Prednisone for CRPS in Distal Radius Fracture
NCT06453447
Recruiting
Wrist fractures are the most prevalent adult fracture. Complex regional pain syndrome (CRPS) is a common complication that can occur, leading to permanent disability and is costly to the patient and healthcare system. In addition, amidst the opioid epidemic, the risk of increased opioid use in patients with CRPS prompts the need to find viable treatment strategies. This study aims to evaluate an anti-inflammatory medication, prednisone, in the early treatment of CRPS. Patients with wrist fractur... Read More
Gender:
ALL
Ages:
19 years and above
Trial Updated:
11/14/2024
Locations: Vancouver General Hospital, Vancouver, British Columbia
Conditions: Complex Regional Pain Syndromes, Distal Radius Fractures
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Atypical Hemolytic-Uremic Syndrome (aHUS) Registry
NCT01522183
Recruiting
Post-marketing safety data on patients treated and untreated with eculizumab or ravulizumab.
Gender:
ALL
Ages:
All
Trial Updated:
11/13/2024
Locations: Clinical Trial Site, Aurora, Colorado +137 locations
Conditions: Atypical Hemolytic-Uremic Syndrome
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The Combined Use of PRP with Lipoaspirate And/or Bone Marrow Aspirate in Osteoarthritis
NCT03984461
Recruiting
To demonstrate the efficacy of the combined use of platelet-rich plasma (PRP) with lipoaspirate and/or bone marrow aspirate in osteoarthritis of major joints, and to compare the outcomes achieved using three combinations: PRP plus lipoaspirate, PRP plus bone marrow aspirate, and PRP plus both lipoaspirate and bone marrow aspirate.
Gender:
ALL
Ages:
Between 19 years and 79 years
Trial Updated:
11/13/2024
Locations: Pagdin Health, Kelowna, British Columbia
Conditions: Osteoarthritis
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Global Hip Dysplasia Registry
NCT04117685
Recruiting
Developmental dysplasia of the hip (DDH) is the most common hip condition affecting infants and children. DDH represents a spectrum of issues affecting the hip joint - a "ball-and-socket" joint. When the femoral head (the "ball) is seated properly in the acetabulum (the "socket"), the hip is stable and can develop normally. However, when the femoral head is not well-seated, the hip can become unstable or dislocate. This instability or dislocation of the femoral head prevents the hip joint from d... Read More
Gender:
ALL
Ages:
Between 1 minute and 10 years
Trial Updated:
11/13/2024
Locations: British Columbia Children's Hospital, Vancouver, British Columbia
Conditions: Hip Dislocation, Congenital, Hip Dysplasia, Congenital, Nonsyndromic, Congenital Dysplasia of the Hip, Congenital Hip Dislocation, Congenital Hip Displacement, Congenital Hip Dysplasia, Dislocation Of Hip, Congenital, Dislocation, Congenital Hip, Displacement, Congenital Hip, Dysplasia, Congenital Hip, Hip Displacement, Congenital, Hip, Dislocation Of, Congenital
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Post Discharge After Surgery Virtual Care with Remote Automated Monitoring Technology-2 (PVC-RAM-2) Trial
NCT04876950
Recruiting
The Post discharge after surgery Virtual Care with Remote Automated Monitoring technology-2 (PVC-RAM-2) Trial is a multicentre, parallel group, superiority, randomized controlled trial to determine the effect of virtual care with remote automated monitoring (RAM) technology compared to standard care on acute-hospital care during the 45-day follow up after randomization, in adults who have undergone semi-urgent (e.g., oncology), urgent (e.g., hip fracture), or emergency (e.g., ruptured abdominal... Read More
Gender:
ALL
Ages:
40 years and above
Trial Updated:
11/13/2024
Locations: Hamilton General Hospital, Hamilton, Ontario +1 locations
Conditions: Surgery, Perioperative Complication
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Interleaved TMS-fMRI in Ultra-treatment Resistant Depression
NCT05813093
Recruiting
This is a study that will recruit patients from the neurosurgery clinic and the regular TMS clinic. It's a smaller study designed to collect brain imaging pre-treatment and then use image guided TMS to treat patient with a one week "accelerated" rTMS protocol using the research TMS machine that is housed in Dr. Sean Nestor's lab. The idea is to examine whether severe treatment resistant depression has a different brain signature than less severe/TRD and whether the investigators can get a therap... Read More
Gender:
ALL
Ages:
Between 20 years and 65 years
Trial Updated:
11/13/2024
Locations: Sunnybrook Health Sciences Centre, Toronto, Ontario
Conditions: Major Depressive Disorder
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Pharmacokinetics, Pharmacodynamics and Safety of Epeleuton in Patients with Sickle Cell Disease
NCT05861453
Recruiting
To assess the pharmacokinetics, pharmacodynamics and safety of Epeleuton capsules in adult SCD patients who are aged ≥18 years.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/13/2024
Locations: University of Alabama at Birmingham (UAB), Birmingham, Alabama +20 locations
Conditions: Sickle Cell Disease
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Developmental Dysplasia of the Hip: Observation Vs. Bracing
NCT05869851
Recruiting
Developmental dysplasia of the hip (DDH) is the most common childhood hip condition. When caught early, bracing is the most frequently used treatment; however, the brace can disrupt important mother-baby bonding time in the newborn period and present challenges to daily living. In babies with mild DDH, some studies have suggested that their hips may improve naturally as they grow and develop. This study will look at whether careful monitoring can be just as good as bracing for babies diagnosed w... Read More
Gender:
ALL
Ages:
12 weeks and below
Trial Updated:
11/13/2024
Locations: BC Children's Hospital, Vancouver, British Columbia
Conditions: Developmental Dysplasia of the Hip, Hip Dysplasia, Hip Dysplasia, Congenital, Hip Dysplasia, Developmental
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An Evaluation of an Online Sexual Assault Resistance Program (IDEA3)
NCT06058455
Recruiting
The goal of this randomized trial is to test whether the Internet-Delivered Enhanced Assess, Acknowledge, Act (IDEA3) sexual assault resistance education intervention reduces sexual violence victimization in undergraduate women. Participants in the intervention group will be asked to attend four three-hour group sessions of a sexual assault resistance program called IDEA3 with a partner, as well as fill out a number of surveys. Participants in the control group will be asked to attend a one-hou... Read More
Gender:
ALL
Ages:
Between 17 years and 24 years
Trial Updated:
11/13/2024
Locations: University of Michigan, Ann Arbor, Michigan +3 locations
Conditions: Sexual Assault
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Study in Parkinson Disease of Exercise
NCT04284436
Recruiting
This study is a Phase 3 multi-site, randomized, evaluator-masked, study of endurance treadmill exercise on changes in the Movement Disorder Society-Unified Parkinson Disease Rating Scale (MDS-UPDRS) Part III score at 12 months among persons with early stage Parkinson disease. 370 participants will be randomly assigned to 2 groups: 1)60-65% HRmax or 2)80-85% HRmax 4 times per week. The primary objective is to test whether the progression of the signs of Parkinson's disease is attenuated at 12 mon... Read More
Gender:
ALL
Ages:
Between 40 years and 80 years
Trial Updated:
11/12/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama +24 locations
Conditions: Parkinson Disease
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Radiographic Migration Analysis of the ATTUNE Cementless CR Fixed-Bearing Total Knee Replacement
NCT06189872
Recruiting
This is a multi-centre, single cohort trial of patients undergoing cruciate-retaining total knee arthroplasty with the Attune Cementless, Fixed Bearing, Cruciate Retaining TKA System.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
11/12/2024
Locations: Orthopaedic Innovation Centre, Winnipeg, Manitoba +2 locations
Conditions: Osteo Arthritis Knee
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Multiprofen-CC™ to Reduce Pain After Total Knee Arthroplasty
NCT06202989
Recruiting
Total knee arthroplasty is a surgical treatment which involves replacing the damaged articular cartilage of the knee joint with an artificial prosthetic in end-stage knee osteoarthritis. Although total knee arthroplasties are mostly successful, approximately 1 in 5 patients are unsatisfied with their outcomes with 16-33% of patients of patients experiencing lasting pain following total knee arthroplasty. Multiprofen-CC™ is a compounded topical analgesic currently available to healthcare profess... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/12/2024
Locations: St. Joseph's Healthcare Hamilton, Hamilton, Ontario +1 locations
Conditions: Postsurgical Pain
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