All Clinical Trials in Canada

A listing of 3905 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

Home

Canada

Show Filters

Match to Clinical Trials

Access to cutting-edge treatments

Latest clinical trials

Find trials in your area

Start Matching

Filter by Age

Outcomes of Low-Risk Endometrial Cancer With Isolated Tumor Cells in the Sentinel Lymph Nodes: A Prospective, Multicenter, Single-Arm Observational Study

NCT06689956

Recruiting

This study evaluates whether isolated tumor cells in the first lymph nodes near the tumor can tell researchers something important about the future of patients with a certain type of endometrial (uterine) cancer.

Gender:

ALL

Ages:

All

Trial Updated:

06/25/2025

Locations: Mayo Clinic in Rochester, Rochester, Minnesota +19 locations

Conditions: FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma, FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma, Stage IA1 Endometrial Cancer FIGO 2023, Stage IA2 Endometrial Cancer FIGO 2023

Learn More ›

Type 1 Diabetes, Exercise and Mentoring Trial

NCT06296992

Recruiting

The proposed study aims to improve the psychosocial health of adolescents living with type 1 diabetes (T1D). The study will generate knowledge and support knowledge mobilization about the effectiveness of a novel model of care for psychosocial health and self-management for adolescents living with type 1 diabetes (T1D). The novel model of care is the recruitment and training if young adult mentors to deliver a behavioural intervention that empowers adolescents with T1D to increase daily physical... Read More

Gender:

ALL

Ages:

Between 13 years and 17 years

Trial Updated:

06/25/2025

Locations: the Children's Hospital Research Institute of Manitoba and the University of Manitoba, Winnipeg, Manitoba +1 locations

Conditions: Type 1 Diabetes, Physical Activity

Learn More ›

Effects of Exercise on Thoracic Aneurysms

NCT04197648

Recruiting

Thoracic aneurysm incidence is estimated to 4.5 cases per 100 000. The manifestation as well as natural history of thoracic aneurysm depend on many factors such as its localisation, its diameter, presence of collagen disease and family history. For the ascendant aortic aneurysm, it is often linked to a degeneration of the media arterial layer of the arterial wall. The media degeneration is cause by the degeneration of the elastic fibres, which lead to a weakening of the arterial wall accompanied with dilation. This process is often due to age and is accelerated by high blood pressure. Amongst the numerous factors causing the aneurysm, the investigators find: hypertension, aortic bicuspid valve, smoking, atherosclerosis, trauma and genetic predisposition. The average growth rate of thoracic aneurysm is 0.1-0.2 cm/year. The risk of rupture is associated to the size of the aneurysm as well as patient's symptoms. The ruptures and dissections rates are accounted for 2-3/year for thoracic aneurysm between 5.5-6.0 cm in diameter. The patients are often limited in their daily life activities considering their concern and risk of rupture and/or dissect. The effects of exercise on the progression of the aneurysm dilation in patients with thoracic ascendant aortic aneurysm are unknown. It is well known that high blood pressure is a risk factor for rupture of the aortic aneurysm. Many studies have demonstrated the benefits of physical exercise regarding the lowering impact of blood pressure in a cardiac hypertensive population. At 3 and 6 months of the intervention, the subjects in the exercise group will have: 1) a lowered blood pressure at rest and during exercise, 2) maintenance/ improvement of muscle strength, 3) improvement of aerobic exercise capacity (VO2max), and 4) aortic dilation that remained stable or comparable to the control group. The research objective is to measure and compare to a control group, the effects of an exercise program on the following parameters: blood pressure response at rest and during exercise, as well as the VO2max at 3 and 6 months time of the intervention. This randomised and prospective study will take place at the " Institut Universitaire de Cardiologie et de Pneumologie du Québec (IUCPQ) " and will include patients who have a non-surgical ascendant thoracic aortic aneurysm (ATAA). The selected subjects will be randomised into two groups: 1) exercise group (n=15), and 2) control group (n=15). Both groups will be met prior to the intervention (baseline) and at 3 and 6 months time of the intervention, and measures described below will be recorded. Read Less

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/25/2025

Locations: Institut universitaire de cardiologie et de pneumologie de Québec - Université Laval, Québec, Quebec +1 locations

Conditions: Thoracic Aortic Aneurysm

Learn More ›

Study of BB-031 in Acute Ischemic Stroke Patients (RAISE)

NCT06226805

Recruiting

The purpose of this study is to evaluate the safety and tolerability of ascending doses (Part A) and selected doses (Part B) of BB-031 in acute ischemic stroke patients presenting within 24 hours of stroke onset. Participants will be randomized to receive one dose of either the investigational drug or placebo and will be followed for 90 days. A total of 156 patients are planned in this study.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/25/2025

Locations: Mills Peninsula Medical Center, Burlingame, California +14 locations

Conditions: Acute Ischemic Stroke

Learn More ›

A Prospective, Multicenter, Single-arm MAC-PD Cohort: a NTM-NET and ESGMYC Collaborative Study

NCT05906316

Recruiting

To gain insight in the effectiveness of, adherence and adjustments to guideline-based three-drug antimycobacterial therapy in patients with Mycobacterium avium complex pulmonary disease (MAC-PD) during the first 6 months of treatment.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/25/2025

Locations: Oregon Science and Health University, Portland, Oregon +10 locations

Conditions: Mycobacterium Avium Complex Pulmonary Disease

Learn More ›

Safety, Pharmacokinetics, and Efficacy of AT 1501 in Patients Undergoing Kidney Transplant

NCT05027906

Recruiting

This study will evaluate the safety, PK, and efficacy of AT 1501 in patients undergoing kidney transplantation.

Gender:

ALL

Ages:

Between 18 years and 100 years

Trial Updated:

06/25/2025

Locations: University of Cincinnati, Cincinnati, Ohio +8 locations

Conditions: Prevention of Rejection in Kidney Transplant

Learn More ›

Post-Operative Urinary Retention on Revision Knee Arthroplasty: the Role of Intrathecal Morphine

NCT07050277

Recruiting

Revision total knee arthroplasty (rTKA) is a frequently performed procedure. Adequate pain management is an important feature, especially for fast-track and Enhanced Recovery After Surgery (ERAS) programs. The multimodal approach, including single shot or continuous nerve blocks with catheters and spinal or epidural morphine, is a stablished strategy. Although the administration of intrathecal morphine (IM) has been shown to significantly reduce pain scores, it is not free of adverse effects. Po... Read More

Gender:

ALL

Ages:

21 years and above

Trial Updated:

06/25/2025

Locations: Mount Sinai Hospital, Toronto, Ontario

Conditions: Arthroplasties, Knee Replacement, Nerve Block, Urinary Retention Postoperative, Anesthesia, Spinal

Learn More ›

Datopotamab Deruxtecan (Dato-DXd) and Pembrolizumab With or Without Platinum Chemotherapy in 1L Non-Small Cell Lung Cancer (TROPION-Lung07)

NCT05555732

Recruiting

This study is designed to assess the efficacy and safety of datopotamab deruxtecan (Dato-DXd) in combination with pembrolizumab versus pembrolizumab in combination with pemetrexed and platinum chemotherapy in participants with no prior therapy for advanced or metastatic non-squamous non-small cell lung cancer (NSCLC).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/25/2025

Locations: Southern Cancer Center Pc, Daphne, Alabama +246 locations

Southern Cancer Center Pc, Daphne, Alabama

Ironwood Cancer and Research Centers, Chandler, Arizona

Arizona Oncology Associates, Pc - Nahoa, Prescott Valley, Arizona

Hoag Memorial Hospital Prebyterian, Newport Beach, California

Compassionate Cancer Care Medical Group, Riverside, California

Sansum Clinic, Santa Barbara, California

Ronald Reagan UCLA Medical Center, Santa Monica, California

UCHealth Memorial Hospital, Colorado Springs, Colorado

Florida Cancer Specialists - South, Fort Myers, Florida

Cancer Specialist of North Florida, Jacksonville, Florida

Cancer Care Centers of Brevard, Inc., Palm Bay, Florida

Woodlands Medical Specialists, Pa, Pensacola, Florida

Florida Cancer Specialists-North, Saint Petersburg, Florida

Emory University - Winship Cancer Institute Wci, Atlanta, Georgia

Illinois Cancer Specialists, Niles, Illinois

American Oncology Partners of Maryland, Bethesda, Maryland

Maryland Oncology Heamtology P.A., Columbia, Maryland

Beth Israel Deaconess Medical Center, Boston, Massachusetts

Dana Farber Cancer Institute; Inv Drg Svc Pharm, Boston, Massachusetts

Dana Farber Cancer Institute At St. Elizabeth'S Medical Center, Brighton, Massachusetts

Dana Farber Brigham Cancer Center, Foxboro, Massachusetts

Dana Farber At Milford Regional Cancer Center, Milford, Massachusetts

Dana Farber/Bwcc in Affiliation With South Shore Hospital, South Weymouth, Massachusetts

Astera Cancer Care, East Brunswick, New Jersey

Regional Cancer Care Associates LLC, Hackensack, New Jersey

North Shore Hematology Oncology Associates dba NY Cancer and Blood Specialists - Bronx, Bronx, New York

North Shore Hematology Oncology Associates dba NY Cancer and Blood Specialists- New Hyde Park, New Hyde Park, New York

North Shore Hematology Oncology Associates, Patchogue, New York

North Shore Hematology Oncology Associates DBA NY Cancer and Blood Specialists, Port Jefferson Station, New York

Texas Oncology, P.A., McAllen, Texas

Ut Health San Antonio, San Antonio, Texas

Texas Oncology, P.A., Sugar Land, Texas

Texas Oncology-Tyler, Tyler, Texas

Utah Cancer Specialists IHO Corp, Salt Lake City, Utah

Providence Regional Cancer System, Lacey, Washington

VA Puget Sound Health Care System, Seattle, Washington

Instituto Alexander Fleming, Ciudad Autonoma de Buenos Aires, Not set

Fundacion CENIT para la investigacion en Neurociencias, Ciudad Autonoma de Buenos Aire, Not set

Hospital de La Comunidad, Mar del Plata, Not set

Centro de Investigacion Pergamino Sa, Pergamino, Not set

Instituto de Oncologia de Rosario, Rosario, Not set

Sanatorio Parque, Rosario, Not set

Centro Polivalente de Asistencia E Investigacion Clinica Cer San Juan, San Juan, Not set

Centro de Investigaciones Clinicas. Clinica Viedma S.A., Viedma, Not set

CRSA/ St Andrews Hospital, Adelaide, Not set

Flinders Medical Centre (Fmc), Bedford Park, Not set

PSEHOG (Peninsula and South Eastern Haematology and Oncology Group), Frankston, Not set

St George Public Hospital, Kogarah, Not set

Southern Medical Day Care Centre, Wollongong, Not set

Princess Alexandra Hospital, Woolloongabba, Not set

Landeskrankenhaus Feldkirch, Feldkirch, Not set

Klinikum Klagenfurt Pulmologie, Klagenfurt, Not set

Karl Landsteiner Institut Fã¼R Lungenforschung Und Pneumologische Onkologie C/O Klinik Floridsdorf, Vienna, Not set

Az Maria Middelares - Campus Maria Middelares, Gent, Not set

Centre hospitalier Jolimont-Lobbes, Haine Saint-Paul, Not set

Jessa Hospital, Hasselt, Not set

Cliniques Saint Pierre Ottignies (CSPO), Ottignies, Not set

Az Nikolaas, Sint-Niklaas, Not set

Personal Oncologia de Precisao - Cenantron, Belo Horizonte, Not set

Fundaco Universidade de Caxias Do Sul- Instituto de Pesquisas Em Saude Ips-Ucs, Caxias do Sul, Not set

Hospital Erasto Gaertner, Curitiba, Not set

Oncosite - Centro de Pesquisa Clinica Em Oncologia Ltda, Ijui, Not set

Clínica de Neoplasias Litoral Ltda, ItajaĂ-, Not set

Clnica Lacks, Pelotas, Not set

Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Not set

Instituto Nacional de Că'Ncer - Inca, Rio de Janeiro, Not set

Centro de Estudos E Pesquisa de Hematologia E Oncologia - Cepho, Santo Andre, Not set

Instituto de Ensino E Pesquisa Sao Lucas, Sao Paulo, Not set

Instituto Do Cancer Brasil - Unidade Taubate, Taubate, Not set

CHU de Quebec -Universite Laval Hopital de L'Enfant-Jesus, Quebec City, Not set

Centro de Estudios Clinicos Saga Spa, Santiago de Chile, Not set

ONCOVIDA, Santiago, Not set

Orlandi Oncologia, Santiago, Not set

Oncocentro Apys, Vina Del Mar, Not set

Centro de Investigaciones Clinicas Vina Del Mar, ViĂąa Del Mar, Not set

Peking University Cancer Hospital Beijing Cancer Hospital Beijing Institute For Cancer Research, Beijing Sheng, Not set

Peking University Peoples Hospital, Beijing, Not set

Cangzhou Peoples Hospital, Cangzhou, Not set

First Affiliated Hospital of Medical College of Jilin University, Changchun, Not set

Jilin Cancer Hospital, Changchun, Not set

Hunan Cancer Hospital, Changsha, Not set

University of Electronic Science Technology of China UESTC - Sichuan Cancer Hospital Institute SIC, Chengdu, Not set

Chongqing University Cancer Hospital, Chongqing, Not set

Fujian Medical University - Union Hospital Foochow Christian Union Hospital, Fuzhou, Not set

The First Affiliated Hospital Sun Yat-Sen University, Guangzhou, Not set

Affiliated Cancer Hospital and Insititute of Guangzhou Medical University, Guangzhou, Not set

The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Not set

Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Not set

The First Affiliated Hospital of College of Medicine Zhejiang University, Hangzhou, Not set

Harbin Medical University Cancer Hospital, Harbin, Not set

Inner Mongolia Medical University- the Affiliated Hospital, Hohhot, Not set

Jiamusi Cancer Hospital, Jiamusi, Not set

Linyi Cancer Hospital, Linyi, Not set

The First Affiliated Hospital of Nanchang University, Nanchang, Not set

Zhongda Hospital, Southeast University, Nanjing, Not set

Shanghai Chest Hospital, Shanghai, Not set

Fudan University Shanghai Cancer Center, Shanghai, Not set

Liaoning Cancer Hospital & Institute, Shenyang, Not set

Union Hospital of Tongji Medical College Huazhong University of Science and Technology, Wuhan, Not set

The First Affiliate Hospital of Xi'An Jiaotong University, Xi'an, Not set

Xiangyang Central Hospital, Xianyang, Not set

Henan Cancer Hospital, Zhengzhou, Not set

The First Affiliated Hosptial of Xinjiang Medical University, Ürümqi, Not set

FN Brno Klinika Nemoci Plicnich a TBC, Brno, Not set

Fakultni nemocnice Olomouc FNOL, Olomouc, Not set

Sainte-Catherine Institut du Cancer Avignon-Provence, Avignon, Not set

Hopital Jean Minjoz - CHU de Besancon, Besancon, Not set

Chu de Bordeaux - Hopital Saint Andre, Bordeaux, Not set

Centre Hospitalier Universitaire, CHU, de Poitiers, France, Not set

Hopital Lyon Sud, Lyon, Not set

Centre Leon Berard, Lyon, Not set

Aphm - Hopital Nord, Marseille Cedex 20, Not set

Institut Paoli Calmettes, Marseille, Not set

Chu de Montpellier, Montpellier Cedex 5, Not set

Chu de Nantes, Nantes, Not set

Hopital Prive Du Confluent, Nantes, Not set

Institut Curie, Paris Cedex 05, Not set

Tenon Hospital, Paris, Not set

CHU de Rennes - Hopital Pontchaillou, Rennes, Not set

Hôpital Foch, Suresnes, Not set

Evangelische Lungenklinik Berlin, Berlin, Not set

Klinikum Chemnitz, Chemnitz, Not set

Universitaetsklinikum Essen, Essen, Not set

Klinikum Esslingen Gmbh, Esslingen, Not set

Universitaetsklinikum Freiburg, Freiburg, Not set

University Hospital Giessen, ZIM IV, Giessen, Not set

External pharmacy Fortuna Herstellung GmbH of main site Universitaetsmedizin Mannheim, Mannheim, Not set

University Hospital Mă Nster, Muenster, Not set

Ludwig-Maximilians University Hospital of Munich, Munich, Not set

Sotiria General Hospital of Chest Diseases, Athens, Not set

Metropolitan Hospital - Athens, Athens, Not set

University General Hospital of Heraklion, Heraklion, Not set

University Hospital of Ioannina Uhi, Ioannina, Not set

Metropolitan Hospital, Neo Faliro, Not set

Olympion Hospital, Patras, Not set

Euromedica General Clinic of Thessaloniki, Thessaloniki, Not set

St. Luke's Hospital, Thessaloniki, Not set

Bioclinic Thessaloniki (Galinos Clinic), Thessalonki, Not set

Tuen Mun Hospital, Hong Kong, Not set

Prince of Wales Hospital / The Chinese University of Hong Kong, Hong Kong, Not set

Queen Mary Hospital, Pok Fu Lam, Not set

National Koranyi Institute For Pulmonology, Budapest, Not set

Veszprem Megyei Tudogyogyintezet Farkasgyepu, Farkasgyepu, Not set

Bkmk Hospital, KecskemĂŠt, Not set

Fejer Megyei Szent Gyorgy Korhaz Pulmonologiai Osztaly, Szekesfehervar, Not set

Hetenyi G Korhaz, Onkologiai Kozpont, Szolnok, Not set

Reformatus Pulmonologiai Centrum, Torokbalint, Not set

Istituto Di Candiolo Irccs, Candiolo, Not set

Ospedale San Luca, Lucca, Not set

Azienda Ospedaliero - Universitaria San Luigi Gonzaga, Orbassano, Not set

IFO Regina Elena, Rome, Not set

Ospedale S. Maria Della Misericordia, Udine, Not set

Asst Sette Laghi, Varese, Not set

Azienda Ospedaliera Universitaria Integrata Verona Ospedale Borgo Roma Crc - Centro Ricerche Clinich, Verona, Not set

NHO Shikoku Cancer Center, Ehime, Not set

Kurume University Hospital, Fukoka, Not set

Kyushu Cancer Center, Fukuoka, Not set

Kyushu University Hospital, Fukuoka, Not set

Teine Keijinkai Hospital, Hokkaido, Not set

Hyogo Medical University Hospital, Hyogo, Not set

Kanazawa University Hospital, Ishikawa, Not set

Kanagawa Cancer Center, Kanagawa, Not set

Kitasato University hospital, Kanagawa, Not set

Social Welfare Organization Saiseikai Imperial Gift Foundation, Inc. Saiseikai Kumamoto Hospital, Kumamoto, Not set

University Hospital Kyoto Prefectual University of Medicine, Kyoto, Not set

Matsusaka Municipal Hospital, Mie, Not set

Sendai Kousei Hospital, Miyagi, Not set

Niigata Cancer Center Hospital, Niigata, Not set

Osaka International Cancer Institute, Osaka, Not set

Osaka Toneyama Medical Center, Osaka, Not set

Kansai Medical University Hospital, Osaka, Not set

NHO Kinki-Chuo Chest Medical Center, Osaka, Not set

Dokkyo Medical University Hospital, Tochigi, Not set

Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Not set

Juntendo University Hospital, Tokyo, Not set

The Cancer Institute Hospital of JFCR, Tokyo, Not set

Toho University Omori Medical Center, Tokyo, Not set

Iwakuni Clinical Center, Yamaguchi, Not set

Yamaguchi-Ube Medical Center, Yamaguchi, Not set

Yamanashi Prefectural Central Hospital, Yamanashi, Not set

Chungbuk National University Hospital, Cheongjusi, Not set

Kyungpook National University Chilgok Hospital, Daegu, Not set

Samsung Medical Center, Gangnam-Gu, Not set

National Cancer Center, Goyang-si, Not set

Gyeongsang National University Hospital, Jinju-si Gyeongsangnam-do, Not set

Seoul National University Bundang Hospital, Seongnam-si, Not set

Asan Medical Center, Seoul, Not set

Yonsei University Health System - Severance Hospital, Seoul, Not set

The Catholic Univ. of Korea, Seoul St. Marys Hospital, Seoul, Not set

Cryptex Investigacion Clinica Sa de Cv, Cuauhtemoc, Not set

Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Not set

Instituto Nacional de Cancerologia, Mexico City, Not set

Centro de Investigacion Clinica de Oaxaca CICLO, Oaxaca, Not set

Amphia Ziekenhuis, Breda, Not set

Leiden University Medical Center, Leiden, Not set

Jeroen Bosch Ziekenhuis Jbz, s-Hertogenbosch, Not set

II Klinika Chorob Pluc i Gruzlicy, Bialystok, Not set

Centrum Terapii Wspolczesnej, Lodz, Not set

Instytut Centrum Zdrowia Matki Polki (Iczmp), Lodz, Not set

SPSK4, Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie, Lublin, Not set

Med Polonia Sp. Z O.O., Poznan, Not set

Maria Sklodowska-Curie National Research Institute of Oncology, Warszawa, Not set

Fundacao Champalimaud, Lisbon, Not set

IPO Porto Francisco Gentil, E.P.E., Porto, Not set

Institute of Oncology Prof. Dr. Ion Chiricuta, Cluj- Napoca, Not set

Onco Clinic Consult Sa, Craiova, Not set

Centrul de Oncologie Sfantu Nectarie, Craiova, Not set

SC Oncomed SRL, Jud Timis, Not set

Oncocenter Oncologie Clinica S.R.L, Timisoara, Not set

Vall Hebron University Hospital, Barcelona, Not set

Hospital Clinic I Provincial de Barcelona, Barcelona, Not set

Hospital Universitario Arnau de Vilanova, Lleida, Not set

Hospital General Universitario Gregorio Marañon, Madrid, Not set

Hospital Clinico San Carlos, Madrid, Not set

Hospital Universitario Fundacion Jimenez Diaz, Madrid, Not set

Hospital Regional Universitario Malaga, Malaga, Not set

CHUO, Ourense, Not set

Hosp Univ Virgen Macarena, Sevilla, Not set

Hospital Universitario Virgen de Valme, Sevilla, Not set

Hospital Universitario y Politecnico de La Fe, Valenica, Not set

Hospital Universitario Miguel Servet, Zaragoza, Not set

Kantonsspital Baselland, Liestal, Not set

Kantonsspital St. Gallen, St. Gallen, Not set

Spital Sts Ag, Thun, Not set

Changhua Christian Hospital, Changhua, Not set

China Medical University Hospital, Hsia, Not set

Taichung Veterans General Hospital, Taichung, Not set

National Cheng Kung University Hospital, Tainan, Not set

National Taiwan University Hospital, Taipei, Not set

Koo Foundation Sun Yat-Sen Cancer Center, Taipei, Not set

Taipei Veterans General Hospital, Taipei, Not set

Tri-Service General Hospital, Taipei, Not set

Linkou Chang Gung Memorial Hospital, Taoyuan, Not set

Faculty of Medicine Chulalongkorn University, Bangkok, Not set

Ramathibodi Hospital, Bangkok, Not set

Siriraj Hospital, Bangkok, Not set

Chiang Mai University CMU - Maharaj Nakhon Chiang Mai Hospital Nakorn Chiang Mai Hospital, Chiang Mai, Not set

Prince of Songkla University PSU - Faculty of Medicine, Hat Yai, Not set

Khon Kaen University - Faculty of Medicine-Srinagarind Hospital, Mueang Nonthaburi, Not set

Baskent University, Adana, Not set

Ankara Bilkent City Hospital, Ankara, Not set

Akdeniz University Hospital, Antalya, Not set

Medipol Mega University Hospital, Bağcılar, Not set

Memorial Ankara Hospital, Cankaya/Ankara, Not set

Istanbul Medeniyet University Medical Faculty, Istanbul, Not set

Adana Acibadem Hospital, Seyhan, Not set

Barts Health NHS Trust, London, Not set

Conditions: Metastatic Non Small Cell Lung Cancer

Learn More ›

Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

NCT04614103

Recruiting

This is a prospective, open-label, multi-cohort, non-randomized, multicenter phase 2 study evaluating LN-145 in patients with metastatic non-small-cell lung cancer

Gender:

ALL

Ages:

Between 18 years and 70 years

Trial Updated:

06/25/2025

Locations: City of Hope, Duarte, California +63 locations

City of Hope, Duarte, California

UC San Diego Moores Cancer Center, La Jolla, California

University of Southern California, Los Angeles, California

Christiana Care Health System, Newark, Delaware

University of Florida Health Cancer Center, Gainesville, Florida

Sylvester Comprehensive Cancer Center, Miami, Florida

AdventHealth Cancer Institute, Orlando, Florida

H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida

Augusta University, Augusta, Georgia

Rush University Medical Center, Chicago, Illinois

University of Illinois Hospital & Health Sciences System, Chicago, Illinois

Advocate Aurora Health, Park Ridge, Illinois

University of Louisville, Louisville, Kentucky

University of Maryland, Baltimore, Maryland

Dana Farber Cancer Institute, Boston, Massachusetts

Karmanos Cancer Institute, Detroit, Michigan

Henry Ford Health System, Detroit, Michigan

University of Minnesota, Minneapolis, Minnesota

University of Nebraska Medical Center, Omaha, Nebraska

MD Anderson Cooper, Camden, New Jersey

Roswell Park Cancer Institute, Buffalo, New York

New York University Langone Medical Center, New York, New York

Icahn School of Medicine at Mount Sinai, New York, New York

Memorial Sloan Kettering Cancer Center, New York, New York

University of Rochester Medical Center, Rochester, New York

University of North Carolina, Chapel Hill, North Carolina

Novant Health - Charlotte, Charlotte, North Carolina

Novant Health - Winston-Salem, Winston-Salem, North Carolina

Atrium Health Wake Forest University Health Sciences, Winston-Salem, North Carolina

Sanford Roger Maris Cancer Center, Fargo, North Dakota

University of Cincinnati Medical Center, Cincinnati, Ohio

Ohio State University Comprehensive Cancer Center, Columbus, Ohio

University of Oklahoma, Oklahoma City, Oklahoma

Oregon Health and Science University, Portland, Oregon

Allegheny General Hospital, Natrona Heights, Pennsylvania

Fox Chase Cancer Center, Philadelphia, Pennsylvania

Sanford Cancer Center, Sioux Falls, South Dakota

Avera Medical Group Cancer Institute, Sioux Falls, South Dakota

University of Tennessee Medical Center, Knoxville, Tennessee

Baptist Cancer Center, Memphis, Tennessee

Texas Oncology-Baylor Charles A. Sammons Cancer Center, Dallas, Texas

Houston Methodist, Houston, Texas

VCU Medical Center (Virginia Commonwealth University), Richmond, Virginia

Seattle Cancer Care Alliance, Seattle, Washington

St. Vincent's Hospital, Darlinghurst, New South Wales

Westmead Hospital, Westmead, New South Wales

Hollywood Private Hospital Ramsay, Nedlands, Western Australia

Princess Margaret Cancer Centre, Toronto, Ontario

Centre Hospitalier de l'Universite de Montreal (CHUM), Montréal, Not set

Universitätsklinikum Bonn, Bonn, Not set

Universitätsklinikum Carl Gustav Carus, MK I, Dresden, Not set

Universitätsklinikum Mannheim, Mannheim, Not set

Samsung Medical Center, Seoul, Gangnam-gu

Gachon Unversity Gil Medical Center, Incheon, Not set

Severance Hospital, Yonsei University, Seoul, Not set

Het Nederlands Kanker Instituut Antoni Van Leeuwenhoek Ziekenhuis, Amsterdam, Not set

National Cancer Centre Singapore, Singapore, Not set

Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Vaud

University Hospital of Zurich/ Universitätsspital Zürich, Zürich, Not set

Royal Marsden Hospital, Chelsea, England

Sarah Cannon Research Institute, London, England

University College London, London, England

The Christie NHS Foundation Trust, Manchester, England

Guy's Hospital, London, Not set

Conditions: Metastatic Non Small Cell Lung Cancer

Learn More ›

Durvalumab and Tremelimumab in Combination With Propranolol and Chemotherapy for Treatment of Advanced Hepatopancreabiliary Tumors (BLOCKED)

NCT05451043

Recruiting

A single-arm, interventional study combining Immunotherapy and propranolol with/without chemotherapy and propranolol 1. Pancreatic Cancer Durvalumab will be administered once every 4 weeks, in combination with gemcitabine + nab-paclitaxel (day 1/8/15) and continuous propranolol. Tremelimumab will be given on day 1 of cycle 1, which may be repeated at the time of progression in eligible patients. 2. HCC Durvalumab will be administered once every 4 weeks in combination with continuous propranolol... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/24/2025

Locations: Cross Cancer Institute, Edmonton, Alberta

Conditions: Pancreatic Cancer, Hepatocellular Cancer, Biliary Tract Cancer, Cholangiocarcinoma

Learn More ›

SBRT of Metastases Following Neo-adjuvant Treatment for Colorectal Cancer With Synchronous Liver Metastases

NCT05775146

Recruiting

The purpose of this study is to prospectively evaluate the feasibility of SBRT for the management of synchronous oligo metastatic liver metastases from colorectal cancers.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/24/2025

Locations: Cross Cancer Institute, Edmonton, Alberta

Conditions: Colorectal Cancer, Liver Metastasis Colon Cancer

Learn More ›

Tamoxifen Versus Etoposide After First Recurrence in GBM Patients

NCT04765098

Recruiting

The investigator propose a single-center randomized phase II controlled study designed to compare the management of first recurrence of GBM using etoposide versus tamoxifen.

Gender:

ALL

Ages:

Between 18 years and 65 years

Trial Updated:

06/24/2025

Locations: Cross Cancer Institute, Edmonton, Alberta

Conditions: Glioblastoma Multiforme

Learn More ›