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All Clinical Trials in Canada
A listing of 3904 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
1813 - 1824 of 3904
SmartMom: Teaching by Texting to Promote Health Behaviours in Pregnancy
Recruiting
The goal of this randomized clinical trial is to evaluate the effectiveness of SmartMom, a text messaging-based mobile health program for prenatal education. The main questions are to determine if healthy pregnant people receiving SmartMom messages that promote health behaviours in pregnancy versus messages that don't provoke behaviour change have improvement in:
1. knowledge about healthy pregnancy and birth
2. standardized measures of depression, anxiety, and fear of childbirth
3. adoption of... Read More
Gender:
FEMALE
Ages:
15 years and above
Trial Updated:
03/29/2025
Locations: BC Children's Hospital Research Institute, Vancouver, British Columbia
Conditions: Pregnancy
EPI-STORM: Cytokine Storm in Organ Donors
Recruiting
Kidney and liver transplantation are the treatment of choice and are often the last therapeutic option offered to patients with chronic renal and liver failure. More than 70% of kidneys and liver available for transplantation are obtained from donors following neurological death. Unfortunately, compared to living donation, transplant function, graft survival, and recipient survival are consistently inferior with kidneys and liver from neurologically deceased donors. This difference lies with the... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
03/28/2025
Locations: Hôpital Maisonneuve-Rosemont, Montréal, Quebec +3 locations
Conditions: Organ Donation, Liver Transplantation, Kidney Transplantation, Graft Dysfunction
Healthy for my Baby- RCT of a Lifestyle Intervention for Overweight Women in Preconception
Recruiting
The purpose of this study is to determine whether an intervention combining motivational interviewing and follow-up with a mobile phone application will help overweight women and their partners adopt healthy lifestyle habits in the preconception period. This study will also evaluate the impact of the intervention on the weight, waist circumference, and body fat of women and their partners. Women and their partners will be followed through pregnancy to explore the effects of the intervention on t... Read More
Gender:
ALL
Ages:
Between 18 years and 40 years
Trial Updated:
03/28/2025
Locations: Centre de recherche du CHU de Québec Université Laval, Québec, Quebec +1 locations
Conditions: Overweight and Obesity, Pregnancy Complications, Health Behavior, Life Style, Preconception Care
A Non-pharmacological Cough Control Therapy
Recruiting
Coughing affects almost all individuals with ILD leading to physical, psychological and social distress and prevents individuals from performing their activities of daily living, working or socialising in public places. Unfortunately, there are no licensed medications available to treat chronic cough and the few drugs that have been tried resulted in little efficacy and significant side effects. Drug-free cough control interventions have shown promise in reducing the severity and impact of cough... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
03/28/2025
Locations: St. Joseph's Healthcare Hamilton, Hamilton, Ontario +1 locations
AERIAL Trial: Antiplatelet Therapy in Heart Transplantation
Recruiting
Cardiac allograft vasculopathy is a common complication affecting heart transplant patients. This condition causes narrowing of the heart arteries leading to graft dysfunction. The research team is investigating whether early antiplatelet therapy post heart transplant can prevent the development of CAV. This study will determine the feasibility of a large multicenter randomized placebo-controlled trial to answer this question.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/28/2025
Locations: St.Pauls Hospital, Vancouver, British Columbia +2 locations
Conditions: Cardiac Allograft Vasculopathy, Heart Transplant
Hypoxia, Appetite, and Energy Intake in Young Female Adults
Recruiting
The goal of this clinical trial is to investigate the effects of acute passive continuous hypoxemia (simulated high-altitude at rest) on appetite and energy intake in healthy young female adults. The main questions it aims to answer are:
* Does six hours of simulated high-altitude (5000 meters) reduce scores of subjective appetite and energy intake?
* Do changes in appetite and energy intake persist in the hours following the end of hypoxic exposure? Researchers will compare the effects of simu... Read More
Gender:
FEMALE
Ages:
Between 18 years and 30 years
Trial Updated:
03/28/2025
Locations: Behavioural and Metabolic Research Unit, School of Human Kinetics, Faculty of Health Sciences, University of Ottawa, Ottawa, Ontario
Conditions: Hypoxia, Altitude, Appetite, Energy Intake
A Study of DSP-5336 in Relapsed/Refractory AML/ ALL With or Without MLL Rearrangement or NPM1 Mutation
Recruiting
A phase 1/2 dose escalation / dose expansion study of Enzomenib (DSP-5336) in adult patients with acute leukemia.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/28/2025
Locations: Hoag Family Cancer Center, Newport Beach, California +91 locations
Conditions: Leukemia, Myeloid, Acute, Leukemia, Lymphocytic, Acute
MARINER Trial: Multiparametric Cardiac PET for CAV Surveillance After Heart Transplantation
Recruiting
Cardiac allograft vasculopathy (CAV) is a common complication affecting heart transplant patients. This condition causes narrowing of the heart arteries leading to graft dysfunction. Surveillance for CAV is vital; however an ideal approach has not been established. The goal of this study is to assess whether noninvasive positron emission tomography (PET) based surveillance is non-inferior to invasive coronary angiography (ICA) surveillance.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/28/2025
Locations: University of Calgary, Calgary, Alberta +4 locations
Conditions: Cardiac Allograft Vasculopathy
Deep Brain Reorienting in Post-traumatic Stress Disorder
Recruiting
This study will evaluate the efficacy of a therapeutic treatment, Deep Brain Reorienting (DBR), for PTSD (Post-traumatic Stress Disorder). Participants will be randomized to either the DBR treatment, or wait-list condition.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
03/27/2025
Locations: London Health Sciences Centre - University Hospital, London, Ontario
Conditions: PTSD, Post-traumatic Stress Disorder
Weight-Bearing CT and Conventional Periprosthetic Distal Knee Fractures
Recruiting
Total knee arthroplasty (TKA) is a surgical procedure commonly conducted for patients with end-stage knee osteoarthritis, often leading to improved pain relief and function. However, for patients that have suffered an associated periprosthetic fracture, a broken bone that occurs around the implant of a TKA, they may receive sub-optical care due to a lack of a trustworthy assessments for component fixation and fracture healing in the literature. The prevalence of TKA surgeries is increasing annua... Read More
Gender:
ALL
Ages:
Between 50 years and 90 years
Trial Updated:
03/27/2025
Locations: University Hospital - London Health Sciences Centre, London, Ontario
Conditions: Periprosthetic Fracture Around Prosthetic Joint Implant
Influence of Oxygenator Selection on Platelet Function and Rotational Thromboelastometry Following Cardiopulmonary Bypass
Recruiting
Open-heart surgery requires temporarily stopping the heart and lungs and diverting the patient's blood to an outside system that takes over the function of the heart and lungs. This is possible through the use of cardiopulmonary bypass (CPB) which diverts blood, through plastic tubing, to a heart-lung machine which includes an oxygenator. The external oxygenator works as an artificial lung. This allows cardiac surgeons to operate in a field that is free of blood, while the patient's body continu... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/27/2025
Locations: Halifax Infirmary site, Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia
Conditions: Platelet Dysfunction, Cardiopulmonary Bypass
RAPID AFib Decision Aid for Stroke Prevention in Atrial Fibrillation
Recruiting
The goal of this pilot clinical trial is to evaluate the utility of a new electronic patient decision aid for stroke prevention therapy in patients with atrial fibrillation. The main questions it aims to answer are:
Is the patient decision aid acceptable to both patients and physicians? Does the patient decision aid lead to more effective shared decision-making than standard care among patients with atrial fibrillation who are considering stroke prevention therapy? Participants with a recent di... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/27/2025
Locations: Calgary Zone, Alberta Health Services, Calgary, Alberta +1 locations
Conditions: Atrial Fibrillation
1813 - 1824 of 3904
