of a treatment package consisting of early intensive blood pressure lowe... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/30/2025
Locations: The George Institute for Global Health, Sydney, Not set +13 locations
Conditions: Intracerebral Hemorrhage, Intracerebral Haemorrhage, Intraventricular Hemorrhage, Stroke, Cerebrovascular Disease
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Rise & Shine: Promoting Sleep Quality in Chronic Stroke With Exercise
NCT06847074
Recruiting
health problems, such as heart disease, diabetes, cognitive impairment, and dementia. After a person suffers a stroke, they often experience difficulties in getting a good night's sleep. Approximately half of stroke survivors have insomnia, or have trouble falling and/or staying asleep. Poor sleep quality among stroke survivors increases the risk of recurrent stroke by 3-fold and the risk of early death by 76%. Hence, stroke survivors need strategies to promote better sleep. Fortunately, evide... Read More
Gender:
ALL
Ages:
55 years and above
Trial Updated:
05/28/2025
Locations: Vancouver Coastal Health Research Institute Research Pavilion, Vancouver, British Columbia
Conditions: Stroke, Poor Quality Sleep
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Optimizing Recruitment to Drive Equitable Research Opportunity in Stroke Rehabilitation Trials in Canada
NCT06576089
Recruiting
Stroke is a major health issue in Canada. Stroke affects over 400,000 Canadians, and this number is expected to nearly double by 2038. Research studies in stroke recovery can help us better understand effective rehabilitation treatments and help reduce the burden of stroke. Some groups of people however are commonly not included in stroke studies. For example, it is more common for men to take part in research than women, and people with aphasia (a language impairment commonly seen after stroke)... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/07/2025
Locations: University of Calgary & Foothills Medical Centre, Calgary, Alberta +4 locations
Conditions: Stroke
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Biofeedback for Hemianopia Vision Rehabilitation
NCT05397873
Recruiting
Patients with brain injury secondary to stroke, surgery, or trauma frequently suffer from homonymous hemianopia, defined as vision loss in one hemifield secondary to retro- chiasmal lesion. Classic and effective saccadic compensatory training therapies are current aim to reorganize the control of visual information processing and eye movements or, in other words, to induce or improve oculomotor adaptation to visual field loss. Patients learn to intentionally shift their eyes and, thus, their vis... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
05/05/2025
Locations: Toronto Western Hospital, Toronto, Ontario
Conditions: Hemianopsia, Homonymous, Brain Injury, Stroke, Brain Tumor, Brain Trauma
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Cranial Nerve Neuromodulation to Improve Arm Function and Brain Plasticity in Stroke
NCT06386510
Recruiting
Following a stroke, persistent residual muscle weakness in the upper limb (UL) drastically impacts the individuals' quality of life and level of independence. Training interventions are recommended to promote UL motor recovery, and recent studies have shown that training must be tailored to each individual's recovery potential to maximise training gains. Complementary to training interventions, non-invasive brain stimulation devices (NIBS) can help support the provision of post-stroke care by mo... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
05/02/2025
Locations: CRIR/Feil/Oberfeld Research Center; Centre intégré de santé et de services sociaux de Laval; Jewish Rehabilitation Hospital, Laval, Quebec +2 locations
Conditions: Stroke
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