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All Clinical Trials in Canada
A listing of 3905 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
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Sacituzumab Tirumotecan (MK-2870) Versus Pemetrexed and Carboplatin Combination Therapy in Participants With Epidermal Growth Factor (EGFR)-Mutated, Advanced Nonsquamous Non-small Cell Lung Cancer (NSCLC) Who Have Progressed on Prior EGFR Tyrosine Kinase Inhibitors (MK-2870-009)
Recruiting
The purpose of this study is to evaluate sacituzumab tirumotecan versus pemetrexed in combination with carboplatin for the treatment of epidermal growth factor receptor (EGFR)-mutated advanced non-squamous non-small cell lung cancer (NSCLC). Participants in this study have NSCLC that has continued to progress on prior treatment with EGFR tyrosine kinase inhibitors (TKIs).
The primary hypotheses of this study are that sacituzumab tirumotecan is better than platinum-based doublet chemotherapy (pe... Read More
The purpose of this study is to evaluate sacituzumab tirumotecan versus pemetrexed in combination with carboplatin for the treatment of epidermal growth factor receptor (EGFR)-mutated advanced non-squamous non-small cell lung cancer (NSCLC). Participants in this study have NSCLC that has continued to progress on prior treatment with EGFR tyrosine kinase inhibitors (TKIs).
The primary hypotheses of this study are that sacituzumab tirumotecan is better than platinum-based doublet chemotherapy (pemetrexed and carboplatin) in regard to progression-free survival (PFS) and overall survival (OS). Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/14/2025
Locations: Kaiser Permanente - Oakland ( Site 0054), Oakland, California +152 locations
Kaiser Permanente - Oakland ( Site 0054), Oakland, California
Kaiser Permanente - Roseville ( Site 0055), Roseville, California
Kaiser Permanente - San Francisco ( Site 0056), San Francisco, California
Kaiser Permanente - Santa Clara ( Site 0057), Santa Clara, California
Kaiser Permanente-Kaiser Permanente ( Site 0036), Vallejo, California
Kaiser Permanente - Walnut Creek ( Site 0058), Walnut Creek, California
Mid Florida Hematology and Oncology Center ( Site 0005), Orange City, Florida
Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital-Research ( Site 0003), Marietta, Georgia
University of Michigan ( Site 0009), Ann Arbor, Michigan
Cox Medical Center North - Cox Medical Center/ Hematology/Medical Oncology ( Site 0051), Springfield, Missouri
Astera Cancer Care ( Site 0032), East Brunswick, New Jersey
Stony Brook University-Cancer Center ( Site 0038), Stony Brook, New York
Sanford Fargo Medical Center ( Site 0028), Fargo, North Dakota
Sanford Cancer Center ( Site 0024), Sioux Falls, South Dakota
Millennium Research & Clinical Development ( Site 0035), Houston, Texas
Clinica Adventista Belgrano-Oncology ( Site 0315), Caba., Buenos Aires
Instituto Alexander Fleming ( Site 0307), Ciudad Autónoma de Buenos Aires, Buenos Aires
Hospital Británico de Buenos Aires-Oncology ( Site 0304), Ciudad autónoma de Buenos Aires, Caba
Centro Privado de RMI Río Cuarto S.A. II ( Site 0310), Río Cuarto, Cordoba
Instituto de Oncología de Rosario ( Site 0301), Rosario, Santa Fe
Fundación CORI para la Investigación y Prevención del Cáncer ( Site 0303), La Rioja, Not set
Cross Cancer Institute ( Site 0201), Edmonton, Alberta
Waterloo Regional Health Network (WRHN) ( Site 0207), Kitchener, Ontario
Princess Margaret Cancer Centre ( Site 0203), Toronto, Ontario
McGill University Health Centre ( Site 0204), Montréal, Quebec
Anhui Provincial Cancer Hospital ( Site 3132), Hefei, Anhui
Beijing Cancer hospital ( Site 3100), Beijing, Beijing
Beijing Peking Union Medical College Hospital-pneumology department ( Site 3107), Beijing, Beijing
Chongqing University Cancer Hospital-Medical Oncology ( Site 3128), Chongqing, Chongqing
Fujian Cancer Hospital ( Site 3124), Fuzhou, Fujian
The First Affiliated hospital of Xiamen University ( Site 3125), XiaMen, Fujian
Southern Medical University Nanfang Hospital-Depatrment of Respiratory and Critical Care Medicine ( Site 3102), Guangzhou, Guangdong
Guangxi Medical University Affiliated Tumor Hospital-Respiratory Oncology ( Site 3103), Nanning, Guangxi
Harbin Medical University Cancer Hospital ( Site 3109), Harbin, Heilongjiang
Henan Cancer Hospital ( Site 3105), Zhengzhou, Henan
Tongji Hospital Tongji Medical,Science & Technology ( Site 3121), Wuhan, Hubei
Hubei Cancer Hospital ( Site 3122), Wuhan, Hubei
The Second Xiangya Hospital of Central South University-Oncology ( Site 3104), Changsha, Hunan
Nanjing Drum Tower Hospital JiangBei International Branch Hospital ( Site 3117), Nanjing, Jiangsu
The First Affiliated Hospital of Soochow University-Respiratory Department ( Site 3118), Suzhou, Jiangsu
The Second Affiliated Hospital of Nanchang University ( Site 3119), Nanchang, Jiangxi
The Second Affiliated Hospital of Xi'an Jiaotong University ( Site 3130), XI An, Shaanxi
Jinan Central Hospital ( Site 3113), Jinan, Shandong
Shandong Cancer Hospital ( Site 3112), Jinan, Shandong
Zhongshan Hospital of Fudan University ( Site 3133), Shanghai, Shanghai
Shanxi Cancer Hospital ( Site 3114), Taiyuan, Shanxi
West China Hospital, Sichuan University ( Site 3126), Cheng Du, Sichuan
Sichuan Cancer hospital. ( Site 3127), Chengdu, Sichuan
The first Affiliated Hospital, Zhejiang University School of Medicine ( Site 3101), Hangzhou, Zhejiang
Sir Run Run Shaw Hospital of Zhejiang University School of Medicine-Medical Oncology ( Site 3106), Hangzhou, Zhejiang
The First Affiliated Hospital of Wenzhou Medical University-Respiratory department ( Site 3120), Wenzhou, Zhejiang
Sociedad de Oncología Y Hematología del Cesar S.A.S. ( Site 0601), Valledupar, Cesar
IMAT S.A.S ( Site 0602), Monteria, Cordoba
FUNDACION CTIC CENTRO DE TRATAMIENTO E INVESTIGACION SOBRE CANCER LUIS CARLOS SARMIENTO ANGULO ( Site 0600), Bogota, Distrito Capital De Bogota
Clinica Colsanitas S.A, Sede Clínica Universitaria Colombia-Center Investigator ( Site 0606), Bogota, Distrito Capital De Bogota
Oncologos del Occidente ( Site 0604), Pereira., Risaralda
Fundacion Valle del Lili- CIC-Oncology CIC ( Site 0605), Cali, Valle Del Cauca
Nouvel Hôpital Civil (NHC) ( Site 1302), Strasbourg, Alsace
Clinique Clairval ( Site 1306), Marseille, Bouches-du-Rhone
Gustave Roussy ( Site 1303), Villejuif, Ile-de-France
Hopitaux Universitaires Paris Centre-Hopital Cochin-Unité d'Oncologie Thoracique ( Site 1304), Paris, Not set
All India Institute of Medical Sciences-Department of medical oncology ( Site 3303), New Delhi, Delhi
Indraprastha Apollo Hospitals-APOLLO RESEARCH INNOVATION ( Site 3301), New Delhi, Delhi
Rajiv Gandhi Cancer Institute And Research Centre ( Site 3300), New Delhi, Delhi
Artemis hospital ( Site 3307), Gurugram, Haryana
Kokilaben Dhirubhai Ambani Hospital & Medical Research Institute-Centre for cancer ( Site 3302), Mumbai, Maharashtra
Istituto Europeo di Oncologia IRCCS-Divisione di Oncologia Toracica ( Site 1803), Milano, Lombardia
Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Oncologia Medica 1 ( Site 1800), Milan, Lombardia
Instituto Tumori Giovanni Paolo II-SSD Oncologia Medica per la Patologia Toracica ( Site 1802), Bari, Puglia
Azienda Ospedaliera Universitaria Careggi-SOD ONCOLOGIA MEDICA ( Site 1804), Firenze, Toscana
Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore ( Site 1801), Roma, Not set
Fujita Health University Hospital ( Site 3409), Toyoake, Aichi
Ehime University Hospital ( Site 3411), Toon, Ehime
National Hospital Organization Kyushu Cancer Center ( Site 3401), Fukuoka,, Fukuoka
Gunma Prefectural Cancer Center ( Site 3413), Ota, Gunma
Kanazawa University Hospital ( Site 3402), Kanazawa, Ishikawa
St. Marianna University Hospital ( Site 3415), Kawasaki, Kanagawa
Kanagawa Cancer Center ( Site 3416), Yokohama, Kanagawa
Miyagi Cancer Center ( Site 3406), Natori, Miyagi
Kansai Medical University Hospital ( Site 3414), Hirakata, Osaka
Saitama Prefectural Cancer Center ( Site 3417), Kitaadachi-gun, Saitama
Shizuoka Cancer Center ( Site 3405), Sunto-gun, Shizuoka
National Cancer Center Hospital ( Site 3408), Chuo, Tokyo
Toho University Omori Medical Center ( Site 3407), Ota, Tokyo
Kyushu University Hospital ( Site 3400), Fukuoka, Not set
Hiroshima City Hiroshima Citizens Hospital ( Site 3419), Hiroshima, Not set
Niigata Cancer Center Hospital ( Site 3403), Niigata, Not set
Okayama University Hospital ( Site 3404), Okayama, Not set
Osaka International Cancer Institute ( Site 3410), Osaka, Not set
Osaka Metropolitan University Hospital ( Site 3412), Osaka, Not set
Chungbuk National University Hospital ( Site 3804), Cheongju-si, Chungbuk
National Cancer Center ( Site 3803), Goyang-si, Kyonggi-do
Seoul National University Bundang Hospital ( Site 3807), Seongnam, Kyonggi-do
The Catholic University Of Korea St. Vincent's Hospital ( Site 3800), Suwon-si, Kyonggi-do
Ajou University Hospital ( Site 3813), Suwon, Kyonggi-do
Pusan National University Yangsan Hospital ( Site 3802), Pusan, Kyongsangnam-do
Pusan National University Hospital ( Site 3805), Busan, Pusan-Kwangyokshi
Keimyung University Dongsan Hospital CRC room 1 ( Site 3814), Daegu, Taegu-Kwangyokshi
Chungnam national university hospital ( Site 3806), Jung-gu, Taejon-Kwangyokshi
The Catholic University of Korea, Eunpyeong St. Mary's Hospital ( Site 3812), Seoul, Not set
Asan Medical Center ( Site 3810), Seoul, Not set
Samsung Medical Center ( Site 3811), Seoul, Not set
Korea University Guro Hospital ( Site 3808), Seoul, Not set
University Malaya Medical Centre ( Site 3507), Lembah Pantai, Kuala Lumpur
National Cancer Institute-Radiotherapy and Oncology ( Site 3504), Putrajaya, Kuala Lumpur
Hospital Tengku Ampuan Afzan ( Site 3506), Kuantan, Pahang
Hospital Pulau Pinang-Oncology, radiotherapy and palliat ( Site 3501), George Town, Pulau Pinang
Sarawak General Hospital-Radiotherapy Unit ( Site 3508), Kuching, Sarawak
Arké SMO S.A. de C.V. ( Site 0706), Mexico, Distrito Federal
CIO - Centro de Inmuno-Oncología de Occidente ( Site 0700), Guadalajara, Jalisco
Hospital Universitario "Dr. Jose Eleuterio Gonzalez"-Servicio de Oncología ( Site 0705), Monterrey, Nuevo Leon
Centro de Investigacion Clinica de Oaxaca ( Site 0704), Oaxaca de Juarez, Oaxaca
Oaxaca Site Management Organization S.C. ( Site 0701), Oaxaca, Not set
Centrum Onkologii im. Prof. Franciszka Lukaszczyka-Ambulatorium Chemioterapii ( Site 2003), Bydgoszcz, Kujawsko-pomorskie
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Klinika Nowotworow Pluca i Klatki Pier ( Site 2000), Warszawa, Mazowieckie
Bialostockie Centrum Onkologii ( Site 2010), Bialystok, Podlaskie
Narodowy Instytut Onkologii - Oddzial w Gliwicach-II Klinika Radioterapi i Chemioterapii ( Site 2002), Gliwice, Slaskie
Institut Català d'Oncologia - L'Hospitalet-Medical Oncology ( Site 2321), LHospitalet de Llobregat, Barcelona
CHUS - Hospital Clinico Universitario-Servicio de Oncologia ( Site 2322), Santiago de compostela, La Coruna
Hospital Universitario Juan Ramon Jimenez-Oncología Medica ( Site 2323), Huelva, Not set
Hospital Universitario Virgen Macarena-Unidad de Investigación Oncológica ( Site 2324), Sevilla, Not set
Karolinska Universitetssjukhuset Solna ( Site 2401), Stockholm, Stockholms Lan
National Cheng Kung University Hospital ( Site 3901), Tainan City, Tainan
Chi Mei Hospital - Liouying Branch ( Site 3909), Tainan City, Tainan
National Taiwan University Cancer Center (NTUCC) ( Site 3907), Taipei City, Taipei
Changhua Christian Hospital ( Site 3904), Changhua, Not set
National Taiwan University Hospital - Hsinchu branch ( Site 3900), Hsinchu, Not set
Chang Gung Memorial Hospital at Kaohsiung ( Site 3905), Kaohsiung, Not set
Far Eastern Memorial Hospital ( Site 3912), New Taipei, Not set
Taichung Veterans General Hospital-Chest ( Site 3910), Taichung, Not set
National Taiwan University Hospital-Oncology ( Site 3908), Taipei, Not set
Mackay Memorial Hospital-Chest Medicine ( Site 3902), Taipei, Not set
Taipei Medical University Hospital ( Site 3903), Taipei, Not set
Chang Gung Medical Foundation-Linkou Branch-Clinic of Chest Medicine ( Site 3911), Taoyuan, Not set
Maharaj Nakorn Chiang Mai Hospital ( Site 4005), Muang, Chiang Mai
Faculty of Medicine - Khon Kaen University ( Site 4002), Muang, Khon Kaen
Faculty of Medicine Siriraj Hospital ( Site 4004), Bangkok, Krung Thep Maha Nakhon
Bangkok Metropolitan Administration Medical College and Vajira Hospital ( Site 4006), Dusit, Krung Thep Maha Nakhon
Ramathibodi Hospital ( Site 4001), Ratchathewi, Krung Thep Maha Nakhon
Lampang Cancer Hospital ( Site 4000), Mueang Lampang, Lampang
Songklanagarind hospital ( Site 4003), HatYai, Songkhla
Adana Medical Park Seyhan Hastanesi-Medikal Onkoloji ( Site 2504), Adana, Not set
Hacettepe Universite Hastaneleri-oncology hospital ( Site 2501), Ankara, Not set
Memorial Ankara Hastanesi-Medical Oncology ( Site 2505), Ankara, Not set
Ankara Bilkent Şehir Hastanesi ( Site 2500), Ankara, Not set
I.E.U. Medical Point Hastanesi-Oncology ( Site 2503), Izmir, Not set
Hanoi Oncology Hospital ( Site 4198), Hanoi, Ha Noi
K Hospital - National Cancer Hospital ( Site 4193), Hanoi, Ha Noi
National Lung Hospital-Oncology Department ( Site 4194), Hanoi, Ha Noi
Thong Nhat Hospital ( Site 4192), Tan Binh District, Ho Chi Minh
Cho Ray Hospital ( Site 4190), Ho Chi Minh, Not set
Ho Chi Minh City Oncology Hospital - Tan Phu Ward ( Site 4191), Ho Chi Minh, Not set
Tam Anh Hospital ( Site 4196), Ho Chi Minh, Not set
Conditions: Non-small Cell Lung Cancer (NSCLC)
A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
Recruiting
Researchers are looking for new ways to treat people with proficient mismatch repair (pMMR) endometrial cancer (EC) that is advanced or recurrent.
* EC is a type of cancer that starts in the tissues inside the uterus (womb)
* pMMR indicates that certain normal proteins are present in the cancer cells
* Advanced means the cancer has spread locally or to other parts of the body (metastatic) and cannot be removed with surgery
* Recurrent means the cancer came back after surgery
Sacituzumab tirumo... Read More
Researchers are looking for new ways to treat people with proficient mismatch repair (pMMR) endometrial cancer (EC) that is advanced or recurrent.
* EC is a type of cancer that starts in the tissues inside the uterus (womb)
* pMMR indicates that certain normal proteins are present in the cancer cells
* Advanced means the cancer has spread locally or to other parts of the body (metastatic) and cannot be removed with surgery
* Recurrent means the cancer came back after surgery
Sacituzumab tirumotecan (also known as sac-TMT) and pembrolizumab are the study medicines. Sac-TMT is an antibody drug conjugate (ADC). An ADC attaches to specific targets on cancer cells and delivers treatment to destroy those cells.
The goal of this study is to learn if people who receive sac-TMT with pembrolizumab live longer and without the cancer getting worse compared to people who receive pembrolizumab alone. Read Less
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
08/14/2025
Locations: Mount Sinai Cancer Center ( Site 6031), Miami Beach, Florida +20 locations
Mount Sinai Cancer Center ( Site 6031), Miami Beach, Florida
TRIALS 365 ( Site 6005), Shreveport, Louisiana
Miami Valley Hospital South ( Site 6014), Centerville, Ohio
Oklahoma Cancer Specialists and Research Institute, LLC ( Site 6047), Tulsa, Oklahoma
Texas Oncology - DFW ( Site 8004), Fort Worth, Texas
Instituto de Investigaciones Clínicas Mar del Plata ( Site 0108), Mar del Plata, Buenos Aires
Fundación Respirar ( Site 0101), Buenos Aires, Caba
Centre Hospitalier de l Universite de Montreal - CHUM ( Site 0605), Montreal, Quebec
ONCOCENTRO APYS ( Site 0704), Vina del Mar, Valparaiso
Rambam Health Care Campus ( Site 2025), Haifa, Not set
Carmel Hospital ( Site 2023), Haifa, Not set
Shaare Zedek Medical Center ( Site 2020), Jerusalem, Not set
Sourasky Medical Center ( Site 2022), Tel Aviv, Not set
Keimyung University Dongsan Hospital ( Site 3105), Daegu, Taegu-Kwangyokshi
Asan Medical Center ( Site 3103), Seoul, Not set
Puerto Rico Cancer Specialists Clinical Trials ( Site 4201), San Juan, Not set
National Cancer Centre Singapore ( Site 3201), Singapore, Central Singapore
Taichung Veterans General Hospital ( Site 3703), Taichung, Not set
National Taiwan University Hospital ( Site 3701), Taipei, Not set
Mackay Memorial Hospital ( Site 3704), Taipei, Not set
Linkou Chang Gung Memorial Hospital ( Site 3705), Taoyuan, Not set
Conditions: Endometrial Cancer
Pan Tumor Rollover Study
Recruiting
Main Objective of this study is to examine long-term safety of nivolumab monotherapy including combinations and other cancer therapies in various tumor types.
Main Objective of this study is to examine long-term safety of nivolumab monotherapy including combinations and other cancer therapies in various tumor types. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/14/2025
Locations: Local Institution - 0220, Huntsville, Alabama +395 locations
Local Institution - 0220, Huntsville, Alabama
University of Arizona College of Medicine, Tucson, Arizona
Innovative Clinical Research Institute, Lynwood, California
Local Institution, San Francisco, California
Local Institution - 0099, San Francisco, California
Local Institution - 0233, Aurora, Colorado
Local Institution - 0095, New Haven, Connecticut
Local Institution - 0088, Washington, District of Columbia
Florida Cancer Affiliates, Ocala, Florida
Local Institution, Orlando, Florida
Local Institution - 0024, Tampa, Florida
Local Institution - 0105, Chicago, Illinois
Local Institution, Maywood, Illinois
Local Institution - 0279, Park Ridge, Illinois
Local Institution - 0186, Westwood, Kansas
Local Institution - 0165, Wichita, Kansas
University of Louisville-James Graham Brown Cancer Center, Louisville, Kentucky
Local Institution - 0092, Baltimore, Maryland
Local Institution - 0039, Boston, Massachusetts
Dana_Farber Cancer Institute (DFCI), Boston, Massachusetts
Local Institution - 0081, Boston, Massachusetts
Local Institution - 0143, Ann Arbor, Michigan
Local Institution - 0100, Minneapolis, Minnesota
Local Institution, Saint Louis, Missouri
Local Institution - 0205, Omaha, Nebraska
Local Institution - 0014, Lebanon, New Hampshire
Local Institution, Albuquerque, New Mexico
Roswell Park Cancer Institute, Buffalo, New York
Local Institution - 0413, Mineola, New York
Local Institution, New York, New York
Local Institution - 0185, New York, New York
Local Institution - 0202, New York, New York
Local Institution, New York, New York
Local Institution - 0204, Charlotte, North Carolina
Local Institution - 0016, Durham, North Carolina
Oncology Hematology Care, Cincinnati, Ohio
Local Institution - 0408, Cincinnati, Ohio
Local Institution, Cleveland, Ohio
The Ohio University, Columbus, Ohio
Local Institution - 0246, Tulsa, Oklahoma
Local Institution - 0037, Allentown, Pennsylvania
Local Institution - 0054, Easton, Pennsylvania
Lancaster General Health, Lancaster, Pennsylvania
Allegheny Valley Hospital, Natrona Heights, Pennsylvania
Local Institution, Philadelphia, Pennsylvania
Local Institution - 0162, Philadelphia, Pennsylvania
Local Institution - 0110, Pittsburgh, Pennsylvania
Local Institution - 0228, Charleston, South Carolina
Local Institution, Greenville, South Carolina
Local Institution, Chattanooga, Tennessee
Tennesse Oncology, Nashville, Tennessee
Vanderbilt University Medical Center, Nashville, Tennessee
Local Institution, Dallas, Texas
Local Institution - 0364, Houston, Texas
Local Institution - 0055, Salt Lake City, Utah
Local Institution, Charlottesville, Virginia
Public Hospital of King County District 1 Valley Medical Center, Renton, Washington
Local Institution - 0065, Madison, Wisconsin
Local Institution - 0124, Madison, Wisconsin
Local Institution - 0199, Berazategui, Buenos Aires
Local Institution - 0415, Rio Cuarto, Cordoba
Local Institution - 0405, Viedma, Rio Negro
Local Institution - 0407, Rosario, Santa Fe
Local Institution - 0191, San Miguel De Tucumán, Tucuman
CAIPO Centro para la Atencion Integral del Paciente Oncologico, San Miguel De Tucumán, Tucumán
Local Institution - 0201, Buenos Aires, Not set
Instituto Fleming, Buenos Aires, Not set
Local Institution, Caba, Not set
Fundacion Richardet Longo - IONC, Cordoba, Not set
Local Institution - 0170, Cordoba, Not set
Local Institution - 0045, Coffs Harbour, New South Wales
Melanoma Institute Australia, North Sydney, New South Wales
Chris OBrien Lifehouse Hospital, Sydney, New South Wales
Local Institution - 0193, Waratah, New South Wales
Local Institution - 0208, Westmead, New South Wales
Gallipoli Medical Foundation, Greenslopes, Queensland
Local Institution - 0372, Greenslopes, Queensland
Local Institution, South Brisbane, Queensland
Tasman Oncology Research Ltd, Southport, Queensland
Local Institution, Adelaide, South Australia
Local Institution - 0196, Elizabeth Vale, South Australia
Local Institution - 0411, Ballarat, Victoria
Local Institution - 0365, Fitzroy, Victoria
Cabrini Hospital Malvern, Malvern, Victoria
Local Institution - 0174, Murdoch, Western Australia
Local Institution - 0254, Graz, Steiermark
Ordensklinikum Linz GmbH Elisabethinen, Linz, Upper Austria
Local Institution - 0104, Vienna, Not set
Local Institution - 0145, Wels, Not set
Allgemeines Krankenhaus Wien, Wien, Not set
Local Institution - 0329, Brussel, Not set
Local Institution - 0232, Gent, Not set
Local Institution - 0139, Jette, Not set
Local Institution - 0261, Liege, Not set
Local Institution - 0293, Sint-Niklaas, Not set
Cliniques Universitaires UCL de Mont-Godinne (CHU), Yvoir, Not set
Local Institution - 0260, Belo Horizonte, Minas Gerais
ONCOSITE - Centro de Pesquisa Clinica em Oncologia, Ijui, RIO Grande DO SUL
Local Institution - 0093, Porto Alegre, Rio Grande Do Sul
Irmandade da Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Rio Grande Do Sul
Hospital Sao Lucas Da Pucrs, Porto Alegre, Rio Grande Do Sul
Local Institution - 0379, Passo Fundo, RS
Local Institution - 0399, Porto Alegre, RS
Local Institution - 0264, Barretos, Sao Paulo
Local Institution - 0262, Sao Jose do Rio Preto, Sao Paulo
Local Institution - 0263, São Paulo, SAO Paulo
ICESP - Instituto do Cancer do Estado de Soo Paulo, Sao Paulo, SP
Hospital Alemao Oswaldo Cruz, Sao Paulo, SP
Local Institution - 0266, Rio De Janeiro, Not set
Local Institution - 0258, Rio De Janeiro, Not set
Local Institution - 0340, Sao Paulo, Not set
Cross Cancer Institute, Edmonton, Alberta
Local Institution, Vancouver, British Columbia
Local Institution, Halifax, Nova Scotia
Local Institution - 0168, Oshawa, Ontario
Princess Margaret Cancer Centre, Toronto, Ontario
Local Institution - 0040, Montreal, Quebec
Local Institution - 0308, Montreal, Quebec
Local Institution - 0363, Temuco, Araucania
Local Institution - 0398, Providencia, Metropolitana
Bradford Hill Centro de Investigacion Clinica, Santiago de Chile, Metropolitana
Fundacion Arturo Lopez Perez, Santiago, Metropolitana
Local Institution, Santiago, Metropolitana
Local Institution - 0079, Vina Del Mar, Not set
Local Institution - 0169, Hefei, Anhui
Local Institution - 0198, Beijing, Beijing
Local Institution, Guangzhou, Guangdong
Nanfang Hospital; Southern Medical University, Guangzhou, Guangdong
Local Institution - 0160, Harbin Shi, Heilongjiang
Local Institution - 0245, Harbin, Heilongjiang
Harbin Medical University - Cancer Hospital, Harbin, Heilongjiang
Local Institution - 0172, Changsha, Hunan
Xiangya Hospital Central South University, Changsha, Hunan
Hunan Cancer Hospital, Changsha, Hunan
Local Institution - 0348, Nanjing, Jiangsu
Jilin University (JLU) - First Affiliated Hospital - Cancer Center, Changchun, Jilin
Jilin Cancer Hospital, Changchun, Jilin
Tangdu Hospital of Fourth Military Medical University, Xian, Shaanxi
Xian International Medical Center Hospital, Xian, Shan3XI
Ruijin Hospital Shanghai Jiaotong University School of Medicine, Shanghai, Shanghai
Fudan University - Shanghai Cancer Center FUSCC, Shanghai, Shanghai
Local Institution - 0278, Shanghai, Shanghai
Local Institution - 0325, Shanghai, Shanghai
Local Institution - 0188, Shanghai, Shanghai
Sir Run Run Shaw Hospital, Hangzhou, Zhejiang
The First Affiliated Hospital Zhejiang University (The First Hospital of Zhejiang Province), Hangzhou, Not set
Local Institution - 0390, Nanjing, Not set
Local Institution - 0371, Brno, Not set
FNHK Klinika onkologie a radioterapie, Hradec Kralove, Not set
Local Institution - 0150, Olomouc, Not set
Local Institution - 0275, Prague, Not set
Local Institution, Odense C, Not set
Local Institution, Helsinki, Not set
Local Institution - 0006, Bordeaux, Gironde
Local Institution - 0387, Paris, Ile De France
CHU De Nancy Hopital De Brabois, Vandoeuvre-Les-Nancy, Meurthe-Et-Moselle
Centre Jean Perrin, Clermont-Ferrand, Not set
Local Institution - 0107, Creteil, Not set
Local Institution - 0074, Dijon Cedex, Not set
Centre Georges-Francois Leclerc, Dijon, Not set
CHU Grenobles Alpes, La Tronche, Not set
Pole Biologie Pathologie Genetique - CHU de Lille, Lille Cedex, Not set
Local Institution - 0153, Marseille Cedex 20, Not set
APHM - Hopital de la Timone, Marseille, Not set
CHU Montpellier, Montpellier, Not set
Local Institution, Montpellier, Not set
CHU Nantes - Hotel Dieu, Nantes Cedex 1, Not set
Local Institution - 0300, Nantes, Not set
Local Institution - 0167, Paris Cedex 15, Not set
Local Institution - 0028, Paris, Not set
Local Institution - 0301, Paris, Not set
Centre Hospitalier Lyon Sud, Pierre-Benite Cedex, Not set
Local Institution, Rennes, Not set
CHU de Saint-Etienne - Hopital Nord, Saint-Priest en Jarez, Not set
Local Institution - 0392, Suresnes, Not set
Local Institution - 0156, Toulon, Not set
Local Institution, Toulouse Cedex, Not set
Institut Gustave Roussy, Villejuif Cedex, Not set
Local Institution - 0386, Loewenstein, Baden Wuerttemberg
Local Institution - 0276, Muenchen, Bayern
Local Institution - 0332, Nuremberg, Bayern
Local Institution - 0250, Essen, Nordrhein-Westfalen
Local Institution - 0375, Essen, Nordrhein-westfalen
Local Institution - 0402, Essen, NRW
Universitaetsklinikum Aachen, Aachen, Not set
Local Institution - 0248, Berlin, Not set
Local Institution - 0249, Buxtehude, Not set
Local Institution - 0296, Cologne, Not set
University of Freiburg, Freiburg, Not set
Local Institution, Gera, Not set
SRH Wald-Klinikum Gera GmbH, Gera, Not set
Local Institution, Goettingen, Not set
Local Institution - 0076, Gottingen, Not set
Local Institution - 0241, Hamburg, Not set
Local Institution, Heidelberg, Not set
Thoraxklinik, Heidelberg, Not set
Local Institution - 0342, Heidelberg, Not set
SLK-Kliniken Heilbronn GmbH, Heilbronn, Not set
Universitaetsklinikum Jena - Klinik und Poliklinik fuer Urologie, Jena, Not set
Local Institution - 0288, Kassel, Not set
Local Institution - 0072, Kiel, Not set
Local Institution, Kiel, Not set
Local Institution, Koeln, Not set
Local Institution - 0298, Loewenstein, Not set
Local Institution - 0098, Luebeck, Not set
Local Institution - 0089, Mainz, Not set
Local Institution, Mainz, Not set
Local Institution - 0017, Tubingen, Not set
Local Institution - 0277, Tuebingen, Not set
Local Institution - 0381, Athens, Attica
Local Institution - 0244, Heraklion, Crete
General Hospital of Athens Laiko, Athens, Not set
Local Institution - 0126, Athens, Not set
Local Institution - 0171, Athens, Not set
Local Institution - 0042, Athens, Not set
Local Institution - 0295, Athens, Not set
Local Institution, Patras, Not set
Local Institution - 0215, Thessaloniki, Not set
Queen Mary Hospital, Hong Kong, Not set
Local Institution - 0290, Gyongyossolymos, Heves
Local Institution - 0159, Budapest, Not set
Local Institution - 0226, Budapest, Not set
Local Institution - 0187, Debrecen, Not set
Local Institution - 0227, Dublin, Not set
Local Institution, Limerick, Not set
Local Institution - 0190, Haifa, Not set
Local Institution - 0270, Jerusalem, Not set
Local Institution, Petach Tikva, Not set
Sheba Medical Center, Ramat Gan, Not set
Local Institution - 0350, Tiqwa, Not set
IRCCS - Istituto Scientifico Romagnolo per lo Studio dei Tumori - Dino Amadori - Srl, Meldola, Fc
Local Institution - 0333, Rozzano, MI
Istituto Nazionale dei Tumori Regina Elena, Roma, RM
Local Institution - 0034, Bari, Not set
ASST Papa Giovanni XXIII, Bergamo, Not set
Local Institution - 0326, Candiolo, Not set
"Azienda Ospedaliero - Universitaria ""Policlinico-Vittorio Emanuele"" - Ospedale Gaspare Rodolico", Catania, Not set
Local Institution - 0251, Genova, Not set
Local Institution, Genova, Not set
Local Institution - 0108, Meldola, Not set
Local Institution - 0303, Meldola, Not set
Local Institution, Milano, Not set
IRCCS Istituto Europeo di Oncologia, Milano, Not set
Local Institution - 0071, Milano, Not set
Local Institution, Milano, Not set
Fondazione IRCCS istituto Neurologico Carlo Besta;, Milan, Not set
Local Institution - 0096, Milan, Not set
Local Institution - 0351, Milan, Not set
Local Institution - 0327, Modena, Not set
Istituto Nazionale Tumori - Fondazione Pascale Italy, Napoli, Not set
Local Institution - 0218, Napoli, Not set
Local Institution - 0292, Napoli, Not set
Istituto Oncologico Veneto, Padova, Not set
AUSL Romagna, Ravenna, Not set
Local Institution - 0003, Siena, Not set
Local Institution - 0291, Terni, Not set
Azienda Ospedaliera Citta della Salute e della Scienza, Torino, Not set
Local Institution - 0242, Hirosaki-shi, Aomori
Chiba Cancer Center, Chiba-shi, Chiba
National Cancer Center Hospital East, Kashiwa-Shi, Chiba
Ehime Prefectural Central Hospital, Matsuyama-shi, Ehime
Local Institution - 0397, Matsuyama-shi, Ehime
Kyushu University Hospital, Fukuoka-shi, Fukuoka
Local Institution - 0211, Kobe shi, Hyogo
Local Institution - 0240, Tsukuba, Ibaraki
Local Institution - 0219, Kanazawa-shi, Ishikawa
Yokohama City University Medical Center, Yokohama, Kanagawa
Local Institution - 0222, Natori, Miyagi
Local Institution - 0230, Niigata-City, Niigata
Local Institution - 0214, Osakasayama, Osaka
Local Institution - 0212, Takatsuki, Osaka
Hamamatsu University Hospital, Hamamatsu, Shizuoka
Tokyo Women's Medical University - Adachi Medical Center, Adachi-Ku, Tokyo
Institute of Science Tokyo Hospital, Bunkyo-Ku, Tokyo
Local Institution - 0235, Chuo-ku, Tokyo
Local Institution - 0217, Koto-Ku, Tokyo
Local Institution - 0239, Shinjuku, Tokyo
Local Institution - 0224, Fukuoka, Not set
Hiroshima University Hospital, Hiroshima, Not set
Local Institution - 0236, Niigata, Not set
Local Institution - 0389, Seongnam, Gyeonggi-do
Asan Medical Center, Seoul, Songpa-gu
National Cancer Center, Gyeonggi-do, Not set
Local Institution - 0221, Seongnam-si, Not set
Local Institution - 0206, Seoul, Not set
Seoul National University Hospital, Seoul, Not set
Local Institution - 0207, Suwon Si, Not set
Local Institution - 0410, Mexico City, Cdmx
Local Institution - 0181, Tlalpan, Ciudad De Mexico
Local Institution - 0152, Leon, Guanajuato
Local Institution - 0338, Zapopan, Jalisco
Hospital Victoria Medical Center, Morelia, Michoacan
Local Institution - 0286, Monterrey, Nuevo Leon
Local Institution - 0354, Monterrey, Nuevo Leon
Local Institution - 0396, Monterrey, Nuevo LEON
Centro de Investigacion Clinica de Oaxaca, Oaxaca de Juarez, Oaxaca
Local Institution - 0343, Santiago de Queretaro, Queretaro
Local Institution - 0344, Ciudad de Mexico, Not set
Local Institution - 0346, Ciudad de Mexico, Not set
Local Institution - 0337, Ciudad de Mexico, Not set
Local Institution - 0367, San Luis Potosi, Not set
Local Institution - 0335, Amsterdam, Noord-Holland
Local Institution, Rotterdam, Not set
Auckland City Hospital-Liver Research Unit, Auckland, Not set
Local Institution - 0271, Christchurch, Not set
Local Institution - 0268, Dunedin, Not set
Local Institution - 0269, Tauranga, Not set
Local Institution - 0213, Bergen, Not set
Local Institution - 0048, Oslo, Not set
Local Institution - 0179, Santiago de Surco, Lima
Local Institution - 0385, Lima, Not set
Centrum Onkologii im. Prof. Franciszka Lukaszczyka, Bydgoszcz, Kujawsko-pomorskie
Local Institution - 0336, Biala Podlaska, Lubelskie
Local Institution - 0414, Olsztyn, Warminsko-Mazurskie
Local Institution - 0120, Gdansk, Not set
Wojewodzkie Centrum Onkologii, Gdansk, Not set
Local Institution - 0377, Krakow, Not set
Local Institution - 0252, Krakow, Not set
Local Institution - 0373, Krakow, Not set
Instytut MSF Sp zoo, Lodz, Not set
Local Institution - 0118, Lublin, Not set
Local Institution - 0178, Poznan, Not set
Wojskowy Instytut Medyczny, Warsaw, Not set
Local Institution, Warsaw, Not set
Local Institution - 0328, Warszawa, Not set
Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warszawa, Not set
Local Institution - 0184, Lisboa, Not set
Local Institution - 0177, Lisbon, Not set
Local Institution - 0142, Porto, Not set
FDI Clinical Research, San Juan, Not set
Onco Clinic Consult SA, Craiova, Dolj
Local Institution - 0310, Bucharest, Sector 2
Institutul Oncologic Bucuresti IOB, Bucharest, Not set
Local Institution - 0127, Cluj Napoca, Not set
Institutul Oncologic Prof. Dr. I. Chiricuta, Cluj Napoca, Not set
Local Institution - 0189, Cluj-Napoca, Not set
Centrul de Oncologie Sf Nectarie, Craiova, Not set
Local Institution - 0133, Oradea, Not set
Sc Sigmedical Srl, Suceava, Not set
Local Institution - 0257, Krasnodar, Krasnodar Region
Local Institution - 0256, Krasnoyarsk, Not set
N.N. Blokhin National Medical Research Center of Oncology, Moscow, Not set
VitaMed LLC, Moscow, Not set
Local Institution - 0047, San Sebastian, Guipuzcoa
Local Institution - 0287, Majadahonda, Madrid
Clinica Universidad de Navarra, Pamplona, Navarra
Local Institution - 0122, A Coruna, Not set
Local Institution - 0382, A Coruna, Not set
Local Institution - 0173, Alicante, Not set
Catalan Institute of Badalona Hospital Germans Trias i Pujol ICO, Badalona, Not set
Local Institution - 0384, Barcelona, Not set
Hospital Universitari Vall d Hebron, Barcelona, Not set
Hospital Clinic de Barcelona, Barcelona, Not set
Local Institution - 0026, Barcelona, Not set
Local Institution - 0225, Barcelona, Not set
Local Institution, Barcelona, Not set
Local Institution - 0146, Burgos, Not set
Local Institution - 0144, Granada, Not set
Local Institution - 0273, Madrid, Not set
Local Institution - 0357, Madrid, Not set
Clinica Universidad de Navarra Madrid, Madrid, Not set
Local Institution - 0008, Madrid, Not set
Local Institution, Madrid, Not set
Local Institution - 0027, Madrid, Not set
Hospital Universitario Fundacion Jimenez Diaz, Madrid, Not set
Hospital Universitario 12 de Octubre, Madrid, Not set
Hospital Universitario La Paz, Madrid, Not set
Local Institution, Madrid, Not set
Hospital Universitario HM Sanchinarro, Madrid, Not set
Hospital Regional Universitario Carlos Haya, Malaga, Not set
Local Institution, Santa Cruz de Tenerife, Not set
Local Institution - 0352, Santander, Not set
Local Institution - 0274, Sevilla, Not set
Local Institution - 0294, Sevilla, Not set
Hospital General Universitario de Valencia, Valencia, Not set
Hospital Universitario y Politecnico de La Fe, Valencia, Not set
Local Institution, Goteborg, Not set
Local Institution - 0036, Malmoe, Not set
Local Institution, Umea, Not set
Local Institution - 0119, Basel, Not set
Local Institution - 0403, St.Gallen, Not set
UniversitaetsSpital Zuerich - Dermatology, Zurich, Not set
Local Institution - 0388, Taichung, Not set
Local Institution - 0197, Tainan, Not set
Local Institution - 0412, Taipei, Not set
Taipei Veterans General Hospital TPVGH, Taipei, Not set
Local Institution - 0330, Ankara, Not set
North Middlesex University Hospital, London, Greater London
University College Hospital, London, Greater London
Royal Marsden Hospital Sutton, London, Greater London
Local Institution - 0086, London, Greater London
The Christie Hospital, Manchester, Greater Manchester
Local Institution - 0195, Southampton, Hampshire
Local Institution - 0231, Maidstone, Kent
East & North Hertfordshire NHS Trust, Northwood, Middlesex
Local Institution - 0299, Edinburgh, Scotland
Conditions: Cancer
Pembrolizumab and Brentuximab Vedotin vs GDP and Stem Cell Transplant for Relapsed/Refractory Hodgkin Lymphoma
Recruiting
This study is being done to determine if two new drugs can shrink or eliminate classical Hodgkins lymphoma.
This study is being done to determine if two new drugs can shrink or eliminate classical Hodgkins lymphoma. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/14/2025
Locations: Concord Repatriation General Hospital, Concord, New South Wales +17 locations
Concord Repatriation General Hospital, Concord, New South Wales
Shoalhaven Cancer Care Centre, Nowra, New South Wales
Wollongong Hospital, Wollongong, New South Wales
Royal Adelaide Hospital, Adelaide, South Australia
Austin Hospital, Heidelberg, Victoria
Sir Charles Gairdner Hospital, Perth, Western Australia
Arthur J.E. Child Comprehensive Cancer Centre, Calgary, Alberta
BCCA - Vancouver, Vancouver, British Columbia
Dr. H. Bliss Murphy Cancer Centre, St. John's, Newfoundland and Labrador
QEII Health Sciences Centre, Halifax, Nova Scotia
Juravinski Cancer Centre at Hamilton Health Sciences, Hamilton, Ontario
London Health Sciences Centre Research Inc., London, Ontario
Ottawa Hospital Research Institute, Ottawa, Ontario
University Health Network, Toronto, Ontario
The Jewish General Hospital, Montreal, Quebec
The Research Institute of the McGill University, Montreal, Quebec
CIUSSS de l'Estrie - Centre hospitalier, Sherbrooke, Quebec
Allan Blair Cancer Centre, Regina, Saskatchewan
Conditions: Hodgkin Lymphoma
A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors
Recruiting
This clinical trial is studying advanced solid tumors. Solid tumors are cancers that start in a part of your body like your lungs or liver instead of your blood. Once tumors have grown bigger in one place but haven't spread, they're called locally advanced. If your cancer has spread to other parts of your body, it's called metastatic. When a cancer has gotten so big it can't easily be removed or has spread to other parts of the body, it is called unresectable. These types of cancer are harder to... Read More
This clinical trial is studying advanced solid tumors. Solid tumors are cancers that start in a part of your body like your lungs or liver instead of your blood. Once tumors have grown bigger in one place but haven't spread, they're called locally advanced. If your cancer has spread to other parts of your body, it's called metastatic. When a cancer has gotten so big it can't easily be removed or has spread to other parts of the body, it is called unresectable. These types of cancer are harder to treat.
Participants in this study must have cancer that has come back or did not get better with treatment. Participants must have a solid tumor cancer that can't be treated with standard of care drugs.
This clinical trial uses an experimental drug called PF-08046050. PF-08046050 is a type of antibody-drug conjugate or ADC. ADCs are designed to stick to cancer cells and kill them. They may also stick to some normal cells.
This study will test the safety of PF-08046050 in participants with solid tumors that are hard to treat or have spread throughout the body.
This study has 5 different study parts. Part A and Part B of the study will find out how much PF-08046050 should be given to participants. Part C will use the information from Parts A and B to see if PF-08046050 is safe and if it works to treat certain solid tumor cancers. Part D of the study, together with information from Parts A and B, will find out how much PF-08046050 should be given to participants in combination with bevacizumab. Part E will use the information from Parts A, B, and D to see if PF-08046050 is safe in combination with bevacizumab and if it works to treat a certain solid tumor. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/14/2025
Locations: Mayo Clinic Hospital, Phoenix, Arizona +26 locations
Mayo Clinic Hospital, Phoenix, Arizona
City of Hope, Duarte, California
University of Colorado Hospital - Anschutz Cancer Pavilion (ACP), Aurora, Colorado
University of Colorado Hospital/University of Colorado, Aurora, Colorado
Florida Cancer Specialists, Orlando, Florida
Sarah Cannon Research Institute at Florida Cancer Specialists, Orlando, Florida
Sidney Kimmel Comprehensive Cancer at Johns Hopkins, Baltimore, Maryland
Beth Israel Deaconess Medical Center, Boston, Massachusetts
START Midwest, Grand Rapids, Michigan
Mayo Clinic Cancer Center, Rochester, Minnesota
Sarah Cannon Research Institute - Pharmacy, Nashville, Tennessee
SCRI Oncology Partners, Nashville, Tennessee
The University of Texas MD Anderson Cancer Center, Houston, Texas
South Texas Accelerated Research Therapeutics, LLC, San Antonio, Texas
South Texas Accelerated Research Therapeutics Mountain Region, West Valley City, Utah
The Ottawa Hospital, Ottawa, Ontario
University Health Network, Princess Margaret Hospital, Toronto, Ontario
McGill University Health Centre, Montreal, Quebec
Institut Gustave Roussy, Villejuif Cedex, Paris
Gustave Roussy, Villejuif, Not set
Netherlands Cancer Institute, Amsterdam, Not set
Institut Catala d'Oncologia - Hospital Duran i Reynals (ICO L'Hospitalet), L'Hospitalet de Llobregat, Catalunya [cataluña]
START Madrid-CIOCC_Hospital HM Sanchinarro, Madrid, Not set
Karolinska University Hospital, Solna, Not set
ApoEx NKS, Stockholm, Not set
The University of Edinburgh, Edinburgh, Not set
Sarah Cannon Research Institute UK, London, Not set
Conditions: Colorectal Neoplasms, Carcinoma, Non-Small-Cell Lung, Stomach Neoplasms, Pancreatic Ductal Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma, Small Cell Lung Carcinoma
A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
Recruiting
The purpose of this study is to compare sacituzumab tirumotecan as a single agent, and in combination with pembrolizumab, versus Treatment of Physician's Choice (TPC) in participants with hormone receptor positive/human epidermal growth factor receptor-2 negative (HR+/HER2-) unresectable locally advanced, or metastatic, breast cancer.
The primary hypotheses are that sacituzumab tirumotecan as a single agent and sacituzumab tirumotecan plus pembrolizumab are superior to TPC with respect to progr... Read More
The purpose of this study is to compare sacituzumab tirumotecan as a single agent, and in combination with pembrolizumab, versus Treatment of Physician's Choice (TPC) in participants with hormone receptor positive/human epidermal growth factor receptor-2 negative (HR+/HER2-) unresectable locally advanced, or metastatic, breast cancer.
The primary hypotheses are that sacituzumab tirumotecan as a single agent and sacituzumab tirumotecan plus pembrolizumab are superior to TPC with respect to progression-free survival (PFS) per Response Evaluation Criteria in Solid Tumors version 1.1 (RECIST 1.1) by blinded independent central review (BICR) in all participants. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/14/2025
Locations: Ironwood Cancer & Research Centers ( Site 0066), Chandler, Arizona +241 locations
Ironwood Cancer & Research Centers ( Site 0066), Chandler, Arizona
Banner MD Anderson Cancer Center-Oncology ( Site 0004), Gilbert, Arizona
Providence Medical Foundation-Oncology ( Site 0020), Fullerton, California
Moores Cancer Center ( Site 0059), La Jolla, California
Cancer and Blood Specialty Clinic ( Site 0001), Los Alamitos, California
University of Colorado Anschutz Medical Campus ( Site 0061), Aurora, Colorado
UCHealth Cherry Creek Medical Center ( Site 0094), Denver, Colorado
University of Colorado Health - Highlands Ranch Hospital ( Site 0095), Highlands Ranch, Colorado
Yale Cancer Center ( Site 0060), New Haven, Connecticut
Stamford Hospital ( Site 0049), Stamford, Connecticut
AdventHealth Altamonte Springs ( Site 0021), Altamonte Springs, Florida
University of Florida College of Medicine ( Site 0063), Gainesville, Florida
Orlando Health Cancer Institute ( Site 0011), Orlando, Florida
Archbold Memorial Hospital-Lewis Hall Singletary Oncology Center ( Site 0032), Thomasville, Georgia
University of Chicago Medical Center ( Site 0067), Chicago, Illinois
Saint Elizabeth Medical Center Edgewood-Cancer Care Center ( Site 0053), Edgewood, Kentucky
Mary Bird Perkins Cancer Center-Breast & GYN Pavilion ( Site 0042), Baton Rouge, Louisiana
Greenebaum Comprehensive Cancer Center ( Site 0036), Baltimore, Maryland
Mercy Medical Center - Baltimore-Medical Oncology and Hematology ( Site 0028), Baltimore, Maryland
Holy Cross Hospital ( Site 0073), Silver Spring, Maryland
Dana-Farber Cancer Institute-Breast Oncology Center ( Site 0037), Boston, Massachusetts
Henry Ford Health ( Site 0002), Detroit, Michigan
Saint Luke's Cancer Institute ( Site 0027), Kansas City, Missouri
Washington University School of Medicine ( Site 0076), Saint Louis, Missouri
Laura and Isaac Perlmutter Cancer Center-Hematology and Oncology ( Site 0068), New York, New York
Hematology Oncology Associates of Rockland ( Site 0054), Nyack, New York
Stony Brook University-Cancer Center ( Site 0034), Stony Brook, New York
Levine Cancer Institute ( Site 0014), Charlotte, North Carolina
Zangmeister Cancer Center ( Site 7000), Columbus, Ohio
Providence Portland Medical Center ( Site 0044), Portland, Oregon
Providence St. Vincent Medical Center ( Site 0081), Portland, Oregon
Thomas Jefferson University - Clinical Research Institute ( Site 0056), Philadelphia, Pennsylvania
Texas Oncology-Dallas Presbyterian Hospital ( Site 8000), Dallas, Texas
The Center for Cancer and Blood Disorders ( Site 0041), Fort Worth, Texas
Texas Oncology - San Antonio ( Site 8002), San Antonio, Texas
The University of Texas Health Science Center at Tyler dba UT Health East Texas HOPE Cancer Center ( Site 0057), Tyler, Texas
Inova Schar Cancer Institute ( Site 0025), Fairfax, Virginia
Bon Secours St. Francis Medical Center-Oncology Research ( Site 0015), Midlothian, Virginia
VCU Health Adult Outpatient Pavillion ( Site 0070), Richmond, Virginia
Oncology and Hematology Associates of Southwest Virginia (BRCC) ( Site 8001), Roanoke, Virginia
University Hospital and UW Health Clinics-Carbone Cancer Center ( Site 0040), Madison, Wisconsin
Instituto Alexander Fleming-Alexander Fleming ( Site 0382), Ciudad Autónoma de Buenos Aires, Caba
Fundacion Estudios Clinicos-Oncology ( Site 0384), Rosario, Santa Fe
Hospital Aleman-Oncology ( Site 0386), Buenos Aires, Not set
Centro de Educación Médica e Investigaciones clínicas "Dr. Norberto Quirno" (CEMIC) ( Site 0383), Buenos Aires, Not set
Hospital Italiano de Córdoba ( Site 0385), Cordoba, Not set
Fundación CORI para la Investigación y Prevención del Cáncer ( Site 0387), La Rioja, Not set
Macquarie University-MQ Health Clinical Trials Unit ( Site 2002), Macquarie University, New South Wales
Westmead Hospital ( Site 2000), Westmead, New South Wales
Frankston Hospital-Oncology and Haematology ( Site 2003), Frankston, Victoria
Fiona Stanley Hospital-Medical Oncology ( Site 2004), Murdoch, Western Australia
Institut Jules Bordet-Medicine Oncology ( Site 1104), Anderlecht, Bruxelles-Capitale, Region De
Cliniques universitaires Saint-Luc-Medical Oncology ( Site 1103), Brussels, Bruxelles-Capitale, Region De
Jessa Ziekenhuis-Limburgs Oncologisch Centrum ( Site 1105), Hasselt, Limburg
AZ Maria Middelares-IKG ( Site 1106), Gent, Oost-Vlaanderen
Université Catholique de Louvain-Namur - Centre Hospitalier -Oncology ( Site 1107), Namur, Not set
Oncoclínica Oncologistas Associados-Clinical Research ( Site 0407), Teresina, Piaui
Hospital Moinhos de Vento ( Site 0403), Porto Alegre, Rio Grande Do Sul
Hospital do Câncer Mãe de Deus ( Site 0404), Porto Alegre, Rio Grande Do Sul
Instituto de Oncologia Saint Gallen ( Site 0412), Santa Cruz do Sul, Rio Grande Do Sul
Instituto do Câncer Brasil - Unidade Taubaté ( Site 0408), Taubaté, Sao Paulo
IBCC - Núcleo de Pesquisa e Ensino ( Site 0401), Sao Paulo, Not set
BC Cancer Surrey ( Site 0315), Surrey, British Columbia
Southlake Regional Health Centre ( Site 0311), Newmarket, Ontario
Princess Margaret Cancer Centre ( Site 0310), Toronto, Ontario
CIUSSS de l'Est-de-l'Île-de-Montréal ( Site 0301), Montreal, Quebec
Jewish General Hospital ( Site 0303), Montreal, Quebec
Centre intégré de santé et de services sociaux du Bas Saint-Laurent- Hôpital régional de Rimouski ( Site 0308), Rimouski, Quebec
CHU de Quebec Universite Laval - Hopital du Saint-Sacrement ( Site 0302), Quebec, Not set
Oncovida ( Site 0453), Santiago., Region M. De Santiago
Clínica RedSalud Vitacura ( Site 0455), Santiago., Region M. De Santiago
FALP-UIDO ( Site 0451), Santiago, Region M. De Santiago
Pontificia Universidad Catolica de Chile ( Site 0454), Santiago, Region M. De Santiago
Bradfordhill ( Site 0452), Santiago, Region M. De Santiago
Bradford Hill Norte ( Site 0456), Antofagasta, Not set
Fundacion Colombiana de Cancerología Clinica Vida ( Site 0506), Medellín, Antioquia
Sociedad De Oncología y Hematología Del Cesar SAS-Oncology ( Site 0501), Valledupar, Cesar
IMAT S.A.S ( Site 0502), Monteria., Cordoba
FUNDACION CTIC CENTRO DE TRATAMIENTO E INVESTIGACION SOBRE CANCER LUIS CARLOS SARMIENTO ANGULO ( Site 0507), Bogota, Distrito Capital De Bogota
Fundación Valle del Lili ( Site 0508), Cali, Valle Del Cauca
CIMCA ( Site 0551), San José, San Jose
Hospital Metropolitano - Sede Lindora ( Site 0550), Santa Ana, San Jose
ICIMED ( Site 0552), San Jose, Not set
Nemocnice Ceske Budejovice-Onkologicke oddeleni ( Site 1138), Ceske Budejovice, Jihocesky Kraj
Fakultni nemocnice Ostrava-Klinika onkologicka ( Site 1134), Ostrava-Poruba, Moravskoslezsky Kraj
Fakultni nemocnice Olomouc-Onkologicka klinika ( Site 1132), Olomouc, Olomoucky Kraj
Fakultni nemocnice v Motole-Onkologicka klinika 2. LF UK a FN Motol ( Site 1136), Praha, Praha 5
Fakultni nemocnice Kralovske Vinohrady-Onkologická klinika ( Site 1135), Praha 10, Not set
Rigshospitalet ( Site 1180), Copenhagen, Hovedstaden
Nordsjællands Hospital - Hillerød ( Site 1184), Hillerod, Hovedstaden
Næstved Sygehus ( Site 1182), Naestved, Sjaelland
Odense Universitetshospital ( Site 1181), Odense C, Syddanmark
Vejle Sygehus ( Site 1183), Vejle, Syddanmark
Centre François Baclesse ( Site 1250), Caen, Calvados
Centre de Cancérologie du Grand Montpellier ( Site 1244), Montpellier, Languedoc-Roussillon
Hôpital privé du Confluent SAS-Service d'oncologie médicale ( Site 1242), Nantes, Loire-Atlantique
Pitie Salpetriere University Hospital ( Site 1249), Paris, Orne
Hopital Prive Jean Mermoz-Oncology ( Site 1246), Lyon, Rhone-Alpes
Centre Hospitalier Universitaire de Poitiers-Pôle régional de cancérologie ( Site 1243), Poitiers, Vienne
Institut Curie-Oncology medical Department ( Site 1240), Paris, Not set
SRH Wald-Klinikum Gera-Zentrum für klinische Studien ( Site 1315), Gera, Thuringen
Helios Klinikum Berlin-Buch-Klinik für Gynäkologie und Geburtshilfe ( Site 1314), Berlin, Not set
Errikos Dunant Hospital Center ( Site 1348), Athens, Attiki
Aretaieio Hospital Oncology Unit ( Site 1345), Athens, Attiki
Hygeia Hospital ( Site 1346), Marousi, Attiki
University General Hospital of Larissa ( Site 1343), Larissa, Thessalia
Agios Loukas Clinic ( Site 1347), Thessaloniki, Not set
European Interbalkan Medical Center ( Site 1341), Thessaloniki, Not set
Queen Mary Hospital ( Site 2040), Hksar, Not set
Prince of Wales Hospital ( Site 2041), Shatin, Not set
Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ-Onkoterápiás Klinika ( Site 1379), Szeged, Csongrad
Somogy Vármegyei Kaposi Mór Oktató Kórház-Oncology center ( Site 1371), Kaposvár, Somogy
Zala Vármegyei Szent Rafael Kórház-Onkológiai osztály ( Site 1372), Zalaegerszeg, Zala
Semmelweis Egyetem-Belgyógyászati és Onkológiai Klinika ( Site 1381), Budapest, Not set
Budapesti Uzsoki Utcai Kórház-Onkoradiológiai Osztály ( Site 1373), Budapest, Not set
Debreceni Egyetem Klinikai Kozpont-Onkológiai Klinika ( Site 1375), Debrecen, Not set
All India Institute of Medical Sciences ( Site 2051), New Delhi, Delhi
Rajiv Gandhi Cancer Institute And Research Centre-Department of Clinical Research ( Site 2052), New Delhi, Delhi
Tata Memorial Hospital-Medical Oncology ( Site 2053), Mumbai, Maharashtra
Kokilaben Dhirubhai Ambani Hospital & Medical Research Institute-Centre for cancer ( Site 2056), Mumbai, Maharashtra
Bon Secours Cork Hospital ( Site 1422), Cork, Not set
St. Vincent's University Hospital-Medical Oncology Research Department ( Site 1420), Dublin, Not set
Mater Misericordiae University Hospital-Clinical Trials Research Unit ( Site 1423), Dublin, Not set
Rambam Health Care Campus-Oncology Division ( Site 1452), Haifa, Not set
Hadassah Medical Center ( Site 1451), Jerusalem, Not set
Rabin Medical Center ( Site 1453), Petah Tikva, Not set
Sheba Medical Center ( Site 1450), Ramat Gan, Not set
IRCCS - Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori" ( Site 1480), Meldola, Forli-Cesena
CRO-IRCCS ( Site 1478), Aviano, Friuli-Venezia Giulia
Istituto Europeo di Oncologia IRCCS-Divisione di Senologia Medica ( Site 1475), Milano, Lombardia
Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Oncologia Medica 1 ( Site 1472), Milan, Lombardia
Istituto Clinico Humanitas ( Site 1476), Rozzano, Milano
IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico di Sant'Orsola ( Site 1474), Bologna, Not set
Ospedale San Martino ( Site 1479), Genova, Not set
Ospedale San Raffaele-Oncologia Medica ( Site 1471), Milano, Not set
Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore ( Site 1477), Roma, Not set
Nagoya City University Hospital ( Site 2474), Nagoya, Aichi
Hokkaido University Hospital ( Site 2460), Sapporo, Hokkaido
Tokai University Hospital ( Site 2473), Isehara, Kanagawa
St. Marianna University Hospital ( Site 2465), Kawasaki, Kanagawa
Kitasato University Hospital ( Site 2471), Sagamihara, Kanagawa
Kanagawa Cancer Center ( Site 2472), Yokohama, Kanagawa
Mie University Hospital ( Site 2483), Tsu, Mie
Tohoku University Hospital ( Site 2482), Sendai, Miyagi
The University of Osaka Hospital ( Site 2476), Suita, Osaka
Saitama Medical University International Medical Center ( Site 2462), Hidaka, Saitama
Juntendo University Hospital ( Site 2468), Bunkyo, Tokyo
Cancer Institute Hospital of JFCR ( Site 2464), Koto, Tokyo
Showa Medical University Hospital ( Site 2466), Shinagawa, Tokyo
Tokyo Medical University Hospital ( Site 2467), Shinjuku, Tokyo
National Center for Global Health and Medicine ( Site 2469), Shinjuku, Tokyo
Fukushima Medical University Hospital ( Site 2461), Fukushima, Not set
Gifu University Hospital ( Site 2486), Gifu, Not set
Hiroshima City Hiroshima Citizens Hospital ( Site 2478), Hiroshima, Not set
Social medical corporation Hakuaikai Sagara Hospital ( Site 2481), Kagoshima, Not set
Kumamoto University Hospital ( Site 2480), Kumamoto, Not set
Kyoto University Hospital ( Site 2475), Kyoto, Not set
Okayama University Hospital ( Site 2485), Okayama, Not set
Osaka International Cancer Institute ( Site 2477), Osaka, Not set
Seoul National University Hospital-Internal Medicine ( Site 2353), Seoul, Not set
Severance Hospital, Yonsei University Health System-Medical oncology ( Site 2350), Seoul, Not set
Asan Medical Center-Department of Oncology ( Site 2352), Seoul, Not set
Samsung Medical Center-Division of Hematology/Oncology ( Site 2351), Seoul, Not set
Hospital Sultan Ismail ( Site 2153), Johor Bahru, Johor
Sarawak General Hospital ( Site 2154), Kuching, Sarawak
Pantai Hospital Kuala Lumpur ( Site 2151), Kuala Lumpur, Not set
Health Pharma Professional Research S.A. de C.V: ( Site 0598), Ciudad de México, Distrito Federal
Grupo Médico ASSET-Clinical Research ( Site 0596), Mexico City, Distrito Federal
CIO - Centro de Inmuno-Oncología de Occidente ( Site 0592), Guadalajara, Jalisco
Hospital Universitario "Dr. Jose Eleuterio Gonzalez"-Servicio de Oncología ( Site 0590), Monterrey, Nuevo Leon
CENTRO MEDICO ZAMBRANO HELLION-Centro de Cáncer de Mama ( Site 0595), San Pedro Garza Garcia, Nuevo Leon
Ziekenhuis Rijnstate-Rijnstate Centrum Oncologisch Onderzoek ( Site 1524), Arnhem, Gelderland
Maastricht UMC+-Medical Oncology ( Site 1522), Maastricht, Limburg
Amphia Ziekenhuis, locatie Breda Molengracht-oncologie ( Site 1523), Breda, Noord-Brabant
Catharina Ziekenhuis ( Site 1526), Eindhoven, Noord-Brabant
Nederlands Kanker Instituut - Antoni van Leeuwenhoek (NKI-AVL)-medical oncology ( Site 1520), Amsterdam, Noord-Holland
Isala, locatie Zwolle ( Site 1525), Zwolle, Overijssel
Meander Medisch Centrum ( Site 1521), Amersfoort, Utrecht
Auckland City Hospital ( Site 2031), Auckland, Not set
Clinica Vallesur - AUNA ( Site 0652), Arequipa, Ariqipa
Hospital Militar Central Luis Arias Schereiber ( Site 0651), Jesús María, Lima
Oncosalud ( Site 0650), Lima, Muni Metro De Lima
IPOR Instituto Peruano de Oncología & Radioterapia ( Site 0653), Lima, Not set
Centrum Onkologii im. Prof. Franciszka Lukaszczyka-Ambulatorium Chemioterapii ( Site 1582), Bydgoszcz, Kujawsko-pomorskie
Mazowiecki Szpital Wojewódzki w Siedlcach-Siedleckie Centrum Onkologii ( Site 1584), Siedlce, Mazowieckie
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Klinika Nowotworów Piersi i Chirurgii ( Site 1580), Warszawa, Mazowieckie
Mazowiecki Szpital Onkologiczny ( Site 1581), Wieliszew, Mazowieckie
Mrukmed-Mrukmed ( Site 1592), Rzeszow, Podkarpackie
Bialostockie Centrum Onkologii ( Site 1585), Bialystok, Podlaskie
Szpitale Pomorskie Sp. z o. o.-Oddział Onkologii Klinicznej ( Site 1593), Gdynia, Pomorskie
Narodowy Instytut Onkologii - Oddzial w Gliwicach-Centrum Diagnostyki i Leczenia Chorob Piersi ( Site 1590), Gliwice, Slaskie
Swietokrzyskie Centrum Onkologii, Samodzielny Publiczny Zakl-Klinika Onkologii Klinicznej, Dzial Ch ( Site 1595), Kielce, Swietokrzyskie
Szpital Wojewódzki im. Mikoaja Kopernika w Koszalinie-Oddzial Dzienny Chemioterapii ( Site 1583), Koszalin, Zachodniopomorskie
Zachodniopomorskie Centrum Onkologii ( Site 1588), Szczecin, Zachodniopomorskie
Unidade Local de Saude Amadora/Sintra - Hospital Prof Dr Fernando Fonseca ( Site 1663), Lisbon, Lisboa
Unidade Local de Saude de Santa Maria - Hospital de Santa Maria ( Site 1661), Lisboa, Not set
Instituto Português de Oncologia do Porto Francisco Gentil, EPE ( Site 1662), Porto, Not set
Puerto Rico Medical Research Center LLC ( Site 0675), Hato Rey, Not set
UPR Comprehensive Cancer Center-Comprehensive Cancer Center Hospital ( Site 0677), San Juan, Not set
Spitalul Clinic Filantropia ( Site 1703), București, Bucuresti
SC Radiotherapy Center Cluj SRL-Oncologie Medicala ( Site 1702), Florești, Cluj
Centrul Medical Neolife- Baneasa ( Site 1704), Bucuresti, Not set
Institutul Oncologic Cluj ( Site 1701), Cluj, Not set
National University Hospital ( Site 2250), Singapore, Central Singapore
Mount Alvernia ICON Cancer Center ( Site 2251), Singapore, North East
CANCERCARE LANGENHOVEN DRIVE ONCOLOGY CENTRE ( Site 2905), Port Elizabeth, Eastern Cape
Curo Oncology ( Site 2908), Pretoria, Gauteng
Sandton Oncology Medical Group (Pty) Ltd ( Site 2911), Sandton, Gauteng
Cancercare Rondebosch Oncology-Clinical trials ( Site 2904), Rondebosch, Western Cape
HOSPITAL UNIVERSITARIO QUIRONSALUD MADRID ( Site 1758), Pozuelo de Alarcon, Madrid
HOSPITAL CLINICO DE VALENCIA-Oncology ( Site 1752), Valencia, Valenciana, Comunitat
Hospital Universitari Vall d'Hebron-Oncology ( Site 1750), Barcelona, Not set
Hospital Universitario Reina Sofia-Oncologia Medica ( Site 1754), Cordoba, Not set
Hospital Beata María Ana-oncology ( Site 1755), Madrid, Not set
HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑON-ONCOLOGY ( Site 1756), Madrid, Not set
Hospital Universitario Virgen Macarena ( Site 1757), Sevilla, Not set
Karolinska Universitetssjukhuset Solna ( Site 1801), Stockholm, Stockholms Lan
Akademiska sjukhuset ( Site 1802), Uppsala, Uppsala Lan
Södra Älvsborgs Sjukhus Borås ( Site 1803), Borås, Vastra Gotalands Lan
University Hospital Basel-Gynecology & Gynecologic Oncology ( Site 1844), Basel, Basel-Stadt
Spital Thun ( Site 1840), Thun, Berne
Brust-Zentrum ( Site 1841), Zürich, Zurich
Changhua Christian Hospital ( Site 2410), Changhua, Not set
Chang Gung Memorial Hospital at Kaohsiung-Oncology and Hematology ( Site 2413), Kaohsiung, Not set
National Cheng Kung University Hospital-Surgery ( Site 2411), Tainan, Not set
National Taiwan University Hospital-Oncology ( Site 2415), Taipei, Not set
Mackay Memorial Hospital ( Site 2412), Taipei, Not set
Chang Gung Medical Foundation-Linkou Branch-General Surgery ( Site 2414), Taoyuan, Not set
Dr. Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastırma Hastanesi ( Site 1878), Yenimahalle, Ankara
Medipol Mega Universite Hastanesi-oncology ( Site 1875), Stanbul, Istanbul
Adana Medical Park Seyhan Hastanesi-Medikal Onkoloji ( Site 1876), Adana, Not set
Hacettepe Universite Hastaneleri-oncology hospital ( Site 1870), Ankara, Not set
Memorial Ankara Hastanesi-Medical Oncology ( Site 1874), Ankara, Not set
Ankara Bilkent Şehir Hastanesi-Medical Oncology ( Site 1871), Ankara, Not set
TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 1872), Istanbul, Not set
Samsun Medical Park Hastanesi-medical oncology ( Site 1873), Samsun, Not set
North West Cancer Centre ( Site 1944), Londonderry, Derry And Strabane
The Royal Cornwall Hospital ( Site 1943), Truro, England
St Bartholomew's Hospital-Centre for Experimental Cancer Medicine ( Site 1940), London, London, City Of
University College London Hospital-Cancer Clinical Trials Unit ( Site 1942), London, London, City Of
Blackpool Victoria Hospital ( Site 1941), Blackpool, Not set
City Hospital, Nottingham University Hospitals NHS Trust ( Site 1945), Nottingham, Not set
Conditions: Breast Neoplasms
The ReTAVI Prospective Observational Registry
Recruiting
Patients with severe aortic stenosis (sAS) treated with transcatheter aortic valve implantation (TAVI) (increasingly younger \& lower risk pts) are experiencing SVD of the index THV and thus developing an indication for a redo-TAVI procedure.
The evidence on redo-TAVI (where a transcatheter heart valve \[THV\] is implanted into another THV) is limited, with initial data showing acceptable safety as well efficacy in highly selected and limited populations.
Aim is to evaluate short- and long-ter... Read More
Patients with severe aortic stenosis (sAS) treated with transcatheter aortic valve implantation (TAVI) (increasingly younger \& lower risk pts) are experiencing SVD of the index THV and thus developing an indication for a redo-TAVI procedure.
The evidence on redo-TAVI (where a transcatheter heart valve \[THV\] is implanted into another THV) is limited, with initial data showing acceptable safety as well efficacy in highly selected and limited populations.
Aim is to evaluate short- and long-term data on patients undergoing transcatheter redo-TAVI procedures with THVs for failure of a previously implanted THV and to determine VARC-3 defined efficacy and safety at 30 days and functional outcome at 1 year, 3 years and 5 years. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/14/2025
Locations: LKH-University Hospital and Medical University of Graz, Graz, Not set +61 locations
LKH-University Hospital and Medical University of Graz, Graz, Not set
Kepler University Clinic Linz, Linz, Not set
University Hospital St. Pölten, St. Pölten, Not set
Medical University of Vienna, Vienna, Not set
McGill University Health Centre, Montréal, Not set
Institut Universitaire de Cardiologie et de Pneumologie, Québec, Not set
St. Paul's Hospital, Vancouver, Vancouver, Not set
Centre Hospitalier Universitaire de Bordeaux, Bordeaux, Not set
Centre Hospitalier Universitaire de Clermont-Ferrand, Clermont-Ferrand, Not set
Centre Hospitalier Universitaire de Lille, Lille, Not set
Hospices Civils de Lyon, Lyon, Not set
Hôpitaux Universitaires de Marseille Timone, Marseille, Not set
Jacques Cartier Private Hospital, Massy, Massy, Not set
Centre Hospitalier Universitaire de Nantes, Nantes, Not set
Hôpital Européen Georges-Pompidou, Paris, Not set
Hôpital Bichat-Claude-Bernard, Paris, Not set
Centre hospitalier universitaire de Rennes, Rennes, Not set
Centre Hospitalier Universitaire de Rouen, Roubaix, Not set
Clinique de la Porte de Paris (CCN), Saint-Denis, Not set
Centre Hospitalier Universitaire de Toulouse, Toulouse, Not set
University Heart Center Freiburg Bad Krozingen, Bad Krozingen, Not set
Kerckhoff-Klinik GmbH, UKGM GmbH, Bad Nauheim, Not set
Heart and Diabetes Center North Rhine-Westphalia, Bad Oeynhausen, Not set
German Heart Center of Charité Berlin, Berlin, Not set
BG University Hospital Bergmannsheil gGmbH, Bochum, Not set
University Hospital of Duesseldorf, Duesseldorf, Not set
Elisabeth Hospital, Essen, Essen, Not set
German Heart Centre Munich, Munich, Not set
Robert-Bosch-Hospital, Stuttgart, Stuttgart, Not set
University Hospital Ulm, Ulm, Not set
Tel Aviv Medical Center, Tel Aviv, Not set
AOU Ospedali Riuniti Ancona, Umberto I, G. M. Lancisi, G. Salesi, Ancona, Not set
IRCCS Azienda Ospedaliero Universitaria di Bologna, Bologna, Not set
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia, Brescia, Not set
Careggi Hospital, Florence, Not set
IRCCS Ospedale Galeazzi Sant'Ambrogio, Milan, Not set
Azienda Ospedale-Università Padova (AOUP), Padua, Not set
Azienda Ospedaliero-Universitaria Pisana, Pisa, Not set
Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Not set
Policlinici universitari | Sapienza Università di Roma, Roma, Not set
Università degli Studi di Trieste, Trieste, Not set
Ospedale San Bortolo di Vicenza, Vicenza, Not set
St. Antonius Ziekenhuis, Nieuwegein, Nieuwegein, Not set
Medical University of Bialystok, Bialystok, Not set
University Clinical Centre of Gdańsk, Gdańsk, Not set
Medical University of Silesia, Katowice, Not set
University Hospital of Kraków, Kraków, Not set
Medical University of Warsaw, Warsaw, Not set
Institute of Cardiology Warsaw, Warsaw, Not set
Wroclaw Medical University, Wrocław, Not set
Hospital de Santa Cruz, Carnaxide-Lisabon, Carnaxide, Not set
Centro Hospitalar Vila Nova de Gaia / Espinho, Vila Nova De Gaia, Not set
Hospital de la Santa Creu i Sant Pau, Barcelona, Not set
Hospital Clinic de Barcelona, Barcelona, Not set
Hospital University Germans Trias i Pujol, Barcelona, Not set
Hospital Universitario de León, León, Not set
Hospital Clinico Universitario San Carlos, Madrid, Not set
Hospital Universitario Central de Asturias, Oviedo, Not set
Hospital Álvaro Cunqueiro, Vigo, Vigo, Not set
University Hospital of Basel, Basel, Not set
Hôpitaux universitaires de Genève, Geneva, Not set
Centre hospitalier universitaire vaudois et Université de Lausanne, Lausanne, Not set
Conditions: Structural Valve Deterioration, Structural Valve Degeneration, Symptomatic Patients Who Have Had Transcatheter Heart Valve (THV) Failure, Prosthetic Valve Malfunction, Prosthesis Failure
Pooled Analysis of Single-arm Studies of Budesonide/Glycopyrronium/Formoterol (BGF) in Routine Care Setting
Recruiting
The CHOROS pooled analysis is a retrospective secondary data use analysis of integrated individual participant data from a series of planned and on-going primary prospective, non-interventional, multi-center studies sponsored by AstraZeneca and conducted in the pulmonary/primary care practitioner setting in multiple countries and may include data from the following countries: United Kingdom, Germany, Italy, Greece, Japan, Canada and Romania.
The CHOROS pooled analysis is a retrospective secondary data use analysis of integrated individual participant data from a series of planned and on-going primary prospective, non-interventional, multi-center studies sponsored by AstraZeneca and conducted in the pulmonary/primary care practitioner setting in multiple countries and may include data from the following countries: United Kingdom, Germany, Italy, Greece, Japan, Canada and Romania. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/14/2025
Locations: Research Site, Mississauga, Not set +6 locations
Research Site, Mississauga, Not set
Research Site, Hamburg, Not set
Research Site, Athens, Not set
Research Site, Milan, Not set
Research Site, Tokyo, Not set
Research Site, Bucharest, Not set
Research Site, London, Not set
Conditions: Pulmonary Disease, Chronic Obstructive
Bomedemstat vs Hydroxyurea for Essential Thrombocythemia (MK-3543-007)
Recruiting
The purpose of this study is to evaluate the efficacy and safety of bomedemstat compared with hydroxyurea in cytoreductive therapy naïve essential thrombocythemia (ET) participants for whom cytoreductive therapy is indicated. Its primary objective is to compare bomedemstat to hydroxyurea with respect to durable clinicohematologic response (DCHR). The primary hypothesis is that bomedemstat is superior to hydroxyurea with respect to DCHR.
The purpose of this study is to evaluate the efficacy and safety of bomedemstat compared with hydroxyurea in cytoreductive therapy naïve essential thrombocythemia (ET) participants for whom cytoreductive therapy is indicated. Its primary objective is to compare bomedemstat to hydroxyurea with respect to durable clinicohematologic response (DCHR). The primary hypothesis is that bomedemstat is superior to hydroxyurea with respect to DCHR. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/14/2025
Locations: Los Angeles Cancer Network ( Site 0025), Glendale, California +125 locations
Los Angeles Cancer Network ( Site 0025), Glendale, California
Stanford Cancer Center ( Site 0024), Palo Alto, California
Exempla Lutheran Medical Center ( Site 0014), Golden, Colorado
Parkview Research Center at Parkview Regional Medical Center ( Site 0006), Fort Wayne, Indiana
University of Michigan ( Site 0003), Ann Arbor, Michigan
Duke University Health System (DUHS) ( Site 0012), Durham, North Carolina
Oregon Health & Science University ( Site 0018), Portland, Oregon
University of Texas MD Anderson Cancer Center ( Site 0026), Houston, Texas
University of Texas Health Science Center at San Antonio ( Site 0021), San Antonio, Texas
University of Virginia ( Site 0020), Charlottesville, Virginia
VCU Health Adult Outpatient Pavillion ( Site 0008), Richmond, Virginia
Hospital Universitario Austral ( Site 0101), Pilar, Buenos Aires
Hospital Italiano de Buenos Aires ( Site 0102), ABB, Caba
C.I.C.E. 9 de Julio ( Site 0104), San Miguel de Tucumán, Tucuman
Clínica de Nefrología, Urología y Enfermedades Cardiovasculares ( Site 0105), Santa Fe, Not set
Westmead Hospital ( Site 0201), Westmead, New South Wales
Royal Adelaide Hospital-Haematology Clinical Trials Unit ( Site 0203), Adelaide, South Australia
Monash Health-Haematology Research ( Site 0202), Clayton, Victoria
Austin Health-Cancer Clinical Trials Centre ( Site 0206), Heidelberg, Victoria
Royal Perth Hospital-Haematology ( Site 0204), Perth, Western Australia
Ordensklinikum Linz GmbH Elisabethinen ( Site 0562), Linz, Oberosterreich
Centre Intégré de Santé et de Services Sociaux de la Montérégie-Centre ( Site 0037), Greenfield Park, Quebec
Biocenter ( Site 0149), Concepcion, Biobio
IC La Serena Research ( Site 0150), La Serena., Coquimbo
FALP-UIDO ( Site 0148), Santiago, Region M. De Santiago
Clínica Inmunocel ( Site 0147), Santiago, Region M. De Santiago
Clínica Alemana de Santiago ( Site 0143), Santiago, Region M. De Santiago
Bradfordhill-Clinical Area ( Site 0142), Santiago, Region M. De Santiago
Fundacion Colombiana de Cancerología Clinica Vida ( Site 0164), Medellín, Antioquia
IMAT S.A.S ( Site 0162), Monteria, Cordoba
Los Cobos Medical Center ( Site 0165), Bogota, Distrito Capital De Bogota
Rigshospitalet-Hematology - CTU ( Site 0321), Copenhagen, Hovedstaden
Aarhus Universitetshospital, Skejby-Blodsygdomme ( Site 0324), Aarhus, Midtjylland
Roskilde Sygehus-Department of Hematology ( Site 0323), Roskilde, Sjaelland
Odense Universitetshospital-Department of Hematology ( Site 0325), Odense C, Syddanmark
Centre Hospitalier Universitaire de Nice - Hôpital l'Archet-Hematology ( Site 0349), Nice, Alpes-Maritimes
CHU Bordeaux Haut-Leveque-service de mèdecine interne et maladies infectieuses ( Site 0346), Pessac, Aquitaine
Hôpital de la Conception ( Site 0351), Marseille, Bouches-du-Rhone
Institut Universitaire du Cancer Toulouse - Oncopole - CHU de TOULOUSE ( Site 0352), Toulouse, Haute-Garonne
Centre Hospitalier Universitaire de Limoges - Hôpital Dupuytren ( Site 0344), Limoges, Haute-Vienne
Centre Hospitalier Régional Universitaire de Tours - Hôpital-Hématologie et Thérapie Cellulaire ( Site 0342), Tours, Indre-et-Loire
Centre Hospitalier Universitaire de Nantes - L' Hopital l'hôtel-Dieu ( Site 0347), Nantes, Loire-Atlantique
centre hospitalier lyon sud ( Site 0343), Pierre-Bénite, Rhone
HENRI MONDOR HOSPITAL ( Site 0348), Creteil, Val-de-Marne
Hopital Saint-Louis ( Site 0341), Paris, Not set
VK&K Studien GbR ( Site 0370), Landshut, Bayern
Medizinische Hochschule Hannover ( Site 0371), Hannover, Niedersachsen
Universitätsklinikum Aachen ( Site 0367), Aachen, Nordrhein-Westfalen
Universitaetsklinikum Essen ( Site 0366), Essen, Nordrhein-Westfalen
Universitätsmedizin Johannes Gutenberg Universität Mainz-3. Medizinische Klinik und Poliklinik ( Site 0365), Mainz, Rheinland-Pfalz
Universitätsklinikum Halle ( Site 0361), Halle, Sachsen-Anhalt
Universitätsklinikum Jena-Klinik für Innere Medizin II, Abt. Hämatologie und Internistische Onkolog ( Site 0364), Jena, Thuringen
Charité Universitaetsmedizin Berlin - Campus Mitte ( Site 0369), Berlin, Not set
Queen Mary Hospital ( Site 0221), Hksar, Not set
Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ-Belgyógyászati Klinika ( Site 0407), Szeged, Csongrad
Petz Aladar Egyetemi Oktato Korhaz-Hematológia ( Site 0405), Gyor, Gyor-Moson-Sopron
Somogy Vármegyei Kaposi Mór Oktató Kórház-Haematológiai osztály ( Site 0406), Kaposvár, Somogy
Szabolcs-Szatmár-Bereg Megyei Kórházak és Egyetemi Oktatókór-Haematológia osztály ( Site 0404), Nyiregyhaza, Szabolcs-Szatmar-Bereg
Debreceni Egyetem Klinikai Kozpont-Belgyógyászati Klinika (Haematologia) ( Site 0402), Debrecen, Not set
Soroka Medical Center ( Site 0427), Be'er Sheva, Not set
Rambam Health Care Campus ( Site 0429), Haifa, Not set
Carmel Hospital ( Site 0426), Haifa, Not set
Hadassah Medical Center ( Site 0424), Jerusalem, Not set
Galilee Medical Center ( Site 0431), Nahariya, Not set
Rabin Medical Center ( Site 0425), Petah Tikva, Not set
Sheba Medical Center ( Site 0428), Ramat Gan, Not set
Sourasky Medical Center ( Site 0422), Tel Aviv, Not set
Yitzhak Shamir Medical Center. ( Site 0421), Zerifin, Not set
Azienda Ospedaliero-Universitaria SS. Antonio e Biagio e Cesare Arrigo ( Site 0443), Alessandria, Ancona
Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico ( Site 0447), Milano, Lombardia
Azienda Ospedaliera Universitaria Careggi ( Site 0441), Firenze, Toscana
IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico di Sant'Orsola ( Site 0446), Bologna, Not set
Fondazione IRCCS Policlinico San Matteo-Oncology ( Site 0444), Pavia, Not set
Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore ( Site 0445), Roma, Not set
Ospedale di Circolo e Fondazione Macchi Varese ( Site 0442), Varese, Not set
Fujita Health University Hospital ( Site 0613), Toyoake, Aichi
Ehime University Hospital ( Site 0612), Toon, Ehime
Hokkaido University Hospital ( Site 0601), Sapporo, Hokkaido
Kobe City Medical Center General Hospital ( Site 0603), Kobe, Hyogo
Kanazawa University Hospital ( Site 0614), Kanazawa, Ishikawa
Mie University Hospital ( Site 0615), Tsu, Mie
National Hospital Organization Sendai Medical Center ( Site 0617), Sendai, Miyagi
Kansai Medical University Hospital ( Site 0607), Hirakata, Osaka
Kindai University Hospital ( Site 0600), Osakasayama, Osaka
Juntendo University Hospital ( Site 0611), Bunkyo-ku, Tokyo
University of Yamanashi Hospital ( Site 0606), Chuo, Yamanashi
Kyushu University Hospital ( Site 0605), Fukuoka, Not set
Fukushima Medical University Hospital ( Site 0616), Fukushima, Not set
University of Miyazaki Hospital ( Site 0609), Miyazaki, Not set
Okayama University Hospital ( Site 0604), Okayama, Not set
Nippon Medical School Hospital ( Site 0608), Tokyo, Not set
Medivest Centro de Investigación Integral ( Site 0183), Chihuahua City, Chihuahua
Higiea Oncologia ( Site 0184), Mexico City, Distrito Federal
Centro de Investigacion Clinica de Oaxaca ( Site 0181), Oaxaca de Juarez., Oaxaca
Samodzielny Publiczny Szpital Kliniczny nr 1 w Lublinie-Oddział Hematoonkologii, Transplantacji Szp ( Site 0463), Lublin, Lubelskie
Pratia Onkologia Katowice ( Site 0461), Katowice, Slaskie
Swietokrzyskie Centrum Onkologii, Samodzielny Publiczny Zakl-Klinika Hematologii i Transplantacji S ( Site 0466), Kielce, Swietokrzyskie
Hospital Germans Trias i Pujol-Instituto Catalán de Oncología de Badalona ( Site 0490), Badalona, Barcelona
Hospital Universitario Marqués de Valdecilla-Haematology ( Site 0486), Santander, Cantabria
HOSPITAL CLÍNIC DE BARCELONA ( Site 0481), Barcelona, Cataluna
Institut Català d'Oncologia - L'Hospitalet ( Site 0482), L'Hospitalet de Llobregat, Cataluna
Clinica Universidad de Navarra-Hematology Department ( Site 0485), Madrid, Madrid, Comunidad De
Hospital Universitario Ramón y Cajal-Hematology ( Site 0484), Madrid, Madrid, Comunidad De
Hospital Costa del Sol-Hematology Service ( Site 0493), Marbella, Malaga
Hospital Universitari Vall d'Hebron-Departamento de Oncologia- VHIO ( Site 0489), Barcelona, Not set
Hospital Universitario 12 de Octubre ( Site 0494), Madrid, Not set
Hospital Universitario de Salamanca - Complejo Asistencial Universitario de Salamanca-Hematology ( Site 0488), Salamanca, Not set
Universitetssjukhuset Örebro ( Site 0542), Örebro, Orebro Lan
Skånes Universitetssjukhus Lund-Department of Hematology ( Site 0544), Lund, Skane Lan
Karolinska Universitetssjukhuset Huddinge ( Site 0541), Huddinge, Stockholms Lan
Akademiska sjukhuset ( Site 0545), Uppsala, Uppsala Lan
Sahlgrenska Universitetssjukhuset-Department of hematology and coagulation ( Site 0543), Gothenburg, Vastra Gotalands Lan
Chang Gung Memorial Hospital- Chiayi ( Site 0242), Chiayi City, Chiayi
National Cheng Kung University Hospital-Clinical Trial Center ( Site 0245), Tainan, Not set
National Taiwan University Hospital ( Site 0241), Taipei, Not set
Chang Gung Medical Foundation-Linkou Branch ( Site 0243), Taoyuan, Not set
Hacettepe Universite Hastaneleri-Department of Hematology ( Site 0505), Ankara, Not set
Medipol Mega Universite Hastanesi ( Site 0504), İstanbul, Not set
Glan Clwyd Hospital ( Site 0528), Bodelwyddan, Denbighshire
Gloucestershire Royal Hospital ( Site 0521), Gloucester, Gloucestershire
Lincoln County Hospital ( Site 0535), Lincoln, Great Britain
Boston Pilgrim Hospital ( Site 0525), Boston, Lincolnshire
University College London Hospital ( Site 0527), London, London, City Of
Guy's & St Thomas' NHS Foundation Trust ( Site 0523), London, London, City Of
Hammersmith Hospital ( Site 0533), London, London, City Of
Royal Gwent Hospital ( Site 0524), Newport, Not set
Conditions: Essential Thrombocythemia
A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)
Recruiting
The purpose of this study is to evaluate if zilovertamab vedotin with standard treatment can help people live longer without the cancer growing or spreading than people who receive standard treatment alone.
The purpose of this study is to evaluate if zilovertamab vedotin with standard treatment can help people live longer without the cancer growing or spreading than people who receive standard treatment alone. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/14/2025
Locations: The University of Arizona Cancer Center - North Campus ( Site 0124), Tucson, Arizona +198 locations
The University of Arizona Cancer Center - North Campus ( Site 0124), Tucson, Arizona
Cancer Blood and Specialty Clinic ( Site 0109), Los Alamitos, California
Cedars-Sinai Medical Center ( Site 0115), Los Angeles, California
Bioresearch Partner ( Site 0157), Hialeah, Florida
Cancer Care Specialists of Illinois ( Site 0152), O'Fallon, Illinois
Fort Wayne Medical Oncology and Hematology ( Site 0149), Fort Wayne, Indiana
Cotton O'Neil Cancer Center ( Site 0108), Topeka, Kansas
Corewell Health ( Site 0130), Grand Rapids, Michigan
Truman Medical Center ( Site 0122), Kansas City, Missouri
OptumCare Cancer Care ( Site 0121), Las Vegas, Nevada
Comprehensive Cancer Centers of Nevada ( Site 0113), Las Vegas, Nevada
New York Oncology Hematology, P.C. ( Site 0129), Albany, New York
The University of Tennessee Medical Center ( Site 0142), Knoxville, Tennessee
University of Virginia Cancer Center ( Site 0138), Charlottesville, Virginia
Virginia Cancer Institute ( Site 0148), Richmond, Virginia
Blue Ridge Cancer Care ( Site 0132), Roanoke, Virginia
SSM Health Dean Medical Group ( Site 0140), Madison, Wisconsin
Clinica Adventista Belgrano ( Site 0309), Caba., Buenos Aires
Instituto de Investigaciones Clinicas Mar del Plata ( Site 0306), Mar del Plata, Buenos Aires
Hospital Universitario Austral ( Site 0307), Pilar, Buenos Aires
Hospital Aleman ( Site 0301), Buenos Aites, Caba
Fundacion Estudios Clinicos ( Site 0311), Rosario., Santa Fe
C.I.C.E. 9 de Julio ( Site 0305), San Miguel de Tucuman, Tucuman
Hospital Italiano de Buenos Aires ( Site 0304), Caba, Not set
Clinica EL Castaño ( Site 0312), San Juan, Not set
Townsville University Hospital ( Site 3006), Douglas, Queensland
Grampians Health ( Site 3003), Ballarat, Victoria
Royal Perth Hospital-Haematology ( Site 3004), Perth, Western Australia
AZ Sint-Maarten, Campus Leopoldstraat 2 ( Site 1102), Mechelen, Antwerpen
ASBL CHU Helora - Hôpital de Mons - Site Kennedy ( Site 1103), Mons, Hainaut
CEONC ( Site 0412), Cascavel, Parana
Hospital Erasto Gaertner ( Site 0401), Curitiba, Parana
Liga Norte Riograndense Contra o Cancer ( Site 0407), Natal, Rio Grande Do Norte
CEPEN - Centro de Pesquisa e Ensino em Oncologia de Santa Catarina ( Site 0403), Florianópolis, Santa Catarina
Hope ( Site 0413), Ribeirao Preto, Sao Paulo
Clinica Advanze ( Site 0411), Sao Carlos, Sao Paulo
F. F. R. M. São Jose do Rio Preto ( Site 0404), Sjrp, Sao Paulo
Hospital Paulistano ( Site 0406), Sao Paulo, Not set
Lakeridge Health - The R.S. McLaughlin Durham Regional Cancer Centre (MDRCC) ( Site 0206), Oshawa, Ontario
Biocenter ( Site 0510), Concepcion., Biobio
IC La Serena Research ( Site 0504), La Serena, Coquimbo
Oncocentro Valdivia ( Site 0506), Valdivia, Los Rios
Centro de Estudios Clínicos SAGA ( Site 0508), Santiago., Region M. De Santiago
Bradfordhill ( Site 0502), Santiago., Region M. De Santiago
FALP ( Site 0501), Santiago, Region M. De Santiago
Clinica Inmunocel ( Site 0503), Santiago, Region M. De Santiago
Clínica RedSalud Vitacura ( Site 0512), Santiago, Region M. De Santiago
Centro de Investigaciones ( Site 0511), Vina del mar, Valparaiso
Anhui Provincial Cancer Hospital ( Site 3124), Hefei, Anhui
Peking University Third Hospital ( Site 3102), Beijing, Beijing
Beijing Cancer Hospital ( Site 3101), Beijing, Beijing
Chongqing Cancer Hospital ( Site 3113), Chongqing, Chongqing
Fujian Provincial Cancer Hospital. ( Site 3119), Fuzhou, Fujian
The First Affiliated Hospital of Xiamen University ( Site 3120), Xiamen, Fujian
Sun Yat-sen University Cancer Center ( Site 3121), Guangzhou, Guangdong
Zhujiang Hospital of Southern Medical University ( Site 3122), Guangzhou, Guangdong
Affiliated Cancer Hospital of Guangxi Medical University ( Site 3123), Nanning, Guangxi
The Affiliated Hospital of Guizhou Medical University ( Site 3112), Guiyang, Guizhou
Hubei Cancer Hospital ( Site 3125), Wuhan, Hubei
Affiliated Hospital of Nantong University ( Site 3117), Nantong, Jiangsu
Jiangxi Cancer Hospital ( Site 3118), Nanchang, Jiangxi
The First Hospital Of Jilin University ( Site 3103), Changchun, Jilin
Shandong Cancer Hospital ( Site 3108), Jinan, Shandong
LinYi Cancer Hospital ( Site 3104), Linyi, Shandong
Fudan University Shanghai Cancer Center ( Site 3115), Shanghai, Shanghai
Shanxi Cancer Hospital ( Site 3106), Taiyuan, Shanxi
1st Affil Hosp of Med College of Xi'an Jiaotong University ( Site 3107), XI An, Shanxi
Sichuan Cancer Hospital. ( Site 3111), Chengdu, Sichuan
West China Hospital, Sichuan University ( Site 3110), Chengdu, Sichuan
Institute of Hematology and Blood Diseases Hosp CAMS&PUMC ( Site 3105), Tianjin, Tianjin
Yunnan Province Cancer Hospital ( Site 3109), Kunming, Yunnan
The First Affiliated Hospital, Zhejiang Medical University ( Site 3116), Hangzhou, Zhejiang
Hospital Pablo Tobon Uribe ( Site 0604), Medellin, Antioquia
IMAT S.A.S ( Site 0603), Montería, Cordoba
Hospital Universitario San Ignacio ( Site 0607), Bogota., Distrito Capital De Bogota
Oncologos del Occidente ( Site 0601), Pereira., Risaralda
Fundación Valle del Lili ( Site 0602), Cali, Valle Del Cauca
Regionshospitalet Gødstrup ( Site 1301), Herning, Midtjylland
Aalborg University Hospital ( Site 1302), Aalborg, Nordjylland
Centre Antoine-Lacassagne ( Site 1514), Nice, Alpes-Maritimes
CHU Dijon Bourgogne ( Site 1516), Dijon, Cote-d Or
Institut Curie - site Saint-Cloud ( Site 1501), Saint-Cloud, Hauts-de-Seine
Centre Hospitalier Universitaire de Limoges - Hôpital Dupuytren ( Site 1512), Limoges, Limousin
Centre Hospitalier Régional Metz Thionville - Hôpital de Mercy ( Site 1515), Metz, Moselle
Centre Hospitalier de Dunkerque ( Site 1513), Dunkerque, Nord
Centre Hospitalier Universitaire Estaing ( Site 1508), Clermont-Ferrand, Puy-de-Dome
Centre Hospitalier de la Cote Basque ( Site 1509), Bayonne, Pyrenees-Atlantiques
HIA Sainte Anne ( Site 1506), Toulon, Var
Centre Hospitalier d'Avignon ( Site 1505), Avignon, Vaucluse
CHD Vendee ( Site 1502), La Roche-sur-Yon, Vendee
Evangelismos General Hospital of Athens ( Site 1602), Athens, Attiki
General Hospital of Athens "Laiko"-Hematology Department ( Site 1603), Athens, Attiki
Attikon University General Hospital of Athens ( Site 1604), Athens, Attiki
University General Hospital of Alexandroupoli ( Site 1601), Alexandroupolis, Evros
CELAN,S.A ( Site 0702), Guatemala., Not set
MEDI-K ( Site 0701), Guatemala, Not set
Cen Integral Onco Gastro y Hemato Onco Guatemala S.A. ( Site 0703), Guatemala, Not set
Princess Margaret Hospital ( Site 3202), Hong Kong, Not set
Queen Mary Hospital ( Site 3201), Hong Kong, Not set
Carmel Hospital ( Site 1903), Haifa, Not set
Hadassah Medical Center ( Site 1901), Jerusalem, Not set
Sourasky Medical Center ( Site 1904), Tel Aviv, Not set
Poria Medical Center ( Site 1902), Tiberias, Not set
Fondazione IRCCS San Gerardo dei Tintori ( Site 2008), Monza, Lombardia
IRCCS Crob ( Site 2002), Rionero in Vulture, Potenza
Istituto di Candiolo IRCCS - Fondazione del Piemonte per l'Oncologia ( Site 2010), Candiolo, Torino
AOU delle Marche Ospedali Riuniti di Ancona ( Site 2011), Ancona, Not set
Azienda Ospedaliera Spedali Civili di Brescia-Hemathology ( Site 2001), Brescia, Not set
IRCCS Ospedale San Raffaele ( Site 2012), Milano, Not set
IEO Istituto Europeo di Oncologia ( Site 2009), Milano, Not set
Azienda Ospedaliero Universitaria Maggiore della Carità ( Site 2004), Novara, Not set
Az. Osp. Ospedali Riuniti VILLA SOFIA-CERVELLO ( Site 2005), Palermo, Not set
Ospedale Santa Maria delle Croci ( Site 2006), Ravenna, Not set
Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore ( Site 2003), Roma, Not set
Nagoya University Hospital ( Site 3309), Nagoya, Aichi
National Hospital Organization Shikoku Cancer Center ( Site 3321), Matsuyama, Ehime
Kobe City Medical Center General Hospital ( Site 3318), Kobe, Hyogo
Kanazawa University Hospital ( Site 3308), Kanazawa, Ishikawa
Tokai University Hospital ( Site 3302), Isehara, Kanagawa
Tohoku University Hospital ( Site 3301), Sendai, Miyagi
Kindai University Hospital ( Site 3310), Osakasayama, Osaka
Saitama Medical University Hospital ( Site 3305), Iruma-gun, Saitama
Juntendo University Hospital ( Site 3307), Bunkyo, Tokyo
University of Yamanashi Hospital ( Site 3320), Chuo, Yamanashi
Chiba Cancer Center ( Site 3314), Chiba, Not set
Kyushu University Hospital ( Site 3313), Fukuoka, Not set
Hiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital ( Site 3322), Hiroshima, Not set
University Hospital,Kyoto Prefectural University of Medicine ( Site 3315), Kyoto, Not set
University of Miyazaki Hospital ( Site 3319), Miyazaki, Not set
Okayama University Hospital ( Site 3311), Okayama, Not set
Osaka Metropolitan University Hospital ( Site 3317), Osaka, Not set
Yamagata University Hospital ( Site 3312), Yamagata, Not set
National Cancer Center- Center for Hemotologic malignancy ( Site 3806), Goyang-si, Kyonggi-do
Pusan National University Hospital ( Site 3804), Busan, Pusan-Kwangyokshi
Chungnam National University Hospital ( Site 3801), Daejeon, Taejon-Kwangyokshi
Severance Hospital, Yonsei University Health System ( Site 3802), Seoul, Not set
Asan Medical Center ( Site 3803), Seoul, Not set
Samsung Medical Center ( Site 3807), Seoul, Not set
St.Mary's H., Youido ( Site 3805), Seoul, Not set
Queen Elizabeth Hospital ( Site 3405), Kota Kinabalu, Sabah
Sarawak General Hospital ( Site 3402), Kuching, Sarawak
Hospital Miri ( Site 3403), Miri, Sarawak
Sunway Medical Centre ( Site 3406), Petaling Jaya, Selangor
Hospital Ampang ( Site 3404), Selangor Darul Ehsan, Selangor
Centro de Infusion Superare ( Site 0804), Ciudad de Mexico, Distrito Federal
Health Pharma Professional Research S.A. de C.V. ( Site 0801), Mexico City, Distrito Federal
Grupo Ollin Care ( Site 0806), Pachuca, Hidalgo
Centro de Investigacion Clinica Chapultepec ( Site 0803), Morelia, Michoacan
Hospital Universitario ""Dr. Jose Eleuterio Gonzalez"" ( Site 0802), Monterrey, Nuevo Leon
Centro de Investigacion Clinica de Oaxaca ( Site 0805), Oaxaca, Not set
Meander Medisch Centrum ( Site 2101), Amersfoort, Utrecht
Albert Schweitzer Ziekenhuis ( Site 2103), Dordrecht, Zuid-Holland
Clínicas AUNA Sede Chiclayo ( Site 0904), Chiclayo, Lambayeque
Clínica San Felipe ( Site 0906), Lima, Not set
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie ( Site 2201), Warszawa, Mazowieckie
Wojewódzki Szpital Specjalistyczny im. J. Korczaka w Słupsku ( Site 2210), Słupsk, Pomorskie
Narodowy Instytut Onkologii - Oddzial w Gliwicach ( Site 2208), Gliwice, Slaskie
Pratia Onkologia Katowice ( Site 2204), Katowice, Slaskie
Szpital Kliniczny Ministerstwa Spraw Wewnętrznych i Administracji z Warmińsko-Mazurskim Centrum Onko ( Site 2205), Olsztyn, Warminsko-mazurskie
Unidade Local de Saude de Braga - Hospital de Braga ( Site 2306), Braga, Not set
Instituto Portugues de Oncologia Do Porto Francisco Gentil E.P.E. ( Site 2302), Porto, Not set
BRCR Global - Mayaguez ( Site 1003), Mayaguez, Not set
Auxilio Mutuo Cancer Center ( Site 1001), San Juan, Not set
Institutul Oncologic Cluj ( Site 2404), Cluj-Napoca, Cluj
Centrul de Diagnostic si Tratament Oncologic Brasov ( Site 2402), Brasov, Not set
Spital Judetean Sibiu ( Site 2405), Sibiu, Not set
National University Hospital ( Site 3702), Singapore, Central Singapore
National Cancer Centre Singapore ( Site 3701), Singapore, Central Singapore
Haemalife ( Site 2501), Cape Town, Western Cape
Hospital Universitario Virgen Macarena ( Site 2608), Sevilla, Andalucia
ICO L Hospitalet ( Site 2601), Hospitalet de Llobregat, Barcelona
H. Insular de Gran Canaria ( Site 2606), Las Palmas de Gran Canaria, Las Palmas
Hospital General Universitario Dr. Balmis ( Site 2604), Alicante, Valenciana, Comunitat
Hospital del Mar ( Site 2610), Barcelona, Not set
Hospital Universitario La Paz ( Site 2611), Madrid, Not set
Hospital Virgen de la Victoria ( Site 2609), Malaga, Not set
Hospital Universitario Miguel Servet ( Site 2607), Zaragoza, Not set
Kantonspital Baden ( Site 2703), Baden, Aargau
Cantonal Hospital St.Gallen-Oncology & Hematology ( Site 2702), St. Gallen, Sankt Gallen
Ospedale Regionale Bellinzona e Valli ( Site 2701), Bellinzona, Ticino
Chang Gung Memorial Hospital - Linkou Branch ( Site 3903), Taoyuan City, Taoyuan
Chang Gung Memorial Hospital at Kaohsiung ( Site 3905), Kaohsiung, Not set
National Cheng Kung University Hospital ( Site 3902), Tainan, Not set
National Taiwan University Hospital ( Site 3901), Taipei, Not set
Mackay Memorial Hospital ( Site 3908), Taipei, Not set
Tri-Service General Hospital ( Site 3906), Taipei, Not set
Maharaj Nakorn Chiang Mai Hospital ( Site 4002), Muang, Chiang Mai
Faculty of Medicine Siriraj Hospital ( Site 4001), Bangkoknoi, Krung Thep Maha Nakhon
Chulalongkorn University ( Site 4003), Pathumwan, Krung Thep Maha Nakhon
Hacettepe Universite Hastaneleri ( Site 2810), Ankara, Not set
Ankara University Faculty of Medicine ( Site 2801), Ankara, Not set
MNPE ClinCenter of Oncology,Hematology,Transplantology and Palliative Care of CherkasyRegCouncil ( Site 2904), Cherkasy, Cherkaska Oblast
Communal non-profit enterprise "Regional clinical hospital of Ivano-Frankivsk Regional Council" ( Site 2906), Ivano-Frankivsk, Ivano-Frankivska Oblast
Khmelnytskyi Regional Hospital ( Site 2907), Khmelnytskiy, Khmelnytska Oblast
Institute of Blood Pathology and Transfusion Medicine AMS Ukraine ( Site 2903), Lviv, Lvivska Oblast
SNPE National Cancer Institute ( Site 2902), Kyiv, Not set
Universal Clinic Oberig ( Site 2908), Kyiv, Not set
SI National Research Center of Radiation Medicine, Hematology, Oncology ( Site 2901), Kyiv, Not set
Public Non-Profit Enterprise Kyiv City Clinical Hospital #9 under the Executive Body of Kyiv City Co ( Site 2905), Kyiv, Not set
Conditions: Diffuse Large B-Cell Lymphoma
A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)
Recruiting
This phase III trial studies using risk factors in determining treatment for children with favorable tissue (histology) Wilms tumors (FHWT). Wilms Tumor is the most common type of kidney cancer in children, and FHWT is the most common subtype. Previous large clinical trials have established treatment plans that are likely to cure most children with FHWT, however some children still have their cancer come back (called relapse) and not all survive. Previous research has identified features of FHWT... Read More
This phase III trial studies using risk factors in determining treatment for children with favorable tissue (histology) Wilms tumors (FHWT). Wilms Tumor is the most common type of kidney cancer in children, and FHWT is the most common subtype. Previous large clinical trials have established treatment plans that are likely to cure most children with FHWT, however some children still have their cancer come back (called relapse) and not all survive. Previous research has identified features of FHWT that are associated with higher or lower risks of relapse. The term "risk" refers to the chance of the cancer coming back after treatment. Using results of tumor histology tests, biology tests, and response to therapy may be able to improve treatment for children with FHWT. Read Less
Gender:
ALL
Ages:
30 years and below
Trial Updated:
08/14/2025
Locations: Children's Hospital of Alabama, Birmingham, Alabama +89 locations
Children's Hospital of Alabama, Birmingham, Alabama
Providence Alaska Medical Center, Anchorage, Alaska
Banner Children's at Desert, Mesa, Arizona
Arkansas Children's Hospital, Little Rock, Arkansas
Loma Linda University Medical Center, Loma Linda, California
Cedars Sinai Medical Center, Los Angeles, California
Kaiser Permanente-Oakland, Oakland, California
Children's Hospital of Orange County, Orange, California
Lucile Packard Children's Hospital Stanford University, Palo Alto, California
University of California Davis Comprehensive Cancer Center, Sacramento, California
Rady Children's Hospital - San Diego, San Diego, California
Children's Hospital Colorado, Aurora, Colorado
Alfred I duPont Hospital for Children, Wilmington, Delaware
Children's National Medical Center, Washington, District of Columbia
Broward Health Medical Center, Fort Lauderdale, Florida
Memorial Regional Hospital/Joe DiMaggio Children's Hospital, Hollywood, Florida
Nemours Children's Clinic-Jacksonville, Jacksonville, Florida
Arnold Palmer Hospital for Children, Orlando, Florida
Nemours Children's Hospital, Orlando, Florida
Nemours Children's Clinic - Pensacola, Pensacola, Florida
Saint Mary's Medical Center, West Palm Beach, Florida
Children's Healthcare of Atlanta - Arthur M Blank Hospital, Atlanta, Georgia
Saint Luke's Cancer Institute - Boise, Boise, Idaho
Lurie Children's Hospital-Chicago, Chicago, Illinois
University of Chicago Comprehensive Cancer Center, Chicago, Illinois
Saint Jude Midwest Affiliate, Peoria, Illinois
Riley Hospital for Children, Indianapolis, Indiana
University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa
University of Kentucky/Markey Cancer Center, Lexington, Kentucky
Children's Hospital New Orleans, New Orleans, Louisiana
Maine Children's Cancer Program, Scarborough, Maine
Sinai Hospital of Baltimore, Baltimore, Maryland
Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland
Dana-Farber Cancer Institute, Boston, Massachusetts
UMass Memorial Medical Center - University Campus, Worcester, Massachusetts
C S Mott Children's Hospital, Ann Arbor, Michigan
Children's Hospital of Michigan, Detroit, Michigan
Mayo Clinic in Rochester, Rochester, Minnesota
University of Mississippi Medical Center, Jackson, Mississippi
Children's Mercy Hospitals and Clinics, Kansas City, Missouri
Cardinal Glennon Children's Medical Center, Saint Louis, Missouri
Washington University School of Medicine, Saint Louis, Missouri
Children's Hospital and Medical Center of Omaha, Omaha, Nebraska
University of Nebraska Medical Center, Omaha, Nebraska
Alliance for Childhood Diseases/Cure 4 the Kids Foundation, Las Vegas, Nevada
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon, New Hampshire
Hackensack University Medical Center, Hackensack, New Jersey
Jersey Shore Medical Center, Neptune, New Jersey
Saint Peter's University Hospital, New Brunswick, New Jersey
Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital, New Brunswick, New Jersey
Newark Beth Israel Medical Center, Newark, New Jersey
Albany Medical Center, Albany, New York
Roswell Park Cancer Institute, Buffalo, New York
NYU Langone Hospital - Long Island, Mineola, New York
Stony Brook University Medical Center, Stony Brook, New York
State University of New York Upstate Medical University, Syracuse, New York
New York Medical College, Valhalla, New York
East Carolina University, Greenville, North Carolina
Children's Hospital Medical Center of Akron, Akron, Ohio
Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
Dayton Children's Hospital, Dayton, Ohio
ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital, Toledo, Ohio
University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
Legacy Emanuel Children's Hospital, Portland, Oregon
Geisinger Medical Center, Danville, Pennsylvania
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania
Rhode Island Hospital, Providence, Rhode Island
Prisma Health Richland Hospital, Columbia, South Carolina
BI-LO Charities Children's Cancer Center, Greenville, South Carolina
East Tennessee Childrens Hospital, Knoxville, Tennessee
Saint Jude Children's Research Hospital, Memphis, Tennessee
Texas Tech University Health Sciences Center-Amarillo, Amarillo, Texas
Dell Children's Medical Center of Central Texas, Austin, Texas
Medical City Dallas Hospital, Dallas, Texas
Cook Children's Medical Center, Fort Worth, Texas
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas
Covenant Children's Hospital, Lubbock, Texas
UMC Cancer Center / UMC Health System, Lubbock, Texas
Children's Hospital of San Antonio, San Antonio, Texas
Methodist Children's Hospital of South Texas, San Antonio, Texas
Primary Children's Hospital, Salt Lake City, Utah
University of Virginia Cancer Center, Charlottesville, Virginia
Children's Hospital of The King's Daughters, Norfolk, Virginia
VCU Massey Comprehensive Cancer Center, Richmond, Virginia
Carilion Children's, Roanoke, Virginia
Providence Sacred Heart Medical Center and Children's Hospital, Spokane, Washington
Mary Bridge Children's Hospital and Health Center, Tacoma, Washington
Saint Vincent Hospital Cancer Center Green Bay, Green Bay, Wisconsin
IWK Health Centre, Halifax, Nova Scotia
Conditions: Stage I Mixed Cell Type Kidney Wilms Tumor, Stage II Mixed Cell Type Kidney Wilms Tumor, Stage III Mixed Cell Type Kidney Wilms Tumor, Stage IV Mixed Cell Type Kidney Wilms Tumor
A Study to Evaluate the Safety, Tolerability of INCB160058 in Participants With Myeloproliferative Neoplasms
Recruiting
This study is being conducted to assess the Safety, Tolerability, and Pharmacokinetics of INCB160058 in Participants With Myeloproliferative Neoplasms.
This study is being conducted to assess the Safety, Tolerability, and Pharmacokinetics of INCB160058 in Participants With Myeloproliferative Neoplasms. Read Less
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/14/2025
Locations: The University of Alabama At Birmingham, Birmingham, Alabama +29 locations
The University of Alabama At Birmingham, Birmingham, Alabama
Stanford University, Palo Alto, California
Moffitt Cancer Center, Tampa, Florida
Northwestern University, Chicago, Illinois
The University of Kansas Cancer Center Kucc University of Kansas Clinical Research Center, Fairway, Kansas
Dana Farber Cancer Institute, Boston, Massachusetts
University of Michigan, Ann Arbor, Michigan
Icahn School of Medicine At Mount Sinai, New York, New York
Cornell Medical Center, New York, New York
Sloan Kettering Institute For Cancer Research, New York, New York
Oregon Health & Science University, Portland, Oregon
University of Pennsylvania Health System, Philadelphia, Pennsylvania
Vanderbilt-Ingram Cancer Center, Nashville, Tennessee
Md Anderson Cancer Center, Houston, Texas
Princess Margaret Cancer Center, Toronto, Ontario
Hopital Maisonneuve-Rosemont, Montreal, Qc, Montreal, Quebec
McGill University Jewish General Hospital, Montreal, Quebec
Hospital Saint Louis, Paris, Not set
Institut Gustave Roussy, Villejuif Cedex, Not set
University Medical Center Rwth Aachen, Aachen, Not set
Universitatsklinikum Essen, Essen, Not set
Universitatsklinikum Halle (Saale), Halle, Not set
Aou Policlinico S. Orsola-Malpighi, Bologna, Not set
Azienda Ospedaliero-Universitaria Careggi (Aouc), Firenze, Not set
Fondazione Irccs Ca Granda Ospedale Maggiore, Milan, Not set
Haukeland University Hospital, Bergen, Not set
Oslo University Hospital, Oslo, Not set
Inselspital - Universitaetsspital Bern, Bern, Not set
Universitatsspital Zurich, Zuerich, Not set
Guys and St Thomas Nhs Foundation Trust, London, Not set
Conditions: Myeloproliferative Neoplasms
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