A Study to Learn About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus
NCT04961567
Recruiting
In this study, researchers will learn more about a study drug called litifilimab (BIIB059) in participants with systemic lupus erythematosus (SLE). The study will focus on participants who have active disease and are already taking standard of care medications. These may include antimalarials, steroids, and immunosuppressants. The main objective of the study is to learn about the effect litifilimab has on lowering the activity of the disease. The main question researchers want to answer is: -... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/23/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama +178 locations
Conditions: Lupus Erythematosus, Systemic
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Magnesium Injection Ensures Steroid Avoidance During Vaccine, Viremia or Immunocompromise
NCT05862454
Recruiting
Steroid injections are used for interventional pain management. However, their side-effect of immunosuppression may increase the risk of infections. Magnesium is an alternative anti-nociceptive injection that may be used instead of steroids. Prospective observational study of patients who received magnesium injection for interventional pain therapy, instead of steroid injection. Post-injection data collection includes numerical rating pain score, and sleep quality score. Pain is measured using... Read More
Gender:
ALL
Ages:
Between 20 years and 99 years
Trial Updated:
01/23/2025
Locations: Salem Anaesthesia Pain Clinic, Surrey, British Columbia
Conditions: Steroid Metabolism Disorder
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Premedication for Claustrophobic Patients for MRI Scan
NCT05876117
Recruiting
Claustrophobia is an irrational fear of restriction and suffocation. It is a specific phobia, according to DSM 5. Claustrophobic patients may fear that restriction of their limbs will hinder their ability to move quickly towards safety. MRI may trigger claustrophobia, because this diagnostic procedure involves a patient laying in a narrow tube. Premedication before MRI scan may occasionally reduce claustrophobia. Prospective observational crossover study of claustrophobic patients who are under... Read More
Gender:
ALL
Ages:
Between 20 years and 99 years
Trial Updated:
01/23/2025
Locations: Salem Anaesthesia Pain Clinic, Surrey, British Columbia
Conditions: Claustrophobia
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Kratom Use Disorder Management Using Clonidine and/or Buprenorphine
NCT05883358
Recruiting
Kratom is used for stimulant, analgesic, anxiolytic, and sedative effects. There is inadequate knowledge about Kratom addiction. Kratom withdrawal may be treated like opioid withdrawal. Prospective observational crossover study of consenting adults who are undergoing Kratom withdrawal management. On alternate weeks, each patient receives treatment using Buprenorphine 5cmg/hr patch; or Clonidine tablet 0.1mg 4hourly; or combined Clonidine tablet 0.1mg 4hourly + Buprenorphine 5cmg/hr patch. Each... Read More
Gender:
ALL
Ages:
Between 20 years and 99 years
Trial Updated:
01/23/2025
Locations: Salem Anaesthesia Pain Clinic, Surrey, British Columbia
Conditions: Withdrawal Syndrome
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COVID Infection in Pediatric Surgical Patient
NCT05898529
Recruiting
Children infected with COVID-19 are mostly asymptomatic. There is a dearth of data on the epidemiology of COVID-19 in the pediatric population. This is a prospective observational clinical study of pediatric surgical patients. COVID-19 rapid antigen testing will be performed on pediatric patients.
Gender:
ALL
Ages:
Between 2 years and 17 years
Trial Updated:
01/23/2025
Locations: Salem Anaesthesia Pain Clinic, Surrey, British Columbia
Conditions: COVID-19
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Pain Clinic Staff Harassed by Patients Pre/Post COVID
NCT05938101
Recruiting
Chronic pain may cause psychological or behavioral problems. Chronic pain patients occasionally harass the pain care providers. The COVID-19 pandemic caused major stress for the general population. Quantitative and qualitative analysis of prospective electronic and clinic diary data. Evaluation of incidents of clinic staff harassment; caused by patients, before and during COVID pandemic. Analysis of causative factors, incident outcome and lessons learned.
Gender:
ALL
Ages:
Between 20 years and 99 years
Trial Updated:
01/23/2025
Locations: Salem Anaesthesia Pain Clinic, Surrey, British Columbia
Conditions: Patient Violence
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Discrimination Harassment of Pain Staff Caused by Patient
NCT05945719
Recruiting
Chronic pain is associated with mental disorders, and some patients have behavioral issues. Some patients may sexually or racially harass pain clinic staff. Healthcare staff do not usually report sexual or racial harassment perpetrated by patients. Quantitative and qualitative analysis of prospective electronic and clinic diary data. Evaluation of incidents of sexual and racial harassment of clinic staff; perpetrated by patients. Analysis of causative factors, incident outcome, system factors a... Read More
Gender:
ALL
Ages:
Between 20 years and 99 years
Trial Updated:
01/23/2025
Locations: Salem Anaesthesia Pain Clinic, Surrey, British Columbia
Conditions: Abuse, Sexual, Abuse, Workplace
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Caudal Analgesia & Anticoagulated Patient
NCT05946850
Recruiting
Caudal analgesia is an effective intervention for lumbosacral pain. Some chronic pain patients take anticoagulants for vasculopathy treatment. Anticoagulation limits the use of caudal analgesia because of the risk of epidural bleeding. Caudal analgesia may be safe and effective in anticoagulated chronic pain patients. Quantitative analysis of prospective clinical data. Evaluation of caudal analgesia efficacy and safety in anticoagulated chronic pain patients. Analysis of outcome, and complicati... Read More
Gender:
ALL
Ages:
Between 20 years and 99 years
Trial Updated:
01/23/2025
Locations: Salem Anaesthesia Pain Clinic, Surrey, British Columbia
Conditions: Lumbar Pain Syndrome, Anticoagulants and Bleeding Disorders
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Ketamine Enhances Analgesia and Mood in Chronic Pain Patients
NCT05985811
Recruiting
Most chronic pain patients have mood disorders. The mood disorders may improve with better analgesia produced by Ketamine injections. A prospective study of patients undergoing interventional pain therapy using Ketamine injections. Pre-injection and post-injection patient data is collected. Pain is measured using numeric pain rating scale, and change in pain score by 2-points is considered significant. Sleep is measured using Likert sleep scale, and change in sleep score by 2-points is considere... Read More
Gender:
ALL
Ages:
Between 20 years and 99 years
Trial Updated:
01/23/2025
Locations: Salem Anaesthesia Pain Clinic, Surrey, British Columbia
Conditions: Mood Disorder; Opioid, Mood Insomnia
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Reducing Respiratory Symptoms of Pulmonary Irradiation in Interstitial Lung Disease
NCT05986318
Recruiting
In this double-blind phase II randomized controlled trial, patients with lung cancer or ≤2 oligometastatic pulmonary lesions and a concomitant diagnosis of ILD who are planned for radical Radiation Therapy (RT) will be randomized using a 2 x 2 factorial design to oral N-acetylcysteine (NAC) versus placebo, and also to short course corticosteroids versus placebo.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/23/2025
Locations: London Regional Cancer Program, London Health Sciences Centre, London, Ontario +1 locations
Conditions: Lung Cancer, Interstitial Lung Disease
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Pain Clinic Provides Public Health Safety
NCT06076512
Recruiting
Chronic pain is associated with psychological disorders; which may affect a patient's socioeconomic, legal, domestic, and employment situations. This prospective observational study evaluates the impact of pain management on patients' health, social, economic, and employment status. It explores the impact of pain clinic services on patients' mental health, family health, public health, road safety, addiction situation, public safety, injury rehabilitation and employment situation.
Gender:
ALL
Ages:
Between 20 years and 99 years
Trial Updated:
01/23/2025
Locations: Salem Anaesthesia Pain Clinic, Surrey, British Columbia
Conditions: Social Functioning, Addiction, Substance, Safety Issues, Road Injury, Patient Compliance, Chronic Pain
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Chronic Pelvic Pain in Females and Males
NCT06102733
Recruiting
Pelvic pain is under-reported in healthy adults. Many patients with pelvic pain under-estimate the problem. Chronic pelvic pain can be managed properly, if diagnosed promptly. This is a quantitative analysis of prospective clinical data. It evaluates the management of pelvic pain in a cohort population, and analyzes the treatment outcome.
Gender:
ALL
Ages:
Between 20 years and 99 years
Trial Updated:
01/23/2025
Locations: Salem Anaesthesia Pain Clinic, Surrey, British Columbia
Conditions: Pelvic Pain Syndrome, Sacroiliac Disorder, Piriformis Syndrome, Sacrococcygeal Disorder, Inguinal Hernia
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