Cisplatin Treatment Options in Canada

A collection of 326 research studies where Cisplatin is the interventional treatment. These studies are located in the Canada . Cisplatin is used for conditions such as Head and Neck Cancer, Lung Cancer and Non-small Cell Lung Cancer.

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A Study Evaluating the Safety, Activity, and Pharmacokinetics of Divarasib in Combination With Other Anti-Cancer Therapies in Participants With Previously Untreated Advanced or Metastatic Non-Small Cell Lung Cancer With a KRAS G12C Mutation

NCT05789082

Recruiting

The purpose of this study is to evaluate the safety, pharmacokinetics (PK), and activity of divarasib combined with other anti-cancer therapies in participants with previously untreated, advanced or metastatic non-small cell lung cancer (NSCLC).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/19/2025

Locations: City of Hope National Medical Center, Duarte, California +64 locations

City of Hope National Medical Center, Duarte, California

City of Hope - Seacliff, Huntington Beach, California

City of Hope at Irvine Lennar, Irvine, California

UCSD Moores Cancer Center, La Jolla, California

Yale Cancer Center, New Haven, Connecticut

NYU Langone Hospital - Long Island, Mineola, New York

NYU Cancer Center, New York, New York

Mount SInai Medical Center, New York, New York

MD Anderson Cancer Center, Houston, Texas

Oncology & Hematology Associates of Southwest Virginia, Inc, Blacksburg, Virginia

Virginia Oncology Associates, Norfolk, Virginia

Hospital Britanico, Buenos Aires, Not set

Clinica Adventista Belgrano, Ciudad Autonoma Buenos Aires, Not set

Centro Oncologico Riojano Integral (CORI), La Rioja, Not set

Concord Repatriation General Hospital, Concord, New South Wales

Peter MacCallum Cancer Centre, Melbourne, Victoria

Alfred Health, Melbourne, Victoria

Cliniques Universitaires St-Luc, Bruxelles, Not set

Jessa Zkh (Campus Virga Jesse), Hasselt, Not set

Clinique Ste-Elisabeth, Namur, Not set

AZ Delta (Campus Rumbeke), Roeselare, Not set

Hospital de Cancer de Barretos, Barretos, São Paulo

Instituto do Cancer do Estado de Sao Paulo - ICESP, Sao Paulo, São Paulo

Ottawa Hospital Regional Cancer Centre, Ottawa, Ontario

Princess Margaret Cancer Center, Toronto, Ontario

Jewish General Hospital, Montreal, Quebec

Hunan Cancer Hospital, Changsha CITY, Not set

Harbin Medical University Cancer Hospital, Harbin, Not set

Shanghai Pulmonary Hospital, Shanghai, Not set

Rambam Medical Center, Haifa, Not set

Rabin MC, Petach Tikva, Not set

Tel Aviv Sourasky Medical Ctr, Tel Aviv, Not set

Istituto Nazionale Tumori Fondazione G. Pascale, Napoli, Campania

Policlinico Universitario Agostino Gemelli IRCCS, Roma, Lazio

Irccs Istituto Nazionale Dei Tumori (Int), Milano, Lombardia

A.O. Universitaria S. Luigi Gonzaga, Orbassano, Piemonte

National Cancer Center Hospital East, Chiba, Not set

National Cancer Center Hospital, Tokyo, Not set

The Cancer Institute Hospital of JFCR, Tokyo, Not set

Wakayama Medical University Hospital, Wakayama, Not set

Pusan National University Hospital, Busan, Not set

Seoul National University Hospital, Seoul, Not set

Asan Medical Center, Seoul, Not set

Samsung Medical Center, Seoul, Not set

Korea University Guro Hospital, Seoul, Not set

NKI The Netherlands Cancer Institute, Amsterdam, Not set

UMC St Radboud, Nijmegen, Not set

Uniwersyteckie Centrum Kliniczne, Gda?sk, Not set

Krakowski Szpital Specjalistyczny im sw. Jana Paw?a II, Kraków, Not set

Warminsko-Mazurskie Centrum Chorób P?uc w Olsztynie, Olsztyn, Not set

ICO Badalona-H.U. Germans Trias i Pujol, Badalona, Barcelona

Vall d?Hebron Institute of Oncology (VHIO), Barcelona, Barcelona, Not set

Hospital General Universitario Gregorio Marañon, Madrid, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

Hospital Universitario Virgen del Rocio, Sevilla, Not set

Hospital Clinico Universitario de Valencia, Valencia, Not set

Sahlgrenska University Hospital, Göteborg, Not set

Universitätsspital Basel, Basel, Not set

Inselspital Bern, Bern, Not set

Taichung Veterans General Hospital, Taichung, Not set

National Cheng Kung University Hospital, Tainan, Not set

National Taiwan Uni Hospital, Taipei, Not set

Chang Gung Medical Foundation - Linkou, Taoyuan, Not set

Beatson West of Scotland Cancer Centre, Glasgow, Not set

Barts & London School of Med, London, Not set

Conditions: Non-Small Cell Lung Cancer

Learn More ›

Study BT8009-230 in Participants With Locally Advanced or Metastatic Urothelial Cancer (Duravelo-2)

NCT06225596

Recruiting

This is a global, multicenter, randomized, open-label study, with an adaptive design. The main objective of the study is to measure the efficacy and safety of BT8009 (zelenectide pevedotin) as monotherapy and in combination with pembrolizumab in participants with locally advanced or metastatic urothelial cancer (UC). The study includes a dose selection phase followed by an adaptive design continuation. The study is comprised of 2 cohorts. Cohort 1 will include participants who have not received... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/19/2025

Locations: University of Arkansas for Medical Sciences, Little Rock, Arkansas +169 locations

University of Arkansas for Medical Sciences, Little Rock, Arkansas

Virginia K. Crosson Cancer Center at St. Jude Medical Center, Fullerton, California

University of California - Irvine Medical Center, Orange, California

Adventist Health St. Helena, Saint Helena, California

University of California, San Francisco (UCSF), San Francisco, California

Rocky Mountain Cancer Center, Denver, Colorado

Yale University School of Medicine - Yale Cancer Center, New Haven, Connecticut

Medical Oncology Hematology Consultants, Newark, Delaware

Cancer Specialists of North Florida, Jacksonville, Florida

Mount Sinai Medical Center of Florida, Inc., Miami Beach, Florida

University of Miami - Sylvester Comprehensive Cancer Center, Miami, Florida

AP Medical Research, Miami, Florida

Moffitt, Tampa, Florida

Southern Illinois University (SIU) - Simmons Cancer Institute, Springfield, Illinois

Mission Cancer + Blood, Des Moines, Iowa

University of Kansas Cancer Center, Westwood, Kansas

UofL Health Brown Cancer Center, Louisville, Kentucky

Mary Bird Perkins Cancer Center, Baton Rouge, Louisiana

Princess Margaret Hospital, Grand Rapids, Michigan

Nebraska Cancer Specialists, Omaha, Nebraska

XCancer Omaha/Urology Cancer Center, Omaha, Nebraska

Astera Cancer Care, East Brunswick, New Jersey

Summit Health (New Jersey Urology), Voorhees, New Jersey

Montefiore Medical Center, Bronx, New York

Columbia University Irving Medical Center, New York, New York

University Hospitals Cleveland Medical Center, Cleveland, Ohio

Medical University of South Carolina (MUSC) - Hollings Cancer Center, Charleston, South Carolina

Carolina Urologic Research Center, Myrtle Beach, South Carolina

SCRI Oncology Partners, Nashville, Tennessee

The Center for Cancer and Blood Disorders, Fort Worth, Texas

MD Anderson Cancer Center, Houston, Texas

University of Texas Health Science Center at San Antonio, San Antonio, Texas

Centro de Diagnostico Urologico S.R.L., Buenos Aires, Not set

Hospital Britanico de Buenos Aires, Buenos Aires, Not set

Hospital Sirio Libanes de Buenos Aires, Buenos Aires, Not set

Instituto Alexander Fleming, Buenos Aires, Not set

Fundacion Medica Rio Negro y Neuquen, Cipolletti, Not set

Centro Medico Privado (CEMAIC), Córdoba, Not set

Fundación CORI para la investigación y Prevención del Cancer, La Rioja, Not set

Centro De Investigacion Pergamino S.A., Pergamino, Not set

Instituto de Oncologia de Rosario, Santa Fe, Not set

Clinica Viedma S.A., Viedma, Not set

Cancer Research SA, Adelaide, Not set

Mater Misericordiae Ltd, South Brisbane, Brisbane, Not set

Townsville Hospital and Health Service, Douglas, Not set

Barwon Health, Geelong, Not set

Calvary Mater Newcastle, Hunter, Not set

Sir Charles Gairdner Hospital, Nedlands, Not set

Blacktown Hospital, New South Wales, Not set

Prince of Wales Hospital, Randwick, Not set

Icon Cancer Centre, South Brisbane, Not set

Gold Coast University Hospital, Southport, Not set

Princess Alexandra Hospital, Woolloongabba, Not set

Urologie und Andrologie Ordensklinikum Linz GmbH Elisabethinen, Linz, Not set

Krankenhaus der Barmherzigen Brüder Wien, Wien, Not set

Medizinische Universitaet Wien, Wien, Not set

ASBL Grand Hôpital de Charleroi (GHdC), Site Notre Dame, Charleroi, Not set

General Hospital Maria Middelares, Gent, Not set

University Hospital Gent, Gent, Not set

Universitaire Ziekenhuizen Leuven, Leuven, Not set

Fundacao PIO XII - Hospital de Amor, Barretos, Not set

CEPEN - Centro de Pesquisa e Ensino em Oncologia de Santa Catarina, Florianópolis, Not set

Oncosite - Centro de Pesquisa Clinica Em Oncologia, Ijuí, Not set

Centro Gaucho Integrado de Oncologia, Hematologia, Ensino e Pesquisa, Porto Alegre, Not set

Hospital Sao Lucas - Pontificia Universidade Catolica do Rio Grande do Sul (PUCRS), Porto Alegre, Not set

Hospital Alemao Oswaldo Cruz, São Paulo, Not set

Hospital A.C. Camargo Cancer Center, São Paulo, Not set

British Columbia Cancer Agency- Centre for the Southern Interior, Kelowna, Not set

McGill University Health Center, Québec, Not set

Princess Margaret Hospital, Toronto, Not set

Cancer Care Manitoba, Winnipeg, Not set

Fundación Arturo López Pérez (FALP), Santiago, Not set

Centro de Investigacion Clinica Bradford Hill, Santiago, Not set

Oncocentro APYS, Viña Del Mar, Not set

Aalborg University Hospital, Aalborg, Not set

Service d'Oncologie Medicale - CHRU Besancon, Besançon, Not set

Institut Bergonie, Bordeaux Cedex, Not set

CHU Bordeaux - Hopital Saint-Andre, Bordeaux, Not set

Groupement de Cooperation Sanitaire (GCS) ELSAN - Clinique Victor Hugo, Le Mans, Not set

CHU de Limoges - Hopital Dupuytren 1, Limoges, Not set

Centre Leon Berard, Lyon, Not set

Institut Paoli-Calmettes, Marseille, Not set

ICM - Institut Regional du Cancer de Montpellier, Montpellier Cedex 5, Not set

Centre d'Oncologie de Gentilly, Nancy, Not set

Centre Antoine-Lacassagne, Nice, Not set

Institut Mutualiste Montsouris, Paris, Not set

AP-HP Hopital Europeen Georges Pompidou, Paris, Not set

HCL Centre Hospitalier Lyon Sud, Pierre-Benite Cedex, Not set

CHU Poitiers - Pole Regional de Cancerologie de Poitiers (PRC), Poitiers, Not set

Institut Gustave Roussy, Villejuif, Not set

LTD High Technology Hospital Medcenter, Batumi, Not set

The First University Clinic of Tbilisi State Medical University, Tbilisi, Not set

New Vision University Hospital, Tbilisi, Not set

Multiprofile Clinic Consilium Medulla LTD, Tbilisi, Not set

Universitaetsklinikum Carl Gustav Carus Dresden, Dresden, Not set

Universitaetsklinikum Essen, Essen, Not set

Krankenhaus Nordwest GmbH, Frankfurt, Not set

Universitaetsklinikum Frankfurt - Klinikum der Johann Wolfgang Goethe Universitaet, Frankfurt, Not set

Universitaetsklinikum Freiburg, Freiburg, Not set

Georg-August-Universitaet Goettingen Stiftung oeffentlichen Rechts Universitaetsmedizin Goettingen, Göttingen, Not set

Marien Hospital Herne - Universitaetsklinikum der Ruhr-Universitaet Bochum, Herne, Not set

Universitaetsmedizin Mannheim, Mannheim, Not set

Universitaetsklinikum Muenster, Münster, Not set

Studienpraxis Urologie, Nürtingen, Not set

Universitaetsklinikum Tuebingen, Tübingen, Not set

Orszagos Onkologiai Intezet, Budapest, Not set

Budapesti Uzsoki Utcai Korhaz, Budapest, Not set

Somogy Varmegyei Kaposi Mor Oktato Korhaz, Kaposvár, Not set

Bacs-Kiskun Varmegyei Oktatokorhaz, Kecskemét, Not set

Shamir Medical Center, Be'er Ya'aqov, Not set

Rambam Health Care Campus, Haifa, Not set

Hadassah Hebrew University Medical Center, Jerusalem, Not set

Meir Medical Center, Kfar Saba, Not set

Rabin Medical Center - Beilinson Hospital, Petach Tikva, Not set

Sourasky Medical Center, Tel Aviv, Not set

Centro Riferimento Oncologico - Aviano, Aviano, Not set

Ospedale Policlinico San Martino IRCCS, Genova, Not set

Istituto Europeo di Oncologia, Milano, Not set

Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", Napoli, Not set

Azienda Ospedaliera Santa Maria di Terni, Terni, Not set

Chungnam National University Hospital, Daejeon, Not set

National Cancer Center, Goyang, Not set

Chonnam National University Hwasun Hospital, Gwangju, Not set

Korea University Anam Hospital, Seoul, Not set

Seoul National University Hospital, Seoul, Not set

Asan Medical Center, Seoul, Not set

Samsung Medical Center, Seoul, Not set

Severance Hospital, Yonsei University Health System, Seoul, Not set

Copernicus PL Sp. z o.o., Wojewodzkie Centrum Onkologii, Gdańsk, Not set

Spitale Pomorskie Sp.z.o.o ODDZIAL ONKOLOGII KLINICZNEJ, Gdynia, Not set

SCM Sp. z o.o., Kraków, Not set

Mazowiecki Szpital Onkologiczny, Wieliszew, Not set

University Clinical Center of Serbia, Clinic of Urology, Belgrade, Not set

National University Hospital, Singapore, Not set

National Cancer Centre Singapore, Singapore, Not set

Hospital de la Santa Creu i Sant Pau, Barcelona, Not set

Hospital Clinic Barcelona, Barcelona, Not set

Institut Catala d'Oncologia - L'Hospitalet, Barcelona, Not set

Hospital Universitario Insular de Gran Canaria, Las Palmas De Gran Canaria, Not set

Hospital General Universitario Gregorio Maranon, Madrid, Not set

Clinica Universidad de Navarra - Madrid, Madrid, Not set

Hospital Fundacion Jimenez Diaz, Madrid, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

Hospital Universitario La Paz, Madrid, Not set

Clinica Universidad de Navarra - Pamplona, Pamplona, Not set

Hospital Universitario Donostia, San Sebastián, Not set

Hospital Universitario Marques de Valdecilla, Santander, Not set

Hospital Clinico Universitario de Santiago, Santiago De Compostela, Not set

Instituto Valenciano de Oncologia, Valencia, Not set

Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Not set

China Medical University Hospital, Taichung, Not set

National Cheng Kung University Hospital, Tainan, Not set

Chi Mei Medical Center, Tainan, Not set

National Taiwan University Hospital, Taipei, Not set

Linkou Chang Gung Memorial Hospital (CGMHLK), Taoyuan city, Not set

Liv Hospital Ankara, Ankara, Not set

Trakya University Medical Faculty, Edirne, Not set

Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Istanbul, Not set

Istinye Universitesi VM Medical Park Pendik Hastanesi, Istanbul, Not set

Medical Point Izmir Hospital, İzmir, Not set

Kocaeli University Faculty of Medicine, Kocaeli, Not set

Bristol Haematology and Oncology Centre, Bristol, Not set

Addenbrooke's Hospital, Cambridge, Not set

St. Bartholomew's Hospital, London, Not set

University College London Hospital, London, Not set

Royal Free London NHS Foundation Trust, London, Not set

Charing Cross Hospital, London, Not set

The Christie NHS Foundation Trust, Manchester, Not set

Derriford Hospital, Plymouth, Not set

The Royal Marsden Hospital, Sutton, Not set

Conditions: Metastatic Urothelial Cancer

Learn More ›

Study of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid Tumors

NCT03645928

Recruiting

A prospective, open-label, multi-cohort, non-randomized, multicenter Phase 2 study evaluating adoptive cell therapy (ACT) with TIL \[LN-144/LN-145 (lifileucel)\] in combination with immune checkpoint inhibitors or TIL \[LN-144/LN-145 (lifileucel) and LN-145-S1\] as a single agent therapy.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/18/2025

Locations: University of California, San Diego, La Jolla, California +44 locations

University of California, San Diego, La Jolla, California

University of Southern California, Los Angeles, California

University of California, Los Angeles, Los Angeles, California

University of Colorado, Denver, Colorado

Yale University, New Haven, Connecticut

Georgetown University Medical Center, Washington, District of Columbia

Mount Sinai Medical Center, Miami Beach, Florida

Orlando Health Cancer Institute, Orlando, Florida

Moffitt Cancer Center, Tampa, Florida

University of Louisville, Louisville, Kentucky

University of Maryland, Baltimore, Maryland

Massachusetts General Hospital, Boston, Massachusetts

Karmanos Cancer Institute, Detroit, Michigan

Henry Ford Health System, Detroit, Michigan

MD Anderson at Cooper, Camden, New Jersey

Morristown Medical Center, Morristown, New Jersey

Columbia University, New York, New York

Memorial Sloan Kettering Cancer Center, New York, New York

University of Cincinnati, Cincinnati, Ohio

Ohio State University, Columbus, Ohio

Avera Cancer Institute, Sioux Falls, South Dakota

Huntsman Cancer Hospital, Salt Lake City, Utah

Fred Hutchinson Cancer Research Center, Seattle, Washington

Medical College of Wisconsin, Milwaukee, Wisconsin

Princess Margaret Cancer Centre, Toronto, Ontario

Centre Léon Berard, Lyon, Not set

Klinikum rechts der Isar der Technischen Universität München, München, Bavaria

Universitätsklinikum Carl Gustav Carus, Dresden, Sachsen

Universitätsklinikum Schleswig-Holstein - Campus Lübeck, Lübeck, Schleswig-Holstein

Laiko General Hospital of Athens, Athens, Attiki

Attikon University General Hospital, Athens, Attiki

Hospital Universitario Marques de Valdecilla, Santander, Cantabria

University Hospital Vall d'Hebron, Barcelona, Not set

ICO l'Hospitalet - Hospital Duran i Reynals, Barcelona, Not set

Hospital General Universitario Gregorio Marañón, Madrid, Not set

Hospital Universitario Fundacion Jimenez Diaz, Madrid, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

Hospital Universitario HM Sanchinarro, Madrid, Not set

Hospital Regional Universitario de Malaga - Hospital General, Málaga, Not set

Universitätsspital Basel, Basel, Not set

Universitaetsspital Bern, Bern, Not set

Centre Hospitalier Universitaire Vaudois, Lausanne, Not set

Guy's Hospital, London, England

The Royal Marsden NHS Foundation Trust, London, England

Bristol Haematology and Oncology Centre, Bristol, Not set

Conditions: Metastatic Melanoma, Squamous Cell Carcinoma of the Head and Neck, Non-small Cell Lung Cancer

Learn More ›

Durvalumab+ Gemcitabine/Cisplatin (Neoadjuvant Treatment) and Durvalumab (Adjuvant Treatment) in Patients With MIBC

NCT03732677

Active Not Recruiting

A Global Study to Determine the Efficacy and Safety of Durvalumab in Combination with Gemcitabine+Cisplatin for Neoadjuvant Treatment and Durvalumab Alone for Adjuvant Treatment in Patients with Muscle-Invasive Bladder Cancer

Gender:

ALL

Ages:

Between 18 years and 130 years

Trial Updated:

06/17/2025

Locations: Research Site, Birmingham, Alabama +187 locations

Research Site, Birmingham, Alabama

Research Site, Los Angeles, California

Research Site, Palo Alto, California

Research Site, New Haven, Connecticut

Research Site, Chicago, Illinois

Research Site, Geneva, Illinois

Research Site, Iowa City, Iowa

Research Site, Westwood, Kansas

Research Site, Louisville, Kentucky

Research Site, New Orleans, Louisiana

Research Site, Towson, Maryland

Research Site, Ann Arbor, Michigan

Research Site, Detroit, Michigan

Research Site, New York, New York

Research Site, Rochester, New York

Research Site, Bethlehem, Pennsylvania

Research Site, Burlington, Vermont

Research Site, Milwaukee, Wisconsin

Research Site, Brisbane, Not set

Research Site, Elizabeth Vale, Not set

Research Site, Macquarie University, Not set

Research Site, Melbourne, Not set

Research Site, Murdoch, Not set

Research Site, South Brisbane, Not set

Research Site, Brugge, Not set

Research Site, Charleroi, Not set

Research Site, Kortrijk, Not set

Research Site, Leuven, Not set

Research Site, Liège, Not set

Research Site, Roeselare, Not set

Research Site, Barretos, Not set

Research Site, Porto Alegre, Not set

Research Site, Rio de Janeiro, Not set

Research Site, Santa Maria, Not set

Research Site, Sao Paulo, Not set

Research Site, São José do Rio Preto, Not set

Research Site, São Paulo, Not set

Research Site, Edmonton, Alberta

Research Site, Vancouver, British Columbia

Research Site, London, Ontario

Research Site, Ottawa, Ontario

Research Site, Toronto, Ontario

Research Site, Montreal, Quebec

Research Site, Sherbrooke, Quebec

Research Site, Antofagasta, Not set

Research Site, Puerto Montt, Not set

Research Site, Santiago, Not set

Research Site, Temuco, Not set

Research Site, Viña del Mar, Not set

Research Site, Brno, Not set

Research Site, Hradec Kralove, Not set

Research Site, Olomouc, Not set

Research Site, Praha 2, Not set

Research Site, Praha 8, Not set

Research Site, Praha, Not set

Research Site, Angers Cedex 01, Not set

Research Site, Dijon, Not set

Research Site, Grenoble Cedex 09, Not set

Research Site, Montpellier, Not set

Research Site, Nimes, Not set

Research Site, Pierre Benite, Not set

Research Site, Poitiers Cedex, Not set

Research Site, Rouen, Not set

Research Site, Bergisch Gladbach, Not set

Research Site, Bonn, Not set

Research Site, Erlangen, Not set

Research Site, Göttingen, Not set

Research Site, Herne, Not set

Research Site, Jena, Not set

Research Site, Köln, Not set

Research Site, Magdeburg, Not set

Research Site, Mannheim, Not set

Research Site, Münster, Not set

Research Site, Nürnberg, Not set

Research Site, Oldenburg, Not set

Research Site, Regensburg, Not set

Research Site, Ulm, Not set

Research Site, Würzburg, Not set

Research Site, Haifa, Not set

Research Site, Jerusalem, Not set

Research Site, Kfar Saba, Not set

Research Site, Petach-Tikva, Not set

Research Site, Ramat Gan, Not set

Research Site, Bari, Not set

Research Site, Bologna, Not set

Research Site, Firenze, Not set

Research Site, Milano, Not set

Research Site, Napoli, Not set

Research Site, Orbassano, Not set

Research Site, Pozzuoli, Not set

Research Site, Verona, Not set

Research Site, Bunkyo-ku, Not set

Research Site, Fukuoka-shi, Not set

Research Site, Fukuoka, Not set

Research Site, Hirosaki-shi, Not set

Research Site, Hiroshima-shi, Not set

Research Site, Kanazawa-shi, Not set

Research Site, Koto-ku, Not set

Research Site, Kumamoto-shi, Not set

Research Site, Miyazaki-city, Not set

Research Site, Nagasaki-shi, Not set

Research Site, Nagoya-shi, Not set

Research Site, Niigata-shi, Not set

Research Site, Osaka-shi, Not set

Research Site, Osakasayama-shi, Not set

Research Site, Sendai-shi, Not set

Research Site, Toyama-shi, Not set

Research Site, Tsukuba-shi, Not set

Research Site, Yokohama-shi, Not set

Research Site, Daegu, Not set

Research Site, Goyang-si, Not set

Research Site, Gyeonggi-do, Not set

Research Site, Incheon, Not set

Research Site, Seoul, Not set

Research Site, Amsterdam, Not set

Research Site, Breda, Not set

Research Site, Rotterdam, Not set

Research Site, Baguio City, Not set

Research Site, Cebu, Not set

Research Site, Davao City, Not set

Research Site, Makati, Not set

Research Site, Manila, Not set

Research Site, Quezon City, Not set

Research Site, Bialystok, Not set

Research Site, Gdańsk, Not set

Research Site, Grudziądz, Not set

Research Site, Koszalin, Not set

Research Site, Kraków, Not set

Research Site, Olsztyn, Not set

Research Site, Ostrołęka, Not set

Research Site, Poznan, Not set

Research Site, Warszawa, Not set

Research Site, Wroclaw, Not set

Research Site, Krasnoyarsk, Not set

Research Site, Moscow, Not set

Research Site, Nizhniy Novgorod, Not set

Research Site, Novosibirsk, Not set

Research Site, Samara, Not set

Research Site, St Petersburg, Not set

Research Site, St. Petersburg, Not set

Research Site, Ufa, Not set

Research Site, Vologda, Not set

Research Site, Badalona, Not set

Research Site, Barcelona, Not set

Research Site, Córdoba, Not set

Research Site, Las Palmas de Gran Canaria, Not set

Research Site, Madrid, Not set

Research Site, Santander, Not set

Research Site, Sevilla, Not set

Research Site, Kaohsiung, Not set

Research Site, Taichung, Not set

Research Site, Tainan, Not set

Research Site, Taipei City, Not set

Research Site, Taipei, Not set

Research Site, Taoyuan City, Not set

Research Site, Ankara, Not set

Research Site, Edirne, Not set

Research Site, Istanbul, Not set

Research Site, İstanbul, Not set

Research Site, Izmir, Not set

Research Site, Karsiyaka, Not set

Research Site, Edinburgh, Not set

Research Site, London, Not set

Research Site, Nottingham, Not set

Research Site, Sheffield, Not set

Research Site, Wirral, Not set

Research Site, Hanoi, Not set

Research Site, Ho Chi Minh, Not set

Research Site, Hochiminh, Not set

Conditions: Muscle Invasive Bladder Cancer

Learn More ›

Obinutuzumab in Combination With GDP Chemotherapy in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma

NCT02750670

Completed

This is a pilot study to determine the overall survival rate and toxicities of obinutuzumab given with GDP chemotherapy for relapsed or refractory CD20+ aggressive non-Hodgkin lymphoma. Patients who have CD20+ and progressed R-CHOP therapy will be enrolled into the study. About 30 patients are planned to be enrolled from Princess Margaret Cancer Centre. If the enrollment is very slow then additional site may be included. Patients will receive Obinutuzumab +GDP for 3 cycles intravenously. CT sca... Read More

Gender:

ALL

Ages:

Between 16 years and 70 years

Trial Updated:

06/17/2025

Locations: Princess Margaret Cancer Centre, Toronto, Ontario

Conditions: Lymphoma, Non-Hodgkin's

Learn More ›

A Study to Evaluate the Efficacy and Safety of Multiple Targeted Therapies as Treatments for Participants With Non-Small Cell Lung Cancer (NSCLC)

NCT03178552

Active Not Recruiting

This is a phase 2/3, global, multicenter, open-label, multi-cohort study designed to evaluate the safety and efficacy of targeted therapies or immunotherapy as single agents or in combination in participants with unresectable, advanced or metastatic NSCLC determined to harbor oncogenic somatic mutations or positive by tumor mutational burden (TMB) assay as identified by a blood-based next-generation sequencing (NGS) circulating tumor DNA (ctDNA) assay.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/11/2025

Locations: UC Davis, Sacramento, California +157 locations

UC Davis, Sacramento, California

Rocky Mountain Cancer Center, Denver, Colorado

SCRI Florida Cancer Specialists South, Fort Myers, Florida

Florida Cancer Specialist, North Region, Saint Petersburg, Florida

University of Kentucky, Lexington, Kentucky

Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada

Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire

Montefiore Medical Center, Bronx, New York

Weill Cornell Medical College-New York Presbyterian Hospital, New York, New York

Oregon HSU, Portland, Oregon

St. Luke's University Health network, Bethlehem, Pennsylvania

Sarah Cannon Research Institute / Tennessee Oncology, Chattanooga, Tennessee

Sarah Cannon Research Institute / Tennessee Oncology, Nashville, Tennessee

Fundación CENIT para la Investigación en Neurociencias, Buenos Aires, Not set

Hospital Italiano, Buenos Aires, Not set

Hospital Britanico de Buenos Aires, Ciudad Autonoma Buenos Aires, Not set

Royal North Shore Hospital, St Leonards, New South Wales

The Prince Charles Hospital, Chermside, Queensland

Ashford Cancer Center Research, Kurralta Park, South Australia

UZ Brussel, Brussel, Not set

UZ Leuven Gasthuisberg, Leuven, Not set

Oncosite - Centro de Pesquisa Clinica Em Oncologia Ltda, Ijui, Rio Grande Do Sul

Hospital Sao Lucas - PUCRS, Porto Alegre, Rio Grande Do Sul

Instituto do Cancer do Estado de Sao Paulo - ICESP, Sao Paulo, São Paulo

Cross Cancer Institute, Edmonton, Alberta

CancerCare Manitoba, Winnipeg, Manitoba

Royal Victoria Regional Health Centre, Barrie, Ontario

William Osler Health System Brampton Civic Hospital, Brampton, Ontario

London Health Sciences Centre · Victoria Hospital, London, Ontario

Lakeridge Health Center, Oshawa, Ontario

Sunnybrook Health Sciences Centre, Toronto, Ontario

Princess Margaret Cancer Center, Toronto, Ontario

Jewish General Hospital, Montreal, Quebec

IUCPQ (Hôpital Laval), Quebec City, Quebec

Saskatoon Cancer Centre, Saskatoon, Saskatchewan

Bradford Hill Centro de Investigaciones Clinicas, Recoleta, Not set

Beijing Cancer Hospital, Beijing, Not set

Jilin Cancer Hospital, Changchun, Not set

Hunan Cancer Hospital, Changsha City, Not set

The second Xiangya hospital of central south university, Changsha City, Not set

Sichuan Cancer Hospital, Chengdu City, Not set

West China Hospital - Sichuan University, Chengdu City, Not set

The First Affiliated Hospital of Guangzhou Medical University Pharmacy, Guangzhou, Not set

Zhejiang Cancer Hospital, Hangzhou City, Not set

Shandong Cancer Hospital, Jinan, Not set

The Second Affiliated Hospital to Nanchang University, Nanchang, Not set

Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing City, Not set

Fudan Unviversity Shanghai Cancer Center, Shanghai, Not set

First Affiliated Hospital of Medical College of Xi'an Jiaotong University, Xi'an, Not set

Centre Oscar Lambret, Lille, Not set

Centre Léon Bérard, Lyon, Not set

Hopital Caremeau, Nimes, Not set

Hôpital Européen Georges Pompidou, Paris, Not set

Hopital Tenon, Paris, Not set

CHU Poitiers, Poitiers, Not set

Hopital Pontchaillou, Rennes, Not set

CHU de Toulouse - Hôpital Larrey, Toulouse Cedex 9, Not set

Klinikum Chemnitz gGmbH, Chemnitz, Not set

Asklepios-Fachklinik Muenchen-Gauting, Gauting, Not set

Thoraxklinik Heidelberg gGmbH, Heidelberg, Not set

HSK Dr.-Horst-Schmidt-Kliniken Klinik für Innere Medizin III Onkologie Hämatologie und Palliativmed, Wiesbaden, Not set

Queen Mary Hospital, Hong Kong, Not set

Prince of Wales Hosp, Shatin, Not set

Soroka Medical Center, Beer Sheva, Not set

Rambam Health Care Campus, Haifa, Not set

Meir Medical Center, Kfar-Saba, Not set

Rabin MC, Petach Tikva, Not set

Chaim Sheba Medical Center, Ramat Gan, Not set

Sourasky / Ichilov Hospital; Dept. of Oncology, Tel Aviv, Not set

Istituto Nazionale per lo Studio e la Cura dei Tumori Fondazione G. Pascale, Napoli, Campania

IRST Istituto Scientifico Romagnolo Per Lo Studio E Cura Dei Tumori, Sede Meldola, Meldola, Emilia-Romagna

Irccs Centro Di Riferimento Oncologico (CRO), Aviano, Friuli-Venezia Giulia

Azienda Ospedaliera San Camillo Forlanini, Roma, Lazio

Asst Papa Giovanni XXIII, Bergamo, Lombardia

ASST di Cremona - Azienda Socio Sanitaria Territoriale di Cremona, Cremona, Lombardia

Irccs Istituto Europeo di Oncologia (IEO), Milano, Lombardia

Asst Di Monza, Monza, Lombardia

Azienda Sanitaria Ospedaliera S Luigi Gonzaga, Orbassano (TO), Piemonte

Tokyo Metropolitan Cancer and Infectious diseases Center Komagome Hospital, Bunkyo-ku, Not set

National Hospital Organization Kyushu Medical Center, Fukuoka, Not set

National Hospital Organization Kyushu Cancer Center, Fukuoka, Not set

Kyushu University Hospital, Fukuoka, Not set

Hiroshima University Hospital, Hiroshima, Not set

Kanazawa University Hospital, Ishikawa, Not set

Kanagawa Cancer Center, Kanagawa, Not set

University Hospital Kyoto Prefectural University of Medicine, Kyoto, Not set

Shikoku Cancer Center, Matsuyama-shi, Not set

Tohoku University Hospital, Miyagi, Not set

Sendai Kousei Hospital, Miyagi, Not set

Niigata Cancer Center Hospital, Niigata-shi, Not set

Niigata University Medical & Dental Hospital, Niigata, Not set

Kindai University Hospital, Osaka, Not set

Saga University Hospital, Saga, Not set

Shizuoka Cancer Center, Shizuoka, Not set

Juntendo University Hospital, Tokyo, Not set

The Cancer Institute Hospital of JFCR, Tokyo, Not set

Kyorin University Hospital, Tokyo, Not set

Fujita Health University Hospital, Toyoake-shi, Not set

Wakayama Medical University Hospital, Wakayama, Not set

National Hospital Organization Yamaguchi - Ube Medical Center, Yamaguchi, Not set

National Cancer Center, Gyeonggi-do, Not set

Chonnam National University Hwasun Hospital, Jeollanam-do, Not set

Seoul National University Hospital, Seoul, Not set

Asan Medical Center, Seoul, Not set

Yonsei University Health System/Severance Hospital, Seoul, Not set

Hospital Angeles Tijuana, Tijuana, BAJA California

Health Pharma Professional Research, Cdmx, Mexico CITY (federal District)

AVIX Investigación Clínica S.C, Monterrey, Nuevo LEON

Oncologico Potosino, San Luis Potosí, SAN LUIS Potosi

Auckland City Hospital, Auckland, Not set

Hemato Oncología de Panamá Especializada, Panama City, Not set

Hospital Nacional Edgardo Rebagliati Martins, Lima, Not set

Instituto Nacional de Enfermedades Neoplasicas, Lima, Not set

Instituto Peruano de Oncología y Radioterapia, Lima, Not set

Clinica Ricardo Palma, San Isidro, Not set

Warminsko-Mazurskie Centrum Chorób P?uc w Olsztynie, Olsztyn, Not set

Mazowieckie Centrum Leczenia Chorob Pluc I Gruzlicy, Otwock, Not set

Wielkopolskie Centrum Pulmonologii i Torakochirurgii w Poznaniu, Poznan, Not set

Narod.Inst.Onkol. im. M.Sklodowskiej - Curie-Panst.Inst.Bad, Warszawa, Not set

Moscow City Oncology Hospital #62, Moscovskaya Oblast, Moskovskaja Oblast

S-Pb clinical scientific practical center of specialized kinds of medical care (oncological), Saint-Petersburg, Sankt Petersburg

Clinical Oncology Dispensary, Omsk, Not set

Clinical Center of Serbia, Belgrade, Not set

University Hospital Medical Center Bezanijska kosa, Belgrade, Not set

Clinical Center Nis, NIS, Not set

National University Hospital, Singapore, Not set

National Cancer Centre, Singapore, Not set

Insititut Catala D'Oncologia, Hospitalet de Llobregat, Barcelona

Complejo Hospitalario Universitario de Santiago (CHUS), Santiago de Compostela, LA Coruna

Clinica Universitaria de Navarra, Pamplona, Navarra

Hospital General Univ. de Alicante, Alicante, Not set

Hospital Universitari Vall d'Hebron, Barcelona, Not set

Hospital Clínic i Provincial, Barcelona, Not set

ICO Badalona - Hospital Germans Trias i Pujol, Barcelona, Not set

Hospital General Universitario Gregorio Marañon, Madrid, Not set

Hospital Ramon y Cajal, Madrid, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

Centro Integral Oncologico Clara Campal, Madrid, Not set

Hospital Universitario Puerta de Hierro, Madrid, Not set

Hospital Quiron de Madrid, Madrid, Not set

Hospital Regional Universitario Carlos Haya, Malaga, Not set

Hospital Universitario Virgen del Rocio, Sevilla, Not set

Hospital Clínico Universitario de Valencia, Valencia, Not set

Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Not set

National Taiwan Uni Hospital, Taipei, Not set

Taipei Veterans General Hospital, Taipei, Not set

Chang Gung Medical Foundation - Linkou, Taoyuan, Not set

Chulalongkorn Hospital, Bangkok, Not set

Ramathibodi Hospital, Bangkok, Not set

Faculty of Med. Siriraj Hosp., Bangkok, Not set

Prince of Songkla University, Hat Yai, Not set

Baskent University Adana Dr. Turgut Noyan Practice and Research Hospital; Medical Oncology, Adana, Not set

Akdeniz University Medical Faculty; Medical Oncology Department, Antalya, Not set

Trakya University Medical Faculty Research And Practice Hospital Medical Oncology Department, Edirne, Not set

Medipol University Medical Faculty; Oncology Department, Istanbul, Not set

Marmara University Pendik Training and Research Hospital; Medikal Onkoloji, Istanbul, Not set

Medikal Park Izmir Hospital, Kar??yaka, Not set

Hacettepe Uni Medical Faculty Hospital; Oncology Dept, Sihhiye/Ankara, Not set

Conditions: Non-Small Cell Lung Cancer

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A Study of Toripalimab in Combination With Cisplatin and Gemcitabine in Participants With Recurrent Metastatic Nasopharyngeal Cancer

NCT06457503

Recruiting

This study aims to investigate toripalimab with chemotherapy in participants with nasopharyngeal cancer.

Gender:

ALL

Ages:

12 years and above

Trial Updated:

06/11/2025

Locations: University of Arkansas for Medical Sciences, Little Rock, Arkansas +9 locations

Conditions: Nasopharyngeal Cancer Recurrent

Learn More ›

A Study of Neoadjuvant/Adjuvant Durvalumab for the Treatment of Patients With Resectable Non-small Cell Lung Cancer

NCT03800134

Active Not Recruiting

This is a Phase III, randomized, double-blind, placebo-controlled, multi-center international study assessing the activity of durvalumab and chemotherapy administered prior to surgery compared with placebo and chemotherapy administered prior to surgery in terms of pathological complete response.

Gender:

ALL

Ages:

Between 18 years and 120 years

Trial Updated:

06/10/2025

Locations: Research Site, Phoenix, Arizona +230 locations

Research Site, Phoenix, Arizona

Research Site, Duarte, California

Research Site, Orange, California

Research Site, Aurora, Colorado

Research Site, Boca Raton, Florida

Research Site, Jacksonville, Florida

Research Site, Chicago, Illinois

Research Site, Wichita, Kansas

Research Site, Ashland, Kentucky

Research Site, Lexington, Kentucky

Research Site, Silver Spring, Maryland

Research Site, Towson, Maryland

Research Site, Duluth, Minnesota

Research Site, Minneapolis, Minnesota

Research Site, Morristown, New Jersey

Research Site, New York, New York

Research Site, Shirley, New York

Research Site, Durham, North Carolina

Research Site, Bend, Oregon

Research Site, Medford, Oregon

Research Site, Pittsburgh, Pennsylvania

Research Site, Charleston, South Carolina

Research Site, Austin, Texas

Research Site, Fort Worth, Texas

Research Site, Houston, Texas

Research Site, Fairfax, Virginia

Research Site, Kirkland, Washington

Research Site, Seattle, Washington

Research Site, Buenos Aires, Not set

Research Site, Caba, Not set

Research Site, La Plata, Not set

Research Site, Pergamino, Not set

Research Site, Rosario, Not set

Research Site, San Salvador de Jujuy, Not set

Research Site, Viedma, Not set

Research Site, Graz, Not set

Research Site, Innsbruck, Not set

Research Site, Rankweil, Not set

Research Site, Wien, Not set

Research Site, Gent, Not set

Research Site, Liège, Not set

Research Site, Mons, Not set

Research Site, Barretos, Not set

Research Site, Belo Horizonte, Not set

Research Site, Campinas, Not set

Research Site, Curitiba, Not set

Research Site, Florianópolis, Not set

Research Site, Natal, Not set

Research Site, Porto Alegre, Not set

Research Site, Santa Maria, Not set

Research Site, Sao Paulo, Not set

Research Site, São José do Rio Preto, Not set

Research Site, São Paulo, Not set

Research Site, Teresina, Not set

Research Site, Vitoria, Not set

Research Site, Plovdiv, Not set

Research Site, Sofia, Not set

Research Site, Edmonton, Alberta

Research Site, Kitchener, Ontario

Research Site, Levis, Quebec

Research Site, Montreal, Quebec

Research Site, Saskatoon, Saskatchewan

Research Site, Quebec, Not set

Research Site, Santiago, Not set

Research Site, Temuco, Not set

Research Site, Viña del Mar, Not set

Research Site, Beijing, Not set

Research Site, Changsha, Not set

Research Site, Changzhou, Not set

Research Site, Chengdu, Not set

Research Site, Guangzhou, Not set

Research Site, Guiyang, Not set

Research Site, Hangzhou, Not set

Research Site, Hefei, Not set

Research Site, Kunming, Not set

Research Site, Linhai, Not set

Research Site, Nanchang, Not set

Research Site, Ningbo, Not set

Research Site, Shanghai, Not set

Research Site, Shenyang, Not set

Research Site, Shenzhen, Not set

Research Site, Tianjin, Not set

Research Site, Urumqi, Not set

Research Site, Wuhan, Not set

Research Site, Xiamen, Not set

Research Site, Xintai, Not set

Research Site, Yangzhou, Not set

Research Site, Zhengzhou, Not set

Research Site, San José, Not set

Research Site, Avignon Cedex, Not set

Research Site, Lyon Cedex 08, Not set

Research Site, Nice, Not set

Research Site, Toulon Cedex 9, Not set

Research Site, Vantoux, Not set

Research Site, Bielefeld, Not set

Research Site, Frankfurt am Main, Not set

Research Site, Immenstadt, Not set

Research Site, Köln, Not set

Research Site, Budapest, Not set

Research Site, Gyöngyös - Mátraháza, Not set

Research Site, Győr, Not set

Research Site, Székesfehérvár, Not set

Research Site, Törökbálint, Not set

Research Site, Ahmedabad, Not set

Research Site, Gurgaon, Not set

Research Site, Kolkata, Not set

Research Site, Manipal, Not set

Research Site, Mumbai, Not set

Research Site, Mysuru, Not set

Research Site, Namakkal, Not set

Research Site, Nashik, Not set

Research Site, New Delhi, Not set

Research Site, Thane, Not set

Research Site, Vishakhapatnam, Not set

Research Site, Ancona, Not set

Research Site, Bari, Not set

Research Site, Bergamo, Not set

Research Site, Firenze, Not set

Research Site, Milano, Not set

Research Site, Monza, Not set

Research Site, Padova, Not set

Research Site, Roma, Not set

Research Site, Verona, Not set

Research Site, Habikino-shi, Not set

Research Site, Himeji-shi, Not set

Research Site, Hiroshima-shi, Not set

Research Site, Iwakuni-shi, Not set

Research Site, Kitaadachi-gun, Not set

Research Site, Kitakyushu-shi, Not set

Research Site, Kurashiki shi, Not set

Research Site, Nagoya-shi, Not set

Research Site, Niigata-shi, Not set

Research Site, Okayama-shi, Not set

Research Site, Osakasayama-shi, Not set

Research Site, Toyoake-shi, Not set

Research Site, Wakayama-shi, Not set

Research Site, Busan, Not set

Research Site, Cheongju-si, Not set

Research Site, Seongnam-si, Not set

Research Site, Seoul, Not set

Research Site, Suwon-si, Not set

Research Site, Suwon, Not set

Research Site, Aguascalientes, Not set

Research Site, Chihuahua, Not set

Research Site, Guadalajara, Not set

Research Site, Monterrey, Not set

Research Site, México, Not set

Research Site, Pachuca de Soto, Not set

Research Site, Arnhem, Not set

Research Site, Nijmegen, Not set

Research Site, Bellavista, Not set

Research Site, Lima, Not set

Research Site, Davao City, Not set

Research Site, Iloilo City, Not set

Research Site, Makati, Not set

Research Site, Quezon City, Not set

Research Site, Białystok, Not set

Research Site, Olsztyn, Not set

Research Site, Warszawa, Not set

Research Site, Suceava, Not set

Research Site, Kazan, Not set

Research Site, Krasnoyarsk, Not set

Research Site, Moscow, Not set

Research Site, Nizhniy Novgorod, Not set

Research Site, Obninsk, Not set

Research Site, Rostov-on-Don, Not set

Research Site, St. Petersburg, Not set

Research Site, Tomsk, Not set

Research Site, Yaroslavl, Not set

Research Site, Alicante, Not set

Research Site, Barcelona, Not set

Research Site, Madrid, Not set

Research Site, Málaga, Not set

Research Site, Oviedo, Not set

Research Site, Pamplona, Not set

Research Site, San Sebastian, Not set

Research Site, Santiago De Compostela (A Coruña), Not set

Research Site, Changhua, Not set

Research Site, Taichung City, Not set

Research Site, Taichung, Not set

Research Site, Tainan City, Not set

Research Site, Taipei City, Not set

Research Site, Taipei, Not set

Research Site, Bangkok, Not set

Research Site, Chiang Mai, Not set

Research Site, Chiang Rai, Not set

Research Site, Khon Kaen, Not set

Research Site, Lampang, Not set

Research Site, Hanoi, Not set

Research Site, Ho Chi Minh, Not set

Conditions: Non-Small Cell Lung Cancer

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Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial Cancer

NCT04491942

Active Not Recruiting

This phase I trial identifies the best dose, possible benefits and/or side effects of BAY 1895344 in combination with chemotherapy in treating patients with solid tumors or urothelial cancer that has spread to other places in the body (advanced). BAY 1895344 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Cisplatin and gemcitabine are chemotherapy drugs that stop the growth of tumor cells by killing the cells. Combining BAY 1895344 with chemotherapy tre... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/07/2025

Locations: University of California Davis Comprehensive Cancer Center, Sacramento, California +7 locations

Conditions: Advanced Bile Duct Carcinoma, Advanced Breast Carcinoma, Advanced Cervical Carcinoma, Advanced Endometrial Carcinoma, Advanced Esophageal Carcinoma, Advanced Gastric Carcinoma, Advanced Head and Neck Carcinoma, Advanced Lung Non-Small Cell Carcinoma, Advanced Lung Small Cell Carcinoma, Advanced Malignant Solid Neoplasm, Advanced Ovarian Carcinoma, Advanced Penile Carcinoma, Advanced Pleural Malignant Mesothelioma, Advanced Urothelial Carcinoma, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8, Clinical Stage III Gastric Cancer AJCC v8, Clinical Stage IV Gastric Cancer AJCC v8, Stage III Cervical Cancer AJCC v8, Stage III Distal Bile Duct Cancer AJCC v8, Stage III Intrahepatic Bile Duct Cancer AJCC v8, Stage III Lung Cancer AJCC v8, Stage III Ovarian Cancer AJCC v8, Stage III Penile Cancer AJCC v8, Stage III Pleural Malignant Mesothelioma AJCC v8, Stage IV Cervical Cancer AJCC v8, Stage IV Distal Bile Duct Cancer AJCC v8, Stage IV Intrahepatic Bile Duct Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Stage IV Ovarian Cancer AJCC v8, Stage IV Penile Cancer AJCC v8, Stage IV Pleural Malignant Mesothelioma AJCC v8, Triple-Negative Breast Carcinoma, Unresectable Urothelial Carcinoma

Learn More ›

Phase III Open Label First Line Therapy Study of MEDI 4736 (Durvalumab) With or Without Tremelimumab Versus SOC in Non Small-Cell Lung Cancer (NSCLC)

NCT02453282

Active Not Recruiting

This is a randomized, open-label, multi-center, global, Phase III study to determine the efficacy and safety of MEDI4736 + tremelimumab combination therapy and MEDI4736 monotherapy versus platinum-based SoC chemotherapy in the first-line treatment of patients with epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK) wild-type locally advanced or metastatic NSCLC

Gender:

ALL

Ages:

Between 18 years and 130 years

Trial Updated:

06/06/2025

Locations: Research Site, Scottsdale, Arizona +198 locations

Research Site, Scottsdale, Arizona

Research Site, Tucson, Arizona

Research Site, Yuma, Arizona

Research Site, Bakersfield, California

Research Site, Fullerton, California

Research Site, La Jolla, California

Research Site, Los Angeles, California

Research Site, Redondo Beach, California

Research Site, Sacramento, California

Research Site, San Luis Obispo, California

Research Site, Santa Maria, California

Research Site, West Hollywood, California

Research Site, New Haven, Connecticut

Research Site, Jacksonville, Florida

Research Site, Pembroke Pines, Florida

Research Site, Tampa, Florida

Research Site, Athens, Georgia

Research Site, Honolulu, Hawaii

Research Site, Baltimore, Maryland

Research Site, Minneapolis, Minnesota

Research Site, Saint Louis, Missouri

Research Site, Omaha, Nebraska

Research Site, Summit, New Jersey

Research Site, Mineola, New York

Research Site, New York, New York

Research Site, Charlotte, North Carolina

Research Site, Cleveland, Ohio

Research Site, North Charleston, South Carolina

Research Site, Nashville, Tennessee

Research Site, Richmond, Virginia

Research Site, Madison, Wisconsin

Research Site, Box Hill, Not set

Research Site, Gosford, Not set

Research Site, Kogarah, Not set

Research Site, Melbourne, Not set

Research Site, Port Macquarie, Not set

Research Site, Southport, Not set

Research Site, St Leonards, Not set

Research Site, Brussels, Not set

Research Site, Charleroi, Not set

Research Site, Duffel, Not set

Research Site, Leuven, Not set

Research Site, Liège, Not set

Research Site, Kingston, Ontario

Research Site, Newmarket, Ontario

Research Site, Oshawa, Ontario

Research Site, Sault Ste. Marie, Ontario

Research Site, St. Catharines, Ontario

Research Site, Sudbury, Ontario

Research Site, Toronto, Ontario

Research Site, Regina, Saskatchewan

Research Site, Saskatoon, Saskatchewan

Research Site, Bordeaux Cedex, Not set

Research Site, Brest Cedex, Not set

Research Site, Creteil, Not set

Research Site, Lille, Not set

Research Site, Lyon Cedex 08, Not set

Research Site, Marseille cedex, Not set

Research Site, Aachen, Not set

Research Site, Bad Berka, Not set

Research Site, Berlin, Not set

Research Site, Freiburg, Not set

Research Site, Gauting, Not set

Research Site, Hamburg, Not set

Research Site, Heidelberg, Not set

Research Site, Hemer, Not set

Research Site, Homburg/Saar, Not set

Research Site, Immenhausen, Not set

Research Site, Lubeck, Not set

Research Site, Löwenstein, Not set

Research Site, Mainz, Not set

Research Site, Münster, Not set

Research Site, Oldenburg, Not set

Research Site, Ulm, Not set

Research Site, Velbert, Not set

Research Site, Würzburg, Not set

Research Site, Budapest, Not set

Research Site, Deszk, Not set

Research Site, Edelény, Not set

Research Site, Kaposvár, Not set

Research Site, Kecskemét, Not set

Research Site, Miskolc, Not set

Research Site, Nyíregyháza, Not set

Research Site, Pécs, Not set

Research Site, Székesfehérvár, Not set

Research Site, Genova, Not set

Research Site, Meldola, Not set

Research Site, Milano, Not set

Research Site, San Giovanni Rotondo, Not set

Research Site, Siena, Not set

Research Site, Fukushima-shi, Not set

Research Site, Himeji-shi, Not set

Research Site, Hirakata-shi, Not set

Research Site, Hirosaki-shi, Not set

Research Site, Iizuka-shi, Not set

Research Site, Iwakuni-shi, Not set

Research Site, Izumi-shi, Not set

Research Site, Kanazawa, Not set

Research Site, Kishiwada-shi, Not set

Research Site, Kobe-shi, Not set

Research Site, Koga-shi, Not set

Research Site, Kyoto-shi, Not set

Research Site, Mitaka-shi, Not set

Research Site, Nagaoka-shi, Not set

Research Site, Nagoya-shi, Not set

Research Site, Okayama-shi, Not set

Research Site, Osaka-shi, Not set

Research Site, Osakasayama, Not set

Research Site, Saga-shi, Not set

Research Site, Saitama-shi, Not set

Research Site, Sakai-shi, Not set

Research Site, Sendai-shi, Not set

Research Site, Shinjuku-ku, Not set

Research Site, Tokushima-shi, Not set

Research Site, Ube-shi, Not set

Research Site, Yokohama-shi, Not set

Research Site, Yokosuka-shi, Not set

Research Site, Busan, Not set

Research Site, Changwon-si, Not set

Research Site, Cheongju-si, Not set

Research Site, Daegu, Not set

Research Site, Daejeon, Not set

Research Site, Goyang-si, Not set

Research Site, Incheon, Not set

Research Site, Jinju-si, Not set

Research Site, Seongnam-si, Not set

Research Site, Seongnam-Si, Not set

Research Site, Seoul, Not set

Research Site, Suwon-si, Not set

Research Site, Ulsan, Not set

Research Site, Amsterdam, Not set

Research Site, Arnhem, Not set

Research Site, Breda, Not set

Research Site, Den Bosch, Not set

Research Site, Groningen, Not set

Research Site, Maastricht, Not set

Research Site, Rotterdam, Not set

Research Site, Moscow, Not set

Research Site, Obninsk, Not set

Research Site, Omsk, Not set

Research Site, Saint Petersburg, Not set

Research Site, Saint-Petersburg, Not set

Research Site, St. Petersburg, Not set

Research Site, A Coruña, Not set

Research Site, Alicante, Not set

Research Site, Barcelona, Not set

Research Site, Gerona, Not set

Research Site, Jaén, Not set

Research Site, León, Not set

Research Site, Madrid, Not set

Research Site, Majadahonda, Not set

Research Site, Málaga, Not set

Research Site, Sevilla, Not set

Research Site, Valencia, Not set

Research Site, Bellinzona, Not set

Research Site, Lausanne, Not set

Research Site, Kaohsiung, Not set

Research Site, Taichung, Not set

Research Site, Tainan City, Not set

Research Site, Taipei, Not set

Research Site, Tao-Yuan, Not set

Research Site, Bangkok, Not set

Research Site, Chiang Mai, Not set

Research Site, Hat Yai, Not set

Research Site, Khon Kaen, Not set

Research Site, Hanoi City, Not set

Research Site, Hanoi, Not set

Research Site, Ho Chi Minh city, Not set

Research Site, Ho Chi Minh, Not set

Conditions: Non-Small-Cell Lung Carcinoma NSCLC

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Study of Pembrolizumab (MK-3475) in Combination With Adjuvant Chemotherapy With or Without Radiotherapy in Participants With Newly Diagnosed Endometrial Cancer After Surgery With Curative Intent (MK-3475-B21 / KEYNOTE-B21 / ENGOT-en11 / GOG-3053)

NCT04634877

Active Not Recruiting

The purpose of this study is to compare pembrolizumab + adjuvant chemotherapy with placebo + adjuvant chemotherapy, with or without radiotherapy, with respect to disease-free survival (DFS) as assessed radiographically by the investigator or by histopathologic confirmation of suspected disease recurrence, and with respect to overall survival (OS). The primary hypotheses are that pembrolizumab + adjuvant chemotherapy is superior to placebo + adjuvant chemotherapy, with or without radiotherapy, wi... Read More

Gender:

FEMALE

Ages:

18 years and above

Trial Updated:

06/05/2025

Locations: University of Alabama - Birmingham ( Site 3061), Birmingham, Alabama +230 locations

University of Alabama - Birmingham ( Site 3061), Birmingham, Alabama

University of South Alabama, Mitchell Cancer Institute ( Site 3058), Mobile, Alabama

HonorHealth Research Institute - Biltmore ( Site 3043), Phoenix, Arizona

Arizona Oncology Associates PC- HOPE ( Site 3049), Tucson, Arizona

UCSD Moores Cancer Center ( Site 3053), La Jolla, California

University Of Colorado ( Site 3051), Aurora, Colorado

Smilow Cancer Hospital at Yale New Haven ( Site 3070), New Haven, Connecticut

Mount Sinai Cancer Center ( Site 3081), Miami Beach, Florida

Northside Hospital ( Site 3036), Atlanta, Georgia

Northwestern Memorial Hospital ( Site 3044), Chicago, Illinois

Parkview Cancer Institute ( Site 3067), Fort Wayne, Indiana

Indiana University Melvin and Bren Simon Cancer Center ( Site 3071), Indianapolis, Indiana

University of Iowa Hospital and Clinics ( Site 3046), Iowa City, Iowa

Norton Cancer Institute - St. Matthews ( Site 3056), Louisville, Kentucky

WK Physicians Network/Gynecologic Oncology Associates ( Site 3047), Shreveport, Louisiana

University of Massachusetts Medical School ( Site 3037), Worcester, Massachusetts

Montefiore Medical Center ( Site 3065), Bronx, New York

Perlmutter Cancer Center at NYU Langone Hospital - Long Island ( Site 3076), Mineola, New York

Laura and Isaac Perlmutter Cancer Center at NYU Langone Health ( Site 3042), New York, New York

Duke Cancer Center ( Site 3072), Durham, North Carolina

Sanford Fargo Medical Center-Roger Maris Cancer Center ( Site 3080), Fargo, North Dakota

The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive C, Columbus, Ohio

Legacy Good Samaritan Medical Center ( Site 3033), Portland, Oregon

Sidney Kimmel Cancer Center - Jefferson Health ( Site 3078), Philadelphia, Pennsylvania

AHN West Penn Hospital ( Site 3060), Pittsburgh, Pennsylvania

Abington Hospital - Asplundh Cancer Center ( Site 3073), Willow Grove, Pennsylvania

Sanford Gynecology Oncology ( Site 3045), Sioux Falls, South Dakota

UT Southwestern Medical Center ( Site 3063), Dallas, Texas

VCU Massey Cancer Center ( Site 3068), Richmond, Virginia

Centro de Oncología e Investigación de Buenos Aires ( Site 1005), Berazategui, Buenos Aires

IDIM Instituto de Diagnostico e Investigaciones Metabolicas ( Site 1006), Caba, Buenos Aires

Instituto de Investigaciones Clinicas Mar del Plata ( Site 1003), Mar del Plata, Buenos Aires

Hospital Britanico de Buenos Aires ( Site 1002), Buenos Aires, Caba

Instituto de Oncologia de Rosario ( Site 1004), Rosario, Santa Fe

IDIM - Instituto de Diagnóstico e Investigaciones Metabólicas ( Site 1010), Buenos Aires, Not set

Hospital Aleman ( Site 1001), Buenos Aires, Not set

CEMIC ( Site 1009), Buenos Aires, Not set

Centro Oncologico Riojano Integral ( Site 1007), La Rioja, Not set

Medizinische Universitat Graz ( Site 2004), Graz, Steiermark

Medizinische Universitaet Innsbruck ( Site 2001), Innsbruck, Tirol

Saint-Luc UCL ( Site 2042), Bruxelles, Bruxelles-Capitale, Region De

C.I.U. Hopital Ambroise Pare ( Site 2039), Mons, Hainaut

CHR Verviers ( Site 2035), Verviers, Liege

OLV Ziekenhuis ( Site 2038), Aalst, Oost-Vlaanderen

AZ Maria Middelares Gent ( Site 2032), Gent, Oost-Vlaanderen

Universitair Ziekenhuis Gent ( Site 2037), Gent, Oost-Vlaanderen

AZ Nikolaas ( Site 2031), Sint-Niklaas, Oost-Vlaanderen

UZ Leuven ( Site 2040), Leuven, Vlaams-Brabant

AZ Groeninge ( Site 2036), Kortrijk, West-Vlaanderen

CHC - Groupe Sante ( Site 2041), Liege, Not set

CHU Liege Sart-Tilman ( Site 2044), Liege, Not set

Tom Baker Cancer Centre ( Site 3007), Calgary, Alberta

Kingston Health Sciences Centre ( Site 3003), Kingston, Ontario

Centre Hospitalier de l Universite de Montreal - CHUM ( Site 3006), Montreal, Quebec

McGill University Health Centre ( Site 3005), Montreal, Quebec

Centre intégré de cancérologie du CHU de Québec Université Laval, Hôpital de l'Enfant-Jésus ( Site 3, Quebec City, Quebec

Centro Investigación del Cáncer James Lind ( Site 1061), Temuco, Araucania

Fundacion Arturo Lopez Perez FALP ( Site 1062), Santiago, Region M. De Santiago

Centro de Cancer Nuestra Senora de la Esperanza ( Site 1063), Santiago, Region M. De Santiago

Bradfordhill-Clinical Area ( Site 1070), Santiago, Region M. De Santiago

Oncocentro ( Site 1065), Vina del Mar, Valparaiso

Anhui Provincial Hospital-Obstetrics and Gynecology ( Site 4034), Hefei, Anhui

Beijing Cancer Hospital ( Site 4048), Beijing, Beijing

Peking Union Medical College Hospital ( Site 4036), Beijing, Beijing

Chongqing Cancer Hospital ( Site 4040), Chongqing, Chongqing

The First Affiliated Hospital of Xiamen University ( Site 4060), Xiamen, Fujian

The First Affiliated Hospital ( Site 4043), Guangzhou, Guangdong

Guangxi Medical University Affiliated Tumor Hospital ( Site 4049), Nanning, Guangxi

Harbin Medical University Cancer Hospital ( Site 4033), Harbin, Heilongjiang

Hubei Cancer Hospital ( Site 4059), Wuhan, Hubei

Xiangya Hospital Central-South University ( Site 4035), Changsha, Hunan

Hunan Cancer Hospital ( Site 4050), Changsha, Hunan

Nanjing Drum Tower Hospital ( Site 4037), Nanjing, Jiangsu

Jiangxi Maternal and Child Health Hospital ( Site 4051), Nanchang, Jiangxi

The First Bethune Hospital of Jilin University ( Site 4057), Changchun, Jilin

The First Affiliated Hospital of Xi an Jiaotong University ( Site 4045), XI An, Shaanxi

Obstetrics and Gynecology Hosp. Fudan University ( Site 4041), Shanghai, Shanghai

Shanghai Renji Hospital Affiliated to Jiao Tong University ( Site 4053), Shanghai, Shanghai

Shanghai First Maternity and Infant Hospital-Gynecology department ( Site 4001), Shanghai, Shanghai

Sichuan Cancer Hospital ( Site 4039), Chengdu, Sichuan

Tianjin Medical University Cancer Institute & Hospital ( Site 4054), Tianjin, Tianjin

Yunnan Province Cancer Hospital-Gynecology Department ( Site 4055), Kunming, Yunnan

The First Affiliated Hospital, Zhejiang University-Gynecology ( Site 4002), Hangzhou, Zhejiang

Women s Hospital School of Medicine Zhejiang University ( Site 4032), Hangzhou, Zhejiang

The First Affiliated Hospital of Wenzhou Medical University ( Site 4056), Wenzhou, Zhejiang

Clínica Vida Fundación - Sede Poblado ( Site 1096), Medellin, Antioquia

Instituto Nacional de Cancerología E.S.E ( Site 1094), Bogota, Distrito Capital De Bogota

Instituto Cancerologico de Narino Ltda ( Site 1092), San Juan De Pasto, Narino

Fundacion Valle del Lili ( Site 1093), Cali, Valle Del Cauca

Fakultní nemocnice Brno Bohunice-Gynekologicko-porodnicka klinika ( Site 2394), Brno, Brno-mesto

Fakultni nemocnice Kralovske Vinohrady ( Site 2393), Praha, Praha 10

Vseobecna fakultni nemocnice v Praze ( Site 2391), Praha, Praha 2

Fakultni nemocnice Olomouc ( Site 2392), Olomouc, Not set

Rigshospitalet University Hospital ( Site 2515), Copehagen, Hovedstaden

Herlev Hospital ( Site 2514), Herlev, Hovedstaden

Aalborg Universitetshospital ( Site 2511), Aalborg, Nordjylland

Roskilde Sygehus ( Site 2513), Roskilde, Sjaelland

Odense Universitetshospital ( Site 2512), Odense, Syddanmark

Tampere University Hospital ( Site 2541), Tampere, Pirkanmaa

Kuopio University Hospital ( Site 2543), Kuopio, Pohjois-Savo

Turku University Hospital ( Site 2542), Turku, Varsinais-Suomi

Institut De Cancerologie De Lorraine ( Site 2072), Vandoeuvre les Nancy, Ain

Centre Antoine Lacassagne ( Site 2073), Nice, Alpes-Maritimes

Centre Francois Baclesse ( Site 2062), Caen, Calvados

Hôpital Privé Des Côtes d'Armor ( Site 2063), Plérin, Cotes-d Armor

CHU Besancon - Hopital Jean Minjoz ( Site 2068), Besancon, Doubs

Institut Bergonie ( Site 2067), Bordeaux, Gironde

Institut Universitaire du Cancer Toulouse - Oncopole ( Site 2065), Toulouse, Haute-Garonne

Institut Regional du Cancer de Montpellier - ICM ( Site 2069), Montpellier, Herault

Hopital Cochin ( Site 2070), Paris, Ile-de-France

Gustave Roussy ( Site 2071), Villejuif, Ile-de-France

Hopital prive du Confluent ( Site 2061), Nantes, Loire-Atlantique

Centre Hospitalier Lyon Sud ( Site 2064), Pierre Benite, Rhone

SLK-Kliniken Heilbronn GmbH ( Site 2116), Heilbronn, Baden-Wurttemberg

Klinikum Ludwigsburg ( Site 2111), Ludwigsburg, Baden-Wurttemberg

Universitaetsklinikum Tuebingen ( Site 2113), Tübingen, Baden-Wurttemberg

Medizinische Hochschule Hannover-Department of Obstetrics and Gynecology ( Site 2109), Hannover, Niedersachsen

Universitätsklinikum Bonn-Gynaecological oncology ( Site 2103), Bonn, Nordrhein-Westfalen

Kliniken Essen-Mitte, Evangelische Huyssens-Stiftung ( Site 2105), Essen, Nordrhein-Westfalen

Universitaetsklinikum Carl Gustav Carus Dresden-Klinik und Poliklinik für Frauenheilkunde und Gebur, Dresden, Sachsen

Universitätsklinikum Schleswig-Holstein ( Site 2101), Lübeck, Schleswig-Holstein

General Hospital of Patras. St Andrews ( Site 2421), Patras, Achaia

Geniko Panepistimako Nosokomeio ARETEIO ( Site 2423), Athens, Attiki

Perifereiako Geniko Nosokomeio ALEXANDRA ( Site 2425), Athens, Attiki

Athens University Hospital ATTIKON ( Site 2424), Chaidari, Attiki

Hospital Hygeia ( Site 2426), Marousi, Attiki

Euromedica General Clinic of Thessaloniki ( Site 2422), Thessaloniki, Not set

Rambam Medical Center ( Site 2307), Haifa, Not set

Edith Wolfson Medical Center ( Site 2306), Holon, Not set

Hadassah Medical Center. Ein Kerem ( Site 2303), Jerusalem, Not set

Rabin Medical Center ( Site 2305), Petah Tikva, Not set

Chaim Sheba Medical Center ( Site 2301), Ramat Gan, Not set

Istittuto Nazionale dei Tumori Regina Elena IRCCS - IFO ( Site 2121), Roma, Abruzzo

Fondazione Policlinico Universitario Agostino Gemelli ( Site 2124), Roma, Lazio

Istituto di Candiolo - IRCCS ( Site 2125), Candiolo, Piemonte

Azienda Ospedaliera Spedali Civili di Brescia ( Site 2135), Brescia, Not set

IRCCS Ospedale San Raffaele ( Site 2130), Milano, Not set

Fondazione IRCCS Istituto Nazionale dei Tumori di Milano ( Site 2122), Milano, Not set

Istituto Europeo di Oncologia IRCCS-Divisione di Ginecologia Oncologica ( Site 2132), Milano, Not set

Azienda Ospedaliera Universitaria Federico II ( Site 2123), Napoli, Not set

Istituto Nazionale Tumori IRCCS Fondazione Pascale ( Site 2127), Napoli, Not set

Istituto Oncologico Veneto IRCCS-Oncologia 2 ( Site 2134), Padova, Not set

Aichi Cancer Center Hospital ( Site 4190), Nagoya, Aichi

National Cancer Center Hospital East ( Site 4197), Kashiwa, Chiba

National Hospital Organization Shikoku Cancer Center ( Site 4181), Matsuyama, Ehime

Ehime University Hospital ( Site 4187), Toon, Ehime

Kurume University Hospital ( Site 4186), Kurume, Fukuoka

Gunma Prefectural Cancer Center ( Site 4183), Ota, Gunma

Hokkaido University Hospital ( Site 4194), Sapporo, Hokkaido

Hyogo Cancer Center ( Site 4195), Akashi, Hyogo

Iwate Medical University Hospital ( Site 4189), Shiwa-gun, Iwate

University of the Ryukyus Hospital ( Site 4184), Nakagami-gun, Okinawa

Saitama Medical University International Medical Center ( Site 4182), Hidaka, Saitama

Shizuoka Cancer Center Hospital and Research Institute ( Site 4192), Sunto-gun, Shizuoka

National Hospital Organization Kyushu Cancer Center ( Site 4193), Fukuoka, Not set

Niigata Cancer Center Hospital ( Site 4185), Niigata, Not set

Osaka International Cancer Institute ( Site 4188), Osaka, Not set

The Cancer Institute Hospital of JFCR ( Site 4196), Tokyo, Not set

Keio University Hospital ( Site 4191), Tokyo, Not set

National Cancer Center ( Site 4065), Goyang-si, Kyonggi-do

Seoul National University Bundang Hospital ( Site 4063), Seongnam-si, Kyonggi-do

Severance Hospital Yonsei University Health System ( Site 4062), Seoul, Not set

Asan Medical Center ( Site 4061), Seoul, Not set

Samsung Medical Center ( Site 4064), Seoul, Not set

Investigacion Onco Farmaceutica S de RL de CV ( Site 1127), La Paz, Baja California Sur

Hospital San Lucas Cardiologica del Sureste ( Site 1122), Tuxtla Gutierrez, Chiapas

Instituto Nacional de Cancerologia ( Site 1124), Cdmx, Distrito Federal

Christus Muguerza Clinica Vidriera ( Site 1125), Monterrey, Nuevo Leon

I Can Oncology Center SA de CV ( Site 1126), Monterrey, Nuevo Leon

Hospital Angeles Roma ( Site 1123), Ciudad de Mexico, Not set

Centro Oncologico Internacional. SEDNA ( Site 1121), Mexico City, Not set

University Hospital of North Norway ( Site 2153), Tromso, Troms

Soerlandet sykehus HF Kristiansand ( Site 2152), Kristiansand, Vest-Agder

Oslo Universitetssykehus Radiumhospitalet ( Site 2151), Oslo, Not set

Mazowiecki Szpital Wojewódzki w Siedlcach-Siedleckie Centrum Onkologii ( Site 2487), Siedlce, Mazowieckie

Szpital Kliniczny im Ks Anny Mazowieckiej ( Site 2481), Warszawa, Mazowieckie

Bialostockie Centrum Onkologii ( Site 2483), Bialystok, Podlaskie

Narodowy Instytut Onkologii - Oddzial w Gliwicach ( Site 2482), Gliwice, Slaskie

Swietokrzyskie Centrum Onkologii SPZOZ ( Site 2485), Kielce, Swietokrzyskie

SPZOZ MSWIA z Warminsko-Mazurskim Centrum Onkologii w Olsztynie ( Site 2486), Olsztyn, Warminsko-mazurskie

Wielkopolskie Centrum Onkologii im.M.Sklodowskiej-Curie ( Site 2484), Poznan, Wielkopolskie

Arkhangelsk Clinical Oncological Dispensary ( Site 2637), Arkhangelsk, Arkhangel Skaya Oblast

Republican Clinical Oncology Dispensary of Republic of Bashkortostan ( Site 2645), Ufa, Baskortostan, Respublika

Chelyabinsk Regional Clinical Center Oncology and Nuclear Medicine ( Site 2644), Chelyabinsk, Chelyabinskaya Oblast

Krasnoyarsk Regional Clinical oncology dispensary ( Site 2643), Krasnoyarsk, Krasnoyarskiy Kray

National Research Ogarev Mordovia State University ( Site 2648), Saransk, Mordoviya, Respublika

FSBI National Medical Oncology Research Center n.a. N.N. Blokhina ( Site 2634), Moscow, Moskva

Moscow Research Oncology Institute named after P.A. Hertsen ( Site 2631), Moscow, Moskva

Nizhegorodsky Regional Oncology Dispensary-chemotherapy department (Branch№1) ( Site 2639), Nizhniy Novgorod, Nizhegorodskaya Oblast

Samara Regional Clinical Oncology Center-Chemotherapy Dapartment ( Site 2649), Samara, Samarskaya Oblast

Scientific Research Oncology Institute n.a. N.N.Petrov ( Site 2636), Saint-Petersburg, Sankt-Peterburg

Republican Clinical Oncology Dispensary of Tatarstan MoH ( Site 2646), Kazan, Tatarstan, Respublika

Tomsk Scientific Research Institute of Oncology-Chemotherapy ( Site 2638), Tomsk, Tomskaya Oblast

Yaroslavl Regional SBIH Clinical Oncology Hospital ( Site 2641), Yaroslavl, Yaroslavskaya Oblast

Hospital Josep Trueta ( Site 2184), Girona, Gerona

Clinica Universitaria de Navarra ( Site 2181), Madrid, Madrid, Comunidad De

Hospital Vall D Hebron ( Site 2182), Barcelona, Not set

Hospital Clinic i Provincial ( Site 2185), Barcelona, Not set

Hospital Universitario Reina Sofia ( Site 2183), Cordoba, Not set

Hospital Clinico San Carlos ( Site 2187), Madrid, Not set

Hospital Universitario La Paz ( Site 2186), Madrid, Not set

Universitetssjukhuset i Linkoping. ( Site 2222), Linkoping, Ostergotlands Lan

Karolinska Universitetssjukhuset Solna ( Site 2220), Solna, Stockholms Lan

Blod-och Tumorsjukdomar ( Site 2221), Uppsala, Uppsala Lan

Changhua Christian Hospital ( Site 4095), Changhua, Not set

Taichung Veterans General Hospital ( Site 4094), Taichung, Not set

MacKay Memorial Hospital ( Site 4092), Taipei, Not set

Taipei Veterans General Hospital ( Site 4093), Taipei, Not set

Linkou Chang Gung Memorial Hospital ( Site 4091), Taoyuan, Not set

Baskent Adana Dr Turgut Noyan Uygulama ve Arastirma Merkezi ( Site 2355), Adana, Not set

Cukurova Uni. Tip Fakultesi ( Site 2353), Adana, Not set

Baskent Universitesi Ankara Hastanesi ( Site 2354), Ankara, Not set

Ankara Universitesi Tıp Fakultesi Hastanesi ( Site 2350), Ankara, Not set

Medipol Universite Hastanesi ( Site 2352), Istanbul, Not set

Ege University Medical Faculty ( Site 2351), Izmir, Not set

I.E.U. Medical Point Hastanesi ( Site 2356), Izmir, Not set

Chernihiv Medical Center of Modern Oncology ( Site 2368), Chernihiv, Chernihivska Oblast

Municipal Enterprise "Bukovinian сlinical oncology сenter" ( Site 2366), Chernivtsi, Chernivetska Oblast

SO Grigoriev Institute for Medical Radiology and Oncology of NAMS of Ukraine ( Site 2363), Kharkiv, Kharkivska Oblast

MNE "Khmelnytskyi regional antitumor center" ( Site 2365), Khmelnitskyi, Khmelnytska Oblast

LISOD - Israeli Oncological Hospital MedX-ray International Group, LLC ( Site 2364), Kiev, Kyivska Oblast

Lviv State Regional Oncological Center ( Site 2361), Lviv, Lvivska Oblast

The Municipal Enterprise Volyn Regional Medical Oncology Centre ( Site 2362), Lutsk, Volynska Oblast

Bristol Haematology and Oncology Centre ( Site 2244), Bristol, Bristol, City Of

Castle Hill Hospital-Academic Oncology ( Site 2252), Cottingham, East Riding Of Yorkshire

Beatson West of Scotland Cancer Centre ( Site 2247), Glasgow, Glasgow City

UCLH NHS Foundation Trust ( Site 2242), London, London, City Of

Royal Marsden NHS Foundation Trust ( Site 2248), London, London, City Of

Royal Marsden Hospital Sutton-Surrey ( Site 2241), Sutton, London, City Of

Leicester Royal Infirmary. Univ. Hosp. of Leicester NHS Trust ( Site 2249), Leicester, Not set

The Christie Hospital NHS Foundation Trust ( Site 2243), Manchester, Not set

Conditions: Endometrial Neoplasms

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Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma/PNET

NCT00392327

Active Not Recruiting

This phase III trial studies different chemotherapy and radiation therapy regimens to compare how well they work in treating young patients with newly diagnosed, previously untreated, high-risk medulloblastoma. Chemotherapy drugs, such as vincristine sulfate, cisplatin, cyclophosphamide, and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving more than one drug (combination... Read More

Gender:

ALL

Ages:

Between 3 years and 22 years

Trial Updated:

06/04/2025

Locations: Children's Hospital of Alabama, Birmingham, Alabama +184 locations

Children's Hospital of Alabama, Birmingham, Alabama

University of Alabama at Birmingham Cancer Center, Birmingham, Alabama

Providence Alaska Medical Center, Anchorage, Alaska

Banner Children's at Desert, Mesa, Arizona

Arkansas Children's Hospital, Little Rock, Arkansas

Loma Linda University Medical Center, Loma Linda, California

Miller Children's and Women's Hospital Long Beach, Long Beach, California

Children's Hospital Los Angeles, Los Angeles, California

Cedars Sinai Medical Center, Los Angeles, California

Valley Children's Hospital, Madera, California

UCSF Benioff Children's Hospital Oakland, Oakland, California

Kaiser Permanente-Oakland, Oakland, California

Children's Hospital of Orange County, Orange, California

Lucile Packard Children's Hospital Stanford University, Palo Alto, California

Sutter Medical Center Sacramento, Sacramento, California

University of California Davis Comprehensive Cancer Center, Sacramento, California

Rady Children's Hospital - San Diego, San Diego, California

UCSF Medical Center-Parnassus, San Francisco, California

UCSF Medical Center-Mission Bay, San Francisco, California

Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California

Children's Hospital Colorado, Aurora, Colorado

Connecticut Children's Medical Center, Hartford, Connecticut

Yale University, New Haven, Connecticut

Alfred I duPont Hospital for Children, Wilmington, Delaware

MedStar Georgetown University Hospital, Washington, District of Columbia

Children's National Medical Center, Washington, District of Columbia

Golisano Children's Hospital of Southwest Florida, Fort Myers, Florida

Memorial Regional Hospital/Joe DiMaggio Children's Hospital, Hollywood, Florida

Nemours Children's Clinic-Jacksonville, Jacksonville, Florida

University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida

Nicklaus Children's Hospital, Miami, Florida

AdventHealth Orlando, Orlando, Florida

Arnold Palmer Hospital for Children, Orlando, Florida

Nemours Children's Hospital, Orlando, Florida

Nemours Children's Clinic - Pensacola, Pensacola, Florida

Johns Hopkins All Children's Hospital, Saint Petersburg, Florida

Tampa General Hospital, Tampa, Florida

Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa, Florida

Saint Mary's Medical Center, West Palm Beach, Florida

Children's Healthcare of Atlanta - Arthur M Blank Hospital, Atlanta, Georgia

Memorial Health University Medical Center, Savannah, Georgia

Kapiolani Medical Center for Women and Children, Honolulu, Hawaii

Saint Luke's Cancer Institute - Boise, Boise, Idaho

Lurie Children's Hospital-Chicago, Chicago, Illinois

University of Illinois, Chicago, Illinois

University of Chicago Comprehensive Cancer Center, Chicago, Illinois

Loyola University Medical Center, Maywood, Illinois

Advocate Children's Hospital-Oak Lawn, Oak Lawn, Illinois

Advocate Children's Hospital-Park Ridge, Park Ridge, Illinois

Advocate Lutheran General Hospital, Park Ridge, Illinois

Saint Jude Midwest Affiliate, Peoria, Illinois

Southern Illinois University School of Medicine, Springfield, Illinois

Riley Hospital for Children, Indianapolis, Indiana

Ascension Saint Vincent Indianapolis Hospital, Indianapolis, Indiana

Blank Children's Hospital, Des Moines, Iowa

University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa

University of Kentucky/Markey Cancer Center, Lexington, Kentucky

Norton Children's Hospital, Louisville, Kentucky

Children's Hospital New Orleans, New Orleans, Louisiana

Eastern Maine Medical Center, Bangor, Maine

Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland

Walter Reed National Military Medical Center, Bethesda, Maryland

Massachusetts General Hospital Cancer Center, Boston, Massachusetts

Dana-Farber Cancer Institute, Boston, Massachusetts

Baystate Medical Center, Springfield, Massachusetts

C S Mott Children's Hospital, Ann Arbor, Michigan

Wayne State University/Karmanos Cancer Institute, Detroit, Michigan

Henry Ford Health Saint John Hospital, Detroit, Michigan

Michigan State University Clinical Center, East Lansing, Michigan

Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital, Grand Rapids, Michigan

Bronson Methodist Hospital, Kalamazoo, Michigan

Kalamazoo Center for Medical Studies, Kalamazoo, Michigan

Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis, Minnesota

University of Minnesota/Masonic Cancer Center, Minneapolis, Minnesota

Mayo Clinic in Rochester, Rochester, Minnesota

University of Mississippi Medical Center, Jackson, Mississippi

University of Missouri Children's Hospital, Columbia, Missouri

Children's Mercy Hospitals and Clinics, Kansas City, Missouri

Cardinal Glennon Children's Medical Center, Saint Louis, Missouri

Washington University School of Medicine, Saint Louis, Missouri

Mercy Hospital Saint Louis, Saint Louis, Missouri

Children's Hospital and Medical Center of Omaha, Omaha, Nebraska

University Medical Center of Southern Nevada, Las Vegas, Nevada

Sunrise Hospital and Medical Center, Las Vegas, Nevada

Alliance for Childhood Diseases/Cure 4 the Kids Foundation, Las Vegas, Nevada

Summerlin Hospital Medical Center, Las Vegas, Nevada

Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon, New Hampshire

Hackensack University Medical Center, Hackensack, New Jersey

Saint Barnabas Medical Center, Livingston, New Jersey

Morristown Medical Center, Morristown, New Jersey

Saint Peter's University Hospital, New Brunswick, New Jersey

Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital, New Brunswick, New Jersey

Newark Beth Israel Medical Center, Newark, New Jersey

Saint Joseph's Regional Medical Center, Paterson, New Jersey

Overlook Hospital, Summit, New Jersey

University of New Mexico Cancer Center, Albuquerque, New Mexico

Albany Medical Center, Albany, New York

Montefiore Medical Center - Moses Campus, Bronx, New York

Roswell Park Cancer Institute, Buffalo, New York

NYU Langone Hospital - Long Island, Mineola, New York

The Steven and Alexandra Cohen Children's Medical Center of New York, New Hyde Park, New York

Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York

Mount Sinai Hospital, New York, New York

NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York, New York

Memorial Sloan Kettering Cancer Center, New York, New York

University of Rochester, Rochester, New York

Stony Brook University Medical Center, Stony Brook, New York

State University of New York Upstate Medical University, Syracuse, New York

UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina

Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina

Novant Health Presbyterian Medical Center, Charlotte, North Carolina

Wake Forest University Health Sciences, Winston-Salem, North Carolina

Sanford Broadway Medical Center, Fargo, North Dakota

Children's Hospital Medical Center of Akron, Akron, Ohio

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

Rainbow Babies and Childrens Hospital, Cleveland, Ohio

Cleveland Clinic Foundation, Cleveland, Ohio

Nationwide Children's Hospital, Columbus, Ohio

Dayton Children's Hospital, Dayton, Ohio

ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital, Toledo, Ohio

Mercy Children's Hospital, Toledo, Ohio

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Legacy Emanuel Children's Hospital, Portland, Oregon

Legacy Emanuel Hospital and Health Center, Portland, Oregon

Oregon Health and Science University, Portland, Oregon

Lehigh Valley Hospital-Cedar Crest, Allentown, Pennsylvania

Lehigh Valley Hospital - Muhlenberg, Bethlehem, Pennsylvania

Geisinger Medical Center, Danville, Pennsylvania

Penn State Children's Hospital, Hershey, Pennsylvania

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

Saint Christopher's Hospital for Children, Philadelphia, Pennsylvania

Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania

Medical University of South Carolina, Charleston, South Carolina

Prisma Health Richland Hospital, Columbia, South Carolina

BI-LO Charities Children's Cancer Center, Greenville, South Carolina

Greenville Cancer Treatment Center, Greenville, South Carolina

Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota

T C Thompson Children's Hospital, Chattanooga, Tennessee

East Tennessee Childrens Hospital, Knoxville, Tennessee

The Children's Hospital at TriStar Centennial, Nashville, Tennessee

Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee

Texas Tech University Health Sciences Center-Amarillo, Amarillo, Texas

Dell Children's Medical Center of Central Texas, Austin, Texas

Driscoll Children's Hospital, Corpus Christi, Texas

Medical City Dallas Hospital, Dallas, Texas

UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas

Cook Children's Medical Center, Fort Worth, Texas

Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas

M D Anderson Cancer Center, Houston, Texas

Covenant Children's Hospital, Lubbock, Texas

UMC Cancer Center / UMC Health System, Lubbock, Texas

Children's Hospital of San Antonio, San Antonio, Texas

Methodist Children's Hospital of South Texas, San Antonio, Texas

University of Texas Health Science Center at San Antonio, San Antonio, Texas

Scott and White Memorial Hospital, Temple, Texas

Primary Children's Hospital, Salt Lake City, Utah

University of Vermont and State Agricultural College, Burlington, Vermont

Inova Fairfax Hospital, Falls Church, Virginia

Children's Hospital of The King's Daughters, Norfolk, Virginia

Virginia Commonwealth University/Massey Cancer Center, Richmond, Virginia

Carilion Children's, Roanoke, Virginia

Seattle Children's Hospital, Seattle, Washington

Providence Sacred Heart Medical Center and Children's Hospital, Spokane, Washington

Mary Bridge Children's Hospital and Health Center, Tacoma, Washington

Madigan Army Medical Center, Tacoma, Washington

West Virginia University Charleston Division, Charleston, West Virginia

West Virginia University Healthcare, Morgantown, West Virginia

Saint Vincent Hospital Cancer Center Green Bay, Green Bay, Wisconsin

Marshfield Medical Center-Marshfield, Marshfield, Wisconsin

Children's Hospital of Wisconsin, Milwaukee, Wisconsin

Women's and Children's Hospital-Adelaide, North Adelaide, South Australia

Princess Margaret Hospital for Children, Perth, Western Australia

University of Alberta Hospital, Edmonton, Alberta

British Columbia Children's Hospital, Vancouver, British Columbia

CancerCare Manitoba, Winnipeg, Manitoba

IWK Health Centre, Halifax, Nova Scotia

McMaster Children's Hospital at Hamilton Health Sciences, Hamilton, Ontario

Children's Hospital of Eastern Ontario, Ottawa, Ontario

Hospital for Sick Children, Toronto, Ontario

The Montreal Children's Hospital of the MUHC, Montreal, Quebec

Centre Hospitalier Universitaire Sainte-Justine, Montreal, Quebec

Saskatoon Cancer Centre, Saskatoon, Saskatchewan

CHU de Quebec-Centre Hospitalier de l'Universite Laval (CHUL), Quebec, Not set

Dutch Childhood Oncology Group, Utrecht, Not set

University Pediatric Hospital, San Juan, Not set

Conditions: Anaplastic Medulloblastoma, Medulloblastoma

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