All Clinical Trials in Canada

A listing of 3905 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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Virtual Reality and Field Training to Enhance Community Walking After Stroke

NCT04559373

Recruiting

While stroke survivors discharged from rehabilitation present with some recovery in mobility, their ability to ambulate in the community remains limited. The investigators propose to test a novel, low-cost, intensive and individually tailored intervention that combines virtual reality (VR) and field training to enhance community ambulation and participation in stroke survivors discharged from rehabilitation. The aims are to: (1) Assess feasibility, acceptability, safety and adherence of the int... Read More

Gender:

ALL

Ages:

Between 40 years and 74 years

Trial Updated:

11/20/2024

Locations: Jewish Rehabilitation Hospital, Laval, Quebec +1 locations

Conditions: Stroke

Learn More ›

The PulsePoint Study

NCT04806958

Recruiting

This randomized controlled trial will evaluate whether use of the PulsePoint system increases bystander CPR or defibrillator use compared to standard dispatch procedures in patients who suffer non-traumatic, out-of-hospital cardiac arrest in a public location. Half of all suspected cardiac arrest 9-1-1 calls in a public location will receive PulsePoint alerts (treatment arm). The other half of this eligible patient cohort will receive standard dispatch procedures (control arm).

Gender:

ALL

Ages:

All

Trial Updated:

11/20/2024

Locations: Columbus Division of Fire, Columbus, Ohio +2 locations

Conditions: Out-Of-Hospital Cardiac Arrest, Heart Arrest, Heart Diseases, Cardiovascular Diseases

Learn More ›

Comparison of Pulse Oximetry (SpO2) With Different Oximeters and Arterial Saturation (SaO2): Oxygap2 Study

NCT06102499

Recruiting

The oximeter is used to monitor intensive care patients undergoing oxygen therapy. It indicates pulsed oxygen saturation (SpO2), a reflection of arterial oxygen saturation (SaO2) which enables detection of hypoxemia and hyperoxia, both deleterious state. Current SpO2 recommendations aim to reduce both risk of hypoxemia and hyperoxia. SpO2 is considered the 5th vital sign. Current recommendations for SpO2 targets do not consider the variability of oximeters used in clinical practice. This variab... Read More

Gender:

ALL

Ages:

Between 0 years and 100 years

Trial Updated:

11/20/2024

Locations: CHUM, Montréal, Quebec +2 locations

Conditions: Respiratory Failure, Hypoxemia, Hyperoxemia

Learn More ›

Transcranial Direct Current Stimulation and Yoga for Knee Osteoarthritis

NCT06228573

Recruiting

People with knee arthritis often experience constant pain, and current treatments aren't very effective. This can lead to limited movement and more health problems. Knee arthritis is a big part of healthcare costs in Canada, and its pain is a major reason people see doctors. The pain is linked to complex nervous system changes, making current treatments, like exercise, not very successful. To address this, researchers suggest a new approach combining two things: a brain stimulation technique ca... Read More

Gender:

ALL

Ages:

45 years and above

Trial Updated:

11/20/2024

Locations: McMaster University, Hamilton, Ontario +2 locations

Conditions: Knee Osteoarthritis

Learn More ›

Effect of Artificial Sweetener (AFS) on Glucose Metabolism in Patients with Type 1 Diabetes (T1D)

NCT06315725

Recruiting

The goal of this randomized crossover study is to test the prediction that consuming carbohydrates will affect insulin release differently depending on whether Non-Nutritive Sweeteners (NNSs) are consumed simultaneously. We aim to determine whether the predicted effects are associated with oral or post-oral sweet taste receptor signaling,. Our study will focus on patients diagnosed with type 1 diabetes (T1D) who are using an artificial pancreas (AP) system, as it allows us to monitor glucose and... Read More

Gender:

ALL

Ages:

Between 18 years and 45 years

Trial Updated:

11/20/2024

Locations: Center for Innovative Medicine, The Research Institute of the McGill University Health Centre, Montreal, Quebec

Conditions: Type 1 Diabetes (T1D), Healthy Subjects

Learn More ›

COVID-19 Booster and IIV Schedule in Immunocompromised Hosts

NCT06599658

Recruiting

The goal of this pragmatic embedded open-label, 2 x 2 factorial phase II randomized controlled trial is to evaluate strategies to improve COVID-19 booster and influenza vaccine immunogenicity in people living with immunocompromising conditions (PLIC). The main questions it aims to answer are: 1. Is co-administration of seasonal inactivated influenza vaccine (IIV) with the most up-to-date recommended COVID-19 booster dose non-inferior in inducing a 1-month peak protective humoral response against COVID-19, compared to a strategy of sequential administration of COVID-19 booster dose followed by seasonal IIV given one month later? 2. Is the administration of the most up-to-date recommended COVID-19 booster doses at 3-month intervals superior at maintaining a longer term protective humoral immune response, compared to booster doses administered at 6-month intervals? Researchers will compare (1) COVID-19 and Influenza vaccines administered at Day 0 + COVID-19 Booster at a 3-month interval, (2) COVID-19 vaccine administered at Day 0 and Influenza vaccine administered at Day 28 + COVID-19 Booster at a 3-month interval, (3) COVID-19 and Influenza vaccines administered at Day 0 + COVID-19 Booster at a 6-month interval, and (4) COVID-19 vaccine administered at Day 0 and Influenza vaccine administered at Day 28 + COVID-19 Booster at a 6-month interval to see if median neutralization capacity of patient sera is non-inferior in the co- vs. sequential administration arms at 1-month after the initial COVID-19 booster and superior in the 3-month interval arms vs. the 6-month interval arms at 12 months after the initial COVID-19 booster. These outcomes will also be compared at 2-months for question 1 and 6-months for question 2. People living with immunocompromising conditions who take part in the trial will have blood samples drawn to verify immune response, be monitored for changes in clinical events and therapies, and complete questionnaires to verify adverse effects, quality of life and economic impact. Read Less

Gender:

ALL

Ages:

18 years and above

Trial Updated:

11/20/2024

Locations: Research Institute of McGill University Health Centre, Montréal, Quebec +1 locations

Conditions: COVID 19, Influenza, Rheumatoid Arthritis (RA), Systemic Lupus Erthematosus, Inflammatory Bowel Disease, Solid Organ Transplant Recipients, Immunocompromised Host, People Living With HIV

Learn More ›

Playing Piano to Improve Hand Function Early After Stroke

NCT06621771

Recruiting

The goal of this clinical trial is to study the feasibility of a 6-week piano playing training intervention in a subacute stroke population. More specifically, the investigators aim to (1) implement and test the feasibility of the intervention in the subacute stroke rehabilitation program; and (2) explore the acceptability of the supervised training sessions and home practice sessions. Researchers will also (3) estimate and contrast the effects of the piano training intervention as compared to c... Read More

Gender:

ALL

Ages:

Between 40 years and 74 years

Trial Updated:

11/20/2024

Locations: Jewish Rehabilitation Hospital, Laval, Quebec

Conditions: Stroke

Learn More ›

An Adjuvant Study to Evaluate SMS001 (Paclitaxel) in Non-Small Cell Lung Cancer

NCT06693336

Recruiting

This study evaluates the use of SMS001 in patients with lung cancer. SMS001 is a new form of drug Paclitaxel. Doctors want to decide an appropriate safe dose for SMS001 administration, and to see how well it works in treating lung cancer patients.

Gender:

ALL

Ages:

Between 18 years and 80 years

Trial Updated:

11/20/2024

Locations: Toronto General Hospital, Toronto, Ontario

Conditions: Carcinoma, Non-Small-Cell Lung Cancer (NSCLC)

Learn More ›

Mucopolysaccharidosis I (MPS I) Registry

NCT00144794

Recruiting

The Mucopolysaccharidosis I (MPS I) Registry is an ongoing, observational database that tracks the outcomes of patients with MPS I. The data collected by the MPS I Registry will provide information to better characterize the natural history and progression of MPS I as well as the clinical responses of patients receiving enzyme replacement therapy, such as Aldurazyme (Recombinant Human Alpha-L-Iduronidase), or other treatment modalities. The objectives of the Registry are: * To evaluate the lon... Read More

Gender:

ALL

Ages:

All

Trial Updated:

11/19/2024

Locations: Phoenix Children's Hospital- Site Number : 840003, Phoenix, Arizona +179 locations

Phoenix Children's Hospital- Site Number : 840003, Phoenix, Arizona

Arkansas Childrens Hospital- Site Number : 840109, Little Rock, Arkansas

Southern California Permanente Medical Group- Site Number : 840108, Los Angeles, California

USC Health Sciences Center Dept of Genetics- Site Number : 840082, Los Angeles, California

Children's Hospital Oakland- Site Number : 840029, Oakland, California

Children's Hospital of Orange County- Site Number : 840074, Orange, California

Stanford Unviersity MC Dept of Genetics- Site Number : 840022, Palo Alto, California

UC Davis MIND Institute- Site Number : 840010, Sacramento, California

Loma Linda University Children's Hospital- Site Number : 840117, San Bernardino, California

University of California at San Diego- Site Number : 840007, San Diego, California

University of California at San Francisco- Site Number : 840051, San Francisco, California

Children's Hospital IMD Clinic- Site Number : 840069, Aurora, Colorado

University of Colorado at Denver Genetics Site Number : 840068, Aurora, Colorado

Yale - Site Number : 840047, New Haven, Connecticut

Children's National Medical Center- Site Number : 840067, Washington, District of Columbia

University of Florida Dept of Genetics- Site Number : 840083, Gainesville, Florida

University of Florida Pediatrics Genetics- Site Number : 840121, Jacksonville, Florida

The Atwal Clinic- Site Number : 840112, Jacksonville, Florida

University Of Miami SOM- Site Number : 840006, Miami, Florida

Pediatric Endocrine Associates- Site Number : 840017, Tampa, Florida

Emory University School of Medicine- Human Genetics- Site Number : 840060, Decatur, Georgia

Ann and Robert Lurie Children's Hospital- Site Number : 840011, Chicago, Illinois

Rush University Medical Center Genetics- Site Number : 840079, Chicago, Illinois

Indianapolis University School of Medicine- Site Number : 840027, Indianapolis, Indiana

University of Iowa- Site Number : 840032, Iowa City, Iowa

University of Louisville- Genetics- Site Number : 840030, Louisville, Kentucky

Ochsner Medical Center - Site Number : 840120, New Orleans, Louisiana

John Hopkins- Site Number : 840044, Baltimore, Maryland

Massachusetts General Hospital-Genetics- Site Number : 840062, Boston, Massachusetts

Boston Children's Hospital- Site Number : 840093, Boston, Massachusetts

Baystate Health- Site Number : 840002, Springfield, Massachusetts

University of Michigan Pediatrics- Site Number : 840107, Ann Arbor, Michigan

Children's Hospital of Michigan- Site Number : 840066, Detroit, Michigan

Children's Health Care- Site Number : 840114, Minneapolis, Minnesota

University of Minnesota Medical Center Pediatrics- Site Number : 840076, Minneapolis, Minnesota

Washington University of St. Louis- Site Number : 840100, Saint Louis, Missouri

University of Nebraska Medical Center- Pediatrics- Site Number : 840084, Omaha, Nebraska

Children's Specialty Center of Nevada- Site Number : 840008, Las Vegas, Nevada

Joseph M. Sanzari Children's Hospital- Site Number : 840101, Hackensack, New Jersey

Atlantic Health System- Site Number : 840099, Morristown, New Jersey

St. Peter's University Hospital- Site Number : 840016, New Brunswick, New Jersey

St. Joseph's Children's Hospital- Site Number : 840057, Paterson, New Jersey

Northwell Health- Site Number : 840102, Manhasset, New York

New York University School Of Medicine- Site Number : 840040, New York, New York

Metropolitan Hospital Center- Site Number : 840110, New York, New York

University of Rochester Medical Center SOM- Site Number : 840105, Rochester, New York

State University of New York- Site Number : 840052, Syracuse, New York

Duke University Medical Center Genetics Dept- Site Number : 840037, Durham, North Carolina

Cincinnati Children's Hospital-Genetics- Site Number : 840041, Cincinnati, Ohio

UHCMC- Site Number : 840119, Cleveland, Ohio

Nationwide Children's Hospital- Site Number : 840091, Columbus, Ohio

LSD Data Registry Site LLC- Site Number : 840094, Dublin, Ohio

Oregon Health and Science University- Site Number : 840080, Portland, Oregon

Children's Hospital of Philadelphia HUP Medical Genetics- Site Number : 840089, Philadelphia, Pennsylvania

Children's Hospital of Philadelphia- Site Number : 840034, Philadelphia, Pennsylvania

University of Pittsburgh- Site Number : 840023, Pittsburgh, Pennsylvania

Rhode Island Hospital Genetics- Site Number : 840053, Providence, Rhode Island

Greenwood Genetcs- Site Number : 840055, Greenville, South Carolina

Baylor Research Center- Site Number : 840058, Dallas, Texas

University of Utah Health Hospital- Site Number : 840092, Salt Lake City, Utah

University of Virginia School of Medicine-Pediatrics- Site Number : 840078, Charlottesville, Virginia

Children's Hospital of the Kings Daughters- Site Number : 840072, Norfolk, Virginia

Seattle Children's Hospital- Site Number : 840028, Seattle, Washington

University Of Washington Medical Center- Site Number : 840059, Seattle, Washington

Multicare Health System ¿ Mary Bridge Childrens Hospital- Site Number : 840115, Tacoma, Washington

Children's Hospital of Wisconsin-Pediatrics- Site Number : 840054, Milwaukee, Wisconsin

Investigational Site Number : 153032, Ciudad Autónoma de Buenos Aires, Buenos Aires

Investigational Site Number : 153130, Buenos Aires, Not set

Investigational Site Number : 151069, Westmead, New South Wales

Investigational Site Number : 152096, Brisbane, Queensland

Investigational Site Number : 150944, Brussels, Not set

Investigational Site Number : 150517, Brussels, Not set

Investigational Site Number : 151668, Leuven, Not set

Investigational Site Number : 154008, Roeselare, Not set

Centro de Pesquisa Clínica Prédio 21, 2o andar Hospital de Clínicas de Porto Alegre- Site Number : 076001, Porto Alegre, Rio Grande Do Sul

Hospital e Maternidade Celso Pierro - PUC-Campinas- Site Number : 076007, Campinas, São Paulo

Instituto Fernandes Figueira - FIOCRUZ- Site Number : 076004, Rio de Janeiro, Not set

Instituto de Genética e Erros Inatos do Metabolismo - IGEIM- Site Number : 076002, São Paulo, Not set

Investigational Site Number : 124014, Calgary, Alberta

Investigational Site Number : 124002, Edmonton, Alberta

Investigational Site Number : 124011, Vancouver, British Columbia

Investigational Site Number : 124019, Winnipeg, Manitoba

Investigational Site Number : 124022, Moncton, New Brunswick

Investigational Site Number : 124021, London, Ontario

Investigational Site Number : 124006, Toronto, Ontario

Investigational Site Number : 124018, Montreal, Quebec

Investigational Site Number : 124001, Sherbrooke, Quebec

Investigational Site Number : 152003, Los Angeles, Not set

Investigational Site Number : 152001, Talcahuano, Not set

Investigational Site Number : 170001, Bogotá, Not set

Investigational Site Number : 1910001, Zagreb, Not set

Investigational Site Number : 150659, Praha 2, Not set

Investigational Site Number : 151229, København Ø, Not set

Investigational Site Number : 818002, Cairo, Not set

Investigational Site Number : 818001, Cairo, Not set

Investigational Site Number : 250004, Bordeaux, Not set

Investigational Site Number : 250001, BRON Cedex, Not set

Investigational Site Number : 250002, Marseille Cedex 05, Not set

Investigational Site Number : 250005, Paris Cedex 12, Not set

Investigational Site Number : 250003, Paris, Not set

Investigational Site Number : 250006, Vandœuvre-lès-nancy, Not set

Investigational Site Number : 151368, Hamburg, Not set

Investigational Site Number : 150031, Mainz, Not set

Investigational Site Number : 344001, Kowloon, Not set

Investigational Site Number : 3480005, Pécs, Not set

Investigational Site Number : 356003, Ahmedabad, Not set

Investigational Site Number : 356001, Kolkata, Not set

Investigational Site Number : 3560004, Secunderabad, Not set

Investigational Site Number : 356002, Vellore, Not set

Investigational Site Number : 360001, Jakarta, Not set

Investigational Site Number : 154161, Dublin, Not set

Investigational Site Number : 380002, Ancona, Not set

Investigational Site Number : 380004, Cusano Milanino, Not set

Investigational Site Number : 380009, Firenze, Not set

Investigational Site Number : 380003, Genova, Not set

Investigational Site Number : 380007, Milano, Not set

Investigational Site Number : 380005, Napoli, Not set

Investigational Site Number : 380008, Padova, Not set

Investigational Site Number : 380006, Roma, Not set

Investigational Site Number : 380001, Udine, Not set

Investigational Site Number : 392102, Nangoku-shi, Kochi

Investigational Site Number : 392101, Tokyo, Not set

Investigational Site Number : 151149, Seoul, Gyeonggi-do

Investigational Site Number : 154286, Changwon-si, Gyeongsangnam-do

Investigational Site Number : 153178, Yangsan-si, Gyeongsangnam-do

Investigational Site Number : 154148, Yangsan, Gyeongsangnam-do

Investigational Site Number : 153191, Daejeon, Not set

Investigational Site Number : 153225, Jeonnam, Not set

Investigational Site Number : 153180, Seoul, Not set

Investigational Site Number : 153196, Seoul, Not set

Investigational Site Number : 153192, Seoul, Not set

Investigational Site Number : 153212, Seoul, Not set

Investigational Site Number : 153222, Seoul, Not set

Investigational Site Number : 154225, Kuwait, Not set

Investigational Site Number : 4220004, Beirut, Not set

Investigational Site Number : 458001, Jalan Pahang, Not set

Investigational Site Number : 458002, Kuala Lumpur, Not set

Investigational Site Number : 151171, Amsterdam, Not set

Investigational Site Number : 152029, Rotterdam, Not set

Investigational Site Number : 154264, Lahore, Not set

Investigational Site Number : 154266, Lahore, Not set

Investigational Site Number : 608001, Manila, Not set

Investigational Site Number : 150575, Warszawa, Not set

Investigational Site Number : 6200002, Coimbra, Not set

Investigational Site Number : 154177, Cluj Napoca, Not set

Investigational Site Number : 643001, Moscow, Not set

Investigational Site Number : 643002, Moscow, Not set

Investigational Site Number : 682004, Makkah, Not set

Investigational Site Number : 682001, Qatif, Not set

Investigational Site Number : 702001, Singapore, Not set

Investigational Site Number : 703001, Bratislava, Not set

Investigational Site Number : 7520001, Stockholm, Not set

Investigational Site Number : 154093, Chiayi, Not set

Investigational Site Number : 152152, Hualien, Not set

Investigational Site Number : 152246, Kaohsiung City, Not set

Investigational Site Number : 152244, Kaohsiung, Not set

Investigational Site Number : 151534, New Taipei City, Not set

Investigational Site Number : 151500, Putz City, Chia-yi, Not set

Investigational Site Number : 151181, Taichung, Not set

Investigational Site Number : 151179, Taichung, Not set

Investigational Site Number : 153248, Tainan City, Not set

Investigational Site Number : 152153, Tainan City, Not set

Investigational Site Number : 151182, Taipei City, Not set

Investigational Site Number : 152321, Taipei, Not set

Investigational Site Number : 153158, Taoyuan City, Not set

Investigational Site Number : 764002, Bangkok, Not set

Investigational Site Number : 764003, Bangkok, Not set

Investigational Site Number : 764004, Bangkok, Not set

Investigational Site Number : 764001, Bangkok, Not set

Investigational Site Number : 764005, Khon Kaen, Not set

Investigational Site Number : 152287, Birmingham, Not set

Investigational Site Number : 154240, Birmingham, Not set

Investigational Site Number : 152156, Glasgow, Not set

Investigational Site Number : 151646, London, Not set

Investigational Site Number : 151123, London, Not set

Investigational Site Number : 150303, London, Not set

Investigational Site Number : 150455, Manchester, Not set

Investigational Site Number : 152361, Salford, Not set

Investigational Site Number : 154212, Hanoi, Not set

Investigational Site Number : 704002, Ho Chi Minh City, Not set

Conditions: Mucopolysaccharidosis I (MPS I)

Learn More ›

Fecal Microbiota Transplantation for Pouchitis

NCT03545386

Recruiting

This is a randomized double-blind placebo controlled trial involving a single centre (McMaster University) recruiting patients from Hamilton, ON and the surrounding regions, to evaluate whether fecal microbiota transplantation once weekly for six weeks increases the remission rate compared to placebo in patients with active pouchitis.

Gender:

ALL

Ages:

Between 18 years and 99 years

Trial Updated:

11/19/2024

Locations: McMaster University, Hamilton, Ontario

Conditions: Pouchitis

Learn More ›

A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

NCT04065399

Recruiting

Phase 1 dose escalation will determine the maximum tolerated dose (MTD) and recommended Phase 2 dose (RP2D) of revumenib in participants with acute leukemia. In Phase 2, participants will be enrolled in 3 indication-specific expansion cohorts to determine the efficacy, short- and long-term safety, and tolerability of revumenib.

Gender:

ALL

Ages:

30 days and above

Trial Updated:

11/19/2024

Locations: City of Hope Comprehensive Cancer Center, Duarte, California +56 locations

City of Hope Comprehensive Cancer Center, Duarte, California

University Of California Care Medical Group - Norris Comprehensive Cancer Center And Hospital, Los Angeles, California

Stanford Cancer Institute, Palo Alto, California

University of Colorado, Aurora, Colorado

Florida Cancer Specialists and Research Institute, Sarasota, Florida

Moffitt Cancer Center, Tampa, Florida

Emory Winship Cancer Institute, Atlanta, Georgia

Children's Healthcare of Atlanta, Atlanta, Georgia

The University of Chicago Medical Center, Chicago, Illinois

University of Iowa hospital, Iowa City, Iowa

Dana Farber Cancer Institute, Boston, Massachusetts

Washington University in St. Louis School of Medicine, Saint Louis, Missouri

Hackensack University Medical Center, Hackensack, New Jersey

Memorial Sloan Kettering Cancer Center, New York, New York

Montefiore Medical Center, New York, New York

Duke University Medical Center, Durham, North Carolina

University of Cincinnati, Cincinnati, Ohio

Ohio State University, Columbus, Ohio

Oregon Health & Science University, Portland, Oregon

University of Pennsylvania, Philadelphia, Pennsylvania

The University of Texas MD Anderson Cancer Center, Houston, Texas

Huntsman Cancer Institute at the University of Utah, Salt Lake City, Utah

Peter MacCallum Cancer Centre (PMCC), Melbourne, Victoria

Royal Melbourne Hospital (RMH), Parkville, Victoria

Alfred Hospital, Melbourne, Not set

Sir Charles Gairdner Hospital, Nedlands, Not set

Royal North Shore Hospital, Saint Leonards, Not set

University Health Network, Toronto, Not set

The Hospital for Sick Children, Toronto, Not set

Hospital Saint-Louis - APHP, Paris, Not set

Centre Hospitalier Universitaire (CHU) de Bordeaux, Pessac, Not set

Centre Hospitalier Lyon Sud, Pierre-Benite, Not set

Institut Gustave Roussy-Gustave Roussy Cancer Center -DITEP, Villejuif, Not set

University Hospital Of Ulm, Universitatsklinikum Ulm, Ulm, Baden-Württemberg

Universitaetsklinikum Essen (AoR), Essen, Not set

Universitaetsmedizin Greifswald, Greifswald, Not set

Universitaetsmedizin Der Johannes, Gutenberg, Not set

Universitaetsklinikum Hamburg-Eppendorf, Hamburg, Not set

University of Leipzig, Leipzig, Not set

Klinikum Nuernberg Nord, Nürnberg, Not set

Rambam Health Care Campus (RHCC, Haifa, Not set

Shaare Zedek Medical Center, Jerusalem, Not set

Hadassah Medical Center- Ein Kerem, Jerusalem, Not set

Galilee Medical Center, Nahariya, Not set

Rabin Medical Center, Petach Tikva, Not set

Sheba Medical Center, Ramat Gan, Not set

IRCCS Azienda Ospedaliero Universitaria di Bologna, Bologna, Not set

Istituto Romagnolo Per Lo Studio dei tumori Dino Amadori, Meldola, Not set

IRCCS-Istituto Europeo di Oncologia, Milan, Not set

Universita Cattolica Fondazione Policlinico Agostino Gemelli, Roma, Not set

S Bortolo Hospital AULSS 8 Berica, Vicenza, Not set

Vilnius University Hospital Santaros Klinikos, Vilnius, Not set

Princess Maxima Center for Pediatric Oncology, Utrecht, Not set

Hospital Centro Comprensivo de Cancer UPR, San Juan, Not set

Institut Catala d'Oncologia (ICO) - Hospital Duran i Reynals, Hospitalet De Llobregat, Not set

Hospital Universitario Virgen del Rocio, Seville, Not set

Hospital Universitari i Politecnic La Fe de Valencia, Valencia, Not set

Conditions: Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Mixed Lineage Acute Leukemia, Mixed Phenotype Acute Leukemia, Acute Leukemia of Ambiguous Lineage

Learn More ›

Study to Evaluate the Efficacy, Immunogenicity, and Safety of RSVpreF in Adults.

NCT05035212

Recruiting

Efficacy Study: This randomized, double-blinded, placebo-controlled Phase 3 study is designed to assess the safety, immunogenicity, and efficacy of a single dose of RSVpreF in the prevention of LRTI-RSV in adults: * At a dose of 120µg. * In adults 60 years of age and older. * The duration of the study for each participant will be up to approximately 24 months. * The study will be conducted in the United States, Canada, Netherlands, Finland, Argentina, Japan and South Africa. Substudy A: This study is an extension of the efficacy study and was designed to evaluate the safety and immunogenicity of a second dose of RSVpreF when administered after a dosing interval of approximately 2 years: * At a dose of 120µg (as studied in the Phase 3 Efficacy Study) * Blood samples will be collected for antibody testing. * The duration of the study for each participant will be up to approximately 18 months. * The study will be conducted in the United States and Argentina. Substudy B: This study was designed to evaluate the safety and immunogenicity of a second dose of RSVpreF when administered after a dosing interval of approximately 1 year: * At a dose of 120µg (as studied in the Phase 3 Efficacy Study) * Blood samples will be collected for antibody testing. * The duration of the study for each participant will be up to approximately 18 months. * The study will be conducted in Argentina. Substudy C: This study was designed to evaluate the safety and immunogenicity of a second dose of RSVpreF when administered after a dosing interval of either 3 or 4 years: * At a dose of 120µg (as studied in the Phase 3 Efficacy Study) * Participants will receive either placebo or a second dose of RSVpreF approximately 3 or 4 years after receiving the initial dose of RSVpreF in the main efficacy study. * Blood samples will be collected for antibody testing. * The duration of the study for each participant will be up to approximately 18 months. * The study will be conducted in the United States and Canada. Read Less

Gender:

ALL

Ages:

60 years and above

Trial Updated:

11/19/2024

Locations: St. Vincent's Birmingham (Pharmacy), Birmingham, Alabama +327 locations

St. Vincent's Birmingham (Pharmacy), Birmingham, Alabama

St. Vincent's Birmingham, Birmingham, Alabama

Medical Affiliated Research Center, Huntsville, Alabama

Lenzmeier Family Medicine/CCT Research, Glendale, Arizona

Phoenix Clinical LLC, Phoenix, Arizona

HOPE Research Institute, Phoenix, Arizona

The Pain Center of Arizona, Phoenix, Arizona

HOPE Research Institute, Phoenix, Arizona

Cognitive Clinical Trials, LLC, Phoenix, Arizona

Headlands Research - Scottsdale, Scottsdale, Arizona

Alliance for Multispecialty Research, LLC, Tempe, Arizona

HOPE Research Institute, Tempe, Arizona

Noble Clinical Research, Tucson, Arizona

The Institute for Liver Health dba Arizona Clinical Trials, Tucson, Arizona

Hope Clinical Research, Canoga Park, California

eStudySite, Chula Vista, California

Benchmark Research, Colton, California

West Coast Research, Dublin, California

Marvel Clinical Research 002, LLC, Huntington Beach, California

Marvel Clinical Research, Huntington Beach, California

Chemidox Clinical Trials, Lancaster, California

Ark Clinical Research, Long Beach, California

Downtown L.A. Research Center, Inc., Los Angeles, California

Velocity Clinical Research, North Hollywood, North Hollywood, California

Clinica mi Salud by Focil Med, Oxnard, California

Fomat Medical Research, Oxnard, California

De Silva Medical Inc, Palmdale, California

Empire Clinical Research, Pomona, California

Paradigm Clinical Research Center, Redding, California

Artemis Institute for Clinical Research, Riverside, California

Benchmark Research, Sacramento, California

Artemis Institute for Clinical Research, San Diego, California

California Research Foundation, San Diego, California

Diablo Clinical Research, Inc., Walnut Creek, California

Lynn Institute of Denver, Aurora, Colorado

Tekton Research LLC, Longmont, Colorado

Tekton Research, Inc., Longmont, Colorado

Clinical Research Consulting, Milford, Connecticut

Stamford Therapeutics Consortium, Stamford, Connecticut

JEM Research Institute, Atlantis, Florida

IDEAL Clinical Research, Aventura, Florida

Innovative Research of West Florida, Clearwater, Florida

Invictus Clinical Research Group, LLC, Coconut Creek, Florida

Nature Coast Clinical Research, Crystal River, Florida

Universal Axon Clinical Research, LLC (Administrative), Doral, Florida

Indago Research & Health Center, Inc, Hialeah, Florida

Doral Medical Research, LLC, Hialeah, Florida

Wr-Msra.Llc, Lake City, Florida

Global Health Research Center, Inc., Miami Lakes, Florida

Optimus U Corporation, Miami, Florida

Advance Medical Research Center, Miami, Florida

Optimus U Corporation, Miami, Florida

Next Phase Research Alliance, Miami, Florida

New Horizon Research Center, Miami, Florida

De La Cruz Research Center, LLC, Miami, Florida

De La Cruz Research, LLC, Miami, Florida

Clinical Site Partners LLC, dba Flourish Research, Miami, Florida

Clinical Site Partners, Inc dba CSP Miami, Miami, Florida

Headlands Research Orlando, Orlando, Florida

Pines Care Research Center, LLC, Pembroke Pines, Florida

IDEAL Clinical Research, Pembroke Pines, Florida

DBC Research USA, Pembroke Pines, Florida

Headlands Research Sarasota, Sarasota, Florida

Precision Clinical Research, Sunrise, Florida

Clinical Site Partners, Inc, Winter Park, Florida

Conquest Research, LLC, Winter Park, Florida

Conquest Research, Winter Park, Florida

Javara - Privia Medical Group Georgia - Albany, Albany, Georgia

Coastal Heritage Clinical Research, Hinesville, Georgia

Javara - Privia Medical Group Georgia - Savannah, Savannah, Georgia

Javara Inc., Savannah, Georgia

Privia Medical Group Georgia, LLC, Savannah, Georgia

Velocity Clinical Research, Savannah, Savannah, Georgia

Clinical Research Atlanta, Stockbridge, Georgia

Javara Inc., Thomasville, Georgia

Privia Medical Group Georgia, LLC, Thomasville, Georgia

Snake River Research, PLLC, Idaho Falls, Idaho

Solaris Clinical Research, Meridian, Idaho

Great Lakes Clinical Trials, LLC dba Flourish Research, Chicago, Illinois

Great Lakes Clinical Trials, Chicago, Illinois

DM Clinical Research, Melrose Park, Illinois

Affinity Health Corp, Oak Brook, Illinois

Accellacare - DuPage, Oak Lawn, Illinois

Acellacare - DuPage, Oak Lawn, Illinois

DM Clinical Research, River Forest, Illinois

MOC Research, Mishawaka, Indiana

Velocity Clinical Research Valparaiso, Valparaiso, Indiana

University of Iowa Health Care, Iowa City, Iowa

University of Iowa, Iowa City, Iowa

Meridian Clinical Research, LLC, Sioux City, Iowa

Velocity Clinical Research, Sioux City, Sioux City, Iowa

Alliance for Multispecialty Research, LLC, Lexington, Kentucky

Ochsner Clinic Foundation, Kenner, Louisiana

Ochsner Medical Center - Kenner, Kenner, Louisiana

Velocity Clinical Research, Metairie, Metairie, Louisiana

Ochsner Clinic Foundation, New Orleans, Louisiana

Meridian Clinical Research, LLC, Rockville, Maryland

Velocity Clinical Research, Rockville, Rockville, Maryland

Velocity Clinical Research, Rockville, Maryland

ActivMed Practices & Research, LLC, Beverly, Massachusetts

ActivMed Practices & Research, LLC, Methuen, Massachusetts

University of Massachusetts Chan Medical School, Worcester, Massachusetts

Michigan Center of Medical Research (MICHMER), Farmington Hills, Michigan

Ascension St. John Hospital Vaccine Research Unit, Grosse Pointe Woods, Michigan

Oakland Medical Research, Troy, Michigan

Arcturus Healthcare , PLC, Troy Internal Medicine Research Division, Troy, Michigan

Saint Louis University, Saint Louis, Missouri

Sundance Clinical Research, Saint Louis, Missouri

Skyline Medical Center, PC/CCT Research, Elkhorn, Nebraska

Quality Clinical Research, Omaha, Nebraska

Wr-Crcn, Llc., Las Vegas, Nevada

Alliance for Multispecialty Research, LLC, Las Vegas, Nevada

Las Vegas Clinical Trials, North Las Vegas, Nevada

ActivMed Practices and Research, LLC., Portsmouth, New Hampshire

IMA Clinical Research, Raritan, New Jersey

South Jersey Infectious Disease, Somers Point, New Jersey

IMA Clinical Research Warren, Warren, New Jersey

Meridian Clinical Research, LLC, Binghamton, New York

CHEAR Center LLC, Bronx, New York

Drug Trials America, Hartsdale, New York

Corning Center for Clinical Research, Horseheads, New York

Rochester Clinical Research, Inc., Rochester, New York

Rochester Clinical Research, LLC, Rochester, New York

University of Rochester Medical Center, Rochester, New York

Velocity Clinical Research, Vestal, Vestal, New York

Atrium Health - Strive Vaccine Research Clinic, Charlotte, North Carolina

Accellacare - Charlotte, Charlotte, North Carolina

Javara Inc., Charlotte, North Carolina

Tryon Medical Partners, PLLC, Charlotte, North Carolina

Accellacare - Charlotte, Charlotte, North Carolina

Sensenbrenner Primary Care Research Office, Charlotte, North Carolina

Accellacare - Wilmington - 1917 Tradd Court, Wilmington, North Carolina

Accellacare - Wilmington, Wilmington, North Carolina

Wake Forest University Health Sciences, Winston-Salem, North Carolina

Meridian Clinical Research, LLC, Cincinnati, Ohio

Meridian Clinical Research, Cincinnati, Ohio

Velocity Clinical Research, Mt. Auburn, Cincinnati, Ohio

Velocity Clinical Research - Cincinnati, Cincinnati, Ohio

Meridian Clinical Research, LLC, Cincinnati, Ohio

Meridian Clinical Research, Cincinnati, Ohio

Velocity Clinical Research, Springdale, Cincinnati, Ohio

Centricity Research Columbus Ohio Multispecialty, Columbus, Ohio

Tekton Research, Inc, Edmond, Oklahoma

Tekton Research, LLC., Edmond, Oklahoma

Tekton Research, Inc, Yukon, Oklahoma

The Corvallis Clinic, PC, Corvallis, Oregon

Velocity Clinical Research, Grants Pass, Grants Pass, Oregon

Velocity Clinical Research, Medford, Medford, Oregon

Summit Headlands, LLC, Portland, Oregon

Kaiser Permanente Northwest-Center for Health Research, Portland, Oregon

Capital Area Research, LLC, Camp Hill, Pennsylvania

Central Erie Primary Care, Erie, Pennsylvania

West Shore Family Practice, P. C., Mechanicsburg, Pennsylvania

University of Pennsylvania, Philadelphia, Pennsylvania

Penn Prevention Unit, Philadelphia, Pennsylvania

Velocity Clinical Research, Providence, East Greenwich, Rhode Island

Alliance for Multispecialty Research, LLC, Knoxville, Tennessee

Accellacare US Inc., d/b/a Accellacare of Knoxville, Knoxville, Tennessee

Clinical Research Associates, Inc., Nashville, Tennessee

Benchmark Research, Austin, Texas

Innovo Research - Austin Regional Clinic, Austin, Texas

Tekton Research, LLC., Austin, Texas

Tekton Research, Inc., Beaumont, Texas

Tekton Research, LLC., Beaumont, Texas

Javara Inc., Conroe, Texas

Privia Medical Group Gulf Coast, PLLC, Conroe, Texas

North Texas Infectious Diseases Consultants, P.A, Dallas, Texas

Benchmark Research, Fort Worth, Texas

Texas Health Family Care, Fort Worth, Texas

Benchmark Research, Fort Worth, Texas

Allure Health at Mt. Olympus Medical Research, Friendswood, Texas

Hany H. Ahmed, MD, Houston, Texas

Helios Clinical Research - HOU, Houston, Texas

HG Pediatrics, Houston, Texas

Trio Clinical Trials, LLC, Houston, Texas

Van Tran Family Practice, Houston, Texas

Ventavia Research Group, LLC, Houston, Texas

Centex Studies, Houston, Texas

DM Clinical Research - Cy Fair, Houston, Texas

DM Clinical Research ? CyFair, Houston, Texas

DM Clinical Research - Bellaire, Houston, Texas

Texas Center for Drug Development, Inc., Houston, Texas

Centex Studies, Houston, Texas

DM Clinical Research - Humble, Humble, Texas

DM Clinical Research - MDC, Humble, Texas

Milton Haber, M.D., Laredo, Texas

Milton Haber, MD, Laredo, Texas

SMS Clinical Research, Mesquite, Texas

Sun Research Institute, San Antonio, Texas

Clinical Trials of Texas, LLC dba Flourish Research, San Antonio, Texas

Clinical Trials of Texas, LLC, San Antonio, Texas

Dynamed Clinical Research, LP d/b/a DM Clinical Research, Sugar Land, Texas

Javara Inc., Sugar Land, Texas

Privia Medical Group Gulf Coast, PLLC, Sugar Land, Texas

Mt Olympus Medical Research, Sugar Land, Texas

DM Clinical Research, Martin Diagnostic Clinic, Tomball, Texas

Martin Diagnostic Clinic, Tomball, Texas

J. Lewis Research Inc. / Foothill Family Clinic Draper, Draper, Utah

J. Lewis Research, Inc. / Foothill Family Clinic Draper, Draper, Utah

Tanner Clinic, Layton, Utah

J. Lewis Research, Inc. / Jordan River Family Medicine, South Jordan, Utah

Velocity Clinical Research, Salt Lake City, West Jordan, Utah

Centricity Research Suffolk Primary Care, Suffolk, Virginia

Suffolk Multispecialty Research, Suffolk, Virginia

Virginia Gastroenterology Clinical Research, Suffolk, Virginia

Northwest Clinical Research Center, Bellevue, Washington

Sound Medical Research, Port Orchard, Washington

MultiCare Institute for Research & Innovation, Tacoma, Washington

MultiCare Medical Group, Tacoma, Washington

Central Washington Health Services Association d/b/a Confluence Health, Wenatchee, Washington

Research Building, Wenatchee, Washington

Wenatchee Valley Hospital, Wenatchee, Washington

Allegiance Research Specialists, LLC, Wauwatosa, Wisconsin

Hospital Militar Central Cirujano Mayor Dr. Cosme Argerich, Caba, Buenos Aires

Fundación Respirar, Caba, Buenos Aires

Clinica Privada Instituto Medico Platense S.A., La Plata, Buenos Aires

Instituto De Investigaciones Clínicas Mar Del Plata, Mar del Plata, Buenos Aires

Clinica Mayo de Urgencias Medicas Cruz Blanca S.R.L, San Miguel de Tucuman, Tucuman

Hospital de Clinicas Presidente Nicolas Avellaneda, San Miguel de Tucuman, Tucuman

Clinica Privada del Sol S.A., Cordoba, Not set

IMAC - Instituto Medico de Alta Complejidad, Salta, Not set

Kaye Edmonton Clinic, Edmonton, Alberta

Stollery Children's Hospital, Edmonton, Alberta

University Of Alberta Hospital, Edmonton, Alberta

Aggarwal and Associates Limited, Brampton, Ontario

Dawson Clinical Research Inc., Guelph, Ontario

Dawson Clinical Research Inc, Guelph, Ontario

Premier Clinical Trial Network, Hamilton, Ontario

Hamilton Medical Research Group, Hamilton, Ontario

Centricity Research Toronto LMC Multispecialty, Toronto, Ontario

LMC Clinical Research Inc. (Clinical Pharmacology Unit), Toronto, Ontario

Dr. Anil K. Gupta Medicine Professional Corporation, Toronto, Ontario

Centricity Research Toronto Manna Multispecialty, Toronto, Ontario

Manna Research (Toronto), Toronto, Ontario

Diex Recherche Joliette Inc, Joliette, Quebec

Centricity Research Mirabel Multispecialty, Mirabel, Quebec

Clinique de Médecine Urbaine du Quartier Latin, Montreal, Quebec

Alpha Recherche Clinique, Québec, Quebec

Diex Recherche Sherbrooke Inc., Sherbrooke, Quebec

Diex Recherche Joliette Inc., St-Charles-Borromee, Quebec

Diex Recherche Victoriaville Inc., Victoriaville, Quebec

Diex Recherche Quebec Inc., Quebec, Not set

Centre de Recherche Saint-Louis, Quebec, Not set

Diex Recherche Joliette Inc, Quebec, Not set

Espoo Vaccine Research Clinic, Espoo, Not set

FVR, Etelä-Helsingin rokotetutkimusklinikka, Helsinki, Not set

Helsinki East Vaccine Research Clinic, Helsinki, Not set

Terveystalo Jyväskylä, Jyväskylä, Not set

Järvenpää Vaccine Research Clinic, Järvenpää, Not set

Kokkola Vaccine Research Clinic, Kokkola, Not set

Oulu Vaccine Research Clinic, Oulu, Not set

Pori Vaccine Research Clinic, Pori, Not set

Seinäjoki Vaccine Research Clinic, Seinajoki, Not set

Tampere Vaccine Research Clinic, Tampere, Not set

Terveystalo Tampere, Tampere, Not set

Terveystalo Turku Pulssi, Turku, Not set

Turku Vaccine Research Clinic, Turku, Not set

Tenjin General Clinic, Fukuoka-shi, Fukuoka

Seishinkai Inoue Hospital, Itoshima, Fukuoka

Sasaki Clinic, Amagasaki, Hyōgo

Motomachi Takatsuka Naika Clinic, Yokohama, Kanagawa

Medical Corporation Heishinkai OPHAC Hospital, Osaka-shi, Osaka

Sugiura Clinic, Kawaguchi, Saitama

Nihonbashi Sakura Clinic, Chuo-ku, Tokyo

Tokyo Eki Center Building Clinic, Chuo-ku, Tokyo

Fukuwa Clinic, Chuo-ku, Tokyo

Tokyo Asbo Clinic, Chuo-ku, Tokyo

Medical Corp. Seikoukai New Medical Research System Clinic, Hachioji-shi, Tokyo

Hillside Clinic Jingumae, Shibuya-ku, Tokyo

Clinical Research Hospital Tokyo, Shinjuku-ku, Tokyo

Oda Clinic, Shinjuku-ku, Tokyo

Souseikai Sumida Hospital, Sumida-ku, Tokyo

Sekino Hospital, Toshima-ku, Tokyo

SOUSEIKAI PS Clinic, Fukuoka, Not set

AMC Nishiumeda Clinic, Osaka, Not set

Meander Medisch Centrum, Amersfoort, Not set

PoliDirect Amsterdam West, Amsterdam, Not set

Huisartsencentrum Parklaan, Eindhoven, Not set

Huisartsenpraktijk Radesingel, Groningen, Not set

Gezondheidscentrum Leonardus, Helmond, Not set

Spaarne Gasthuis, Hoofddorp, Not set

PoliDirect Nieuwegein, Nieuwegein, Not set

Franciscus Gasthuis & Vlietland, location Gasthuis, Rotterdam, Not set

Huisartsen Soest, Soest, Not set

UMC Utrecht, Utrecht, Not set

Julius Clinical Breda, Zeist, Not set

Josha Research, Bloemfontein, FREE State

Welkom Clinical Trial Centre (MERC WELKOM), Welkom, FREE State

Worthwhile Clinical Trials, Benoni, Gauteng

MERC Research (Pty) Ltd - Kempton, Kempton Park, Gauteng

MERCLINCO (Pty) Ltd - Kempton, Kempton Park, Gauteng

Dr A Jacovides & Partners Inc., Midrand, Gauteng

Newtown Clinical Research Centre (PTY) LTD, Newtown, Gauteng

Emmed Research, Pretoria, Gauteng

Global Clinical Trials, Pretoria, Gauteng

About Allergy, Pretoria, Gauteng

Into Research, Pretoria, Gauteng

Jongaie Research, Pretoria, Gauteng

Synexus SA- Watermeyer Clinical Research Center, Pretoria, Gauteng

Setshaba Research Centre, Soshanguve, Gauteng

Wits Vaccines & Infectious Diseases Analytics, Soweto, Gauteng

FCRN Clinical Trial Centre, Vereeniging, Gauteng

MERC Research (Pty) Ltd - Middelburg, Middelburg, Mpumalanga

Synexus - Helderberg Clinical Research Centre - Somerset West, Cape Town, Western CAPE

TREAD Research, Cape Town, Western CAPE

Be Part Yoluntu Centre, Paarl, Western CAPE

Helderberg Clinical Trials Centre, Somerset West, Western CAPE

Emmed Research, Pretoria, Not set

Botho Ke Bontle Health Services, Pretoria, Not set

Conditions: Lower Respiratory Tract Illness

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