There are currently 32 active clinical trials seeking participants for Ulcerative Colitis research studies. The states with the highest number of trials for Ulcerative Colitis participants are .
Longitudinal Study on Bacterial Production of LPC and LPA in Patients With Inflammatory Bowel Disease
NCT06548399
Recruiting
The purpose of this study is to investigate whether the gut bacteria in IBD patients cause ongoing abdominal pain, even when the disease is calm. Many inflammatory bowel disease (IBD) patients have this pain, regardless of whether their disease is active or not. This might be linked to an imbalance in gut bacteria. Certain IBD patients with persistent abdominal pain experience increased sensitivity in their gut due to bacteria producing LPC and LPA. Our goal is to explore the connection between... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
08/07/2024
Locations: McMaster University, Hamilton, Ontario
Conditions: Inflammatory Bowel Diseases, Crohn's Disease, Ulcerative Colitis
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ABTECT - Maintenance
NCT05535946
Recruiting
This is a multicenter, randomized, placebo-controlled study to evaluate the long-term efficacy and safety of ABX464 50mg and 25mg administered once daily (QD) as maintenance therapy in subjects with moderately to severely active ulcerative colitis who have inadequate response, no response, a loss of response, or an intolerance to either conventional therapies \[corticosteroids, immunosuppressant (i.e. azathioprine, 6-mercaptopurine, methotrexate)\] and/or advanced therapies \[biologics (TNF inhi... Read More
Gender:
ALL
Ages:
16 years and above
Trial Updated:
08/06/2024
Locations: University of Alabama -Birmingham, Birmingham, Alabama +553 locations
Conditions: Ulcerative Colitis
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Comparison Between Chromoendoscopy and Virtual Chromoendoscopy (NBI, I-scan, FICE) for Detection of Neoplasia in Long Standing Ulcerative Colitis
NCT01882205
Recruiting
The risk for colon cancer in patients with longstanding ulcerative colitis exceeding the rectum is increased and therefore patients should be enrolled in a surveillance program eight years after the diagnosis. Until today, official international guidelines for endoscopic screening in patients with ulcerative colitis advise to take 4 biopsies every 10 centimeters (with a minimum of 32) and of each suspected visible lesion. These guidelines are merely based on consensus during expert opinion meeti... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/09/2024
Locations: University Hospitals Leuven, Leuven, Not set +4 locations
Conditions: Ulcerative Colitis
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The Canadian Children Inflammatory Bowel Disease Network (CIDsCaNN)
NCT02308917
Recruiting
The CIDsCaNN Network is being established with the major goals of identifying why IBD develops so commonly in children and adolescents living in Canada, and of determining the best treatment strategies for different types of IBD. Focusing on a prospective, inception cohort of Canadian children of widely varied racial origins provides a unique opportunity to explore environmental risk factors early in life and close in time to disease onset, their influence on the host microbiome, and in the cont... Read More
Gender:
ALL
Ages:
Between 2 years and 17 years
Trial Updated:
03/18/2024
Locations: Alberta Children'S Hospital, Calgary, Alberta +11 locations
Conditions: Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn's
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A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)
NCT05442567
Recruiting
The study is an extension of two parent studies (MLN0002-3024 \[NCT04779307\] and MLN0002-3025 \[NCT04779320\]). Participants must have participated in one of the previous studies. The purpose of this study is to collect the long-term safety of vedolizumab in children with UC or CD.
Gender:
ALL
Ages:
2 years and above
Trial Updated:
03/05/2024
Locations: Phoenix Childrens Hospital -1919 E Thompson Rd, Phoenix, Arizona +67 locations
Conditions: Ulcerative Colitis, Crohn's Disease
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Postoperative Extended Venous Thromboprophylaxis in Inflammatory Bowel Disease
NCT03935451
Recruiting
Inflammatory bowel disease (IBD) is a relatively common disease that effects all age groups and carries significant morbidity and mortality. The initial treatment typically involves both short and long term medication, however when this is not enough to adequately control the disease, surgery is often required. The high morbidity and mortality rates are in part due to the increased rates of venous thromboembolism (VTE) such as deep vein thrombosis (DVT) or pulmonary embolism (PE) which have been... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/03/2024
Locations: St. Joseph's Healthcare, Hamilton, Ontario +1 locations
Conditions: IBD, Venous Thromboembolism, Crohn Disease, Ulcerative Colitis, Pulmonary Embolism, Colorectal Disorders
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Comparison of Functional Outcomes Between Transanal and Laparoscopic vs Open Ileal Pouch-Anal Anastomosis
NCT04722757
Recruiting
Background: Ulcerative colitis (UC) and inflammatory bowel unclassified (IBDu) are inflammatory bowel diseases (IBD) involving the colon and rectum. It is a chronic disease occurring in young people with a high burden on social and professional life. Although treated medically by immunomodulatory drugs, about 15 - 20% of UC patients will need an ileal pouch-anal anastomosis (IPAA). In primary cases, this procedure is usually performed laparoscopically (further called transabdominal IPAA or tabd-... Read More
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
09/01/2023
Locations: Mount Sinai Hospital, Toronto, Ontario
Conditions: Ulcerative Colitis, Inflammatory Bowel Diseases, Ileal Pouch
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An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Ulcerative Colitis
NCT04718818
Recruiting
The present study D5272C00001 (Legacy # 3151-201-008) seeks to evaluate the efficacy and safety of brazikumab versus placebo in patients with moderately to severely active UC and will include assessments of clinical responses as demonstrated by improvement of symptoms and of colonic mucosal appearance as observed on endoscopy.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
01/19/2021
Locations: Research Site, Tucson, Arizona +79 locations
Conditions: Ulcerative Colitis
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