All Clinical Trials in Canada

A listing of 3905 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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A Clinical Trial of Study Medicine (Marstacimab) in Pediatric Patients With Hemophilia A or Hemophilia B

NCT05611801

Recruiting

The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called marstacimab) for the potential treatment of hemophilia in pediatric patients. This study will enroll pediatric participants from ages 1 to 17 years in a sequential manner. The study will open enrollment to adolescent participants aged 12 to 17 years first. Then children aged 6 to 11 years will be permitted to enroll. Lastly, children aged 1 to 5 years will be permitted to enroll. This study will enroll participants who: * have severe Hemophilia A or moderately severe to severe Hemophilia B (with or without inhibitors) * have accurate historical records documenting all factor VIII, factor IX, or bypass agent infusions and hemophilia bleed events for at least 1 year prior to entering the study * if a non-inhibitor patient, must be on a stable routine prophylaxis regimen with factor VIII or factor IX replacement products for at least 12 months prior to study entry * if an inhibitor patient, must be on an on-demand bypass treatment regimen during the 12 months prior to study entry All participants in this study will receive marstacimab to use prophylactically. Marstacimab will be given once a week as a subcutaneous (under the skin) shot. The first dose of marstacimab will be given at the study site by the study site staff. During the 12-month treatment period, weekly doses of marstacimab can be given at home, or if preferred, the doses may be given by the study site staff. To help us determine if the study medicine is safe and effective, we will compare participant experiences when they are taking the study medicine to a historical period when they were not. Researchers want to see if the study medicine works to prevent the bleeding episodes commonly experienced by patients with Hemophilia. Participants will be in this study for about 14 months (approximately 1 month in a Screening period, 12 months receiving treatment, and 1 month in a follow-up period) during which they will visit the study site at least 10 times. If preferred, and if local regulations allow it, 2 of the study visits can be completed at the participant's home instead of at the study site. There will also be 6 scheduled telephone calls approximately every 2 months. Read Less

Gender:

MALE

Ages:

Between 1 year and 17 years

Trial Updated:

08/11/2025

Locations: Intermountain - Primary Children's Hospital, Salt Lake City, Utah +59 locations

Intermountain - Primary Children's Hospital, Salt Lake City, Utah

Arbesu Hematología, Mendoza, Not set

Sydney Children's Hospital, Randwick, New South Wales

Royal Children's Hospital, Melbourne, Victoria

Medizinische Universität Wien, Vienna, Wien

HEMOES, Vitoria, Espírito Santo

Stollery Children's Hospital, Edmonton, Alberta

Hamilton Health Sciences - McMaster University Medical Centre, Hamilton, Ontario/canada

Beijing Children's hospital, Capital Medical University, Beijing, Beijing

Southern Medical University Nanfang Hospital, Guangzhou, Guangdong

The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou

Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei

Tongji Hospital of Tongji Medical College of HUST/Pediatric Hematology Department Pharmacy, Wuhan, Hubei

Jiangxi Provincial People's Hospital, Nanchang, Jiangxi

Institute of hematology&blood disease hospital, Tianjin, Tianjin

Detska nemocnice FN Brno, Brno, Brno-město

Rigshospitalet, Copenhagen, Hovedstaden

Aarhus Universitetshospital, Skejby, Aarhus, Midtjylland

Hôpital Universitaire Necker Enfants Malades, Paris, Not set

Charité Campus Virchow-Klinikum, Berlin, Not set

Nirmal Hospital Pvt Ltd., Surat, Gujarat

K.J. Somaiya Hospital, Mumbai, Maharashtra

Nil Ratan Sircar Medical College and Hospital, Kolkata, WEST Bengal

Sheba Medical Center, Ramat Gan, Hamerkaz

IRCCS Istituto Giannina Gaslini, Genova, Liguria

Istituto Clinico Humanitas, Rozzano, Milano

Ospedale Pediatrico Bambino Gesù IRCCS, Rome, Roma

Azienda Ospedaliero Universitaria di Parma, Parma, Not set

Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino, Torino, Not set

Hyogo prefectural Kobe Children's Hospital, Kobe, Hyogo

Nagano Children's Hospital, Azumino, Nagano

Nara Medical University Hospital, Kashihara, Nara

Saitama Prefectural Children's Medical Center, Saitama-shi, Saitama

Saga University Hospital, Saga, Not set

Severance Hospital, Yonsei University Health System, Seoul, Seoul-teukbyeolsi [seoul]

Kyung Hee University Hospital at Gangdong, Seoul, Seoul-teukbyeolsi [seoul]

Kyungpook National University Hospital, Daegu, Taegu-kwangyǒkshi

Arké SMO S.A de C.V, Veracruz, Not set

King Fahad Specialist Hospital - Dammam, Dammam, ASH Sharqīyah

King Faisal Specialist Hospital & Research Center, An Narjis, Not set

Detska fakultna nemocnica Kosice, Kosice, Not set

Univerzitna nemocnica Martin, Martin, Not set

Worthwhile Clinical Trials, Benoni, Gauteng

Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, Gauteng

Hospital Universitario La Paz, Madrid, Not set

Hospital Universitario Miguel Servet, Zaragoza, Not set

Changhua Christian Hospital, Changhua County, Changhua

Taichung Veterans General Hospital, Taichung, Not set

National Taiwan University Hospital, Taipei, Not set

Istanbul Universitesi Istanbul Tıp Fakultesi Hastanesi, İstanbul, İ̇stanbul

Ege Universitesi Hastanesi, Izmir, İ̇zmir

Erciyes University, Talas, Kayseri

Acibadem Adana Hospital, Adana, Not set

Gazi University Health Research and Application Center Gazi Hospital, Ankara, Not set

Erciyes Universitesi Tıp Fakultesi Hastaneleri, Kayseri, Not set

Ondokuz Mayıs Universitesi, Samsun, Not set

Royal Victoria Infirmary, Newcastle upon Tyne, England

Birmingham Children's Hospital, Birmingham, Not set

Evelina London Children's Hospital, London, Not set

Royal Manchester Children's Hospital, Manchester, Not set

Conditions: Hemophilia A, Hemophilia B

Learn More ›

A Clinical Trial Investigating the Safety, Tolerability, and Therapeutic Effects of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Alone for Patients With a Form of Head and Neck Cancer Positive for Human Papilloma Virus 16 and Expressing the Protein PD-L1

NCT04534205

Recruiting

An open-label, controlled, multi-site, interventional, 2-arm, Phase II/III trial of BNT113 in combination with pembrolizumab vs pembrolizumab monotherapy as first line treatment in patients with unresectable recurrent or metastatic HPV16+ HNSCC expressing programmed cell death ligand-1 (PD-L1) with combined positive score (CPS) ≥1. This trial has two parts. Part A, is an initial non-randomized Safety Run-In Phase to confirm the safety and tolerability at the selected dose range level of BNT113... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/11/2025

Locations: California Research Institute, Los Angeles, California +186 locations

California Research Institute, Los Angeles, California

UCLA Cancer Care, Los Angeles, California

Stanford Cancer Institute, Palo Alto, California

Yale University, New Haven, Connecticut

The George Washington Cancer Center, Washington, District of Columbia

University of Miami Miller School of Medicine, Miami, Florida

University Cancer and Blood Center, Athens, Georgia

Winship Cancer Institute, Atlanta, Georgia

Norton Cancer Institute, Louisville, Kentucky

Tufts Medical Center, Boston, Massachusetts

The University of New Mexico Comprehensive Cancer Center, Albuquerque, New Mexico

Montefiore Medical Center, Bronx, New York

Icahn School of Medicine at Mount Sinai, New York, New York

University of Cincinnati Cancer Center, Cincinnati, Ohio

Providence Cancer Institute, Portland, Oregon

MD Anderson Cancer Center, Houston, Texas

MultiCare Regional Cancer Center, Tacoma, Washington

Centro de Oncología e Investigación Buenos Aires COIBA, Berazategui, Not set

Hospital Britanico de Buenos Aires, Ciudad de Buenos Aires, Not set

Instituto de Oncologia de Cordoba, Córdoba, Not set

Centro Oncologico Riojano Integral, La Rioja, Not set

Centro de Investigacion Pergamino SA - Clinica Pergamino, Pergamino, Not set

Instituto de Oncologia de Rosario, Rosario, Not set

Sanatorio Britanico, Rosario, Not set

CAIPO Centro para la Atencion Integral del Paciente Oncologico, San Miguel De Tucumán, Not set

Clinica Viedma, Viedma, Not set

Cancer Research SA, Adelaide, Not set

Bankstown-Lidcombe Hospital, Bankstown, Not set

Flinders Medical Centre, Bedford Park, Not set

Coffs Harbour Hospital, Coffs Harbour, Not set

St Vincent's Hospital, Fitzroy, Not set

Royal North Shore Hospital, Saint Leonards, Not set

John Flynn Private Hospital, Tugun, Not set

Southern Medical Day Care Centre, Wollongong, Not set

LKH - Univ. Klinikum Graz, Graz, Not set

Landeskrankenhaus/ Univ.-Kliniken Innsbruck, Innsbruck, Not set

HNO, Kopf-und Halschirurgie Ordensklinikum Linz Barmherzigen Schwestern, Linz, Not set

Uniklinikum Salzburg, Univ. Klinik fur Innere Medizin III, Salzburg, Not set

Universitair Ziekenhuis Brussel, Bruxelles, Not set

Universitair Ziekenhuis Gent UZ Gent, Gent, Not set

CHR de la Citadelle, Liège, Not set

Fundação PIO XII - Hospital de Amor Barretos, Barretos, Not set

Fundacao Universidade de Caxias do Sul - Instituto de Pesquisas em Saude IPS-UCS, Caxias Do Sul, Not set

Hospital Erasto Gaertner, Curitiba, Not set

Oncosite - Centro de Pesquisa Clinica em Oncologia, Ijuí, Not set

Hospital Marcio Cunha, Ipatinga, Not set

Irmandade Santa Casa de Misericordia de Porto Alegre Hospital Santa Rita, Porto Alegre, Not set

Hospital Mae de Deus, Porto Alegre, Not set

Hospital Sao Lucas da PUCRS, Porto Alegre, Not set

Instituto Nacional de Cancer Jose de Alencar Gomes da Silva - INCA, Rio De Janeiro, Not set

Hospital Sao Rafael, Salvador, Not set

Hospital de Base de Sao Jose do Rio Preto, São José Do Rio Preto, Not set

Instituto do Cancer do Estado de São Paulo, São Paulo, Not set

IBCC - Instituto Brasileiro de Controle do Cancer, Vila Mariana, Not set

Cross Cancer Institute, Edmonton, Not set

British Columbia Cancer Agency, Kelowna, Not set

Jewish General Hospital, Montreal, Not set

McGill University Health Centre, Montréal, Not set

Princess Margaret Cancer Centre, Toronto, Not set

Centro de Estudios Clinicos SAGA, Santiago, Not set

Fundación Arturo López Pérez, Santiago, Not set

James Lind Centro de Investigación del Cáncer, Temuco, Not set

Fakultni Nemocnice Olomouc, Olomouc, Not set

Hospital Na Bulovce (Nemocnice na Bulovce), Prague 8 - Liben, Not set

CHU de BORDEAUX, Hopital Saint Andre, Bordeaux, Not set

CHU de Caen Normandie, Caen, Not set

Centre Georges Francois Leclerc, Dijon Cedex, Not set

Clinique Victor Hugo, Le Mans, Not set

Institut de Radiothérapie Hartmann, GCS CCConcorde, Levallois-Perret, Not set

Hopital de la Timone, Marseille, Not set

Hopital Prive du Confluent, Nantes, Not set

Institut Curie, Paris, Not set

Institut Curie, Groupe Hospitalier Paris Saint-Joseph (GHPSJ), Paris, Not set

CHU de Tours Hopital Bretonneau, Tours, Not set

Hospital Gustave Roussy, Villejuif, Not set

Charite Universitätsklinikum Berlin - Campus Benjamin Franklin, Berlin, Not set

Krankenhaus Nordwest GmbH, Frankfurt am Main, Not set

SRH Wald-Klinikum Gera GmbH, Hamburg, Not set

Kath. Marien Krankenhaus gGmbH, Hamburg, Not set

Medizinische Hochschule Hannover (MHH), Hannover, Not set

Universitaetsklinik Heidelberg, Heidelberg, Not set

Klinik für HNO-Heilkunde, Kopf- und Hals-Chirurgie, Köln, Not set

Universitätsklinikum Leipzig, Leipzig, Not set

UNIVERSITAETSMEDIZIN der Johannes Gutenberg-Universitaet Mainz, Mainz, Not set

Klinikum rechts der Isar der TUM, München, Not set

Univeritätsklinikum Münster, Münster, Not set

Universitaetsmedizin Rostock - Medizinische Klink III (Hamatologie, Onkologie, Palliativmedizin), Rostock, Not set

Caritas Klinikum Saarbrucken St. Theresia, Saarbruecken, Not set

Medizinische Universitaetsklinik Tuebingen, Tübingen, Not set

Universitaetsklinikum Wuerzburg, Würzburg, Not set

Central Hospital of Northern Pest - Military Hospital, Budapest, Not set

Uzsoki Utcai Korhaz Onkologiai Osztaly, Budapest, Not set

DEKK Onkologiai Klinika, Debrecen, Not set

Zala Megyei S. Rafael Korhaz, Zalaegerszeg, Not set

Rambam Health Clinical, Haifa, Not set

Hadassah Medical Center - Sharett Institute of Oncology, Jerusalem, Not set

Rabin Medical Center, Petah tikva, Not set

Tel Aviv Sourasky Medical Center, Tel Aviv, Not set

ASST Spedali Civili Brescia, Brescia, Not set

Mater Salutis Hospital AULSS 9 della Regione Veneto, Legnago, Not set

IRCCS Ospedale San Raffaele, Milano, Not set

IRCCS Istituto Europeo di Oncologia, Milano, Not set

Ospedale del Mare, Napoli, Not set

A.O.U. Maggiore della Carita, Novara, Not set

Azienda Ospedaliera Universitaria Senese Policlinico Le Scotte, Siena, Not set

Azienda Sanitaria Universitaria Integrata Friuli Centrale - Presidio ospedaliero di Udine, Udine, Not set

Chungnam National University Hospital, Daejeon, Not set

Konyang University Hospital, Daejeon, Not set

Chonnam National University Hwasun Hospital, Hwasun, Not set

Korea University Anam Hospital, Seoul, Not set

Severance Hospital, Yonsei University Health System, Seoul, Not set

The Catholic University of Korea, Seoul ST. Mary's Hospital, Seoul, Not set

The Catholic University of Korea St. Vincent's Hospital, Suwon-si, Not set

Ajou University Hospital, Suwon-si, Not set

Centro de Estudios y Prevención del Cáncer (CEPREC), Tuxtla Gutiérrez, Region Chiapas

Centro Estatal de Cancerologia de Chihuahua, Chihuahua, Not set

Cryptex Investigacion SA de CV, Ciudad De México, Not set

Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Not set

Consultorio del Dr. Joaquín Gabriel Reinoso Toledo, Monterrey, Not set

Hospital Universitario "Dr Jose Eleuterio Gonzalez" Centro Universitario contra el Cáncer, Monterrey, Not set

Oaxaca Site Management Organization S. C., Oaxaca de Juarez, Not set

Sociedad de Metabolismo y Corazón S.C., Veracruz, Not set

Centro de Atencion e Investigacion Clinica en Oncologia (CAICO), Yucatán, Not set

Uniwersyteckie Centrum Kliniczne, Gdańsk, Not set

Szpitale Pomorskie Sp.zo.o, Gdynia, Not set

Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie, Gliwice, Not set

Przychodnia Lekarska KOMED Roman Karaszewski, Konin, Not set

MCM Pratia Krakow, Kraków, Not set

Centrum Medyczne Pratia Poznań, Poznań, Not set

Wojskowy Szpital Kliniczny z Poliklinika SP ZOZ, Wrocław, Not set

Centro Clinico Academico, Braga, Not set

Instituto Português de Oncologia de Coimbra Francisco Gentil, E.P.E., Coimbra, Not set

Centro Hospitalar de Vila Nova de Gaia/Espinho, Gaia, Not set

IPO Lisboa Francisco Gentil, Lisboa, Not set

Centro Hospitalar Universitario Lisboa Norte, Lisboa, Not set

Instituto Portugues de Oncologia do Porto Francisco Gentil, E.P.E, Porto, Not set

Hospital Clinic Barcelona, Barcelona, Not set

Hospital Univ. Dr. Josep Trueta, Girona, Not set

Complejo Hospitalario de Jaen, Jaén, Not set

Clinica Universidad de Navarra - Madrid (CUN-M), Madrid, Not set

Hospital Universitario Fundacion Jimenez Diaz, Madrid, Not set

Hospital Universitario La Paz, Madrid, Not set

Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda, Not set

Hospital Regional de Malaga, Malaga, Not set

Hospital Universitario Son Espases, Palma de Mallorca, Not set

Clinica Universidad de Navarra - Pamplona (CUN-P), Pamplona, Not set

Hospital La Fe, Valencia, Not set

Hospital Miguel Servet, Zaragoza, Not set

Sahlgrenska University Hospital, Goteborg, Not set

Skane University Hospital, Lund, Not set

Norrlands University Hospital, Umeå, Not set

Changhua Christian Hospital, Changhua, Not set

Chang Bing Show Chwan Memorial Hospital, Changhua, Not set

Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung City, Not set

Chang Gung Memorial Hospital-Kaohsiung Branch, Kaohsiung, Not set

Taichung Veterans General Hospital, Taichung, Not set

National Taiwan University Hospital, Taipei, Not set

Taipei Veterans General Hospital, Taipei, Not set

Medical Park Seyhan Hospital, Adana, Not set

Ankara Bilkent Sehir Hastanesi, Ankara, Not set

Hacettepe University Cancer Institute, Ankara, Not set

Trakya University, Edirne, Not set

Istanbul Universitesi Onkoloji Enstitusu, Istanbul, Not set

Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Istanbul, Not set

Medipol Mega Universite Hastanesi, Istanbul, Not set

Istanbul Medeniyet University Medical Faculty, Istanbul, Not set

Ege Universitesi Tip Fakultesi Hastanesi - Tulay Aktas Onkoloji Hastanesi, İzmir, Not set

Medical Park - Izmir Hastanesi, İzmir, Not set

Inonu Universitesi - Turgut Ozal Tip Merkezi, Malatya, Not set

Baskent University, Yüreğir, Not set

Aberdeen Royal Infirmary, Aberdeen, Not set

Belfast Health and Social Care Trust, Belfast City Hospital, Belfast, Not set

University Hospitals Birmingham, Queen Elizabeth Hospital, Birmingham, Not set

Addenbrooke's Hospital - Cambridge University Hospitals, Cambridge, Not set

Velindre Cancer Centre, Cardiff, Not set

Beatson West of Scotland Cancer Centre, Glasgow, Not set

Leeds Teaching Hospitals NHS Trust (St James's University Hospital), Leeds, Not set

The Clatterbridge Cancer Centre, Liverpool, Not set

University College London Hospitals, London, Not set

Guy's Cancer Centre, Guy's Hospital, London, Not set

The Royal Marsden Hospital NHS Foundation Trust - Fulham Road, London, Not set

Nottingham University Hospitals NHS Trust, Nottingham, Not set

Oxford Cancer Centre, Oxford, Not set

Royal Preston Hospital Lancashire Teaching Hospitals NHS Foundation Trust, Preston, Not set

University Hospital Southampton NHS Foundation Trust, Southampton, Not set

Mount Vernon Cancer Centre, East and North Hertfordshire NHS Trust, Stevenage, Not set

The Royal Marsden Hospital - Sutton, Sutton, Not set

Conditions: Unresectable Head and Neck Squamous Cell Carcinoma, Metastatic Head and Neck Cancer, Recurrent Head and Neck Cancer

Learn More ›

Longitudinal Study of Xenon-129 MRI Imaging Effects of Cannabis Smoking

NCT03909477

Recruiting

This is a longitudinal study of the long-term health impact of cannabis smoking on the lungs. Participants will be followed over a period of 3 years, and impacts of cannabis smoking on the lungs will be measured with magnetic resonance imaging (MRI) using hyperpolarized xenon-129 gas, pulmonary function tests, exercise capacity, computed tomography images and questionnaires.

Gender:

ALL

Ages:

Between 18 years and 85 years

Trial Updated:

08/11/2025

Locations: Robarts Research Institute; The University of Western Ontario; London Health Sciences Centre, London, Ontario

Conditions: Cannabis Use, Cannabis Smoking, Marijuana Smoking, Marijuana Usage

Learn More ›

A Study to Assess the Effectiveness and Safety of Pacritinib in Patients With VEXAS Syndrome (PAXIS)

NCT06782373

Recruiting

This study is to assess the effectiveness and safety of pacritinib in patients with VEXAS (i.e., Vacuoles in myeloid progenitors, E1 ubiquitin-activating enzyme, X-linked, autoinflammatory manifestations, and somatic) syndrome. 78 patients will be enrolled, randomized to either pacritinib dose A, pacritinib dose B + placebo, or placebo. Randomization will be stratified by prescribed GC dose on the day of randomization.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/11/2025

Locations: Mayo Clinic - Scottsdale, Scottsdale, Arizona +39 locations

Mayo Clinic - Scottsdale, Scottsdale, Arizona

University of Maryland Medical Center Midtown Campus, Baltimore, Maryland

Dana Farber Cancer Institute, Boston, Massachusetts

Mayo Clinic - Rochester, Rochester, Minnesota

NYU Langone Health, New York, New York

Cleveland Clinic - Cleveland, Cleveland, Ohio

The James Cancer Hospital and Solove Research Institute, Columbus, Ohio

UT MD Anderson Cancer Center, Houston, Texas

University of Utah Healthcare, Salt Lake City, Utah

Fred Hutchinson Cancer Center, Seattle, Washington

Vancouver Coastal Health Research Institute, Vancouver, British Columbia

Queen Elizabeth II Health Sciences Center, Halifax, Nova Scotia

Princess Margaret Cancer Centre, Toronto, Ontario

Hospital du Sacre-Coeur in Montreal, Montréal, Quebec

Lille University Hospital Center, Lille, Not set

Saint-Antoine Hospital - APHP, Paris, Not set

Tenon Hospital - APHP, Paris, Not set

Hospices Civils de Lyon - Lyon Sud, Pierre-Bénite, Not set

University Hospital Center of Poitiers, Poitiers, Not set

IUCT-Oncopole, Toulouse, Not set

University Hospital Tuebingen, Medical Clinic II, Hematology, Oncology, Clinical Immunology and Rheumatology, Tuebingen, Baden-Wuerttemberg

Hospital Rechts der Isar of the Technical University of Munich, Clinic and Polyclinic for Internal Medicine III: Hematology and Internal Oncology, Munich, Bavaria

University Hospital Duesseldorf, Duesseldorf, North Rhine-Westphalia

University Hospital Carl Gustav Carus Dresden, Medical Clinic and Polyclinic I, Dresden, Saxony

University Hospital Schleswig-Holstein, Luebeck, Schleswig-Holstein

University Hospital Hamburg-Eppendorf, Hamburg, Not set

Hospital San Raffaele, IRCCS, Unit of Immunology, Rheumatology, Allergy and Rare Diseases, Milan, Not set

University Hospital of Padova, Rheumatology Unit, Department of Medicine - DIMED, Padova, Not set

AUSL of Reggio Emilia - Hospital Arcispedale S. Maria Nuova, Complex Structure of Rheumatology, Reggio Emilia, Not set

Foundation PTV - Polyclinic Tor Vergata Biomedicine and prevention, Roma, Not set

Fukushima Medical University Hospital, Fukushima, Not set

Nagasaki University Hospital, Nagasaki, Not set

Yokohama City University Hospital, Yokohama, Not set

Hospital Clinic of Barcelona, Barcelona, Not set

Catalan Institute of Oncology, Hospital Duran i Reynals, Department of Clinical Hematology, Hospitalet de Llobregat, Not set

University Clinical Hospital of Salamanca, Salamanca, Not set

St James's University Hospital, Leeds, Not set

Royal Free Hospital, London, Not set

King's College Hospital, Department of Hematology, London, Not set

Churchill Hospital, Oxford, Not set

Conditions: VEXAS, VEXAS Syndrome

Learn More ›

A Study Comparing Zasocitinib (TAK-279) With Deucravacitinib in Adults With Plaque Psoriasis

NCT06973291

Recruiting

The main aim of this study is to assess whether zasocitinib works better than deucravacitinib in treating participants with moderate-to-severe plaque psoriasis. Participants will take one tablet daily of either zasocitinib or a matching placebo, along with one capsule daily of either over-encapsulated deucravacitinib or a matching placebo, for a duration of 16 weeks. Participants will be in the study for up to 25 weeks, which includes screening period of up to 35 days, a 16-week treatment peri... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/11/2025

Locations: Johnson Dermatology, Fort Smith, Arkansas +112 locations

Johnson Dermatology, Fort Smith, Arkansas

Burke Pharmaceutical Research, Hot Springs, Arkansas

Zenith Research, Inc., Beverly Hills, California

First OC Dermatology Research Inc., Fountain Valley, California

UNISON Clinical Trials (Shahram Jacobs md inc.), Sherman Oaks, California

Central Connecticut Dermatology, PLLC, Cromwell, Connecticut

Yale University School of Medicine, New Haven, Connecticut

Direct Helpers Research Center, Hialeah, Florida

San Marcus Research Clinic Inc, Miami Lakes, Florida

Advanced Clinical Research Institute, Tampa, Florida

Arlington Dermatology, Rolling Meadows, Illinois

Endeavor Health Clinical Trials, Skokie, Illinois

Dawes Fretzin Clinical Research Group, LLC, Indianapolis, Indiana

Lawrence J Green, MD LLC, Rockville, Maryland

Henry Ford Health System, Detroit, Michigan

JDR Dermatology Research, LLC, Las Vegas, Nevada

Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire

Markowitz Medical PLLC dba OptiSkin Medical, New York, New York

University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

Bexley Dermatology Research - Probity - PPDS, Bexley, Ohio

Apex Clinical Research Center, LLC - Canton, Canton, Ohio

Apex Clinical Research Center, LLC - Mayfield Heights, Mayfield Heights, Ohio

UPMC Department of Dermatology, Pittsburgh, Pennsylvania

Goodlettsville Dermatology Research, Goodlettsville, Tennessee

Arlington Research Center, Arlington, Texas

Bellaire Dermatology Associates, Bellaire, Texas

The University of Texas Health Science Center at Houston (UTHSC-H), Bellaire, Texas

Reveal Research Institute, Dallas, Texas

San Antonio, San Antonio, Texas

Texas Dermatology and Laser Specialists-San Antonio, San Antonio, Texas

Houston Center for Clinical Research, LLC, Sugar Land, Texas

Medical Centre Femiclinic EOOD, Sofia, Dianabad District

Medical Center Unimed EOOD-Sevlievo, Sevlievo, Gabrovo

Medical Center Asklepii OOD, Dupnitsa, Kjustendil

Diagnostic and Consulting Center Aleksandrovska EOOD, Sofia, Sofia-Grad

Medical Center Hera EOOD-Sofia, Sofia, Sofia-Grad

Diagnostic Consultative Center XXVIII - Sofia - EOOD, Sofia, Sofia-Grad

Military Medical Academy Multiprofile Hospital for Active Treatment - Sofia, Sofia, Sofia-Grad

Multiprofile Hospital For Active Treatment Dr Tota Venkova, Gabrovo, Not set

Diagnostic Consultative Center Sveti Georgi EOOD, Haskovo, Not set

Medical Center Medconsult Pleven - Lovech Branch, Lovech, Not set

Beacon Dermatology - Probity, Calgary, Alberta

VIDA Dermatology - Probity, Edmonton, Alberta

Enverus Medical Research - Probity, Surrey, British Columbia

Dr Chih-Ho Hong Medical Inc, Surrey, British Columbia

Wiseman Dermatology Research Inc., Winnipeg, Manitoba

Brunswick Dermatology Centre - Probity, Fredericton, New Brunswick

Lima's Excellence In Allergy And Dermatology Research (Leader) Inc. - Probity, Hamilton, Ontario

Dermatrials Research, Hamilton, Ontario

Lynderm Research Inc - Probity, Markham, Ontario

North Bay Dermatology Center - Probity, North Bay, Ontario

The Centre for Clinical Trials Inc., Oakville, Ontario

Skin Centre for Dermatology, Peterborough, Ontario

The Centre For Dermatology, Richmond Hill, Ontario

Alliance Clinical Trials, Waterloo, Ontario

XLR8 Medical Research, Windsor, Ontario

Siena Medical Research Corporation, Montreal, Quebec

Skinsense Medical Research, Saskatoon, Saskatchewan

Centre de Recherche Dermatologique du Quebec Metropolitain, Quebec, Not set

Pratia Brno s.r.o. - PRATIA - PPDS, Brno, Jihomoravský Kraj

Nemocnice AGEL Novy Jicin a.s, Nový Jičín, Moravskoslezský Kraj

CCR Ostrava s.r.o., Ostrava, Moravskoslezský Kraj

Dermskin s.r.o, Olomouc, Olomoucký Kraj

Pratia Pardubice, Pardubice, Not set

Praglandia s.r.o., Prague, Not set

CLINTRIAL s.r.o., Praha 10, Not set

Prof. MUDr. Petr Arenberger, DrSc. - CRC - PPDS, Praha 1, Not set

Office of Mireille Ruer-Mulard, MD, Martigues, Paca

Centre Hospitalier Le Mans, Le Mans, Sarthe

Hopital Charles Nicolle-1 Rue de Germont, Rouen, Not set

Centre Hospitalier Universitaire de Saint Etienne, Saint-etienne, Not set

Nagoya City University Hospital, Nagoya, Aichi

Fukuoka University Hospital, Fukuoka-shi, Fukuoka-Ken

Hino Dermatology Clinic, Fukutsu-shi, Fukuoka

JR Sapporo Hospital, Sapporo-shi, Hokkaido

Investigational Product department, Sapporo, Hokkaido

Nippon Life Hospital, Osaka-Shi, Osaka

Investigational Product department Dermatology and Ophthalmology Kume Clinic, Sakai-shi, Osaka

Seikoukai Omi Medical Center, Kusatsu-shi, Shiga

Jichi Medical University Hospital, Shimotsuke-shi, Tochigi

JCHO Tokyo Yamate Medical Center, Shinjuku-ku, Tokyo-to

St. Luke's International Hospital, Chuo-ku, Tokyo

Tokyo Medical University Hospital, Shinjuku-Ku, Tokyo

Medical Corporation Jitai-kai Tachikawa Dermatology Clinic, Tachikawa-shi, Tokyo

Shirasaki Dermatology Clinic, Takaoka-shi, Toyama

Ohyama Dermatology Clinic, Kumamoto, Not set

Semigallia, Kuldīga, Not set

Health Center 4, Center of Diagnostics, Riga, Not set

Health Center 4, Clinic of Dermatology, Riga, Not set

Riga 1st Hospital, Riga, Not set

Aesthetic dermatology clinic of prof. J. Kisis, Riga, Not set

Veseliba un estetika Ltd., Riga, Not set

Outpatient Clinic Adoria, Riga, Not set

Dermedic Jacek Zdybski, Ostrowiec Swietokrzyski, Dolnoslaskie

Cityclinic Przychodnia lekarsko psychologiczna Matusiak sp.p, Wroclaw, Dolnoslaskie

Centrum Columbus, Wroclaw, Dolnoslaskie

DermoDent Centrum Medyczne Aldona Czajkowska Rafal Czajkowski, s.c., Osielsko, Kujawsko-Pomorskie

Centrum Terapii Współczesnej J.M. Jasnorzewska S.K.A., Lodz, Lodzkie

Dermoklinika-Centrum Medyczne s.c, Lodz, Lodzkie

Luxderm Specjalistyczny Gabinet Dermatologiczny Dorota Krasowska, Lublin, Lubelskie

Krakowskie Centrum Medyczne Sp. z o.o., Krakow, Malopolskie

Klinika Reuma Park Sp. z o.o. sp. k. | Centrum Medyczne Reuma Park, Warszawa, Masovian

Klinika Ambroziak Dermatologia, Warsaw, Mazowieckie

MICS Centrum Medyczne Warszawa, Warszawa, Mazowieckie

ETG Warszawa - PPDS, Warszawa, Mazowieckie

Uniwersytecki Szpital Kliniczny im. Fryderyka Chopina w Rzeszowie, Rzeszow, Podkarpackie

ClinicMed Daniluk, Nowak Spolka Komandytowa, Białystok, Podlaskie

Centrum Badan Klinicznych Pi-house Sp. Z O. O., Gdansk, Pomorskie

Ambulatorium Sp. z o.o. | Elblag, Poland, Elbląg, Warmian-Masurian

NZOZ Holsamed-Oddział Libero, Katowice, Not set

ETYKA Osrodek Badan Klinicznych, Olsztyn, Not set

Twoja Przychodnia - Szczecinskie Centrum Medyczne, Szczecin, Not set

Royalderm Agnieszka Nawrocka, Warszawa, Not set

Conditions: Plaque Psoriasis

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Fixed Duration vs Continuous Daratumumab in Transplant Ineligible Older Adults With Newly Diagnosed Multiple Myeloma

NCT06182774

Recruiting

Currently, daratumumab, lenalidomide, and dexamethasone are given continuously (non-stop). Some recent observations suggest that stopping daratumumab after about a year and a half of treatment may work just as well as giving it continuously with lenalidomide and dexamethasone. This study is being done to answer the question: is less daratumumab treatment as good as more?

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/11/2025

Locations: BCCA - Kelowna, Kelowna, British Columbia +25 locations

BCCA - Kelowna, Kelowna, British Columbia

BCCA - Vancouver, Vancouver, British Columbia

CancerCare Manitoba, Winnipeg, Manitoba

The Moncton Hospital, Moncton, New Brunswick

Regional Health Authority B, Zone 2, Saint John, New Brunswick

Dr. H. Bliss Murphy Cancer Centre, St. John's, Newfoundland and Labrador

Royal Victoria Regional Health Centre, Barrie, Ontario

William Osler Health System, Brampton, Ontario

Juravinski Cancer Centre at Hamilton Health Sciences, Hamilton, Ontario

Kingston Health Sciences Centre, Kingston, Ontario

Waterloo Regional Health Network (WRHN), Kitchener, Ontario

London Health Sciences Centre Research Inc., London, Ontario

Stronach Regional Health Centre at Southlake, Newmarket, Ontario

Lakeridge Health Oshawa, Oshawa, Ontario

Ottawa Hospital Research Institute, Ottawa, Ontario

Algoma District Cancer Program, Sault Ste. Marie, Ontario

Niagara Health System, St. Catharines, Ontario

St. Michael's Hospital, Toronto, Ontario

St. Joseph's Health Centre, Toronto, Ontario

Windsor Regional Cancer Centre, Windsor, Ontario

CIUSSS de l'Est-de-I'lle-de-Montreal, Montreal, Quebec

The Jewish General Hospital, Montreal, Quebec

The Research Institute of the McGill University, Montreal, Quebec

CHU de Quebec-Hopital l'Enfant-Jesus (HEJ), Quebec City, Quebec

Allan Blair Cancer Centre, Regina, Saskatchewan

Saskatoon Cancer Centre, Saskatoon, Saskatchewan

Conditions: Multiple Myeloma

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Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER

NCT05640999

Recruiting

This protocol tests de-escalated adjuvant treatment in patients with POLE-mutated or p53wt/NSMP (p53 wildtype/no specific molecular profile) early-stage endometrial cancer (EC). Patients may be enrolled in one of two sub-studies * EN10.A/RAINBO BLUE: POLE-mutated EC * EN10.B/TAPER: p53 wildtype / NSMP EC

Gender:

FEMALE

Ages:

18 years and above

Trial Updated:

08/11/2025

Locations: Alaska Womens Cancer Care, Anchorage, Alaska +76 locations

Alaska Womens Cancer Care, Anchorage, Alaska

University of Arizona Cancer Center, Tucson, Arizona

Cedars-Sinai Medical Center, Los Angeles, California

Huntington Memorial Hospital, Pasadena, California

Sutter Medical Center Sacramento, Sacramento, California

UCHealth University of Colorado Hospital, Aurora, Colorado

Sarasota Memorial Hospital - Venice, N. Venice, Florida

Florida Cancer Specialists - Sarasota Downtown, Sarasota, Florida

First Physicians Group-Sarasota, Sarasota, Florida

Sarasota Memorial Hospital, Sarasota, Florida

Sarasota Memorial Health Care Centre, Sarasota, Florida

Florida Cancer Specialists - Venice Pinebrook, Venice, Florida

Piedmont Hospital, Atlanta, Georgia

Northwestern University, Chicago, Illinois

Northwestern Medicine Cancer Center Warrenville, Warrenville, Illinois

Ascension Saint Vincent Indianapolis Hospital, Indianapolis, Indiana

University Medical Center New Orleans, New Orleans, Louisiana

UMass Memorial Medical Centre, Worcester, Massachusetts

Washington University School of Medicine, Saint Louis, Missouri

Womens Cancer Center of Nevada, Las Vegas, Nevada

Sidney Kimmel Cancer Center Washington Township, Sewell, New Jersey

Mount Sinai Chelsea, New York, New York

Mount Sinai Hospital, New York, New York

Upstate Cancer Center Radiation Oncology at Oswego, Oswego, New York

State University of New York, Syracuse, New York

Upstate Cancer Center at Hill Radiation Oncology, Syracuse, New York

Upstate Cancer Center at Verona, Verona, New York

UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina

Duke University Medical Center, Durham, North Carolina

Duke Womens Cancer Care Raleigh, Raleigh, North Carolina

Case Western Reserve University, Cleveland, Ohio

Ohio State University Comprehensive, Columbus, Ohio

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Providence Portland Medical Centre, Portland, Oregon

Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania

Thomas Jefferson University, Philadelphia, Pennsylvania

Asplundh Cancer Pavilion, Willow Grove, Pennsylvania

Women and Infants Hospital, Providence, Rhode Island

Farmington Health Centre, Farmington, Utah

University of Utah Sugarhouse Health Centre, Salt Lake City, Utah

Huntsman Cancer Institute University of Utah, Salt Lake City, Utah

University of Virginia Cancer Center, Charlottesville, Virginia

Virginia Commonwealth University, Richmond, Virginia

Medical College of Wisconsin, Milwaukee, Wisconsin

South Western Sydney Local Health District, Liverpool, New South Wales

Calvary Mater Newcastle Hospital, Waratah, New South Wales

Westmead Hospital, Westmead, New South Wales

Mater Research Institute South Brisbane, South Brisbane, Queensland

Monash Medical Centre, Clayton, Victoria

Frankston Hospital, Frankston, Victoria

The Royal Women's Hospital, Parkville, Victoria

Canberra Hospital, Garran, Not set

Royal Brisbane and Womens Hospital, Herston, Not set

Arthur J.E. Child Comprehensive Cancer Centre, Calgary, Alberta

Cross Cancer Institute, Edmonton, Alberta

BCCA - Kelowna, Kelowna, British Columbia

BCCA - Prince George, Prince George, British Columbia

BCCA - Vancouver, Vancouver, British Columbia

BCCA - Victoria, Victoria, British Columbia

London Health Sciences Centre Research Inc., London, Ontario

Trillium Health Partners - Credit Valley Hospital, Mississauga, Ontario

Odette Cancer Centre, Toronto, Ontario

University Health Network, Toronto, Ontario

CHUM-Centre Hospitalier de l'Universite de Montreal, Montreal, Quebec

The Jewish General Hospital, Montreal, Quebec

CIUSSS de l'Estrie - Centre hospitalier, Sherbrooke, Quebec

Institut Gustave-Roussy, Villejuif, FR

Institut Universitaire du Cancer de Toulouse - IUCT, Toulouse, Occitanie

European Institute of Oncology, Milan, Not set

Radiotherapiegroep, Arnhem, Gelderland

Maastro clinic (Maastricht UMC), Maastricht, Limburg

Catharina ziekenhuis, Eindhoven, Noord Brabant

MC Haaglanden, Den Haag, South Holland

Leiden University Medical Center (LUMC), Leiden, Not set

Erasmus Medical Center (EMC), Rotterdam, Not set

Auckland City Hospital, Auckland, Not set

Christchurch Hospital, Christchurch, Not set

Conditions: Endometrial Cancer

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Smartphone App-Based Mindfulness Intervention for French and English Speaker Cancer Survivors

NCT05470010

Recruiting

There is a need to develop, evaluate, and disseminate self-directed, easily accessible, safe, affordable, and effective psychosocial interventions to people living with cancer (PLWC) post-treatment. Smartphone app-based health interventions are an innovative way to deliver psychosocial cancer-care. The Mindfulness-Based Cancer Survivorship (MBCS) Journey app is a mobile app format of the Mindfulness-based Cancer Recovery program. In the SEAMLESS Study, the investigators aim to evaluate the MBCS... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/11/2025

Locations: Arthur J.E. Child Comprehensive Cancer Centre, Calgary, Alberta +6 locations

Conditions: Cancer, Psychological

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Type 1 Diabetes Virtual Self-management Education and Support

NCT05756829

Recruiting

OVERVIEW: People living with type 1 diabetes (T1D) are expected to fit self-management and regular clinical consultations into busy lives. T1D self-management programs that offer frequent contact with care teams are most effective in helping patients achieve optimal glycemic control. However, this is difficult to deliver in the context of current T1D care which involves time-consuming in-person visits during working hours. The proposed study will test a virtual health care intervention to delive... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/11/2025

Locations: Waterloo Regional Health Network, Kitchener, Ontario +6 locations

Conditions: type1diabetes

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A Research Study to Look at Long-term Treatment With a Medicine Called NNC6019-0001 for People Who Have Heart Failure Due to Transthyretin Amyloidosis

NCT06260709

Recruiting

This study will test a medicine, NNC6019-0001, for people who have a heart disease due to TTR amyloidosis. It will look at how safe this medicine is in the long term and if it can reduce symptoms of a heart disease due to TTR amyloidosis, such as heart failure. It is an extension to a study called "A research study to look at how a new medicine called NNC6019-0001 works and how safe it is for people who have a heart disease due to TTR amyloidosis". Only participants who have completed that study... Read More

Gender:

ALL

Ages:

Between 18 years and 85 years

Trial Updated:

08/10/2025

Locations: Mayo Clinic Arizona, Phoenix, Arizona +49 locations

Mayo Clinic Arizona, Phoenix, Arizona

Cedars-Sinai Medical Center_Los Angeles, Los Angeles, California

Stanford Hlth Cre-Boswell Clin, Stanford, California

Mayo Clinic Jacksonville, Jacksonville, Florida

NW Univ-Bluhm Cardiovasc Inst, Chicago, Illinois

NW Univ-Bluhm Cardiovasc Inst, Evanston, Illinois

Univ of MD Schl of Med, Baltimore, Maryland

Mayo Clinic Rochester, Rochester, Minnesota

University of Calgary_Cardiology, Calgary, Alberta

Ctr for Cardiovascular Innovation, Vancouver, British Columbia

II. interni klinika VFN - Kardiologie a angiologie, Praha 2, Not set

Ap-Hp-Hopital Henri Mondor, Créteil, Not set

Centre Hospitalier Universitaire de Toulouse-Hopital Rangueil-1, Toulouse Cedex 9, Not set

UniklinikHeidelberg - Innere Med. III - Kardiologie, Angiologie, Pneumologie, Heidelberg, Not set

Universitätsklinik Heidelberg Innere Medizin III Kardiologie, Angiologie, Pneumologie, Heidelberg, Not set

LMU Klinikum München Klinik und Poliklinik 1, München, Not set

Uniklinik Münster, Klinik für Kardiologie I, Münster, Not set

Universitätsklinikum Münster - Klinik für Kardiologie I, Münster, Not set

Universitatsklinikum Wurzburg AöR, Würzburg, Not set

Universitatsklinikum Würzburg - Zentrum für Herzinsuffizienz, Würzburg, Not set

Fondazione CNR-Regione Toscana Gabriele Monasterio, Pisa, Pi

Centro per lo Studio e la Cura delle Amiloidosi Sistemiche Fondazione IRCCS Policlinico San Matteo, Pavia, PV

Hospital of the University of Occupational and Environmental Health, Cardiology, Nephrology, Fukuoka, Not set

Hiroshima University hospital, Cardiovascular Medicine, Hiroshima, Not set

Kumamoto University Hospital, Cardiovascular Medicine, Kumamoto-shi, Kumamoto, Not set

Shinshu University Hospital, Department of Neurology, Nagano, Not set

Nagasaki University Hospital, Cardiovascular Medicine, Nagasaki, Not set

Okayama University Hospital_Cardiovascular Medicine, Okayama-shi, Okayama, Not set

UMC Groningen, Groningen, Not set

Universitair Medisch Centrum Utrecht, Utrecht, Not set

Hospital da Senhora da Oliveira - Guimarães, Guimarães, Not set

Unidade Local de Saude do Alto Ave, E.P.E., Guimarães, Not set

Centro Hospitalar de Trás-os-Montes e Alto Douro, Vila Real, Not set

Unidade Local De Saude De Tras-Os-Montes E Alto Douro E.P.E., Vila Real, Not set

Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda, Madrid

Conditions: Transthyretin Amyloid Cardiomyopathy (ATTR CM)

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A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy

NCT06979362

Recruiting

This study will look into how CDR132L (a potential new medicine) works on the structure and function of the heart in people living with heart failure. Participants will either get CDR132L or placebo (a medicine which has no effect on the body), which treatment the participants get is decided by chance. The study will last for about 60 weeks.

Gender:

ALL

Ages:

Between 40 years and 84 years

Trial Updated:

08/10/2025

Locations: Univ of Alabama Birmingham, Birmingham, Alabama +90 locations

Univ of Alabama Birmingham, Birmingham, Alabama

Pima Heart and Vascular, Tucson, Arizona

Valley Clinical Trials, Covina, California

UCSD NAFLD Research Center, La Jolla, California

Valley Clinical Trials, Northridge, California

University of California, San Francisco, San Francisco, California

University of California San Francisco UCSF, San Francisco, California

Harbor-UCLA Medical Center, Torrance, California

CPC Clinical Research & Community Health, Aurora, Colorado

Inpatient Research Clinic LLC, Miami Lakes, Florida

AdventHealth Orlando, Orlando, Florida

UofL Health Care Outpatient, Louisville, Kentucky

Henry Ford Hospital, Detroit, Michigan

University of Minnesota_Minneapolis_1, Minneapolis, Minnesota

Washington University School of Medicine, Saint Louis, Missouri

Icahn Sch of Med-Mt Sinai Hosp, New York, New York

Duke University_Durham, Durham, North Carolina

Providence St. Vincent Heart, Portland, Oregon

Abington Memorial Hospital, Abington, Pennsylvania

Capital Area Research LLC, Camp Hill, Pennsylvania

Vanderbilt University Medical Center, Nashville, Tennessee

Amarillo Medical Specialists, Amarillo, Texas

University of Texas Southwestern Medical Center, Dallas, Texas

Texama Medical Center, Denison, Texas

East Texas Cardiology PA, Houston, Texas

Inova Heart and Vascular Institute, Falls Church, Virginia

Sentara Bayside Hospital, Norfolk, Virginia

St Pauls Hospital, Vancouver, British Columbia

Hamilton Hlth Sc. - General Site, Hamilton, Ontario

Hamilton General Hospital, Hamilton, Ontario

Cardio Health Clinical Trials, Mississauga, Ontario

University of Ottawa Heart Ins, Ottawa, Ontario

St. Michael's Hospital, Toronto, Ontario

Women's College Hospital, Toronto, Ontario

Winchester Dist Memorial Hosp, Winchester, Ontario

Sana Kliniken Berlin-Brandenburg GmbH - Lichtenberg, Berlin, Not set

Charité - Campus Benjamin Franklin - Klinik für Kardiologie, Berlin, Not set

Uniklinik TU Dresden - Herzzentrum Dresden GmbH, Dresden, Not set

Universitaetsklinikum Essen - Klinik für Kardiologie und Angiologie, Essen, Not set

Universitätsklinikum Frankfurt aM - Kardiologie, Frankfurt am Main, Not set

Universitätsklinikum Halle - Innere Medizin III, Halle (Saale), Not set

Medizinische Hochschule Hannover - Kardiologie und Angiologie, Hannover, Not set

UniklinikHeidelberg - Innere Med. III - Kardiologie, Angiologie, Pneumologie, Heidelberg, Not set

Universitätsklinikum Schleswig-Holstein - Med. Klinik III Kardiologie und Internist. Intensivmedizin, Kiel, Not set

G B Pant Institute of Postgraduate Medical Education and Research, New Delhi, Delhi

Rhythm Heart Institute - A unit of Synergy Lifecare Pvt, Vadodara, Gujarat

Sengupta Hospital and Research Institute, Nagpur, Maharashtra

All India Institute of Medical Sciences (AIIMS), Nagpur, Nagpur, Maharashtra

VMMC & Safdarjung Hospital, New Dehli, New Delhi

Apollo Hospital Chennai, Chennai, Tamil Nadu

Osmania General Hospital, Hyderabad, Telangana

IPGME&R and SSKM Hospital, Kolkata, West Bengal

Sir Ganga Ram Hospital-Cardiology, New Delhi, Not set

NIPPON MEDICAL SCHOOL HOSPITAL_Cardiovascular medicine, Bunkyo-ku, Tokyo, Not set

Hyogo Prefectural HarimaHimeji General Medical Center_Cardiology, Himeji-shi, Hyogo, Not set

National Hospital Organization Mito Medical Center_Cardiovascular medicine, Ibaraki, Not set

Yokohama City University Medical Center_Cardiovascular Center, Kanagawa, Not set

Kagawa University Hospital_Cardiology, Kita-gun, Kagawa, Not set

Kobe City Medical Center General Hospital_Cardiology, Kobe-shi, Hyogo, Not set

Medical Research Institute KITANO HOSPITAL_Cardiovascular Medicine, Osaka-shi, Osaka, Not set

Osaka Metropolitan University Hospital_Cardiovascular Medicine, Osaka-Shi, Osaka, Not set

Sapporo Medical University Hospital_Cardiovascular, Kidney, Metabolism Endocrinology, Sapporo-shi, Hokkaido, Not set

National Hospital Organization Yokohama Medical Center_Cardiology, Yokohama-shi, Kanagawa, Not set

Chungbuk National University Hospital, Cheongju, Not set

Keimyung University Dongsan Hospital, Daegu, Not set

Wonju Severance Christian Hospital, Gangwon-do, Not set

Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Not set

Korea University Anam Hospital, Seoul, Not set

Korea University Guro Hospital, Seoul, Not set

4 Wojskowy Szpital Kliniczny Z Poliklinika Samodzielny Publiczny Zaklad Opieki Zdrowotnej We Wroclawiu, Wroclaw, Dolnoslaskie

Uniwersytecki Szpital Kliniczny w Bialymstoku, Białystok, Podlaskie

American Heart of Poland S.A., Bielsko-Biała, Not set

Krakowski Szpital Specjalistyczny im. Jana Pawła II, Krakow, Not set

Szpital Specjalistyczny im. Ludwika Rydygiera w Krakowie Sp. z o.o., Kraków, Not set

Uniwersytecki Szpital Kliniczny Nr 4 W Lublinie, Lublin, Not set

Wojewodzki Szpital Im. Sw.Ojca Pio W Przemyslu, Przemysl, Not set

Narodowy Instytut Kardiologii Stefana Kardynala Wyszynskiego Panstwowy Instytut Badawczy, Warsaw, Not set

Uniwersytecki Szpital Kliniczny Im. Jana Mikulicza-Radeckiego We Wroclawiu, Wroclaw, Not set

Hospital Universitario San Cecilio, Granada, Andalucía

Hospital Univ. Virgen de la Arrixaca, El Palmar, Murcia

Hospital del Mar, Barcelona, Not set

Hospital Universitario La Paz, Madrid, Not set

Hospital Clinico Universitario de Valencia, Valencia, Not set

Trialmed - Midlands, Birmingham, Not set

Wycombe General Hospital, High Wycombe, Not set

Kings College Hospital, London, Not set

The Royal Brompton Hospital - Cardiovascular Research Centre/Respiratory CRF, London, Not set

The James Cook University Hospital, Middlesbrough, Not set

Southampton General Hospital, Southampton, Not set

Conditions: Heart Failure

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A Research Study Comparing How Well Different Doses of the Medicine NN0519-0130 Lower Blood Sugar in People With Type 2 Diabetes

NCT06326047

Recruiting

This study will look at how well a new medicine called NNC0519-0130 helps people with type 2 diabetes lower their blood sugar and body weight. The study will test up to 7 different doses of NNC0519-0130. Which treatment participant will get is decided by chance. Participants will take 1-3 injections once a week. The study medicine will be injected under skin with a thin needle in the stomach, thigh, or upper arm. The study will last for about 40 weeks.

Gender:

ALL

Ages:

Between 18 years and 75 years

Trial Updated:

08/10/2025

Locations: Velocity Clin Res-Chula Vista, Chula Vista, California +114 locations

Velocity Clin Res-Chula Vista, Chula Vista, California

Valley Research, Fresno, California

310 Clinical Research, Inglewood, California

Velocity Clin Res San Diego, La Mesa, California

First Valley Med Grp Lancaster, Lancaster, California

Torrance Clin Res Inst, Inc., Lomita, California

Pacific Clinical Studies, Los Alamitos, California

Catalina Research Institute, LLC, Montclair, California

Med Partners, Inc., Toluca Lake, California

UCLA Health Southbay Endocrine, Torrance, California

University Clin Investigators, Tustin, California

Diablo Clinical Research, Inc., Walnut Creek, California

University of Colorado Hospital, Aurora, Colorado

Innovative Research of W Florida Inc., Clearwater, Florida

Innovative Research of W FL, Clearwater, Florida

International Research Associates, LLC_Miami, Miami, Florida

Centricity Research, Columbus, Georgia

Elite Clinical Trials, Blackfoot, Idaho

Methodist Medical Center of Illinois, Peoria, Illinois

Centennial Medical Group, Columbia, Maryland

MD Medical Research, Oxon Hill, Maryland

Endo And Metab Cons, Rockville, Maryland

Clinvest Research, Springfield, Missouri

Mercury Str Med Grp, PLLC, Butte, Montana

Excel Clinical Network, Las Vegas, Nevada

Palm Research Center Inc-Vegas, Las Vegas, Nevada

Velocity Clinical Research Binghamton, Binghamton, New York

PharmQuest Life Sciences LLC, Greensboro, North Carolina

Accellacare Wilmington, Wilmington, North Carolina

Diab & Endo Assoc of Stark Co, Canton, Ohio

Velocity Clin Res_Cincinnati, Cincinnati, Ohio

Velocity Clinical Research Springdale, Cincinnati, Ohio

Providence Health Partners Ctr, Dayton, Ohio

Advanced Med Res Maumee, Maumee, Ohio

Tristar Clin Investigations, PC, Philadelphia, Pennsylvania

Preferred Primary Care Physicians Inc., Pittsburgh, Pennsylvania

Preferred Primary Care Physicians, Inc., Uniontown, Pennsylvania

Velocity Clinical Research Abilene, Abilene, Texas

Velocity Clin Res Austin, Austin, Texas

Velocity Clinical Res-Dallas, Dallas, Texas

Zenos Clinical research, Dallas, Texas

Care United Research, LLC, Forney, Texas

Endocrine Associates Houston, Houston, Texas

Biopharma Informatic_Houston, Houston, Texas

Tekton Research, Irving, Texas

Epic Clinical Research, Lewisville, Texas

Consano Clinical Research, LLC, Shavano Park, Texas

Burke Internal Medicine & Research, Burke, Virginia

TPMG Clinical Research, Newport News, Virginia

Macquarie University, Macquarie Park, New South Wales

Royal North Shore Hospital, St Leonards, New South Wales

Roger Chih Yu Chen, Sydney, New South Wales

Western Endocrine Blacktown, Sydney, New South Wales

Illawarra Diabetes Service Clinical Trials & Research Unit, Wollongong, New South Wales

University of Sunshine Coast, Birtinya, Queensland

Eastern Clinical Research Unit Box Hill, Box Hill, Victoria

Emeritus Research Melbourne, Camberwell, Victoria

Austin Health, Metabolic Disorders Centre, Heidelberg Heights, Victoria

The Royal Melbourne Hospital, Parkville, Victoria

OCT Research ULC (dba Okanagan Clinical Trials), Kelowna, British Columbia

OCT Research ULC (dba Okanagan Clinical Trials), Richmond, British Columbia

Cook Street Medical Clinic, Victoria, British Columbia

G.A. Research Associates Ltd., Moncton, New Brunswick

Nova Scotia Hlth Halifax, Halifax, Nova Scotia

Wharton Med Clin Trials, Hamilton, Ontario

Albion Finch Medical Centre, Toronto, Ontario

Centricity Research Quebec City, Levis, Quebec

Recherche GCP Research, Montreal, Quebec

Centricity Research Ville St. Laurent VSL, Ville Saint-Laurent, Quebec

Diex Recherche Quebec Inc., Quebec, Not set

Life Care Hospital and Research Centre, Bangalore, Karnataka

Amrita Institute Of Medical Sciences & Research Centre, Kochi, Kerala

TOTALL Diabetes Hormone Institute, Indore, Madhya Pradesh

Seth GS Medical College & KEM Hospital, Mumbai, Maharashtra

Chellaram Diabetes Institute, Pune, Maharashtra

Diabetes, Thyroid and Endocrine Centre, Jaipur, Rajasthan

Christian Medical College Hospital, Vellore, Vellore, Tamil Nadu

Diabetes Research Center, Hyderabad, Hyderabad, Telangana

MS Ramaiah, Bengaluru, Not set

Tokuyama clinic_Diabetic internal medicine, Chiba, Not set

Soka Sugiura Internal Medicine Clinic, Soka-shi, Saitama, Not set

Tokyo-Eki Center-building Clinic_Internal Medicine, Tokyo, Not set

Fukuwa Clinic_Internal Medicine, Tokyo, Not set

Fukuwa Clinic, Tokyo, Not set

Seoul National University Bundang Hospital, Gyeonggi-do, Not set

Nowon Eulji Medical Center, Eulji University, Seoul, Not set

Korea University Anam Hospital, Seoul, Not set

Kangbuk Samsung Hospital, Seoul, Not set

Asan Medical Center, Seoul, Not set

Josha Research, Bloemfontein, Free State

Wits Bara Clinical Trial Site, Johannesburg, Gauteng

Shop#1 Health Emporium, Midrand, Gauteng

Dr Pillay's Rooms, Durban, KwaZulu-Natal

Dr T Padayachee, Umkomaas, KwaZulu-Natal

Conditions: Diabetes Mellitus, Type 2

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