All Clinical Trials in Canada

A listing of 3904 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

Home

Canada

Show Filters

Match to Clinical Trials

Access to cutting-edge treatments

Latest clinical trials

Find trials in your area

Start Matching

Filter by Age

Observational Study of Oral Atogepant to Evaluate Real-World Effectiveness in Adult Participants With Migraine

NCT06543914

Recruiting

Migraine is a neurological disease characterized by moderate or severe headache, associated with nausea, vomiting, and/or sensitivity to light and sound. This study will evaluate the effectiveness of atogepant in treating adult participants with migraine in a real-world setting. Atogepant is an approved drug for preventive treatment of migraine in adults. Approximately 1000 adult participants who are prescribed atogepant by their doctors will be enrolled in this study across the world. Partici... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/12/2025

Locations: Neurology and Neurodiagnostics of Alabama /ID# 267614, Hoover, Alabama +79 locations

Neurology and Neurodiagnostics of Alabama /ID# 267614, Hoover, Alabama

Barrow Neurological Institute - Dignity Health St. Joseph's Hosp and Medical Ctr /ID# 267610, Phoenix, Arizona

Kenneth Martinez MD, A Medical Corp /ID# 267834, Aliso Viejo, California

Los Angeles Headache Center /ID# 267570, Los Angeles, California

Alcanza Clinical Research, LLC /ID# 267838, Lake Mary, Florida

Norton Cancer Institute - St. Matthews /ID# 267605, Louisville, Kentucky

Dent Neurologic Institute - Amherst /ID# 267606, Amherst, New York

Grace Forde /ID# 267596, N. New Hyde Park, New York

Thomas Jefferson University Hospital /ID# 267572, Philadelphia, Pennsylvania

Inova Health Care System /ID# 267615, Falls Church, Virginia

Neuroscience Group /ID# 267571, Neenah, Wisconsin

Cliniques Universitaires UCL Saint-Luc /ID# 270545, Bruxelles, Bruxelles-Capitale

Universitair Ziekenhuis Brussel /ID# 269799, Jette, Bruxelles-Capitale

Chu Tivoli /ID# 271254, La Louvière, Hainaut

Centre Hospitalier Régional de la Citadelle /ID# 270539, Liège, Liege

Groupe Sante CHC - Clinique du MontLegia /ID# 270218, Liège, Liege

OLV Ziekenhuis Aalst /ID# 270284, Aalst, Oost-Vlaanderen

AZ Sint-Jan Brugge /ID# 270540, Brugge, West-Vlaanderen

AZ Groeninge /ID# 272772, Kortrijk, West-Vlaanderen

Calgary Headache Assessment and Management Program /ID# 270266, Calgary, Alberta

Burrard Health Center /ID# 270268, Vancouver, British Columbia

Dr. Renju Kuriakose Prof. Corp. /ID# 273178, Saint John, New Brunswick

Maritime Neurology /ID# 270270, Halifax, Nova Scotia

Centricity /ID# 271478, London, Ontario

Bayshore Neurology /ID# 270673, Ottawa, Ontario

Sunnybrook Health Sciences Centre /ID# 273207, Toronto, Ontario

Centre de Recherche St-Louis /ID# 270957, Lévis, Quebec

Genge Partners /ID# 270267, Montreal, Quebec

Universitaetsklinikum Heidelberg /ID# 278134, Heidelberg, Baden-Wuerttemberg

Praxis fur Neurologie Dr. med. Martin Delf /ID# 275918, Hoppegarten, Brandenburg

Zentrum Für Klinische Forschung Dr. Irma Schöll /ID# 275642, Bad Homburg, Hessen

Universitaetsmedizin Greifswald /ID# 276678, Greifswald, Mecklenburg-Vorpommern

ZNS Siegen /ID# 275660, Siegen, Nordrhein-Westfalen

Schmerzklinik Kiel /ID# 275592, Kiel, Schleswig-Holstein

Charite Universitaetsmedizin Berlin - Campus Mitte /ID# 275760, Berlin, Not set

Schmerzzentrum Berlin /ID# 275819, Berlin, Not set

Neurologischen Facharztzentrum Berlin /ID# 275919, Berlin, Not set

Städtisches Klinikum Brandenburg /ID# 275725, Brandenburg, Not set

IRCCS Ospedale San Raffaele /ID# 273153, Milan, Milano

Sapienza University of Rome /ID# 273506, Rome, Roma

Azienda Ospedaliero Universitaria delle Marche /ID# 273349, Ancona, Not set

Fondazione Mondino Istituto Neurologico Nazionale a Carattere Scientifico IRCCS /ID# 273155, Pavia, Not set

Gelre Ziekenhuis /ID# 272429, Apeldoorn, Gelderland

Zaans Medisch Centrum /ID# 269603, Zaandam, Noord-Holland

Isala, locatie Zwolle /ID# 269602, Zwolle, Overijssel

Maasstad Ziekenhuis /ID# 269601, Rotterdam, Zuid-Holland

Hodeverket /ID# 271383, Sandnes, Rogaland

Oslo Hodepinesenter AS /ID# 271384, Oslo, Not set

Hospital da Luz /ID# 267002, Lisbon, Lisboa

CUF Sintra Hospital /ID# 272394, Sintra, Lisboa

Campus Neurológico Sénior /ID# 272392, Torres Vedras, Lisboa

Hospital CUF Porto /ID# 272788, Porto, Not set

Hospital Regional Universitario de Malaga /ID# 268272, Malaga, Andalucia

Hospital Universitario Severo Ochoa /ID# 268249, Leganés, Madrid

Hospital Universitario Puerta de Hierro - Majadahonda /ID# 268246, Majadahonda, Madrid

Hospital Universitario Virgen Macarena /ID# 268244, Seville, Sevilla

Hospital Universitario Vall d'Hebron /ID# 268222, Barcelona, Not set

Hospital Universitario de La Princesa /ID# 268245, Madrid, Not set

Hospital Universitario La Paz /ID# 268238, Madrid, Not set

Hospital Universitario Virgen del Rocio /ID# 268223, Sevilla, Not set

Hospital Clinico Universitario de Valladolid /ID# 268225, Valladolid, Not set

Hospital Clinico Universitario Lozano Blesa /ID# 268243, Zaragoza, Not set

Karolinska Universitetssjukhuset - Huddinge /ID# 265295, Huddinge, Stockholms Lan

Neurology Clinic /ID# 266707, Stockholm, Stockholms Lan

Skaneuro /ID# 265203, Lund, Not set

ZURZACH Care /ID# 265697, Bad Zurzach, Aargau

NeuroPraxis Birseck /ID# 266140, Reinach BL, Basel-Landschaft

DYA Swiss Institut SA /ID# 266891, Lugano, Ticino

EOC Ospedale Regionale Lugano /ID# 266887, Lugano, Ticino

CHUV, Centre hospitalier universitaire vaudois /ID# 266551, Lausanne, Vaud

Kopfwehzentrum Hirslanden Zuerich /ID# 265817, Zollikon, Zuerich

Inselspital, Universitaetsspital Bern /ID# 265818, Bern, Not set

Tri-Service General Hospital /ID# 272082, Taipei, Not set

Linkou Chang Gung Memorial Hospital /ID# 272084, Taoyuan City, Not set

Hull Royal Infirmary /ID# 276819, Hull, East Riding Of Yorkshire

Western General Hospital - NHS Lothian /ID# 277029, Edinburgh, Edinburgh, City Of

Cripps Health Centre /ID# 277474, Nottingham, Nottinghamshire

Great Western Hospital /ID# 276693, Swindon, Wiltshire

Worcestershire Royal Hospital /ID# 276902, Worcester, Worcestershire

Ulster Hospital - South Eastern Health & Social Care Trust /ID# 276900, Belfast, Not set

Conditions: Migraine

Learn More ›

Akkermansia Muciniphilia and Metabolic Side Effects of ADT

NCT05802121

Recruiting

The overriding objectives of this study are: 1. Primary outcomes: 1. To confirm that administration of oral acetate increases the proportion of A. muciniphilia in the stool samples of patients with metastatic, castration-sensitive prostate cancer compared to placebo. 2. To confirm tolerability and assess for side effects of delayed oral acetate supplementation. 2. Secondary outcomes: 1. To determine if increased counts of A. muciniphilia correlate with improved metabolic parameters a... Read More

Gender:

MALE

Ages:

18 years and above

Trial Updated:

08/12/2025

Locations: London Health Sciences Centre - Victoria Hospital, London, Ontario

Conditions: Prostate Cancer, Metabolic Syndrome, Obesity, Cardiovascular Morbidity, Bone Diseases, Hyperlipidemias, Diabetes

Learn More ›

A Long-term Safety and Efficacy Study Evaluating APG777 in Atopic Dermatitis

NCT07003425

Recruiting

This is a multicenter, double-blind, Long-Term Extension (LTE) study to evaluate the long-term safety and efficacy of APG777 in patients with moderate-to-severe AD who have completed treatment in an APG777 Parent Study (NCT06395948). The LTE study will consist of 3 periods: 1) Screening Visit will coincide with the last visit of the Maintenance Period in the Parent Study 2) Extended Treatment Period 3) Post-treatment Follow-up Period. This study will be conducted in participants with atopic de... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/12/2025

Locations: Investigational Site, Fountain Valley, California +31 locations

Investigational Site, Fountain Valley, California

Investigational Site, Coral Gables, Florida

Investigational Site, Margate, Florida

Investigational Site, Detroit, Michigan

Investigational Site, Troy, Michigan

Investigational Site, Wilmington, North Carolina

Investigational Site, Boardman, Ohio

Investigational Site, Mason, Ohio

Investigational Site, Portland, Oregon

Investigational Site, Nashville, Tennessee

Investigational Site, Frisco, Texas

Investigational Site, San Antonio, Texas

Investigational Site, Calgary, Alberta

Investigational Site, Edmonton, Alberta

Investigational Site, Fredericton, Brunswick

Investigational Site, Markham, Ontario

Investigational Site, Mississauga, Ontario

Investigational Site, Peterborough, Ontario

Investigational Site, Toronto, Ontario

Investigational Site, Montréal, Quebec

Investigational Site, Quebec City, Quebec

Investigational Site, Wrocław, Dolnoslaskie

Investigational Site, Wrocław, Dolnośląskie

Investigational Site, Lublin, Lubelskie

Investigational Site, Warszawa, Mazowieckie

Investigational Site, Gdańsk, Pomorskie

Investigational Site, Katowice, Silesia

Investigational Site, Sosnowiec, Silesia

Investigational Site, Kraków, Woj. Małopolskie

Investigational Site, Łódź, Not set

Conditions: Atopic Dermatitis

Learn More ›

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

NCT06819891

Recruiting

This Phase III, multicenter, double-blind, placebo-controlled study will evaluate the efficacy and safety of induction therapy with Afimkibart (also known as RO7790121) in participants with moderately to severely active Crohn's disease (CD).

Gender:

ALL

Ages:

Between 16 years and 80 years

Trial Updated:

08/12/2025

Locations: Om Research LLC, Lancaster, California +89 locations

Om Research LLC, Lancaster, California

Amicis Research Center, Santa Clarita, California

Peak Gastroenterology Associates, Colorado Springs, Colorado

J&A Clinical Research, Doral, Florida

Miami Beach Clinical Research Center, Miami Beach, Florida

Homestead Associates in Research, Inc., Miami, Florida

Allied Biomedical Research Institute, Inc, Miami, Florida

Eminat Research Group, Miramar, Florida

Digestive and Liver Center of Florida, Orlando, Florida

Advanced Medical Research Center, Port Orange, Florida

Louisiana Research Center - GastroIntestinal Associates, Shreveport, Louisiana

Mercy Medical Center, Baltimore, Maryland

Chevy Chase Clinical Research, Chevy Chase, Maryland

Gastroenterology Associates of Western Michigan, P.L.C., Wyoming, Michigan

Ellipsis Research Group, Brooklyn, New York

Intercity Gastroenterology, Fresh Meadows, New York

Charlotte Gastroenterology and Hepatology, P.L.L.C, Charlotte, North Carolina

Clinical Inquest Center, Beavercreek, Ohio

GI Alliance, Garland, Texas

Carta - Clinical Associates In Research Therapeutics Of America;LLC, San Antonio, Texas

University of Texas Health Center at Tyler, Tyler, Texas

CICE 9 de Julio, San Miguel de Tucumán, Not set

Macquarie University Hospital, Macquarie Park, New South Wales

Coral Sea Clinical Research Institute, Mackay, Queensland

Royal Melbourne Hospital, Parkville, Victoria

Ordensklinikum Linz Barmherzige Schwestern, Linz, Not set

Klinikum Wels-Grieskirchen, Wels, Not set

CHU St Pierre (St Pierre), Brussels, Not set

UZ Brussel, Brussel, Not set

Cliniques Universitaires St-Luc, Bruxelles, Not set

Instituto Lobus Unimed Volta Redonda, Volta Redonda, Rio De Janeiro

Hospital Moinhos de Vento, Porto Alegre, Rio Grande Do Sul

CECIP - Centro de Estudos Clínicos do Interior Paulista, Jaú, São Paulo

Hospital de Base de Sao Jose do Rio Preto, Sao Jose do Rio Preto, São Paulo

Barrie GI Associates, Barrie, Ontario

London Health Sciences Centre Uni Campus, London, Ontario

Toronto Immune and Digestive Health Institute, North York, Ontario

Centro de Investigación Clínica UC-CICUC, Santiago, Not set

First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi

The First Affilliated Hospital of Kunming Medical University, Kunming, Yunnan

Jinhua municipal central hospital, Jinhua, Zhejiang

Beijing Union Hospital, Beijing, Not set

Sichuan Provincial People's Hospital, Chengdu, Not set

Guangzhou First People's Hospital, Guangzhou, Not set

Zhujiang Hospital, Southern Medical University, Guangzhou, Not set

Hainan General Hospital, Haikou, Not set

Huizhou First Hospital, Huizhou, Not set

The Second Affiliated Hospital of Nanchang University, Nanchang City, Not set

Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, Not set

Shengjing Hospital of China Medical University, ShenYang, Not set

Hebei Medical University - The Second Hospital, Shijiazhuang City, Not set

The Second Affiliated Hospital of Xi'an Jiao Tong University, Xi'an City, Not set

Affiliated Hospital of Jiangsu University, Zhenjiang, Not set

Hospital Universitario San Ignacio, Bogota, Not set

Clínica de la Mujer, Bogotá, Not set

Oncomedica S.A., Monteria, Not set

Hepato-Gastroenterologie HK, s.r.o., Hradec Kralove, Not set

Fakultni nemocnice Ostrava, Ostrava - Poruba, Not set

ISCARE a.s., Praha 7, Not set

CHU Tours - Hôpital Trousseau, Chambray les Tours, Not set

CHU Clermont Ferrand - Hôpital d'Estaing, Clermont Ferrand, Not set

Hôpital Henri Mondor, Créteil, Not set

CH Dptal Les Oudairies, La Roche Sur Yon, Not set

CHRU de Lille - Hopital Claude Huriez, Lille, Not set

Hopital Dupuytren, Limoges, Not set

Hopital Saint-Eloi, Montpellier, Not set

Institut des MICI, Clinique Ambroise Paré, Neuilly sur Seine, Not set

Hôpital Saint-Louis, Paris, Not set

Centre Hospitalier Lyon Sud, Pierre-Benite, Not set

Hôpital de Brabois Adultes, Vandoeuvre-les-nancy, Not set

Semmelweis Egyetem, Budapest, Not set

Vas-Oxy Egeszsegugyi Kft, Szombathely, Not set

Policlinico Universitario Campus Biomedico Di Roma, Roma, Lazio

Policlinico Universitario Agostino Gemelli, Roma, Lazio

Medical Center Kermed, Bydgoszcz, Not set

MZ Badania Slowik Zymla Sp.j., Knurów, Not set

Centrum Medyczne Promed, Kraków, Not set

Medrise sp z o.o, Lublin, Not set

Gabinety Lekarskie Rivermed, Pozna?, Not set

Clinical Research Center Sp. z o.o. MEDIC-R Spó?ka Komandytowa, Pozna?, Not set

Endoskopia Sp. z o.o., Sopot, Not set

Centrum Zdrowia-MDM, Warszawa, Not set

PlanetMed sp. z o.o., Wroc?aw, Not set

Hospital de Braga, Braga, Not set

Hospital de Santa Maria, Lisboa, Not set

Hospital de Sao Joao, Porto, Not set

Hospital Clinico Univ. Lozano Blesa, Zaragoza, Not set

Fairfield General Hospital, Bury, Not set

Bronglais General Hospital, Llanrhystud, Not set

Royal London Hospital, London, Not set

Conditions: Moderately to Severely Active Crohns Disease

Learn More ›

Daptomycin vs. Vancomycin for the Treatment of Methicillin Resistant S. Aureus Bacteremia

NCT06637332

Recruiting

This is an open label randomized controlled trial for patients with methicillin resistant S. aureus (MRSA) bloodstream infection which will directly compare the two most commonly used therapies, vancomycin and daptomycin. This study is an approved sub-study of The Staphylococcus aureus Network Adaptive Platform (SNAP) trial (NCT05137119)

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/12/2025

Locations: Concord Repatriation and General Hospital, Concord, New South Wales +12 locations

Conditions: Staphylococcus Aureus Septicemia, Staphylococcus Aureus Bacteremia, S. Aureus Bacteremia, S. Aureus Bloodstream Infection, Staphylococcus Aureus Endocarditis

Learn More ›

A Study to Evaluate the Efficacy and Safety of Frexalimab, SAR442970, or Rilzabrutinib in Participants Aged 16 to 75 Years With Primary Focal Segmental Glomerulosclerosis or Minimal Change Disease

NCT06500702

Recruiting

This is a parallel, Phase 2a, double-blind, 6-arm study for the treatment of primary focal segmental glomerulosclerosis (FSGS) or primary minimal change disease (MCD). The purpose of this study is to measure the change in proteinuria and its impact on the rates of remission of nephrotic syndrome with frexalimab, SAR442970, or rilzabrutinib compared with placebo in participants with primary FSGS or primary MCD aged 16 to 75 years. Study details for each participant include: The study duration... Read More

Gender:

ALL

Ages:

Between 16 years and 75 years

Trial Updated:

08/12/2025

Locations: Investigational Site Number: 8400007, Birmingham, Alabama +57 locations

Investigational Site Number: 8400007, Birmingham, Alabama

Investigational Site Number : 8400015, Orange, California

Investigational Site Number : 8400012, San Francisco, California

Investigational Site Number : 8400014, Chicago, Illinois

Investigational Site Number : 8400017, Hinsdale, Illinois

Investigational Site Number : 8400010, Ann Arbor, Michigan

Investigational Site Number : 8400019, Edina, Minnesota

Investigational Site Number : 8400018, Las Vegas, Nevada

Investigational Site Number : 8400001, New York, New York

Investigational Site Number : 8400021, Chapel Hill, North Carolina

Investigational Site Number : 8400005, El Paso, Texas

Investigational Site Number: 8400016, Houston, Texas

Investigational Site Number : 0320002, Cordoba, Córdoba

Investigational Site Number : 0320001, Buenos Aires, Not set

Investigational Site Number : 0360003, Canberra, Australian Capital Territory

Investigational Site Number : 0360001, Parkville, Victoria

Investigational Site Number : 0760002, Sao Paulo, São Paulo

Investigational Site Number: 0760001, São Paulo, Not set

Investigational Site Number : 1240002, London, Ontario

Investigational Site Number : 1240001, Montreal, Quebec

Investigational Site Number : 1240006, Quebec City, Quebec

Investigational Site Number : 1520002, Santiago, Reg Metropolitana De Santiago

Investigational Site Number : 1520003, Temuco, Not set

Investigational Site Number : 1560001, Beijing, Not set

Investigational Site Number : 1560003, Chengdu, Not set

Investigational Site Number : 1560004, Shanghai, Not set

Investigational Site Number : 2030002, Olomouc, Not set

Investigational Site Number : 2030001, Prague, Not set

Investigational Site Number : 2500002, Créteil, Not set

Investigational Site Number : 2500001, Paris, Not set

Investigational Site Number : 2760002, Berlin, Not set

Investigational Site Number : 2760003, Hannover, Not set

Investigational Site Number : 3000002, Athens, Not set

Investigational Site Number : 3000001, Heraklion, Not set

Investigational Site Number : 3480001, Budapest, Not set

Investigational Site Number : 3800002, Florence, Firenze

Investigational Site Number : 3800003, Naples, Napoli

Investigational Site Number : 3800001, Brescia, Not set

Investigational Site Number : 4840001, Mexico City, Ciudad De Mexico

Investigational Site Number : 4840003, Monterrey, Nuevo León

Investigational Site Number : 5280001, Amsterdam, Not set

Investigational Site Number : 6160002, Opole, Not set

Investigational Site Number : 6200001, Matosinhos, Not set

Investigational Site Number : 6200002, Porto, Not set

Investigational Site Number : 7030003, Banská Bystrica, Not set

Investigational Site Number : 7030001, Martin, Not set

Investigational Site Number : 7240001, Barcelona, Barcelona [Barcelona]

Investigational Site Number : 7240004, Barcelona, Catalunya [Cataluña]

Investigational Site Number : 7240005, Seville, Sevilla

Investigational Site Number : 7240002, Córdoba, Not set

Investigational Site Number : 7240003, Valencia, Not set

Investigational Site Number : 1580001, Taichung, Not set

Investigational Site Number : 1580002, Taipei City, Not set

Investigational Site Number : 7920001, Izmit, Not set

Investigational Site Number : 7920002, Kayseri, Not set

Investigational Site Number : 8260001, Leicester, Leicestershire

Investigational Site Number : 8260004, Salford, Manchester

Investigational Site Number : 8260005, Oxford, Oxfordshire

Conditions: Focal Segmental Glomerulosclerosis, Glomerulonephritis Minimal Lesion

Learn More ›

Testing the Addition of BMS-986016 (Relatlimab) to the Usual Immunotherapy After Initial Treatment for Recurrent or Metastatic Nasopharyngeal Cancer

NCT06029270

Recruiting

This phase II trial tests the addition of BMS-986016 (relatlimab) to the usual immunotherapy after initial treatment for nasopharyngeal cancer that has come back after a period of improvement (recurrent) or that has spread from where it first started (primary site) to other places in the body (metastatic). Relatlimab is a monoclonal antibody that may interfere with the ability of tumor cells to grow and spread. The usual approach of treatment is initial treatment with chemotherapy such as the co... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/12/2025

Locations: Kaiser Permanente Dublin, Dublin, California +72 locations

Kaiser Permanente Dublin, Dublin, California

Kaiser Permanente-Fremont, Fremont, California

Kaiser Permanente-Fresno, Fresno, California

Keck Medicine of USC Koreatown, Los Angeles, California

Los Angeles General Medical Center, Los Angeles, California

USC / Norris Comprehensive Cancer Center, Los Angeles, California

Kaiser Permanente-Modesto, Modesto, California

USC Norris Oncology/Hematology-Newport Beach, Newport Beach, California

Kaiser Permanente-Oakland, Oakland, California

Stanford Cancer Institute Palo Alto, Palo Alto, California

Kaiser Permanente-Roseville, Roseville, California

Kaiser Permanente Downtown Commons, Sacramento, California

University of California Davis Comprehensive Cancer Center, Sacramento, California

Kaiser Permanente-South Sacramento, Sacramento, California

Kaiser Permanente-San Francisco, San Francisco, California

Kaiser Permanente-Santa Teresa-San Jose, San Jose, California

Kaiser Permanente San Leandro, San Leandro, California

Kaiser San Rafael-Gallinas, San Rafael, California

Kaiser Permanente Medical Center - Santa Clara, Santa Clara, California

Kaiser Permanente-Santa Rosa, Santa Rosa, California

Kaiser Permanente-South San Francisco, South San Francisco, California

Kaiser Permanente-Vallejo, Vallejo, California

Kaiser Permanente-Walnut Creek, Walnut Creek, California

Emory University Hospital Midtown, Atlanta, Georgia

Kaiser Permanente Moanalua Medical Center, Honolulu, Hawaii

Saint Alphonsus Cancer Care Center-Boise, Boise, Idaho

Saint Alphonsus Cancer Care Center-Caldwell, Caldwell, Idaho

Kootenai Health - Coeur d'Alene, Coeur d'Alene, Idaho

Saint Alphonsus Cancer Care Center-Nampa, Nampa, Idaho

Kootenai Clinic Cancer Services - Post Falls, Post Falls, Idaho

Kootenai Clinic Cancer Services - Sandpoint, Sandpoint, Idaho

Northwestern University, Chicago, Illinois

University of Illinois, Chicago, Illinois

Carle at The Riverfront, Danville, Illinois

Northwestern Medicine Cancer Center Kishwaukee, DeKalb, Illinois

Carle Physician Group-Effingham, Effingham, Illinois

Northwestern Medicine Cancer Center Delnor, Geneva, Illinois

Northwestern Medicine Glenview Outpatient Center, Glenview, Illinois

Northwestern Medicine Grayslake Outpatient Center, Grayslake, Illinois

Northwestern Medicine Lake Forest Hospital, Lake Forest, Illinois

Carle Physician Group-Mattoon/Charleston, Mattoon, Illinois

Northwestern Medicine Orland Park, Orland Park, Illinois

Carle Cancer Center, Urbana, Illinois

Northwestern Medicine Cancer Center Warrenville, Warrenville, Illinois

Heartland Oncology and Hematology LLP, Council Bluffs, Iowa

Methodist Jennie Edmundson Hospital, Council Bluffs, Iowa

Nebraska Cancer Specialists/Oncology Hematology West PC - MEJ, Council Bluffs, Iowa

Mercy Hospital South, Saint Louis, Missouri

Mercy Hospital Saint Louis, Saint Louis, Missouri

Community Hospital of Anaconda, Anaconda, Montana

Billings Clinic Cancer Center, Billings, Montana

Bozeman Health Deaconess Hospital, Bozeman, Montana

Benefis Sletten Cancer Institute, Great Falls, Montana

Logan Health Medical Center, Kalispell, Montana

Community Medical Center, Missoula, Montana

Nebraska Cancer Specialists/Oncology Hematology West PC - MECC, Omaha, Nebraska

Nebraska Methodist Hospital, Omaha, Nebraska

Oncology Associates PC, Omaha, Nebraska

University of Cincinnati Cancer Center-UC Medical Center, Cincinnati, Ohio

University of Cincinnati Cancer Center-West Chester, West Chester, Ohio

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Oklahoma Cancer Specialists and Research Institute-Tulsa, Tulsa, Oklahoma

Saint Alphonsus Cancer Care Center-Ontario, Ontario, Oregon

Providence Portland Medical Center, Portland, Oregon

Providence Saint Vincent Medical Center, Portland, Oregon

ProHealth D N Greenwald Center, Mukwonago, Wisconsin

ProHealth Oconomowoc Memorial Hospital, Oconomowoc, Wisconsin

ProHealth Waukesha Memorial Hospital, Waukesha, Wisconsin

UW Cancer Center at ProHealth Care, Waukesha, Wisconsin

University Health Network-Princess Margaret Hospital, Toronto, Ontario

Chinese University of Hong Kong-Prince of Wales Hospital, Shatin, Not set

National University Hospital Singapore, Singapore, Not set

National Cancer Centre Singapore, Singapore, Not set

Conditions: Metastatic Nasopharyngeal Carcinoma, Recurrent Nasopharyngeal Carcinoma, Stage IV Nasopharyngeal Carcinoma AJCC v8

Learn More ›

Evaluation of Oral Tofacitinib in Children Aged 2 to 17 Years Old Suffering From Moderate to Severe Ulcerative Colitis

NCT04624230

Recruiting

This study, A3921210 is designed to evaluate the efficacy, safety and pharmacokinetics (PK) of tofacitinib in pediatric participants with moderately to severely active UC. In the US and EU, patients with prior TNFi failure or intolerance will be enrolled. Outside of the US or EU, patients having had inadequate response or intolerance to oral or IV corticosteroids or azathioprine or 6-mercaptopurine or TNFi will be enrolled. All eligible participants will initially receive open label tofacitinib... Read More

Gender:

ALL

Ages:

Between 2 years and 17 years

Trial Updated:

08/12/2025

Locations: Children's Hospital Los Angeles, Los Angeles, California +76 locations

Children's Hospital Los Angeles, Los Angeles, California

University of California, San Francisco Benioff Children's Hospital, San Francisco, California

University of California, San Francisco Pediatric Clinical Research Center (PCRC), San Francisco, California

Connecticut Children's Ambulatory Surgical Center, Farmington, Connecticut

Connecticut Children's Infusion Center, Farmington, Connecticut

Connecticut Children's Medical Center, Hartford, Connecticut

Nicklaus Children's Hospital, Miami, Florida

Center for Advanced Pediatrics, Atlanta, Georgia

Children's Healthcare of Atlanta - Arthur M. Blank Hospital, Atlanta, Georgia

Boston Children's Hospital, Boston, Massachusetts

Atlantic Children's Health-Pediatric Gastroenterology & Nutrition, Morristown, New Jersey

Goryeb Children's Hospital (Endoscopy only), Morristown, New Jersey

Atlantic Health System- Morristown Medical Center (Pharmacy), Morristown, New Jersey

Northwell Health - Cohen Children's Medical Center, Lake Success, New York

Northwell Health - Cohen Children's Medical Center, New Hyde Park, New York

Columbia University Irving Medical Center, New York, New York

CUIMC Research Pharmacy - Milstein Hospital (Pharmacy Only), New York, New York

Morgan Stanley Children's Hospital, CUIMC, New York, New York

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

Buerger Center for Advanced Pediatric Care, Philadelphia, Pennsylvania

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

Roberts Center for Pediatric Research, Philadelphia, Pennsylvania

Texas Children's Hospital - RRO Regulatory (Administrative Offices - Regulatory Location), Houston, Texas

Texas Children's Hospital, Houston, Texas

Seattle Children's Hospital, Seattle, Washington

The Royal Children's Hospital, Parkville, Victoria

Universitaire Ziekenhuizen Leuven, Leuven, Vlaams Brabant

Hôpital Universitaire Des Enfants Reine Fabiola, Brussels, Not set

Cliniques Universitaires Saint-Luc, Brussels, Not set

Universitair Ziekenhuis Brussel, Brussel, Not set

Stollery Children's Hospital University of Alberta, Edmonton, Alberta

British Columbia Children's Hospital, Vancouver, British Columbia

IWK Health Centre, Halifax, Nova Scotia

London Health Sciences Centre - Children's Hospital, London, Ontario

The Hospital for Sick Children - Division of Gastroenterology, Hepatology and Nutrition, Toronto, Ontario

CHU Sainte-Justine, Montreal, Quebec

Tampereen yliopistollinen sairaala, Tampere, Not set

CHU de Lyon - Hôpital Femme Mère Enfant, BRON Cedex, Not set

Hôpital Necker Enfants Malades, Paris, Not set

Dr. von Haunersches Kinderspital, LMU, Munich, Bavaria

Debreceni Egyetem Klinikai Kozpont, Debrecen, Hajdú-bihar

Szegedi Tudomanyegyetem Szent-Gyorgyi Albert Klinikai Kozpont, Szeged, Not set

Shamir Medical Center (Assaf Harofeh), Be'er Ya'akov, Not set

Lady Davis Carmel Medical Center, Haifa, Not set

Shaare Zedek Medical Center, Jerusalem, Not set

Schneider Children's Medical Center of Israel, Petah Tikva, Not set

Tel-Aviv Sourasky Medical Center, Tel Aviv, Not set

ASST Papa Giovanni XXIII Epatologia e Gastroenterologia Pediatrica e dei Trapianti, Bergamo, BG

A.O.U. Federico II, Napoli, Naples

Azienda Ospedaliero - Universitaria Policlinico Umberto I di Roma, Roma, RM

Azienda USL di Bologna - IRCCS ISNB - Programma Gastroenterologia Pediatrica, Bologna, Not set

Aichi Children's Health and Medical Center, Obu-shi, Aichi

Kurume University Hospital, Kurume-shi, Fukuoka

Gunma University Hospital, Maebashi, Gunma

Miyagi Children's Hospital, Sendai-shi, Miyagi

Osaka Women's and Children's Hospital, Izumi, Osaka

Osaka Medical and Pharmaceutical University Hospital, Takatsuki-shi, Osaka

Saitama Prefectural Children's Medical Center, Saitama-shi, Saitama

Jichi Medical University Hospital, Shimotsuke, Tochigi

Juntendo University Hospital, Bunkyo-ku, Tokyo

National Center for Child Health and Development, Setagaya-ku, Tokyo

Amsterdam UMC, location VUmc Boelelaan, Amsterdam, Not set

Erasmus Medical Center - Sophia Children's Hospital, Rotterdam, Not set

Instytut "Centrum Zdrowia Matki Polki", Lodz, Not set

Korczowski Bartosz, Gabinet Lekarski, Rzeszow, Not set

WIP Warsaw IBD Point Profesor Kierkus, Warsaw, Not set

Instytut "Pomnik - Centrum Zdrowia Dziecka", Warszawa, Not set

Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego we Wroclawiu, Wroclaw, Not set

Narodny ustav detskych chorob, Bratislava, Not set

Hospital Infantil Universitario Niño Jesus, Madrid, Not set

Sahlgrenska Universitetssjukhuset, Göteborg, Not set

Sachsska Children's and Youth Hospital/South General Hospital, Stockholm, Not set

Karolinska Universitetssjukhuset Barngastroenterologi, hepatologi och nutrition, Stockholm, Not set

King's College Hospital NHS Foundation Trust, London, Greater London

Birmingham Women's and Children's NHS Foundation Trust, Birmingham, WEST Midlands

NHS Lothian, Edinburgh, Not set

Bart's Health NHS Trust, London, Not set

Conditions: Ulcerative Colitis

Learn More ›

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

NCT06422806

Recruiting

This phase III trial compares the effect of immunotherapy (pembrolizumab) plus chemotherapy (doxorubicin) to chemotherapy (doxorubicin) alone in treating patients with undifferentiated pleomorphic sarcoma (UPS) or a related poorly differentiated sarcoma that has spread from where it first started (primary site) to other places in the body (metastatic) or that cannot be removed by surgery (unresectable). Doxorubicin is in a class of medications called anthracyclines. Doxorubicin damages the cell'... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/12/2025

Locations: Mayo Clinic Hospital in Arizona, Phoenix, Arizona +198 locations

Mayo Clinic Hospital in Arizona, Phoenix, Arizona

Banner University Medical Center - Tucson, Tucson, Arizona

University of Arizona Cancer Center-North Campus, Tucson, Arizona

Kaiser Permanente Dublin, Dublin, California

Kaiser Permanente-Fremont, Fremont, California

Kaiser Permanente-Fresno, Fresno, California

Keck Medicine of USC Koreatown, Los Angeles, California

Los Angeles General Medical Center, Los Angeles, California

USC / Norris Comprehensive Cancer Center, Los Angeles, California

Cedars Sinai Medical Center, Los Angeles, California

Kaiser Permanente-Modesto, Modesto, California

USC Norris Oncology/Hematology-Newport Beach, Newport Beach, California

Kaiser Permanente-Oakland, Oakland, California

Stanford Cancer Institute Palo Alto, Palo Alto, California

Kaiser Permanente-Roseville, Roseville, California

Kaiser Permanente Downtown Commons, Sacramento, California

Kaiser Permanente-South Sacramento, Sacramento, California

Kaiser Permanente-San Francisco, San Francisco, California

UCSF Medical Center-Mission Bay, San Francisco, California

Kaiser Permanente-Santa Teresa-San Jose, San Jose, California

Kaiser Permanente San Leandro, San Leandro, California

Kaiser San Rafael-Gallinas, San Rafael, California

Kaiser Permanente Medical Center - Santa Clara, Santa Clara, California

Kaiser Permanente-Santa Rosa, Santa Rosa, California

Kaiser Permanente-South San Francisco, South San Francisco, California

Kaiser Permanente-Vallejo, Vallejo, California

Kaiser Permanente-Walnut Creek, Walnut Creek, California

UCHealth University of Colorado Hospital, Aurora, Colorado

Poudre Valley Hospital, Fort Collins, Colorado

Cancer Care and Hematology-Fort Collins, Fort Collins, Colorado

UCHealth Greeley Hospital, Greeley, Colorado

Medical Center of the Rockies, Loveland, Colorado

Beebe South Coastal Health Campus, Millville, Delaware

Helen F Graham Cancer Center, Newark, Delaware

Medical Oncology Hematology Consultants PA, Newark, Delaware

Beebe Health Campus, Rehoboth Beach, Delaware

UM Sylvester Comprehensive Cancer Center at Coral Gables, Coral Gables, Florida

UM Sylvester Comprehensive Cancer Center at Coral Springs, Coral Springs, Florida

UM Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach, Florida

University of Florida Health Science Center - Gainesville, Gainesville, Florida

UM Sylvester Comprehensive Cancer Center at Hollywood, Hollywood, Florida

Mayo Clinic in Florida, Jacksonville, Florida

University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida

UM Sylvester Comprehensive Cancer Center at Kendall, Miami, Florida

UM Sylvester Comprehensive Cancer Center at Plantation, Plantation, Florida

Emory University Hospital Midtown, Atlanta, Georgia

Kaiser Permanente Moanalua Medical Center, Honolulu, Hawaii

Saint Alphonsus Cancer Care Center-Boise, Boise, Idaho

Saint Alphonsus Cancer Care Center-Caldwell, Caldwell, Idaho

Kootenai Health - Coeur d'Alene, Coeur d'Alene, Idaho

Saint Alphonsus Cancer Care Center-Nampa, Nampa, Idaho

Kootenai Clinic Cancer Services - Post Falls, Post Falls, Idaho

Kootenai Clinic Cancer Services - Sandpoint, Sandpoint, Idaho

Advocate Outpatient Center - Aurora, Aurora, Illinois

Advocate Good Shepherd Hospital, Barrington, Illinois

Illinois CancerCare-Bloomington, Bloomington, Illinois

Illinois CancerCare-Canton, Canton, Illinois

Illinois CancerCare-Carthage, Carthage, Illinois

Centralia Oncology Clinic, Centralia, Illinois

Northwestern University, Chicago, Illinois

University of Illinois, Chicago, Illinois

University of Chicago Comprehensive Cancer Center, Chicago, Illinois

Advocate Illinois Masonic Medical Center, Chicago, Illinois

AMG Crystal Lake - Oncology, Crystal Lake, Illinois

Carle at The Riverfront, Danville, Illinois

Cancer Care Specialists of Illinois - Decatur, Decatur, Illinois

Decatur Memorial Hospital, Decatur, Illinois

Northwestern Medicine Cancer Center Kishwaukee, DeKalb, Illinois

Illinois CancerCare-Dixon, Dixon, Illinois

Advocate Good Samaritan Hospital, Downers Grove, Illinois

Carle Physician Group-Effingham, Effingham, Illinois

Crossroads Cancer Center, Effingham, Illinois

Advocate Sherman Hospital, Elgin, Illinois

Elmhurst Memorial Hospital, Elmhurst, Illinois

Illinois CancerCare-Eureka, Eureka, Illinois

Illinois CancerCare-Galesburg, Galesburg, Illinois

Northwestern Medicine Cancer Center Delnor, Geneva, Illinois

Northwestern Medicine Glenview Outpatient Center, Glenview, Illinois

Northwestern Medicine Grayslake Outpatient Center, Grayslake, Illinois

Ingalls Memorial Hospital, Harvey, Illinois

Advocate South Suburban Hospital, Hazel Crest, Illinois

Illinois CancerCare-Kewanee Clinic, Kewanee, Illinois

Northwestern Medicine Lake Forest Hospital, Lake Forest, Illinois

AMG Libertyville - Oncology, Libertyville, Illinois

Condell Memorial Hospital, Libertyville, Illinois

Illinois CancerCare-Macomb, Macomb, Illinois

Carle Physician Group-Mattoon/Charleston, Mattoon, Illinois

Edward Hospital/Cancer Center, Naperville, Illinois

UC Comprehensive Cancer Center at Silver Cross, New Lenox, Illinois

Cancer Care Center of O'Fallon, O'Fallon, Illinois

Advocate Christ Medical Center, Oak Lawn, Illinois

Northwestern Medicine Orland Park, Orland Park, Illinois

University of Chicago Medicine-Orland Park, Orland Park, Illinois

Illinois CancerCare-Ottawa Clinic, Ottawa, Illinois

Advocate Lutheran General Hospital, Park Ridge, Illinois

Illinois CancerCare-Pekin, Pekin, Illinois

Illinois CancerCare-Peoria, Peoria, Illinois

Illinois CancerCare-Peru, Peru, Illinois

Edward Hospital/Cancer Center?Plainfield, Plainfield, Illinois

Illinois CancerCare-Princeton, Princeton, Illinois

Southern Illinois University School of Medicine, Springfield, Illinois

Springfield Clinic, Springfield, Illinois

Springfield Memorial Hospital, Springfield, Illinois

Carle Cancer Center, Urbana, Illinois

Northwestern Medicine Cancer Center Warrenville, Warrenville, Illinois

Illinois CancerCare - Washington, Washington, Illinois

UChicago Medicine Northwest Indiana, Crown Point, Indiana

Indiana University/Melvin and Bren Simon Cancer Center, Indianapolis, Indiana

Sidney and Lois Eskenazi Hospital, Indianapolis, Indiana

UI Health Care Mission Cancer and Blood - Ankeny Clinic, Ankeny, Iowa

Saint Anthony Regional Hospital, Carroll, Iowa

UI Health Care Mission Cancer and Blood - Des Moines Clinic, Des Moines, Iowa

Broadlawns Medical Center, Des Moines, Iowa

UI Healthcare Mission Cancer and Blood - Fort Dodge, Fort Dodge, Iowa

University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa

The James Graham Brown Cancer Center at University of Louisville, Louisville, Kentucky

UofL Health Medical Center Northeast, Louisville, Kentucky

Louisiana Hematology Oncology Associates LLC, Baton Rouge, Louisiana

Dana-Farber Cancer Institute, Boston, Massachusetts

University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan

Henry Ford Macomb Hospital-Clinton Township, Clinton Township, Michigan

Henry Ford Hospital, Detroit, Michigan

Henry Ford Medical Center-Columbus, Novi, Michigan

Sanford Joe Lueken Cancer Center, Bemidji, Minnesota

Essentia Health - Deer River Clinic, Deer River, Minnesota

Essentia Health Cancer Center, Duluth, Minnesota

Essentia Health Hibbing Clinic, Hibbing, Minnesota

Mayo Clinic in Rochester, Rochester, Minnesota

Essentia Health Sandstone, Sandstone, Minnesota

Essentia Health Virginia Clinic, Virginia, Minnesota

Washington University School of Medicine, Saint Louis, Missouri

Siteman Cancer Center-South County, Saint Louis, Missouri

Community Hospital of Anaconda, Anaconda, Montana

Billings Clinic Cancer Center, Billings, Montana

Bozeman Health Deaconess Hospital, Bozeman, Montana

Benefis Sletten Cancer Institute, Great Falls, Montana

Logan Health Medical Center, Kalispell, Montana

Community Medical Center, Missoula, Montana

Nebraska Medicine-Bellevue, Bellevue, Nebraska

Nebraska Medicine-Village Pointe, Omaha, Nebraska

University of Nebraska Medical Center, Omaha, Nebraska

Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon, New Hampshire

Roswell Park Cancer Institute, Buffalo, New York

Northwell Health/Center for Advanced Medicine, Lake Success, New York

Duke University Medical Center, Durham, North Carolina

Sanford Bismarck Medical Center, Bismarck, North Dakota

Sanford Broadway Medical Center, Fargo, North Dakota

Sanford Roger Maris Cancer Center, Fargo, North Dakota

UH Seidman Cancer Center at UH Avon Health Center, Avon, Ohio

UHHS-Chagrin Highlands Medical Center, Beachwood, Ohio

Miami Valley Hospital South, Centerville, Ohio

Case Western Reserve University, Cleveland, Ohio

Cleveland Clinic Foundation, Cleveland, Ohio

Ohio State University Comprehensive Cancer Center, Columbus, Ohio

Miami Valley Hospital, Dayton, Ohio

Premier Blood and Cancer Center, Dayton, Ohio

Miami Valley Hospital North, Dayton, Ohio

Atrium Medical Center-Middletown Regional Hospital, Franklin, Ohio

Miami Valley Cancer Care and Infusion, Greenville, Ohio

Upper Valley Medical Center, Troy, Ohio

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Saint Alphonsus Cancer Care Center-Ontario, Ontario, Oregon

Oregon Health and Science University, Portland, Oregon

Pennsylvania Hospital, Philadelphia, Pennsylvania

Thomas Jefferson University Hospital, Philadelphia, Pennsylvania

Fox Chase Cancer Center, Philadelphia, Pennsylvania

Allegheny General Hospital, Pittsburgh, Pennsylvania

University of Pittsburgh Cancer Institute (UPCI), Pittsburgh, Pennsylvania

Medical University of South Carolina, Charleston, South Carolina

Sanford Cancer Center Oncology Clinic, Sioux Falls, South Dakota

Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota

Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee

University of Virginia Cancer Center, Charlottesville, Virginia

VCU Massey Comprehensive Cancer Center, Richmond, Virginia

Duluth Clinic Ashland, Ashland, Wisconsin

Aurora Cancer Care-Southern Lakes VLCC, Burlington, Wisconsin

Aurora Saint Luke's South Shore, Cudahy, Wisconsin

Aurora Health Care Germantown Health Center, Germantown, Wisconsin

Aurora Cancer Care-Grafton, Grafton, Wisconsin

Aurora BayCare Medical Center, Green Bay, Wisconsin

Aurora Cancer Care-Kenosha South, Kenosha, Wisconsin

Aurora Bay Area Medical Group-Marinette, Marinette, Wisconsin

Aurora Cancer Care-Milwaukee, Milwaukee, Wisconsin

Aurora Saint Luke's Medical Center, Milwaukee, Wisconsin

Medical College of Wisconsin, Milwaukee, Wisconsin

Aurora Sinai Medical Center, Milwaukee, Wisconsin

ProHealth D N Greenwald Center, Mukwonago, Wisconsin

ProHealth Oconomowoc Memorial Hospital, Oconomowoc, Wisconsin

Vince Lombardi Cancer Clinic - Oshkosh, Oshkosh, Wisconsin

Aurora Cancer Care-Racine, Racine, Wisconsin

Vince Lombardi Cancer Clinic-Sheboygan, Sheboygan, Wisconsin

Aurora Medical Center in Summit, Summit, Wisconsin

Vince Lombardi Cancer Clinic-Two Rivers, Two Rivers, Wisconsin

ProHealth Waukesha Memorial Hospital, Waukesha, Wisconsin

UW Cancer Center at ProHealth Care, Waukesha, Wisconsin

Aurora Cancer Care-Milwaukee West, Wauwatosa, Wisconsin

Aurora West Allis Medical Center, West Allis, Wisconsin

CancerCare Manitoba, Winnipeg, Manitoba

University Health Network-Princess Margaret Hospital, Toronto, Ontario

Conditions: Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8, Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8, Metastatic Undifferentiated Pleomorphic Sarcoma, Unresectable Undifferentiated Pleomorphic Sarcoma

Learn More ›

A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

NCT06819878

Recruiting

This Phase III, multicenter, double-blind, placebo-controlled treat-through study will evaluate the efficacy and safety of induction and maintenance therapy with Afimkibart (also known as RO7790121) in participants with moderately to severely active Crohn's disease (CD).

Gender:

ALL

Ages:

Between 16 years and 80 years

Trial Updated:

08/12/2025

Locations: Digestive Health Specialists of the Southeast (Gastroenterology Associates of Dothan) - Dothan, Dothan, Alabama +180 locations

Digestive Health Specialists of the Southeast (Gastroenterology Associates of Dothan) - Dothan, Dothan, Alabama

Arizona Digestive Health, P.C (ADH), Sun City, Arizona

Valley View Internal Medicine, Garden Grove, California

310 Clinical Research, Inglewood, California

Gastro Care Associates, Lancaster, California

Om Research LLC, Lancaster, California

United Gastroenterologists, Los Alamitos, California

Acclaim Clinical Research, Inc., San Diego, California

UCSF/Medical Center at Mount Zion, San Francisco, California

Rocky Mountain Gastroenterology, Littleton, Colorado

Peak Gastroenterology Surgery Center, Lone Tree, Colorado

Access Research Institute, Brooksville, Florida

Gastro Florida, Clearwater, Florida

HealthMed Clinical Center Inc., Coral Gables, Florida

Hi Tech and Global Research, LLC, Coral Gables, Florida

The Sister Life Research, Hialeah, Florida

NeoClinical Research, Hialeah, Florida

Clinical Research of Osceola, LLC, Kissimmee, Florida

Florida Research Institute - Lakewood, Lakewood Ranch, Florida

LCC Medical Research Institute, LLC, Miami, Florida

Ambert Medical Research, Miami, Florida

Orlando Regional Healthcare, Orlando, Florida

Nodal Medical Center Research - NMC, Tampa, Florida

University of South Florida School of Medicine Morsani Center for Advanced Health Care, Tampa, Florida

Guardian Angel Research Center, LLC, Tampa, Florida

Theia Clinical Research Centers, LLC, Temple Terrace, Florida

Digestive Healthcare of Georgia, Atlanta, Georgia

Atlanta Gastroenterology Associates, Atlanta, Georgia

Gastroenterology Associates of Central Georgia, Macon, Georgia

Grand Teton Research Group, PLLC, Idaho Falls, Idaho

Illinois Gastroenterology Group-Glenview powered by GI Alliance, Glenview, Illinois

GI Alliance - Gurnee, Gurnee, Illinois

Gastroenterology Health Partners, PLLC, New Albany, Indiana

Kansas Gastroenterology, LLC under Clinical Trials Network, Wichita, Kansas

Tri-State Gastroenterology Associates, Crestview Hills, Kentucky

Gastroenterology Health Partners, PLLC, Louisville, Kentucky

Brigham and Women's Hospital, Boston, Massachusetts

Michigan Center of Medical Research, Farmington Hills, Michigan

Gastroenterology Associates and Endoscopy Center of North Mississippi, Oxford, Mississippi

Delta Gastroenterology & Endoscopy Center, Southaven, Mississippi

Las Vegas Clinical Trials, LLC, North Las Vegas, Nevada

Lenox Hill Hospital, New York, New York

DiGiovanna Inst for Med Ed&Res, North Massapequa, New York

Queens Village Medical Care, Queens Village, New York

Gastroenterology Group of Rochester under CTNx, Rochester, New York

Omega Research North Carolina, LLC, Fuquay-Varina, North Carolina

Monroe Biomedical Research, Monroe, North Carolina

Dayton Gastroenterology, Inc., Beavercreek, Ohio

Ohio Gastroenterology Group, Columbus, Ohio

The Ohio State University Wexner Medical Center, Columbus, Ohio

Gastro Intestinal Research Institute of Northern Ohio, Westlake, Ohio

Central Sooner Research, Norman, Oklahoma

Frontier Clinical Re search, LLC, Uniontown, Pennsylvania

University Gastroenterology, Providence, Rhode Island

Gastroenterology Associates, PA PA of Greenville, Greenville, South Carolina

Gastro One, Germantown, Tennessee

Quality Medical Research, Nashville, Tennessee

Texas Clinical Research Institute, LLC, Arlington, Texas

Proactive El Paso,LLC, El Paso, Texas

Amel Med LLC, Georgetown, Texas

Cano Medical Center, Harlingen, Texas

TDDC dba GI Alliance Research, Mansfield, Texas

SMS Clinical Research, LLC, Mesquite, Texas

Gastroenterology Research of America, LLC, San Antonio, Texas

GI Alliance - Southlake, Southlake, Texas

Tyler Research Institute, LLC, Tyler, Texas

Tidewater Gastroenterology Pllc T/A Gastro. Assoc. of Tidewater, Chesapeake, Virginia

Emeritas Research Group, Lansdowne Town Center, Virginia

Gastroenterology Consultants and Endoscopy Center of Southwest Virginia, Roanoke, Virginia

Tidewater Physicians Multispecialty Group (TPMG) - Clinical Research Division - Williamsburg, Williamsburg, Virginia

The Vancouver Clinic, Vancouver, Washington

Hospital Britanico, Ciudad Autonoma Bs As, Not set

Royal Prince Alfred Hospital, Sydney, New South Wales

Mater Misericordiae Limited, South Brisbane, Queensland

Barmherzige Brüder Wien, Wien, Not set

Medizinische Universität Wien, Wien, Not set

AZORG Campus Aalst-Moorselbaan, Aalst, Not set

Cliniques Universitaires St-Luc, Bruxelles, Not set

UZ Antwerpen, Edegem, Not set

AZ Maria Middelares, Gent, Not set

AZ Sint Lucas (Sint Lucas), Gent, Not set

Jessa Zkh (Campus Virga Jesse), Hasselt, Not set

CHC MontLégia, Liege, Not set

CHU de Liège (Sart Tilman), Liège, Not set

CHU HELORA - Hôpital de Mons - Site Kennedy, Mons, Not set

Vitaz, Sint Niklaas, Not set

Hospital de Clinicas de Porto Alegre X, Porto Alegre, Rio Grande Do Sul

CPQuali Pesquisa Clinica Ltda, Sao Paulo, São Paulo

South Edmonton Gastroenterology, Edmonton, Alberta

C.I.C. Mauricie, Trois-rivieres, Quebec

Hospital Guillermo Grant Benavente, Concepcion, Not set

Medwal, Santiago, Not set

Clinica Universidad de Los Andes, Santiago, Not set

Peking University Third Hospital, Beijing, Not set

the First Hospital of Jilin University, Changchun, Not set

Third Xiangya Hospital Centrel South University, Changsha, Not set

West China Hospital of Sichuan University, Chengdu City, Not set

Chongqing General Hospital, Chongqing City, Not set

The First Affiliated Hospital Of Fujian Medical University, Fuzhou City, Not set

The second Affiliated Hospital of Guangzhou Medical University, Guangzhou City, Not set

The sixth affiliated hospital of Sun Yat-Sen University, Guangzhou City, Not set

Zhejiang Province Traditional Chinese Medical Hospital, Hangzhou City, Not set

Sir Run Run Shaw Hospital Zhejiang University, Hangzhou City, Not set

Anhui Provincial Hospital, Hefei, Not set

The First Affiliated Hospital of Anhui Medical University, Hefei, Not set

Huizhou Central People's Hospital, Huizhou, Not set

The 1st Affiliated Hospital of Nanchang Unversity, Nanchang City, Not set

The First Affiliate Hospital of Guangxi Medical University, Nanning, Not set

The First Affiliated Hospital of Ningbo University, Ningbo City, Not set

Shanghai East Hospital, Shanghai City, Not set

Peking University Shenzhen Hospital, Shenzhen, Not set

Taizhou Hospital Of Zhejiang Province, Taizhou City, Not set

The Central Hospital of Wuhan, Wuhan City, Not set

Ren Min Hospital Affiliated Wu Han University, Wuhan, Not set

Wuxi People's Hospital, Wuxi, Not set

Zhongshan Hospital Xiamen University, Xiamen, Not set

The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Not set

Zhuzhou Central Hospital, Zhuzhou, Not set

SurGal Clinic s.r.o., Brno, Not set

Gastroenterologie s.r.o., Hradec Kralove, Not set

Fakultni nemocnice Hradec Kralove, Hradec Kralove, Not set

Herlev Hospital, Herlev, Not set

CEMDOE (Centro Médico de Diabetes, Obesidad y Especialidades), Santo Domingo, Not set

CHU Amiens - Hopital Sud, Amiens, Not set

Hopital Nord, Marseille, Not set

CHU Nice - Hopital de l'Archet 2, Nice, Not set

CHU Bordeaux - Hôpital Haut-Lévêque, Pessac, Not set

Hopital Robert Debre, Reims, Not set

CHU de Rennes - Hopital de Pontchaillo, Rennes, Not set

CHU Saint Etienne - Hôpital Nord, Saint Etienne, Not set

Charite - Campus Benjamin Franklin, Berlin, Not set

AGAPLESION Markus-Krankenhaus, Frankfurt, Not set

Klinik Johann Wolfgang von Goethe Uni, Frankfurt, Not set

Universitaetsklinikum Halle (Saale), Halle, Not set

Universitaetsklinikum Jena, Jena, Not set

Klinikum Mannheim GmbH Universitätsklinikum, Mannheim, Not set

Universitätsklinikum Ulm, Ulm, Not set

Obudai Egeszsegugyi Centrum Kft., Budapest, Not set

Semmelweis Egyetem, Budapest, Not set

Pannonia Maganorvosi Centrum, Budapest, Not set

Clinexpert Gyongyos Kft, Gyongyos, Not set

Clinfan Szolgaltato Kft., Szekszard, Not set

Fejer Varmegyei Szent György Egyetemi Oktatokorhaz, Székesfehérvár, Not set

Chaim Sheba Medical Center, Ramat Gan, Not set

Ospedale Isola Tiberina Gemelli, Roma, Lazio

ASST Rhodense - Ospedale di Rho, Rho, Lombardia

Ospedale Mauriziano Umberto I, Torino, Piemonte

Gamagori City Hospital, Aichi, Not set

Tsujinaka Hospital Kashiwanoha, Chiba, Not set

Kinshukai Infusion Clinic, Osaka, Not set

Matsuda Hospital, Shizuoka, Not set

Boca Clinical Trials Mexico S.C. (Guadalajara), Guadalajara, Jalisco

Medical Care & Research SA de CV, Mérida, Yucatan

Universitair Medisch Centrum Utrecht, Utrecht, Not set

Centrum Medyczne "Medis", Bydgoszcz, Not set

Centrum Medyczne Lukamed Joanna Luka-Wendrowska, Chojnice, Not set

Endo-Med Sp. z o.o., Karczew, Not set

Allmedica Badania Kliniczne Sp z o.o. Sp K., Nowy Targ, Not set

SOLUMED Centrum Medyczne, Pozna?, Not set

Gastromed Sp. z o.o., Toru?, Not set

WIP Warsaw IBD Point Profesor Kierkus, Warszawa, Not set

Centralny Szpital Kliniczny MSW w Warszawie, Warszawa, Not set

Przychodnia EuroMediCare, Wroc?aw, Not set

Melita Medical, Wroc?aw, Not set

Vistamed & Vertigo Spó?Ka Z Ograniczon? Odpowiedzialno?Ci?, Wroc?aw, Not set

ETG Zamosc, Zamosc, Not set

Hospital de Braga, Braga, Not set

Hospital de Santa Maria, Lisboa, Not set

Hospital de Sao Joao, Porto, Not set

Klinical Investigations Group LLC, San Juan, Not set

Hospital Universitario Marques de Valdecilla, Santander, Cantabria

Hospital Universitario La Paz, Madrid, Not set

Hospital Universitario Reina Sofía, Murcia, Not set

China Medical University Hospital, Taichung City, Not set

Division of Gastroenterology, Depart of Medicine, Fac of Med., Chulalongkorn University, Bangkok, Not set

Division of Gastroenterology, Depart of Internal Med, Siriraj H, Mahidol Uni, Bangkok, Not set

Khon Kaen Uni, Khon Kaen, Not set

Division of Gastroenterology, Depart of Medicine, Fac. of Med, Songklanagarind University, Songkhla, Not set

Royal Liverpool University Hospital, Liverpool, Not set

King College Hospital NHS Foundation Trust, London, Not set

Queen Anne Street Medical Centre, London, Not set

Conditions: Moderately to Severely Active Crohns Disease

Learn More ›

Tranexamic Acid Use on Pain, Mobility and Bleeding Following Total Hip and Total Knee Arthroplasty

NCT06208267

Recruiting

Tranexamic acid (TXA) is an anti-fibrinolytic agent developed in the 1960s that has been safely used to reduce blood loss, transfusion rates and bleeding-associated mortality in trauma, obstetrics and orthopedic surgery, including hip fracture care and arthroplasty. The efficacy and safety profile of TXA has been extensively studied in numerous clinical trials and observational studies. Its wide range of applications, combined with its favourable risk-benefit ratio, has led to the incorporation... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/12/2025

Locations: St. Mary's Hospital Center, Montreal, Quebec

Conditions: Postoperative Bleeding

Learn More ›

Frequency of Selected Single Nucleotide Polymorphisms in Huntington Disease Gene Expansion Carriers

NCT06667414

Recruiting

For participation in this epidemiological study, a single-day visit at the study site is required. Participants will be recruited from Huntington Disease clinics, and they will be asked to answer questions regarding their demographics, including sex, age, race and ethnicity, and their medical and medication history. At the end of the visit, a blood sample will be drawn to allow testing with a sequencing assay that is specifically designed for phasing single nucleotide polymorphisms (SNPs) on the... Read More

Gender:

ALL

Ages:

Between 25 years and 60 years

Trial Updated:

08/12/2025

Locations: Uab Medicine, Birmingham, Alabama +40 locations

Uab Medicine, Birmingham, Alabama

Barrow Neurological Institute, Phoenix, Arizona

University of California San Diego, La Jolla, California

University of California Davis Medical System, Sacramento, California

CenExel Rocky Mountain Clinical Research, LLC, Englewood, Colorado

University of South Florida, Tampa, Florida

Northwestern University, Chicago, Illinois

University of Iowa Hospitals and Clinics, Iowa City, Iowa

John Hopkins University School of Medicine, Baltimore, Maryland

Beth Israel Deaconess Medical Center, Boston, Massachusetts

University of Pittsburgh, Pittsburgh, Pennsylvania

EvergreenHealth Investigational Drug Services, Kirkland, Washington

Hospital Britanico de Buenos Aires, Ciudad Autonoma Buenos Aires, Not set

Calvary Health Care Bethlehem, Caulfield South, New South Wales

Westmead Hospital, Westmead, New South Wales

Royal Melbourne Hospital, Parkville, Victoria

University of Alberta, Edmonton, Alberta

University of British Columbia Hospital, Vancouver, British Columbia

Centricity Research, Halifax, Nova Scotia

North York General Hospital, Toronto, Ontario

McGill University, Montreal, Quebec

Charité - Universitätsmed. Berlin, Klinik für Psychiatrie und Psychotherapie, Berlin, Not set

St. Josef-Hospital, Neurologische Klinik der Ruhr-Uni, Bochum, Not set

Universitätsklinikum Erlangen, Abteilung Molekulare Neurologie, Erlangen, Not set

Universitätsklinikum Ulm, Ulm, Not set

Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Lombardia

Auckland DHB - Neurlogy Department, Auckland, Not set

New Zealand Brain Research Institute, Christchurch, Not set

Wellington Hospital, Wellington, Not set

Szpital Sw. Wojciecha, Gda?sk, Not set

Wojskowy Instytut Medycyny Lotniczej, Warszawa, Not set

Unidade Local de Saude de Santa Maria, E.P.E. - Hospital de Santa Maria, Lisboa, Not set

CNS - Campus Neurológico, Torres Vedras, Not set

Hospital Universitario de Badajoz, Badajoz, Not set

Hospital de la Santa Creu i Sant Pau, Barcelona, Not set

Hospital Universitario de Burgos. Servicio de Neurología, Burgos, Not set

Hospital Ramon y Cajal, Madrid, Not set

Birmingham and Solihull Mental Health Foundation NHS Trust, Birmingham, Not set

Addenbrookes Hospital, Cambridge, Not set

National Hospital For Neurology and Neurosurgery, London, Not set

John Radcliffe Hospital, Oxford, Not set

Conditions: Huntington Disease

Learn More ›