There are currently 32 active clinical trials seeking participants for Ulcerative Colitis research studies. The states with the highest number of trials for Ulcerative Colitis participants are .
IBD Strong Peer2Peer for Self-Management of Psychological Distress
NCT05722236
Recruiting
Psychological distress (PD) as a result of inflammatory bowel disease (IBD) is prevalent and associated with worse disease-related outcomes. IBD-associated psychological distress (IBD-PD) is particularly common at initial diagnosis, during disease flares, before surgery, and during transitions of care. Access to evidence-based, gold-standard psychological interventions and emotional support for IBD-PD has been identified as a major care gap by persons living with IBD. The COVID-19 pandemic has f... Read More
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
07/08/2025
Locations: QEII Health Sciences Centre, Halifax, N.S.
Conditions: Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn Disease
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Mirikizumab Real World Protocol
NCT06696014
Recruiting
The goal of this observational study is to learn about how effective mirikizumab (Omvoh) is when treating patients with ulcerative colitis (UC) Does mirikizumab (Omvoh) lead to a reduction in symptoms at intervals throughout one year? Participants being prescribed mirikizumab (Omvoh) as part of their regular medical care for UC will answer online survey questions about their bowel habits for 1 year.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/08/2025
Locations: South Denver Gastroenterology, Denver, Colorado +8 locations
Conditions: Ulcerative Colitis
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LFMT vs Placebo in New Biologic Start for Ulcerative Colitis
NCT05327790
Recruiting
To compare the safety and efficacy of concomitant LFMT versus placebo in UC patients who are starting vedolizumab or ustekinumab.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
07/02/2025
Locations: University of Alberta Hospital, Edmonton, Alberta
Conditions: Ulcerative Colitis
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A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Ulcerative Colitis
NCT06254950
Recruiting
The main aim of this study is to learn if TAK-279 reduces bowel inflammation and symptoms compared to placebo. Another aim is to compare any medical problems that participants have when they take TAK-279 or placebo and how well the participants tolerate any problems. The participants will take capsules of either TAK-279 or placebo for up to 3 months (12 weeks). Then all the participants will receive TAK-279 for the rest of the treatment part of the study (1 year or 52 weeks). During the study,... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
06/10/2025
Locations: GastroIntestinal BioSciences, Los Angeles, California +175 locations
Conditions: Ulcerative Colitis
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Personalized Anti-Inflammatory Fibres in Ulcerative Colitis
NCT06515210
Recruiting
The goal of this clinical trial is to determine the clinical effects of two different dietary fibre supplements, acacia gum (AG) and microcrystalline cellulose (MCC), in patients with ulcerative colitis. The main question it aims to answer is: Can the fibre supplements reduce gut inflammation (fecal calprotectin)? Researchers will compare AG and MCC to a placebo (a look-alike substance that contains no fibre) to see if the fibre supplements improve inflammation in ulcerative colitis. Participa... Read More
Gender:
ALL
Ages:
Between 15 years and 60 years
Trial Updated:
06/05/2025
Locations: University of Alberta Hospital, Edmonton, Alberta
Conditions: Ulcerative Colitis
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Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis
NCT06029972
Recruiting
The goal of this study is to learn if tilpisertib fosmecarbil (formerly known as GS-5290) is effective and safe in treating participants with moderate to severe ulcerative colitis. The study will compare participants in different treatment groups treated with tilpisertib fosmecarbil with participants treated with placebo. The primary objective of this study is to demonstrate the efficacy of tilpisertib fosmecarbil, compared to placebo control, in achieving Clinical Response at Week 12.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
05/05/2025
Locations: Arizona Digestive Health, Sun City, Arizona +122 locations
Conditions: Ulcerative Colitis
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Evaluation of the SIMBA Capsule for Small Intestinal Dysbiosis
NCT05633706
Recruiting
The SIMBA Capsule is a small, single-use, ingestible capsule that allows for the non-invasive sampling of small bowel contents using purely mechanical means. The study will compare the microbial and metabolomics analysis from the sample collected with the capsule series, to same-participant symptom questionnaires and stool microbial analysis.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
04/10/2025
Locations: Nimble Science, Calgary, Alberta
Conditions: Irritable Bowel Syndrome, Crohn Disease, Celiac Disease, Ulcerative Colitis, Functional Dyspepsia, Type 2 Diabetes, Healthy
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Personalized B-fructan Diet in Inflammatory Bowel Disease Patients
NCT05615779
Recruiting
This study aims to examine patient tolerability of personalized dietary fibre consumption recommendations (high-pectin diet versus high-B-fructan diet based on personalized responses), provided by an IBD dietician, based on our novel translational research findings.
Gender:
ALL
Ages:
Between 6 years and 39 years
Trial Updated:
04/02/2025
Locations: University of Alberta Hospital, Edmonton, Alberta +1 locations
Conditions: Inflammatory Bowel Diseases, Ulcerative Colitis
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A Study of Efficacy and Safety of Rosnilimab in Subjects with Moderate to Severe Ulcerative Colitis (ROSETTA)
NCT06127043
Recruiting
ROSETTA STUDY: This study will evaluate the safety, tolerability, and efficacy of Rosnilimab in subjects with moderate to severe ulcerative colitis (UC)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/22/2025
Locations: AnaptysBio Investigational Site 10-115, Phoenix, Arizona +99 locations
Conditions: Ulcerative Colitis
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Genome Analysis Across Populations in Inflammatory Bowel Disease
NCT06042387
Recruiting
Objective: To use clinical, genetic and genome analysis to better understand and define the genetic and environmental factors that contribute to IBD within affected populations.
Gender:
ALL
Ages:
All
Trial Updated:
03/20/2025
Locations: Sinai Health System, Toronto, Ontario
Conditions: Ulcerative Colitis, Healthy, Crohn Disease, Inflammatory Bowel Diseases
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Bowel Preparation for Colonoscopy Among Individuals With Crohn's and Ulcerative Colitis Disease.
NCT06298461
Recruiting
The purpose of this study is to compare how effective and how tolerable two different bowel preparation laxatives are for colonoscopy. The aim is to compare oral sulfate solution (OSS) to another laxative called 2L polyethylene glycol (PEG) solution to see which is more effective and more tolerable by individuals with IBD (Crohn's disease or Ulcerative colitis).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/06/2025
Locations: University of Manitoba, Winnipeg, Manitoba
Conditions: Crohn Disease, Ulcerative Colitis
Register for Updates
Fasting-mimicking Diet in Treatment of Depressive Symptoms in IBD
NCT05382897
Recruiting
Inflammatory bowel disease (IBD) is a chronic illness characterized by inflammation of the intestine. Many individuals with IBD suffer from depressive symptoms and anxiety which can lead to a decreased quality of life, poor treatment compliance, and higher morbidity and mortality. The object of this clinical trial is to investigate the effects of a fasting mimicking diet in IBD patients who are suffering with symptoms of depression. Participants will carry out 3 cycles of a 5-day period of a pla... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
08/30/2024
Locations: University of Alberta Hospital, Edmonton, Alberta +1 locations
Conditions: Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis
Register for Updates