All Clinical Trials in Canada

A listing of 3905 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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Pasteurized Donor Human Milk for HIV-Exposed Infants: A Pilot Study

NCT06955715

Recruiting

Pasteurized Donor Human Milk (PDHM) is recognized as providing vital immunological and nutritional benefits to vulnerable infants. Although PDHM is widely used in neonatal intensive care units (NICUs) to prevent infections (necrotizing enterocolitis) and improve infant health outcomes, its use for other populations, such as HIV-exposed infants, has been minimal. Pasteurized donor human milk is included in the 2023 Canadian Paediatric Society clinical consensus as a potential way to provide HIV-exposed infants some of the immunological benefits of human milk in a safe manner, as opposed to exclusive formula feeding (which is currently considered the gold standard for HIV-exposed infants). These new consensus guidelines also include recommendations to support those who wish to breastfeed using a harm reduction approach (e.g., increased viral load monitoring by peds infectious diseases), given the low risk of transmission in those adhering to antiretroviral medications. However, mixed feeding (e.g., breastfeeding and provision of infant formula) is not recommended, due to the potential for micro abrasions in the gastrointestinal epithelium as a result of the protein size in infant formula (which is larger and more abrasive than in human milk), which may increase the risk of HIV transmission if the HIV virus is present in breastmilk. As such, donor milk also presents a possible solution to support those who choose to breastfeed, but who may require a temporary supplement for whatever reason (e.g., nipple cracks, mastitis, etc.), as donor milk is human milk, thus has the same size of proteins and does not pose the same risk as infant formula in damaging the epithelial layer in the gut. Overall, major obstacles remain that prevent newborns outside of the NICU from regularly having access to donor human milk. These obstacles are illustrated by the high cost of donor milk, which is not covered by government programs, and the lack of information about the clinical benefits (for both those who choose to breastfeed or formula feed), acceptability of caregivers for this feeding option, and feasibility of providing donor human milk outside of a hospital setting. The investigators aim to determine whether giving PDHM to infants exposed to HIV is a practical possibility and learn from caregivers about any challenges associated with this feeding option. The results of this study will guide future research and a potential provincial initiative to expand access to PDHM for this population. Read Less

Gender:

ALL

Ages:

15 years and above

Trial Updated:

06/18/2025

Locations: University of Saskatchewan, Saskatoon, Saskatchewan

Conditions: HIV, Pregnancy, Breastfeeding, Infant Feeding Practices

Learn More ›

DAY101 vs. Standard of Care Chemotherapy in Pediatric Participants With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2)

NCT05566795

Recruiting

This is a 2-arm, randomized, open-label, multicenter, global, Phase 3 trial to evaluate the efficacy, safety, and tolerability of tovorafenib monotherapy versus standard of care (SoC) chemotherapy in participants with pediatric low-grade glioma (LGG) harboring an activating rapidly accelerated fibrosarcoma (RAF) alteration requiring first-line systemic therapy.

Gender:

ALL

Ages:

25 years and below

Trial Updated:

06/18/2025

Locations: Children's of Alabama, Birmingham, Alabama +122 locations

Children's of Alabama, Birmingham, Alabama

Phoenix Children's Hospital, Phoenix, Arizona

Children's Hospital Los Angeles, Los Angeles, California

Children's Hospital of Orange County Main Campus - Orange, Orange, California

UCSF Benioff Children's Hospital, San Francisco, California

Children's Hospital Colorado, Aurora, Colorado

Connecticut Children's Medical Center, Hartford, Connecticut

Children's National Medical Center, Washington, District of Columbia

University of Florida Health, Gainesville, Florida

Arnold Palmer Hospital for Children, Orlando, Florida

Johns Hopkins All Children's Hospital, St. Petersburg, Florida

Children's Healthcare of Atlanta, Atlanta, Georgia

Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois

Riley Hospital for Children at Indiana University Health, Indianapolis, Indiana

Maine Children's Cancer Program, Scarborough, Maine

Dana-Farber Cancer Institute, Boston, Massachusetts

University of Michigan - - C.S. Mott Children's Hospital, Ann Arbor, Michigan

Children's Minnesota, Minneapolis, Minnesota

St. Louis Children's Hospital, Saint Louis, Missouri

University of Nebraska Medical Center, Omaha, Nebraska

New York University Langone Health, New York, New York

University of Rochester, Rochester, New York

Duke Cancer Institute, Durham, North Carolina

Cleveland Clinic Main Campus, Cleveland, Ohio

University of Texas Southwestern Medical Center, Dallas, Texas

Texas Children's Hospital, Houston, Texas

Seattle Children's Hospital, Seattle, Washington

University of Wisconsin - Madison, Madison, Wisconsin

Children's Health Queensland Hospital and Health Service, South Brisbane, Queensland

Perth Children's Hospital, Nedlands, Not set

Women's and Children's Health Network, North Adelaide, Not set

The Royal Children's Hospital - Children's Cancer Centre, Parkville, Not set

Sydney Children's Hospital - Randwick, Randwick, Not set

Children's Hospital at Westmead, Westmead, Not set

Medizinische Universität Innsbruck, Innsbruck, Tirol

Medizinische Universität Wien, Wien, Not set

Cliniques Universitaires Saint-Luc, Brussel, Not set

Universitair Ziekenhuis Gent, Ghent, Not set

Universitair Ziekenhuis Leuven - Campus Gasthuisberg, Leuven, Not set

Grupo de Apoio ao Adolescente e à Criança com Câncer (GRAACC), São Paulo, Not set

Alberta Children's Hospital, Calgary, Alberta

Stollery Children's Hospital, Edmonton, Alberta

British Columbia Children's Hospital, Vancouver, British Columbia

McMaster Children's Hospital, Hamilton, Ontario

Children's Hospital of Eastern Ontario, Ottawa, Ontario

CHU Sainte-Justine, Montréal, Quebec

The Montreal Children's Hospital, Montréal, Quebec

Centre Hospitalier de l'Université Laval et Centre Mère-Enfant Soleil, Québec, Not set

SickKids - The Hospital for Sick Children, Toronto, Not set

Fakultní Nemocnice Brno - D?tská Nemocnice, Brno, Not set

Motol University Hospital, Prague, Not set

Aarhus Universitetshospital, Aarhus, Midtjylland

Rigshospitalet, Copenhagen, Not set

Helsingin yliopistollinen sairaala (HUS), Helsinki, Not set

Tampereen Yliopistollinen Sairaala, Tampere, Not set

Centre de Lutte contre le Cancer - Centre Oscar Lambret, Lille, Not set

Centre Léon Bérard, Lyon, Not set

Hôpital de la Timone, Marseille, Not set

Institut Curie, Paris, Not set

Gustave Roussy, Villejuif, Not set

Universitätsklinikum Freiburg, Freiburg, Baden-Württemberg

Universitätsklinikum Augsburg, Augsburg, Bayern

Universitätsklinikum Erlangen, Erlangen, Bayern

Universitätsklinikum Würzburg, Würzburg, Bayern

Universitätsklinikum Frankfurt, Frankfurt, Hessen

Medizinische Hochschule Hannover, Hannover, Niedersachsen

Universitaetsklinikum Essen, Essen, Nordrhein-Westfalen

Universitätsklinikum Leipzig, Leipzig, Sachsen

Charité Universitätsmedizin Berlin, Berlin, Not set

Evangelische Klinikum Bethel (EvKB), Bielefeld, Not set

Universitätsklinikum Hamburg-Eppendorf, Hamburg, Not set

Universitätsklinikum Heidelberg, Heidelberg, Not set

Universitätsklinikum Tübingen, Tübingen, Not set

Aghia Sofia General Children's Hospital, Athens, Not set

Athens General Children's Hospital, Athens, Not set

Semmelweis Egyetem Tűzoltó utcai II. Sz. Gyermekgyógyászati Kliniká, Budapest, Not set

Children's Health Ireland at Crumlin, Crumlin, Dublin

Schneider Children's Medical Center of Israel, Petah tikva, Not set

The Edmond and Lily Safra Children's Hospital, Ramat Gan, Not set

Fondazione IRCCS - Istituto Nazionale dei Tumori, Milano, Milan

Ospedale Pediatrico Bambino Gesù, Roma, Rome

Ospedale Infantile Regina Margherita, Torino, Turin

Azienda Universitaria Ospedaliera Consorziale - Policlinico di Bari, Bari, Not set

Istituto Giannina Gaslini, Genova, Not set

Azienda Ospedaliera di Rilievo Nazional Santobono Pausilipon, Napoli, Not set

Azienda Ospedale Università di Padova, Padova, Not set

Azienda Sanitaria Universitaria Friuli Centrale - P.O. Santa Maria della Misericordia, Udine, Not set

King Hussein Cancer Foundation - King Hussein Cancer Center, Amman, Muhafazat al-Asima

Seoul National University Hospital, Seoul, Not set

Severance Hospital, Seoul, Not set

Prinses Maxima Centrum Kinderoncologie, Utrecht, Not set

Starship Paediatric Blood & Cancer Center, Grafton, Not set

Universitetssykehuset Nord-Norge - Tromsø, Tromsø, Troms

Oslo Universitetssykehus, Oslo, Not set

SingHealth Group - KK Women's and Children's Hospital, Singapore, Not set

Univerzitetni Klinini Center Ljubljana, Ljubljana, Not set

Hospital Universitario Cruces, Barakaldo, Not set

Hospital Universitari Vall d'Hebrón, Barcelona, Not set

Hospital Sant Joan de Déu Barcelona, Barcelona, Not set

Hospital Infantil Universitario Niño Jesús, Madrid, Not set

Hospital Universitario La Paz, Madrid, Not set

Hospital Universitario Virgen del Rocío, Sevilla, Not set

Hospital Universitari i Politècnic La Fe, Valencia, Not set

Drottning Silvias barn- och ungdomssjukhus, Göteborg, Not set

Skånes Universitetssjukhus - Lund, Lund, Not set

Astrid Lindgrens Barnsjukhus Solna, Stockholm, Not set

Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Not set

Universitaets - Kinderspital Zürich, Zurich, Not set

Taipei Medical University Hospital, Taipei, Not set

Chang Gung Memorial Hospital - Linkou Branch, Taoyuan, Not set

Birmingham Women's and Children's NHS Foundation Trust, Birmingham, England

Leeds Teaching Hospital NHS Trust, Leeds, England

Alder Hey Children's NHS Foundation Trust, Liverpool, England

Manchester University NHS Foundation Trust, Manchester, England

The Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, England

Great Ormond Street Hospital for Children, Oxford, England

University Hospital Southampton NHS Foundation Trust, Southampton, Hampshire

Royal Belfast Hospital for Sick Children, Belfast, Northern Ireland

NHS Greater Glasgow and Clyde, Glasgow, Scotland

Sheffield Children's Hospital, Sheffield, South Yorkshire

The Royal Marsden NHS Foundation Trust, Sutton, Surrey

University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, Not set

Cambridge University Hospitals NHS Foundation Trust, Cambridge, Not set

Conditions: Low-grade Glioma, Rapidly Accelerated Fibrosarcoma (RAF) Altered Glioma, Pediatric Low-grade Glioma

Learn More ›

International Rare Histiocytic Disorders Registry (IRHDR)

NCT02285582

Recruiting

The rare histiocytic disorders (RHDs) are characterized by the infiltration of one or more organs by non-LCH histiocytes. They can range from localized disease that resolves spontaneously, to progressive disseminated forms that can be sometimes life-threatening. Since they are extremely rare, there is limited understanding of their causes and best treatment options. Physicians, patients and parents of children with RHDs frequently consult members of the Histiocyte Society regarding the best mana... Read More

Gender:

ALL

Ages:

All

Trial Updated:

06/18/2025

Locations: The University of Alabama at Birmingham, Birmingham, Alabama +14 locations

Conditions: Rare Histiocytic Disorders (RHDs), Erdheim-Chester Disease (ECD), Rosai-Dorfman Disease (RDD), Xanthogranuloma Family (XG), Indeterminate Dendritic Cell Histiocytosis, Malignant Histiocytic Neoplasm (MHN), ALK-positive Histiocytosis, Mixed Histiocytosis (MXH), Multicentric Reticulohistiocytoma (MRH), Necrobiotic Xanthogranuloma (NX)

Learn More ›

A Study to Evaluate Zanubrutinib and Tislelizumab in Progressive Lymphoma Post CAR-T

NCT06167785

Recruiting

This is a phase ll study of participants with large B Cell lymphoma previously treated with anti-CD19 Chimeric antigen receptor (CAR-T) therapy. The purpose of the study is to to evaluate the efficacy of zanubrutinib and tislelizumab in patients with progressive lymphoma post anti-CD 19 CAR-T failure.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/18/2025

Locations: University Health Network (UHN), Toronto, Ontario

Conditions: Large B-cell Lymphoma

Learn More ›

Study of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid Tumors

NCT03645928

Recruiting

A prospective, open-label, multi-cohort, non-randomized, multicenter Phase 2 study evaluating adoptive cell therapy (ACT) with TIL \[LN-144/LN-145 (lifileucel)\] in combination with immune checkpoint inhibitors or TIL \[LN-144/LN-145 (lifileucel) and LN-145-S1\] as a single agent therapy.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/18/2025

Locations: University of California, San Diego, La Jolla, California +44 locations

University of California, San Diego, La Jolla, California

University of Southern California, Los Angeles, California

University of California, Los Angeles, Los Angeles, California

University of Colorado, Denver, Colorado

Yale University, New Haven, Connecticut

Georgetown University Medical Center, Washington, District of Columbia

Mount Sinai Medical Center, Miami Beach, Florida

Orlando Health Cancer Institute, Orlando, Florida

Moffitt Cancer Center, Tampa, Florida

University of Louisville, Louisville, Kentucky

University of Maryland, Baltimore, Maryland

Massachusetts General Hospital, Boston, Massachusetts

Karmanos Cancer Institute, Detroit, Michigan

Henry Ford Health System, Detroit, Michigan

MD Anderson at Cooper, Camden, New Jersey

Morristown Medical Center, Morristown, New Jersey

Columbia University, New York, New York

Memorial Sloan Kettering Cancer Center, New York, New York

University of Cincinnati, Cincinnati, Ohio

Ohio State University, Columbus, Ohio

Avera Cancer Institute, Sioux Falls, South Dakota

Huntsman Cancer Hospital, Salt Lake City, Utah

Fred Hutchinson Cancer Research Center, Seattle, Washington

Medical College of Wisconsin, Milwaukee, Wisconsin

Princess Margaret Cancer Centre, Toronto, Ontario

Centre Léon Berard, Lyon, Not set

Klinikum rechts der Isar der Technischen Universität München, München, Bavaria

Universitätsklinikum Carl Gustav Carus, Dresden, Sachsen

Universitätsklinikum Schleswig-Holstein - Campus Lübeck, Lübeck, Schleswig-Holstein

Laiko General Hospital of Athens, Athens, Attiki

Attikon University General Hospital, Athens, Attiki

Hospital Universitario Marques de Valdecilla, Santander, Cantabria

University Hospital Vall d'Hebron, Barcelona, Not set

ICO l'Hospitalet - Hospital Duran i Reynals, Barcelona, Not set

Hospital General Universitario Gregorio Marañón, Madrid, Not set

Hospital Universitario Fundacion Jimenez Diaz, Madrid, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

Hospital Universitario HM Sanchinarro, Madrid, Not set

Hospital Regional Universitario de Malaga - Hospital General, Málaga, Not set

Universitätsspital Basel, Basel, Not set

Universitaetsspital Bern, Bern, Not set

Centre Hospitalier Universitaire Vaudois, Lausanne, Not set

Guy's Hospital, London, England

The Royal Marsden NHS Foundation Trust, London, England

Bristol Haematology and Oncology Centre, Bristol, Not set

Conditions: Metastatic Melanoma, Squamous Cell Carcinoma of the Head and Neck, Non-small Cell Lung Cancer

Learn More ›

JoLT-Ca Sublobar Resection (SR) Versus Stereotactic Ablative Radiotherapy (SAbR) for Lung Cancer

NCT02468024

Recruiting

To Determine if SAbR improves survival over SR in High Risk Operable Stage I NSCLC

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/18/2025

Locations: UCSD, La Jolla, California +49 locations

UCSD, La Jolla, California

University of Colorado/Memorial, Aurora, Colorado

Penrose Cancer Center, Colorado Springs, Colorado

Boca Raton Regional Hospital, Boca Raton, Florida

Curtis and Elizabeth Anderson Cancer, Savannah, Georgia

University of Iowa, Iowa City, Iowa

University of Kansas Medical Center, Kansas City, Kansas

University of Kentucky Health Care, Lexington, Kentucky

University of Louisville Physicians, Louisville, Kentucky

Ochsner Medical Center, New Orleans, Louisiana

Luminis Health Research Institute, Annapolis, Maryland

University of Maryland Medical Center, Baltimore, Maryland

Boston Medical Center, Boston, Massachusetts

Henry Ford Health System, Detroit, Michigan

Beaumont, Royal Oak, Michigan

Mayo Clinic Rochester, Rochester, Minnesota

Meridian Health System, Neptune, New Jersey

New York University Langone Medical Center, New York, New York

SUNY - Upsate Medical Centre, Syracuse, New York

University of North Carolina, Chapel Hill, North Carolina

Wake Forest Baptist Health, Winston-Salem, North Carolina

University of Cincinnati, Cincinnati, Ohio

Case Western (University Hospitals Case Medical Center), Cleveland, Ohio

Cleveland Clinic, Cleveland, Ohio

Ohio State University Wexner Medical Center, Columbus, Ohio

Providence Health & Services/Oregon Clinic, Portland, Oregon

Thomas Jefferson University, Philadelphia, Pennsylvania

UPMC Health System, Pittsburgh, Pennsylvania

Allegheny, Pittsburg, Pennsylvania

Mount Nittany, State College, Pennsylvania

Lifespan Oncology Clinical Research, Providence, Rhode Island

University of Tennessee Health Science Center, Memphis, Tennessee

Cardiothoracic and Vascular Surgeons, Austin, Texas

University of Texas Southwestern Medical Center, Dallas, Texas

Intermountain Medical Center, Salt Lake City, Utah

University of Virginia Health System, Charlottesville, Virginia

Inova Fairfax Medical Campus, Falls Church, Virginia

Swedish Cancer Institute, Seattle, Washington

Medical College of Wisconsin, Milwaukee, Wisconsin

Clement Zablocki VA Medical Center, Milwaukee, Wisconsin

St. Vincent's Hospital Melbourne, Fitzroy, Melbourne

St. Vincent's/Peter Mac, Fitzroy, Victoria

Barwon Health - Uni Hospital Geelong, Geelong, Victoria

Lawson Health Science Center, London, Ontario, Canada

Ottawa Hospital Cancer Center, Ottawa, Ontario

UHN-Toronto, Toronto, Ontario

CHUM, Montréal, Quebec

Trillium Health Partners, Mississauga, Not set

Sunnybrook Health Sciences Centre, Toronto, Not set

The James Cook University Hospital, Middlesbrough, Not set

Conditions: Non-Small Cell Lung Cancer

Learn More ›

Predicting the Quality of Response to Specific Treatments in Patients With cGVHD, PQRST Study

NCT04431479

Recruiting

This trial collects clinical data and blood samples to predict the quality of response to specific treatments in patients with chronic graft-versus-host disease (cGVHD) who are about to start a new therapy. Collecting and analyzing clinical data and blood samples from patients with cGVHD before and after treatment initiation may help doctors identify changes that may predict treatment response.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/18/2025

Locations: University of Florida, Gainesville, Florida +9 locations

Conditions: Chronic Graft Versus Host Disease

Learn More ›

Study of PF-07220060 With Letrozole in Adults With HR-positive HER2-negative Breast Cancer Who Have Not Received Anticancer Treatment for Advanced/Metastatic Disease

NCT06760637

Recruiting

The purpose of this study is to determine the safety and efficacy of PF-07220060 with letrozole compared to approved treatments (ie, palbociclib, ribociclib or abemaciclib with letrozole) in people with breast cancer: * HR-positive (breast cancer cells that need estrogen or progesterone to grow) * HER2-negative (cells that have a small amount or none of a protein called HER2 on their surface); * locally advanced (that has spread from where it started to nearby tissue or lymph nodes) or metastat... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/17/2025

Locations: Ironwood Cancer & Research Centers, Chandler, Arizona +254 locations

Ironwood Cancer & Research Centers, Chandler, Arizona

Ironwood Cancer & Research Centers, Gilbert, Arizona

Ironwood Cancer & Research Centers, Glendale, Arizona

Ironwood Cancer & Research Centers, Mesa, Arizona

Ironwood Cancer & Research Centers, Phoenix, Arizona

Ironwood Cancer & Research Centers, Scottsdale, Arizona

Highlands Oncology, Fayetteville, Arkansas

Highlands Oncology, Rogers, Arkansas

Highlands Oncology Group, Springdale, Arkansas

Cancer and Blood Specialty Clinic / Cancer and Blood Research Center, LLC, Los Alamitos, California

Keck Hospital of USC, Los Angeles, California

Los Angeles General Medical Center, Los Angeles, California

Norris Healthcare Center 3 (HC3), Los Angeles, California

USC/Norris Comprehensive Cancer Center, Los Angeles, California

Keck Medicine of USC Norris Oncology/Hematology - Newport Beach Treatment Center, Newport Beach, California

USC Norris Oncology/Hematology - Newport Beach, Newport Beach, California

Keck Medical Center of USC Pasadena, Pasadena, California

Wellness Oncology Hematology, West Hills, California

Intermountain Health St. Joseph Hospital, Denver, Colorado

Saint Joseph Hospital - Cancer Centers of Colorado, Denver, Colorado

Intermountain Health Lutheran Hospital, Golden, Colorado

Lutheran Hospital - Cancer Centers of Colorado, Golden, Colorado

Cancer Centers of Colorado St. Mary's Regional Hospital, Grand Junction, Colorado

Intermountain Health Saint Mary's Regional Hospital, Grand Junction, Colorado

Intermountain Health, Grand Junction, Colorado

MedStar Washington Hospital Center, Washington, District of Columbia

AdventHealth Altamonte Infusion Center, Altamonte Springs, Florida

AdventHealth Altamonte Springs, Altamonte Springs, Florida

AdventHealth Medical Group Altamonte, Altamonte Springs, Florida

Mount Sinai Medical Center, Aventura, Aventura, Florida

Boca Raton Regional Hospital, Boca Raton, Florida

Mount Sinai Comprehensive Cancer Center, Miami Beach, Florida

Mount Sinai Medical Center, Miami Beach, Florida

Mid Florida Hematology and Oncology Center, Orange City, Florida

AdventHealth Orlando, Orlando, Florida

AdventHealth Medical Group Orlando, Orlando, Florida

AdventHealth Orlando Infusion Center, Orlando, Florida

Summit Cancer Care, PC, Savannah, Georgia

St. Luke's Cancer Institute: Boise, Boise, Idaho

St. Luke's Regional Medical Center, Boise, Idaho

St. Luke's Cancer Institute-Fruitland, Fruitland, Idaho

St. Luke's Cancer Institute-Meridian, Meridian, Idaho

St. Lukes Meridian Medical Center, Meridian, Idaho

St. Luke's Cancer Institute-Nampa, Nampa, Idaho

Endeavor Health, Elmhurst, Illinois

Ascension Illinois - Evanston Infusion Center, Evanston, Illinois

Hope and Healing Cancer Services, Hinsdale, Illinois

Endeavor Health, Naperville, Illinois

Hope and Healing Cancer Services, New Lenox, Illinois

Ascension Illinois-Skokie Infusion Center, Skokie, Illinois

Orchard Healthcare Research Inc., Skokie, Illinois

Velocity Clinical Research, Annapolis, Maryland

Mercy Medical Center - Baltimore, Baltimore, Maryland

Brigham and Women's Hospital, Boston, Massachusetts

Beth Israel Deaconess Medical Center, Boston, Massachusetts

Dana-Farber Cancer Institute, Boston, Massachusetts

Dana-Farber Cancer Institute - Chestnut Hill, Newton, Massachusetts

Allina Health Cancer Institute - Mercy Hospital, Coon Rapids, Minnesota

Allina Health Cancer Institute - Abbott Northwestern Hospital, Minneapolis, Minnesota

Allina Health Cancer Institute - United Hospital, Saint Paul, Minnesota

Saint Luke's Cancer Institute, Kansas City, Missouri

Bozeman Health Deaconess Hospital, Bozeman, Montana

Renown Health, Reno, Nevada

Renown Regional Medical Center, Reno, Nevada

Providence Cancer Institute Franz Clinic, Portland, Oregon

Providence Portland Medical Center Investigational Drug Services, Portland, Oregon

Providence Portland Medical Center, Portland, Oregon

Providence Investigational Drug Service - Westside, Portland, Oregon

Providence Oncology and Hematology Care Clinic - Westside, Portland, Oregon

Providence St. Vincent Medical Center, Portland, Oregon

The University of Texas Health Science Center at Tyler dba UT Health East Texas HOPE Cancer Center, Tyler, Texas

The University of Texas Health Science Center at Tyler on behalf of UT Health East Texas HOPE Cancer, Tyler, Texas

Utah Cancer Specialists, Bountiful, Utah

Utah Cancer Specialists, Layton, Utah

Utah Cancer Specialists, Murray, Utah

Utah Cancer Specialists, Ogden, Utah

Utah Cancer Specialists, Orem, Utah

Utah Cancer Specialists, Pleasant Grove, Utah

Utah Cancer Specialists, Provo, Utah

Utah Cancer Specialists, Salt Lake City, Utah

Utah Cancer Specialists, West Jordan, Utah

Utah Cancer Specialists, West Valley City, Utah

Townsville University Hospital, Douglas, Queensland

Princess Alexandra Hospital, Woolloongabba, Queensland

Rosebud Hospital, Capel Sound, Victoria

Frankston Hospital, Frankston, Victoria

Peter MacCallum Cancer Centre, Melbourne, Victoria

Royal Melbourne Hospital, Parkville, Victoria

Grand Hôpital de Charleroi, Gilly, Hainaut

AZ Maria Middelares, Gent, Oost-vlaanderen

UZ Leuven, Leuven, Vlaams-brabant

AZORG Campus Aalst-Moorselbaan, Aalst, Not set

Multiprofile Hospital for Active Treatment Serdika EOOD, Sofia, Sofia (stolitsa)

Complex Oncology Center - Burgas, Burgas, Not set

Multiprofile Hospital for Active Treatment Dr. Tota Venkova AD, Gabrovo, Not set

Specialized Hospital for Active Treatment of Oncology - Haskovo, Haskovo, Not set

Complex Oncology Center - Plovdiv EOOD, Plovdiv, Not set

Complex Oncology Center - Shumen, Shumen, Not set

MHAT for Women's Health Nadezhda, Sofia, Not set

Dr. Everett Chalmers Regional Hospital, Fredericton, New Brunswick

Princess Margaret Cancer Centre, Toronto, Ontario

Cancer Hospital Chinese Academy of Medical Science, Beijing, Beijing

Peking University People's Hospital, Beijing, Beijing

Beijing Cancer hospital, Beijing, Beijing

The First People's Hospital of Foshan, Foshan, Guangdong

Sun Yat-sen University Cancer Center, Guangzhou, Guangdong

Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei

Hunan Cancer Hospital, Changsha, Hunan

Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu

The First Hospital of Jilin University, Changchun, Jilin

The 2nd Affiliated Hospital of Dalian Medical University, Dalian, Liaoning

The First Hospital of China Medical University, Shenyang, Liaoning

The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi

Sir Run Run Shaw Hospital, Hangzhou, Zhejiang

Taizhou Hospital of Zhejiang Province, Linhai, Zhejiang

Fakultni Thomayerova nemocnice, Prague, Praha 4

Fakultni nemocnice v Motole, Praha, Praha 5

Nemocnice AGEL Novy Jicin a.s., Nový Jičín, Not set

Rigshospitalet, Copenhagen, Hovedstaden

Aarhus Universitetshospital, Skejby, Aarhus, Midtjylland

Aalborg Universitetshospital, Syd, Aalborg, Nordjylland

Esbjerg sygehus, Syddansk Universitetshospital, Esbjerg, Syddanmark

Sygehus Soenderjylland, Soenderborg, Syddanmark

Tampereen yliopistollinen sairaala, Tampere, Pirkanmaa

Vaasan Keskussairaala, Vaasa, Pohjanmaa

Helsinki University Hospital - Comprehensive Cancer Center (HYKS - Syöpäkeskus), Helsinki, Uusimaa

Turku University Hospital, Turku, Varsinais-suomi

Institut Bergonié - Centre Régional de Lutte Contre Le Cancer de Bordeaux et Sud Ouest, Bordeaux, Aquitaine

Centre Eugène Marquis Rennes - Centre de Lutte Contre le Cancer, Rennes, Ille-et-vilaine

Centre de Cancérologie du Grand Montpellier, Montpellier, Languedoc-roussillon

Institut de Cancérologie de l'Ouest, Saint Herblain, Loire-atlantique

Institut de Cancérologie de l'Ouest, ANGERS cedex 02, Maine-et-loire

Centre de Lutte Contre le Cancer - Centre Henri Becquerel Normandie Rouen, Rouen, Seine-maritime

CHD Vendee, La Roche-sur-Yon, Vendée

Centre Hospitalier de la Côte Basque, Bayonne, Not set

Henri Mondor Hospital, Créteil, Île-de-france

InVO Institut für Versorgungsforschung in der Onkologie, Koblenz, Rheinland-pfalz

Universitaetsklinikum Carl Gustav Carus Dresden, Dresden, Sachsen

Gemeinschaftspraxis Hämatologie - Onkologie Freiberg-Richter, Jacobasch, Illmer, Wolf, Dresden, Not set

Facharztzentrum Eppendorf, Hamburg, Not set

Agios Savvas Regional Cancer Hospital, Athens, Attikí

Hygeia Hospital, Marousi, Attikí

Aretaieio Hospital, Αθήνα, Attikí

Aretaieio Hospital, Athens, Not set

Heves Vármegyei Markhot Ferenc Oktatókórház és Rendelőintézet, Eger, Heves

Országos Onkológiai Intézet, Budapest, Not set

Rajiv Gandhi Cancer Institute And Research Centre, New Delhi, Delhi

Nirmal Hospital Pvt Ltd., Surat, Gujarat

Artemis hospital, Gurugram, Haryana

Spandana Oncology Centre (SOC), Bangalore, Karnataka

Tata Memorial Hospital, Mumbai, Maharashtra

Apex Wellness Hospital, Nashik, Maharashtra

Deenanath Mangeshkar Hospital & Research Centre, Pune, Maharashtra

Sahyadri Super Speciality Hospital, Pune, Maharashtra

Bhakti Vedanta Hospital and Research Institute, Thane, Maharashtra

Basavatarakam Indo American Cancer Hospital & Research Institute, Hyderabad, Telangana

Apollo Multispeciality Hospitals limited, Kolkata, WEST Bengal

Mater Misericordiae University Hospital, Dublin, Not set

Mater Private Hospital - Dublin, Dublin, Not set

Beaumont Hospital, Dublin, Dublin, Not set

Rabin Medical Center, Petah Tikva, Hamerkaz

Sheba Medical Center, Ramat Gan, Hamerkaz

Rambam Health Care Campus, Haifa, Hatsafon

Sourasky Medical Center, Tel Aviv, Tell Abīb

Hadassah Medical Center, Jerusalem, Yerushalayim

IRCCS - Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", Meldola, Emilia-romagna

Cro-Irccs, Aviano, Friuli-venezia Giulia

Istituto Nazionale Tumori Regina Elena, Rome, Roma

Azienda Ospedaliera Universitaria Careggi, Firenze, Toscana

Istituto Europeo di Oncologia IRCCS, Milano, Not set

Azienda Ospedaliero Universitaria Maggiore della Carità, Novara, Not set

Aichi Cancer Center, Nagoya, Aichi

Nagoya University Hospital, Nagoya, Aichi

Nagoya City University Hospital, Nagoya, Aichi

Gunma Prefectural Cancer Center, Otashi, Gunma

National Hospital Organization Hokkaido Cancer Center, Sapporo, Hokkaido

Kanagawa cancer center, Yokohama, Kanagawa

Kyoto University Hospital, Sakyo-ku, Kyoto

Tohoku University Hospital, Sendai, Miyagi

Osaka University Hospital, Suita, Osaka

Juntendo University Hospital, Bunkyo-ku, Tokyo

National Cancer Center Hospital, Chuo-ku, Tokyo

The Cancer Institute Hospital of JFCR, Koto-ku, Tokyo

Showa University Hospital, Shinagawa, Tokyo

National Center for Global Health and Medicine, Shinjuku City, Tokyo

Chiba Cancer Center, Chiba, Not set

National Hospital Organization Kyushu Cancer Center, Fukuoka, Not set

Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Not set

Kumamoto Shinto General Hospital, Kumamoto, Not set

Okayama University Hospital, Okayama, Not set

National Hospital Organization Osaka National Hospital, Osaka, Not set

Osaka International Cancer Institute, Osaka, Not set

Gachon University Gil Medical Center, Incheon, Incheon-gwangyeoksi [incheon]

Gangnam Severance Hospital, Yonsei University Health System, Gangnam-gu, Seoul-teukbyeolsi [seoul]

Korea University Anam Hospital, Seoul, Seoul-teukbyeolsi [seoul]

Asan Medical Center, Seoul, Seoul-teukbyeolsi [seoul]

Ewha Womans University Mokdong Hospital, Seoul, Seoul-teukbyeolsi [seoul]

Centrum Badań Klinicznych Jagiellońskie Centrum Innowacji sp. z o.o., Kraków, Małopolskie

Pratia MCM Krakow, Kraków, Małopolskie

AIDPORT Sp. z o.o., Skórzewo, Wielkopolskie

Europejskie Centrum Zdrowia Otwock Szpital im.F.Chopina, Otwock, Not set

Instytut MSF Sp zoo, Łódź, Łódzkie

Nemocnica s poliklinikou Stefana Kukuru Michalovce a.s., Michalovce, Košický KRAJ

Nemocnica AGEL Komarno, Komarno, Nitriansky KRAJ

Medeon, s.r.o., Banka, Trnavský KRAJ

Hospital General Universitario de Elche, Elche, Alicante

Hospital Universitari Vall d'Hebron, Barcelona, Barcelona [barcelona]

Institut Català d'Oncologia - L'Hospitalet, Hospitalet, Barcelona [barcelona]

Hospital Clínic de Barcelona, Barcelona, Catalunya [cataluña]

Hospital Jerez de la Frontera, Jerez de la Frontera, Cádiz

Hospital Universitario 12 de Octubre, Madrid, Madrid, Comunidad DE

Hospital Universitario Virgen de la Victoria, Malaga, Málaga

Osi Bilbao-Basurto, Bilbo, PAÍS Vasco

Hospital Universitario San Cecilio, Granada, Not set

Hospital Universitario HM Sanchinarro, Madrid, Not set

Hospital Universitario de Salamanca - Complejo Asistencial Universitario de Salamanca, Salamanca, Not set

Hospital Universitario Virgen Macarena, Sevilla, Not set

Sjukhuset I Gävle, Gävle, Gävleborgs LÄN [se-21]

Södersjukhuset, Stockholm, Stockholms LÄN [se-01]

Akademiska sjukhuset, Uppsala, Uppsala LÄN [se-03]

Västmanlands Sjukhus Västerås, Västerås, Västmanlands LÄN [se-19]

Sahlgrenska Universitetssjukhuset, Gothenburg, Västra Götalands LÄN [se-14]

Lanssjukhuset Ryhov, Jönköping, Not set

Capio Saint Görans Sjukhus, Stockholm, Not set

Sundsvalls Sjukhus, Sundsvall, Not set

Tumor Zentrum Aarau, Aarau, Aargau

Inselspital Bern, Bern, Berne

Kantonsspital Frauenfeld - Spital Thurgau AG, Frauenfeld, Thurgau

Kantonsspital Baden, Baden, Not set

Kantonsspital Graubünden, Chur, Not set

Kantonsspital Münsterlingen - Spital Thurgau AG, Münsterlingen, Not set

Kantonsspital Olten, Olten, Not set

Kantonsspital Winterthur, Winterthur, Not set

National Taiwan University Hospital - Hsinchu branch, Zhu Bei City, Hsinchu

Taichung Veterans General Hospital, Taichung, Not set

National Cheng Kung University Hospital, Tainan, Not set

National Taiwan University Hospital, Taipei, Not set

Mackay Memorial Hospital, Taipei, Not set

Taipei Veterans General Hospital, Taipei, Not set

Koo Foundation Sun Yat-Sen Cancer Center, Taipei, Not set

Chang Gung Medical Foundation-Linkou Branch, Taoyuan, Not set

Medipol Mega Universite Hastanesi, Istanbul, İ̇stanbul

İ.A.Ü VM Medical Park Florya Hastanesi, Istanbul, İ̇stanbul

TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi, Istanbul, İ̇stanbul

Gulhane Egitim Arastirma Hastanesi, Ankara, Not set

Hacettepe Universite Hastaneleri, Ankara, Not set

Memorial Ankara Hastanesi, Ankara, Not set

Gazi University Health Research and Application Center Gazi Hospital, Ankara, Not set

Dicle Üniversitesi, Diyarbakir, Not set

Sakarya Training and Research Hospital, Sakarya, Not set

Imperial College Healthcare NHS Trust, Charing Cross Hospital, London, Hammersmith AND Fulham

Sarah Cannon Research Institute UK, London, London, CITY OF

The Christie NHS Foundation Trust, Manchester, Not set

Conditions: Breast Cancer

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The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)

NCT05427370

Recruiting

The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy (STICH3C) trial is a prospective, unblinded, international multi-center randomized trial of 754 subjects enrolled in approximately 45 centers comparing revascularization by percutaneous coronary intervention (PCI) vs. coronary artery bypass grafting (CABG) in patients with multivessel/left main (LM) coronary artery disease (CAD) and reduced left ventricular ejection fraction (LVEF). The primary objective is to determine whether C... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/17/2025

Locations: Cedars-Sinai, Los Angeles, California +34 locations

Cedars-Sinai, Los Angeles, California

UofL Health, Inc, Louisville, Kentucky

Mayo Clinic, Rochester, Minnesota

University Hospitals Cleveland Medical Center, Cleveland, Ohio

Medical University of Vienna, Vienna, Not set

Heart Institute, Medical School of the University of Sao Paulo_INCOR, São Paulo, Not set

University of Calgary; Libin Cardiovascular Institute, Calgary, Alberta

Mackenzie Health Sciences Center, Edmonton, Alberta

Fraser Health; Royal Columbian Hospital, New Westminster, British Columbia

Providence Health, Vancouver, British Columbia

Queen Elizabeth II Hospital, Halifax, Nova Scotia

Hamilton General Hospital, Hamilton, Ontario

London Health Sciences Center, University Hospital, London, Ontario

Southlake Regional HC, Newmarket, Ontario

Ottawa Heart Institute, Ottawa, Ontario

Sunnybrook Health Sciences Center, Toronto, Ontario

St. Michael's, Toronto, Ontario

Toronto General Hospital, Toronto, Ontario

Center Hospitalier Universitaire de Montreal, Montréal, Quebec

Montreal Heart Institute, Montréal, Quebec

Hospital Sacre-Coeur, Montréal, Quebec

Institut de Cardiologie Quebec (QC) - Laval, Québec, Quebec

Jilin Heart Hospital, Jilin, Changchun

Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, Not set

Clinical Hospital Dubrava, Sušak, Zagreb

University Hospital Dusseldorf, Düsseldorf, Not set

G Kuppuswamy Naidu Memorial Hospital (GKNM), Palayam, Tamil Nadu

European Hospital, Via Portuense, Roma, RM

Instituto Mexicano del Seguro Social (IMSS), Ciudad de México, Not set

Medical University of Silesia, Katowice, Not set

Unidade Local de Saude Lisboa Ocidental (ULSLO), Lisboa, Not set

Dedinje Cardiovascular Institute, Belgrade, Not set

Hospital Clinic de Barcelona (ICCV), Barcelona, L'Eixample

Hospital del Vinalopó, Alicante, Not set

Hospital Universitario de Navarra, Pamplona, Not set

Conditions: Coronary Artery Disease, Heart Failure Systolic

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Outpatient and Intermittent Dosing of Elranatamab in Relapsed/Refractory Multiple Myeloma

NCT06421675

Recruiting

A phase II study of single agent elranatamab in patients with relapsed and/or refractory multiple myeloma (MM) who have previously received at least three classes of therapeutic agents and are refractory to the last line of treatment. The primary objective of this study is to improve the tolerability and safety of elranatamab in patients with relapsed and/or refractory multiple myeloma by evaluating an outpatient and intermittent dosing strategy.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/17/2025

Locations: Arnie Charbonneau Cancer Institute, Calgary, Alberta +5 locations

Conditions: Refractory Multiple Myeloma

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A Study to Learn About the Effectiveness of Etrasimod in People With Ulcerative Colitis

NCT06294925

Recruiting

The purpose of this real world non-interventional study is to learn about the effects of etrasimod as treatment for patients with moderate to severe ulcerative colitis. Patients will be treated according to standard of care and will only be included in the study if etrasimod is the best treatment choice according to the treating physician. Additionally, patients have to be between 18 and 65 years of age and should not have taken etrasimod in the past. All patients will be prescribed etrasimod... Read More

Gender:

ALL

Ages:

Between 18 years and 65 years

Trial Updated:

06/17/2025

Locations: Vancouver Coastal Health, Vancouver, British Columbia +30 locations

Vancouver Coastal Health, Vancouver, British Columbia

Providence Health Care (PHC), Vancouver, British Columbia

Gastroenterologie OpernstraBe, Kassel, Hessen

MVZ Gastroenterologie Aachen, Aachen, Not set

Praxis Heil und Müller, Andernach, Not set

MVZ für Gastroenterologie am Bayerischen Platz, Berlin, Not set

MVZ Dachau, Dachau, Not set

Interdisziplinares Crohn Colitis Centrum, Frankfurt am Main, Not set

Facharztpraxis für Gastroenterologie, Grevenbroich, Not set

Studiengesellschaft BSF UG., Halle (Saale), Not set

Praxis für Gasteroenterologie, Heidelberg, Not set

Evangelisches Krankenhaus Kalk, Koeln, Not set

Praxis für Gasteroenterologie Lübeck, Lübeck, Not set

Klinikum Lüneburg, Lüneburg, Not set

Internistische Praxengemeinschaft Oldenburg, Oldenburg, Not set

Magen-Darm-Zentrum Remscheid, Remscheid, Not set

CED am Rhein, Wesseling, Not set

NHS Greater Glasgow and Clyde, Glasgow, Lanarkshire

Nottingham University Hospitals NHS Trust, Queens Medical Centre, Nottingham, Nottinghamshire

Oxford University Hospitals NHS Foundation Trust, Oxford, Oxfordshire

Western General Hospital, Edinburgh, Scotland

Northern Care Alliance NHS Foundation Trust, Greater Manchester, Crumpsall, Not set

Tunbridge Wells Hospital, Kent, Not set

Barts Health NHS Trust, The Royal London Hospital, London, Not set

St. Mark's Hospital, London, Not set

University College London Hospital, London, Not set

St Thomas' Hospital - Guy's & St Thomas' NHS Foundation Trust, London, Not set

Kings College Hospital, London, Not set

St George's Hospital - St George's Healthcare Nhs Trust, London, Not set

Imperial College Healthcare NHS, London, Not set

Southampton University Hospitals NHS Trust, Southampton, Not set

Conditions: Colitis, Ulcerative

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@neurIST : Intregrated Biomedical Informatics for the Management of Cerebral Aneurysms

NCT05526352

Recruiting

The primary aim of the SwissNeuroFoundation AneurysmDataBase Project is to implement information technology based tools to create and use a holistic reference database specific to intracranial aneurysms (IA). The SwissNeuroFoundation AneurysmDataBase are concerned with generating the data with which to populate this database. The purpose for populating the database are to: * Screen for and evaluate markers of risk for intracranial aneurysm formation and aneurysm rupture. Are considered as mar... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

06/17/2025

Locations: University of California, San Francisco, California +20 locations

Conditions: Intracranial Aneurysm

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