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Paclitaxel Treatment Options in Canada
A collection of 344 research studies where Paclitaxel is the interventional treatment. These studies are located in the Canada . Paclitaxel is used for conditions such as Breast Cancer, Ovarian Cancer and Non-Small Cell Lung Cancer.
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Effect of Tumor Treating Fields (TTFields, 200 kHz) Concomitant With Weekly Paclitaxel for the Treatment of Recurrent Ovarian Cancer (ENGOT-ov50 / GOG-3029 / INNOVATE-3)
Completed
The study is a prospective, randomized controlled phase III trial aimed to test the efficacy and safety of Tumor Treating Fields (TTFields) concomitant with weekly paclitaxel for the treatment of recurrent ovarian cancer . The device is an experimental, portable, battery operated device for chronic administration of alternating electric fields (termed TTFields or TTF) to the region of the malignant tumor, by means of surface, insulated electrode arrays.
The study is a prospective, randomized controlled phase III trial aimed to test the efficacy and safety of Tumor Treating Fields (TTFields) concomitant with weekly paclitaxel for the treatment of recurrent ovarian cancer . The device is an experimental, portable, battery operated device for chronic administration of alternating electric fields (termed TTFields or TTF) to the region of the malignant tumor, by means of surface, insulated electrode arrays. Read Less
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
03/28/2024
Locations: Arizona Oncology- Biltmore Cancer Center, Phoenix, Arizona +118 locations
Arizona Oncology- Biltmore Cancer Center, Phoenix, Arizona
Arizona Oncology, Tucson, Arizona
University of California, La Jolla, California
Hoag Memorial Hospital Presbyterian, Newport Beach, California
California Pacific Medical Center- Pacific Campus, San Francisco, California
Olive View - UCLA Medical Center, Sylmar, California
Rocky Mountain Cancer Centers, Aurora, Colorado
University of Colorado Denver, Aurora, Colorado
Rocky Mountain Cancer Centers, Boulder, Colorado
Rocky Mountain Cancer Centers, Colorado Springs, Colorado
Rocky Mountain Cancer Centers, Denver, Colorado
Rocky Mountain Cancer Centers, Denver, Colorado
Rocky Mountain Cancer Centers, Lakewood, Colorado
Rocky Mountain Cancer Centers, Littleton, Colorado
Rocky Mountain Cancer Centers, Lone Tree, Colorado
Rocky Mountain Cancer Centers, Longmont, Colorado
Rocky Mountain Cancer Centers, Parker, Colorado
Rocky Mountain Cancer Centers, Pueblo, Colorado
Rocky Mountain Cancer Centers, Thornton, Colorado
Broward Health Medical Center, Fort Lauderdale, Florida
AdventHealth Cancer Institute, Orlando, Florida
Northeast Georgia Medical Center, Gainesville, Georgia
Rush University Cancer Center - Chicago and Innovation, Chicago, Illinois
Des Moines Oncology Research Association, Des Moines, Iowa
Norton Cancer Institute, Louisville, Kentucky
Maryland Oncology Hematology, P.A., Silver Spring, Maryland
Lahey Hospital & Medical Center, Burlington, Massachusetts
Minnesota Oncology Hematology, PA, Saint Paul, Minnesota
Washington University School of Medicine in St. Louis, Saint Louis, Missouri
Methodist Estabrook Cancer Center, Omaha, Nebraska
Women's Cancer Center of Nevada, Las Vegas, Nevada
Center of Hope at Renown Medical Center, Reno, Nevada
MD Anderson Cancer Center at Cooper, Camden, New Jersey
The Valley Hospital, Paramus, New Jersey
Wake Forest Baptist Medical Center, Winston-Salem, North Carolina
Miami Valley Hospital South, Centerville, Ohio
The Ohio State University Wexner Medical Center, Columbus, Ohio
Northwest Cancer Specialists, PC, Portland, Oregon
West Penn OB/GYN, Pittsburgh, Pennsylvania
UPMC Cancer Center, Pittsburgh, Pennsylvania
Abington Hospital- Asplundh Cancer Pavilion, Willow Grove, Pennsylvania
Women & Infants Hospital of Rhode Island, Providence, Rhode Island
Sanford Gynecologic Oncology Clinic, Sioux Falls, South Dakota
Texas Oncology Austin-Balcones, Austin, Texas
Texas Oncology Austin-Midtown, Austin, Texas
Texas Oncology Austin-North Austin, Austin, Texas
University of Texas Southwestern Medical Center, Dallas, Texas
Texas Oncology, Dallas, Texas
Texas Oncology-Fort Worth, Fort Worth, Texas
The University of Texas Medical School at Houston, Houston, Texas
Texas Oncology-McAllen, McAllen, Texas
Texas Oncology San Antonio Medical Center, San Antonio, Texas
Texas Oncology - Sugar Land, Sugar Land, Texas
Texas Oncology, The Woodlands, Texas
Texas Oncology-Tyler, Tyler, Texas
Texas Oncology-Deke Slayton Cancer Center, Webster, Texas
Virginia Oncology Associates, Norfolk, Virginia
Carilion Clinic-Gynecologic Oncology, Roanoke, Virginia
Multicare Institute for Research and Innovation, Tacoma, Washington
KH der Barmherzigen Brüder Graz, Graz, Not set
Univ.-Klinik für Gynäkologie und Geburtshilfe, Graz, Not set
Univ.-Klinik für Gynäkologie und Geburtshilfe, Innsbruck, Innsbruck, Not set
Landesfrauenklinik Salzburg, Salzburg, Not set
Imelda Ziekenhuis Bonheiden, Bonheiden, Not set
Cliniques Universitaires Saint Luc, Institut Roi Albert II, Brussel, Not set
Grand Hôpital de Charleroi, Oncologie-Hématologie, Charleroi, Not set
AZ Maria Middelares, Clinical Trial Unit Medical Oncology - Integrated Cancer Center Ghent, Gent, Not set
UZ Gent, Gent, Not set
University Hospitals Leuven, Leuven Cancer Institute, Leuven, Not set
CHU Ambroise Paré, Mons, Not set
CHU UCL Namur - Site Ste Elisabeth, Namur, Not set
CancerCare Manitoba, Winnipeg, Manitoba
Centre Hospitalie, Montréal, Quebec
Tom Baker Cancer Center, Calgary, Not set
McGill University Health Centre, Montréal, Not set
Jewish General Hospital, Montréal, Not set
Onkologická Klinika Fakultní nemocnice Olomouc, Olomouc, Not set
University Hospital Ostrava, Ostrava-Poruba, Not set
Gynekologicko-porodnická klinika, Fakultní nemocnice Královské Vinohrady, Praha 10, Not set
Gynekologicko-porodnická klinika 1. LF UK a VFN, Praha 2, Not set
Gynekologicko-porodnické oddělení - Nemocnice České Budějovice a.s., České Budějovice, Not set
Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum, Klinik für Gynäkologie, Berlin, Not set
Universitätsklinikum Carl Gustav Carus, Dresden, Not set
Horst-Schmidt-Kliniken, Gynecology and Gynecologic, Oncology Department, Wiesbaden, Not set
Semmelweis University, Budapest, Not set
Nőgyógyászati Osztály, Országos Onkológiai Intézet, Budapest, Not set
Szuleszeti és Nogyogyaszati Klinika, Debrecen, Not set
Hillel Yaffe Medical Center, Hadera, Not set
Saare Zedek Medical Center - Gyneco-Oncology, Jerusalem, Not set
Oncology Institute, Galilee Medical Center, Nahariya, Not set
Gyneco-Oncology Chaim Sheba Medical Center, Ramat Gan, Not set
Policlinico S. Orsola-Malpighi, SSD Oncologia Medica Addarii, Bologna, Not set
Presidio Ospedaliero Antonio Perrino - ASL Brindisi, Brindisi, Not set
ASST Lecco - Ospedale Manzoni, Dipartimento Oncologico, Lecco, Not set
Dipartimento Medicina e Chirurgia, Università Milano-Bicocca, Direttore Programma Ginecologia Oncologica, Istituto Europeo Oncologia, Milano, Not set
IRCCS Ospedale San Raffaele, U.O. Ginecologia-Ematologia e TMO, Milano, Not set
Istituto Nazionale Tumori IRCCS Fondazione Pascale, Napoli, Not set
Fondazione Policlinico Universitario Gemelli, Roma, Not set
University Saint Anna, Torino, Not set
Amsterdam Universitair Medische centra, Amsterdam, Not set
University Medical Center Utrech, Utrecht, Not set
Szpitale Pomorskie Sp. z o.o., Gdynia, Not set
Oddział Kliniczny Chirurgii Ogólnej i Onkologicznej, Szpital Św. Rafała, Kraków, Not set
Uniwersytet Medyczny w Lublinie, I Klinika Ginekologii Onkologicznej i Ginekologii, Lublin, Not set
Samodzielny Publiczny Zakład Opieki Zdrowotnej MSWiA z Warmińsko-Mazurskim Centrum Onkologii w Olsztynie, Oddział Kliniczny Onkologii i Immunoonkologii z Ośrodkiem Dziennym Terapii Onkologicznej, Olsztyn, Not set
Oddział Ginekologii Onkologicznej Katedry i Kliniki Onkologii Uniwersytetu Medycznego w Poznaniu, Poznań, Not set
Samodzielny Publiczny Szpital Kliniczny Nr 2 PUM w Szczecinie, Klinika Ginekologii Operacyjnej i Onkologii Ginekologicznej Dorosłych i Dziewcząt, Szczecin, Not set
Szpital Kliniczny im. ks. Anny Mazowieckiej, Warsaw, Not set
Servicio de Oncología Médica, Hospital Universitario Quirón Dexeus, Barcelona, Not set
lnstitut Catala d'Oncologia, Hospital Universitario Dr. Josep Trueta, Servicio de Oncologia,, Girona, Not set
Clinica Universidad de Navarra en Madrid, Madrid, Not set
Hospital MD Anderson Cancer Center, Madrid, Not set
Hospital Universitario Ramon y Cajal, Servicio de Oncologia Médica, Madrid, Not set
Hospital 12 de Octubre. Servicio Oncología Médica, Madrid, Not set
Fundació Institut d'Investigació Sanitària Illes Balears - IdISBa, Hospital Universitari Son Espases, Palma De Mallorca, Not set
Gynecological Tumor Center, University Hospital Basel, Basel, Not set
IOSI Bellinzona, Oncology Institute of Southern Switzerland, Ospedale San Giovanni, Bellinzona, Not set
Kantonsspital Frauenfeld - Frauenklinik, Frauenfeld, Not set
UniversitätsSpital Zürich - Klinik für Gynäkologie, Zürich, Not set
Conditions: Ovarian Cancer
Phase 1 Study of RP-6306 With Carboplatin and Paclitaxel in TP53 Ovarian and Uterine Cancer
Active Not Recruiting
This is a phase 1 study to evaluate investigational drug RP-6306 in combination with carboplatin and paclitaxel in patients with TP53 mutated ovarian or uterine cancer. The dose escalation part of the study will determine the maximum tolerated dose (MTD) and recommended Phase 2 Dose (RP2D) and schedule of RP-6306 in combination with carboplatin and paclitaxel and the dose expansion will further assess the safety and tolerability as well as determine the preliminary efficacy of RP-6306 in combina... Read More
This is a phase 1 study to evaluate investigational drug RP-6306 in combination with carboplatin and paclitaxel in patients with TP53 mutated ovarian or uterine cancer. The dose escalation part of the study will determine the maximum tolerated dose (MTD) and recommended Phase 2 Dose (RP2D) and schedule of RP-6306 in combination with carboplatin and paclitaxel and the dose expansion will further assess the safety and tolerability as well as determine the preliminary efficacy of RP-6306 in combination with carboplatin and paclitaxel. Read Less
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
03/20/2024
Locations: Princess Margaret Cancer Centre, Toronto, Ontario
Princess Margaret Cancer Centre, Toronto, Ontario
Conditions: Recurrent Ovarian Cancer, Recurrent Uterine Cancer, Metastatic Cancer, Advanced Cancer
A Study of Atezolizumab and Paclitaxel Versus Placebo and Paclitaxel in Participants With Previously Untreated Locally Advanced or Metastatic Triple Negative Breast Cancer (TNBC)
Completed
This Phase 3, multicenter, randomized, double-blind, placebo controlled study is designed to evaluate the efficacy and safety of atezolizumab (MPDL3280A, an anti-programmed death-ligand 1 \[PD-L1\] antibody) administered in combination with paclitaxel compared with placebo in combination with paclitaxel in participants with previously untreated, inoperable locally advanced or metastatic, centrally confirmed TNBC. Participants will be randomized in a 2:1 ratio to receive atezolizumab or placebo p... Read More
This Phase 3, multicenter, randomized, double-blind, placebo controlled study is designed to evaluate the efficacy and safety of atezolizumab (MPDL3280A, an anti-programmed death-ligand 1 \[PD-L1\] antibody) administered in combination with paclitaxel compared with placebo in combination with paclitaxel in participants with previously untreated, inoperable locally advanced or metastatic, centrally confirmed TNBC. Participants will be randomized in a 2:1 ratio to receive atezolizumab or placebo plus paclitaxel until disease progression or unacceptable toxicity or end of study, whichever occurs first (maximum up to approximately 40 months). In addition, the Sponsor may decide to terminate the study at any time. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/01/2024
Locations: Stanford Cancer Center, Stanford, California +160 locations
Stanford Cancer Center, Stanford, California
Florida Cancer Specialists; Department of Oncology, Fort Myers, Florida
Florida Cancer Specialist, North Region, Saint Petersburg, Florida
Northwest Georgia Oncology Centers PC - Marietta, Marietta, Georgia
HCA Midwest Health, Kansas City, Missouri
The Valley Hospital, Paramus, New Jersey
Magee-Woman's Hospital, Pittsburgh, Pennsylvania
Tennessee Oncology; Sarah Cannon Research Institute, Nashville, Tennessee
Centro Oncologico Riojano Integral (CORI), La Rioja, Not set
Santa Casa de Misericordia de Salvador, Salvador, BA
Centro de Pesquisas Clinicas em Oncologia - CPCO, Cachoeiro de Itapemirim, ES
Hospital Araujo Jorge; Departamento de Ginecologia E Mama, Goiania, GO
Hospital Nossa Senhora da Conceicao, Porto Alegre, RS
Hospital Sao Lucas - PUCRS, Porto Alegre, RS
Hospital Perola Byington, Sao Paulo, SP
Tom Baker Cancer Centre-Calgary, Calgary, Alberta
Cross Cancer Institute, Edmonton, Alberta
Kingston General Hospital, Kingston, Ontario
Grand River Hospital, Kitchener, Ontario
London Regional Cancer Centre, London, Ontario
Sunnybrook Odette Cancer Centre, Toronto, Ontario
McGill University; Glen Site; Oncology, Montreal, Quebec
Hopital du Saint Sacrement, Quebec City, Quebec
Centre Hospitalier Universitaire de Sherbrooke - Hopital Fleurimont, Sherbrooke, Quebec
Cancer Hospital Chinese Academy of Medical Sciences., Beijing, Not set
Beijing Union Hospital, Beijing, Not set
West China Hospital, Sichuan University; Department of Breast, Chengdu, Not set
Sun Yat-sen Memorial Hospital, Guangzhou, Not set
Harbin Medical University Cancer Hospital, Harbin, Not set
Shandong Cancer Hospital, Jinan, Not set
Jiangsu Province Hospital (the First Affiliated Hospital With Nanjing Medical University), Nanjing City, Not set
Jiangsu Cancer Hospital, Nanjing City, Not set
Fudan University Shanghai Cancer Center, Shanghai City, Not set
Shanghai Jiao Tong University School of Medicine (SJTUSM) - Ruijin Hospital (GuangCi Hospital), Shanghai, Not set
Liaoning cancer Hospital & Institute, Shenyang, Not set
Hebei Medical University Fourth Hospital;(Tumor Hospital of Hebei Province), Shijiazhuang, Not set
Tianjin Medical University Cancer Institute & Hospital, Tianjin, Not set
The Second Affiliated Hospital of Xi'an Jiao Tong University, Xi'an City, Not set
First Affiliated Hospital of Medical College of Xi'an Jiaotong University, Xi'an, Not set
Zhejiang Cancer Hospital, Zhejiang, Not set
Henan Cancer Hospital, Zhengzhou, Not set
Clinical Hospital Centre Zagreb, Zagreb, Not set
Fakultni Nemocnice Hradec Kralove; Dept of Radiotherapy & Oncology, Hradec Kralove, Not set
Fakultni nemocnice Olomouc; Onkologicka klinika, Olomouc, Not set
Fakultni nemocnice Ostrava; Klinika onkologicka FNO a LF OU, Ostrava-Poruba, Not set
Fakultni Poliklinika Vseobecne Fakultni Niemocnice; Onkologicka Klinika, Praha 2, Not set
Clinique Sainte Catherine; Hopital De Semaine, Avignon, Not set
HOPITAL JEAN MINJOZ; Oncologie, Besancon, Not set
Polyclinique Bordeaux Nord Aquitaine, Bordeaux, Not set
Hopital Morvan, Brest, Not set
CHD Les Oudairies, La Roche Sur Yon, Not set
Centre Oscar Lambret; Senologie, Lille, Not set
Centre Leon Berard; Departement Oncologie Medicale, Lyon, Not set
Centre D'Oncologie de Gentilly; Oncology, Nancy, Not set
Hopital Caremeau; Hematologie Oncologie, Nimes, Not set
Hopital Tenon, Paris, Not set
Institut Curie; Oncologie Medicale, Paris, Not set
Hopital Saint Louis, Service D Oncologie Medicale, Paris, Not set
Ch Pitie Salpetriere; Oncologie Medicale, Paris, Not set
Centre Eugene Marquis; Service d'oncologie, Rennes, Not set
Centre Paul Strauss; Oncologie Medicale, Strasbourg, Not set
Institut Claudius Regaud; Departement Oncologie Medicale, Toulouse, Not set
Institut Gustave Roussy; Sitep, VILLEJUIF Cedex, Not set
Ambulantes Tumorzentrum Spandau; Dres. Benno Mohr und Uwe Peters, Berlin, Not set
Onkologische Schwerpunktpraxis Bielefeld, Bielefeld, Not set
Klinikum Essen-Mitte Ev. Huyssens-Stiftung / Knappschafts GmbH; Klinik für Senologie / Brustzentrum, Essen, Not set
HOPA im Struensee-Haus, Dres. Erik Engel, Wiebke Hollburg, Hamburg, Not set
Nationales Centrum für Tumorerkrankungen (NCT) ; Gyn. Onk. Frauenklinik; Uniklinikum Heidelberg, Heidelberg, Not set
St. Elisabeth Krankenhaus Köln GmbH; Gynäkologie und Geburtshilfe, Koeln, Not set
Universitätsmedizin Mainz; Klinik u. Poliklinik f. Geburtshilfe u. Frauenheilkunde, Mainz, Not set
OnkoNet Marburg GmbH, Marburg, Not set
Klinik & Poliklinik für Frauenheilkunde und Geburtshilfe, Campus Innenstadt, München, Not set
Gemeinschaftspraxis für Hämatologie und Onkologie, Münster, Not set
Klinikum Ernst von Bergmann; Frauenklinik, Potsdam, Not set
Dres. Helmut Forstbauer, Carsten Ziske und Kollegen; Onkologische Schwerpunktpraxis, Troisdorf, Not set
Universitätsklinik Tübingen; Frauenklinik, Tübingen, Not set
Anticancer Hospital Ag. Savas ; 2Nd Dept. of Oncology - Internal Medicine, Athens, Not set
ARETAIEION UNIVERSITY HOSPITAL; oncology unit, Athens, Not set
Agioi Anargyroi Cancer Hospital; 2Nd Oncology Dept., Kifisia, Not set
Papageorgiou General Hospital; Medical Oncology, Thessaloniki, Not set
Yashoda Hospital, Hyderabad, Andhra Pradesh
Dr. B L Kapur Memorial Hospital; BLK Cancer Centre, New Delhi, Delhi
Indraprastha Apollo Hospitals, New Delhi, Delhi
Rajiv Gandhi Cancer Inst.&Research Center; Medical Oncology, New Delhi, Delhi
Max Super Speciality Hospital; Medical Oncology, North WEST Delhi, Delhi
Manipal Hospital; Department of Oncology, Bangalore, Karnataka
Tata Memorial Hospital; Dept of Medical Oncology, Mumbai, Maharashtra
Jehangir Hospital, Pune, Maharashtra
Apollo Speciality Hospital, Chennai, Tamil NADU
Apollo Gleneagles Hospitals, Kolkata, WEST Bengal
TATA Medical Centre; Medical Oncology, Kolkata, WEST Bengal
MAX Balaji Hospital, Delhi, Not set
Hadassah Ein Karem Hospital; Oncology Dept, Jerusalem, Not set
Rabin MC; Davidof Center - Oncology Institute, Petach Tikva, Not set
Sheba Medical Center, Ramat Gan, Not set
Rambam Health Corporation; Oncology Institute, Rambam, Not set
Kaplan Medical Center, Rehovot, Not set
Tel Aviv Sourasky Medical Ctr; Oncology, Tel Aviv, Not set
Assaf Harofeh; Oncology, Zerifin, Not set
Fondazione Università G. D'Annunzio; Clinical Research Center (CRC); Centro Studi (CESI), Chieti, Abruzzo
Presidio Ospedaliero S. Giovanni Di Dio; U.O. Di Oncologia, Frattamaggiore, Campania
Azienda Ospedaliera Universitaria Federico II, Napoli, Campania
Istituto Nazionale Tumori Fondazione G. Pascale, Napoli, Campania
Azienda Ospedaliero - Universitaria di Modena Policlinico, Modena, Emilia-Romagna
Universita Campus Bio-Medico di Roma (UCBM), Roma, Lazio
IRCCS Istituto Regina Elena (IFO); Oncologia Medica B, Roma, Lazio
Azienda Policlinico Umberto I, Roma, Lazio
A.O. Universitaria S. Martino Di Genova, Genova, Liguria
Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII (Presidio Papa Giovanni XXIII), Bergamo, Lombardia
Asst Degli Spedali Civili Di Brescia, Brescia, Lombardia
Hospital San Raffaele, Milano, Lombardia
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Lombardia
IEO Istituto Europeo di Oncologia;Divisione Oncologia Medica, Milano, Lombardia
IRCCS Istituto Clinico Humanitas; Oncologia, Rozzano (MI), Lombardia
Fondazione Del Piemonte Per L'oncologia IRCC Di Candiolo, Candiolo, Piemonte
Ospedale S. Vincenzo; Oncologia Medica, Taormina, Sicilia
Azienda Ospedaliero-Universitaria Careggi; SOD Radioterapia, Firenze, Toscana
Ospedale Civile; Unita Operativa Di Oncologia Medica, Livorno, Toscana
IOV - Istituto Oncologico Veneto - IRCCS; Oncologia Medica II, Padova, Veneto
Gunma Prefectural Cancer Center, Gunma, Not set
Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Not set
Sagara Hospital, Kagoshima, Not set
Kanagawa Cancer Center, Kanagawa, Not set
Tokai University Hospital, Kanagawa, Not set
Niigata Cancer Center Hospital, Niigata, Not set
Naha-nishi Clinic, Okinawa, Not set
Osaka International Cancer Institute, Osaka, Not set
Saitama Cancer Center, Saitama, Not set
The Cancer Institute Hospital of JFCR, Tokyo, Not set
Centre Hospitalier Universitaire Mohamed VI; Oncologie-Hématologie, Marrakech, Not set
Institut National D'oncologie Sidi Mohammed Ben Abdellah; Anatomopathologie, Rabat, Not set
Prof. Dr. I. Chiricuta Institute of Oncology, Cluj Napoca, Not set
Centrul de Oncologie Sfantul Nectarie, Craiova, Not set
Russian Oncology Research Center n.a. N.N. Blokhin, Moscow, Moskovskaja Oblast
Petrov Research Inst. of Oncology, Sankt Petersburg, Not set
King Fahad Specialist Hospital; Oncology, Dammam, Not set
International Medical Center (IMC), Jeddah, Not set
King Fahad Medical City; Gastroentrology, Riyadh, Not set
Narodny Onkologicky Ustav; Oddelenie klinickej onkologie A, Bratislava, Not set
POKO Poprad; Department of Oncology, Poprad, Not set
Wilgers Oncology Centre, Pretoria, Not set
Private Oncology Centre, Pretoria, Not set
Sandton Oncology Medical Group, Sandton, Not set
Complejo Hospitalario Universitario A Coruña (CHUAC); Servicio de Oncologia, A Coruña, LA Coruña
Hospital Clínic i Provincial; Servicio de Hematología y Oncología, Barcelona, Not set
Hospital Universitario de Fuenlabrada; Servicio de Oncologia, Madrid, Not set
Hospital Universitario Virgen Macarena; Servicio de Oncologia, Sevilla, Not set
Hospital Universitario Virgen del Rocio; Servicio de Oncologia, Sevilla, Not set
Adana Baskent University Medical Faculty; Oncology, Adana, Not set
Ankara Bilkent City Hospital, Ankara, Not set
Uludag University Medical Faculty; Internal Medicine, Bursa, Not set
Dicle Uni Medical Faculty; Internal Medicine, Diyarbakir, Not set
Trakya Universitesi Tip Fakultesi, Medikal Onkoloji Bilim Dali, Balkan Yerleskesi, Edirne, Not set
Izmir Ataturk Training and Research Hospital, Izmir, Not set
Kocaeli University Faculty of Medicine; Medical oncology, Izmit, Not set
Goztepe Prof.Dr. Suleyman Yalcin City Hospital; Clinical Oncology, Kadiköy, Not set
Guys and St Thomas NHS Foundation Trust, Guys Hospital, London, Not set
Christie Hospital, Manchester, Not set
Mount Vernon Cancer Centre, Northwood, Not set
K hospital, Hanoi, Not set
Hochiminh city oncology hospital, Hochiminh city, Not set
Conditions: Triple-Negative Breast Cancer
A Study of Trastuzumab Emtansine (T-DM1) Plus Pertuzumab/Pertuzumab Placebo Versus Trastuzumab [Herceptin] Plus a Taxane in Participants With Metastatic Breast Cancer (MARIANNE)
Completed
This randomized, 3-arm, multicenter, phase III study will evaluate the efficacy and safety of trastuzumab emtansine (T-DM1) with pertuzumab or trastuzumab emtansine (T-DM1) with pertuzumab-placebo (blinded for pertuzumab), versus the combination of trastuzumab (Herceptin) plus taxane (docetaxel or paclitaxel) in participants with HER2-positive progressive or recurrent locally advanced or previously untreated metastatic breast cancer. Participants will be randomized to 1 of 3 treatment arms (Arms... Read More
This randomized, 3-arm, multicenter, phase III study will evaluate the efficacy and safety of trastuzumab emtansine (T-DM1) with pertuzumab or trastuzumab emtansine (T-DM1) with pertuzumab-placebo (blinded for pertuzumab), versus the combination of trastuzumab (Herceptin) plus taxane (docetaxel or paclitaxel) in participants with HER2-positive progressive or recurrent locally advanced or previously untreated metastatic breast cancer. Participants will be randomized to 1 of 3 treatment arms (Arms A, B or C). Arm A will be open-label, whereas Arms B and C will be blinded. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/29/2024
Locations: Uni of Arkansas For Medical Sciences; Arkansas Cancer Research Center, Little Rock, Arkansas +256 locations
Uni of Arkansas For Medical Sciences; Arkansas Cancer Research Center, Little Rock, Arkansas
Scripps Cancer Center, La Jolla, California
University of California; Moores Cancer Center, La Jolla, California
Clnc L Trials & Rsch Assoc-Inc, Montebello, California
Southern California Kaiser Permanente, San Diego, California
Breastlink Medical Group Inc, Santa Ana, California
Kaiser Permanente; Oncology Clinical Trials, Vallejo, California
Smilow Cancer Hospital at Yale New Haven, New Haven, Connecticut
Innovative Medical Research of South Florida, Aventura, Florida
Northwest Oncology/ Hematology Assoc., Coral Springs, Florida
Florida Cancer Specialists; SCRI, Fort Myers, Florida
Mayo Clinic-Jacksonville, Jacksonville, Florida
Uni of Miami School of Medicine; Sylvester Comprehensive Cancer Center, Miami, Florida
University Cancer & Blood Center, LLC; Research, Athens, Georgia
Cancer Research Center of Hawaii; Clinical Sciences, Honolulu, Hawaii
Mountain States Tumor Inst., Boise, Idaho
Uni of Chicago, Chicago, Illinois
Decatur Memorial Hospital, Decatur, Illinois
Ingalls Memorial Hospital, Harvey, Illinois
Loyola University Med Center, Maywood, Illinois
Illinois Cancer Care, Peoria, Illinois
Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, Indiana
Horizon Oncology Research, Inc., Lafayette, Indiana
James Graham Brown Cancer Center, University of Louisville, Louisville, Kentucky
New England Cancer Specialists, Scarborough, Maine
Anne Arundel Health System Research Instit-Annapolis Oncology Ctr, Annapolis, Maryland
Boston Medical Center, Boston, Massachusetts
Spectrum Health Grand Rapids, Grand Rapids, Michigan
University of Minnesota., Minneapolis, Minnesota
Mayo Clinic Rochester, Rochester, Minnesota
St. John'S Mercy Medical Center; David C. Pratt Cancer Center, Saint Louis, Missouri
Mercy Clinic Cancer & Hematology, Springfield, Missouri
Dartmouth Hitchcock Med Center, Lebanon, New Hampshire
Hackensack Uni Medical Center; Northern Nj Cancer Center, Hackensack, New Jersey
Cancer Inst. of New Jersey, New Brunswick, New Jersey
San Juan Oncology Associates, Farmington, New Mexico
Queens Medical Associates, Fresh Meadows, New York
Queens Hospital Center, Jamaica, New York
Arena Oncology Associates, Lake Success, New York
Icahn School of Medicine at Mount Sinai, New York, New York
Weill Medical College of Cornell Uni, New York, New York
Carolinas Hem-Oncology Assoc, Charlotte, North Carolina
Carolina Oncology Specialists, PA - Hickory, Hickory, North Carolina
Marion L. Shepard Cancer Center, Washington, North Carolina
Sanford Roger Maris Cancer Center, Fargo, North Dakota
Oncology Hematology Care - SCRI, Cincinnati, Ohio
Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania
Charleston Oncology, P .A, Charleston, South Carolina
Medical University of SC (MUSC), Charleston, South Carolina
South Carolina Oncology Associates - SCRI, Columbia, South Carolina
Avera Cancer Institute, Sioux Falls, South Dakota
SCRI Tennessee Oncology Chattanooga, Chattanooga, Tennessee
West Clinic, Germantown, Tennessee
Tennessee Onc., PLLC - SCRI, Nashville, Tennessee
Vanderbilt-Ingram Cancer Ctr, Nashville, Tennessee
The Don & Sybil Harrington Cancer Center; Department of Clinical Research, Amarillo, Texas
Uni of Texas Southwestern Medical Center, Dallas, Texas
Uni of Texas - Md Anderson Cancer Center; Dept of Breast Medical Oncology, Houston, Texas
Northern Utah Associates, Ogden, Utah
The Providence Regional Medical Center Everett, Everett, Washington
University of Washington, Seattle, Washington
Northwest Medical Specialties, Tacoma, Washington
Fundación Investigar, Buenos Aires, Not set
Centro Medico San Roque, San Miguel de Tucuman, Not set
Mater Misericordiae Hospital; Chemotherapy Cottage, Sydney, New South Wales
Calvary Mater Newcastle; Medical Oncology, Waratah, New South Wales
Wesley Medical Centre; Clinic For Haematology and Oncology, Auchenflower, Queensland
Royal Adelaide Hospital; Oncology, Adelaide, South Australia
Peter Maccallum Cancer Institute; Medical Oncology, Melbourne, Victoria
Lkh Salzburg - Univ. Klinikum Salzburg; Iii. Medizinische Abt., Salzburg, Not set
Medizinische Universität Wien; Univ.Klinik für Innere Medizin I - Abt. für Onkologie, Wien, Not set
Oncology Consultants Limited, Nassau, Not set
Cliniques Universitaires St-Luc, Bruxelles, Not set
Clinique Ste-Elisabeth, Namur, Not set
Sint Augustinus Wilrijk, Wilrijk, Not set
University Clinical Centre of the Republic of Srpska, Banja Luka, Not set
Clinic of Oncology, University Clinical Center Sarajevo, Sarajevo, Not set
*X*Instituto Nacional do Cancer - INCA, Rio de Janeiro, RJ
Liga Norte Riograndense Contra O Câncer, Natal, RN
Hospital Nossa Senhora da Conceicao, Porto Alegre, RS
Clinica de Oncologia de Porto Alegre - CliniOnco, Porto Alegre, RS
Hospital Sao Lucas - PUCRS, Porto Alegre, RS
Clinica de Neoplasias Litoral, Itajai, SC
Instituto do Cancer do Estado de Sao Paulo - ICESP, Sao Paulo, SP
Hospital Perola Byington, Sao Paulo, SP
Cross Cancer Institute; Clinical Trials, Edmonton, Alberta
North York General Hospital, Toronto, Ontario
Cuse - Centre Universitaire De Sante; Site Fleurimont, Sherbrooke, Quebec
CHU de Québec ? Hôpital du Saint-Sacrement / ONCOLOGY, Quebec, Not set
Clinica del Country, Bogota, Not set
Instituto Colombiano Para El Avance De La Medicina: Icamedic, Bucaramanga, Not set
Centro Medico Imbanaco, Cali, Not set
Instituto Cancerologico de Nariño, Pasto, Not set
Masarykuv onkologicky ustav, Brno, Not set
Fakultni nemocnice Olomouc; Onkologicka klinika, Olomouc, Not set
Fakultni Poliklinika Vseobecne Fakultni Niemocnice; Onkologicka Klinika, Praha 2, Not set
Fakultni Nemocnice Na Bulovce; Ustav Radiacni Onkologie, Praha, Not set
Vejle Sygehus; Onkologisk Afdeling, Vejle, Not set
HOPITAL JEAN MINJOZ; Oncologie, Besancon, Not set
Centre Jean Perrin; Hopital De Jour, Clermont Ferrand, Not set
Centre Oscar Lambret; Senologie, Lille, Not set
Institut Paoli Calmettes; Oncologie Medicale, Marseille, Not set
Institut régional du Cancer Montpellier, Montpellier, Not set
Centre D'Oncologie de Gentilly; Oncology, Nancy, Not set
Institut Curie; Oncologie Medicale, Paris, Not set
Hopital Saint Louis; Service Onco Thoracique, Paris, Not set
HOPITAL TENON; Cancerologie Medicale, Paris, Not set
Chu La Miletrie; Radiotherapie, Poitiers, Not set
Centre Rene Huguenin; ONCOLOGIE GENETIQUE, Saint Cloud, Not set
Institut de Cancerologie de La Loire; Radiotherapie, St Priest En Jarez, Not set
Klinikum Essen-Mitte Ev. Huyssens-Stiftung / Knappschafts GmbH; Klinik für Senologie / Brustzentrum, Essen, Not set
Universitätsklinikum Halle (Saale); Universitätsklinik Und Poliklinik Für Gynäkologie, Halle, Not set
Facharztzentrum Eppendorf, Studien GbR, Hamburg, Not set
MVZ Onko Medical GmbH Hannover, Ralf Lohse (Geschäftsführer), Hannover, Not set
Nationales Centrum für Tumorerkrankungen (NCT) ; Gyn. Onk. Frauenklinik; Uniklinikum Heidelberg, Heidelberg, Not set
Universitätsklinikum Magdeburg; Frauenheilkunde & Geburtshilfe, Magdeburg, Not set
Universitätsmedizin Mainz; Klinik u. Poliklinik f. Geburtshilfe u. Frauenheilkunde, Mainz, Not set
Mühlenkreiskliniken; Johannes Wesling Klinikum Minden; Klinik für Frauenheilkunde und Geburtshilfe, Minden, Not set
Rotkreuzklinikum München; Frauenklinik, Muenchen, Not set
Klinikum Mutterhaus der Borromaeerinnen gGmbH; Haematologie/Onkologie, Trier, Not set
Alexandras General Hospital of Athens; Oncology Department, Athens, Not set
Univ General Hosp Heraklion; Medical Oncology, Heraklion, Not set
University Hospital of Larissa; Oncology, Larissa, Not set
Grupo Angeles, Guatemala City, Not set
Centro Oncológico Sixtino / Centro Oncológico SA, Guatemala, Not set
Szent Margit Hospital; Dept. of Oncology, Budapest, Not set
Semmelweis Egyetem Onkologiai Központ, Budapest, Not set
Semmelweis Egyetem Aok; Iii.Sz. Belgyogyaszati Klinika, Budapest, Not set
Pécsi Tudományegyetem; Klinikai Központ Onkoterápiás Intézet, Pécs, Not set
Campus Universitario S.Venuta; Centro Oncologico T.Campanella, Catanzaro, Calabria
IRST Istituto Scientifico Romagnolo Per Lo Studio E Cura Dei Tumori, Sede Meldola; Oncologia Medica, Meldola, Emilia-Romagna
A.O. Universitaria Policlinico Di Modena; Ematologia, Modena, Emilia-Romagna
Arcispedale Santa Maria Nuova; Oncologia, Reggio Emilia, Emilia-Romagna
Ospedale Degli Infermi; Divisione Di Oncologia, Rimini, Emilia-Romagna
Azienda Ospedaliero-Universitaria Dipartimento Interaziendale Di Oncologia, Udine, Friuli-Venezia Giulia
Istituto Europeo Di Oncologia, Milano, Lombardia
Fondazione Salvatore Maugeri, Pavia, Lombardia
IRCCS Istituto Clinico Humanitas; Oncologia, Rozzano (MI), Lombardia
Centro Catanese Di Oncologia; Oncologia Medica, Catania, Sicilia
Ospedale Papardo- Piemonte;Oncologia Medica, Messina, Sicilia
Ospedale Misericordia E Dolce; Oncologia Medica, Prato, Toscana
Azienda Ospedaliera Di Perugia Ospedale s. Maria Della Misericordia; Oncologia Medica, Perugia, Umbria
Aichi Cancer Center Hospital, Breast Oncology, Aichi, Not set
Natl Hosp Org Shikoku; Cancer Ctr, Surgery, Ehime, Not set
National Hospital Organization Kyushu Cancer Center;Breast Oncology, Fukuoka, Not set
Gifu University Hospital; Digestive Surgery, Gifu, Not set
Hiroshima University Hospital; Breast Surgery, Hiroshima, Not set
National Hospital Organization Hokkaido Cancer Center; Breast Surgery, Hokkaido, Not set
Hyogo College Of Medicine; Breast And Endocrine Surgery, Hyogo, Not set
Hyogo Cancer Center; Breast Surgery, Hyogo, Not set
Kanazawa University Hospital; Breast Oncology, Ishikawa, Not set
Iwate Med Univ School of Med; Surgery, Iwate, Not set
Sagara Hospital; Breast Surgery, Kagoshima, Not set
Tokai University Hospital, Breast Surgery, Kanagawa, Not set
Kumamoto University Hospital; Breast and Endocrine Surgery, Kumamoto, Not set
Kumamoto City Hospital, Breast and Endocrine Surgery, Kumamoto, Not set
Kyoto University Hospital; Breast Surgery, Kyoto, Not set
Tohoku University Hospital; General Surgery, Miyagi, Not set
Niigata Cancer Ctr Hospital; Breast Surgery, Niigata, Not set
Kawasaki Medical School Hospital; Breast and Thyroid Surgery, Okayama, Not set
National Hospital Organization Osaka National Hospital; Breast Surgery, Osaka, Not set
Osaka University Hospital; Breast and Endocrine Surgery, Osaka, Not set
Saitama Medical University International Medical Center; Medical Oncology, Saitama, Not set
Saitama Cancer Center, Breast Oncology, Saitama, Not set
Shizuoka Cancer Center; Breast Surgery, Shizuoka, Not set
Shizuoka General Hospital; Breast Surgery, Shizuoka, Not set
National Cancer Center Hospital; Medical Oncology, Tokyo, Not set
Toranomon Hospital; Breast and Endocrine Surgery, Tokyo, Not set
The Cancer Inst. Hosp. of JFCR; Breast Oncology Center, Tokyo, Not set
Tokyo Medical Uni. Hospital; Breast Oncology, Tokyo, Not set
Seoul National University Bundang Hospital; Hematology Medical Oncology, Gyeonggi-do, Not set
Seoul National Uni Hospital; Dept. of Internal Medicine/Hematology/Oncology, Seoul, Not set
Samsung Medical Centre; Division of Hematology/Oncology, Seoul, Not set
Asan Medical Center, Uni Ulsan Collegemedicine; Dept.Internal Medicine / Divisionhematology/Oncology, Seoul, Not set
Korea University Guro Hospital; Oncology, Seoul, Not set
Pantai Hospital Kuala Lumpur; Dept of Oncology & Radiotherapy, Kuala Lumpur, FED. Territory OF Kuala Lumpur
Beacon International Specialist Centre, Petaling Jaya, Selangor, Selangor
Sunway Medical Centre, Selangor, Not set
Centro de Investigacion; Clinica Del Pacifico, Acapulco, Guerrero
Centro Universitario Contra El Cancer, Monterrey, Nuevo LEON
Oaxaca Site Management Organization, Oaxaca de Juárez, Oaxaca
Hospital Privado San Jose; Oncologia, Obregon, Sonora
Centenario Hospital Miguel Hidalgo, Aguascalientes, Not set
Centro Oncológico Estatal; ISSSEMYM Oncología, Toluca, Not set
Auckland city hospital; Auckland Regional Cancer Centre and Blood Service, Auckland, Not set
Waikato Hospital; Regional Cancer Center, Hamilton, Not set
Private Health Organization Acibadem Sistina Hospital, Skopje, Not set
The Panama Clinic, Panama, Not set
Hospital Nacional Carlos Alberto Seguin Escobedo-Essalud; Oncology & Haemathology, Arequipa, Not set
Hospital Nacional Edgardo Rebagliati Martins; Oncologia, Lima, Not set
Unidad de Investigacion Oncologia Clinica ? Piura; Unidad de Oncología Clínica, Piura, Not set
Cebu Cancer Institute; Perpetual Succour Hospital, Cebu City, Not set
Cardinal Santos Medical Center, San Juan, Not set
Centrum Onkologii;Im. Franciszka Lukaszczyka;Onkologii, Bydgoszcz, Not set
Medical University of Gdansk, Gdansk, Not set
Centrum Onkologii, Instytut, Klinika Chemioterapii; Oddzial Chemoterapii, Krakow, Not set
COZL Oddzial Onkologii Klinicznej z pododdzialem Chemioterapii Dziennej, Lublin, Not set
Cent.Onkologii-Instytut im. M. S-Curie, Klinika Now. Piersi i Chirurgii Rekon, Warszawa, Not set
IPO do Porto; Servico de Oncologia Medica, Porto, Not set
Coltea Hospital; Oncology, Bucharest, Not set
Prof. Dr. I. Chiricuta Institute of Oncology, Cluj Napoca, Not set
Cluj Clinical County Hospital; Oncology Dept, Cluj-Napoca, Not set
Moscow city oncology hospital; #62 of Moscow Healthcare Department, Moscow, Moskovskaja Oblast
Blokhin Cancer Research Center; Combined Treatment, Moskva, Moskovskaja Oblast
Ryazan State Medical University Named after I.P.Pavlov, Ryazan, Rjazan
State Budget Institution of Healthcare of Stavropol region Pyatigorsk Oncology Dispensary, Pyatigorsk, Stavropol
Clinical Oncology Dispensary of Ministry of Health of Tatarstan, Kazan, Tatarstan
Ivanovo Regional Oncology Dispensary, Ivanovo, Not set
SBI of Healthcare Samara Regional Clinical Oncology Dispensary, Samara, Not set
SBI of Healthcare of Stavropol region Stavropol Regional Clinical Oncology Dispensary, Stavropol, Not set
Tula Regional Oncology Dispensary, Tula, Not set
GUZ Vladimir Regional Clinical Oncological Dispensary, Vladimir, Not set
Hospital General Universitario de Elche; Servicio de Oncologia, Elche, Alicante
Hospital Univ Vall d'Hebron; Servicio de Oncologia, Sant Andreu de La Barca, Barcelona
Complejo Hospitalario Universitario de Santiago (CHUS) ; Servicio de Oncologia, Santiago de Compostela, LA Coruña
Hospital del Mar; Servicio de Oncologia, Barcelona, Not set
Complejo Hospitalario de Jaen-Hospital Universitario Medico Quirurgico; Servicio de Oncologia, Jaen, Not set
Complejo Hospitalario Universitario A Coruña (CHUAC, Materno Infantil), Oncología, La Coruña, Not set
Hospital General Universitario Gregorio Marañon; Servicio de Oncologia, Madrid, Not set
Hospital Universitario 12 de Octubre; Servicio de Oncologia, Madrid, Not set
Hospital Universitario La Paz; Servicio de Oncologia, Madrid, Not set
Hospital Clinico Universitario Virgen de la Victoria; Servicio de Oncologia, Malaga, Not set
Hospital Clinico Universitario de Valencia; Servicio de Onco-hematologia, Valencia, Not set
Skånes Universitetssjukhus; Kliniska Forskningsenheten Onkologimottagning medicinsk behandling, Malmö, Not set
Kantonsspital Baden; Medizinische Klinik, Onkologie, Baden, Not set
Universitaetsspital Basel; Onkologie, Basel, Not set
Kantonsspital Graubünden Medizin Onkologie; Onkologie und Hämatologie, Chur, Not set
Changhua Christian Hospital; Hematology-Oncology, Changhua, Not set
Kaohsiung Medical Uni Chung-Ho Hospital; Dept of Surgery, Kaohsiung, Not set
National Taiwan Uni Hospital; Dept of Oncology, Taipei, Not set
Tri-Service General Hospital; Hematology and Oncology, Taipei, Not set
National Cancer Inst., Bangkok, Not set
Rajavithi Hospital; Division of Medical Oncology, Bangkok, Not set
Ramathibodi Hospital; Dept of Med.-Div. of Med. Onc, Bangkok, Not set
Faculty of Med. Siriraj Hosp.; Med.-Div. of Med. Oncology, Bangkok, Not set
Maharaj Nakorn Hospital; Internal Medicine, Chiang Mai, Not set
Songklanagarind Hospital; Department of Oncology, Songkhla, Not set
Baskent University Adana Dr. Turgut Noyan Practice and Research Hospital; Medical Oncology, Adana, Not set
Cukurova Uni Faculty of Medicine; Medical Oncology, Adana, Not set
Gazi Uni Medical Faculty Hospital; Oncology Dept, Ankara, Not set
Ege Uni Medical Faculty Hospital; Oncology Dept, Izmir, Not set
Bristol Haematology and Oncology centre, Bristol, Not set
Cambridge University Hospitals NHS Foundation Trust, Cambridge, Not set
Royal Cornwall Hospital; Dept of Clinical Oncology, Cornwall, Not set
The Beatson West of Scotland Cancer Centre; Cancer Clinical Trials Unit, Glasgow, Not set
Leicester Royal Infirmary; Dept. of Medical Oncology, Leicester, Not set
Royal Free Hospital; Dept of Oncology, London, Not set
Guys Hospital; Management Offices, London, Not set
Royal Marsden Hospital; Dept of Med-Onc, London, Not set
Christie Hospital; Breast Cancer Research Office, Manchester, Not set
Nottingham City Hospital; Oncology, Nottingham, Not set
Peterborough City Hospital; Oncology Ward, Peterborough, Not set
Queen Alexandra Hospital, Portsmouth, Portsmouth, Not set
Weston Park Hospital; Cancer Clinical Trials Centre, Sheffield, Not set
Southampton General Hospital; Somers Cancer Research Building, Southampton, Not set
Uni Hospital of North Staffordshire; Staffordshire Oncology Centre, Stoke-on-Trent, Not set
Royal Marsden Hospital; Dept of Medical Oncology, Sutton, Not set
Conditions: Breast Cancer
A Study of Ipatasertib in Combination With Atezolizumab and Paclitaxel as a Treatment for Participants With Locally Advanced or Metastatic Triple-Negative Breast Cancer
Completed
This study evaluated the efficacy and safety of ipatasertib in combination with atezolizumab and paclitaxel in locally advanced or metastatic Triple-Negative Breast Cancer (TNBC) previously untreated in this setting.
This study evaluated the efficacy and safety of ipatasertib in combination with atezolizumab and paclitaxel in locally advanced or metastatic Triple-Negative Breast Cancer (TNBC) previously untreated in this setting. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/26/2024
Locations: USA Mitchell Cancer Institute, Mobile, Alabama +181 locations
USA Mitchell Cancer Institute, Mobile, Alabama
Highlands Oncology Group, Springdale, Arkansas
UCLA, Los Angeles, California
Kaiser Permanente-SCPMG; Oncology Research, San Diego, California
Stanford Cancer Center, Stanford, California
Kaiser Permanente - Franklin, Denver, Colorado
Stamford Hospital; BCC, MOHR, Stamford, Connecticut
Holy Cross Hospital, Fort Lauderdale, Florida
Memorial Healthcare System - Memorial Regional Hospital, Hollywood, Florida
Memorial Cancer Institute at Memorial West, Pembroke Pines, Florida
Winship Cancer Institute, Atlanta, Georgia
Nancy N. and J.C. Lewis Cancer & Research Pavillion -St. Josephs / Candler Health System-CCD PRIME, Savannah, Georgia
Rush University, Chicago, Illinois
Ochsner Clinic Foundation, Baton Rouge, Louisiana
Ochsner Health System, New Orleans, Louisiana
University of Maryland Medical Center, Baltimore, Maryland
Mercy Medical Center, Baltimore, Maryland
Medstar Franklin Square Medical Center, Baltimore, Maryland
St. Joseph Mercy Hospital; Cancer Care Center., Ann Arbor, Michigan
Henry Ford Health System, Detroit, Michigan
Jackson Oncology Associates, PLLC, Jackson, Mississippi
CHI Health Saint Francis; Oncology, Grand Island, Nebraska
Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire
Hackensack Univ Med Ctr, Hackensack, New Jersey
Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina
Kaiser Permanente - Portland, Portland, Oregon
Oregon Health and Science University, Portland, Oregon
Charleston Oncology, P .A, Charleston, South Carolina
Greenville Health System; Cancer Center, Greenville, South Carolina
The West Clinic; West Cancer Center, Germantown, Tennessee
Vanderbilt Univ Medical Ctr, Nashville, Tennessee
Fundación CENIT para la Investigación en Neurociencias, Buenos Aires, Not set
Inst. Angel Roffo; Haematology, Buenos Aires, Not set
Hospital Britanico, Ciudad Autonoma Bs As, Not set
Instituto Medico Rio Cuarto, Cordoba, Not set
Centro Oncologico Riojano Integral (CORI), La Rioja, Not set
Fundacion Scherbovsky, Mendoza, Not set
Macquarie University Hospital, Macquarie Park, New South Wales
Mid North Coast Cancer Institute, Port Macquarie, New South Wales
Royal North Shore Hospital; Department of Medical Oncology, St Leonards, New South Wales
Calvary Mater Newcastle; Medical Oncology, Waratah, New South Wales
Princess Alexandra Hospital, Woolloongabba, Queensland
Adelaide Cancer Centre, Kurralta Park, South Australia
Monash Health Monash Medical Centre, Clayton, Victoria
Peter MacCallum Cancer Centre; Medical Oncology, Melbourne, Victoria
Sunshine Hospital; Oncology Research, St Albans, Victoria
St John of God Hospital; Bendat Cancer Centre, Subiaco, Western Australia
Tiroler Landeskrankenanstalten Ges.M.B.H.; Abt. Für Gynäkologie, Innsbruck, Not set
Ordensklinikum Linz Barmherzige Schwestern; Interne 1 - Hämato-Onkologie, Linz, Not set
Uniklinikum Salzburg, LKH; Univ.Klinik f. Innere Medizin III der PMU, Salzburg, Not set
Medizinische Universität Wien; Univ.Klinik für Innere Medizin I, Wien, Not set
AZ Maria Middelares, Gent, Not set
Jessa Zkh (Campus Virga Jesse), Hasselt, Not set
Hospital Sao Rafael - HSR, Salvador, BA
Hospital das Clinicas - UFRGS, Porto Alegre, RS
Clinica de Pesquisa e Centro de Estudos em Oncologia Ginecologica e Mamaria Ltda, Sao Paulo, SP
Núcleo de Pesquisa São Camilo; ONCOLOGIA CLINICA / QUIMIOTERAPIA, Sao Paulo, SP
MHAT Nadezhda, Sofia, Not set
Cross Cancer Institute ; Dept of Medical Oncology, Edmonton, Alberta
Fraser Valley Centre British Columbia Cancer Agency, Surrey, British Columbia
Cancer Care Manitoba, Winnipeg, Manitoba
Royal Victoria Hospital, Barrie, Ontario
The Ottawa Hospital Cancer Centre, Ottawa, Ontario
McGill University; Glen Site; Oncology, Montreal, Quebec
Jewish General Hospital; Research Unit, Montréal, Quebec
Hopital du Saint Sacrement, Quebec City, Quebec
Clinica del Country, Bogota, Not set
Oncólogos de Occidente, Pereira, Not set
Clinica CIMCA, San José, Not set
Masaryk?v onkologický ústav; Klinika komplexní onkologické pé?e, Brno, Not set
Fakultni nemocnice Olomouc; Onkologicka klinika, Olomouc, Not set
Herlev Hospital; Afdeling for Kræftbehandling, Herlev, Not set
Odense Universitetshospital, Onkologisk Afdeling R, Odense C, Not set
Docrates Cance Center, Helsinki, Not set
KYS Sadesairaala; Syopatautien poliklinikka, Kuopio, Not set
VAASAN KESKUSSAIRAALA; Onkologian poliklinikka, Vaasa, Not set
Centre Eugene Marquis; Service d'oncologie, Rennes, Not set
Agioi Anargyroi Cancer Hospital; 2Nd Oncology Dept., Kifisia, Not set
Euromedical General Clinic of Thessaloniki; Oncology Department, Thessaloniki, Not set
Queen Mary Hospital; Dept of Medicine, Hong Kong, Not set
Tuen Mun Hospital; Clinical Onc, Hong Kong, Not set
Prince of Wales Hospital; Department of Clinical Onocology, Shatin, Not set
Sahyadri Super Specialty Hospital Hadapsar, Pune, Maharashtra
Shaare Zedek Medical Center, Jerusalem, Not set
Istituto Nazionale per lo Studio e la Cura dei Tumori Fondazione G. Pascale, Napoli, Campania
IRST Istituto Scientifico Romagnolo Per Lo Studio E Cura Dei Tumori, Sede Meldola; Oncologia Medica, Meldola, Emilia-Romagna
ASU FC S. M. DELLA MISERICORDIA; Oncologia, Udine, Friuli-Venezia Giulia
ASST DEGLI SPEDALI CIVILI DI BRESCIA; Oncologia Medica, Brescia, Lombardia
ASST DI LECCO; Oncologia Medica, Lecco, Lombardia
IRCCS Istituto Clinico Humanitas; Oncologia, Rozzano (MI), Lombardia
Ospedale Civile; Unita Operativa Di Oncologia Medica, Livorno, Toscana
IOV - Istituto Oncologico Veneto - IRCCS; Oncologia Medica II, Padova, Veneto
Aichi Cancer Center Hospital, Aichi, Not set
Fukushima Medical University Hospital, Fukushima, Not set
Gunma Prefectural Cancer Center, Gunma, Not set
Hiroshima University Hospital, Hiroshima, Not set
Kanagawa Cancer Center, Kanagawa, Not set
Kumamoto Shinto General Hospital, Kumamoto, Not set
Okayama University Hospital, Okayama, Not set
Osaka International Cancer Institute, Osaka, Not set
Kyungpook National University Medical Center, Daegu, Not set
National Cancer Center, Goyang-si, Not set
Severance Hospital, Yonsei University Health System, Seoul, Not set
Asan Medical Center, Seoul, Not set
Samsung Medical Center, Seoul, Not set
Seoul St Mary's Hospital, Seoul, Not set
Investigacion Oncofarmaceutica, La Paz, BAJA California SUR
Health Pharma Professional Research, Cdmx, Mexico CITY (federal District)
Christus Muguerza Clinica Vidriera, Monterrey, Nuevo LEON
Auckland City Hospital, Cancer and Blood Research, Auckland, Not set
Tauranga Hospital, Clinical Trials Unit; BOP Clinical School, Tauranga, Not set
Wellington Regional Hospital; Clinical Trials Unit, Wellington, Not set
Centro Medico Monte Carmelo, Arequipa, Not set
Instituto Regional de Enfermedades Neoplasicas, Arequipa, Not set
Unidad de Investigación Oncologica; Hospital Nacional Daniel Alcides Carrion, Lima, Not set
Clínica San Gabriel; Unidad de Investigación Oncológica de la Clínica San Gabriel, Lima, Not set
Hospital Arzobispo Loayza, Lima, Not set
Oncosalud Sac; Oncología, Lima, Not set
Instituto Nacional de Enfermedades Neoplasicas, Lima, Not set
Clinica Ricardo Palma, San Isidro, Not set
Instyt. Centrum Zdrowia Matki Polki; Klinika Chirurgii Onk. Chorób Piersi z Podod. Onko Klinicznej, ?ód?, Not set
Narodowy Inst.Onkol.im.Sklodowskiej-Curie Panstw.Inst.Bad Gliwice; Centr.Diagn.i Lecz.Chor.Piersi, Gliwice, Not set
Szpital Uniwersytecki w Krakowie, Oddzia? Kliniczny Kliniki Onkologii, Kraków, Not set
Wielkopolskie Centrum Onkologii, Poznan, Not set
Narodowy Instytut Onkologii im. M.Sklodowskiej-Curie; Klinika Nowotworow Piersi i Chirurgii Rekonstr, Warszawa, Not set
Hospital da Luz; Departamento de Oncologia Medica, Lisboa, Not set
Hospital de Santa Maria; Servico de Oncologia Medica, Lisboa, Not set
Hospital Beatriz Angelo; Departamento de Oncologia, Loures, Not set
Centro Hospitalar do Porto ? Hospital de Santo António; Oncologia, Porto, Not set
IPO do Porto; Servico de Oncologia Medica, Porto, Not set
Oncology Center Sf. Nectarie, Craiova, Not set
Arkhangelsk Regional Clinical Oncology Dispensary, Arkhangelsk, Arhangelsk
University ?linic of headaches, Moscow, Moskovskaja Oblast
P.A. Gertsen Cancer Research Inst. ; Chemotherapy Dept, Moscow, Moskovskaja Oblast
SBIH "Moscow Clinical Scientific and Practical Center named after A.S. Loginov of DHM", Moskva, Moskovskaja Oblast
Fed State Budgetary Inst "N.N. Blokhin Med Center of Oncology" MHRF, Moskva, Moskovskaja Oblast
FSAI Treatment and rehabilitation Centre Ministry of Health; Clinical research and chemotherapy., Moskva, Moskovskaja Oblast
S-Pb clinical scientific practical center of specialized kinds of medical care (oncological), Saint-Petersburg, Sankt Petersburg
Clinical Oncology Dispensary of Ministry of Health of Tatarstan, Kazan, Tatarstan
Limited Liability Company "RC Medical", Novosibirsk, Not set
National Cancer Centre; Medical Oncology, Singapore, Not set
National Hospital; Oncotherapy Dept, Bloemfontein, Not set
Cancercare, George, Not set
Wits Clinical Research, Johannesberg, Not set
Cancercare, Port Elizabeth, Not set
Wilgers Oncology Centre, Pretoria, Not set
Hospital Univ Vall d'Hebron; Servicio de Oncologia, Sant Andreu de La Barca, Barcelona
Hospital Provincial de Castellon; Servicio de Oncologia, Castellon de La Plana, Castellon
Complejo Hospitalario Universitario A Coruña (CHUAC); Servicio de Oncologia, A Coruña, LA Coruña
Hospital Universitario Puerta de Hierro; Servicio de Oncologia, Majadahonda, Madrid
Hospital Clínic i Provincial; Servicio de Hematología y Oncología, Barcelona, Not set
Hospital General Universitario Gregorio Marañon; Servicio de Oncologia, Madrid, Not set
Hospital Ramon y Cajal; Servicio de Oncologia, Madrid, Not set
Hospital Universitario Clínico San Carlos; Servicio de Oncologia, Madrid, Not set
Centro Integral Oncologico Clara Campal; Servicio de Oncología, Madrid, Not set
Hospital Clinico Universitario Virgen de la Victoria; Servicio de Oncologia, Malaga, Not set
Hospital Clínico Universitario de Valencia; Servicio de Oncología, Valencia, Not set
Universitätsspital Basel, Basel, Not set
Universitätsspital Zürich Gynäkologische Klinik; Klinik für Gynäkologie, Zürich, Not set
China Medical University Hospital; Surgery, Taichung, Not set
VETERANS GENERAL HOSPITAL; Department of General Surgery, Taipei, Not set
National Taiwan Uni Hospital; General Surgery, Taipei, Not set
Chang Gung Memorial Hosipital at Linkou, Taoyuan City, Not set
Chulalongkorn Hospital; Medical Oncology, Bangkok, Not set
Rajavithi Hospital; Division of Medical Oncology, Bangkok, Not set
Faculty of Med. Siriraj Hosp.; Med.-Div. of Med. Oncology, Bangkok, Not set
Maharaj Nakorn Chiang Mai Hospital; Department of Surgery/Head Neck and Breast Unit; Clinical Trial, Chiang Mai, Not set
Khonkaen Hospital, Khonkaen, Not set
Songklanagarind Hospital; Department of Oncology, Songkhla, Not set
Memorial Ankara Hastanesi, Ankara, Not set
Medipol University Medical Faculty; Oncology Department, Istanbul, Not set
Hacettepe Uni Medical Faculty Hospital; Oncology Dept, Sihhiye/Ankara, Not set
SI Institute of general&urgent surgery n/a Zaytseva V.T NAMSU; Purulent Surgery department, Kharkiv, Kharkiv Governorate
Regional Oncology Center; Department of Mammology, Chernigiv, Not set
Chemotherapy SI Dnipropetrovsk MA of MOHU, Dnipropetrovsk, Not set
ME Kryviy Rih Oncology Dispensary of Dnipropetrovs?k Regional Council; Chemotherapy Department, Kryvyi Rih, Not set
MI Kyiv Regional Council Kyiv Regional Oncological Dispensary; Department of Mammology, Kyiv, Not set
Municipal Institution Odesa Regional Clinical Hospital, Odesa, Not set
RCI Sumy Regional Clinical Oncological Dispensary, Sumy, Not set
BEATSON WEST OF SCOTLAND CANCER CENTRE; Clinical Research Unit ? Level 1, Glasgow, Not set
The Royal Marsden Hospital, Fulham, London, Not set
Nottingham University Hospitals NHS Trust, Nottingham, Not set
Conditions: Triple-Negative Breast Cancer
A Study of Ipatasertib in Combination With Paclitaxel as a Treatment for Participants With PIK3CA/AKT1/PTEN-Altered, Locally Advanced or Metastatic, Triple-Negative Breast Cancer or Hormone Receptor-Positive, HER2-Negative Breast Cancer
Completed
This study will evaluate the efficacy of ipatasertib + paclitaxel versus placebo + paclitaxel in participants with histologically confirmed, locally advanced or metastatic triple-negative breast cancer (TNBC) and in participants with locally advanced or metastatic hormone receptor positive (HR+)/ human epidermal growth factor receptor 2 negative (HER2-) breast adenocarcinoma who are not suitable for endocrine therapy.
This study will evaluate the efficacy of ipatasertib + paclitaxel versus placebo + paclitaxel in participants with histologically confirmed, locally advanced or metastatic triple-negative breast cancer (TNBC) and in participants with locally advanced or metastatic hormone receptor positive (HR+)/ human epidermal growth factor receptor 2 negative (HER2-) breast adenocarcinoma who are not suitable for endocrine therapy. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/15/2024
Locations: UCSD Moores Cancer Center, La Jolla, California +175 locations
UCSD Moores Cancer Center, La Jolla, California
USC Norris Cancer Center, Los Angeles, California
USC Norris Cancer Center; USC Oncology Hematology Newport Beach, Newport Beach, California
Kaiser Permanente - Oakland, Oakland, California
Kaiser Permanente - Roseville, Roseville, California
UC Davis; Comprehensive Cancer Center, Sacramento, California
Kaiser Permanente Sacramento Medical Center, Sacramento, California
Kaiser Permanente - San Francisco (2238 Geary), San Francisco, California
UCSF Comprehensive Cancer Ctr, San Francisco, California
K. Permanente - San Jose, San Jose, California
Kaiser Permanente - San Leandro, San Leandro, California
K. Permanente - Santa Clara, Santa Clara, California
Kaiser Permanente - South San Francisco, South San Francisco, California
Kaiser Permanente - Vallejo, Vallejo, California
K. Permanente - Walnut Creek, Walnut Creek, California
Memorial Regional Hospital, Hollywood, Florida
Mount Sinai Comprehensive Cancer Center, Miami Beach, Florida
UF Health Cancer Center at Orlando Health, Orlando, Florida
Memorial Hospital West, Pembroke Pines, Florida
University of Maryland, Baltimore, Maryland
Mercy Medical Center, Baltimore, Maryland
Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland
Memorial Sloan Kettering Cancer Center at Westchester, Harrison, New York
Memorial Sloan Kettering, New York, New York
West Clinic, Germantown, Tennessee
Texas Oncology, P.A., Dallas, Texas
UT Southwestern Medical Center; Simmons Comprehensive Cancer Center, Simmons Pharmacy, Dallas, Texas
Oncology Consultants PA, Houston, Texas
Fundación CENIT para la Investigación en Neurociencias, Buenos Aires, Not set
Hosp Provincial D. Centenarios; Oncology Dept, Rosario, Not set
Chris O'Brien Lifehouse, Camperdown, New South Wales
Calvary Mater Newcastle; Medical Oncology, Waratah, New South Wales
Westmead Hospital; Medical Oncology, Wentworthville, New South Wales
Mater Hospital; Cancer Services, South Brisbane, Queensland
Cabrini Medical Centre; Oncology, Malvern, Victoria
Fiona Stanley Hospital; FSH Cancer Centre Clinical Trials Unit, Bull Creek, Western Australia
Cliniques Universitaires St-Luc, Bruxelles, Not set
GHdC Site Notre Dame, Charleroi, Not set
UZ Leuven Gasthuisberg, Leuven, Not set
Santa Casa de Misericordia de Salvador, Salvador, BA
Hospital Araujo Jorge; Departamento de Ginecologia E Mama, Goiania, GO
Hospital do Câncer de Londrina, Londrina, PR
Instituto Nacional de Cancer - INCa; Oncologia, Rio de Janeiro, RJ
Hospital Sao Lucas - PUCRS, Porto Alegre, RS
Hospital Nossa Senhora da Conceicao, Porto Alegre, RS
Faculdade de Medicina do ABC - FMABC, Santo Andre, SP
Hospital Perola Byington, Sao Paulo, SP
British Columbia Cancer Agency (Bcca) - Vancouver Cancer Centre, Vancouver, British Columbia
Jewish General Hospital, Montreal, Quebec
Sociedad de Investigaciones Medicas Ltda (SIM), Temuco, Not set
Clinica CIMCA, San José, Not set
ICIMED Instituto de Investigación en Ciencias Médicas, San José, Not set
Masaryk?v onkologický ústav; Klinika komplexní onkologické pé?e, Brno, Not set
Fakultni nemocnice Olomouc; Onkologicka klinika, Olomouc, Not set
CHU Besançon - Hôpital Jean Minjoz, Besançon Cedex, Not set
Polyclinique Bordeaux Nord Aquitaine, Bordeaux, Not set
Centre Georges Francois Leclerc; Oncologie 3, Dijon, Not set
ICM; Medecine B3, Montpellier cedex 5, Not set
Centre Catherine De Sienne, Nantes, Not set
APHP - Hospital Saint Louis, Paris, Not set
Institut Jean Godinot; Oncologie Medicale, Reims CEDEX, Not set
Onkologische Schwerpunktpraxis Kurfürstendamm, Berlin, Not set
Praxis für Interdisziplinäre Onkologie und Hämatologie GbR, Freiburg, Not set
Universitätsklinikum Hamburg-Eppendorf; Frauenklinik, Hamburg, Not set
Universitätsklinikum des Saarlandes; Klinik f. Frauenheilkunden und Geburtshilfe, Homburg/Saar, Not set
Praxis Dr.med. Katja Ziegler-Löhr, Köln, Not set
Dres. Andreas Köhler und Roswitha Fuchs, Langen, Not set
Mühlenkreiskliniken; Johannes Wesling Klinikum Minden; Klinik für Frauenheilkunde und Geburtshilfe, Minden, Not set
Oncologianova GmbH - Gesellschaft für Innovationen in der Onkologie, Recklinghausen, Not set
Universitätsfrauen- und Poliklinik am Klinikum Suedstadt, Rostock, Not set
Universitätsklinikum Würzburg; Frauenklinik, Würzburg, Not set
Anticancer Hospital Ag Savas; 1St Dept of Internal Medicine, Athens, Not set
Agioi Anargyroi; 3Rd Dept. of Medical Oncology, Athens, Not set
Euromedical General Clinic of Thessaloniki; Oncology Department, Thessaloniki, Not set
Orszagos Onkologial Intezet; Onkologiai Osztaly X, Budapest, Not set
Borsod-Abauj-Zemplen Megyei Korhaz Es Egyetemi Oktato Korhaz; Onkologiai Osztaly, Miskolc, Not set
Szegedi Tudomanyegyetem, AOK, Szent-Gyorgyi Albert Klinikai Kozpont, Onkoterapias Klinika, Szeged, Not set
Hetenyi Geza County Hospital; Onkologiai Kozpont, Szolnok, Not set
Zala County Hospital ICU, Zalaegerszeg, Not set
Indraprastha Apollo Hospitals, New Delhi, Delhi
Rajiv Gandhi Cancer Inst.&Research Center; Medical Oncology, New Delhi, Delhi
Istituto Nazionale Tumori Irccs Fondazione g. PASCALE;U.O.C. Oncologia Medica Senologica, Napoli, Campania
Azienda Ospedaliero-Universitaria S.Orsola-Malpighi; Unità Operativa Oncologia Medica, Bologna, Emilia-Romagna
Irccs Centro Di Riferimento Oncologico (CRO); Dipartimento Di Oncologia Medica, Aviano, Friuli-Venezia Giulia
Ospedale Santa Maria Annunziata; Oncologia, Bagno a Ripoli, Toscana
IOV - Istituto Oncologico Veneto - IRCCS; Oncologia Medica II, Padova, Veneto
Aichi Cancer Center Hospital, Aichi, Not set
National Cancer Center Hospital East, Chiba, Not set
National Hospital Organization Kyushu Cancer Center;Breast Oncology, Fukuoka, Not set
Fukushima Medical University Hospital, Fukushima, Not set
Hyogo Medical University Hospital, Hyogo, Not set
St. Marianna University Hospital, Kanagawa, Not set
Kanagawa Cancer Center, Kanagawa, Not set
Tokai University Hospital, Kanagawa, Not set
Kumamoto Shinto General Hospital, Kumamoto, Not set
Niigata Cancer Center Hospital, Niigata, Not set
Okayama University Hospital, Okayama, Not set
National Hospital Organization Osaka National Hospital, Osaka, Not set
Kinki University Hospital, Faculty of Medicine; Surgery, Osaka, Not set
Saitama Cancer Center, Breast Oncology, Saitama, Not set
Shizuoka Cancer Center, Shizuoka, Not set
National Cancer Center Hospital, Tokyo, Not set
St. Luke's International Hospital, Tokyo, Not set
The Cancer Institute Hospital of JFCR, Tokyo, Not set
Showa University Hospital; Breast Surgery, Tokyo, Not set
National Cancer Center, Goyang-si, Not set
Inha University Hospital, Incheon, Not set
Seoul National University Bundang Hospital, Seongnam-si, Not set
Seoul National University Hospital, Seoul, Not set
Severance Hospital, Yonsei University Health System, Seoul, Not set
Asan Medical Center, Seoul, Not set
Samsung Medical Center, Seoul, Not set
Centro Medico Dalinde, Cdmx, Mexico CITY (federal District)
Centro Médico Zambrano Hellion, Monterrey, Nuevo LEON
Merida | Investigacion Clinica, Mérida, Yucatan
CENEIT Oncologicos; DENTRO DE CONDOMINIO SAN FRANCISCO, Mexico City, Not set
Clinical Hospital; Oncology Department, Bitola, Not set
PHI University Clinic of Radiotherapy and Oncology; Breast malignancy, Skopje, Not set
PHI University Clinic of Radiotherapy and Oncology; Malignant diseases of thorax, Skopje, Not set
Centro Medico Monte Carmelo, Arequipa, Not set
Hospital Daniel Alcides Carrion, Callao, Not set
Clínica San Gabriel; Unidad de Investigación Oncológica de la Clínica San Gabriel, Lima, Not set
Hospital Nacional Cayetano Heredia; Ocología; Servicio de Hematología Oncología Médica, Lima, Not set
Oncosalud Sac; Oncología, Lima, Not set
Instituto Nacional de Enfermedades Neoplasicas, Lima, Not set
Clinica Ricardo Palma, San Isidro, Not set
Instituto Regional de Enfermedades Neoplasicas - IREN Norte, Trujillo, Not set
Instyt. Centrum Zdrowia Matki Polki; Klinika Chirurgii Onk. Chorób Piersi z Podod. Onko Klinicznej, ?ód?, Not set
Narodowy Inst.Onkol.im.Sklodowskiej-Curie Panstw.Inst.Bad Gliwice; III Klin. Radioter. i Chemioter., Gliwice, Not set
Narodowy Instytut Onkologii im. M.Sklodowskiej-Curie; Klinika Nowotworow Piersi i Chirurgii Rekonstr, Warszawa, Not set
Arkhangelsk Regional Clinical Oncology Dispensary, Arkhangelsk, Arhangelsk
Moscow City Oncology Hospital #62, Moscovskaya Oblast, Moskovskaja Oblast
Federal State Institution, Moscow Research Oncology Institute n.a. P.A. Hertzen; Oncourology, Moscow, Moskovskaja Oblast
Blokhin Cancer Research Center; Combined Treatment, Moskva, Moskovskaja Oblast
FSI Rostov research oncological institute of MoH and SD of RF; PAD, Rostov-on-Don, Rostov
S-Pb clinical scientific practical center of specialized kinds of medical care (oncological), Saint-Petersburg, Sankt Petersburg
Clinical Oncology Dispensary of Ministry of Health of Tatarstan, Kazan, Tatarstan
Ivanovo Regional Oncology Dispensary, Ivanovo, Not set
SBIH Kaluga Region Clinical Oncology Dispensary, Kaluga, Not set
National University Hospital; National University Cancer Institute, Singapore (NCIS), Singapore, Not set
National Cancer Centre; Medical Oncology, Singapore, Not set
Institute of Oncology Ljubljana, Ljubljana, Not set
Medical Oncology Centre of Rosebank; Oncology, Johannesburg, Not set
Hospital Provincial de Castellon; Servicio de Oncologia, Castellon de La Plana, Castellon
Hospital Universitario Reina Sofia; Servicio de Oncologia, Córdoba, Cordoba
Complejo Hospitalario Universitario de Santiago (CHUS) ; Servicio de Oncologia, Santiago de Compostela, LA Coruña
Hospital Universitario Puerta de Hierro; Servicio de Oncologia, Majadahonda, Madrid
Hospital del Mar; Servicio de Oncologia, Barcelona, Not set
Vall d?Hebron Institute of Oncology (VHIO), Barcelona, Barcelona, Not set
Hospital Clinic Barcelona; Servicio de oncologia, Barcelona, Not set
Hospital de Donostia; Servicio de Oncologia, Guipuzcoa, Not set
Hospital Ramon y Cajal; Servicio de Oncologia, Madrid, Not set
HOSPITAL DE MADRID NORTE SANCHINARRO- CENTRO INTEGRAL ONCOLOGICO CLARA CAMPAL; Servicio de Oncologia, Madrid, Not set
Hospital Universitario Virgen del Rocio; Servicio de Oncologia, Sevilla, Not set
Hospital Clinico Universitario; Oncologia, Valencia, Not set
Chi Mei Medical Center Liou Ying Campus, Liuying Township, Not set
Koo Foundation Sun Yat-Sen Cancer Center; Hemato-Oncology, Taipei City, Not set
VETERANS GENERAL HOSPITAL; Department of General Surgery, Taipei, Not set
National Taiwan Uni Hospital; General Surgery, Taipei, Not set
Ankara Bilkent City Hospital, Ankara, Not set
Dicle Uni Medical Faculty; Internal Medicine, Diyarbakir, Not set
Medipol University Medical Faculty; Oncology Department, Istanbul, Not set
Prof. Dr. Cemil Tascioglu City Hospital; Med Onc, Istanbul, Not set
Katip Celebi University Ataturk Training and Research Hospital; Oncology, Izmir, Not set
Sakarya University Medical School; Medical Oncology, Sakarya, Not set
Chemotherapy SI Dnipropetrovsk MA of MOHU, Dnipropetrovsk, Not set
Kyiv City Clinical Oncological Center, Day Hospital Department for Oncological patients, Kiev, Not set
National Cancer Institute MOH of Ukraine, Kiev, Not set
Lviv State Oncological Regional Treatment and Diagnostic Center, Lviv, Not set
Velindre Cancer Centre, Cardiff, Not set
University Hospital coventry; Oncology Department, Coventry, Not set
The Beatson West of Scotland Cancer Centre; Cancer Clinical Trials Unit, Glasgow, Not set
Royal Marsden Hospital - London, London, Not set
Derriford Hospital, Plymouth, Not set
Royal Stoke University Hospital, Stoke-on-Trent, Not set
Royal Marsden Hospital; Dept of Medical Oncology, Sutton, Not set
Conditions: Breast Cancer
Basket Study of Neratinib in Participants With Solid Tumors Harboring Somatic HER2 or EGFR Exon 18 Mutations
Terminated
This is an open-label, multicenter, multinational, Phase 2 basket study exploring the efficacy and safety of neratinib as monotherapy or in combination with other therapies in participants with HER (EGFR, HER2) mutation-positive solid tumors.
This is an open-label, multicenter, multinational, Phase 2 basket study exploring the efficacy and safety of neratinib as monotherapy or in combination with other therapies in participants with HER (EGFR, HER2) mutation-positive solid tumors. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/12/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama +59 locations
University of Alabama at Birmingham, Birmingham, Alabama
Mayo Clinic Arizona, Phoenix, Arizona
City of Hope, Duarte, California
University of California, San Diego, La Jolla, California
University of Southern California, Los Angeles, California
University of California, Los Angeles, Los Angeles, California
Stanford Cancer Center, Palo Alto, California
UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California
Kaiser Permanente NoCal (STRATA), Vallejo, California
Mayo Clinic Florida, Jacksonville, Florida
University of Miami, Miami, Florida
Winship Cancer Institute, Emory University, Atlanta, Georgia
Northwestern University, Chicago, Illinois
Ochsner Clinic Foundation, New Orleans, Louisiana
Dana Farber Cancer Institute, Boston, Massachusetts
University of Michigan, Ann Arbor, Michigan
Mayo Clinic, Rochester, Minnesota
Metro Minnesota Community Oncology Research Consortium, Saint Louis Park, Minnesota
Washington University, Saint Louis, Missouri
Roswell Park Comprehensive Cancer Center, Buffalo, New York
Memorial Sloan-Kettering Cancer Center, New York, New York
UPMC Magee-Woman's Hospital, Women's Cancer Center, Pittsburgh, Pennsylvania
Saint Francis Cancer Center-Bon Secours, Greenville, South Carolina
The West Clinic, Germantown, Tennessee
Vanderbilt-Ingram Cancer Center, Nashville, Tennessee
UT Southwestern Medical Center, Dallas, Texas
MD Anderson Cancer Center, Houston, Texas
Seattle Cancer Care Alliance, Seattle, Washington
Gundersen Center for Cancer and Blood Disorders, La Crosse, Wisconsin
University of Wisconsin Carbone Cancer Center, Madison, Wisconsin
Peter MacCallum Cancer Centre, East Melbourne, Victoria
UZ Leuven, Leuven, Not set
British Columbia Cancer Center, Vancouver, British Columbia
University Hospital, Rigshospitalet, Kopenhagen, Not set
Institut Curie - Hopital Rene Huguenin, Saint-Cloud, Ile De France
Institut Gustave Roussy, Villejuif, Paris
Institut Bergonié, Bordeaux, Not set
Centre Leon Berard, Lyon, Not set
St. Vincent's University Hospital, Dublin, Leinster
Hadassah Medical Center, Jerusalem, Not set
Davidoff Cancer Center, Rabin Medical Center, Petah Tikva, Not set
Sheba Medical Center, Ramat Gan, Not set
Kaplan Medical Center, Rehovot, Not set
Sourasky Medical Center, Tel Aviv, Not set
Azienda Socio Sanitaria Territoriale di Cremona, Cremona, Not set
Istituto Europeo di Oncologia (IEO) I.R.C.C.S., Milano, Not set
Fondazione Policlinico Universitario Gemelli I.R.C.C.S., Roma, Not set
AOU Citta della Salute e della Scienza di Torino, Torino, Not set
Yonsei University Health System, Serverance Hospital, Seodaemun-Gu, Seoul
Institute for Oncology and Radiology of Serbia, Belgrade, Not set
Hospital Universitario Quiron Dexeus, Barcelona, Not set
Hospital Universitario Vall d'Hebron, Barcelona, Not set
Hospital Universitari Clinic Barcelona, Barcelona, Not set
Hospital Clinico Universitario San Carlos, Madrid, Not set
Hospital Universitario Fundacion Jimenez Diaz, Madrid, Not set
Hospital Universitario Madrid Sanchinarro (START Madrid), Madrid, Not set
Hospital Universitario Quiron Madrid, Madrid, Not set
Instituto Valenciano de Oncologia, Valencia, Not set
Hospital Clinico Universitario de Valencia, Valencia, Not set
Royal Free Hospital, London, Not set
Conditions: Solid Tumors Harboring Somatic HER2 or EGFR Exon 18 Mutations
Using Genetic Profile to Determine the Treatment for Patients With Ovarian Cancer Who Previously Received a PARP-inhibitor
Recruiting
The purpose of this research study is to see how useful it is to look at biomarkers in the blood and tumor tissue of participants with ovarian, fallopian tube or primary peritoneal cancer who have previously received treatment with a drug called a PARP inhibitor, and using the results to determine the best treatment for these participants. Biomarkers are molecules such as genes (molecules that contain instructions for the development and function of cells in the body) and proteins that may be us... Read More
The purpose of this research study is to see how useful it is to look at biomarkers in the blood and tumor tissue of participants with ovarian, fallopian tube or primary peritoneal cancer who have previously received treatment with a drug called a PARP inhibitor, and using the results to determine the best treatment for these participants. Biomarkers are molecules such as genes (molecules that contain instructions for the development and function of cells in the body) and proteins that may be used to see how well a body responds to certain treatments. Read Less
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
01/14/2024
Locations: Princess Margaret Cancer Centre, Toronto, Ontario
Princess Margaret Cancer Centre, Toronto, Ontario
Conditions: Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer, High Grade Serous Cancer, High Grade Endometrioid Cancer
M7824 With cCRT in Unresectable Stage III Non-small Cell Lung Cancer (NSCLC)
Terminated
The main purpose of this study was to evaluate safety and efficacy in participants treated with concomitant chemoradiation therapy (cCRT) plus M7824 followed by M7824 compared to cCRT plus placebo followed by durvalumab.
The main purpose of this study was to evaluate safety and efficacy in participants treated with concomitant chemoradiation therapy (cCRT) plus M7824 followed by M7824 compared to cCRT plus placebo followed by durvalumab. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/12/2024
Locations: University of California Irvine Medical Center, Orange, California +103 locations
University of California Irvine Medical Center, Orange, California
UCLA Hematology Oncology - Main Site - 2020 Santa Monica, Santa Monica, California
University of Colorado Health - Memorial Hospital - Memorial Hospital, Colorado Springs, Colorado
Hematology Oncology Associates, Fort Collins, Colorado
Lynn Cancer Institute Center, Boca Raton, Florida
Holy Cross Hospital - Michael and Dianne Bienes CCC, Fort Lauderdale, Florida
Sylvester Comprehensive Cancer Center - University of Miami Health System, Miami, Florida
The University of Chicago Medical Center, Chicago, Illinois
American Health Network of Indiana, LLC, Indianapolis, Indiana
Franciscan St. Francis Health Cancer Center, Indianapolis, Indiana
Baptist Health Lexington Oncology Associates, Lexington, Kentucky
University of Maryland - DUPLICATE/Pediatric Surgery, Baltimore, Maryland
Henry Ford Health System, Detroit, Michigan
Mayo Clinic, Rochester, Minnesota
Columbia University Medical Center, New York, New York
Hematology Oncology Center of Nyack Hospital, Nyack, New York
FirstHealth of the Carolinas, Inc., Pinehurst, North Carolina
The James Cancer Hospital and Solove Research Institute, Columbus, Ohio
UPMC Cancer Center, Pittsburgh, Pennsylvania
Vanderbilt University Medical Center, Nashville, Tennessee
University of Texas MD Anderson Cancer Center - Unit 432 Thoracic Head and Neck Medical Oncology, Houston, Texas
Sanatorio Allende, Cordoba, Not set
Centro Polivalente de Asistencia e Inv. Clinica CER, San Juan, Not set
Bendigo Hospital, Bendigo, Not set
The Townsville Hospital, Douglas, Not set
Calvary Central Districts Hospital, Elizabeth Vale, Not set
St Vincent's Hospital Melbourne - PARENT, Fitzroy, Not set
University Hospital Geelong - PARENT, Geelong, Not set
Austin Health, Heidelberg Heights, Not set
Centro de Investigacion Pergamino SA, Pergamino, Not set
Prince of Wales Hospital, Randwick, Not set
Sunshine Hospital, St Albans, Not set
Royal North Shore Hospital, St Leonards, Not set
South West Healthcare - South West Oncology, Warrnambool, Not set
UZ Leuven, Leuven, Not set
Clinique et Maternite St Elisabeth Namur, Namur, Not set
AZ Delta, Roeselare, Not set
CHU Mont-Godinne, Yvoir, Not set
Hospital de Câncer de Barretos - Fundação Pio XII, Barretos, Not set
Clínica de Neoplasias Litoral Ltda., Itajaí, Not set
HGB - Hospital Giovanni Battista - Mãe de Deus Center - Centro de Pesquisa Clínica - Instituto do Câncer, Porto Alegre, Not set
Hospital São Lucas da PUCRS, Porto Alegre, Not set
COI - Clínicas Oncológicas Integradas, Rio de Janeiro, Not set
A. C. Camargo Cancer Center - Fundação Antônio Prudente, São Paulo, Not set
ICESP - Instituto do Câncer do Estado de São Paulo Octavio Frias de Oliveira, São Paulo, Not set
BC Cancer Agency Center for the Southern Interior, Kelowna, Not set
Peking University Cancer Hospital, Beijing, Not set
Jilin Cancer Hospital - Oncology, Changchun, Not set
Hangzhou First People's Hospital, Hangzhou, Not set
Fakultni nemocnice Olomouc - Dept of Onkologicka klinika, Olomouc, Not set
Centre Hospitalier de la Côte Basque - Service de Pneumologie, Bayonne, Not set
Hôpital Nord - AP-HM Marseille# - Service d'Oncologie Multidisciplinaire, Marseille cedex 20, Not set
Institut Curie - Centre de Lutte Contre le Cancer (CLCC) de Paris - Service d'Oncologie Médicale, Paris Cedex 05, Not set
CHU Nantes - Hôpital Guillaume et René Laënnec - Service de Pneumologie, Saint Herblain, Not set
Asklepios Klinik Harburg - Medizinische Abteilung I, Hamburg, Not set
Pius-Hospital Oldenburg - Klinik f. Haematologie und Onkologie, Oldenburg, Not set
Nippon Medical School Hospital - Dept of Respiratory Medicine, Bunkyo-ku, Not set
Tokyo Metropolitan Cancer and Infectious diseases Center Komagome Hospital - Dept of Respiratory Medicine, Bunkyo-ku, Not set
Saitama Medical University International Medical Center - Dept of Respiratory Medicine, Hidaka-shi, Not set
National Cancer Center Hospital East - Dept of Respiratory Medicine, Kashiwa-shi, Not set
Kobe City Hospital Organization Kobe City Medical Center General Hospital - Dept of Respiratory Medicine, Kobe-shi, Not set
Cancer Institute Hospital of JFCR - Dept of Respiratory Medicine, Koto-ku, Not set
Kurume University Hospital - Dept of Lung Cancer Center, Kurume-shi, Not set
Aichi Cancer Center Hospital - Dept of Respiratory Medicine, Nagoya-shi, Not set
Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka-shi, Not set
Kindai University Hospital (13859), Osakasayama-shi, Not set
Shizuoka Cancer Center, Sunto-gun, Not set
Kanagawa Cancer Center - Dept of Respiratory Medicine, Yokohama-shi, Not set
Keimyung University Dongsan Hospital, Daegu, Not set
Seoul National University Bundang Hospital, Seongnam, Not set
Asan Medical Center, Seoul, Not set
Korea University Anam Hospital, Seoul, Not set
Severance Hospital, Yonsei University, Seoul, Not set
The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul, Not set
Jeroen Bosch Ziekenhuis, 's Hertogenbosch, Not set
Meander Medisch Centrum - Dep of Pulmonology, Amersfoort, Not set
Amphia Ziekenhuis - PARENT - Parent, Breda, Not set
Martini ziekenhuis, Groningen, Not set
Ziekenhuis St. Jansdal, Harderwijk, Not set
St. Antonius Ziekenhuis - Dept Pulmonology - Nieuwegein, Nieuwegein, Not set
St. Elisabeth Ziekenhuis - Parent, Tilburg, Not set
ISALA Klinieken Locatie Sophia, Zwolle, Not set
Hospital del Mar - Servicio de Oncologia, Barcelona, Not set
Hospital Universitari Quiron Dexeus - Servicio de Oncologia Medica, Barcelona, Not set
Hospital Universitari Vall d'Hebron - Dept of Oncology, Barcelona, Not set
ICO l´Hospitalet - Hospital Duran i Reynals - Servicio de Oncologia, L'Hospitalet de Llobregat, Not set
Clinica Universidad de Navarra (MAD) - Oncology Service, Madrid, Not set
Hospital Universitario 12 de Octubre - Servicio de Oncologia, Madrid, Not set
Hospital Universitario Clinico San Carlos - Servicio de Oncologia, Madrid, Not set
Hospital Universitario HM Madrid Sanchinarro - Servicio de Oncologia, Madrid, Not set
Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda, Not set
Hospital Regional Universitario de Malaga, Málaga, Not set
Clinica Universidad de Navarra, Pamplona, Not set
Complejo Hospitalario Universitario de Santiago - Servicio de Oncologia Medica, Santiago de Compostela, Not set
Hospital Universitario Nuestra Señora de Valme - Servicio de Oncologia, Sevilla, Not set
Hospital Universitario Virgen del Rocio - Servicio de Oncologia, Sevilla, Not set
Hospital Universitario Virgen Macarena - Servicio de Oncologia, Sevilla, Not set
Hospital Clinico Universitario de Valencia - Servicio de Hematologia y Oncologia Medica, Valencia, Not set
Hospital Universitari i Politecnic La Fe - Servicio de Oncologia Medica, Valencia, Not set
Hospital Alvaro Cunqueiro - Servicio de Oncologia, Vigo, Not set
Taichung Veterans General Hospital, Taichung, Not set
Chi Mei Medical Center, Liou Ying, Tainan, Not set
National Taiwan University Hospital, Taipei, Not set
Tri-Service General Hospital, Taipei, Not set
Conditions: Non-small Cell Lung Cancer
A Study of BBI608 Plus Weekly Paclitaxel to Treat Gastric and Gastro-Esophageal Junction Cancer
Completed
The purpose of this study is to find out whether it is better to receive a new drug, BBI608, in addition to paclitaxel chemotherapy or better to receive paclitaxel chemotherapy alone as second line treatment for gastric and gastroesophageal junction cancer after prior first line platinum and fluoropyrimidine based chemotherapy.
The purpose of this study is to find out whether it is better to receive a new drug, BBI608, in addition to paclitaxel chemotherapy or better to receive paclitaxel chemotherapy alone as second line treatment for gastric and gastroesophageal junction cancer after prior first line platinum and fluoropyrimidine based chemotherapy. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/13/2023
Locations: Mayo Clinic - Arizona, Scottsdale, Arizona +262 locations
Mayo Clinic - Arizona, Scottsdale, Arizona
Colorado Cancer Research Program, Denver, Colorado
Indiana University Health Goshen Center For Cancer Care, Goshen, Indiana
Northern Indiana Cancer Research Consortium, South Bend, Indiana
Siouxland Regional Cancer Center, Sioux City, Iowa
Cancer Center of Kansas, Wichita, Kansas
Ochsner NCI CORP, New Orleans, Louisiana
Spectrum Health Butterworth, Grand Rapids, Michigan
Munson Medical Center, Traverse City, Michigan
Mayo Clinic - Rochester, Rochester, Minnesota
Metro-Minnesota NCI CORP, Saint Louis Park, Minnesota
Heartland NCORP, Saint Louis, Missouri
New Hampshire Oncology Hematology - Concord, Concord, New Hampshire
New Hampshire Oncology Hematology - Laconia, Laconia, New Hampshire
Weill Medical College of Cornell University, New York, New York
State University of New York Upstate Medical University, Syracuse, New York
Indiana University Health University Hospital, Chapel Hill, North Carolina
Ohio State University Medical Center, Columbus, Ohio
The University of Oklahoma Health Sciences Center (OUHSC), Oklahoma City, Oklahoma
Geisinger Medical Center, Danville, Pennsylvania
Virginia Mason Medical Center, Seattle, Washington
Swedish Cancer Institute/ Swedish Health Services, Seattle, Washington
Saint Vincent Hospital CCOP, Green Bay, Wisconsin
St. Mary's Hospital, Green Bay, Wisconsin
Gundersen Lutheran Medical Center, La Crosse, Wisconsin
Marshfield CCOP, Marshfield, Wisconsin
Bankstown-Lidcombe, Bankstown, New South Wales
Chris O'Brien Lifehouse, Camperdown, New South Wales
St Vincent's Hospital, Darlinghurst, New South Wales
Central coast area health (public), Gosford, New South Wales
Port Macquaries Base Hospital, Port Macquarie, New South Wales
Royal North Shore Hospital, St Leonards, New South Wales
Riverina Cancer Care Centre, Wagga Wagga, New South Wales
Royal Brisbane & Women's Hospital, Herston, Queensland
Sunshine Coast Hospital and Health Service, Nambour, Queensland
Gold Coast University Hospital, Southport, Queensland
Townsville Hospital, Townsville, Queensland
Princess Alexandra Hospital, Woolloongabba, Queensland
Flinders Medical Centre, Bedford Park, South Australia
Ashford Cancer Centre Research, Kurralta Park, South Australia
The Queen Elizabeth Hospital, Woodville, South Australia
Bendigo Hospital, Bendigo, Victoria
Monash Health, East Bentleigh, Victoria
Peninsula & South Eastern Haematology and Oncology Group, East Bentleigh, Victoria
St Vincent's Hospital, Fitzroy, Victoria
Austin Hospital, Heidelberg, Victoria
Ballarat base hospital, Heidelberg, Victoria
Royal Melbourne Hospital, Parkville, Victoria
Sunshine Hospital, St Albans, Victoria
Ballarat Oncology and Haematology Services, Wendouree, Victoria
Fiona Stanley Hospital, Subiaco, Western Australia
Imelda Ziekenhuis, Bonheiden, Antwerpen
UZ Antwerpen, Edegem, Antwerpen
UZ Brussel - Campus Jette, Brussel, Brussels Capital Region
Institut Jules Bordet, Bruxelles, Brussels Capital Region
Cliniques Universitaires Saint-Luc, Bruxelles, Brussels Capital Region
CHU Ambroise Paré, Mons, Hainaut
UZ Leuven - Campus Gasthuisberg, Leuven, Vlaams Brabant
AZ Sint-Lucas - Campus Sint-Lucas, Brugge (Assebroek), Not set
CHU de Liège - Domaine Universitaire du Sart Tilman, Liège, Not set
Oncovida - Centro de Oncologia da Bahia, Salvador, Bahia
Instituto do Câncer do Ceará - Instituto do Câncer do Cear, Fortaleza, Ceará
Cetus Hospital Dia Oncologia, Belo Horizonte, Minas Gerais
Hospital Erasto Gaertner, Curitiba, Paraná
Hospital Bruno Born, Lajeado, Rio Grande Do Sul
Hospital da Cidade de Passo Fundo, Passo Fundo, Rio Grande Do Sul
UPCO - Unidade de Pesquisa Clinica em Oncologia LTDA, Pelotas, Rio Grande Do Sul
Clinica de Neoplasias Litoral, Itajai, Santa Catarina
Fundaçao dr Amaral Carvalho, Jaú, São Paulo
Hospital de Base de São José do Rio Preto, São José do Rio Preto, São Paulo
Inca-RJ, Rio de Janeiro, Not set
IEP São Lucas, São Paulo, Not set
Casa de Saúde Santa Marcelina, São Paulo, Not set
Specialised Hospital for Active Treatment in Oncology, Sofia, Sofia-Grad
UMHAT ""Dr. Georgi Stranski"" Dept. Medical Oncology, Pleven, Not set
District Dispensery with Stationary - Sofia District, Sofia, Not set
Multiprofile hospital for active treatment, Sofia, Not set
UMHAT"Sv.Ivan Rilski", Sofia, Not set
Uni. Multiprofile Hospital for Active treatment Sveta Marina, Varna, Not set
COC - Vratsa Dept. of Palliative Care, Vratsa, Not set
The Ottawa Hospital Cancer Centre, Ottawa, Ontario
Saint Michael's Hospital Li Ka Shing Knowledge Institute, Toronto, Ontario
Mount Sinai Hospital, Toronto, Ontario
Princess Margaret Hospital, Toronto, Ontario
Hopital Notre-Dame du CHUM, Montreal, Quebec
McGill University Health Centre - Montreal General Hospital, Montreal, Quebec
Cancer Hospital Chinese Academy of Medical Sciences, Beijing, Beijing
The 307th Hospital of Chinese People's Liberation Army, Beijing, Beijing
Beijing Cancer Hospital, Beijing, Beijing
Chinese PLA General Hospital, Beijing, Beijing
Fujian Medical University Union Hospital, Fuzhou, Fujian
Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong
Southern Medical University, Nanfang Hospital, Guangzhou, Guangdong
Harbin Medical University Cancer Hospital, Heilongjiang, Heilongjiang
The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan
Henan Cancer Hospital, Zhengzhou, Henan
Hunan Cancer Hospital, Changsha, Hunan
The 81 Hospital of the Chinese People's Liberation Army, Nanjing, Jiangsu
Jiang Su Cancer Hospital, Nanjing, Jiangsu
Jiangsu Province Hospital, Nanjing, Jiangsu
The First Bethune Hospital of Jilin University, Changchun, Jilin
Jilin Cancer Hospital, Jilin, Jilin
The First Hospital of China Medical University, Shenyang, Liaoning
General Hospital of Ningxia Medical University, Yinchuan, Ningxia
Fudan University Shanghai Cancer Center, Shanghai, Shanghai
Zhongshan Hospital, Shanghai, Shanghai
West China Hospital, Sichuan University, Chengdu, Sichuan
Tianjin Medical University Cancer Institute & Hospital, Tianjin, Tianjin
Xin Jiang Tumor Hospital, Xin Jiang Medical University, Urumqi, Xinjiang
Sir Run Run Shaw Hospital School of Medicine, Zhejiang University, Hangzhou, Zhejiang
Zhejiang Cancer Hospital, Hangzhou, Zhejiang
Tongji Hospital, Wuhan, Not set
FN Hradec Kralove, Hradec Kralove, Královéhradecký Kraj
Fakultni nemocnice Olomouc, Olomouc, Olomoucký Kraj
Masarykuv onkologicky ustav, Brno, Not set
Vseobecna fakultni nemocnice v Praze, Praha 2, Not set
Nemocnice Na Bulovce, Praha 8, Not set
East Tallinn Central Hospital Oncology Center, Tallinn, Harjumaa
Tartu University Hospital Clinic of Hematology and Oncology, Tartu, Tartumaa
Centre Antoine Lacassagne, Nice, Alpes-Maritimes
Hopital Saint Joseph - Marseille, Marseille, Bouches-du-Rhône
Centre Paul Papin, St Herblain Cedex, Loire-Atlantique
Centre Rene Gauducheau, St Herblain Cedex, Loire-Atlantique
Hopital Privé Jean Mermoz, Lyon, Rhône
Chd Vendee La Roche Sur Yon, La Roche sur Yon Cedex 9, Vendée
Hospital of Poitiers, Poitiers, Vienne
Hôpital Morvan - CHRU de Brest, Brest Cedex, Not set
CHU Estaing, Clermont-Ferrand, Not set
CHU - Hôpital De La Timone, Marseille, Not set
Centre Hospitalier De Mont De Marsan - Hopital Layné, Mont de Marsan Cedex, Not set
Centre eugène marquis, Rennes, Not set
CHU Saint Etienne, Saint Etienne, Not set
Centre Hospitalier Universitaire (CHU) de Toulouse - Hopital, Toulouse cedex, Not set
Institut Gustave Roussy, Villejuif, Not set
Klinikum Bogenhausen, München, Bayern
Klinikum der Johann Wolfgang Goethe-Universität, Frankfurt/Main, Hessen
Ev. Krankenhaus Bielefeld, Bielefeld, Nordrhein-Westfalen
Kliniken Essen-Mitte Evang. Huyssens-Stiftung, Essen, Nordrhein-Westfalen
Johannes Gutenberg-Universitaet, Maintz, Rheinland-Pfalz
Universitätsklinik Carl-Gustav-Carus Dresden, Dresden, Sachsen
Universitätsklinikum Leipzig, Leipzig, Sachsen
Charite - Campus Benjamin Franklin (Cbf), Berlin, Not set
Charite, Berlin, Not set
Klinikum Esslingen, Esslingen, Not set
Facharztzentrum Eppendorf, Hamburg, Not set
OncoResearch Lerchenfeld GmbH, Hamburg, Not set
Pécsi Tudományegyetem Klinikai Központ, Pécs, Baranya
Békés Megyei Pándy Kálmán Kórház, Gyula, Békés
Petz Aladár Megyei Oktató Kórház, Gyor, Gyor-Moson-Sopron
Debreceni Egyetem Klinikai Központ, Debrecen, Hajdú-Bihar
Jász-Nagykun-Szolnok Megyei Hetényi Géza Kórház- Rendelőinté, Szolnok, Jász-Nagykun-Szolnok
Josa Andras Oktato Korhaza, Nyiregyhaza, Szabolcs-Szatmár-Bereg
Semmelweis Egyetem, Budapest, Not set
Egyesített Szent István és Szent László Kórház-Rendelőintéze, Budapest, Not set
Országos Onkológiai Intézet, Budapest, Not set
Semmelweis Egyetem, Budapest, Not set
Somogy Megyei Kaposi Mór Oktató Kórház, Kaposvár, Not set
Soroka Medical Center [Oncology], Beer Sheva, HaDarom
The E. Wolfson Medical Center [Oncology], Holon, HaMerkaz
Meir Medical Center, Kfar Saba, HaMerkaz
Rabin Medical Center - Beilinson Hospital, Petah Tikva, HaMerkaz
Tel Aviv Sourasky Medical Center, Tel Aviv, Tel-Aviv
Hadassah Medical Organisation, Jerusalem, Yerushalayim
Rambam Health Care Campus, Haifa, Not set
Irccs Irst, Meldola, Forli
AUSL della Romagna, Osp. degli Infermi, Faenza, Ravenna
Ospedale Umberto I, AOU Ospedali Riuniti Umberto I - GM.Lanc, Ancona, Not set
IRCCS Ospedale Oncologico "Giovanni Paolo II", Bari, Not set
Humanitas Gavazzeni, Bergamo, Not set
Policlinico S.Orsola Malpighi, AOU di Bologna, Bologna, Not set
PO Garibaldi-Nesima, ARNAS Garibaldi, Catania, Not set
Azienda Ospedaliera "Istituti Ospitalieri" di Cremona, Cremona, Not set
AOU S.Martino, IRCCS, IST-Istituto Nazionale Ricerca Sul Can, Genova, Not set
Azienda Ospedaliera Fatebenefratelli e Oftalmico, Milano, Not set
Istituto Oncologico Veneto IOV-IRCCS, Padova, Not set
Ospedale Guglielmo da Saliceto, AUSL Piacenza, Piacenza, Not set
Unità di Biostatistica e Sperimentazioni Cliniche IRST, Ravenna, Not set
Ospedale Molinette, AO Città della Salute e della Scienza di, Torino, Not set
Aichi Cancer Center Hospital, Nagoya, Aichi
National Cancer Center Hospital East, Kashiwa, Chiba
National Hospital Organization Shikoku Cancer Center, Matsuyama, Ehime
Hokkaido University Hospital, Sapporo, Hokkaido
Kobe City Medical Center General Hospital, Kobe, Hyogo
Saku Central Hospital Advanced Care Center, Saku, Nagano
Osaka University Hospital, Suita, Osaka
Saitama Cancer Center, Kita-Adachi, Saitama
Shizuoka Cancer Center, Sunto, Shizuoka
Tochigi Cancer Center, Utsunomiya, Tochigi
National Cancer Center Hospital, Chuo, Tokyo
Kyorin University Hospial, Mitaka, Tokyo
Chiba Cancer Center, Chiba, Not set
Gifu University Hospital, Gifu, Not set
Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Not set
Seoul National University Bundang Hospital, SeongNam, Gyeonggido
Samsung Medical Center, Seoul, Seoul Teugbyeolsi
Asan medical Center, Seoul, Seoul Teugbyeolsi
Seoul National University Hospital, Seoul, Seoul Teugbyeolsi
Hospital of Lithuanian University of Health sciences, Kaunas, Kauno Apskritis
Hospital of Lithuanian University of Health Sciences, Kaunas, Kauno Apskritis
Respublikine Panevezio ligonine, Panevezys, Panevežio Apskritis
National Cancer Institute, Vilnius, Vilniaus Apskritis
Klaipeda University Hospital, Klaipeda, Not set
Vilniaus Universiteto ligonines Santariskiu Klinikos, Vilnius, Not set
Siauliai County Hospital, Siauliai, Šiauliu Apskritis
Centrum Onkologii im. F.Lukaszczyka, Bydgoszcz, Kujawsko-pomorskie
Szpital Specjalistyczny im. L. Rydygiera w Krakowie, Krakow, Malopolskie
Europejskie Centrum Zdrowia Otwock, Szpital im. F. Chopina, Otwock, Mazowieckie
Centrum Onkologii Instytut im. M. Sklodowskiej-Curie, Warszawa, Mazowieckie
Magodent sp. z o.o. Szpital Onkologiczny, Warszawa, Mazowieckie
Szpital Specjalistyczny w Brzozowie Podkarpacki Ośrodek Onko, Brzozow, Podkarpackie
Wojewodzkie Centrum Onkologii w Gdansku, Gdansk, Pomorskie
NZOZ Centrum Medyczne HCP Lecznictwo Stacjonarne, Poznan, Wielkopolskie
Zachodniopomorskie Centrum Onkologii, Szczecin, Zachodniopomorskie
Wojewodzki Szpital Specjalistyczny im. M.Kopernika, Lodz, Łódzkie
Radiotherapy Center CJ radioterapie si chimioterapie adulti, Floresti, Cluj
Centrul de Oncologie Sf. Nectarie, Craiova, Dolj
Oncolab, Craiova, Dolj
Sp. Jud. de Urg. "Dr. Constantin Opris" Baia Mare, Baia-Mare, Maramures
Oncomed, Timisoara, Timis
Spitalul Clinic Municipal de Urgenta Timisoara, Timisoara, Timis
Med Life, Bucuresti, Not set
Spitalul Clinic CF 2, Bucuresti, Not set
Institutul Clinic Fundeni, Bucuresti, Not set
Centrul de Oncologie Euroclinic, Iasi, Not set
Institutul Regional de Oncologie Iasi, Lasi, Not set
Spitalul Clinic Judetean de Urgenta Sibiu, Sibiu, Not set
Republican Clinical Oncology Dispensary, Ufa, Bahkortostan, Respublika
Military Medical Academy n.a. S.M. Kirov, Saint Petersburg, Leningradskaya Oblast'
Russian Oncological Research Center n.a. N.N. Blokhin RAMS, Moscow, Moskva
City Clinical Hospital #40, Moscow, Moskva
GUZ Perm Regional Oncology Dispensary, Perm, Permskiy Kray
Northwestern State Medical University n.a. Mechnikov, Saint Petersburg, Sankt-Peterburg
First Pavlov State Medical University of Saint-Petersburg, Saint Petersburg, Sankt-Peterburg
GBUZ Saint Petersburg clinical scientific and practical cent, Saint Petersburg, Sankt-Peterburg
SPb State Budget Institution Oncology Dispansery, Saint Petersburg, Sankt-Petersburg
GBUZ of Stavropol Territory Pyatigorsk Oncology Dispensary, Pyatigorsk, Stavropol'skiy Kray
Guz Clinical Oncology Dispensary #1, Krasnodar, Not set
H.U.V. Macarena, Sevilla, Andalucía
Institut Català d'Oncologia-Hospital Germans Trias i Pujol, Badalona, Barcelona
C.A.AV-H.Ntra.Sra.de Sonsoles, Avila, Castilla Y León
H.U.P Hierro-Majadahonda, Majadahonda, Madrid
H.del Mar, Barcelona, Not set
Hospital Universitario Vall d'Hebrón, Barcelona, Not set
H.Sta.Creu i St.Pau, Barcelona, Not set
H.U. de Burgos, Burgos, Not set
Institut Catalá d´Oncología (I.C.O.), Hospitalet de Llobregat, Not set
H.G.U. G. Marañón, Madrid, Not set
M.D. Anderson Cancer Center Madrid, Madrid, Not set
H.U. R. y Cajal, Madrid, Not set
H.C. S.Carlos, Madrid, Not set
H.U.V.Arrixaca, Murcia, Not set
H.U.V. del Rocío, Sevilla, Not set
C.H.G.U.de Valencia, Valencia, Not set
H.U. Miguel Servet, Zaragoza, Not set
Aberdeen Royal Infirmary, Aberdeen, Aberdeen City
The Beatson West Of Scotland Cancer Centre, Glasgow, Glasgow City
Royal Surrey County Hospital, Guildford, Surrey
The Royal Marsden Hospital, Sutton, Surrey
The Royal Marsden NHS Foundation Trust - Royal Marsden Hospital, Sutton, Surrey
Belfast City Hospital, Belfast, Not set
St. Georges Hospital, London, Not set
Christie Hospital NHS Foundation Trust, Manchester, Not set
Southampton University Hospital, Southampton, Not set
Conditions: Gastric Cancer, Gastroesophageal Junction Cancer
A Study of BBI503 in Combination With Selected Anti-Cancer Therapeutics in Adult Patients With Advanced Cancer
Completed
This is an open label, multi-center, Phase 1/2 study of BBI503 administered in combination with selected anti-cancer therapeutics in adult patients with advanced cancer. The goal of the study is to determine the safety, tolerability, and RP2D of BBI503 in combination with each of the selected anti-cancer agents.
This is an open label, multi-center, Phase 1/2 study of BBI503 administered in combination with selected anti-cancer therapeutics in adult patients with advanced cancer. The goal of the study is to determine the safety, tolerability, and RP2D of BBI503 in combination with each of the selected anti-cancer agents. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/13/2023
Locations: Parkview Research Center, Fort Wayne, Indiana +7 locations
Parkview Research Center, Fort Wayne, Indiana
Indiana University Health Goshen, Goshen, Indiana
Indiana University -Ball, Indianapolis, Indiana
Indiana University-SCC, Indianapolis, Indiana
Louisiana State Univesity, New Orleans, Louisiana
US Oncology Research, Fairfax, Virginia
Ottawa Hospital Research Institute, Ottawa, Ontario
Princess Margaret Cancer Centre, Toronto, Ontario
Conditions: Cancer
A Study of BBI608 Administered With Paclitaxel in Adult Patients With Advanced Malignancies
Completed
This is an open label, single arm phase 1 dose escalation study and phase 2 study of BBI608 in combination with paclitaxel in patients with advanced malignancies.
This is an open label, single arm phase 1 dose escalation study and phase 2 study of BBI608 in combination with paclitaxel in patients with advanced malignancies. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/13/2023
Locations: USC - University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California +21 locations
USC - University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California
Rocky Mountain Cancer Centers, Denver, Colorado
Indiana University Simon Cancer Center, Indianapolis, Indiana
Massachusetts General Hospital Cancer Center, Boston, Massachusetts
Mayo Clinic, Rochester, Minnesota
Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada
New York Oncology Hematology, P.C., Albany, New York
Ohio State University Wexner Medical Center, Columbus, Ohio
Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania
Prisma Health (formerly Institute for Translational Oncology Research), Greenville, South Carolina
University of Tennessee Medical Center Cancer Institute, Knoxville, Tennessee
Texas Oncology- Baylor Charles A. Sammons Cancer Center, Dallas, Texas
Texas Oncology- Fort Worth, Fort Worth, Texas
Texas Oncology- Tyler, Tyler, Texas
Virginia Cancer Specialists, P.C., Fairfax, Virginia
Virginia Oncology Associates, Norfolk, Virginia
Compass Oncology- Northwest Cancer Specialists, Vancouver, Washington
British Columbia Cancer Agency, Vancouver, British Columbia
Ottawa Hospital Cancer Centre, Ottawa, Ontario
Jewish General Hospital, Montreal, Quebec
St. Mary's Hospital, Montreal, Quebec
McGill University Health Center-Glenn Site, Montreal, Quebec
Conditions: Cancer
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