Tryptophan Requirements During Pregnancy
NCT06519071
Recruiting
Pregnancy is an important period of life where there is an increased need for nutrients including protein and amino acids from food. The current protein and amino acids dietary recommendations were all established using older methods done in adult men. Then protein and amino acids requirements for all stages of pregnancy were calculated without accounting for changing demands in each trimester. Therefore, another more precise method is needed to better understand how much amino acids (in this st... Read More
Gender:
FEMALE
Ages:
Between 20 years and 40 years
Trial Updated:
01/27/2025
Locations: BC Children's Hospital Research Institute, University of British Columbia, Vancouver, British Columbia
Conditions: Pregnancy
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A Study to Evaluate the Pharmacokinetics (PK), Safety and Tolerability of Single- and Multiple-Ascending Doses of MH-001 in Healthy Volunteers
NCT06780254
Recruiting
First-in-Human study to demonstrate the safety and tolerability of single- and multiple-ascending doses of MH-001 in Healthy Volunteers (HVs)
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/27/2025
Locations: Syneos Health clinic, Quebec, Not set
Conditions: Healthy
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Evaluation and Treatment of Adhesive Capsulitis Using Non-invasive Neurostimulation Devices
NCT06795932
Recruiting
The goal of this randomized controlled trial is to compare the integrity of somatosensory processing with transcranial magnetique stimulation (TMS) and corticospinal excitability of the affected shoulder in individuals with adhesive capsulitis versus healthy controls. The secondary objective is to compare the clinical and neurophysiological effects of an intervention using tendon vibration (VIB) to induced kinesthetic illusions. This will involve comparing two groups: one receiving a real inter... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/27/2025
Locations: Lab BioNR - UQAC, Saguenay, Quebec
Conditions: Adhesive Capsulitis of the Shoulder, Frozen Shoulder
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Technology-Enabled Collaborative Care for Young Adults with Type 1 Diabetes and Diabetes Distress: a Feasibility Trial
NCT06804694
Recruiting
The goal of the study is to evaluate the acceptability and feasibility of a co-designed, Technology-Enabled Collaborative Care for Young Adults with Type-1 Diabetes and Diabetes Distress (TECC-T1D3) program. Through this program, the investigators aim to deliver a collaborative care intervention, featuring a health coach and a virtual care team, designed to help participants manage mental health and overall wellbeing.
Gender:
ALL
Ages:
Between 18 years and 29 years
Trial Updated:
01/27/2025
Locations: Centre for Addiction and Mental Health, Toronto, Ontario
Conditions: Type 1 Diabetes (T1D), Diabetes Distress
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Self-hypnosis Training for Chronic Pain Management
NCT06279650
Recruiting
Title: Self-hypnosis training in chronic pain management: A pilot study Our primary objective concerns the effect of hypnosis intervention on change in 24h pain between T0 (pre-intervention) and T4 (3-month follow-up). The secondary objectives concern the effects of the intervention on (i) change in 24h pain between T0 and T5 (6-month follow-up), (ii) changes from T0 in measures of the functional impact of pain, (iii) changes from T0 in anxiety-depression scores and (iv) changes from T0 in quali... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/25/2025
Locations: 5415 Bd de l'Assomption, Montréal, Quebec
Conditions: Hypnosis, Chronic Pain Management
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Evaluating the Efficacy of Platelet-Rich-Plasma (PRP) for Erectile Dysfunction
NCT06264635
Recruiting
There is great interest in restorative therapies (platelet-rich plasma (PRP) injections, shockwave therapy and stem cell therapy) for ED given their non-invasive nature. However, data is still limited and requires further research prior to widespread adoption. Unfortunately, therapies such as PRP injections are being widely used without clinical evidence demonstrating its safety or effectiveness for the treatment of erectile dysfunction. 2-7 To date, there are no treatments that address the unde... Read More
Gender:
MALE
Ages:
Between 30 years and 70 years
Trial Updated:
01/24/2025
Locations: Men's Health Clinic, Winnipeg, Manitoba
Conditions: Erectile Dysfunction
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A Study to Learn About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus
NCT04961567
Recruiting
In this study, researchers will learn more about a study drug called litifilimab (BIIB059) in participants with systemic lupus erythematosus (SLE). The study will focus on participants who have active disease and are already taking standard of care medications. These may include antimalarials, steroids, and immunosuppressants. The main objective of the study is to learn about the effect litifilimab has on lowering the activity of the disease. The main question researchers want to answer is: -... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/23/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama +178 locations
Conditions: Lupus Erythematosus, Systemic
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Caudal Analgesia & Anticoagulated Patient
NCT05946850
Recruiting
Caudal analgesia is an effective intervention for lumbosacral pain. Some chronic pain patients take anticoagulants for vasculopathy treatment. Anticoagulation limits the use of caudal analgesia because of the risk of epidural bleeding. Caudal analgesia may be safe and effective in anticoagulated chronic pain patients. Quantitative analysis of prospective clinical data. Evaluation of caudal analgesia efficacy and safety in anticoagulated chronic pain patients. Analysis of outcome, and complicati... Read More
Gender:
ALL
Ages:
Between 20 years and 99 years
Trial Updated:
01/23/2025
Locations: Salem Anaesthesia Pain Clinic, Surrey, British Columbia
Conditions: Lumbar Pain Syndrome, Anticoagulants and Bleeding Disorders
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Ketamine Enhances Analgesia and Mood in Chronic Pain Patients
NCT05985811
Recruiting
Most chronic pain patients have mood disorders. The mood disorders may improve with better analgesia produced by Ketamine injections. A prospective study of patients undergoing interventional pain therapy using Ketamine injections. Pre-injection and post-injection patient data is collected. Pain is measured using numeric pain rating scale, and change in pain score by 2-points is considered significant. Sleep is measured using Likert sleep scale, and change in sleep score by 2-points is considere... Read More
Gender:
ALL
Ages:
Between 20 years and 99 years
Trial Updated:
01/23/2025
Locations: Salem Anaesthesia Pain Clinic, Surrey, British Columbia
Conditions: Mood Disorder; Opioid, Mood Insomnia
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Reducing Respiratory Symptoms of Pulmonary Irradiation in Interstitial Lung Disease
NCT05986318
Recruiting
In this double-blind phase II randomized controlled trial, patients with lung cancer or ≤2 oligometastatic pulmonary lesions and a concomitant diagnosis of ILD who are planned for radical Radiation Therapy (RT) will be randomized using a 2 x 2 factorial design to oral N-acetylcysteine (NAC) versus placebo, and also to short course corticosteroids versus placebo.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/23/2025
Locations: London Regional Cancer Program, London Health Sciences Centre, London, Ontario +1 locations
Conditions: Lung Cancer, Interstitial Lung Disease
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Pain Clinic Provides Public Health Safety
NCT06076512
Recruiting
Chronic pain is associated with psychological disorders; which may affect a patient's socioeconomic, legal, domestic, and employment situations. This prospective observational study evaluates the impact of pain management on patients' health, social, economic, and employment status. It explores the impact of pain clinic services on patients' mental health, family health, public health, road safety, addiction situation, public safety, injury rehabilitation and employment situation.
Gender:
ALL
Ages:
Between 20 years and 99 years
Trial Updated:
01/23/2025
Locations: Salem Anaesthesia Pain Clinic, Surrey, British Columbia
Conditions: Social Functioning, Addiction, Substance, Safety Issues, Road Injury, Patient Compliance, Chronic Pain
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Chronic Pelvic Pain in Females and Males
NCT06102733
Recruiting
Pelvic pain is under-reported in healthy adults. Many patients with pelvic pain under-estimate the problem. Chronic pelvic pain can be managed properly, if diagnosed promptly. This is a quantitative analysis of prospective clinical data. It evaluates the management of pelvic pain in a cohort population, and analyzes the treatment outcome.
Gender:
ALL
Ages:
Between 20 years and 99 years
Trial Updated:
01/23/2025
Locations: Salem Anaesthesia Pain Clinic, Surrey, British Columbia
Conditions: Pelvic Pain Syndrome, Sacroiliac Disorder, Piriformis Syndrome, Sacrococcygeal Disorder, Inguinal Hernia
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