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A listing of 3904 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
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Long-term Safety and Efficacy of ESK-001 in Moderate to Severe Plaque Psoriasis
Recruiting
The objective of the ESK-001-018 long term extension is to evaluate the safety and efficacy of ESK-001 over time. The scientific questions it aims to answer are:
* How safe is taking ESK-001 long-term in people with moderate to severe plaque psoriasis?
* Does taking ESK-001 long-term reduce the severity of people's plaque psoriasis?
Patients will enter the long-term extension study following completion of one of the parent studies (ESK-001-016 or ESK-001-017) and will receive open-label ESK-00... Read More
The objective of the ESK-001-018 long term extension is to evaluate the safety and efficacy of ESK-001 over time. The scientific questions it aims to answer are:
* How safe is taking ESK-001 long-term in people with moderate to severe plaque psoriasis?
* Does taking ESK-001 long-term reduce the severity of people's plaque psoriasis?
Patients will enter the long-term extension study following completion of one of the parent studies (ESK-001-016 or ESK-001-017) and will receive open-label ESK-001 twice daily for 24 weeks. After 24 weeks, the first 200 patients meeting at least PASI-75 clinical response will be randomly assigned to receive ESK-001 or placebo. At any point during this time, the patients losing the initial clinical response may return to the open-label ESK-001 treatment. Patients who complete Week 48 will return to open-label ESK-001 treatment and they will receive ESK-001 until the end of the study or discontinuation. All the remaining patients not meeting the entry criteria for the randomized withdrawal phase will continue to receive open-label ESK-001 for the remainder of the study.
Patients taking part in the study must be men or women aged at least 18 years old and have completed a previous (parent) study of ESK-001 in moderate to severe plaque psoriasis.
Patients must consent and agree to:
* ensure drug daily compliance until end of study or discontinuation.
* visit the clinic for checkups and assessments.
* provide blood and urine samples. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/19/2025
Locations: Total Dermatology, Birmingham, Alabama +211 locations
Total Dermatology, Birmingham, Alabama
Chandler Clinical Trials, Chandler, Arizona
Alliance Dermatology, Pheonix, Arizona
Noble Clinical Research, Tucson, Arizona
Northwest AR Clinical Trials Center PLLC, Rogers, Arkansas
Exalt Clinical Research Inc, Chula Vista, California
California Dermatology and Clinical Research Institute, Encinitas, California
Raoof MD, Encino, California
Marvel Clinical Research LLC, Huntington Beach, California
Long Beach Research Institute, Long Beach, California
Olive View UCLA Education and Research Institute, Los Angeles, California
Dermatology Research Associates, Los Angeles, California
Wallace Medical Group Inc, Los Angeles, California
Northridge Clinical Trials, Northridge, California
Empire Clinical Research Pomona, Pomona, California
Integrative Skin Science and Research, Sacramento, California
Therapeutics Clinical Research, San Diego, California
Southern California Clinical Research, Santa Ana, California
Clinical Science Institute Dermatology Institute, Santa Monica, California
Unison Clinical Trials, Sherman Oaks, California
California Dermatology Institute Thousand Oaks, Thousand Oaks, California
Sunwise Clinical Research LLC, Walnut Creek, California
Clearlyderm Dermatology West Boca Raton, Boca Raton, Florida
Driven Clinical Research, Coral Gables, Florida
FXM Clinical Research Ft. Lauderdale LLC, Fort Lauderdale, Florida
Direct Helpers Research Center, Hialeah, Florida
Glick Skin Institute, Margate, Florida
Procare Research Center, Miami Gardens, Florida
San Marcus Research Clinic Inc - Miami, Miami Lakes, Florida
Savin Medical Group LLC, Miami Lakes, Florida
AppleMed Research Group, Miami, Florida
FAX Pharma Clinical Research Inc, Miami, Florida
FXM Clinical Research Miami LLC, Miami, Florida
Las Mercedes Medical Research, Miami, Florida
FXM Clinical Research Miramar LLC, Miramar, Florida
Oceanic Research Group, North Miami Beach, Florida
Renstar Medical Research, Ocala, Florida
Lenus Research and Medical Group LLC, Sweetwater, Florida
Advanced Clinical Research Institute, Tampa, Florida
ForCare Medical Center, Tampa, Florida
Arlington Dermatology, Rolling Meadows, Illinois
NorthShore Medical Group Dermatology Skokie, Skokie, Illinois
Dundee Dermatology, West Dundee, Illinois
DS Research of Southern Indiana, Clarksville, Indiana
Dawes Fretzin Clinical Research Group, Columbus, Indiana
The Indiana Clinical Trials Center, Plainfield, Indiana
The South Bend Clinic, South Bend, Indiana
Equity Medical, Bowling Green, Kentucky
DS Research of Kentucky, Louisville, Kentucky
Velocity Clinical Research, Baton Rouge, Louisiana
MetroBoston Clinical Partners, Brighton, Massachusetts
Michigan Center for Research Company, Clarkston, Michigan
Henry Ford Medical Center Farmington, Detroit, Michigan
Revival Research Institute, Troy, Michigan
Grekin Skin Institute, Warren, Michigan
Associated Skin Care Specialists Minnesota Clinical Study Center, New Brighton, Minnesota
Cleaver Dermatology, Kirksville, Missouri
NYC Health and Hospitals Elmhurst, Elmhurst, New York
Pioneer Clinical Research NY, New York, New York
OptiSkin, New York, New York
DermResearchCenter of New York, Stony Brook, New York
WDC Cosmetic and Research, Wilmington, North Carolina
Optima Research Boardman, Boardman, Ohio
The Ohio State University Wexner Medical Center OSUWMC OSU Dermatology East Columbus, Gahanna, Ohio
Dermatologists of Southwestern Ohio LLC, Mason, Ohio
Unity Clinical Research UCR, Oklahoma City, Oklahoma
Velocity Clinical Research, Medford, Oregon
Oregon Medical Research Center, Portland, Oregon
Paddington Testing Company Inc, Philadelphia, Pennsylvania
Clinical Partners LLC, Johnston, Rhode Island
Studies in Dermatology LLC, Cypress, Texas
Modern Research Associates PLLC, Dallas, Texas
Reveal Research Institute, Frisco, Texas
Center for Clinical Studies Texas Medical Center, Houston, Texas
Austin Institute for Clinical Research, Houston, Texas
SMS Clinical Research, Mesquite, Texas
Progressive Clinical Research San Antonio, San Antonio, Texas
Center for Clinical Studies (CCS) - Webster/Clear Lake Location, Webster, Texas
Jordan Valley Dermatology, South Jordan, Utah
Frontier Dermatology, Mill Creek, Washington
Premier Specialist, Kogarah, New South Wales
North Eastern Health Specialists, Campbelltown, South Australia
Skin Health Institute, Carlton, Victoria
Sinclair Dermatology, East Melbourne, Victoria
Multiprofile Hospital for Active Treatment Dr Tota Venkova, Gabrovo, Not set
DCC Aleksandrovka, Sofia, Not set
Enverus Medical, Surrey, British Columbia
CCA Medical Research Corp, Ajax, Ontario
SimcoDerm Medical and Surgical Dermatology Center, Barrie, Ontario
Guelph Dermatology Research, Guelph, Ontario
Dermatrials Research Inc, Hamilton, Ontario
Centricity Research London, London, Ontario
Derm Effects, London, Ontario
Lynderm Research, Markham, Ontario
DermEdge Research Inc, Mississauga, Ontario
Clear Skin Dermatology, Newmarket, Ontario
North Bay Dermatolgy Centre, North Bay, Ontario
Canadian Dermatology Centre, North York, Ontario
Institute of Cosmetic and Laser Surgery, Oakville, Ontario
The Centre for Dermatology, Richmond Hill, Ontario
North York Research Inc, Toronto, Ontario
Toronto Research Centre, Toronto, Ontario
XLR8 Medical Research, Windsor, Ontario
Innovaderm, Montréal, Quebec
Centre of Research in Dermatology Quebec CRDQ, Québec, Quebec
Dermatologie Sima Inc, Verdun, Quebec
Dermamedica, Náchod, Kralovehradecky kraj
Vesalion s.r.o, Ostrava, Moravian Silesian
Pratia Brno, Brno, Not set
Lékárna Pod Kaňkem, Kutná Hora, Not set
Nemocnice Novy Jicin, Nový Jičín, Not set
Dermskin sro, Olomouc, Not set
CCR Ostrava, Ostrava, Not set
Pratia Pardubice as, Pardubice, Not set
Sanatorium Profesora Arenbergera, Prague, Not set
Fakultni Nemocnice Kralovske Vinohrady FNKV Dermatovenerologicka Klinika, Prague, Not set
Pratia Prague, Prague, Not set
Praglandia, Prague, Not set
Clintrial sro, Praha, Not set
Dermatologicka ambulance Svitavy, Svitavy, Not set
Innomedica, Tallinn, Harjumaa
Center for Clinical and Basic Research AS, Tallinn, Not set
Kliiniliste Uuringute Keskus OU, Tartu, Not set
Centre Azur Nice, Nice, Alpes Maritimes
Hautarztpraxis Mahlow, Mahlow, Brandenburg
Universitatsklinikum Frankfurt, Frankfurt, Hessen
Rosenpark Research, Darmstadt, Hesse
Fachklinik Bad Bentheim, Bad Bentheim, Lower Saxony
Klinikum Bielefeld, Bielefeld, North Rhine-Westphalia
Intramedis CSS, Remscheid, NRW
Dermatologische Praxis Dres Quist, Mainz, Rhinelkand-Palatinate
Klinische Forschung Dresden GmbH, Dresden, Sachsen
Praxis fur Dermatologie und Venerologie, Dresden, Saxony
Universitatsklinikum Schleswig Holstein, Kiel, Schleswig Holstein
Universitatsklinikum Schleswig Holstein, Luebeck, Schleswig Holstein
Hautarztpraxis Dr Mihaescu, Augsburg, Not set
ISA - Interdisciplinary Study Association GmbH, Berlin, Not set
Universitaetsklinikum Muenster, Münster, Not set
KliFOs Klinische Forschung Osnabruck, Osnabrück, Not set
Allergo-Derm Bakos Kft, Szolnok, JN
DermaMed Research Kf, Békés, Oroshaza
UNO Medical Trials Kft., Budapest, Not set
Orvostudomanyi Kutato es Fejleszto Kft, Debrecen, Not set
DERMA B Kft, Debrecen, Not set
Mie University Hospital, Tsu, Mie
Osaka Metropolitan University Hospital, Osaka, Osaka-shi
Nippon Life Hospital, Osaka, Osaka-Shi
Dermatology and Ophthalmology Kume Clinic, Sakai, Osaka
Medical Corporation Jitai kai Tachikawa Dermatology Clinic, Tachikawa, Tokyo
Chosun Universtiy Hospital, Gwangju, Dong-gu
Hallym University Sacred Heart Hospital, Anyang-si, Gyeonggi-do
Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do
Seoul National University Hospital, Seoul, Not set
Konkuk University Medical Center, Seoul, Not set
Semigallia Ltd, Kuldīga, Kuldigas
Riga 1st Hospital, Riga, Not set
Med Art clinic, Riga, Not set
Veselibas Centrs 4, Riga, Not set
SIA Veseliba un estetika, Riga, Not set
Veselibas Centrs 4 Filiale Dermatologijas Klinika, Riga, Not set
Smite Aija medical practice in dermatology venereology, Talsi, Not set
Specderm, Podlaski, Bialystok
Synexus Centrum Medyczne Osteomed Wroclaw, Wrocław, Dolnoslaskie
Centrum Medyczne Pratia Bydgoszcz, Bydgoszcz, Kujawsko pomorskie
Dermoklinika, Łódź, Lodzkie
FutureMeds Lodz, Łódź, Lodzkie
Velocity Clinical Research Skierniewice, Skierniewice, Lodz
WroMedica, Wrocław, Lower Silesia
Centrum Medyczne dr Rajzer spolka zoo, Kraków, Malopolska
Diamond Clinic, Kraków, Malopolska
Clinical Best Solutions, Warsaw, Masovian
Centrum Medyczne Evimed, Warsaw, Masovian
FutureMeds Warszawa Centrum, Warsaw, Mazovia
MICS Medical Center Warsaw, Warsaw, Mazovia
High Med Przychodnia Specjalistyczna, Warsaw, Mazovia
Centrum Medyczne Reuma Park, Warsaw, Mazovia
RoyalDerm, Warszawa, Mazowiecke
RCMed Oddział Sochaczew, Sochaczew, Mazowieckie
ClinicMed Daniluk Nowak SpK, Białystok, Podlaskie
AES Gdansk, Gdańsk, Pomorskie
Pratia Gdynia, Gdynia, Pomorskie
Derm Art Institute, Gdynia, Pomorskie
Synexus Sp zo o Oddzial w Gdyni, Gdynia, Pomorskie
Centrum Badan Klinicznych PI House, Gdańsk, Poneranian
Pratia Katowice, Katowice, Silesia
Centrum Medyczne Angelius Provita, Katowice, Silesia
Research Solutions, Katowice, Slaskie
Laser Clinic, Szczecin, Zachodniopomorskie
Care Clinic Katowice, Katowice, Not set
Centrum Medyczne All Med Badania Kliniczne, Kraków, Not set
Pratia MCM Krakow, Kraków, Not set
Krakowskie Centrum Medyczne, Kraków, Not set
Klinika Dermatologii Uniwersytecki Szpital Kliniczny im F Chopina, Rzeszów, Not set
Rheuma Medicus, Warsaw, Not set
MTZ Clinical Research Sp z o o, Warsaw, Not set
Centrum Medyczne Synexus Warszawa, Warsaw, Not set
Klinika Ambroziak Dermatologia Kliniczna, Warszawa, Not set
dermMedica, Wrocław, Not set
Hospital da Senhora da Oliveira, Guimaraes, Braga
Hospital CUF Descobertas, Lisbon, Not set
Unidade Local de Saude Santo Antonio Hospital de Santo Antonio, Porto, Not set
Centro Reumatologico de Cagus, Caguas, Not set
Ponce Medical School Foundation Inc, Ponce, Not set
Clinical Research Puerto Rico, San Juan, Not set
GCM Medical Group PSC Hato Rey Site, San Juan, Not set
Hospital Clínico Universitario de Santiago de Compostela, A Coruña, Santiago de Compostela
University General Hospital Dr Balmis, Alicante, Not set
Hospital del Mar, Barcelona, Not set
Hospital de la Santa Creu i Sant Pau, Barcelona, Not set
Hospital Germans Trias i Pujol, Barcelona, Not set
Hospital Universitario La Paz, Madrid, Not set
Hospital de Manises, Manises, Not set
Microvascular Monitoring in Circulatory Shock and Sepsis (MiMICSS)
Recruiting
Investigation of the feasibility of using near-infrared spectroscopy (NIRS) to monitor microvascular function in critically ill patients.
Investigation of the feasibility of using near-infrared spectroscopy (NIRS) to monitor microvascular function in critically ill patients. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/19/2025
Locations: Health Sciences Centre Winnipeg, Winnipeg, Manitoba
Health Sciences Centre Winnipeg, Winnipeg, Manitoba
Conditions: Sepsis, Shock, Critical Illness
A Study of Zanubrutinib Plus Anti-CD20 Versus Lenalidomide Plus Rituximab in Participants With Relapsed/Refractory Follicular or Marginal Zone Lymphoma
Recruiting
The purpose of the study is to compare the efficacy of zanubrutinib plus obinutuzumab versus lenalidomide plus rituximab (R\^2) in participants with relapsed/refractory (R/R) follicular lymphoma (FL), as measured by progression-free survival as determined by an independent review committee in accordance with the 2014 modification of the International Working Group on non-Hodgkin lymphoma (NHL) Criteria based on n positron emission tomography and computed tomography (PET/CT), and to compare the e... Read More
The purpose of the study is to compare the efficacy of zanubrutinib plus obinutuzumab versus lenalidomide plus rituximab (R\^2) in participants with relapsed/refractory (R/R) follicular lymphoma (FL), as measured by progression-free survival as determined by an independent review committee in accordance with the 2014 modification of the International Working Group on non-Hodgkin lymphoma (NHL) Criteria based on n positron emission tomography and computed tomography (PET/CT), and to compare the efficacy of zanubrutinib plus rituximab versus R\^2 in participants with R/R marginal zone lymphoma (MZL), as measured by progression free survival (PFS) assessed by IRC in accordance with CT-based Lugano 2014 Criteria. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/19/2025
Locations: Ucsf Fresno University of California San Francisco Fresno, Fresno, California +264 locations
Ucsf Fresno University of California San Francisco Fresno, Fresno, California
Cancer and Blood Specialty Clinic, Los Alamitos, California
Los Angeles Cancer Network, Los Angeles, California
Valkyrie Clinical Trials, Los Angeles, California
Sharp Healthcare Sharp Memorial Hospital, San Diego, California
Baptist Md Anderson Cancer Center, Jacksonville, Florida
Northwest Georgia Oncology Centers Marietta, Marietta, Georgia
Fort Wayne Medical Oncology and Hematology, Fort Wayne, Indiana
Mission Cancer and Blood, Waukee, Iowa
Cancer Center of Kansas, Wichita, Kansas
Baptist Health Lexington, Lexington, Kentucky
Christus Highland Cancer Treatment Center, Shreveport, Louisiana
University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, Maryland
American Oncology Partners of Maryland Pa, Bethesda, Maryland
Henry Ford Hospital, Detroit, Michigan
Corewell Health the Michigan Cancer Consortium, Grand Rapids, Michigan
Hattiesburg Hematology and Oncology Clinic, Hattiesburg, Mississippi
University of Missouri Hospital, Ellis Fischel Cancer Center, Columbia, Missouri
Oncology Hematology Associates, Springfield, Missouri
Nebraska Cancer Specialists, Omaha, Nebraska
Iyengar Hematology Oncology Medical Center Pa, Bayonne, New Jersey
New York Cancer and Blood Specialists, East Setauket, New York
Clinical Research Alliance, Inc, Westbury, New York
Levine Cancer Institute Wake Forest, Charlotte, North Carolina
Cancer Care Associates of York, York, Pennsylvania
Prairie Lakes Healthcare System, Watertown, South Dakota
Texas Oncology Baylorcharles A Sammons Cancer Center, Dallas, Texas
Md Anderson Cancer Center, Houston, Texas
Northeast Texas Cancer and Research Institute, Tyler, Texas
University of Washington, Seattle, Washington
Northwest Medical Specialties, Tacoma, Washington
Hospital Aleman, Caba, Not set
Hospital Italiano de Buenos Aires, Ciudad Autonoma Buenos Aires, Not set
Concord Repatriation General Hospital, Concord, New South Wales
Gosford Hospital, Gosford, New South Wales
St George Hospital, Kogarah, New South Wales
Orange Health Hospital, Orange, New South Wales
Port Macquarie Base Hospital, Port Macquarie, New South Wales
Westmead Hospital, Westmead, New South Wales
Sunshine Coast Hospital and Health Service, Birtinya, Queensland
Townsville University Hospital, Douglas, Queensland
Genesiscare North Adelaide, North Adelaide, South Australia
Monash Health, Clayton, Victoria
Epworth Freemasons, East Melbourne, Victoria
St Vincents Hospital Melbourne, Fitzroy, Victoria
Austin Health, Heidelberg, Victoria
Cabrini Hospital Malvern, Malvern East, Victoria
The Alfred Hospital, Melbourne, Victoria
La Trobe Regional Hospital, Melbourne, Victoria
Royal Perth Hospital, Perth, Western Australia
Perth Blood Institute, West Perth, Western Australia
Medizinische Universitatsklinik Innsbruck, Innsbruck, Not set
Uk St Poelten, St Polten, Not set
Medical Univeristy Vienna, Wien, Not set
Hanusch Krankenhaus, Wien, Not set
Wiener Gesundheitsverbund Klinik Ottakring, Wien, Not set
Institut Jules Bordet, Anderlecht, Not set
Az Sint Jan Brugge, Brugge, Not set
Universitair Ziekenhuis Gent, Gand, Not set
University Hospitals Leuven, Leuven, Not set
Hospital de Amor Barretos, Barretos, Not set
Clinica de Oncologia Reichow, Blumenau, Not set
Unesp Faculdade de Medicina Da Universidade Estadual Paulista Campus Botucatu, Botucatu, Not set
Instituto Dor de Pesquisa E Ensino Distrito Federal, Brasilia, Not set
Universidade de Campinas Centro de Hematologia E Hemoterapia, Campinas, Not set
Fundacao Universidade de Caxias Do Sul, Caxias do Sul, Not set
Centro Integrado de Oncologia de Curitiba Ss Cionc, Curitiba, Not set
Hospital Erasto Gaertner, Curitiba, Not set
Centro de Ensino E Pesquisa Em Oncologia de Santa Catarina (Cepen), Florianopolis, Not set
Complexo Hospitalar de Niteroi, Niteroi, Not set
Centro Gaucho Integrado de Oncologia Hospital Mae de Deus, Porto Alegre, Not set
Instituto Dor de Pesquisa E Ensino Pernambuco, Recife, Not set
Instituto Dor de Pesquisa E Ensino, Recife, Not set
Hospital Das Clinicas Da Faculdade de Medicina de Ribeirao Preto Usp, Ribeirao Preto, Not set
Instituto Americas Ensino, Pesquisa E Inovacao, Rio de Janeiro, Not set
Hospital Sao Rafaelinstituto Dor de Pesquisa E Ensino, Salvador, Not set
Ensino E Terapia de Inovacao Clinica Amo Etica, Salvador, Not set
Hospital Nove de Julho Dasa, Sao Paulo, Not set
Instituto Dor de Pesquisa E Ensino Sao Paulo, Sao Paulo, Not set
Hcfmusp Servico de Hematologia, Hemoterapia E Terapia Celular, Sao Paulo, Not set
Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein, Sao Paulo, Not set
Hospital Santa Rita de Cassia Afecc, Vitoria, Not set
Umhat Svgeorgi Ead, Plovdiv, Not set
Acibadem City Clinic Tokuda Umhat Ead, Department of Medical Oncology, Sofia, Not set
University Multiprofile Hospital For Active Treatment Saint Ivan Rilski, Sofia, Not set
NHATHD, Sofia, Not set
British Columbia Cancer Agency the Vancouver Centre, Vancouver, British Columbia
Newfoundland and Labrador Health Services, St Johns, Newfoundland and Labrador
Queen Elizabeth Ii Health Sciences Centre, Halifax, Nova Scotia
Juravinski Cancer Centre, Hamilton, Ontario
London Health Sciences Centre, London, Ontario
Ciusss Du Saguenay Lac St Jean, Chicoutimi, Quebec
Centre Integre de Sante Et de Services Sociaux de Chaudiere Appalaches, Levis, Quebec
Ciusss de Lest de Lile de Montreal Hopital Maisonneuve Rosemont, Montreal, Quebec
Unite de Recherche Clinique Du Cisss Des Laurentides, SaintJerome, Quebec
Ciusss de Lestrie Chus, Sherbrooke, Quebec
Chu de Quebec Universite Laval, Hopital de Lenfant Jesus, Centre Integre de Cancerologie (Cic), Quebec, Not set
The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui
Beijing Friendship Hospital, Capital Medical University, Beijing, Beijing
Beijing Cancer Hospital, Beijing, Beijing
Beijing Friendship Hospital, Capital Medical University(Tongzhou), Beijing, Beijing
Chongqing Cancer Hospital, Chongqing, Chongqing
Fujian Medical University Union Hospital, Fuzhou, Fujian
The First Affiliated Hospital of Xiamen University, Xiamen, Fujian
The First Peoples Hospital of Foshan, Foshan, Guangdong
Sun Yat Sen University Cancer Center, Guangzhou, Guangdong
Huizhou Central Peoples Hospital, Huizhou, Guangdong
Meizhou People Hospital, Meizhou, Guangdong
Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong
Harbin Medical University Cancer Hospital, Harbin, Heilongjiang
Anyang Tumor Hospital, Anyang, Henan
Henan Cancer Hospital, Zhengzhou, Henan
Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei
Tongji Hospital of Tongji Medical College Huazhong University of Science and Technology, Wuhan, Hubei
The First Peoples Hospital of Changde City, Changde, Hunan
Jiangsu Province Hospital, Nanjing, Jiangsu
Affiliated Hospital of Nantong University, Nantong, Jiangsu
The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu
Wuxi Peoples Hospital, Wuxi, Jiangsu
The First Affiliated Hospital of Nanchang University Branch Donghu, Nanchang, Jiangxi
Jiangxi Province Cancer Hospital, Nanchang, Jiangxi
The First Affiliated Hospital of Nanchang University Branch Xianghu, Nanchang, Jiangxi
The First Hospital of Jilin University, Changchun, Jilin
Shengjing Hospital of China Medical University, Shenyang, Liaoning
Liaoning Cancer Hospital and Institute, Shenyang, Liaoning
Peoples Hospital of Rizhao, Rizhao, Shandong
The Second Affiliated Hospital of Shandong First Medical University, Taian, Shandong
Fudan University Shanghai Cancer Center, Shanghai, Shanghai
Shanxi Provincial Cancer Hospital, Taiyuan, Shanxi
West China Hospital, Sichuan University, Chengdu, Sichuan
Dongyang Peoples Hospital, Dongyang, Zhejiang
Zhejiang Cancer Hospital, Hangzhou, Zhejiang
The First Hospital of Jiaxing, Jiaxing, Zhejiang
Jinhua Municipal Central Hospital, Jinhua, Zhejiang
The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang
Fakultni Nemocnice Hradec Kralove, Hradec Kralove, Not set
Fakultni Nemocnice Olomouc, Olomouc, Not set
Hopital Prive Dantony, Departement Dhemathologie, Antony, Not set
Centre Hospitalier Le Mans, Le Mans, Not set
Chu Montpellier Hopital Saint Eloi, Montpellier, Not set
Hopital Larchet Chu Nice, Nice, Not set
Institut Curie, Paris, Not set
Necker University Hospital, Paris, Not set
Icans Institut de Cancerologie Strasbourg Europe, Strasbourg, Not set
Chu Nancy Hopital Brabois, VandoeuvrelesNancy, Not set
High Technology Hospital Medcenter Ltd, Batumi, Not set
JSC VIAN, Kutaisi, Not set
K Eristavi National Center of Experimental and Clinical Surgery Jsc, Tbilisi, Not set
Oncology Research Center Ltd, Tbilisi, Not set
Universitaetsklinikum Essen, Essen, Not set
Universitaetsklinikum Ulm, Ulm, Not set
University Hospital of Alexandroupolis, Alexandroupolis, Not set
Evaggelismos, Athens, Not set
General Hospital of Athens Alexandra, Athens, Not set
University Hospital of Patra, Patras, Not set
St Jamess Hospital, Dublin, Not set
University Hospital Waterford, Waterford, Not set
Haemek Medical Center, Afula, Not set
Assuta Ashdod Medical Center, Ashdod, Not set
Shaare Zedek Medical Center, Jerusalem, Not set
Hadassah En Karem Medical Center, Jerusalem, Not set
Rabin Medical Center, Petach Tikva, Not set
Chaim Sheba Medical Center, Ramat gan, Not set
Assuta Medical Center, Tel Aviv Jaffa, Not set
Sourasky Tel Aviv Medical Center, Tel Aviv Jaffa, Not set
Cro Irccs Aviano, Aviano, Not set
Irccs Azienda Ospedaliero Universitaria Bologna, Bologna, Not set
Aou Careggi, Servizio Sanitario Toscana, Firenze, Not set
Istituto Europeo Di Oncologia, Milano, Not set
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda, Milano, Not set
Aou Maggiore Della Carita, Novara, Not set
Azienda Ospedaliera Di Padova, Padova, Not set
Irccs Policlinico San Matteo, Universita Degli Studi Di Pavi, Pavia, Not set
Arcispedale S Maria Nuova Ausl Reggio Emilia Hematology Unit, Reggio Emilia, Not set
Aou Santa Maria Della Misericordia Di Udine, Udine, Not set
Ospedale Di Circolo E Fondazione Macchi, Varese, Not set
Aichi Cancer Center Hospital Clinical Oncology, Nagoya, Aichi
Chiba Cancer Center, Chibashi, Chiba
Matsuyama Red Cross Hospital, Matsuyamashi, Ehime
Hiroshima Red Cross Hospital and Atomic Bomb Survivors Hospital, Hiroshimashi, Hiroshima
National Hospital Organization Hokkaido Cancer Center, SapporoShi, Hokkaido
Aiiku Hospital, SapporoShi, Hokkaido
Kagoshima University Hospital, Kagoshimashi, Kagoshima
Kanagawa Cancer Center, Yokohamashi, Kanagawa
University Hospital, Kyoto Prefectural Univ of Medicine, KyotoShi, Kyoto
Tohoku University Hospital, Sendaishi, Miyagi
Kurashiki Central Hospital, Kurashikishi, Okayama
Kansai Medical University Hospital, Hirakata, Osaka
Kindai University Hospital, Osakasayama, Osaka
Tokyo Metropolitan Komagome Hospital, Bunkyoku, Tokyo
National Cancer Center Hospital, ChuoKu, Tokyo
Cancer Institute Hospital of Jfcr, Kotoku, Tokyo
Yamagata University Hospital, Yamagatashi, Yamagata
Kumamoto University Hospital, Kumamoto, Not set
National Hospital Organization Okayama Medical Center, Okayama, Not set
Yokohama Municipal Citizens Hospital, YokohamaShi, Not set
Inje University Busan Paik Hospital, BusanjinGu, Busan Gwang'yeogsi
Dong A University Hospital, SeoGu, Busan Gwang'yeogsi
Pusan National University Hospital, SeoGu, Busan Gwang'yeogsi
Seoul National University Bundang Hospital, BundangGu SeongnamSi, Gyeonggi-do
Kyungpook National University Chilgok Hospital, BukGu, Gyeongsangbukdo
Gyeongsang National University Hospital, JinjuSi, Gyeongsangnamdo
Chonnam National University Hwasun Hospital, HwasunGun, Jeollanam-do
Samsung Medical Center, GangnamGu, Seoul Teugbyeolsi
The Catholic University of Korea, Seoul St Marys Hospital, SeochoGu, Seoul Teugbyeolsi
Severance Hospital Yonsei University Health System, SeodaemunGu, Seoul Teugbyeolsi
Seoul National University Hospital, Seoul, Seoul Teugbyeolsi
Asan Medical Center, SongpaGu, Seoul Teugbyeolsi
Soon Chun Hyang University Hospital Seoul, YongsanGu, Seoul Teugbyeolsi
Szpital Uniwersytecki Nr Im Dr Jana Biziela, Bydgoszcz, Not set
Uniwersyteckie Centrum Kliniczne Klinika Hematologii I Transplantologii, Gdansk, Not set
Pratia Onkologia Katowice, Katowice, Not set
Pratia McM Krakow, Krakow, Not set
Uniwersytecki Szpital Kliniczny W Poznaniu, Oddzial Hematologii I Transplantacji Szpiku, Poznan, Not set
Wojewodzki Szpital Zespolony Im L Rydygiera W Toruniu, Torun, Not set
Centralny Szpital Kliniczny Uck Wum, Warszawa, Not set
Instytut Hematologii I Transfuzjologii, Warszawa, Not set
Narodowy Instytut Onkologii Im Marii Skodowskiej Curie Hematology Unit, Warszawa, Not set
Hospital de Braga, Braga, Not set
Instituto Portugues de Oncologia Do Porto Francisco Gentil, Epe, Porto, Not set
Unidade Local de Saude Gaia E Espinho, VILA NOVA DE GAIA Porto, Not set
Auxilio Mutuo Cancer Center, San Juan, Not set
Coltea Clinical Hospital, Bucharest, Not set
Institutul Oncologic Prof Dr Ion Chiricuta Cluj Napoca, ClujNapoca, Not set
Institutul Regional de Oncologie Iasi, Iasi, Not set
Spitalul Clinic Judetean de Urgenta Bihor, Oradea, Not set
Haemalife, Kuils River, Not set
Alberts Cellular Therapy, Pretoria, Not set
Ico Badalona, Badalona, Not set
Hospital Universitario de Burgos, Burgos, Not set
Hospital Universitario Puerta Del Mar, Cadiz, Not set
Hospital Universitario Virgen de Las Nieves, Granada, Not set
Institut Catala Doncologia Hospital Duran I Reynals, Hospitalet de LLobregat, Not set
Complejo Asistencial Universitario de Leon, Leon, Not set
Hospital de La Princesa, Madrid, Not set
Clinica Universidad de Navarra, Madrid, Not set
Hospital Universitario Infanta Leonor, Madrid, Not set
Hospital Universitario Ramon Y Cajal, Madrid, Not set
H Puerta de Hierro Majadahonda, Majadahonda, Not set
Hospital Clinico Universitario Virgen de La Arrixaca, Murcia, Not set
Clinica Universidad de Navarra Pamplona, Pamplona, Not set
Hospital Universitario Quironsalud Madrid, Pozuelo de Alarcon, Not set
Hospital Universitario de Salamanca, Salamanca, Not set
Hospital Universitario Virgen Del Rocio, Sevilla, Not set
Hospital Universitari Mutua Terrassa, Terrassa, Not set
St Claraspital, Basel, Not set
Hfr Fribourg, Fribourg, Not set
Reseau Hospitalier Neuchatelois, La ChauxdeFonds, Not set
Universitatsspital Zurich, Zurich, Not set
Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Not set
Ankara University Medical Faculty, Ankara, Not set
Gazi University Medical School, AOCiftlii, Not set
Ondokuz Mayis University Medicine Faculty Hospital, Atakum Samsun, Not set
Bagcilar Medipol Mega Hospital, Istanbul, Not set
Kocaeli Universitesi Tip Fakultesi, Kocaeli, Not set
Vkv American Hospital, Tevikiye, Not set
Beatson West of Scotland Cancer Centre, Glasgow, Not set
The Christie Hospital, Greater Manchester, Not set
Huddersfield Royal Infirmary, Huddersfield, Not set
Nhs Highland, Inverness, Not set
The Leeds Teaching Hospitals Nhs Trust, Leeds, Not set
Barts Health Nhs Trust, London, Not set
University College Hospital, London, Not set
Derriford Hospital, Plymouth, Not set
Southampton General Hospital, Southampton, Not set
Conditions: Relapsed/Refractory Follicular Lymphoma, Marginal Zone Lymphoma
A 2-stage, Phase III Study to Investigate the Efficacy and Safety of Anifrolumab in Adults With Chronic and/or Subacute Cutaneous Lupus Erythematosus
Recruiting
This study aims to evaluate the efficacy and safety of subcutaneous (SC) anifrolumab versus placebo in adult participants with cutaneous lupus erythematosus (CLE).
This study aims to evaluate the efficacy and safety of subcutaneous (SC) anifrolumab versus placebo in adult participants with cutaneous lupus erythematosus (CLE). Read Less
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
08/19/2025
Locations: Research Site, Glendale, Arizona +271 locations
Research Site, Glendale, Arizona
Research Site, Phoenix, Arizona
Research Site, Covina, California
Research Site, Fountain Valley, California
Research Site, La Jolla, California
Research Site, Los Angeles, California
Research Site, Los Angeles, California
Research Site, Orange, California
Research Site, San Francisco, California
Research Site, Aurora, Colorado
Research Site, Denver, Colorado
Research Site, New Haven, Connecticut
Research Site, Washington, District of Columbia
Research Site, Fort Lauderdale, Florida
Research Site, Miami, Florida
Research Site, Miami, Florida
Research Site, Plantation, Florida
Research Site, Chicago, Illinois
Research Site, Chicago, Illinois
Research Site, Indianapolis, Indiana
Research Site, Murray, Kentucky
Research Site, Baltimore, Maryland
Research Site, Boston, Massachusetts
Research Site, Boston, Massachusetts
Research Site, Ann Arbor, Michigan
Research Site, Ann Arbor, Michigan
Research Site, Bloomfield Hills, Michigan
Research Site, Rochester, Minnesota
Research Site, Omaha, Nebraska
Research Site, Midland Park, New Jersey
Research Site, Brooklyn, New York
Research Site, New York, New York
Research Site, New York, New York
Research Site, Rochester, New York
Research Site, Chapel Hill, North Carolina
Research Site, Charlotte, North Carolina
Research Site, Statesville, North Carolina
Research Site, Cleveland, Ohio
Research Site, Cleveland, Ohio
Research Site, Portland, Oregon
Research Site, Philadelphia, Pennsylvania
Research Site, Providence, Rhode Island
Research Site, Charleston, South Carolina
Research Site, Summerville, South Carolina
Research Site, Dallas, Texas
Research Site, Galveston, Texas
Research Site, Mesquite, Texas
Research Site, Charlottesville, Virginia
Research Site, Roanoke, Virginia
Research Site, Seattle, Washington
Research Site, Ciudad de Buenos Aires, Not set
Research Site, Córdoba, Not set
Research Site, Córdoba, Not set
Research Site, Quilmes, Not set
Research Site, Rosario, Not set
Research Site, San Miguel, Not set
Research Site, Box Hill, Not set
Research Site, Clayton, Not set
Research Site, Kogarah, Not set
Research Site, Malvern, Not set
Research Site, Melbourne, Not set
Research Site, Westmead, Not set
Research Site, Woolloongabba, Not set
Research Site, Graz, Not set
Research Site, Innsbruck, Not set
Research Site, Linz, Not set
Research Site, St. Pölten, Not set
Research Site, Wien, Not set
Research Site, Brussel, Not set
Research Site, Leuven, Not set
Research Site, Liège, Not set
Research Site, Belo Horizonte, Not set
Research Site, Belo Horizonte, Not set
Research Site, Porto Alegre, Not set
Research Site, Rio de Janeiro, Not set
Research Site, Salvador, Not set
Research Site, São Paulo, Not set
Research Site, Sofia, Not set
Research Site, Sofia, Not set
Research Site, Sofia, Not set
Research Site, Sofia, Not set
Research Site, Sofia, Not set
Research Site, Edmonton, Alberta
Research Site, Vancouver, British Columbia
Research Site, Hamilton, Ontario
Research Site, Newmarket, Ontario
Research Site, Toronto, Ontario
Research Site, Osorno, Not set
Research Site, Santiago, Not set
Research Site, Santiago, Not set
Research Site, Santiago, Not set
Research Site, Baotou, Not set
Research Site, Beijing, Not set
Research Site, Beijing, Not set
Research Site, Beijing, Not set
Research Site, Changchun, Not set
Research Site, Changsha, Not set
Research Site, Chengdu, Not set
Research Site, Chongqing, Not set
Research Site, Guangzhou, Not set
Research Site, Hangzhou, Not set
Research Site, Heilongjiang, Not set
Research Site, Jinan, Not set
Research Site, Kunming, Not set
Research Site, Nanchang, Not set
Research Site, Nanjing, Not set
Research Site, Shanghai, Not set
Research Site, Shanghai, Not set
Research Site, Shenzhen, Not set
Research Site, Shenzhen, Not set
Research Site, Shenzhen, Not set
Research Site, Shijiazhuang, Not set
Research Site, Urumqi, Not set
Research Site, Wuhan, Not set
Research Site, Zhuzhou, Not set
Research Site, Barranquilla, Not set
Research Site, Barranquilla, Not set
Research Site, Bogota, Not set
Research Site, Chia, Not set
Research Site, Aarhus, Not set
Research Site, København, Not set
Research Site, Bois Guillaume, Not set
Research Site, Bordeaux, Not set
Research Site, Chambray Les Tours, Not set
Research Site, Dijon, Not set
Research Site, Lille Cedex, Not set
Research Site, Lyon, Not set
Research Site, Montivilliers, Not set
Research Site, Nantes, Not set
Research Site, Nice, Not set
Research Site, Paris, Not set
Research Site, Paris, Not set
Research Site, Paris, Not set
Research Site, Paris, Not set
Research Site, Poitiers, Not set
Research Site, Toulouse Cedex 9, Not set
Research Site, Berlin, Not set
Research Site, Bochum, Not set
Research Site, Dresden, Not set
Research Site, Erlangen, Not set
Research Site, Essen, Not set
Research Site, Freiburg, Not set
Research Site, Hamburg, Not set
Research Site, Hannover, Not set
Research Site, Kiel, Not set
Research Site, Leipzig, Not set
Research Site, Mainz, Not set
Research Site, Marburg, Not set
Research Site, Regensburg, Not set
Research Site, Wuppertal, Not set
Research Site, Athens, Not set
Research Site, Athens, Not set
Research Site, Athens, Not set
Research Site, Athens, Not set
Research Site, Athens, Not set
Research Site, Brescia, Not set
Research Site, Cona, Not set
Research Site, Florence, Not set
Research Site, Marche, Not set
Research Site, Milano, Not set
Research Site, Napoli, Not set
Research Site, Reggio Emilia, Not set
Research Site, Roma, Not set
Research Site, Rome, Not set
Research Site, Bunkyo-ku, Not set
Research Site, Chuo-ku, Not set
Research Site, Fukuoka-Shi, Not set
Research Site, Itabashi, Not set
Research Site, Kanazawa-shi, Not set
Research Site, Kita-gun, Not set
Research Site, Nagasaki-shi, Not set
Research Site, Nagoya-shi, Not set
Research Site, Nagoya, Not set
Research Site, Okayama-shi, Not set
Research Site, Omura-shi, Not set
Research Site, Ono, Not set
Research Site, Osaka-shi, Not set
Research Site, Sapporo, Not set
Research Site, Suita, Not set
Research Site, Wakayama, Not set
Research Site, Yokohama-shi, Not set
Research Site, Yokohama, Not set
Research Site, Yotsukaido-shi, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Seoul, Not set
Research Site, Ciudad de Mexico, Not set
Research Site, Cuernavaca, Not set
Research Site, Guadalajara, Not set
Research Site, Guadalajara, Not set
Research Site, Guadalajara, Not set
Research Site, Guadalajara, Not set
Research Site, San Luis Potosi, Not set
Research Site, Veracruz, Not set
Research Site, Zapopan, Not set
Research Site, Amsterdam, Not set
Research Site, Breda, Not set
Research Site, Nijmegen, Not set
Research Site, Rotterdam, Not set
Research Site, Hamilton, Not set
Research Site, Papatoetoe, Not set
Research Site, Iloilo City, Not set
Research Site, Lipa, Not set
Research Site, Manila, Not set
Research Site, Gdynia, Not set
Research Site, Katowice, Not set
Research Site, Kielce, Not set
Research Site, Olsztyn, Not set
Research Site, Ossy, Not set
Research Site, Poznan, Not set
Research Site, Rzeszów, Not set
Research Site, Warszawa, Not set
Research Site, Warszawa, Not set
Research Site, Warszawa, Not set
Research Site, Braga, Not set
Research Site, Coimbra, Not set
Research Site, Lisboa, Not set
Research Site, Porto, Not set
Research Site, Bucharest, Not set
Research Site, Bucuresti, Not set
Research Site, Craiova, Not set
Research Site, Iasi, Not set
Research Site, Targu Mures, Not set
Research Site, Belgrade, Not set
Research Site, Belgrade, Not set
Research Site, Belgrade, Not set
Research Site, Kragujevac, Not set
Research Site, Košice, Not set
Research Site, Piestany, Not set
Research Site, Piestany, Not set
Research Site, Svidnik, Not set
Research Site, Cape Town, Not set
Research Site, Johannesburg, Not set
Research Site, Stellenbosch, Not set
Research Site, A Coruña, Not set
Research Site, Barcelona, Not set
Research Site, Barcelona, Not set
Research Site, Castellon de la Plana, Not set
Research Site, Granada, Not set
Research Site, L' Hospitalet De Llobregat, Not set
Research Site, Las Palmas de Gran Canaria, Not set
Research Site, Madrid, Not set
Research Site, Madrid, Not set
Research Site, Madrid, Not set
Research Site, Madrid, Not set
Research Site, Majadahonda, Not set
Research Site, Salamanca, Not set
Research Site, Sevilla, Not set
Research Site, Valencia, Not set
Research Site, València, Not set
Research Site, Vigo, Not set
Research Site, Kaohsiung, Not set
Research Site, Taichung, Not set
Research Site, Taipei, Not set
Research Site, Taipei, Not set
Research Site, Bangkok, Not set
Research Site, Bangkok, Not set
Research Site, Hat Yai, Not set
Research Site, Khlong Luang, Not set
Research Site, Khon-Kaen, Not set
Research Site, İstanbul, Not set
Research Site, Istanbul, Not set
Research Site, Karsiyaka, Not set
Research Site, Kayseri, Not set
Research Site, Samsun, Not set
Research Site, Cambridge, Not set
Research Site, Leeds, Not set
Research Site, London, Not set
Research Site, London, Not set
Research Site, London, Not set
Research Site, London, Not set
Research Site, Newcastle upon Tyne, Not set
Conditions: Cutaneous Lupus Erythematosus
Efficacy and Safety of Subcutaneous Dupilumab for the Treatment of Adult Participants With Chronic Pruritus of Unknown Origin (CPUO) (LIBERTY-CPUO-CHIC)
Recruiting
The main objective of the study is to assess efficacy and safety of dupilumab given up to 24 weeks in adults with CPUO.
This is a master protocol which includes 2 parallel-treatment, double-blind, 2- arm Phase 3 staggered studies of similar design (Study A and Study B) in male and female participants aged 18 to 90 years with CPUO. Study B design was to be adapted based on the results of Study A.
For both Study A and B, after an up-to-4-week screening period, participants with severe pruritus (... Read More
The main objective of the study is to assess efficacy and safety of dupilumab given up to 24 weeks in adults with CPUO.
This is a master protocol which includes 2 parallel-treatment, double-blind, 2- arm Phase 3 staggered studies of similar design (Study A and Study B) in male and female participants aged 18 to 90 years with CPUO. Study B design was to be adapted based on the results of Study A.
For both Study A and B, after an up-to-4-week screening period, participants with severe pruritus (worst-itch numerical rating scale \[WI-NRS ≥7) will enter a 4-week run-in period and will be treated with a non-sedative antihistamine and an emollient (moisturizer). Participants with severe pruritus (WI-NRS ≥7) at baseline will be randomized (1:1) to be treated for 24 weeks with either dupilumab or matching placebo in addition to their non-sedative antihistamine and emollient regimen. The treatment period for both study A and B will be followed by a 12-week follow-up period. Read Less
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
08/19/2025
Locations: Kern Allergy and Medical Research- Site Number : 8400016, Bakersfield, California +79 locations
Kern Allergy and Medical Research- Site Number : 8400016, Bakersfield, California
Allergy & Rheumatology- Site Number : 8400038, La Jolla, California
FoxHall Dermatology- Site Number : 8400042, Washington, District of Columbia
Palm Harbor Dermatology- Site Number : 8400024, Belleair, Florida
University of Miami Hospital- Site Number : 8400011, Miami, Florida
Skin Care Physicians of Georgia - Macon- Site Number : 8400030, Macon, Georgia
Aeroallergy Research Laboratory- Site Number : 8400036, Savannah, Georgia
Investigational Site Number : 3920001, Elk Grove Village, Illinois
Dawes Fretzin Clinical Research- Site Number : 8400007, Indianapolis, Indiana
Dermatology Specialists Research (DS Research) - Kentucky- Site Number : 8400031, Louisville, Kentucky
Johns Hopkins Hospital- Site Number : 8400020, Baltimore, Maryland
The Asthma and Allergy Center- Site Number : 8400014, Bellevue, Nebraska
Icahn School of Medicine at Mount Sinai- Site Number : 8400034, New York, New York
National Allergy and Asthma - North Charleston - Northside Drive- Site Number : 8400032, North Charleston, South Carolina
Complete Dermatology - Sugar Land- Site Number : 8400046, Sugar Land, Texas
Investigational Site Number : 0320005, Buenos Aires, Not set
Investigational Site Number : 0320001, Buenos Aires, Not set
Investigational Site Number : 0320006, Buenos Aires, Not set
Investigational Site Number : 0320003, Birtinya, Queensland
Investigational Site Number : 0320007, Maroochydore, Queensland
Investigational Site Number : 1240001, Calgary, Alberta
Investigational Site Number : 1240008, Edmonton, Alberta
Investigational Site Number : 1240002, London, Ontario
Investigational Site Number : 1240003, Markham, Ontario
Investigational Site Number : 1240006, Toronto, Ontario
Investigational Site Number : 1240005, Montreal, Quebec
Investigational Site Number : 1240004, Verdun, Quebec
Investigational Site Number : 1560003, Beijing, Not set
Investigational Site Number : 1560004, Chengdu, Not set
Investigational Site Number : 1560009, Chongqing, Not set
Investigational Site Number : 1560006, Guangzhou, Not set
Investigational Site Number : 1560005, Guangzhou, Not set
Investigational Site Number : 1560002, Hangzhou, Not set
Investigational Site Number : 1560001, Shanghai, Not set
Investigational Site Number : 1560011, Suzhou, Not set
Investigational Site Number : 1560008, Wuhan, Not set
Investigational Site Number : 3800007, Varazdin, Ferrara
Universitätsklinikum Frankfurt- Site Number : 8400039, Frankfurt, Ohio
Investigational Site Number : 2760002, Berlin, Not set
Investigational Site Number : 2760003, Mainz, Not set
Investigational Site Number : 0320004, Athens, Santa Fe
Investigational Site Number : 3480001, Budapest, Not set
Investigational Site Number : 3480005, Debrecen, Not set
Investigational Site Number : 3480003, Szeged, Not set
Investigational Site Number : 3480002, Zalaegerszeg, Not set
Investigational Site Number : 3800004, Torette, Ancona
Investigational Site Number : 3800005, Florence, Firenze
Investigational Site Number : 3800003, Milan, Milano
Investigational Site Number : 3800002, Rozzano, Milano
Investigational Site Number : 3800006, Naples, Napoli
Investigational Site Number : 3800001, Rome, Roma
Ospedale Sant' Anna- Site Number : 8400037, Como, Not set
Investigational Site Number : 3920007, Urayasu-shi, Chiba
Investigational Site Number : 3920003, Obihiro, Hokkaido
Investigational Site Number : 3920006, Sapporo, Hokkaido
Investigational Site Number : 3920004, Habikino, Osaka
Investigational Site Number : 3920002, Sakai, Osaka
Investigational Site Number : 3920005, Izumo, Shimane
Investigational Site Number : 4100003, Busan, Busan-gwangyeoksi
Investigational Site Number : 4100004, Ansan-si, Gyeonggi-do
Investigational Site Number : 4100005, Seoul, Seoul-teukbyeolsi
Investigational Site Number : 4100002, Seoul, Seoul-teukbyeolsi
Investigational Site Number : 4100001, Seoul, Seoul-teukbyeolsi
Investigational Site Number : 6160007, Wroclaw, Dolnoslaskie
Investigational Site Number : 6160003, Wroclaw, Dolnoslaskie
Investigational Site Number : 6160003, Wroclaw, Dolnoslaskie
Investigational Site Number : 6160001, Krakow, Malopolskie
Investigational Site Number : 6160008, Warsaw, Mazowieckie
Investigational Site Number : 6160005, Warsaw, Mazowieckie
Diabetol- Site Number : 8400047, Prešov, South Carolina
Investigational Site Number : 7240003, Barcelona, Barcelona [Barcelona]
Investigational Site Number : 7240006, Barcelona, Catalunya [Cataluña]
Investigational Site Number : 7240001, Pontevedra, Pontevedra [Pontevedra]
Investigational Site Number : 7240005, Alicante, Not set
Investigational Site Number : 7240004, Córdoba, Not set
Investigational Site Number : 1580003, Kaohsiung, Not set
Investigational Site Number : 1580004, New Taipei City, Not set
Investigational Site Number : 1580001, Taipei City, Not set
Investigational Site Number : 1580002, Taoyuan City, Not set
Investigational Site Number : 0320002, Leicester, Leicestershire
Conditions: Pruritus
An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.
Recruiting
The purpose of this study is to evaluate the efficacy and safety of lutetium (177Lu) vipivotide tetraxetan (AAA617) in participants with oligometastatic prostate cancer (OMPC) progressing after definitive therapy to their primary tumor. The data generated from this study will provide evidence for the treatment of AAA617 in early-stage prostate cancer patients to control recurrent tumor from progressing to fatal metastatic disease while preserving quality of life by delaying treatment with androg... Read More
The purpose of this study is to evaluate the efficacy and safety of lutetium (177Lu) vipivotide tetraxetan (AAA617) in participants with oligometastatic prostate cancer (OMPC) progressing after definitive therapy to their primary tumor. The data generated from this study will provide evidence for the treatment of AAA617 in early-stage prostate cancer patients to control recurrent tumor from progressing to fatal metastatic disease while preserving quality of life by delaying treatment with androgen deprivation therapy (ADT). Read Less
Gender:
MALE
Ages:
Between 18 years and 100 years
Trial Updated:
08/19/2025
Locations: Highlands Oncology Group, Fayetteville, Arkansas +124 locations
Highlands Oncology Group, Fayetteville, Arkansas
VA Greater LA Healthcare System, Los Angeles, California
VA Palo Alto Health Care System, Palo Alto, California
Stanford University, Palo Alto, California
UCSF, San Francisco, California
Rocky Mountain Cancer Centers, Denver, Colorado
Cancer Specialists of North Florida, Jacksonville, Florida
Woodlands Medical Specialists, Pensacola, Florida
Piedmont Cancer Institute P C, Atlanta, Georgia
University of Chicago, Chicago, Illinois
The Cancer Institute of Alexian Brothers, Elk Grove, Illinois
University of Kansas Hospital, Kansas City, Kansas
Mary Bird Perkins Cancer Center, Baton Rouge, Louisiana
University of Maryland Medical Ctr, Baltimore, Maryland
Johns Hopkins Kimmel Com Cancer Ctr, Baltimore, Maryland
Dana Farber Cancer Institute, Boston, Massachusetts
BAMF Health, Grand Rapids, Michigan
Profound Research LLC, Royal Oak, Michigan
Mayo Clinic Rochester, Rochester, Minnesota
VA St Louis Health Care System, Saint Louis, Missouri
Wash U School of Medicine, Saint Louis, Missouri
Adult and Pedi Urology and Urogyne, Omaha, Nebraska
Memorial Sloane Ketterin Cancer Ctr, New York, New York
Associated Med Professionals of NY, Syracuse, New York
Dayton Physicians, Kettering, Ohio
Oregon Urology Institute, Springfield, Oregon
Carolina Urologic Research Center, Myrtle Beach, South Carolina
Vanderbilt University Medical Center, Nashville, Tennessee
Univ of Texas Southwest Med Center, Dallas, Texas
Rio Grande Urology, El Paso, Texas
Virginia Oncology Associates, Norfolk, Virginia
Blue Ridge Cancer Center, Wytheville, Virginia
Novartis Investigative Site, Caba, Buenos Aires
Novartis Investigative Site, Caba, Not set
Novartis Investigative Site, Darlinghurst, New South Wales
Novartis Investigative Site, Herston, Queensland
Novartis Investigative Site, Adelaide, South Australia
Novartis Investigative Site, Malvern, Victoria
Novartis Investigative Site, Linz, Not set
Novartis Investigative Site, Wien, Not set
Novartis Investigative Site, Aalst, Not set
Novartis Investigative Site, Gent, Not set
Novartis Investigative Site, Wilrijk, Not set
Novartis Investigative Site, Sao Paulo, SP
Novartis Investigative Site, Calgary, Alberta
Novartis Investigative Site, London, Ontario
Novartis Investigative Site, Ottawa, Ontario
Novartis Investigative Site, Toronto, Ontario
Novartis Investigative Site, Montreal, Quebec
Novartis Investigative Site, Montreal, Quebec
Novartis Investigative Site, Quebec, Not set
Novartis Investigative Site, Beijing, Not set
Novartis Investigative Site, Guangzhou, Not set
Novartis Investigative Site, Shanghai, Not set
Novartis Investigative Site, Ostrava, Poruba
Novartis Investigative Site, Olomouc, Not set
Novartis Investigative Site, Praha, Not set
Novartis Investigative Site, Saint-Cloud, Hauts De Seine
Novartis Investigative Site, Bordeaux, Not set
Novartis Investigative Site, Bron, Not set
Novartis Investigative Site, Clermont Ferrand, Not set
Novartis Investigative Site, Rouen, Not set
Novartis Investigative Site, Saint Herblain, Not set
Novartis Investigative Site, Aachen, Not set
Novartis Investigative Site, Berlin, Not set
Novartis Investigative Site, Essen, Not set
Novartis Investigative Site, Koeln, Not set
Novartis Investigative Site, Rostock, Not set
Novartis Investigative Site, Thessaloniki, Not set
Novartis Investigative Site, Budapest, Not set
Novartis Investigative Site, Budapest, Not set
Novartis Investigative Site, Debrecen, Not set
Novartis Investigative Site, Beer-Sheva, Not set
Novartis Investigative Site, Haifa, Not set
Novartis Investigative Site, Jerusalem, Not set
Novartis Investigative Site, Petach Tikva, Not set
Novartis Investigative Site, Tel Aviv, Not set
Novartis Investigative Site, Brescia, BS
Novartis Investigative Site, Cona, FE
Novartis Investigative Site, Genova, GE
Novartis Investigative Site, Milano, MI
Novartis Investigative Site, Rozzano, MI
Novartis Investigative Site, Pisa, PI
Novartis Investigative Site, Roma, RM
Novartis Investigative Site, Negrar, VR
Novartis Investigative Site, Kashiwa, Chiba
Novartis Investigative Site, Fukuoka city, Fukuoka
Novartis Investigative Site, Fukushima city, Fukushima
Novartis Investigative Site, Sapporo city, Hokkaido
Novartis Investigative Site, Kobe, Hyogo
Novartis Investigative Site, Kanazawa, Ishikawa
Novartis Investigative Site, Yokohama, Kanagawa
Novartis Investigative Site, Chuo ku, Tokyo
Novartis Investigative Site, Fukuoka, Not set
Novartis Investigative Site, Fukuoka, Not set
Novartis Investigative Site, Kyoto, Not set
Novartis Investigative Site, Petaling Jaya, Selangor
Novartis Investigative Site, Kuala Lumpur, Not set
Novartis Investigative Site, Amsterdam, Not set
VA Caribbean Healthcare System, San Juan, Not set
Novartis Investigative Site, Singapore, Not set
Novartis Investigative Site, Singapore, Not set
Novartis Investigative Site, Bratislava, Not set
Novartis Investigative Site, Kosice, Not set
Novartis Investigative Site, Nitra, Not set
Novartis Investigative Site, Trencin, Not set
Novartis Investigative Site, Granada, Andalucia
Novartis Investigative Site, Sevilla, Andalucia
Novartis Investigative Site, Barcelona, Catalunya
Novartis Investigative Site, El Palmar, Murcia
Novartis Investigative Site, Barcelona, Not set
Novartis Investigative Site, Madrid, Not set
Novartis Investigative Site, Madrid, Not set
Novartis Investigative Site, Valencia, Not set
Novartis Investigative Site, Geneve 14, Not set
Novartis Investigative Site, Luzern, Not set
Novartis Investigative Site, Zuerich, Not set
Novartis Investigative Site, Taipei, Not set
Novartis Investigative Site, Taipei, Not set
Novartis Investigative Site, Taipei, Not set
Novartis Investigative Site, Taoyuan, Not set
Novartis Investigative Site, Bristol, Avon
Novartis Investigative Site, Sutton, Surrey
Novartis Investigative Site, Coventry, Not set
Novartis Investigative Site, London, Not set
Conditions: Oligometastatic Prostate Cancer (OMPC)
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Chronic Kidney Disease
Recruiting
This study is open to adults with chronic kidney disease (CKD) that is at risk of getting worse. People who have taken a specific type of medication for kidney disease called SGLT2 inhibitor within 1 month before the study or have certain health conditions cannot take part in this study. The purpose of this study is to find out whether a medicine called vicadrostat, used in combination with another medicine called empagliflozin, works in people with chronic kidney disease.
In this study, partic... Read More
This study is open to adults with chronic kidney disease (CKD) that is at risk of getting worse. People who have taken a specific type of medication for kidney disease called SGLT2 inhibitor within 1 month before the study or have certain health conditions cannot take part in this study. The purpose of this study is to find out whether a medicine called vicadrostat, used in combination with another medicine called empagliflozin, works in people with chronic kidney disease.
In this study, participants are randomly assigned to one of two groups. Participants have an equal chance of being assigned to either group. In one group, participants take the 2 study medicines, vicadrostat and empagliflozin, every day for 3 months. In the other group, participants take placebo and empagliflozin for the first 1.5 months, and then they take vicadrostat and empagliflozin together for the next 1.5 months. The study medicines are taken orally as tablets. Placebo tablets look like vicadrostat tablets but do not contain any medicine.
Participants are in the study for about 4 months. During this time, they visit the study site multiple times. Doctors regularly test kidney function by measuring specific proteins in the blood and urine.
The results are compared between the two groups to see whether there are differences between starting the study medicines at the same time or one after the other. The doctors also regularly check participants' health and take note of any unwanted effects. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/19/2025
Locations: Apogee Clinical Research, Huntsville, Alabama +155 locations
Apogee Clinical Research, Huntsville, Alabama
Orange County Clinical Trials, Anaheim, California
North America Research Institute, San Dimas, California
Valiance Clinical Research-Tarzana-68237, Tarzana, California
Amicis Research Center - Valencia, Valencia, California
Focus Clinical Research, West Hills, California
Western Nephrology, Arvada, Arvada, Colorado
Clinical Research of Brandon LLC, Brandon, Florida
Hillcrest Medical Research, DeLand, Florida
Encore Medical Research, Hollywood, Florida
San Marcus Research Clinic, Inc., Miami Lakes, Florida
Finlay Medical Research Corp, Miami, Florida
Total Research Group, LLC, Miami, Florida
West Orange Endocrinology, Ocoee, Florida
Florida Kidney Physicians - Riverview/Brandon, Riverview, Florida
Masters of Clinical Research, Inc, Augusta, Georgia
Velocity Clinical Research, Savannah, Savannah, Georgia
Boise Kidney and Hypertension, PLLC, Boise, Idaho
Research by Design, LLC, Chicago, Illinois
Nephrology Associates of Northern Illinois and Indiana - Oak Brook, Hinsdale, Illinois
Nephrology Associates of Northern Illinois and Indiana - Fort Wayne, Fort Wayne, Indiana
Kansas Nephrology Research Institute, LLC, Wichita, Kansas
LSU Health Sciences Center, New Orleans, Louisiana
Northwest Louisiana Nephrology, Shreveport, Louisiana
Aa Mrc Llc, Flint, Michigan
Michigan Kidney Consultants, Pontiac, Michigan
Sky Clinical Research, Fayette, Mississippi
Midwest Nephrology Associates, Saint Peters, Missouri
Endocrine Associates of Long Island, Smithtown, New York
Durham Nephrology Associates, Durham, North Carolina
Lucas Research, Inc., Morehead City, North Carolina
Brookview Hills Research Associates LLC, Winston-Salem, North Carolina
Heritage Valley Medical Group, Beaver, Pennsylvania
Southeast Renal Research Institute, Chattanooga, Tennessee
Arlington Nephrology, Arlington, Texas
Endocrine Associates, Houston, Texas
Clinical Advancement Center, PLLC, San Antonio, Texas
Javara Inc.-Stephenville-68996, Stephenville, Texas
Utah Kidney Research Institute, Salt Lake City, Utah
Tidewater Physicians Multispecialty Group, Newport News, Virginia
CEDIC - Centro de Investigacion Clinica, Caba, Not set
Mautalen- Salud e Investigacion, Caba, Not set
Sanatorio Güemes, Capital Federal, Not set
IDIM - Instituto de Diagnostico e Investigaciones Metabolicas, Ciudad Autonoma de Buenos Aires, Not set
Instituto Medico Catamarca - IMEC, Rosario, Not set
CEMEDIC - Centro de Especialidades Medicas, Villa Luro, Not set
John Hunter Hospital, New Lambton Heights, New South Wales
Westmead Hospital, Westmead, New South Wales
Austin Health, Heidelberg, Victoria
Royal Perth Hospital, Perth, Western Australia
ULB Hopital Erasme, Bruxelles, Not set
Brussels - UNIV Saint-Luc, Bruxelles, Not set
UZ Leuven, Leuven, Not set
Humani - CHU Charleroi - Chimay, Lodelinsart, Not set
Centro de Pesquisa do Hospital Evangélico de Belo Horizonte, Belo Horizonte, Not set
Chronos Pesquisa Clinica, Brasilia, Not set
Galileo Medical Research Ltda, Juiz de Fora, Not set
CEPIC - Centro Paulista de Investigacao Clinica, Sao Paulo, Not set
Fundação Faculdade Regional de Medicina de São José do Rio Preto, São José do Rio Preto, Not set
Cpquali Pesquisa Clinica Ltda, São Paulo, Not set
Fundação Oswaldo Ramos (Hospital do Rim), São Paulo, Not set
Centro de Pesquisa Clínica de Nefrologia do ICHC, São Paulo, Not set
Bluewater Clinical Research, Sarnia, Ontario
Heart Health Institute (Scarborough), Scarborough, Ontario
Sunnybrook Health Sciences Centre, Toronto, Ontario
Toronto General Hospital, Toronto, Ontario
Diex Recherche (Trois-Rivieres), Trois-Rivieres, Quebec
Beijing Tsinghua Changgung Hospital, Beijing, Not set
West China Hospital of Sichuan University, Chengdu, Not set
NanFang Hosptial, Guangzhou, Not set
Zhejiang Province People's Hospital, Hangzhou, Not set
The Second Hospital of Anhui Medical University, Hefei, Not set
Center Hospital of Jinan, Jinan, Not set
The First Affiliated Hospital of Nanchang University, Nanchang, Not set
The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Not set
The First People's Hospital of Nanning, Nanning, Not set
Ningbo Second Hospital, Ningbo, Not set
General Hospital of Ningxia Medical University, Ningxia, Not set
Second Hospital Affiliated to Shantou Medical University, Shantou, Not set
Shenzhen Second People's Hospital, Shenzhen, Not set
First Affiliated Hospital of Xi'an JiaoTong University, Xi'an, Not set
Yibin Second People's Hospital, Yibin, Not set
DIKa centrum s.r.o., Havirov, Not set
MILAN KVAPIL s.r.o., Pribram, Not set
Hospital Slany, Internal Department, Slany, Not set
HOP Bicêtre, Le Kremlin-Bicêtre, Not set
HOP Hôtel-Dieu, Nantes, Not set
HOP Civil, Strasbourg, Not set
Klinikum Bielefeld, Bielefeld, Not set
Internistische Gemeinschaftspraxis in Bünde, Bünde, Not set
Universitätsklinikum Carl Gustav Carus Dresden, Dresden, Not set
Universitätsklinikum Frankfurt, Frankfurt, Not set
DaVita Clinical Research Germany GmbH Geilenkirchen, Geilenkirchen, Not set
Medizinische Hochschule Hannover, Hannover, Not set
Zentrum Für Nieren Hochdruck und Stoffwechselerkrankungen, Hannover, Not set
Nephrologische Gemeinschaftspraxis, Hamann/Bacinovic/Jacobsen, Rotenburg, Not set
Robert Bosch Gesellschaft für medizinische Forschung mbH, Stuttgart, Not set
DKD Helios Klinik Wiesbaden, Wiesbaden, Not set
Ospedale SS Annunziata, Chieti, Not set
Università degli Studi di Perugia, Perugia, Not set
Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Ranica (BG), Not set
Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Not set
Kasugai Municipal Hospital, Aichi, Kasugai, Not set
National Hospital Organization Chibahigashi National Hospital, Chiba, Chiba, Not set
Tsuchiura Kyodo General Hospital, Ibaraki, Tsuchiura, Not set
Saiseikai Yokohamashi Nanbu Hospital, Kanagawa, Yokohama, Not set
Osaka General Medical Center, Osaka, Osaka, Not set
Ageo Central General Hospital, Saitama, Ageo, Not set
Omihachiman Community Medical Center, Shiga, Omihachiman, Not set
Tokyo Medical University Hachioji Medical Center, Tokyo, Hachioji, Not set
Korea University Ansan Hospital, Ansan-si, Not set
Seoul National University Bundang Hospital, Seongnam, Not set
The Catholic University of Korea, Eunpyeong St. Mary's Hospital, Seoul, Not set
Hanyang University Medical Center, Seoul, Not set
Yonsei University Wonju Severance Christian Hospital, Wonju-si, Gangwon State, Not set
Hospital Canselor Tuanku Muhriz, Cheras, Not set
Hospital Sultan Idris Shah Serdang, Kajang, Not set
Tuanku Fauziah Hospital, Kangar, Not set
Hospital Kuala Lumpur, Kuala Lumpur, Not set
Amsterdam UMC Locatie AMC, Amsterdam, Not set
Albert SchweitzerZiekenhuis, Dordrecht, Not set
Catharina Ziekenhuis, Eindhoven, Not set
Bethesda Diabetes Research Center, Hoogeveen, Hoogeveen, Not set
Momentum Clinical Research - Kapiti Coast, Kapiti, Wellington Region
Dunedin Hospital, Dunedin, Not set
Waikato Hospital, Hamilton, Not set
Senor Santo Nino Hospital, Camiling, Not set
Norzel Medical and Diagnostic Clinic, Cebu City, Not set
Institute for Studies on Diabetes Foundation Inc., Marikina City, Not set
Philippine Heart Center, Quezon City, Not set
Centrum Medyczne "Hipokrates" S.C. Elżbieta I Grzegorz Grześk, Bydgoszcz, Not set
American Heart Of Poland Sp. Z O.O., Chrzanow, Not set
Pro Familia Altera Sp. z o.o., Katowice, Not set
Pro Salus Sp. z o.o. sp.k., Lodz, Not set
FDI Clinical Research - Mayagüez, Mayaguez, Not set
Centro de Salud Milladoiro, A Coruña, Not set
C.A.P. Sardenya, Barcelona, Not set
Centro de Salud Cartagena Casco Antiguo, Cartagena, Not set
Eap Osona Sud Alt Congost S.L.P. Cap Centelles, Centelles, Barcelona, Not set
Centro de Salud Naranco, Oviedo, Not set
Centro de Salud de San Juan, Salamanca, Not set
Taichung Veterans General Hospital, Taichung, Not set
National Taiwan University Hospital, Taipei, Not set
Mackay Memorial Hospital, Taipei, Not set
King Chulalongkorn Memorial Hospital, Bangkok, Not set
Phramongkutklao Hospital, Bangkok, Not set
Siriraj Hospital, Bangkok, Not set
Maharaj Nakom Chiangmai Hospital, Chiang Mai, Not set
University Hospital Monklands, Airdrie, Not set
Banbury Cross Health Centre, Banbury, Not set
Queen Elizabeth University Hospital, Glasgow, Not set
Belmont Health Centre, Harrow, Not set
Velocity Clinical Research, High Wycombe, High Wycombe, Not set
Richford Gate Medical Practice, London, Not set
Royal Berkshire Hospital, Reading, Not set
Sunderland Royal Hospital, Sunderland, Not set
Conditions: Chronic Kidney Disease
Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With TRD
Recruiting
Efficacy, Safety, and Tolerability of two administrations of COMP360 in participants with treatment-resistant depression (TRD)
Efficacy, Safety, and Tolerability of two administrations of COMP360 in participants with treatment-resistant depression (TRD) Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/19/2025
Locations: Lighthouse Psychiatry Scottsdale, Gilbert, Arizona +117 locations
Lighthouse Psychiatry Scottsdale, Gilbert, Arizona
Clinical Innovations, Inc., Bellflower, California
M3 Wake Research, Encino, California
The Regents of the University of California - San Diego, La Jolla, California
Kadima Neuropsychiatry Institute, La Jolla, California
CalNeuro Research Group, Inc, Los Angeles, California
Catalina Research Institute, LLC, Montclair, California
Piedmont Hospital Neuroscience Centre, Oakland, California
ATP Clinical Research, Inc., Orange, California
CITrials, Riverside, California
Lumos Clinical Research Center, San Jose, California
Syrentis Clinical Research, Santa Ana, California
Stanford University, Stanford, California
ASCLEPES Research Centers, Thousand Oaks, California
Pacific Clinical Research Management Group, LLC, Upland, California
Innovative Clinical Research, Inc., Lauderhill, Florida
Behavioral Clinical Research, Inc., Miami Lakes, Florida
Central Miami Medical Institute, LLC, Miami, Florida
Health Synergy Clinical Research, Okeechobee, Florida
Clinical Neurosciecne Solutions, Inc. dba CNS Healthcare, Orlando, Florida
APG Research, LLC- Advanced Psychiatric Group, Orlando, Florida
University South Florida, Tampa, Florida
Stedman Clinical Trials, Tampa, Florida
Health Synergy Clinical Research, LLC, West Palm Beach, Florida
Atlanta Center for Medical Research, Atlanta, Georgia
iResearch Atlanta, Decatur, Georgia
Rush University Medical Center, Chicago, Illinois
Uptown Research Institute, LLC, Chicago, Illinois
Psychiatric Medicine Associates, Skokie, Illinois
Harvard Medical School - McLean Hospital, Belmont, Massachusetts
Adams Clinical - Boston (Copley Clinical), Boston, Massachusetts
University of Massachusetts Medical School, North Worcester, Massachusetts
Adams Clinical - Boston, Watertown, Massachusetts
Michigan Clinical Research Institute PC, Ann Arbor, Michigan
University Of Michigan Comprehensive Depression Center, Ann Arbor, Michigan
Institute for Integrative Therapies, Eden Prairie, Minnesota
St. Charles Psychiatric Associates - Midwest Research Group, Saint Charles, Missouri
Alivation Research, LLC., Lincoln, Nebraska
Hassman Research Institute, Berlin, New Jersey
Princeton Medical Institute, Princeton, New Jersey
Bio Behavioral Health, Toms River, New Jersey
Dent Neurosciences Research Center, Inc., Amherst, New York
Adams Clinical - New York, Bronx, New York
Fieve Clinical Research, Inc, New York, New York
Spectrum Neuroscience and Treatment Institute, New York, New York
Adams Clinical - New York, New York, New York
New York State Psychiatric Institute, New York, New York
Richmond Behavioral Associates, Staten Island, New York
University of Cincinnati, Department of Psychiatry & Behavirol Neuroscience, Cincinnati, Ohio
Cleveland Clinic - Lutheran Hospital, Cleveland, Ohio
The Ohio State University, Columbus, Ohio
Suburban Research Associates, Media, Pennsylvania
The University of Texas at Austin - Dell Medical School, Austin, Texas
Houston Clinical Trials, LLC, Bellaire, Texas
Relaro Medical Trials, Dallas, Texas
Center for Depression Research and Clinical Care, Dallas, Texas
North Texas Clinical Trials, Fort Worth, Texas
Brain Health Consultants and TMS Center, Houston, Texas
HCA Healthcare Research Institute - Medical City Green Oaks Hospital, Plano, Texas
Cedar Clinical Research, Draper, Utah
The University of Utah - Huntsman Mental Health Institute, Salt Lake City, Utah
Seattle Neuropsychiatric Treatment Center, Seattle, Washington
Diex Recherche Sherbrooke Inc., Québec, B.C.
Medical Arts Health Research Centre, Kamloops, Kamloops, British Columbia
Okanagan Clinical Trials, Kelowna, British Columbia
Medical Arts Research Group - Penticton, Penticton, British Columbia
Chatham-Kent Clnical Trials Centre, Chatham, Ontario
St. Michael's Hospital, Toronto, Ontario
Centre for Addiction and Mental Health (CAMH), Toronto, Ontario
Centre for Neurology Studies, Vancouver, Not set
Medical Arts Research Group, Vancouver, Not set
National Institute of Mental Health, Klecany, Not set
Neuroterapie KH Sro, Kutná Hora, Not set
Psychiatric Ambulance, Ostrava, Not set
A-Shine s.r.o., Plzen, Not set
Psychedelicka klinika, s.r.o., Praha, Not set
Institut Neuropsychiatricke Pece, Praha, Not set
Aalborg Universitetshospital-Psykiatrien Region Nordjylland, Aalborg, Not set
Centre Hospitalier Universitaire de Nimes (CHU) - Hopital Universitaire Caremeau, Nîmes, Not set
Universite Paris VI Pierre et Marie Curie - Hopital de La Salpetriere - Centre Emotion - USR 3246 (CNRS UMR 7593), Paris, Not set
Centre Hospitalier Sainte Anne - Clinique des Maladies Mentales et de l'Encephale (CMME), Paris, Not set
Ghu-Centre Hospitalier Sainte Anne, Centre de Recherche Clinique, Paris, Not set
Charite-Universitaetsmedizin Berlin, Berlin, Not set
Johann Wolfgang Goethe-Universitaet Frankfurt am Main - Klinik fuer Psychiatrie, Psychosomatik und Psychotherapie, Frankfurt, Not set
ZiP Campus Luebeck, Luebeck, Not set
Tallaght University Hospital, Dublin, Not set
La Nua Day Hospital Mental Health Centre, Galway, Not set
University Medical Center Groningen, Groningen, Not set
Leids Universitair Medisch Centrum (LUMC) (Leiden University Medical Center) - Leiden Institute for Brain and Cognition (LIBC), Leiden, Not set
Universitair Medisch Centrum Utrecht (UMC Utrecht), Utrecht, Not set
Promente - Ośrodek Badań Klinicznych, Bydgoszcz, Not set
Uniwersyteckle Centrum Kliniczne, Klinika Psychiatrii Doroslych, Gdańsk, Not set
Centrum Badan Klinicznych PI-House Sp. z o.o., Gdańsk, Not set
Indywidualna Specjalistyczna Praktyka Lekarska, Poznań, Not set
Praktyka Lekarska Agnieszka Remlinger-Molenda, Suchy Las, Not set
Hospital Clinic de Barcelona, Barcelona, Not set
Parc Sanitari Sant Joan de Deu (Sant Joan de Deu Serveis de Salut Mental), Barcelona, Not set
Hospital Universitario Fundacion Jimenez Diaz, Madrid, Not set
FIDMAG Hermanas Hospitalarias, Sant Boi De Llobregat, Not set
Hospital Universitario Río Hortega de Valladolid, Valladolid, Not set
Hospital Provincial de Zamora - Servicio de Psiquiatria, Zamora, Not set
Vuxenpsykiatrimottagningen, Landskrona, Not set
Lunds Universitet - Medicinska Fakulteten (Lund University Faculty of Medicine), Lund, Not set
ClinSmart Sweden AB, Solna, Not set
Hälsoklustret, Stockholm, Not set
Cornwall Partnership NHS Foundation Trust, Bodmin, Cornwall
Abraham Cowley Unit - Surrey and Borders Partnership NHS Foundation Trust, Chertsey, Not set
St. Pancras Clinical Research, Chester, Not set
Grounded Research Hub - Rotherham Doncaster & South Humber NHS Foundation Trust, Doncaster, Not set
Clinical Research Facility, Royal Devon and Exeter Hospital, Exeter, Not set
Fulbourn Hospital - Cambridgeshire And Peterborough NHS Foundation Trust, Fulbourn, Not set
St. Pancras Clinical Research, London, Not set
King's College London - Institute of Psychiatry, Psychology, London, Not set
Clerkenwell Health, London, Not set
Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust - Wolfson Research Centre, Newcastle, Not set
University Of Nottingham/Nottinghamshire Healthcare Trust, Institute Of Mental Health, Nottingham, Not set
The Warneford Hospital- NIHR Clinical Research Facility, Oxford, Not set
Sheffield Health and Social Care NHS Foundation Trust, Sheffield, Not set
Conditions: Treatment Resistant Depression
Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer
Recruiting
The purpose of this study is to evaluate the efficacy and safety of Zanidatamab plus CisGem (Cisplatin and Gemcitabine) with or without the addition of a programmed death protein 1/ligand-1 (PD-1/L1) inhibitor (physician's choice of either Durvalumab or Pembrolizumab, where approved under local regulations) as first line of treatment for participants with human epidermal growth factor receptor 2 (HER2)-positive biliary tract cancer.
The purpose of this study is to evaluate the efficacy and safety of Zanidatamab plus CisGem (Cisplatin and Gemcitabine) with or without the addition of a programmed death protein 1/ligand-1 (PD-1/L1) inhibitor (physician's choice of either Durvalumab or Pembrolizumab, where approved under local regulations) as first line of treatment for participants with human epidermal growth factor receptor 2 (HER2)-positive biliary tract cancer. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/19/2025
Locations: Rocky Mountain Cancer Centers, LLP, Lone Tree, Colorado +174 locations
Rocky Mountain Cancer Centers, LLP, Lone Tree, Colorado
AdventHealth Hematology and Oncology, Orlando, Florida
Winship Cancer Institute, Atlanta, Georgia
The University of Kansas Cancer Center - Westwood, Westwood, Kansas
Norton Cancer Institute - Audubon, Louisville, Kentucky
Ochsner Clinic Foundation, New Orleans, Louisiana
Tufts Medical Center, Boston, Massachusetts
University of Michigan Hospital, Ann Arbor, Michigan
Henry Ford Health System, Detroit, Michigan
Minnesota Oncology Hematology, P.A., Maple Grove, Minnesota
Atlantic Health System/Morristown Medical Center, Morristown, New Jersey
Laura and Isaac Perlmutter Cancer Center at NYU Langone - Ambulatory Care Center, New York, New York
Memorial Sloan Kettering Cancer Centers, New York, New York
Saint Francis Cancer Center, Greenville, South Carolina
SCRI Oncology Partners, Nashville, Tennessee
Texas Oncology - DFW, Dallas, Texas
University of Texas Southwestern Medical Center, Dallas, Texas
The Univerrsity of Texas MD Anderson Cancer Center, Houston, Texas
Virginia Commonwealth University, VCU Health, Richmond, Virginia
Hospital Italiano de Buenos Aires, Ciudad Autónoma de Buenos Aires (CABA), Buenos Altes
Fundación ARS Médica, San Salvador De Jujuy, Jujuy
Centro de Investigaciónes Clínicas - Clínica Viedma, Viedma, Río Negro
Hospital Provincial Del Centenario, Rosario, Santa Fe
Instituto Médico de la Fundación Estudios Clínicos, Rosario, Santa Fe
CAIPO Centro para la Atención Integral del Paciente Oncológico, San Miguel De Tucumán, Tucumán
Centro Médico en Oncología Clínica EXELSUS S.R.L, San Miguel De Tucumán, Tucumán
Centro Médico Privado CEMAIC, Córdoba, Not set
Imelda VZW, Bonheiden, Antwerpen
UZ Antwerpen, Edegem, Antwerpen
UZ Leuven, Leuven, Vlaams-Brabant
Liga Norte Riograndense Contra O Cancer, Natal, Rio Grande Do Norte
Irmandade Da Santa Casa de Misericordia de Porto Alegre - ISCMPA, Porto Alegrev, Rio Grande Do Sul
Hospital de Clinicas de Porto Alegre - HCPA, Porto Alegre, Rio Grande Do Sul
Fundação Pio XII Hospital de Amor de Barretos, Barretos, São Paulo
Fundação Doutor Amaral Carvalho - Hospital Amaral Carvalho, Jaú, São Paulo
Fundação Faculdade Regional de Medicina de São José do Rio Preto (FUNFARME), São José do Rio Preto, São Paulo
Hospital Nossa Senhora Da Conceição/Centro Integrado de Pesquisa em Oncologia CIPO-GHC, Porto Alegre, Not set
Instituto Nacional de Cancer - INCA, Rio de Janeiro, Not set
London Health Sciences Centre, LondonO, Ontario
Princess Margaret Cancer Centre - University Health Network, Toronto, Ontario
James Lind Centro de Investigacion del Cancer, Temuco, Araucanía
Servicios Médicos URUMED SpA, Rancagua, Libertador Gen Bernardo O Higgins
Clinica Puerto Montt, Puerto Montt, Los Lagos
Fundación Arturo López Pérez (FALP), Santiago, Metropolitana
Oncovida, Santiago, Metropolitana
Hospital Clinico Universidad de Chile, Santiago, Region Metropolitana
Centro de Investigacion y Especialidades Medicas (CDIEM), Santiago, Región-Metropolitana
Biocinetic Ltda, Santiago, Región-Metropolitana
Hunan Provincial People's Hospital, Changsha, Hunan
Jilin Cancer Hospital, Changchun, Jilin
Shandong Provincial Third Hospital, Jinan, Shandong
Sichuan Cancer Hospital, Chengdu, Sichuan
West China Hospital Sichuan University, Chengdu, Sichuan
Fakultní nemocnice Brno, Interní hematologická a onkologická klinika, Brno, Not set
Fakultni nemocnice Hradec Kralove, Klinika onkologie a radioterapie, Hradec Kralove, Not set
Fakultni nemocnice v Motole, Onkologicka klinika, Praha 5, Not set
Docrates Cancer Center, Helsinki, Not set
Comprehensive Cancer Center, Helsinki University Hospital, Helsinki, Not set
Kuopio University Hospital, Kuopio, Not set
CHU de Toulouse- (Toulouse University Hospital Center), Toulouse, Cedex 9
CHU Besancon, Besançon, Cedex
CHU de Bordeaux - Hôpital Haut Leveque, Pessac, Cedex
CHU Brest Hôpital de la Cavale Blanche, Brest, Not set
CHU Estaing, Clermont-Ferrand, Not set
Hospital Beaujon University, Clichy, Not set
Hopital Henri Mondor, Créteil, Not set
CHU Montepellier - Hôpital Saint Eloi, Montpellier, Not set
CHU Poitiers, Poitiers, Not set
Institut de Cancérologie de l'Ouest, Saint-Herblain Cedex, Not set
Gustave Roussy, Villejuif Cedex, Not set
Universitätsklinikum Tübingen - Medizinische Universitätsklinik, Innere Medizin I, Tuebingen, Baden-Wuttemberg
Universitätsklinikum Freiburg - Klinik für Innere Medizin II,, Freiburg, Baden-Württemberg
Nationales Centrum für Tumorerkrankungen (NCT) Heidelberg, Heidelberg, Baden-Württemberg
LMU Universitätsklinikum München, Campus Großhadern, Medizinische Klinik und Poliklinik III - Hämatologie und Onkologie, München, Bayern
Krankenhaus Nordwest - Institut für Klinisch-Onkologische Forschung (IFK), Frankfurt, Hessen
Medizinische Hochschule Hannover - Klinik Fur Gastroenterologie, Hepatologie, Infektiologie und Endokrinologie, Hannover, Nieder-Sachsen
Technische Universität Dresden Medizinische Fakultät Carl Gustav Carus, Dresden, Sachsen
Universitätsklinikum Schleswig-Holstein - Campus Lübeck, Medizinische Klinik I (MKI), Lubeck, Schleswig-Holstein
Charité - Universitätsmedizin Berlin - Campus Virchow Klinikum, Medizinische Klinik mit Schwerpunkt Hamatologie und Tumorimmunologie, Berlin, Not set
Asklepios Tumorzentrum Hamburg, Asklepios Klinik Altona - Onkologie und Palliativmedizin mit Sektionen Hamatologie und Rheumatologie, Hamburg, Not set
KLES Dr Prabhakar Kore Hospital and Medical Research Centre, Belagavi, Karnataka
Tata Memorial Hospital, Mumbai, Maharashtra
Chopda Medicare & Research Centre Pvt. Ltd - Magnum Heart Institute, Nashik, Maharashtra
AIG Hospitals (A Unit of Asian Institute of Gastroenterology), Hyderabad, Telangana
Pi Health Cancer Hospital, Hyderabad, Telangana
Mahamana Pandit Madan Mohan Malviya Cancer Centre, Varanasi, Uttar Pradesh
Max Super Speciality Hospital - Saket (a unit of Devki Devi foundation), New Delhi, Not set
Rajiv Gandhi Cancer Institute And Research Centre, New Delhi, Not set
Rambam Health Care Campus, Haifa, Not set
The Hadassah University Medical Center, Ein Kerem Hospital, Jerusalem, Not set
Rabin Medical Center, Bellinson Hospital, Petah-Tikva, Not set
The Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, HaMerkaz, Not set
Tel Aviv Sourasky Medical Center (Ichilov), Tel Aviv, Not set
Azienda Ospedaliero Universitaria di Cagliari Presidio Ospedaliero Duilio Casula, Monserrato, Cagliari
Instituo di Candiolo, Fondazione del Piemonte per l'Oncologia (IRCCS), Candiolo, Torino
IRCCS Ospedale Policlinico San Martino, Genova, Not set
Fondazione IRCCS Istituto Nazionale per lo studio e la cura dei Tumori, Milano, Not set
AOU dell'Universit~ degli Studi della Campania Luigi Vanvitelli, Napoli, Not set
Veneto Institute of Oncology IOV - I.R.C.C.S., Padova, Not set
Azienda Ospedaliero - Universitaria Pisana, Pisa, Not set
Istituto Clinico Humanitas, Rozzano, Not set
Azienda Sanitaria Universitaria Friuli Centrale - P.O. S. Maria della Misericordia, Udine, Not set
Azienda Ospedaliera Universitaria Integrata Verona, Verona, Not set
Aichi Cancer Center, Nagoya-shi, Aichi
Chiba Cancer Center, Chiba-shi, Chiba
National Cancer Center Hospital East, Kashiwa, Chiba
National Hospital Organization Shikoku Cancer Center, Matsuyama-Shi, Ehime
National Hospital Organization Kyushu Cancer Center, Fukuoka-shi, Fukuoka
Hokkaido University Hospital, Sapporo-Shi, Hokkaidô
Kanazawa University Hospital, Kanazawa-shi, Isikawa
Kagoshima University Hospital, Kagoshima-shi, Kagoshima
Kanagawa Cancer Center, Yokohama-shi, Kanagawa
Kyoto University Hospital, Kyoto City, Kyôto
Mie University Hospital, Tsu-Shi, Mie
Tohoku University Hospital, Sendai-Shi, Miyagi
Niigata University Medical and Dental Hospital, Niigata-shi, Niigata
Osaka Prefectural Hospital Organization Osaka International Cancer Institute, Osaka-shi, Osaka
The University of Tokyo Hospital, Bunkyo-ku, Tokyo
National Cancer Center Hospital, Chuo-Ku, Tokyo
The Cancer Institute Hospital of Japanese Foundation For Cancer Research, Koto-Ku, Tokyo
Kyorin University Hospital, Mitaka-shi, Tokyo
Yamaguchi University Hospital, Ube-Shi, Yamaguchi
Osaka University Hospital, Suita-Shi, Ôsaka
CHA Bundang Medical Center, CHA University, Bundang-Gu, Seongnam-Si, Gyeonggi-do
National Cancer Center, Ilsandong-gu, Goyang-si, Gyeonggi-do
Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do
Pusan National University Hospital, Busan, Not set
Korea University Anam Hospital, Seoul, Not set
Seoul National University Hospital, Seoul, Not set
Severance Hospital, Yonsei University Health System, Seoul, Not set
Hanyang University Seoul Hospital, Seoul, Not set
Asan Medical Center, Seoul, Not set
Samsung Medical Center, Seoul, Not set
Korea University Guro Hospital, Seoul, Not set
Unidade Local de Saude de Almada-Seixal, E.P.E. - Hospital Garcia de Orta, Almada, Not set
Unidade Local de Saude de Coimbra, EPE - Hospitais da Universidade de Coimbra, Coimbra, Not set
Unidade Local de Saúde de São José - Hospital de Santo António dos Capuchos, Lisboa, Not set
Champalimaud Clinical Center, Lisboa, Not set
Instituto Português de Oncologia Do Porto Francisco Gentil, EPE, Porto, Not set
Hospital Oncologico, Puerto Rico Medical Center, Rio Piedras, Not set
Spital Clinic Judetean de Urgenta Bihor, Oradea, Bihor
Centrul De Oncologie "SF. Nectarie" S.R.L., Craiova, Dolj
Institutul Clinic Fundeni, Bucharest, Not set
Centrul de Oncologie Euroclinic SRL, Iasi, Not set
University Clinical Center of Serbia, Clinic for Gastroenterohepatology, Belgrade, Not set
Military Medical Academy, Clinic for Gastroenterology and Hepatology, Belgrade, Not set
Oncology Institute of Vojvodina, Internal Oncology Clinic, Sremska Kamenica, Not set
Complejo Hospitalario Universitario de Santiago -Hospital Clinico Universitario de Santiago, Santiago de Compostela, A Coruna
Vall d'Hebron Institute of Oncology/Hospital Universitari de Vall d'Hebron, Barcelona, Not set
Hospital Universitario Reina Sofia, Cordoba, Not set
Hospital Universitario Fundacion Jimenez Diaz, Madrid, Not set
Hospital Universitario 12 de Octubre, Madrid, Not set
Hospital Universitario La Paz, Madrid, Not set
Hospital Regional Universitario de Malaga, Malaga, Not set
Clinica Universidad de Navarra, Pamplona, Not set
Hospital Universitario Virgen Macarena, Sevilla, Not set
Hospital Universitario y Politecnico La Fe, Valencia, Not set
Hospital Universitario Miguel Servet, Zaragoza, Not set
Onkologiska mottagningen, Sahlgrenska Universitetssjukhuset, Göteborg, Not set
Cancerstudieenheten Huddinge, Karolinska Universitetssjukhuset Huddinge, Huddinge, Not set
Onkologiska mottagningen, Skånes Universitetssjukhus Malmö, Malmö, Not set
Kaohsiung Medical University - Chung-Ho Memorial Hospital, Kaohsiung, Not set
Chang Gung Memorial Hospital Kaohsiung Branch of the Chang Gung Medical Foundation, Kaohsiung, Not set
National Cheng Kung University Hospital, Tainan, Not set
National Taiwan University Cancer Center, Taipei, Not set
Chang Gung Memorial Hospital Linkou Branch of the Chang Gung Medical Foundation, Taoyuan, Not set
Istanbul University Cerrahpasa Medical Faculty Hospital/Clinical Research Center, Istanbul, Fatih
Hacettepe University Cancer Institute, Ankara, Sihhiye
Akdeniz University Medical Faculty Hospital, Antalya, Not set
Trakya University Faculty of Medicine, Edirne, Not set
Mount Vernon Cancer Centre, London, England
NHS Foundation Trust Royal Marsden Hospital, London, England
The Christie NHS Foundation Trust, Manchester, England
Royal Marsden Hospital NHS Foundation Trust, Surrey, England
Western General Hospital, Edinburgh Cancer Centre, Edinburgh, Scotland
Conditions: Biliary Tract Cancer
A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)
Recruiting
The purpose of this study is to compare the efficacy and safety of arlo-cel (BMS-986393) versus standard regimens in adult participants with Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma.
The purpose of this study is to compare the efficacy and safety of arlo-cel (BMS-986393) versus standard regimens in adult participants with Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/19/2025
Locations: Local Institution - 0071, Birmingham, Alabama +123 locations
Local Institution - 0071, Birmingham, Alabama
UCLA Hematology/Oncology - Santa Monica, Los Angeles, California
Local Institution - 0130, Miami, Florida
Winship Cancer Institute, Emory University, Atlanta, Georgia
Local Institution - 0218, Shreveport, Louisiana
Local Institution - 0196, Boston, Massachusetts
Local Institution - 0067, Charlotte, North Carolina
Local Institution - 0216, Winston-Salem, North Carolina
Local Institution - 0193, Cleveland, Ohio
Fox Chase Cancer Center, Philadelphia, Pennsylvania
Local Institution - 0044, Salt Lake City, Utah
Local Institution - 0195, Milwaukee, Wisconsin
Hospital Italiano de Buenos Aires, ABB, Ciudad Autónoma De Buenos Aires
Local Institution - 0214, ABB, Ciudad Autónoma De Buenos Aires
Hospital Aleman, Buenos Aires, Ciudad Autónoma De Buenos Aires
Royal Prince Alfred Hospital, Camperdown, New South Wales
Local Institution - 0190, Liverpool, New South Wales
Local Institution - 0140, Brisbane, Queensland
Royal Adelaide Hospital, Adelaide, South Australia
Monash Health, Clayton, Victoria
Peter MacCallum Cancer Centre, Melbourne, Victoria
Local Institution - 0191, Melbourne, Victoria
Fiona Stanley Hospital, Murdoch, Western Australia
Ordensklinikum Linz GmbH Elisabethinen, Linz, Oberösterreich
Hanusch-Krankenhaus, Vienna, Not set
Local Institution - 0220, Edegem, Antwerpen
Local Institution - 0217, Brussels, Bruxelles-Capitale, Région De
Université Catholique de Louvain-Namur - Centre Hospitalier Universitaire Dinant-Godinne - Site Godinne, Yvoir, Namur
UZ Gent, Gent, Oost-Vlaanderen
Local Institution - 0012, Nova Lima, Minas Gerais
Local Institution - 0103, São Paulo, SAO Paulo
Local Institution - 0013, Sao Paulo, São Paulo
Local Institution - 0031, São Paulo, Not set
Local Institution - 0069, Calgary, Alberta
Vancouver General Hospital, Vancouver, British Columbia
QEII Health Sciences Centre - Victoria General Site, Halifax, Nova Scotia
Local Institution - 0192, Hamilton, Ontario
CIUSSS de l'Est-de-l'Île-de-Montréal, Montreal, Quebec
Fakultní nemocnice Brno Bohunice, Brno, Brno-město
Local Institution - 0093, Hradec Kralove, Hradec Králové
Vseobecna fakultni nemocnice v Praze, Praha 2, Not set
Rigshospitalet, Copenhagen, Hovedstaden
Aarhus Universitetshospital, Skejby, Aarhus, Midtjylland
Local Institution - 0208, Roskilde, Sjælland
Odense Universitetshospital, Odense, Syddanmark
Helsinki University Hospital - Comprehensive Cancer Center (HYKS - Syöpäkeskus), Helsinki, Uusimaa
Hopital Claude Huriez - CHU de Lille, Lille, Nord
Local Institution - 0194, Nantes, Pays-de-la-Loire
Centre Hospitalier Lyon Sud, Pierre-Bénite, Rhône
Henri Mondor Hospital, Creteil, Val-de-Marne
Local Institution - 0210, Paris, Not set
TUM Universitätsklinikum, Technische Universität München, Munich, Bayern
Medizinische Hochschule Hannover, Hannover, Niedersachsen
Local Institution - 0211, Magdeburg, Sachsen-Anhalt
Local Institution - 0204, Chemnitz, Sachsen
Universitätsklinikum Leipzig, Leipzig, Sachsen
Local Institution - 0212, Kiel, Schleswig-Holstein
Local Institution - 0213, Berlin, Not set
Universitaetsklinikum Hamburg-Eppendorf, Hamburg, Not set
Universitaetsklinikum Heidelberg, Heidelberg, Not set
Klinikum Nuernberg Nord, Nuremberg, Not set
Universitaetsklinikum Wuerzburg, Wuerzburg, Not set
University Hospital of Patras, Patras, Achaḯa
Evangelismos General Hospital of Athens, Athens, Attikí
Local Institution - 0115, Chaidari, Attikí
Local Institution - 0125, Budapest, Not set
Sheba Medical Center, Ramat Gan, HaMerkaz
Sourasky Medical Center, Tel Aviv, Tell Abīb
Hadassah Medical Center, Jerusalem, Yerushalayim
Local Institution - 0107, Milan, Lombardia
Istituto Clinico Humanitas, Rozzano, Milano
Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino, Torino, Piemonte
IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico di Sant'Orsola, Bologna, Not set
Local Institution - 0119, Genova, Not set
Local Institution - 0106, Udine, Not set
Nagoya City University Hospital, Nagoya, Aichi
Local Institution - 0105, Kashiwa, Chiba
Hyogo Medical University Hospital, Nishinomiya, Hyogo
Kanazawa University Hospital, Kanazawa, Ishikawa
Kyushu University Hospital, Fukuoka, Not set
Kumamoto University Hospital, Kumamoto, Not set
National Hospital Organization Okayama Medical Center, Okayama, Not set
Osaka Red Cross Hospital, Osaka, Not set
Japanese Red Cross Medical Center, Tokyo, Not set
Yamagata University Hospital, Yamagata, Not set
Local Institution - 0147, Seoul, Seoul-teukbyeolsi [Seoul]
Local Institution - 0146, Seoul, Seoul-teukbyeolsi [Seoul]
Local Institution - 0148, Seoul, Seoul-teukbyeolsi [Seoul]
Local Institution - 0149, Seoul, Seoul-teukbyeolsi [Seoul]
Local Institution - 0176, Nijmegen, Gelderland
Maastricht UMC+, Maastricht, Limburg
Local Institution - 0179, Amsterdam, Noord-Holland
Universitair Medisch Centrum Utrecht, Utrecht, Not set
Oslo Universitetssykehus Ullevål, Oslo, Not set
Centrum Onkologii Ziemi Lubelskiej, Lublin, Lubelskie
Uniwersyteckie Centrum Kliniczne, Gdańsk, Pomorskie
Local Institution - 0084, Katowice, Not set
Local Institution - 0183, Łódź, Łódzkie
Instituto Português de Oncologia do Porto Francisco Gentil, EPE, Porto, Not set
Fundeni Clinical Institute, Bucuresti, București
Institutul Regional de Oncologie, Iași, Not set
Local Institution - 0178, Riyadh, Not set
Local Institution - 0180, Singapore, Central Singapore
Local Institution - 0181, Singapore, Central Singapore
CHUS - Hospital Clinico Universitario, Santiago de Compostela, A Coruña [La Coruña]
Local Institution - 0203, Palma, Balears [Baleares]
Local Institution - 0201, Badalona, Barcelona [Barcelona]
Clinica Universidad de Navarra, Pamplona, Navarra
Local Institution - 0202, Granada, Not set
Hospital Universitario de Salamanca - Complejo Asistencial Universitario de Salamanca, Salamanca, Not set
Local Institution - 0023, Lund, Skåne Län [se-12]
Karolinska Universitetssjukhuset Huddinge, Huddinge, Not set
Inselspital Bern, Bern, Berne
Cantonal Hospital St.Gallen, st.Gallen, Sankt Gallen
Local Institution - 0150, Taipei City, Taipei
Local Institution - 0151, Taichung, Not set
Local Institution - 0152, Taipei, Not set
Local Institution - 0200, Taipei, Not set
Local Institution - 0170, Ankara, Not set
Addenbrooke's Hospital, Cambridge, Cambridgeshire
Local Institution - 0155, London, London, City Of
Local Institution - 0157, Oxford, Oxfordshire
The Christie NHS Foundation Trust, Manchester, Not set
Freeman Hospital, Newcastle upon Tyne, Not set
Conditions: Relapsed or Refractory Multiple Myeloma (RRMM)
A Study to Assess the Concentration of Bimekizumab in Mature Breast Milk From Mothers Receiving Treatment With Bimzelx® (Bimekizumab)
Recruiting
Primary purpose of the study is to assess the concentration of bimekizumab in mature human breast milk.
Primary purpose of the study is to assess the concentration of bimekizumab in mature human breast milk. Read Less
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
08/19/2025
Locations: Up0122 202, Calgary, Not set
Up0122 202, Calgary, Not set
Conditions: Moderate to Severe Plaque Psoriasis, Psoriatic Arthritis, Axial Spondyloarthritis, Hidradenitis Suppurativa
A Study to Compare the Results of FGFR Testing by Either ctDNA Blood Testing or Standard Tumor Tissue Testing
Recruiting
A new drug, erdafitinib, became available for some patients with bladder cancer that has spread to other organs. To qualify, patients must have specific genetic changes in their tumors. Currently, doctors use tumor tissue samples to check for these genetic changes, but these samples might not accurately reflect the current state of the patient's cancer.
In this study, Investigators will test the patient's blood for these genetic changes in addition to the tumor tissue samples. It is thought tha... Read More
A new drug, erdafitinib, became available for some patients with bladder cancer that has spread to other organs. To qualify, patients must have specific genetic changes in their tumors. Currently, doctors use tumor tissue samples to check for these genetic changes, but these samples might not accurately reflect the current state of the patient's cancer.
In this study, Investigators will test the patient's blood for these genetic changes in addition to the tumor tissue samples. It is thought that the blood test will give a more accurate result.
Investigators hope this study will help to find out if more patients can benefit from erdafitinib than the ones identified by tissue testing only. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/19/2025
Locations: Arthur J.E Child Comprehensive Cancer Centre, Calgary, Alberta +6 locations
Arthur J.E Child Comprehensive Cancer Centre, Calgary, Alberta
Cross Cancer Institute, Edmonton, Alberta
BC Cancer Agency, Vancouver, British Columbia
London Health Sciences Centre, London, Ontario
Ottawa Hospital Research Institute, Ottawa, Ontario
Princess Margaret Cancer Centre, Toronto, Ontario
CHU de Québec-Université Laval, Québec City, Quebec
Conditions: Metastatic Bladder Cancer, Metastatic Urothelial Carcinoma
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