All Clinical Trials in Canada

A listing of 3905 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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Frequency of Selected Single Nucleotide Polymorphisms in Huntington Disease Gene Expansion Carriers

NCT06667414

Recruiting

For participation in this epidemiological study, a single-day visit at the study site is required. Participants will be recruited from Huntington Disease clinics, and they will be asked to answer questions regarding their demographics, including sex, age, race and ethnicity, and their medical and medication history. At the end of the visit, a blood sample will be drawn to allow testing with a sequencing assay that is specifically designed for phasing single nucleotide polymorphisms (SNPs) on the... Read More

Gender:

ALL

Ages:

Between 25 years and 60 years

Trial Updated:

08/12/2025

Locations: Uab Medicine, Birmingham, Alabama +40 locations

Uab Medicine, Birmingham, Alabama

Barrow Neurological Institute, Phoenix, Arizona

University of California San Diego, La Jolla, California

University of California Davis Medical System, Sacramento, California

CenExel Rocky Mountain Clinical Research, LLC, Englewood, Colorado

University of South Florida, Tampa, Florida

Northwestern University, Chicago, Illinois

University of Iowa Hospitals and Clinics, Iowa City, Iowa

John Hopkins University School of Medicine, Baltimore, Maryland

Beth Israel Deaconess Medical Center, Boston, Massachusetts

University of Pittsburgh, Pittsburgh, Pennsylvania

EvergreenHealth Investigational Drug Services, Kirkland, Washington

Hospital Britanico de Buenos Aires, Ciudad Autonoma Buenos Aires, Not set

Calvary Health Care Bethlehem, Caulfield South, New South Wales

Westmead Hospital, Westmead, New South Wales

Royal Melbourne Hospital, Parkville, Victoria

University of Alberta, Edmonton, Alberta

University of British Columbia Hospital, Vancouver, British Columbia

Centricity Research, Halifax, Nova Scotia

North York General Hospital, Toronto, Ontario

McGill University, Montreal, Quebec

Charité - Universitätsmed. Berlin, Klinik für Psychiatrie und Psychotherapie, Berlin, Not set

St. Josef-Hospital, Neurologische Klinik der Ruhr-Uni, Bochum, Not set

Universitätsklinikum Erlangen, Abteilung Molekulare Neurologie, Erlangen, Not set

Universitätsklinikum Ulm, Ulm, Not set

Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Lombardia

Auckland DHB - Neurlogy Department, Auckland, Not set

New Zealand Brain Research Institute, Christchurch, Not set

Wellington Hospital, Wellington, Not set

Szpital Sw. Wojciecha, Gda?sk, Not set

Wojskowy Instytut Medycyny Lotniczej, Warszawa, Not set

Unidade Local de Saude de Santa Maria, E.P.E. - Hospital de Santa Maria, Lisboa, Not set

CNS - Campus Neurológico, Torres Vedras, Not set

Hospital Universitario de Badajoz, Badajoz, Not set

Hospital de la Santa Creu i Sant Pau, Barcelona, Not set

Hospital Universitario de Burgos. Servicio de Neurología, Burgos, Not set

Hospital Ramon y Cajal, Madrid, Not set

Birmingham and Solihull Mental Health Foundation NHS Trust, Birmingham, Not set

Addenbrookes Hospital, Cambridge, Not set

National Hospital For Neurology and Neurosurgery, London, Not set

John Radcliffe Hospital, Oxford, Not set

Conditions: Huntington Disease

Learn More ›

A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

NCT06819878

Recruiting

This Phase III, multicenter, double-blind, placebo-controlled treat-through study will evaluate the efficacy and safety of induction and maintenance therapy with Afimkibart (also known as RO7790121) in participants with moderately to severely active Crohn's disease (CD).

Gender:

ALL

Ages:

Between 16 years and 80 years

Trial Updated:

08/12/2025

Locations: Digestive Health Specialists of the Southeast (Gastroenterology Associates of Dothan) - Dothan, Dothan, Alabama +180 locations

Digestive Health Specialists of the Southeast (Gastroenterology Associates of Dothan) - Dothan, Dothan, Alabama

Arizona Digestive Health, P.C (ADH), Sun City, Arizona

Valley View Internal Medicine, Garden Grove, California

310 Clinical Research, Inglewood, California

Gastro Care Associates, Lancaster, California

Om Research LLC, Lancaster, California

United Gastroenterologists, Los Alamitos, California

Acclaim Clinical Research, Inc., San Diego, California

UCSF/Medical Center at Mount Zion, San Francisco, California

Rocky Mountain Gastroenterology, Littleton, Colorado

Peak Gastroenterology Surgery Center, Lone Tree, Colorado

Access Research Institute, Brooksville, Florida

Gastro Florida, Clearwater, Florida

HealthMed Clinical Center Inc., Coral Gables, Florida

Hi Tech and Global Research, LLC, Coral Gables, Florida

The Sister Life Research, Hialeah, Florida

NeoClinical Research, Hialeah, Florida

Clinical Research of Osceola, LLC, Kissimmee, Florida

Florida Research Institute - Lakewood, Lakewood Ranch, Florida

LCC Medical Research Institute, LLC, Miami, Florida

Ambert Medical Research, Miami, Florida

Orlando Regional Healthcare, Orlando, Florida

Nodal Medical Center Research - NMC, Tampa, Florida

University of South Florida School of Medicine Morsani Center for Advanced Health Care, Tampa, Florida

Guardian Angel Research Center, LLC, Tampa, Florida

Theia Clinical Research Centers, LLC, Temple Terrace, Florida

Digestive Healthcare of Georgia, Atlanta, Georgia

Atlanta Gastroenterology Associates, Atlanta, Georgia

Gastroenterology Associates of Central Georgia, Macon, Georgia

Grand Teton Research Group, PLLC, Idaho Falls, Idaho

Illinois Gastroenterology Group-Glenview powered by GI Alliance, Glenview, Illinois

GI Alliance - Gurnee, Gurnee, Illinois

Gastroenterology Health Partners, PLLC, New Albany, Indiana

Kansas Gastroenterology, LLC under Clinical Trials Network, Wichita, Kansas

Tri-State Gastroenterology Associates, Crestview Hills, Kentucky

Gastroenterology Health Partners, PLLC, Louisville, Kentucky

Brigham and Women's Hospital, Boston, Massachusetts

Michigan Center of Medical Research, Farmington Hills, Michigan

Gastroenterology Associates and Endoscopy Center of North Mississippi, Oxford, Mississippi

Delta Gastroenterology & Endoscopy Center, Southaven, Mississippi

Las Vegas Clinical Trials, LLC, North Las Vegas, Nevada

Lenox Hill Hospital, New York, New York

DiGiovanna Inst for Med Ed&Res, North Massapequa, New York

Queens Village Medical Care, Queens Village, New York

Gastroenterology Group of Rochester under CTNx, Rochester, New York

Omega Research North Carolina, LLC, Fuquay-Varina, North Carolina

Monroe Biomedical Research, Monroe, North Carolina

Dayton Gastroenterology, Inc., Beavercreek, Ohio

Ohio Gastroenterology Group, Columbus, Ohio

The Ohio State University Wexner Medical Center, Columbus, Ohio

Gastro Intestinal Research Institute of Northern Ohio, Westlake, Ohio

Central Sooner Research, Norman, Oklahoma

Frontier Clinical Re search, LLC, Uniontown, Pennsylvania

University Gastroenterology, Providence, Rhode Island

Gastroenterology Associates, PA PA of Greenville, Greenville, South Carolina

Gastro One, Germantown, Tennessee

Quality Medical Research, Nashville, Tennessee

Texas Clinical Research Institute, LLC, Arlington, Texas

Proactive El Paso,LLC, El Paso, Texas

Amel Med LLC, Georgetown, Texas

Cano Medical Center, Harlingen, Texas

TDDC dba GI Alliance Research, Mansfield, Texas

SMS Clinical Research, LLC, Mesquite, Texas

Gastroenterology Research of America, LLC, San Antonio, Texas

GI Alliance - Southlake, Southlake, Texas

Tyler Research Institute, LLC, Tyler, Texas

Tidewater Gastroenterology Pllc T/A Gastro. Assoc. of Tidewater, Chesapeake, Virginia

Emeritas Research Group, Lansdowne Town Center, Virginia

Gastroenterology Consultants and Endoscopy Center of Southwest Virginia, Roanoke, Virginia

Tidewater Physicians Multispecialty Group (TPMG) - Clinical Research Division - Williamsburg, Williamsburg, Virginia

The Vancouver Clinic, Vancouver, Washington

Hospital Britanico, Ciudad Autonoma Bs As, Not set

Royal Prince Alfred Hospital, Sydney, New South Wales

Mater Misericordiae Limited, South Brisbane, Queensland

Barmherzige Brüder Wien, Wien, Not set

Medizinische Universität Wien, Wien, Not set

AZORG Campus Aalst-Moorselbaan, Aalst, Not set

Cliniques Universitaires St-Luc, Bruxelles, Not set

UZ Antwerpen, Edegem, Not set

AZ Maria Middelares, Gent, Not set

AZ Sint Lucas (Sint Lucas), Gent, Not set

Jessa Zkh (Campus Virga Jesse), Hasselt, Not set

CHC MontLégia, Liege, Not set

CHU de Liège (Sart Tilman), Liège, Not set

CHU HELORA - Hôpital de Mons - Site Kennedy, Mons, Not set

Vitaz, Sint Niklaas, Not set

Hospital de Clinicas de Porto Alegre X, Porto Alegre, Rio Grande Do Sul

CPQuali Pesquisa Clinica Ltda, Sao Paulo, São Paulo

South Edmonton Gastroenterology, Edmonton, Alberta

C.I.C. Mauricie, Trois-rivieres, Quebec

Hospital Guillermo Grant Benavente, Concepcion, Not set

Medwal, Santiago, Not set

Clinica Universidad de Los Andes, Santiago, Not set

Peking University Third Hospital, Beijing, Not set

the First Hospital of Jilin University, Changchun, Not set

Third Xiangya Hospital Centrel South University, Changsha, Not set

West China Hospital of Sichuan University, Chengdu City, Not set

Chongqing General Hospital, Chongqing City, Not set

The First Affiliated Hospital Of Fujian Medical University, Fuzhou City, Not set

The second Affiliated Hospital of Guangzhou Medical University, Guangzhou City, Not set

The sixth affiliated hospital of Sun Yat-Sen University, Guangzhou City, Not set

Zhejiang Province Traditional Chinese Medical Hospital, Hangzhou City, Not set

Sir Run Run Shaw Hospital Zhejiang University, Hangzhou City, Not set

Anhui Provincial Hospital, Hefei, Not set

The First Affiliated Hospital of Anhui Medical University, Hefei, Not set

Huizhou Central People's Hospital, Huizhou, Not set

The 1st Affiliated Hospital of Nanchang Unversity, Nanchang City, Not set

The First Affiliate Hospital of Guangxi Medical University, Nanning, Not set

The First Affiliated Hospital of Ningbo University, Ningbo City, Not set

Shanghai East Hospital, Shanghai City, Not set

Peking University Shenzhen Hospital, Shenzhen, Not set

Taizhou Hospital Of Zhejiang Province, Taizhou City, Not set

The Central Hospital of Wuhan, Wuhan City, Not set

Ren Min Hospital Affiliated Wu Han University, Wuhan, Not set

Wuxi People's Hospital, Wuxi, Not set

Zhongshan Hospital Xiamen University, Xiamen, Not set

The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Not set

Zhuzhou Central Hospital, Zhuzhou, Not set

SurGal Clinic s.r.o., Brno, Not set

Gastroenterologie s.r.o., Hradec Kralove, Not set

Fakultni nemocnice Hradec Kralove, Hradec Kralove, Not set

Herlev Hospital, Herlev, Not set

CEMDOE (Centro Médico de Diabetes, Obesidad y Especialidades), Santo Domingo, Not set

CHU Amiens - Hopital Sud, Amiens, Not set

Hopital Nord, Marseille, Not set

CHU Nice - Hopital de l'Archet 2, Nice, Not set

CHU Bordeaux - Hôpital Haut-Lévêque, Pessac, Not set

Hopital Robert Debre, Reims, Not set

CHU de Rennes - Hopital de Pontchaillo, Rennes, Not set

CHU Saint Etienne - Hôpital Nord, Saint Etienne, Not set

Charite - Campus Benjamin Franklin, Berlin, Not set

AGAPLESION Markus-Krankenhaus, Frankfurt, Not set

Klinik Johann Wolfgang von Goethe Uni, Frankfurt, Not set

Universitaetsklinikum Halle (Saale), Halle, Not set

Universitaetsklinikum Jena, Jena, Not set

Klinikum Mannheim GmbH Universitätsklinikum, Mannheim, Not set

Universitätsklinikum Ulm, Ulm, Not set

Obudai Egeszsegugyi Centrum Kft., Budapest, Not set

Semmelweis Egyetem, Budapest, Not set

Pannonia Maganorvosi Centrum, Budapest, Not set

Clinexpert Gyongyos Kft, Gyongyos, Not set

Clinfan Szolgaltato Kft., Szekszard, Not set

Fejer Varmegyei Szent György Egyetemi Oktatokorhaz, Székesfehérvár, Not set

Chaim Sheba Medical Center, Ramat Gan, Not set

Ospedale Isola Tiberina Gemelli, Roma, Lazio

ASST Rhodense - Ospedale di Rho, Rho, Lombardia

Ospedale Mauriziano Umberto I, Torino, Piemonte

Gamagori City Hospital, Aichi, Not set

Tsujinaka Hospital Kashiwanoha, Chiba, Not set

Kinshukai Infusion Clinic, Osaka, Not set

Matsuda Hospital, Shizuoka, Not set

Boca Clinical Trials Mexico S.C. (Guadalajara), Guadalajara, Jalisco

Medical Care & Research SA de CV, Mérida, Yucatan

Universitair Medisch Centrum Utrecht, Utrecht, Not set

Centrum Medyczne "Medis", Bydgoszcz, Not set

Centrum Medyczne Lukamed Joanna Luka-Wendrowska, Chojnice, Not set

Endo-Med Sp. z o.o., Karczew, Not set

Allmedica Badania Kliniczne Sp z o.o. Sp K., Nowy Targ, Not set

SOLUMED Centrum Medyczne, Pozna?, Not set

Gastromed Sp. z o.o., Toru?, Not set

WIP Warsaw IBD Point Profesor Kierkus, Warszawa, Not set

Centralny Szpital Kliniczny MSW w Warszawie, Warszawa, Not set

Przychodnia EuroMediCare, Wroc?aw, Not set

Melita Medical, Wroc?aw, Not set

Vistamed & Vertigo Spó?Ka Z Ograniczon? Odpowiedzialno?Ci?, Wroc?aw, Not set

ETG Zamosc, Zamosc, Not set

Hospital de Braga, Braga, Not set

Hospital de Santa Maria, Lisboa, Not set

Hospital de Sao Joao, Porto, Not set

Klinical Investigations Group LLC, San Juan, Not set

Hospital Universitario Marques de Valdecilla, Santander, Cantabria

Hospital Universitario La Paz, Madrid, Not set

Hospital Universitario Reina Sofía, Murcia, Not set

China Medical University Hospital, Taichung City, Not set

Division of Gastroenterology, Depart of Medicine, Fac of Med., Chulalongkorn University, Bangkok, Not set

Division of Gastroenterology, Depart of Internal Med, Siriraj H, Mahidol Uni, Bangkok, Not set

Khon Kaen Uni, Khon Kaen, Not set

Division of Gastroenterology, Depart of Medicine, Fac. of Med, Songklanagarind University, Songkhla, Not set

Royal Liverpool University Hospital, Liverpool, Not set

King College Hospital NHS Foundation Trust, London, Not set

Queen Anne Street Medical Centre, London, Not set

Conditions: Moderately to Severely Active Crohns Disease

Learn More ›

Safety and Efficacy of PC945 (Opelconazole) in Combination With Other Antifungal Therapy for the Treatment of Refractory Invasive Pulmonary Aspergillosis (OPERA-T Study)

NCT05238116

Recruiting

To assess the safety and efficacy of nebulized PC945 in combination with systemic antifungal therapy for the treatment of refractory IPA

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/12/2025

Locations: Clinical Research Site 029, Duarte, California +101 locations

Clinical Research Site 029, Duarte, California

Clinical Research Site 009, La Jolla, California

Clinical Research Site 122, Los Angeles, California

Clinical R Site 024, Los Angeles, California

Clinical Research Site 119, Sacramento, California

Clinical Research Site 031, Jacksonville, Florida

Clinical Research Site 022, Indianapolis, Indiana

Clinical Research Site 023, Lexington, Kentucky

Clinical Research Site 121, Baltimore, Maryland

Clinical Research Site 025, Boston, Massachusetts

Clinical Research Site 111, Ann Arbor, Michigan

Clinical Research Site 095, Minneapolis, Minnesota

Clinical Research Site 010, Saint Louis, Missouri

Clinical Research Site 018, Bronx, New York

Clinical Research Site 002, Philadelphia, Pennsylvania

Clinical Research Site 001, Pittsburgh, Pennsylvania

Clinical Research Site 030, Nashville, Tennessee

Clinical Research Site 003, Houston, Texas

Clinical Research Site 028, Houston, Texas

Clinical Research Site 118, Houston, Texas

Clinical Research Site 026, Seattle, Washington

Clinical Research Site 032, Madison, Wisconsin

Clinical Research Site 034, Buenos Aires, Not set

Clinical Research Site 033, Buenos Aires, Not set

Clinical Research Site 035, Buenos Aires, Not set

Clinical Research Site 108, Mendoza, Not set

Clinical Research Site 109, Santa Fe, Not set

Clinical Research Site 106, Melbourne, Parkville

Clinical Research Site 107, Melbourne, Victoria

Clinical Research Site 037, Graz, Not set

Clinical Research Site 036, Vienna, Not set

Clinical Research Site 098, Brussels, Not set

Clinical Research Site 038, Brussels, Not set

Clinical Research Site 039, Leuven, Not set

Clinical Research Site 044, Paraná, Curitiba

Clinical Research Site 040, Paranã, Curitiba

Clinical Research Site 042, São Paulo, Santos

Clinical Research Site 047, Rio Grande, Not set

Clinical Research Site 046, Rio Grande, Not set

Clinical Research Site 045, Rio Grande, Not set

Clinical Research Site 043, Santa Catarina, Not set

Clinical Research Site 041, São Paulo, Not set

Clinical Research Site 008, Toronto, Ontario

Clinical Research Site 110, Toronto, Ontario

Clinical Research Site 096, Hamilton, Not set

Clinical Research Site 049, Santiago, Not set

Clinical Research Site 048, Valparaíso, Not set

Clinical Research Site 051, Medellín, Not set

Clinical Research Site 050, Montería, Not set

Clinical Research Site 123, Valle, Not set

Clinical Research Site 060, Bordeaux, Not set

Clinical Research Site 097, Paris, Not set

Clinical Research Site 059, Strasbourg, Not set

Clinical Research Site 071, Würzburg, Bavaria

Clinical Research Site 069, Frankfurt, Hesse

Clinical Research Site 070, Cologne, Not set

Clinical Research Site 073, Exochí, Thessalonk

Clinical Research Site 072, Athens, Not set

Clinical Research Site104, Karna, Karnataka

Clinical Research Site 099, Pune, Maharashtra

Clinical Research Site 103, Hyderabad, Not set

Clinical Research Site 100, Hyderabad, Not set

Clinical Research Site 101, New Delhi, Not set

Clinical Research Site 102, Pune, Not set

Clinical Research Site 076, Haifa, Not set

Clinical Research Site 075, Ramat Gan, Not set

Clinical Research Site 074, Safed, Not set

Clinical Research Site 081, Brescia, Not set

Clinical Research Site 080, Milan, Not set

Clinical Research Site 077, Monza, Not set

Clinical Research Site 079, Naples, Not set

Clinical Research Site 078, Rome, Not set

Clinical Research Site 082, Siena, Not set

Clinical Research Site 086, Daejeon, Not set

Clinical Research Site 083, Gyeonggi do, Not set

Clinical Research Site 084, Incheon, Not set

Clinical Research Site 089, Seoul, Not set

Clinical Research Site 085, Seoul, Not set

Clinical Research Site 088, Seoul, Not set

Clinical Research Site 087, Seoul, Not set

Clinical Research Site 054, Barcelona, Not set

Clinical Research Site 057, Barcelona, Not set

Clinical Research Site 052, Córdoba, Not set

Clinical Research Site 053, Granada, Not set

Clinical Research Site 058, Madrid, Not set

Clinical Research Site 056, Santander, Not set

Clinical Research Site 055, Valencia, Not set

Clinical Research Site 094, Taipei, New Tapai City

Clinical Research Site 090, Tapei City, Tapai

Clinical Research Site 092, Kaohsiung, Not set

Clinical Research Site 091, New Taipei City, Not set

Clinical Research Site 093, Tainan, Not set

Clinical Research Site 113, Bangkok, Not set

Clinical Research Site 112, Bangkok, Not set

Clinical Research Site 114, Khon Kaen, Not set

Clinical Research Site 115, Pathum Thani, Not set

Clinical Research Site 065, Cambridge, Not set

Clinical Research Site 066, Harefield, Not set

Clinical Research Site 063, London, Not set

Clinical Research Site 062, London, Not set

Clinical Research Site 064, London, Not set

Clinical Research Site 067, Manchester, Not set

Conditions: Refractory IPA

Learn More ›

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

NCT06422806

Recruiting

This phase III trial compares the effect of immunotherapy (pembrolizumab) plus chemotherapy (doxorubicin) to chemotherapy (doxorubicin) alone in treating patients with undifferentiated pleomorphic sarcoma (UPS) or a related poorly differentiated sarcoma that has spread from where it first started (primary site) to other places in the body (metastatic) or that cannot be removed by surgery (unresectable). Doxorubicin is in a class of medications called anthracyclines. Doxorubicin damages the cell'... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/12/2025

Locations: Mayo Clinic Hospital in Arizona, Phoenix, Arizona +198 locations

Mayo Clinic Hospital in Arizona, Phoenix, Arizona

Banner University Medical Center - Tucson, Tucson, Arizona

University of Arizona Cancer Center-North Campus, Tucson, Arizona

Kaiser Permanente Dublin, Dublin, California

Kaiser Permanente-Fremont, Fremont, California

Kaiser Permanente-Fresno, Fresno, California

Keck Medicine of USC Koreatown, Los Angeles, California

Los Angeles General Medical Center, Los Angeles, California

USC / Norris Comprehensive Cancer Center, Los Angeles, California

Cedars Sinai Medical Center, Los Angeles, California

Kaiser Permanente-Modesto, Modesto, California

USC Norris Oncology/Hematology-Newport Beach, Newport Beach, California

Kaiser Permanente-Oakland, Oakland, California

Stanford Cancer Institute Palo Alto, Palo Alto, California

Kaiser Permanente-Roseville, Roseville, California

Kaiser Permanente Downtown Commons, Sacramento, California

Kaiser Permanente-South Sacramento, Sacramento, California

Kaiser Permanente-San Francisco, San Francisco, California

UCSF Medical Center-Mission Bay, San Francisco, California

Kaiser Permanente-Santa Teresa-San Jose, San Jose, California

Kaiser Permanente San Leandro, San Leandro, California

Kaiser San Rafael-Gallinas, San Rafael, California

Kaiser Permanente Medical Center - Santa Clara, Santa Clara, California

Kaiser Permanente-Santa Rosa, Santa Rosa, California

Kaiser Permanente-South San Francisco, South San Francisco, California

Kaiser Permanente-Vallejo, Vallejo, California

Kaiser Permanente-Walnut Creek, Walnut Creek, California

UCHealth University of Colorado Hospital, Aurora, Colorado

Poudre Valley Hospital, Fort Collins, Colorado

Cancer Care and Hematology-Fort Collins, Fort Collins, Colorado

UCHealth Greeley Hospital, Greeley, Colorado

Medical Center of the Rockies, Loveland, Colorado

Beebe South Coastal Health Campus, Millville, Delaware

Helen F Graham Cancer Center, Newark, Delaware

Medical Oncology Hematology Consultants PA, Newark, Delaware

Beebe Health Campus, Rehoboth Beach, Delaware

UM Sylvester Comprehensive Cancer Center at Coral Gables, Coral Gables, Florida

UM Sylvester Comprehensive Cancer Center at Coral Springs, Coral Springs, Florida

UM Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach, Florida

University of Florida Health Science Center - Gainesville, Gainesville, Florida

UM Sylvester Comprehensive Cancer Center at Hollywood, Hollywood, Florida

Mayo Clinic in Florida, Jacksonville, Florida

University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida

UM Sylvester Comprehensive Cancer Center at Kendall, Miami, Florida

UM Sylvester Comprehensive Cancer Center at Plantation, Plantation, Florida

Emory University Hospital Midtown, Atlanta, Georgia

Kaiser Permanente Moanalua Medical Center, Honolulu, Hawaii

Saint Alphonsus Cancer Care Center-Boise, Boise, Idaho

Saint Alphonsus Cancer Care Center-Caldwell, Caldwell, Idaho

Kootenai Health - Coeur d'Alene, Coeur d'Alene, Idaho

Saint Alphonsus Cancer Care Center-Nampa, Nampa, Idaho

Kootenai Clinic Cancer Services - Post Falls, Post Falls, Idaho

Kootenai Clinic Cancer Services - Sandpoint, Sandpoint, Idaho

Advocate Outpatient Center - Aurora, Aurora, Illinois

Advocate Good Shepherd Hospital, Barrington, Illinois

Illinois CancerCare-Bloomington, Bloomington, Illinois

Illinois CancerCare-Canton, Canton, Illinois

Illinois CancerCare-Carthage, Carthage, Illinois

Centralia Oncology Clinic, Centralia, Illinois

Northwestern University, Chicago, Illinois

University of Illinois, Chicago, Illinois

University of Chicago Comprehensive Cancer Center, Chicago, Illinois

Advocate Illinois Masonic Medical Center, Chicago, Illinois

AMG Crystal Lake - Oncology, Crystal Lake, Illinois

Carle at The Riverfront, Danville, Illinois

Cancer Care Specialists of Illinois - Decatur, Decatur, Illinois

Decatur Memorial Hospital, Decatur, Illinois

Northwestern Medicine Cancer Center Kishwaukee, DeKalb, Illinois

Illinois CancerCare-Dixon, Dixon, Illinois

Advocate Good Samaritan Hospital, Downers Grove, Illinois

Carle Physician Group-Effingham, Effingham, Illinois

Crossroads Cancer Center, Effingham, Illinois

Advocate Sherman Hospital, Elgin, Illinois

Elmhurst Memorial Hospital, Elmhurst, Illinois

Illinois CancerCare-Eureka, Eureka, Illinois

Illinois CancerCare-Galesburg, Galesburg, Illinois

Northwestern Medicine Cancer Center Delnor, Geneva, Illinois

Northwestern Medicine Glenview Outpatient Center, Glenview, Illinois

Northwestern Medicine Grayslake Outpatient Center, Grayslake, Illinois

Ingalls Memorial Hospital, Harvey, Illinois

Advocate South Suburban Hospital, Hazel Crest, Illinois

Illinois CancerCare-Kewanee Clinic, Kewanee, Illinois

Northwestern Medicine Lake Forest Hospital, Lake Forest, Illinois

AMG Libertyville - Oncology, Libertyville, Illinois

Condell Memorial Hospital, Libertyville, Illinois

Illinois CancerCare-Macomb, Macomb, Illinois

Carle Physician Group-Mattoon/Charleston, Mattoon, Illinois

Edward Hospital/Cancer Center, Naperville, Illinois

UC Comprehensive Cancer Center at Silver Cross, New Lenox, Illinois

Cancer Care Center of O'Fallon, O'Fallon, Illinois

Advocate Christ Medical Center, Oak Lawn, Illinois

Northwestern Medicine Orland Park, Orland Park, Illinois

University of Chicago Medicine-Orland Park, Orland Park, Illinois

Illinois CancerCare-Ottawa Clinic, Ottawa, Illinois

Advocate Lutheran General Hospital, Park Ridge, Illinois

Illinois CancerCare-Pekin, Pekin, Illinois

Illinois CancerCare-Peoria, Peoria, Illinois

Illinois CancerCare-Peru, Peru, Illinois

Edward Hospital/Cancer Center?Plainfield, Plainfield, Illinois

Illinois CancerCare-Princeton, Princeton, Illinois

Southern Illinois University School of Medicine, Springfield, Illinois

Springfield Clinic, Springfield, Illinois

Springfield Memorial Hospital, Springfield, Illinois

Carle Cancer Center, Urbana, Illinois

Northwestern Medicine Cancer Center Warrenville, Warrenville, Illinois

Illinois CancerCare - Washington, Washington, Illinois

UChicago Medicine Northwest Indiana, Crown Point, Indiana

Indiana University/Melvin and Bren Simon Cancer Center, Indianapolis, Indiana

Sidney and Lois Eskenazi Hospital, Indianapolis, Indiana

UI Health Care Mission Cancer and Blood - Ankeny Clinic, Ankeny, Iowa

Saint Anthony Regional Hospital, Carroll, Iowa

UI Health Care Mission Cancer and Blood - Des Moines Clinic, Des Moines, Iowa

Broadlawns Medical Center, Des Moines, Iowa

UI Healthcare Mission Cancer and Blood - Fort Dodge, Fort Dodge, Iowa

University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa

The James Graham Brown Cancer Center at University of Louisville, Louisville, Kentucky

UofL Health Medical Center Northeast, Louisville, Kentucky

Louisiana Hematology Oncology Associates LLC, Baton Rouge, Louisiana

Dana-Farber Cancer Institute, Boston, Massachusetts

University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan

Henry Ford Macomb Hospital-Clinton Township, Clinton Township, Michigan

Henry Ford Hospital, Detroit, Michigan

Henry Ford Medical Center-Columbus, Novi, Michigan

Sanford Joe Lueken Cancer Center, Bemidji, Minnesota

Essentia Health - Deer River Clinic, Deer River, Minnesota

Essentia Health Cancer Center, Duluth, Minnesota

Essentia Health Hibbing Clinic, Hibbing, Minnesota

Mayo Clinic in Rochester, Rochester, Minnesota

Essentia Health Sandstone, Sandstone, Minnesota

Essentia Health Virginia Clinic, Virginia, Minnesota

Washington University School of Medicine, Saint Louis, Missouri

Siteman Cancer Center-South County, Saint Louis, Missouri

Community Hospital of Anaconda, Anaconda, Montana

Billings Clinic Cancer Center, Billings, Montana

Bozeman Health Deaconess Hospital, Bozeman, Montana

Benefis Sletten Cancer Institute, Great Falls, Montana

Logan Health Medical Center, Kalispell, Montana

Community Medical Center, Missoula, Montana

Nebraska Medicine-Bellevue, Bellevue, Nebraska

Nebraska Medicine-Village Pointe, Omaha, Nebraska

University of Nebraska Medical Center, Omaha, Nebraska

Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon, New Hampshire

Roswell Park Cancer Institute, Buffalo, New York

Northwell Health/Center for Advanced Medicine, Lake Success, New York

Duke University Medical Center, Durham, North Carolina

Sanford Bismarck Medical Center, Bismarck, North Dakota

Sanford Broadway Medical Center, Fargo, North Dakota

Sanford Roger Maris Cancer Center, Fargo, North Dakota

UH Seidman Cancer Center at UH Avon Health Center, Avon, Ohio

UHHS-Chagrin Highlands Medical Center, Beachwood, Ohio

Miami Valley Hospital South, Centerville, Ohio

Case Western Reserve University, Cleveland, Ohio

Cleveland Clinic Foundation, Cleveland, Ohio

Ohio State University Comprehensive Cancer Center, Columbus, Ohio

Miami Valley Hospital, Dayton, Ohio

Premier Blood and Cancer Center, Dayton, Ohio

Miami Valley Hospital North, Dayton, Ohio

Atrium Medical Center-Middletown Regional Hospital, Franklin, Ohio

Miami Valley Cancer Care and Infusion, Greenville, Ohio

Upper Valley Medical Center, Troy, Ohio

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Saint Alphonsus Cancer Care Center-Ontario, Ontario, Oregon

Oregon Health and Science University, Portland, Oregon

Pennsylvania Hospital, Philadelphia, Pennsylvania

Thomas Jefferson University Hospital, Philadelphia, Pennsylvania

Fox Chase Cancer Center, Philadelphia, Pennsylvania

Allegheny General Hospital, Pittsburgh, Pennsylvania

University of Pittsburgh Cancer Institute (UPCI), Pittsburgh, Pennsylvania

Medical University of South Carolina, Charleston, South Carolina

Sanford Cancer Center Oncology Clinic, Sioux Falls, South Dakota

Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota

Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee

University of Virginia Cancer Center, Charlottesville, Virginia

VCU Massey Comprehensive Cancer Center, Richmond, Virginia

Duluth Clinic Ashland, Ashland, Wisconsin

Aurora Cancer Care-Southern Lakes VLCC, Burlington, Wisconsin

Aurora Saint Luke's South Shore, Cudahy, Wisconsin

Aurora Health Care Germantown Health Center, Germantown, Wisconsin

Aurora Cancer Care-Grafton, Grafton, Wisconsin

Aurora BayCare Medical Center, Green Bay, Wisconsin

Aurora Cancer Care-Kenosha South, Kenosha, Wisconsin

Aurora Bay Area Medical Group-Marinette, Marinette, Wisconsin

Aurora Cancer Care-Milwaukee, Milwaukee, Wisconsin

Aurora Saint Luke's Medical Center, Milwaukee, Wisconsin

Medical College of Wisconsin, Milwaukee, Wisconsin

Aurora Sinai Medical Center, Milwaukee, Wisconsin

ProHealth D N Greenwald Center, Mukwonago, Wisconsin

ProHealth Oconomowoc Memorial Hospital, Oconomowoc, Wisconsin

Vince Lombardi Cancer Clinic - Oshkosh, Oshkosh, Wisconsin

Aurora Cancer Care-Racine, Racine, Wisconsin

Vince Lombardi Cancer Clinic-Sheboygan, Sheboygan, Wisconsin

Aurora Medical Center in Summit, Summit, Wisconsin

Vince Lombardi Cancer Clinic-Two Rivers, Two Rivers, Wisconsin

ProHealth Waukesha Memorial Hospital, Waukesha, Wisconsin

UW Cancer Center at ProHealth Care, Waukesha, Wisconsin

Aurora Cancer Care-Milwaukee West, Wauwatosa, Wisconsin

Aurora West Allis Medical Center, West Allis, Wisconsin

CancerCare Manitoba, Winnipeg, Manitoba

University Health Network-Princess Margaret Hospital, Toronto, Ontario

Conditions: Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8, Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8, Metastatic Undifferentiated Pleomorphic Sarcoma, Unresectable Undifferentiated Pleomorphic Sarcoma

Learn More ›

Using Cannabis to Treat Restless Legs Syndrome

NCT06863740

Recruiting

Restless Legs Syndrome (RLS) is a disorder that causes painful and uncomfortable sensations in the legs, and its symptoms have a significant impact on sleep and quality of life. Cannabis has been used by some RLS patients as a treatment due to its painkilling and drowsiness effects, however there has never been a clinical research trial investigating cannabis in patients with RLS. A controlled trial is needed to establish how safe and feasible cannabis is as a treatment for RLS. The investigator... Read More

Gender:

ALL

Ages:

25 years and above

Trial Updated:

08/12/2025

Locations: Sunnybrook Health Sciences Centre, Toronto, Ontario +1 locations

Conditions: Restless Leg Syndrome (RLS)

Learn More ›

Akkermansia Muciniphilia and Metabolic Side Effects of ADT

NCT05802121

Recruiting

The overriding objectives of this study are: 1. Primary outcomes: 1. To confirm that administration of oral acetate increases the proportion of A. muciniphilia in the stool samples of patients with metastatic, castration-sensitive prostate cancer compared to placebo. 2. To confirm tolerability and assess for side effects of delayed oral acetate supplementation. 2. Secondary outcomes: 1. To determine if increased counts of A. muciniphilia correlate with improved metabolic parameters a... Read More

Gender:

MALE

Ages:

18 years and above

Trial Updated:

08/12/2025

Locations: London Health Sciences Centre - Victoria Hospital, London, Ontario

Conditions: Prostate Cancer, Metabolic Syndrome, Obesity, Cardiovascular Morbidity, Bone Diseases, Hyperlipidemias, Diabetes

Learn More ›

A Long-term Safety and Efficacy Study Evaluating APG777 in Atopic Dermatitis

NCT07003425

Recruiting

This is a multicenter, double-blind, Long-Term Extension (LTE) study to evaluate the long-term safety and efficacy of APG777 in patients with moderate-to-severe AD who have completed treatment in an APG777 Parent Study (NCT06395948). The LTE study will consist of 3 periods: 1) Screening Visit will coincide with the last visit of the Maintenance Period in the Parent Study 2) Extended Treatment Period 3) Post-treatment Follow-up Period. This study will be conducted in participants with atopic de... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/12/2025

Locations: Investigational Site, Fountain Valley, California +31 locations

Investigational Site, Fountain Valley, California

Investigational Site, Coral Gables, Florida

Investigational Site, Margate, Florida

Investigational Site, Detroit, Michigan

Investigational Site, Troy, Michigan

Investigational Site, Wilmington, North Carolina

Investigational Site, Boardman, Ohio

Investigational Site, Mason, Ohio

Investigational Site, Portland, Oregon

Investigational Site, Nashville, Tennessee

Investigational Site, Frisco, Texas

Investigational Site, San Antonio, Texas

Investigational Site, Calgary, Alberta

Investigational Site, Edmonton, Alberta

Investigational Site, Fredericton, Brunswick

Investigational Site, Markham, Ontario

Investigational Site, Mississauga, Ontario

Investigational Site, Peterborough, Ontario

Investigational Site, Toronto, Ontario

Investigational Site, Montréal, Quebec

Investigational Site, Quebec City, Quebec

Investigational Site, Wrocław, Dolnoslaskie

Investigational Site, Wrocław, Dolnośląskie

Investigational Site, Lublin, Lubelskie

Investigational Site, Warszawa, Mazowieckie

Investigational Site, Gdańsk, Pomorskie

Investigational Site, Katowice, Silesia

Investigational Site, Sosnowiec, Silesia

Investigational Site, Kraków, Woj. Małopolskie

Investigational Site, Łódź, Not set

Conditions: Atopic Dermatitis

Learn More ›

A Trial That Evaluates Disease Characteristics in Hemophilia B Adult Male Participants Receiving Prophylaxis With Standard of Care Factor IX Protein (FIX) Replacement Therapy

NCT05568459

Recruiting

This study is focused on males who have Hemophilia B and who need regular preventive treatment with factor IX protein (FIX) replacement therapy to prevent and also to control their bleeding events. The aim of the study is to gather at least 6 months of information on bleeding events for each individual participant while they continue to use their usual FIX replacement therapy. There is no experimental treatment being tested in this study. The study is informational, and part of a larger program... Read More

Gender:

MALE

Ages:

16 years and above

Trial Updated:

08/12/2025

Locations: Orthopaedic Hemophilia Treatment Center, Los Angeles, California +21 locations

Conditions: Hemophilia B

Learn More ›

A Study to Assess the Adverse Events, Change in Disease Activity, and How Intravenously Infused ABBV-319 Moves Through the Bodies of Adult Participants With Relapsed or Refractory (R/R) Diffuse Large B-cell Lymphoma (DLBCL), Follicular Lymphoma (FL), or Chronic Lymphocytic Leukemia (CLL)

NCT05512390

Recruiting

B-cell Lymphoma is an aggressive and rare cancer of a type of immune cells (a white blood cell responsible for fighting infections). Follicular Lymphoma is a slow-growing type of non-Hodgkin lymphoma. Chronic lymphocytic leukemia (CLL) is the most common leukemia (cancer of blood cells). The purpose of this study is to assess the safety, tolerability, pharmacokinetics, and preliminary efficacy of ABBV-319 in adult participants in relapsed or refractory (R/R) diffuse large b-cell lymphoma (DLBCL)... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/12/2025

Locations: University of Arizona Cancer Center - Tucson /ID# 247752, Tucson, Arizona +17 locations

Conditions: Diffuse Large B-Cell Lymphoma, Chronic Lymphocytic Leukemia, Follicular Lymphoma

Learn More ›

Sacituzumab Tirumotecan (MK-2870) Versus Chemotherapy in Previously Treated Advanced or Metastatic Nonsquamous Non-small Cell Lung Cancer (NSCLC) With EGFR Mutations or Other Genomic Alterations (MK-2870-004)

NCT06074588

Recruiting

The purpose of this study is to evaluate sacituzumab tirumotecan versus chemotherapy (docetaxel or pemetrexed) for the treatment of previously-treated non-small cell lung cancer (NSCLC) with exon 19del or exon 21 L858R EGFR mutations (hereafter referred to as EGFR mutations or EGFR-mutated) or any of the follow genomic alterations: ALK gene rearrangements, ROS1 rearrangements, BRAF V600E mutations, NTRK gene fusions, MET exon 14 skipping mutations, RET rearrangements, or less common EGFR point m... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/12/2025

Locations: UCLA Hematology/Oncology - Santa Monica ( Site 0023), Los Angeles, California +189 locations

UCLA Hematology/Oncology - Santa Monica ( Site 0023), Los Angeles, California

Mayo Clinic in Florida-Mayo Clinic Comprehensive Cancer Center ( Site 0001), Jacksonville, Florida

Mid Florida Hematology and Oncology Center ( Site 0005), Orange City, Florida

Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital-Research ( Site 0003), Marietta, Georgia

Karmanos Cancer Institute ( Site 0018), Detroit, Michigan

Mayo Clinic in Rochester, Minnesota-Mayo Clinic Comprehensive Cancer Center ( Site 0027), Rochester, Minnesota

Hattiesburg Clinic Hematology/Oncology ( Site 0010), Hattiesburg, Mississippi

University Of Nebraska Medical Center ( Site 0011), Omaha, Nebraska

Englewood Hospital and Medical Center ( Site 0033), Englewood, New Jersey

Atlantic Health System Morristown Medical Center ( Site 0031), Morristown, New Jersey

Capital Health Medical Center - Hopewell ( Site 0006), Pennington, New Jersey

University of Cincinnati Medical Center-University of Cincinnati Cancer Center ( Site 0015), Cincinnati, Ohio

VCU Health Adult Outpatient Pavillion ( Site 0026), Richmond, Virginia

St. George Private Hospital ( Site 3004), Kogarah, New South Wales

Westmead Hospital ( Site 3000), Westmead, New South Wales

Monash Health-Oncology Research ( Site 3001), Clayton, Victoria

Western Health-Sunshine & Footscray Hospitals-Cancer Services-Cancer Research ( Site 3003), Melbourne, Victoria

Liga Norte Riograndense Contra o Câncer-Centro de Pesquisa Clínica ( Site 0447), Natal, Rio Grande Do Norte

Hospital Nossa Senhora da Conceição-Centro Integrado de Pesquisa em Oncologia ( Site 0440), Porto Alegre, Rio Grande Do Sul

Fundação Pio XII - Hospital de Câncer de Barretos ( Site 0444), Barretos, Sao Paulo

Hospital Paulistano-Americas Oncologia ( Site 0441), Sao Paulo, Not set

A. C. Camargo Cancer Center-CAPEC ( Site 0442), Sao Paulo, Not set

Núcleo de Pesquisa Clínica da Rede São Camilo ( Site 0446), Sao Paulo, Not set

William Osler Health System ( Site 0205), Brampton, Ontario

Princess Margaret Cancer Centre ( Site 0204), Toronto, Ontario

Centro Investigacion Cancer James Lind ( Site 0513), Temuco, Araucania

Clinica Universidad Catolica del Maule-Oncology ( Site 0501), Talca, Maule

Clínica RedSalud Vitacura ( Site 0511), Santiago., Region M. De Santiago

Centro de Estudios Clínicos SAGA ( Site 0517), Santiago, Region M. De Santiago

Orlandi Oncologia-Oncology ( Site 0504), Santiago, Region M. De Santiago

FALP-UIDO ( Site 0509), Santiago, Region M. De Santiago

K2 Oncology ( Site 0514), Santiago, Region M. De Santiago

Pontificia Universidad Catolica de Chile ( Site 0502), Santiago, Region M. De Santiago

Bradfordhill-Clinical Area ( Site 0507), Santiago, Region M. De Santiago

ONCOCENTRO APYS-ACEREY ( Site 0500), Viña del Mar, Valparaiso

Anhui Provincial Cancer Hospital ( Site 2830), Hefei, Anhui

Beijing Cancer hospital-Thoracic Cancer Department A ( Site 2810), Beijing, Beijing

Beijing Peking Union Medical College Hospital-pneumology department ( Site 2815), Beijing, Beijing

Chongqing University Cancer Hospital-Medical Oncology ( Site 2814), Chongqing, Chongqing

Fujian Cancer Hospital ( Site 2819), Fuzhou, Fujian

The First Affiliated hospital of Xiamen University ( Site 2820), Xiamen, Fujian

Southern Medical University Nanfang Hospital-Depatrment of Respiratory and Critical Care Medicine ( Site 2818), Guangzhou, Guangdong

Guangxi Medical University Cancer Hospital-Respiratory Oncology ( Site 2816), Nanning, Guangxi

Harbin Medical University Cancer Hospital-oncology of department ( Site 2807), Harbin, Heilongjiang

Henan Cancer Hospital-henan cancer hospital ( Site 2813), Zhengzhou, Henan

Tongji Hospital Tongji Medical,Science & Technology ( Site 2805), Wuhan, Hubei

Wuhan Union Hospital Cancer Center-Cancer Center ( Site 2806), Wuhan, Hubei

Hubei Cancer Hospital ( Site 2809), Wuhan, Hubei

The Second Xiangya Hospital of Central South University ( Site 2827), Changsha, Hunan

Hunan Cancer Hospital-thoracic oncology II ( Site 2808), Changsha, Hunan

Nanjing Drum Tower Hospital ( Site 2812), Nangjing, Jiangsu

The Second Affiliated Hospital of Nanchang University-Oncology Department ( Site 2821), Nanchang, Jiangxi

Jilin Province Tumor Hospital-clinical research ( Site 2803), Changchun, Jilin

The First Affiliated Hospital of Xi'an Jiaotong University-Oncology ( Site 2817), Xi'an, Shaanxi

Jinan Central Hospital-oncology department ( Site 2802), Jinan, Shandong

LinYi Cancer Hospital ( Site 2804), Linyi, Shandong

Shanghai Chest Hospital-Oncology department ( Site 2800), Shanghai, Shanghai

Fudan University Shanghai Cancer Center-Oncology ( Site 2811), Shanghai, Shanghai

West China Hospital, Sichuan University-Lung cancer center ( Site 2826), Cheng Du, Sichuan

Sichuan Cancer hospital. ( Site 2822), Chengdu, Sichuan

Yunnan Province Cancer Hospital ( Site 2824), Kunming, Yunnan

Sir Run Run Shaw Hospital School of Medicine Zhejiang University ( Site 2828), Hangzhou, Zhejiang

Zhejiang Cancer Hospital ( Site 2829), Hangzhou, Zhejiang

Masarykuv onkologicky ustav-Klinika komplexni onkologicke pece ( Site 1100), Brno, Brno-mesto

Nemocnice AGEL Ostrava - Vitkovice a.s.-Plicni odd ( Site 1103), Ostrava, Ostrava Mesto

Fakultni nemocnice Plzen ( Site 1104), Pilsen, Plzensky Kraj

Fakultni nemocnice Olomouc-Klinika plicnich nemoci a tuberkulozy ( Site 1102), Olomouc, Not set

Vseobecna fakultni nemocnice v Praze-Onkologicka klinika ( Site 1105), Praha 2, Not set

Institut Bergonié - Centre Régional de Lutte Contre Le Cance-Medical Oncology ( Site 1303), Bordeaux, Aquitaine

CHU Charles Nicolle-pneumology, intensive care and thoracic oncology ( Site 1300), Rouen, Haute-Normandie

CENTRE LEON BERARD ( Site 1305), Lyon Cedex08, Rhone-Alpes

Groupe hospitalier Paris saint Joseph. ( Site 1307), Paris, Not set

Institut Curie-Thorax Institute ( Site 1304), Paris, Not set

Universitaetsklinikum Freiburg ( Site 1405), Freiburg, Brandenburg

Universitätsmedizin Göttingen - Georg-August-Universität-Klinik für Hämatologie und Medizinische On ( Site 1407), Goettingen, Niedersachsen

Kliniken Essen-Mitte, Evangelische Huyssens-Stiftung ( Site 1400), Essen, Nordrhein-Westfalen

Klinikum Chemnitz - Flemmingstraße ( Site 1401), Chemnitz, Sachsen

Universitaetsklinikum Carl Gustav Carus Dresden ( Site 1402), Dresden, Sachsen

Asklepios Klinik Harburg ( Site 1403), Hamburg, Not set

Errikos Dunant Hospital Center-Fourth Department of Oncology and Clinical Trials Unit ( Site 2705), Athens, Attiki

THORACIC GENERAL HOSPITAL OF ATHENS "I SOTIRIA"-3rd Dept of Internal Medicine and Laboratory, Oncol ( Site 2700), Athens, Attiki

Aretaieio Hospital ( Site 2702), Athens, Attiki

ATTIKON GENERAL UNIVERSITY HOSPITAL-Oncology ( Site 2704), Chaidari, Athens, Attiki

"Theagenio" Cancer Hospital of Thessaloniki ( Site 2703), Thessaloniki, Kentriki Makedonia

Papageorgiou General Hospital of Thessaloniki ( Site 2701), Thessaloniki, Not set

Hong Kong Integrated Oncology Centre ( Site 3200), Central, Not set

Queen Mary Hospital ( Site 3203), Hksar, Not set

Queen Elizabeth Hospital-Department of Clinical Oncology ( Site 3204), Kowloon, Not set

Princess Margaret Hospital-Department of Oncology ( Site 3201), Lai Chi Kok, Not set

Rambam Health Care Campus-Oncology Division ( Site 1702), Haifa, Not set

Shaare Zedek Medical Center ( Site 1700), Jerusalem, Not set

Rabin Medical Center ( Site 1703), Petah Tikva, Not set

IRCCS - Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori"-Oncologia Medica ( Site 1806), Meldola, Emilia-Romagna

Fondazione Policlinico Universitario Agostino Gemelli IRCCS -Medical Oncology ( Site 1802), Roma, Lazio

Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Oncologia Medica 1 ( Site 1800), Milan, Lombardia

Istituto Clinico Humanitas ( Site 1803), Rozzano, Lombardia

Istituto Nazionale Tumori Regina Elena-Oncologia Medica 2 ( Site 1805), Rome, Roma

Aichi Cancer Center ( Site 3400), Nagoya, Aichi

Fujita Health University Hospital ( Site 3419), Toyoake, Aichi

National Cancer Center Hospital East ( Site 3406), Kashiwa, Chiba

National Hospital Organization Shikoku Cancer Center ( Site 3415), Matsuyama, Ehime

Gunma Prefectural Cancer Center ( Site 3418), Otashi, Gunma

Takarazuka City Hospital ( Site 3409), Takarazuka, Hyogo

Kanazawa University Hospital ( Site 3414), Kanazawa, Ishikawa

Kanagawa Cancer Center ( Site 3404), Yokohama, Kanagawa

Miyagi Cancer Center ( Site 3416), Natori, Miyagi

Sendai Kousei Hospital ( Site 3401), Sendai, Miyagi

Niigata Cancer Center Hospital ( Site 3405), Niigata-shi, Niigata

Kansai Medical University Hospital ( Site 3410), Hirakata, Osaka

Shizuoka Cancer Center ( Site 3403), Nagaizumi-cho,Sunto-gun, Shizuoka

Cancer Institute Hospital of JFCR ( Site 3402), Koto, Tokyo

Chiba University Hospital ( Site 3411), Chiba, Not set

National Hospital Organization Kyushu Medical Center ( Site 3412), Fukuoka, Not set

Kyushu University Hospital ( Site 3407), Fukuoka, Not set

Okayama University Hospital ( Site 3417), Okayama, Not set

Osaka International Cancer Institute ( Site 3413), Osaka, Not set

Nippon Medical School Hospital ( Site 3408), Tokyo, Not set

Chungbuk National University Hospital-Internal medicine ( Site 3809), Cheongju-si, Chungbuk

Chonnam National University Hwasun Hospital-Pulmonology ( Site 3807), Hwasun, Jeonranamdo

National Cancer Center-Lung Cancer Center ( Site 3810), Goyang-si, Kyonggi-do

Seoul National University Bundang Hospital ( Site 3806), Seongnam, Kyonggi-do

The Catholic University Of Korea St. Vincent's Hospital-Medical Oncology ( Site 3803), Suwon-si, Kyonggi-do

Pusan National University Yangsan Hospital-Lung Cancer Clinic ( Site 3811), Yangsan, Kyongsangnam-do

Pusan National University Hospital ( Site 3805), Busan, Pusan-Kwangyokshi

Chungnam national university hospital ( Site 3808), Jung-gu, Taejon-Kwangyokshi

Kangbuk Samsung Hospital ( Site 3813), Seoul, Not set

Severance Hospital, Yonsei University Health System-Lung Cancer Center ( Site 3804), Seoul, Not set

Konkuk University Medical Center ( Site 3812), Seoul, Not set

Asan Medical Center ( Site 3801), Seoul, Not set

Samsung Medical Center-Division of Hematology/Oncology ( Site 3802), Seoul, Not set

Korea University Guro Hospital-Internal Medicine ( Site 3800), Seoul, Not set

Hospital Raja Perempuan Zainab II-Medical Department ( Site 3502), Kota Bharu, Kelantan

National Cancer Institute-Radiotherapy and Oncology ( Site 3504), Putrajaya, Kuala Lumpur

Sarawak General Hospital-Radiotherapy Unit ( Site 3500), Kuching, Sarawak

CIO - Centro de Inmuno-Oncología de Occidente ( Site 0706), Guadalajara, Jalisco

Hospital Universitario "Dr. Jose Eleuterio Gonzalez"-Hematologia and Oncologia ( Site 0704), Monterrey, Nuevo Leon

Centro de Investigacion Clinica de Oaxaca ( Site 0701), Oaxaca de Juarez, Oaxaca

Clinica Integral Internacional de Oncología ( Site 0705), Puebla, Not set

THE MEDICAL CITY ILOILO-The Medical City Iloilo - Clinical and Translational Research Institute-Ilo ( Site 3600), Iloilo City, Iloilo

Manila Doctors Hospital-Clinical Trial Office ( Site 3604), Manila, National Capital Region

Asian Hospital and Medical Center ( Site 3605), Muntinlupa, National Capital Region

THE MEDICAL CITY-Cancer Research Center ( Site 3603), Pasig, National Capital Region

ST. LUKE'S MEDICAL CENTER ( Site 3601), Quezon City, National Capital Region

CARDINAL SANTOS MEDICAL CENTER-Research Room ( Site 3602), San Juan City, Metro Manila, National Capital Region

Centrum Onkologii im. Prof. Franciszka Lukaszczyka-Ambulatorium Chemioterapii ( Site 2003), Bydgoszcz, Kujawsko-pomorskie

Wojewodzki Szpital Zespolony im Ludwika Rydygiera w Toruniu ( Site 2009), Torun, Kujawsko-pomorskie

Instytut Gruźlicy i Chorób Płuc w Warszawie ( Site 2011), Warsaw, Mazowieckie

Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Klinika Nowotworow Pluca i Klatki Pier ( Site 2000), Warszawa, Mazowieckie

Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu ( Site 2001), Przemysl, Podkarpackie

Narodowy Instytut Onkologii - Oddzial w Gliwicach-II Klinika Radioterapi i Chemioterapii ( Site 2002), Gliwice, Slaskie

Swietokrzyskie Centrum Onkologii, Samodzielny Publiczny Zaklad Opieki Zdrowotnej ( Site 2005), Kielce, Swietokrzyskie

HOSPITAL CLÍNIC DE BARCELONA-ICHMO- Clinic Institut of Haematological and Oncological diseases ( Site 2304), Barcelona, Cataluna

Hospital Insular de Gran Canaria-Oncology ( Site 2305), Las Palmas de Gran Canaria, Las Palmas

HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑON-ONCOLOGY ( Site 2303), Madrid, Madrid, Comunidad De

HOSPITAL UNIVERSITARIO QUIRONSALUD MADRID-ONCOLOGIA MEDICA ( Site 2301), Pozuelo de Alarcon, Madrid

H.R.U Málaga - Hospital General-Oncology ( Site 2302), Málaga, Malaga

Hospital Universitari Vall d'Hebron-Departamento de Oncologia- VHIO ( Site 2300), Barcelona, Not set

Clinica Universidad de Navarra-Medical Oncology ( Site 2306), Madrid, Not set

Chi Mei Medical Center ( Site 3910), Tainan City, Tainan

National Taiwan University Cancer Center (NTUCC) ( Site 3903), Taipei City, Taipei

Changhua Christian Hospital ( Site 3908), Changhua, Not set

National Taiwan University Hospital - Hsinchu branch ( Site 3907), Hsinchu, Not set

Kaohsiung Medical University Chung-Ho Memorial Hospital ( Site 3912), Kaohsiung, Not set

E-Da hospital ( Site 3911), Kaohsiung, Not set

Chang Gung Memorial Hospital at Kaohsiung ( Site 3906), Kaohsiung, Not set

National Cheng Kung University Hospital ( Site 3909), Tainan, Not set

National Taiwan University Hospital-Oncology ( Site 3904), Taipei, Not set

Mackay Memorial Hospital-Chest Medicine ( Site 3902), Taipei, Not set

Taipei Medical University Hospital ( Site 3900), Taipei, Not set

Maharaj Nakorn Chiang Mai Hospital ( Site 4003), Muang, Chiang Mai

Faculty of Medicine Siriraj Hospital ( Site 4000), Bangkok, Krung Thep Maha Nakhon

Lampang Cancer Hospital ( Site 4005), Muang, Lampang

Songklanagarind hospital ( Site 4001), HatYai, Songkhla

Faculty of Medicine - Khon Kaen University ( Site 4004), Khon Kaen, Not set

Sunpasitthiprasong Hospital-Oncology ( Site 4002), Ubon Ratchathani, Not set

Medipol Mega Universite Hastanesi-oncology ( Site 2505), Stanbul, Istanbul

Ege Universitesi Hastanesi-Chest Diseases Department ( Site 2504), Bornova, Izmir

Adana Medical Park Seyhan Hastanesi ( Site 2506), Adana, Not set

Hacettepe Universite Hastaneleri-oncology hospital ( Site 2500), Ankara, Not set

Ankara Bilkent Şehir Hastanesi-Medical Oncology ( Site 2501), Ankara, Not set

TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 2502), Istanbul, Not set

ROYAL MARSDEN HOSPITAL (CHELSEA) ( Site 2606), London, Kensington And Chelsea

St Bartholomew's Hospital-Centre for Experimental Cancer Medicine ( Site 2600), London, London, City Of

Guy's & St Thomas' NHS Foundation Trust-Oncology & Haematology Clinical Trials ( Site 2603), London, London, City Of

Royal Marsden Hospital (Sutton) ( Site 2605), Sutton., Surrey

The Christie NHS Foundation Trust ( Site 2604), Manchester, Not set

The Clatterbridge Cancer Centre ( Site 2602), Wirral, Not set

Hanoi Oncology Hospital ( Site 4102), Hanoi, Ha Noi

K Hospital - National Cancer Hospital ( Site 4105), Hanoi, Ha Noi

National Lung Hospital-Oncology Department ( Site 4104), Hanoi, Ha Noi

Conditions: Non-small Cell Lung Cancer (NSCLC)

Learn More ›

A Study to Evaluate the Efficacy and Safety of Frexalimab, SAR442970, or Rilzabrutinib in Participants Aged 16 to 75 Years With Primary Focal Segmental Glomerulosclerosis or Minimal Change Disease

NCT06500702

Recruiting

This is a parallel, Phase 2a, double-blind, 6-arm study for the treatment of primary focal segmental glomerulosclerosis (FSGS) or primary minimal change disease (MCD). The purpose of this study is to measure the change in proteinuria and its impact on the rates of remission of nephrotic syndrome with frexalimab, SAR442970, or rilzabrutinib compared with placebo in participants with primary FSGS or primary MCD aged 16 to 75 years. Study details for each participant include: The study duration... Read More

Gender:

ALL

Ages:

Between 16 years and 75 years

Trial Updated:

08/12/2025

Locations: Investigational Site Number: 8400007, Birmingham, Alabama +57 locations

Investigational Site Number: 8400007, Birmingham, Alabama

Investigational Site Number : 8400015, Orange, California

Investigational Site Number : 8400012, San Francisco, California

Investigational Site Number : 8400014, Chicago, Illinois

Investigational Site Number : 8400017, Hinsdale, Illinois

Investigational Site Number : 8400010, Ann Arbor, Michigan

Investigational Site Number : 8400019, Edina, Minnesota

Investigational Site Number : 8400018, Las Vegas, Nevada

Investigational Site Number : 8400001, New York, New York

Investigational Site Number : 8400021, Chapel Hill, North Carolina

Investigational Site Number : 8400005, El Paso, Texas

Investigational Site Number: 8400016, Houston, Texas

Investigational Site Number : 0320002, Cordoba, Córdoba

Investigational Site Number : 0320001, Buenos Aires, Not set

Investigational Site Number : 0360003, Canberra, Australian Capital Territory

Investigational Site Number : 0360001, Parkville, Victoria

Investigational Site Number : 0760002, Sao Paulo, São Paulo

Investigational Site Number: 0760001, São Paulo, Not set

Investigational Site Number : 1240002, London, Ontario

Investigational Site Number : 1240001, Montreal, Quebec

Investigational Site Number : 1240006, Quebec City, Quebec

Investigational Site Number : 1520002, Santiago, Reg Metropolitana De Santiago

Investigational Site Number : 1520003, Temuco, Not set

Investigational Site Number : 1560001, Beijing, Not set

Investigational Site Number : 1560003, Chengdu, Not set

Investigational Site Number : 1560004, Shanghai, Not set

Investigational Site Number : 2030002, Olomouc, Not set

Investigational Site Number : 2030001, Prague, Not set

Investigational Site Number : 2500002, Créteil, Not set

Investigational Site Number : 2500001, Paris, Not set

Investigational Site Number : 2760002, Berlin, Not set

Investigational Site Number : 2760003, Hannover, Not set

Investigational Site Number : 3000002, Athens, Not set

Investigational Site Number : 3000001, Heraklion, Not set

Investigational Site Number : 3480001, Budapest, Not set

Investigational Site Number : 3800002, Florence, Firenze

Investigational Site Number : 3800003, Naples, Napoli

Investigational Site Number : 3800001, Brescia, Not set

Investigational Site Number : 4840001, Mexico City, Ciudad De Mexico

Investigational Site Number : 4840003, Monterrey, Nuevo León

Investigational Site Number : 5280001, Amsterdam, Not set

Investigational Site Number : 6160002, Opole, Not set

Investigational Site Number : 6200001, Matosinhos, Not set

Investigational Site Number : 6200002, Porto, Not set

Investigational Site Number : 7030003, Banská Bystrica, Not set

Investigational Site Number : 7030001, Martin, Not set

Investigational Site Number : 7240001, Barcelona, Barcelona [Barcelona]

Investigational Site Number : 7240004, Barcelona, Catalunya [Cataluña]

Investigational Site Number : 7240005, Seville, Sevilla

Investigational Site Number : 7240002, Córdoba, Not set

Investigational Site Number : 7240003, Valencia, Not set

Investigational Site Number : 1580001, Taichung, Not set

Investigational Site Number : 1580002, Taipei City, Not set

Investigational Site Number : 7920001, Izmit, Not set

Investigational Site Number : 7920002, Kayseri, Not set

Investigational Site Number : 8260001, Leicester, Leicestershire

Investigational Site Number : 8260004, Salford, Manchester

Investigational Site Number : 8260005, Oxford, Oxfordshire

Conditions: Focal Segmental Glomerulosclerosis, Glomerulonephritis Minimal Lesion

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Hypertonic Saline for MAC

NCT04921943

Recruiting

The MAC-HS study is a testing whether hypertonic saline helps improve symptoms and clearance of mycobacteria in patients with M. avium complex lung infections.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/12/2025

Locations: NYU Langone Health, New York, New York +2 locations

Conditions: Nontuberculous Mycobacterial Lung Disease, Nontuberculous Mycobacterium Infection

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