All Clinical Trials in Canada

A listing of 3905 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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Metabolic and Behavioural Effects of CONTRAVE as Potential Mechanisms of Weight Loss in Adults With Obesity

NCT06809166

Recruiting

Obesity is a common chronic disease linked with increased risk for other illnesses and earlier death. Our team and others have shown that many bodily and psychological changes occur when individuals are on calorie-restricted diets. These changes might undermine dietary adherence and help to explain the relatively poor long-term efficacy of diets. These include increased appetite, increased food 'value' and 'wanting' that leads to overconsumption. Other factors include more sensitive sensory cues (e.g., smelling), higher food liking and craving, and a drop in resting energy expenditure (REE). REE has been shown to predict weight regain. The standard care for obesity may include the use of the weight-loss drug CONTRAVE®. The Federal Drug Agency (FDA) and Health Canada have approved this drug for weight management and obesity treatment. Although CONTRAVE® was designed to reduce appetite, food-related impulsivity and cravings, its mechanisms of action are unclear. In other words, the effects of CONTRAVE® on REE, executive function, and brain changes remain unknown in humans. A better understanding of how this drug works on the brain and body could lead to improvements in obesity management in the future. As such, the goal of this research is to study the effects of 4 weeks of CONTRAVE® (+ diet program) vs. control (placebo pill + diet program) on mood, body composition changes, biological/metabolic measures, and brain measures. Adults aged 18-64 with obesity will be randomized to one of two groups: diet + CONTRAVE® (CONTRAVE®, 20 participants) or diet + Placebo (Placebo, 20 participants). Both groups will be assigned the same study procedures for the entire study duration. The only difference is that Group 1 will receive CONTRAVE® while Group 2 will receive a placebo (non-medical) pill. The study design and intervention is as follows: Participants who meet all the telephone screening criteria will be invited to the Clinical EEG \& Neuroimaging Laboratory at The Royal's IMHR for an in-person screening and test-dose session. Participants who are cleared by the study physician, Dr. Pierre Blier, during the in-person screening will be enrolled in the 4-weeks trial. After the in-person screening visit, participants will attend two baseline testing visits (before starting the medication + diet program). The first will occur at the Behavioural and Metabolic Research Unit at the University of Ottawa. During this in-person visit, measures of body composition, resting energy expenditure, appetite, food craving, impulsivity, eating behaviours, taste and odour sensitivity, energy intake, and food preference will be collected. The second baseline visit (within a week of the first one) will occur at The Royal/IMHR. During this visit, participants will be asked to complete questionnaires. They will undergo an EEG recording while resting and performing computer tasks. They will also get a brain imaging scan, during which they are asked to rest and complete a computer task. Both testing sessions (University of Ottawa and Royal Ottawa testing sessions) will be repeated after four weeks of treatment. The section below provides further description and timing of these visits. As part of the treatment, you will receive an individualized dietary intervention with appropriate energy restriction from a registered dietitian at Dr. Judy Shiau's LEAF weight management clinic (called the 4-week BUDS program). The program involves weekly touch points with a registered dietitian and meal planning/coaching. The diet intervention will commence the same week as the start of the placebo/CONTRAVE®. During the 4-week intervention, participants will be asked to complete online questionnaires at various times. Read Less

Gender:

ALL

Ages:

Between 18 years and 64 years

Trial Updated:

07/21/2025

Locations: LEAF Weight Managment Clinic, Ottawa, Ontario +2 locations

Conditions: Obesity, Weight Loss, Weight Management, Dietary Intervention, Obesity/therapy

Learn More ›

ELIOS - Investigational Biomarkers to Track Disease Modification in Active RRMS

NCT06733922

Recruiting

The exploratory ELIOS study aims to assess the value of novel investigational Eye Movement Biomarkers (EMBs) in tracking disease-related changes among a real-world cohort of Canadian patients with active RRMS, within the context of disease-modifying treatment (i.e., ofatumumab). To that end, the study will use the patented investigational, Eye Tracking Neurological Assessment (ETNA-ProgMS) SaMD (v1.0.11 or later), which has not yet received Health Canada approval, to reliably and accurately trac... Read More

Gender:

ALL

Ages:

Between 18 years and 99 years

Trial Updated:

07/21/2025

Locations: Novartis Investigative Site, Halifax, Nova Scotia +4 locations

Conditions: Relapsing Remitting Multiple Sclerosis (RRMS)

Learn More ›

Novel Pulmonary Function Measures for Diagnosis of Bronchiolitis Obliterans Syndrome Following Hematopoietic Stem-Cell Transplantation in Children

NCT04391335

Recruiting

In this study, we will study 129Xe-MRI and LCI as tools for diagnosis of BOS in pediatric patients who have received Hematopoietic Stem Cell Transplantation (HSCT) and have been identified as eligible for this study. Participants will be required to have vital signs collected, complete breathing tests and complete an MRI. The MRI will require participants to perform breath holds in the MRI scanner with xenon gas while being coached by a research assistant.

Gender:

ALL

Ages:

Between 6 years and 18 years

Trial Updated:

07/21/2025

Locations: The Hospital for Sick Children, Toronto, Ontario

Conditions: Bronchiolitis Obliterans Syndrome

Learn More ›

Comparing No Mechanical Bowel Preparation With Oral Antibiotics Alone in Patients Undergoing Elective Colon Surgery

NCT03663504

Recruiting

The REaCT NSQIP will compare oral antibiotics vs. no antibiotics, which are two standards of care treatments for preoperative preparation of the bowel prior to colorectal surgery

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/21/2025

Locations: The Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia +6 locations

Conditions: Elective Colon Surgery

Learn More ›

Oral Sildenafil for Exercise Capacity, Dyspnea and Cardiopulmonary Function in COPD

NCT05061368

Recruiting

Chronic obstructive pulmonary disease (COPD) is a condition characterized by airway obstruction. Patients with COPD experience significant shortness of breath on exertion. The mechanisms responsible for shortness of breath on exertion are well understood in moderate and severe COPD, but, are poorly understood in mild COPD where symptoms appear disproportionate to the degree of airway obstruction. Mild COPD patients show an exaggerated breathing response to exercise, determined by the breathing... Read More

Gender:

ALL

Ages:

Between 40 years and 80 years

Trial Updated:

07/21/2025

Locations: Clinical Physiology Laboratory, Edmonton, Alberta

Conditions: Chronic Obstructive Pulmonary Disease

Learn More ›

Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer

NCT05445778

Recruiting

GLORIOSA is a Phase 3 multicenter, open label study designed to evaluate the safety and efficacy of mirvetuximab Soravtansine + Bevacizumab as maintenance therapy in participants with platinum-sensitive ovarian, primary peritoneal or fallopian tube cancers with high folate receptor-alpha (FRα) expression.

Gender:

FEMALE

Ages:

18 years and above

Trial Updated:

07/21/2025

Locations: Usa Mitchell Cancer Institute /ID# 269661, Mobile, Alabama +239 locations

Usa Mitchell Cancer Institute /ID# 269661, Mobile, Alabama

Honorhealth Virginia G. Piper Cancer Care Network - Biltmore /ID# 269987, Phoenix, Arizona

City of Hope Orange County Lennar Foundation Cancer Center /ID# 269573, Irvine, California

Moores Cancer Center at UC San Diego /ID# 269564, La Jolla, California

University Of California Irvine Medical Center /ID# 269572, Orange, California

Stanford Women'S Cancer Center /ID# 269552, Palo Alto, California

Kaiser Permanente Zion Medical Center /ID# 269537, San Diego, California

Kaiser Permanente - San Diego Medical Center /ID# 269540, San Diego, California

Kaiser Permanente - San Marcos Medical Offices /ID# 269542, San Marcos, California

Olive View-Ucla Medical Center /ID# 269584, Sylmar, California

John Muir Health - Walnut Creek Medical Center /ID# 269575, Walnut Creek, California

Broward General Medical Center /ID# 269577, Fort Lauderdale, Florida

Regional Cancer Center /ID# 269558, Fort Myers, Florida

Baptist Md Anderson Cancer Center - Jacksonville - Palm Avenue /ID# 269560, Jacksonville, Florida

Mount Sinai Medical Center /ID# 269582, Miami, Florida

Sarasota Memorial Hospital /ID# 269526, Sarasota, Florida

Northside Hospital /ID# 269660, Atlanta, Georgia

Rush University Medical Center /ID# 269583, Chicago, Illinois

University of Chicago Medical Center /ID# 269546, Chicago, Illinois

Indiana University Melvin and Bren Simon Comprehensive Cancer Center /ID# 269110, Indianapolis, Indiana

St. Vincent Indianapolis Hospital /ID# 269107, Indianapolis, Indiana

University of Iowa /ID# 269566, Iowa City, Iowa

The University of Kansas Cancer Center - Westwood /ID# 269106, Westwood, Kansas

Baptist Health Lexington /ID# 269568, Lexington, Kentucky

University of Kentucky Chandler Medical Center /ID# 269536, Lexington, Kentucky

Louisiana State University Health Sciences Center - New Orleans /ID# 269559, New Orleans, Louisiana

Ochsner Medical Center - Jefferson Highway /ID# 269530, New Orleans, Louisiana

Maine Medical Center - Scarborough Campus /ID# 269555, Scarborough, Maine

Johns Hopkins Hospital /ID# 269579, Baltimore, Maryland

Sinai Hospital Of Baltimore /ID# 269567, Manchester, Maryland

GBMC Cancer Center /ID# 269561, Towson, Maryland

Tufts Medical Center /ID# 269547, Boston, Massachusetts

Baystate Medical Center /ID# 269544, Springfield, Massachusetts

Corewell Health /ID# 269562, Grand Rapids, Michigan

Minnesota Oncology - Coon Rapids Clinic /ID# 269550, Coon Rapids, Minnesota

Nebraska Methodist Hospital /ID# 269580, Omaha, Nebraska

The Center Of Hope /ID# 269528, Reno, Nevada

Dartmouth-Hitchcock Medical Center - 1 Medical Center Drive /ID# 269576, Lebanon, New Hampshire

John Theurer Cancer Center /ID# 269109, Hackensack, New Jersey

The Valley Hospital /ID# 269548, Paramus, New Jersey

Holy Name Medical Center /ID# 269543, Teaneck, New Jersey

New York Oncology Hematology - Albany Cancer Center /ID# 269565, Albany, New York

Women'S Cancer Care Associates /ID# 269553, Albany, New York

Northwell Health Center for Advanced Medicine /ID# 269108, Lake Success, New York

NYU Laura and Isaac Perlmutter Cancer Center /ID# 269556, New York, New York

Icahn School of Medicine at Mount Sinai /ID# 269529, New York, New York

University of North Carolina at Chapel Hill /ID# 269563, Chapel Hill, North Carolina

Duke Cancer Institute /ID# 269557, Durham, North Carolina

University of Cincinnati /ID# 269578, Cincinnati, Ohio

The Ohio State University Comprehensive Cancer Center /ID# 269105, Columbus, Ohio

Kettering Medical Center /ID# 269585, Kettering, Ohio

Ou Health - Stephenson Cancer Center /ID# 269525, Oklahoma City, Oklahoma

Oklahoma Cancer Specialists and Research Institute /ID# 269527, Tulsa, Oklahoma

Willamette Valley Cancer Institute and Research Center /ID# 269988, Eugene, Oregon

Compass Oncology - Rose Quarter /ID# 270131, Portland, Oregon

Oregon Health and Science University /ID# 269581, Portland, Oregon

Magee-Womens Hospital of UPMC /ID# 269659, Pittsburgh, Pennsylvania

Allegheny Health Network West Penn Hospital /ID# 269551, Pittsburgh, Pennsylvania

Asplundh Cancer Pavilion /ID# 269574, Willow Grove, Pennsylvania

Sanford Cancer Center /ID# 269535, Sioux Falls, South Dakota

West Cancer Center and Research Institute - Germantown /ID# 269569, Germantown, Tennessee

Texas Oncology - Austin Central /ID# 269531, Austin, Texas

Texas Oncology - Bedford /ID# 269571, Bedford, Texas

Texas Oncology - Methodist Dallas Cancer Center /ID# 269554, Dallas, Texas

Texas Oncology - Fort Worth Cancer Center /ID# 269532, Fort Worth, Texas

Texas Oncology, P. A. /ID# 269549, San Antonio, Texas

University of Virginia Health System /ID# 269545, Charlottesville, Virginia

Virginia Oncology Associates - Norfolk (Lake Wright) /ID# 269533, Norfolk, Virginia

Vcu Health Adult Outpatient Pavillion /ID# 269570, Richmond, Virginia

Swedish Cancer Institute /ID# 269538, Seattle, Washington

Sanatorio De La Mujer /ID# 269352, Rosario, Santa Fe

Hospital Italiano de Buenos Aires /ID# 269356, Buenos Aires, Not set

Sociedad de Beneficiencia Hospital Italiano /ID# 269090, Cordoba, Not set

Isis Centro Especializado De Luce /ID# 269353, Santa Fe, Not set

Westmead Hospital /ID# 269362, Westmead, New South Wales

Gold Coast University Hospital /ID# 269365, Southport, Queensland

Ballarat Base Hospital /ID# 269364, Ballarat, Victoria

Monash Health - Monash Medical Centre /ID# 269360, Clayton, Victoria

Cabrini Hospital - Malvern /ID# 269359, Malvern, Victoria

Peter MacCallum Cancer Centre /ID# 269361, Melbourne, Victoria

Epworth Hospital /ID# 269363, Richmond, Victoria

St. John Of God Subiaco Hospital /ID# 269358, Subiaco, Western Australia

Imelda Ziekenhuis /ID# 269369, Bonheiden, Antwerpen

Cliniques Universitaires UCL Saint-Luc /ID# 269368, Bruxelles, Bruxelles-Capitale

Grand Hôpital De Charleroi - Notre Dame /ID# 269367, Charleroi, Hainaut

AZ Sint-Lucas /ID# 269366, Gent, Oost-Vlaanderen

Universitair Ziekenhuis Leuven /ID# 269370, Leuven, Vlaams-Brabant

AZ-Delta /ID# 269091, Roeselare, West-Vlaanderen

UCL Namur University Hospital, Site Sainte-Elisabeth /ID# 269371, Namur, Not set

Complex Oncology Center - Shumen /ID# 269372, Shumen, Not set

Comprehensive Cancer Center /ID# 269373, Vratsa, Not set

Arthur J. E. Child Comprehensive Cancer Centre /ID# 269388, Calgary, Alberta

Cross Cancer Institute /ID# 269392, Edmonton, Alberta

Bc Cancer Agency - Fraser Valley Centre /ID# 269398, Surrey, British Columbia

BC Cancer - Vancouver /ID# 269394, Vancouver, British Columbia

Juravinski Cancer Centre - Hamilton Health Sciences /ID# 269396, Hamilton, Ontario

Kingston General Hospital /ID# 269397, Kingston, Ontario

The Ottawa Hospital - General Campus /ID# 269391, Ottawa, Ontario

Princess Margaret Cancer Centre /ID# 269390, Toronto, Ontario

Universite de Montreal - Hopital Maisonneuve-Rosemont /ID# 269395, Montreal, Quebec

CHUM - Centre hospitalier de l'Universite de Montréal /ID# 269387, Montreal, Quebec

McGill University Health Centre /ID# 269389, Montreal, Quebec

CIUSSS Estrie - Sherbrooke University Hospital Center /ID# 269393, Sherbrooke, Quebec

The first affiliated hospital of bengbu medical college, Bengbu, Anhui

Capital Medical University (Cmu), Beijing, Beijing

Beijing Cancer Hospital, Beijing, Beijing

Fujian Province Cancer Hospital, Fuzhou, Fujian

The First Affiliated Hospital, Sun-Yat Sen University, Guangzhou, Guangdong

Sun Yat-Sen University (Sysu) - Sun Yat-Sen Memorial Hospital, Guangzhou, Guangdong

Affiliated Cancer Hospital of Guangxi Medical University, Nanning, Guangxi

Harbin Medical University Cancer Hospital, Harbin, Heilongjiang

Henan Cancer Hospital, Zhengzhou, Henan

The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan

Hubei Cancer Hospital, Wuhan, Hubei

Hunan Province Cancer Hospital, Changsha, Hunan

The First Bethune Hospital Of Jilin University, Changchun, Jilin

Liaoning Cancer Hospital & Institute, Shenyang, Liaoning

The First Affiliated Hospital of Xi'an Jiaotong University, Xian, Shaanxi

Qilu Hospital Of Shandong University, Jinan, Shandong

Shandong Cancer Hospital, Jinan, Shandong

LinYi Cancer Hospital, Linyi, Shandong

Fudan University Cancer Hospital, Shanghai, Shanghai

Shanxi Cancer Hospital, Taiyuan, Shanxi

West China Second University Hospital, Sichuan University, Chengdu, Sichuan

Tianjin Cancer Hospital, Tianjin, Tianjin

Cancer Hospital Affliated to Xinjiang Medical University, Urumqi, Xinjiang

Yunnan Province Cancer Hospital, Kunming, Yunnan

The Affiliated Women's Hospital Of Zhejiang University, Hangzhou, Zhejiang

Zhejiang Cancer Hospital, Hangzhou, Zhejiang

Fakultní Nemocnice Brno - Jihlavská /ID# 269401, Brno, Brno-mesto

General University Hospital in Prague, Charles University /ID# 269402, Prague, Ceske Budejovice

Nemocnice Novy Jicin /ID# 269400, Nový Jičín, Novy Jicin

Fakultní nemocnice Ostrava /ID# 269403, Ostrava, Ostrava-mesto

Hôpital La Timone /ID# 269421, Marseille, Bouches-du-Rhone

Chu Dijon /Id# 269417, Dijon, Bourgogne-Franche-Comte

CHU Brest /ID# 269422, Brest, Finistere

Centre Leon Berard /ID# 269418, Lyon CEDEX 08, Rhone

Institut Curie /ID# 269420, Paris, Not set

Institut de cancérologie Strasbourg Europe (ICANS) /ID# 269419, Strasbourg, Not set

Klinikum Esslingen /ID# 269435, Esslingen am Neckar, Baden-Wuerttemberg

Universitaetsklinikum Erlangen /ID# 269439, Erlangen, Bayern

Universitaetsklinikum Bonn /ID# 269434, Bonn, Nordrhein-Westfalen

Klinikum Dortmund Klinikzentrum Mitte /ID# 269441, Dortmund, Nordrhein-Westfalen

Universitaetsklinikum Carl Gustav Carus Dresden /ID# 269433, Dresden, Sachsen

Universitätsklinikum Gießen /ID# 269432, Giessen, Not set

Krankenhaus Jerusalem /ID# 269430, Hamburg, Not set

St. Luke's Hospital S.A. /ID# 269445, Panorama, Thessaloniki

General Hospital of Athens Alexandra /ID# 269444, Athens, Not set

Hygeia Hospital /ID# 270132, Athens, Not set

IASO Hospital /ID# 269443, Marousi, Not set

St James Hospital /ID# 269446, Dublin 8, Dublin

Bon Secours Cork Hospital /ID# 269449, Cork, Not set

Cork University Hospital /ID# 269451, Cork, Not set

Beaumont Hospital /ID# 269452, Dublin, Not set

University Hospital Galway /ID# 269447, Galway, Not set

Sligo General Hospital /ID# 269448, Sligo, Not set

Waterford Regional Hospital /ID# 269450, Waterford, Not set

The Lady Davis Carmel Medical Center /ID# 269453, Haifa, H_efa

Edith Wolfson Medical Center /ID# 269461, Holon, HaMerkaz

Meir Medical Center /ID# 269454, Kfar Saba, HaMerkaz

Rabin Medical Center /ID# 269456, Petah Tikva, HaMerkaz

Kaplan Medical Center /ID# 269457, Rekhovot, HaMerkaz

The Chaim Sheba Medical Center /ID# 269094, Ramat Gan, Tel-Aviv

Tel Aviv Sourasky Medical Center /ID# 269455, Tel Aviv, Tel-Aviv

Shaare Zedek Medical Center /ID# 269459, Jerusalem, Not set

Hadassah Medical Center-Hebrew University /ID# 269458, Jerusalem, Not set

ZIV Medical Center /ID# 269460, Safed, Not set

Azienda Ospedaliero Universitaria Careggi /ID# 269465, Florence, Firenze

Ente Ospedaliero Ospedali Galliera /ID# 269472, Genoa, Genova

Ospedale San Martino /ID# 269469, Genoa, Genova

IRCCS Istituto Clinico Humanitas /ID# 269473, Rozzano, Lombardia

IRCCS Ospedale San Raffaele /ID# 269475, Milan, Milano

Istituto Nazionale Dei Tumori /ID# 269477, Milan, Milano

Istituto Nazionale Tumori Irccs Fondazione G. Pascale /ID# 269097, Naples, Napoli

Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST - IRCCS /ID# 269474, Meldola, Reggio Emilia

Azienda Ospedaliero-Universitaria Policlinico Umberto I /ID# 269470, Rome, Roma

Fondazione Policlinico Universitario Agostino Gemelli IRCCS-Università Cattolica /ID# 269096, Rome, Roma

Ospedale di Mirano - Azienda ULSS 3 /ID# 269462, Mirano, Venezia

IRCCS AOU di Bologna Policlinico Sant Orsola Malpighi /ID# 269476, Bologna, Not set

Ospedale Cannizzaro /ID# 269478, Catania, Not set

Alessandro Manzoni Hospital /ID# 269467, Lecco, Not set

Azienda USL Toscana Nord Ovest - Ospedale San Luca /ID# 269095, Lucca, Not set

Azienda Ospedaliero Universitaria Di Parma /ID# 269466, Parma, Not set

Fondazione IRCCS Policlinico San Matteo /ID# 269463, Pavia, Not set

AUSL Piacenza-Ospedale Guglielmo da Saliceto /ID# 269468, Piacenza, Not set

New Hospital of Prato - S. Stefano /ID# 269464, Prato, Not set

AUSL di Reggio Emilia - Arcispedale Santa Maria Nuova /ID# 269471, Reggio Emilia, Not set

Aichi Cancer Center /ID# 274332, Nagoya-shi, Aichi

Chiba University Hospital /ID# 274371, Chiba-shi, Chiba

National Hospital Organization Shikoku Cancer Center /ID# 276078, Matsuyama, Ehime

Kurume University Hospital /ID# 274337, Kurume-shi, Fukuoka

Hokkaido University Hospital /ID# 274331, Sapporo-shi, Hokkaido

Sapporo Medical University Hospital /ID# 274330, Sapporo, Hokkaido

Hyogo Cancer Center /ID# 274323, Akashi-shi, Hyogo

Iwate Medical University Hospital - Yahabacho /ID# 274635, Yahaba, Iwate

Tokai University Hospital /ID# 274336, Isehara, Kanagawa

Tohoku University Hospital /ID# 274327, Sendai-shi, Miyagi

Niigata University Medical & Dental Hospital /ID# 274329, Niigata-shi, Niigata

Okayama University Hospital /ID# 274324, Okayama-shi, Okayama

Saitama Medical University International Medical Center /ID# 274953, Hidaka, Saitama

Shizuoka Cancer Center /ID# 274325, Sunto-gun, Shizuoka

National Cancer Center Hospital /ID# 274321, Chuo-Ku, Tokyo

The Cancer Institute Hospital Of JFCR /ID# 274326, Koto-ku, Tokyo

The Jikei University Hospital /ID# 276160, Minato-ku, Tokyo

Keio University Hospital /ID# 276159, Shinjuku-ku, Tokyo

National Cancer Center /ID# 269481, Goyang-si, Gyeonggido

Seoul National University Bundang Hospital /ID# 269482, Seongnam-si, Gyeonggido

CHA Bundang Medical Center /ID# 269489, Seongnam, Gyeonggido

Keimyung University Dongsan Hospital /ID# 269488, Daegu, Gyeongsangbugdo

Korea University Anam Hospital /ID# 269486, Seoul, Seoul Teugbyeolsi

Seoul National University Hospital /ID# 269479, Seoul, Seoul Teugbyeolsi

Yonsei University Health System Severance Hospital /ID# 269483, Seoul, Seoul Teugbyeolsi

Asan Medical Center /ID# 269480, Seoul, Seoul Teugbyeolsi

Gangnam Severance Hospital /ID# 269484, Seoul, Seoul Teugbyeolsi

Samsung Medical Center /ID# 269487, Seoul, Seoul Teugbyeolsi

The Catholic University of Korea, Seoul St. Marys Hospital /ID# 269485, Seoul, Seoul Teugbyeolsi

Korea University Guro Hospital /ID# 269490, Seoul, Seoul Teugbyeolsi

The Medical City /ID# 269493, Pasig, National Capital Region

East Avenue Medical Center /ID# 269099, Quezon City, National Capital Region

Cardinal Santos Medical Center /ID# 269100, San Juan City, National Capital Region

Mazowiecki Szpital Wojewodzki im. Sw. Jana Pawla II w Siedlcach Sp. z o.o. /ID# 269500, Siedlce, Mazowieckie

Szpitale Pomorskie Sp. z o.o. /ID# 269495, Gdynia, Pomorskie

Complejo Hospitalario Universitario A Coruña /ID# 269414, A Coruña, A Coruna

Institut Català d'Oncologia (ICO) - L'Hospitalet /ID# 269409, L'Hospitalet de Llobregat, Barcelona

Clinica Universidad de Navarra - Pamplona /ID# 269410, Pamplona, Navarra

Hospital Universitari Vall d'Hebron /ID# 269406, Barcelona, Not set

Hospital Clinic de Barcelona /ID# 269408, Barcelona, Not set

Hospital Universitari De Girona Doctor Josep Trueta /ID# 269411, Girona, Not set

CLINICA UNIVERSIDAD DE NAVARRA-Madrid /ID# 269405, Madrid, Not set

Hospital Universitario La Paz /ID# 269407, Madrid, Not set

Hospital Clínico Universitario de Valencia /ID# 269412, Valencia, Not set

Hacettepe University Faculty of Medicine /ID# 269521, Ankara, Not set

Cheltenham General Hospital /ID# 269427, Cheltenham, Gloucestershire

Guy's Hospital /ID# 269426, London, Greater London

The Royal Marsden - Chelsea /ID# 269102, London, Greater London

Mount Vernon Hospital /ID# 269423, Northwood, Greater London

University Hospital Southampton /ID# 269425, Southampton, Hampshire

The Royal Marsden - Sutton /ID# 269103, Sutton, Surrey

The Christie /ID# 269428, Manchester, Not set

Singleton Hospital /ID# 269424, Swansea, Not set

Conditions: Ovarian Cancer, Peritoneal Cancer, Fallopian Tube Cancer

Learn More ›

Open-label Study to Assess Reduction of Background Asthma Medication While Sustaining Asthma Control and Clinical Remission With Tezepelumab in Patients 12-80yrs With Severe Asthma.

NCT06473779

Recruiting

The objective of this study is to assess the potential for tezepelumab-treated patients (subcutaneous administration) to reduce maintenance therapy without loss of asthma control in adolescent and adults with severe asthma.. Study details include: 1. The study duration will be up to 72 weeks. 2. The treatment duration will be up to 68 weeks. 3. The visit frequency will be once every 4 weeks (Q4W).

Gender:

ALL

Ages:

Between 12 years and 80 years

Trial Updated:

07/21/2025

Locations: Research Site, Palmdale, California +83 locations

Research Site, Palmdale, California

Research Site, Colorado Springs, Colorado

Research Site, Miami, Florida

Research Site, Hyattsville, Maryland

Research Site, Boston, Massachusetts

Research Site, Saint Louis, Missouri

Research Site, New Brunswick, New Jersey

Research Site, Oklahoma City, Oklahoma

Research Site, McAllen, Texas

Research Site, Berazategui, Not set

Research Site, Caba, Not set

Research Site, Concepción del Uruguay, Not set

Research Site, Mendoza, Not set

Research Site, Quilmes, Not set

Research Site, Rosario, Not set

Research Site, San Miguel de Tucuman, Not set

Research Site, Santa Fe, Not set

Research Site, Anderlecht, Not set

Research Site, Edegem, Not set

Research Site, Erpent, Not set

Research Site, Gent, Not set

Research Site, Liège, Not set

Research Site, Haskovo, Not set

Research Site, Kozloduy, Not set

Research Site, Pleven, Not set

Research Site, Razgrad, Not set

Research Site, Ruse, Not set

Research Site, Sofia, Not set

Research Site, Stara Zagora, Not set

Research Site, Velika Tarnovo, Not set

Research Site, Edmonton, Alberta

Research Site, Vancouver, British Columbia

Research Site, Ajax, Ontario

Research Site, Windsor, Ontario

Research Site, Sherbrooke, Quebec

Research Site, Regina, Saskatchewan

Research Site, Quebec, Not set

Research Site, Aalborg, Not set

Research Site, Hvidovre, Not set

Research Site, Svendborg, Not set

Research Site, Vejle, Not set

Research Site, Bordeaux, Not set

Research Site, Créteil, Not set

Research Site, La Tronche, Not set

Research Site, Lyon, Not set

Research Site, Marseille, Not set

Research Site, Montpellier, Not set

Research Site, Strasbourg, Not set

Research Site, Augsburg, Not set

Research Site, Bonn, Not set

Research Site, Cottbus, Not set

Research Site, Hamburg, Not set

Research Site, Hannover, Not set

Research Site, Mainz, Not set

Research Site, München, Not set

Research Site, Cagliari, Not set

Research Site, Catania, Not set

Research Site, Firenze, Not set

Research Site, Orbassano, Not set

Research Site, Roma, Not set

Research Site, Salerno, Not set

Research Site, Verona, Not set

Research Site, Chihuahua, Not set

Research Site, Cuauhtémoc, Not set

Research Site, Guadalajara, Not set

Research Site, Monterrey, Not set

Research Site, Veracruz, Not set

Research Site, Badalona(Barcelona), Not set

Research Site, Barcelona, Not set

Research Site, Lugo, Not set

Research Site, Madrid, Not set

Research Site, Pamplona, Not set

Research Site, Rosario, Not set

Research Site, Belfast, Not set

Research Site, Liverpool, Not set

Research Site, London, Not set

Research Site, Southampton, Not set

Conditions: Severe Asthma

Learn More ›

A Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)

NCT05384626

Recruiting

Phase 1/2, dose escalation and expansion study designed to evaluate the safety and tolerability of neladalkib (NVL-655), determine the recommended phase 2 dose (RP2D), and evaluate the antitumor activity in patients with advanced ALK- positive (ALK+) NSCLC and other solid tumors. Phase 1 will evaluate the overall safety and tolerability of neladalkib and will determine the RP2D and, if applicable, the maximum tolerated dose (MTD) of neladalkib in patients with advanced ALK+ solid tumors. Phase... Read More

Gender:

ALL

Ages:

12 years and above

Trial Updated:

07/21/2025

Locations: University of California Irvine Medical Center, Orange, California +73 locations

University of California Irvine Medical Center, Orange, California

University of California, Davis Comprehensive Cancer Center, Sacramento, California

Stanford Cancer Institute, Stanford, California

University of Colorado Cancer Center, Aurora, Colorado

Georgetown University Medical Center, Washington, District of Columbia

University of Miami; Sylvester Cancer Center, Miami, Florida

Winship Cancer Institute, Emory University, Atlanta, Georgia

University of Chicago Medical Center, Chicago, Illinois

John Hopkins University, Baltimore, Maryland

Massachusetts General Hospital, Boston, Massachusetts

Dana Farber Cancer Institute, Boston, Massachusetts

Henry Ford Cancer Institute, Detroit, Michigan

Washington University School of Medicine Siteman Cancer Center, Saint Louis, Missouri

Laura & Isaac Perlmutter Cancer Center at NYU Langone Health, New York, New York

Memorial Sloan Kettering Cancer Center, New York, New York

Duke University Medical Center, Durham, North Carolina

OSU Brain & Spine Hospital, Columbus, Ohio

University of Pennsylvania, Abramson Cancer Center, Philadelphia, Pennsylvania

Sarah Cannon, Nashville, Tennessee

MD Anderson Cancer Center, Houston, Texas

Fred Hutchinson Cancer Center, Seattle, Washington

Royal North Shore Hospital, Sydney, New South Wales

Princess Alexandra Hospital, Woolloongabba, Queensland

Peter MacCallum Cancer Centre, Melbourne, Victoria

Universitair Ziekenhuis Antwerpen (UZA), Antwerp, Not set

Universitaire Ziekenhuizen Leuven Campus Gastthuisberg, Leuven, Not set

Cross Cancer Institute, Edmonton, Alberta

BC Cancer Center, Vancouver, British Columbia

The Ottawa Hospital Cancer Center, Ottawa, Ontario

Princess Margaret Cancer Centre, Toronto, Ontario

Centre Leon Berard, Lyon, Not set

Chu De Nantes, Nantes, Not set

Institut Claudius Regaud, Toulouse Cedex, Not set

Institute Gustave Roussy, Villejuif, Not set

Universitatsklinikum Koln - University Hospital Cologne, Cologne, Not set

Universitätsklinikum Frankfurt, Frankfurt, Not set

LungenClinic Grosshansdorf GmbH, Grosshansdorf, Not set

Universkitatsklinikum Heidelberg - University Hospital Heidelberg, Heidelberg, Not set

Azienda Ospedaliera Universitaria Ospedali Riuniti Umberto, Ancona, Not set

IRCCS Istituto Tumori "G. Paolo II", Bari, Not set

Instituto Europeo di Oncologia, Milano, Not set

Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Not set

Instituto Oncologico Veneto, Padova, Not set

Ospedale Santa Maria delle Croci, Ravenna, Not set

Regina Elena Institute for Cancer Research, Rome, Not set

Kanagawa Cancer Center, Kanagawa, Not set

Okayama University Hospital, Okayama, Not set

Kindai University Hospital, Osaka, Not set

Shizuoka Cancer Center, Shizuoka, Not set

National Cancer Center Hospital, Tokyo, Not set

Center Institute Hospital of JFCR, Tokyo, Not set

Wakayama Medical University Hospital, Wakayama, Not set

National Cancer Center, Goyang-si, Gyeonggi-do

Seoul National University Hospital, Seoul, Not set

Severance Hospital Yonsei University Health System, Seoul, Not set

Samsung Medical Center, Seoul, Not set

The Netherlands Cancer Institute, Amsterdam, Not set

University Medical Center Groningen (UMCG), Groningen, Not set

National University Hospital, Singapore, Not set

National Cancer Centre Singapore, Singapore, Not set

Complejo Hospitalario Universitario de A Coruna, A Coruña, Not set

UOMI Cancer Center, Barcelona, Not set

Vall d'Hebron, Barcelona, Not set

Hospital General Universitario Gregorio Maranon, Madrid, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

Istituto Oncologico Svizzera Italiana, Bellinzona, Not set

Luzerner Kantonsspital, Luzern, Not set

Chung-Shan Medical University Hospital, Taichung City, Not set

National Cheng Kung University Hospital, Tainan, Not set

National Taiwan University Hospital, Taipei, Not set

Royal Marsden Hospital, Sutton, Surrey

Edinburgh Cancer Centre, Edinburgh, Not set

The Royal Marsden - Chelsea, London, Not set

The Christie NHS Foundation Trust, Manchester, Not set

Conditions: Locally Advanced Solid Tumor, Metastatic Solid Tumor

Learn More ›

A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma

NCT06007690

Recruiting

The primary objective is to determine the safety and efficacy of belzupacap sarotalocan (bel-sar) compared to sham control in patients with primary indeterminate lesions (IL) or small choroidal melanoma (CM).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/20/2025

Locations: Retina Consultants of Alabama, Birmingham, Alabama +57 locations

Retina Consultants of Alabama, Birmingham, Alabama

UCSD Shiley Eye Institute, Jacobs Retina Center, La Jolla, California

Doris Stein Eye Research Center, Los Angeles, California

Stanford University School of Medicine, Palo Alto, California

Retinal Consultants Medical Group, Inc., Sacramento, California

Bascom Palmer Eye Institute, Miami, Florida

Retina Associates of Florida, PA, Tampa, Florida

Emory Eye Center, Atlanta, Georgia

University of Illinois at Chicago, Chicago, Illinois

Tufts Medical Center New England Eye Center, Boston, Massachusetts

Massachusetts Eye and Ear, Boston, Massachusetts

W.K. Kellogg Eye Center - University of Michigan, Ann Arbor, Michigan

Associated Retinal Consultants (ARC) P.C., Royal Oak, Michigan

Mayo Clinic, Rochester, Minnesota

Washington University, Saint Louis, Missouri

Nebraska Medicine's Truhlsen Eye Institute, Omaha, Nebraska

New Jersey Retina Group, Wayne, New Jersey

Columbia University Irving Medical Center, New York, New York

Duke Eye Center, Durham, North Carolina

Cole Eye Institute, Cleveland, Ohio

Dean McGee Eye Institute, Oklahoma City, Oklahoma

Shields & Shields PC-Wills Eye Institute, Philadelphia, Pennsylvania

Retina Consultants of Carolina, Greenville, South Carolina

Southeastern Retina Associates, Chattanooga, Tennessee

Tennessee Retina, PC, Nashville, Tennessee

Austin Retina Associates, Austin, Texas

Texas Retina Associates, Dallas, Texas

UT, Southwestern Medical Center, Dallas, Texas

Retina Associates of South Texas, P.A., San Antonio, Texas

Retina Center of Texas, Southlake, Texas

Retina Consultants of Texas, The Woodlands, Texas

Retina Associates of Utah, Salt Lake City, Utah

Vitreoretinal Associates of Washington, Bellevue, Washington

University of Washington Medical Center, Seattle, Washington

University of Wisconsin Madison, Madison, Wisconsin

Terrace Eye Centre, Brisbane, Queensland

Eye Research Australia, East Melbourne, Victoria

UZ Leuven, Leuven, Not set

Serac Eye and Skin Care Centre, Calgary, Alberta

Princess Margaret Eye Tumour Clinic, Toronto, Ontario

Centre Hospitalier de l'Universite Laval, Québec City, Quebec

Fakultni Thomayerova nemocnice, Praha 4, Krč

Fakultni nemocnice Plzen, Plzen, Plzenský Kraj

Ustredni vojenska nemocnice Vojenska fakultni nemocnice Praha, Praha 6, Not set

Centre Hospitalier Universitaire de Nice, Nice, Cedex 1

Charité - Universitätsmedizin Berlin KöR, Berlin, Not set

Universitätsklinikum Schleswig-Holstein Klinik für Augenheilkunde, Lübeck, Not set

Universitätsklinikum Tübingen, Tübingen, Not set

The Chaim Sheba Medical Center, Tel-Hashomer, HaMerkaz

Hadassah Medical Center, Ein-Karem, Jerusalem, Yerushalayim

Leids Universitair Medisch Centrum (LUMC), Leiden, Not set

Erasmus MC, Rotterdam, Not set

Auckland Eye Ltd, Auckland, Not set

Hospital Universitario de Bellvitge, Barcelona, Not set

Hospital Provincial de Conxo, Santiago de Compostela, Not set

Royal Liverpool University Hospital Nhs Foundation Trust Broadgreen Hospital, Liverpool, England

Moorfields Eye Hospital NHS Foundation Trust, London, Not set

Nhs Foundation Trust - Royal Hallamshire Hospital, Sheffield, Not set

Conditions: Choroidal Melanoma, Indeterminate Lesions, Uveal Melanoma, Ocular Melanoma

Learn More ›

A Study Evaluating the Efficacy and Safety of Pirtobrutinib in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

NCT06588478

Recruiting

The main purpose of Part 1 of this study is to assess the efficacy and safety of 3 dose levels of Pirtobrutinib in participants with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL), who have received 1-3 lines of treatment including a covalent Bruton tyrosine kinase (BTK) inhibitor. The purpose of Part 2 of this study is to evaluate pirtobrutinib monotherapy in participants with treatment-naïve CLL/SLL with 17p deletions. Participation in Part 1 is expected to last approxi... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/18/2025

Locations: Ironwood Cancer & Research Centers, Chandler, Arizona +135 locations

Ironwood Cancer & Research Centers, Chandler, Arizona

City of Hope National Medical Center, Duarte, California

City of Hope National Medical Center, Irvine, California

Palo Alto Medical Foundation Research Institute (PAMFRI), Palo Alto, California

Stanford Cancer Center, Palo Alto, California

Rocky Mountain Cancer Center, Aurora, Colorado

University of Miami Hospital and Clinics, Sylvester Cancer Center, Miami, Florida

City of Hope National Medical Center, Atlanta Cancer Center, Newnan, Georgia

Mission Cancer + Blood, Waukee, Iowa

Saint Elizabeth Medical Center Edgewood, Edgewood, Kentucky

American Oncology Partners of Maryland, PA, Bethesda, Maryland

Boston Medical Center, Boston, Massachusetts

Gulfport Memorial Hospital, Gulfport, Mississippi

Comprehensive Cancer Centers of Nevada, Henderson, Nevada

Clinical Research Alliance, Westbury, New York

East Carolina University, Greenville, North Carolina

Williamette Valley Cancer Institute & Research Center, Eugene, Oregon

Cancer Care Associates Of York, York, Pennsylvania

The West Clinic, PLLC dba West Cancer Center, Germantown, Tennessee

USO-Texas Oncology-Central/South Texas, Austin, Texas

Sarah Cannon Research Institute/SCRI, The Woodlands, Texas

USO-Virginia Oncology Associates, Hampton, Virginia

USO-Northwest Cancer Specialists, PC, Vancouver, Washington

Bankstown-Lidcombe Hospital, Bankstown, New South Wales

Coffs Harbour Health Campus, Coffs Harbour, New South Wales

Calvary Mater Newcastle, Waratah, New South Wales

Princess Alexandra Hospital, Woolloongabba, Queensland

Flinders Medical Centre, Adelaide, South Australia

ICON Cancer Centre - Kurralta Park, Kurralta Park, South Australia

Royal Hobart Hospital, Hobart, Tasmania

Box Hill Hospital, Box Hill, Victoria

Latrobe Regional Health, Traralgon, Victoria

The Perth Blood Institute - West Perth, West Perth, Western Australia

Clinique Saint Pierre, Ottignies, Brabant Wallon

Institut Jules Bordet, Anderlecht, Bruxelles-Capitale, Région De

Groupe Jolimont, La Louvière, Hainaut

CHR Verviers - La Tourelle, Verviers, Liège

UZ Gent, Gent, Oost-Vlaanderen

AZ Nikolaas, Sint-Niklaas, Oost-Vlaanderen

UZ Leuven, Leuven, Vlaams-Brabant

AZ Sint-Jan Brugge-Oostende AV, Brugge, West-Vlaanderen

AZ Delta vzw, Roeselare, West-Vlaanderen

Royal Victoria Regional Health Centre, Barrie, Ontario

CIUSSS- saguenay-Lac-Saint-Jean, Chicoutimi, Quebec

Saskatoon Cancer Centre, Saskatoon, Saskatchewan

Fakultní nemocnice Brno Bohunice, Brno, Brno-město

Fakultni nemocnice Hradec Kralove, Hradec Kralove, Hradec Králové

Fakultni nemocnice Kralovske Vinohrady, PRague, Praha 10

Vseobecna fakultni nemocnice v Praze, Praha 2, Not set

Aarhus Universitetshospital, Skejby, Aarhus, Midtjylland

Odense Universitetshospital, Odense, Syddanmark

Centre Antoine-Lacassagne, Nice, Alpes-Maritimes

Groupe Hospitalier de la Région de Mulhouse et Sud Alsace - Hôpital Emile Muller, Mulhouse, Alsace

Centre Hospitalier Universitaire de Caen - Hôpital Côte de Nacre, Caen, Calvados

Centre Hospitalier Régional Universitaire de Tours - Hôpital Bretonneau, Tours, Indre-et-Loire

Centre Hospitalier du Mans, Le Mans, Sarthe

Centre Hospitalier d'Argenteuil Victor Dupouy, Argenteuil, Val-d'Oise

Klinikum Aschaffenburg-Alzenau, Aschaffenburg, Bayern

Centrum für Hämatologie und Onkologie Bethanien, Frankfurt, Hessen

OSP Göttingen, Goettingen, Niedersachsen

Onkologisches Ambulanzzentrum Hannover, Hannover, Niedersachsen

MV-Zentrum für Onkologie und Hämatologie, Cologne, Nordrhein-Westfalen

InVO Institut für Versorgungsforschung in der Onkologie, Koblenz, Rheinland-Pfalz

Evangelismos General Hospital of Athens, Athens, Attikí

Attikon General University Hospital, Chaidari, Attikí

General Hospital of Athens "Laiko", Αthens, Attikí

G. Papanikolaou General Hospital, Thessaloniki, Thessaloníki

Pécsi Tudományegyetem Klinikai Központ, Pécs, Baranya

Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ, Szeged, Csongrád

Semmelweis Egyetem, Budapest, Not set

Dél-Pesti Centrumkórház, Budapest, Not set

Azienda Ospedaliero Universitaria S.Anna, Cona, Emilia-Romagna

Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore, Roma, Lazio

ASST Grande Ospedale Metropolitano Niguarda, Milan, Lombardia

A.O.U.C. Policlinico di Bari, Bari, Puglia

Az. Osp. Ospedali Riuniti VILLA SOFIA-CERVELLO, Palermo, Sicilia

Azienda Ospedaliera Universitaria Careggi, Firenze, Toscana

AO Santa Maria della Misericordia, Perugia, Umbria

Azienda Ospedale - Università Padova, Padova, Veneto

Azienda Ospedaliero Universitaria Maggiore della Carità, Novara, Not set

AOU Policlinico Umberto I, Roma, Not set

Chonnam National University Hwasun Hospital, Hwasun-gun, Jeonranamdo

Pusan National University Hospital, Busan, Pusan-Kwangyǒkshi

Seoul National University Hospital, Seoul, Seoul-teukbyeolsi [Seoul]

Samsung Medical Center, Seoul, Seoul-teukbyeolsi [Seoul]

The Catholic Univ. of Korea Seoul St. Mary's Hospital, Seoul, Seoul-teukbyeolsi [Seoul]

The Catholic University of Korea, Yeouido St. Mary's Hospital, Seoul, Seoul-teukbyeolsi [Seoul]

Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego we Wrocławiu, Wrocław, Dolnośląskie

IN VIVO, Bydgoszcz, Kujawsko-pomorskie

Pratia MCM Krakow, Kraków, Małopolskie

AIDPORT Sp. z o.o., Skórzewo, Wielkopolskie

Pratia Onkologia Katowice, Katowice, Śląskie

Fundeni Clinical Institute, Bucuresti, București

Ovidius Clinical Hospital OCH, Ovidiu, Constanța

Spitalul Clinic Municipal Filantropia Craiova, Craiova, Dolj

Spitalul Clinic Colțea, București, Not set

Institutul Oncologic Cluj, Cluj, Not set

Institutul Regional de Oncologie, Iași, Not set

Fakultna nemocnica s poliklinikou F.D.Roosevelta Banska Bystrica, Banska Bystrica, Banskobystrický Kraj

Narodny onkologicky ustav, Bratislava, Bratislavský Kraj

Univerzitna Nemocnica L. Pasteura Kosice, Kosice, Košický Kraj

Univerzitna nemocnica Martin, Martin, Žilinský Kraj

Hospital Universitario Virgen Macarena, Sevilla, Andalucía

Hospital Universitario Central de Asturias, Oviedo, Asturias

Institut Català d'Oncologia (ICO) - Badalona, Badalona, Barcelona [Barcelona]

Hospital Universitari Vall d'Hebron, Barcelona, Barcelona [Barcelona]

Institut Català d'Oncologia - L'Hospitalet, L'Hospitalet Del Llobregat, Barcelona [Barcelona]

Hospital Universitario Marqués de Valdecilla, Santander, Cantabria

Hospital Clínic de Barcelona, Barcelona, Catalunya [Cataluña]

Clinica Universidad de Navarra, Madrid, Madrid, Comunidad De

Hospital Universitario Infanta Leonor, Madrid, Madrid, Comunidad De

MD Anderson Cancer Center, Madrid, Madrid, Comunidad De

Hospital Universitario Ramón y Cajal, Madrid, Madrid, Comunidad De

Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda, Madrid, Comunidad De

Hospital Costa del Sol, Marbella, Málaga

Hospital Universitario Quironsalud Madrid, Madrid, Not set

Hospital Universitario de Salamanca - Complejo Asistencial Universitario de Salamanca, Salamanca, Not set

Hospital Universitario Virgen Del Rocio, Sevilla, Not set

Kocaeli Üniversitesi, Izmit, Kocaeli

Sakarya University School of Medicine, Adapazarı, Sakarya

Dr. Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastırma Hastanesi, Ankara, Not set

Ankara University Health Practice and Research Hospitals, Ankara, Not set

Memorial Antalya Hospital, Antalya, Not set

Yeditepe Üniversitesi Koşuyolu Hastanesi, Istanbul, Not set

Ege Universitesi Hastanesi, Izmir, Not set

VM Medical Park Mersin Hastanesi, Mersin, Not set

Ondokuz Mayıs Universitesi, Samsun, Not set

Maidstone Hospital, Maidstone, Kent

Lincoln County Hospital, Lincoln, Lincolnshire

Northwick Park Hospital, Harrow, London, City Of

Hammersmith Hospital, London, London, City Of

Heartlands Hospital, Birmingham, Not set

The Beatson West of Scotland Cancer Centre, Glasgow, Not set

St James's University Hospital, Leeds, Not set

Clatterbridge Cancer Centre - Liverpool, Liverpool, Not set

Singleton Hospital, Swansea, Not set

Conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma

Learn More ›

A Trial to Learn if Odronextamab is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Different Types of Chemotherapy for Participants With Follicular Lymphoma

NCT06091254

Recruiting

This study is researching an experimental drug called odronextamab, referred to as study drug. The study is focused on participants with previously untreated follicular lymphoma (a type of non-Hodgkin lymphoma or NHL). This study will be made up of two parts: Part 1 (non-randomized) and Part 2 (randomized - controlled). The aim of Part 1 of the study is to see how safe and tolerable the study drug is when given alone. The aim of Part 2 of the study is to see how the study drug works compared... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/18/2025

Locations: University of Arizona Cancer Center, Tucson, Arizona +186 locations

University of Arizona Cancer Center, Tucson, Arizona

David Geffen School of Medicine at UCLA, Los Angeles, California

UC Irvine Health, Orange, California

Investigative Clinical Research of Indiana, Noblesville, Indiana

Beth Israel Deaconess Medical Center, Boston, Massachusetts

Karmanos Cancer Institute, Detroit, Michigan

Hattiesburg Clinic, Hattiesburg, Mississippi

Icahn School of Medicine at Mt Sinai, New York, New York

Stony Brook University Hospital, Stony Brook, New York

Clinical Research Alliance Inc, Westbury, New York

University of North Carolina, Chapel Hill, North Carolina

Levine Cancer Institute, Charlotte, North Carolina

University Hospitals Cleveland Medical Center, Cleveland, Ohio

Vanderbilt University Medical Center, Nashville, Tennessee

Center for Oncology and Blood Disorders, Houston, Texas

HOPE Cancer Center of East Texas, Tyler, Texas

Huntsman Cancer Institute - Oncology Division, Salt Lake City, Utah

University of Virginia, Charlottesville, Virginia

Virginia Commonwealth University, Richmond, Virginia

Prohealth Care Inc, Waukesha, Wisconsin

Ingham Institute, Liverpool, New South Wales

Icon Cancer Centre - Wesley, Auchenflower, Queensland

Flinders Medical Centre, Bedford Park, South Australia

Monash Health, Clayton, Victoria

Epworth Freemasons, East Melbourne, Victoria

St Vincent's Hospital - Melbourne, Fitzroy, Victoria

Alfred Hospital and Monash University, Melbourne, Victoria

Ordensklinikum Linz, Linz, Osterreich

Ordensklinikum Linz Gmbh, Elisabethinen, Linz, Not set

Uniklinikum Salzburg (LKH) Universitatsklinik fur Innere Medizin III, Salzburg, Not set

Medical University of Vienna, Vienna, Not set

Hanusch Krankenhaus, Vienna, Not set

AZ St.-Elisabeth Herentals vzw, Herentals, Antwerp

Hopital De Jolimont, Haine-Saint-Paul, Hainaut

Universitair Ziekenhuis (UZ) Gent/ Ghent University Hospital, Gent, Oost-Vlaanderen

Ziekenhuis Netwerk Antwerpen Stuivenberg, Antwerp, Not set

Institut Jules Bordet, Brussels, Not set

Ensino e Terapia de Inovacao Clinica Amo (Etica), Salvador, Bahia

Instituto Mario Pena de Ensino Pesquisa e Inovacao, Belo Horizonte, Minas Gerais

Liga Norte Riograndense Contra o Cancer, Natal, Rio Grande Do Norte

Instituto do Cancer em Hospital Sao Vicente de Paulo, Passo Fundo, Rio Grande Do Sul

Hospital de Clinicas de Porto Alegre, Porto Alegre, Rio Grande Do Sul

Centro de Hematologia e Oncologia, Joinville, Santa Catarina

Animi Unidade de Tratamento Oncologico Ltda, Lages, Santa Catarina

Fundacao Pio XII Hospital de Amor, Barretos, Sao Paulo

Amaral Carvalho Hospital, Jau, Sao Paulo

Hospital das Clinicas da Faculdade de Medicina de Ribeirao Preto da Universidade de Sao Paulo, Ribeirao Preto, Sao Paulo

Instituto DOr de Pesquisa e Ensino Df Star, Brasilia, Not set

Instituto Nacional de Cancer Jose Alencar Gomes da Silva, Rio de Janeiro, Not set

Instituto Americas, Rio de Janeiro, Not set

Hospital Alemao Oswaldo Cruz, Sao Paulo, Not set

AC Camargo Cancer Center, Sao Paulo, Not set

Clinical Hospital of Medicine School at Sao Paulo University, Sao Paulo, Not set

Casa de Saude Santa Marcelina, Sao Paulo, Not set

Tom Baker Cancer Center, Calgary, Alberta

Saint John Regional Hospital, Saint John, New Brunswick

Cisss de la Monteregie-Centre, Greenfield Park, Quebec

CHU de Quebec - Universite Laval, Quebec City, Quebec

Ciusss de Lestrie - Centre Hospitalier Universitaire de Sherbrooke (CHUS), Sherbrooke, Quebec

Fundacion Arturo Lopez Perez, Santiago, Region Metropolitana

Inmunocel, Santiago, Region Metropolitana

Clinica Alemana de Santiago, Santiago, Region Metropolitana

Centro Oncologia de Precision Universidad Mayor, Santiago, Not set

University Hospital Hradec Kralove, Hradec Kralove, Not set

University Hospital Kralovske Vinohrady, Prague, Not set

Vseobecna Fakultni Nemocnice, Praha, Not set

Centre Hospitalier Universitaire (CHU) Rennes, Rennes, Bretagne

Centre Hospitalier Regional Universitaire de Tours, Tours, Centre Val De Loire

Hopital Victor Dupouy Argenteuil, Argenteuil, Ile De France

Gustave Roussy, Villejuif, Ile De France

Nantes University Hospital, Nantes, Pays De La Loire

Hopital de la Conception, Marseille, Provence-Alpes-Cote d'Azur

Centre Hospitalier Universitaire Angers, Angers, Not set

Institut Paoli Calmettes, Marseille, Not set

Hopital Saint Louis, Paris, Not set

Hopital Saint-Antoine, Paris, Not set

Centre Hospitalier Universitaire (CHU) de Poitiers, Poitiers, Not set

Institut de Cancerologie Strasbourg Europe (ICANS), Strasbourg, Not set

University Hospital Wurzburg, Würzburg, Bavaria

Kliniken Ostalb Stauferklinikum Schwab Gmund, Mutlangen, Gmund

Clinic Frankfurt (Oder), Frankfurt, Hesse

Universitatsmedizin der Johannes-Gutenberg Universitat Mainz, Mainz, Rheinland-Pfalz

Hematological Praxis Dresden, Dresden, Sachsen

Charite Universitatsmedizin Berlin Campus Benjamin Franklin, Berlin, Not set

University Hospital Carl Gustav Carus, Dresden, Not set

Stadtisches Krankenhaus Kiel, Kiel, Not set

Samson Assuta Ashdod University Hospital, Ashdod, Not set

Bnai Zion Medical Center, Haifa, Not set

Hadassah Medical Center, Jerusalem, Not set

Galilee Medical Center, Nahariya, Not set

Rabin Medical Center, Petah-Tikva, Not set

Chaim Sheba Medical Center, Ramat-Gan, Not set

Tel Aviv Sourasky Medical Center, Tel Aviv, Not set

Istituto Romagnolo Per Lo Studio Dei Tumori, Meldola, Forli Cesena

Irccs Aou Di Bologna- Policlinico Di Sant'Orsola Malpighi, Bologna, Italia

Pia Fondazione Panico, Tricase, Lecce

IRCCS Ospedale Policlinico San Martino, Genoa, Liguria

Candiolo Cancer Institute, FPO, IRCCS, Candiolo, Torino

UOC Ematologia e Terapia Cellulare - PO Mazzoni AST Ascoli Piceno, Ascoli Piceno, Not set

Azienda Ospedaliera Spedali Civili di Brescia, Brescia, Not set

Istituto Europeo di Oncologia, Milano, Not set

Federico II University, Napoli, Not set

AOU Maggiore della Carita-SCDU Ematologia, Novara, Not set

UO Ematologia Ravenna, Ravenna, Not set

Santa Maria della Misericordia, Udine, Not set

Ospedale dell'Angelo - Varese, Varese, Not set

Center for Hematologic Malignancy, Goyang, Gyeonggi-do

St. Vincents Hospital - The Catholic University of Korea, Suwon-si, Gyeonggi-do

Ajou University Hospital, Suwon-si, Gyeonggi-do

Dong-A University Hospital, Busan, Not set

Pusan National University Hospital, Busan, Not set

Jeonbuk National University Hospital, Jeonju, Not set

Seoul St. Mary's Hospital, Seoul, Not set

Uniwersytecki Szpital Kliniczny, Wroclaw, Dolnoslaskie

Specjalistyczny Szpital im A. Sokolowskiego w Walbrzychu, Walbrzych, Lower Silesian

Pratia MCM Krakow, Krakow, Malopolska

Uniwersyteckie Centrum Kliniczne, Gdansk, Pomorskie

Cm Pratia Poznan, Skorzewo Poznan, Wielkopolska

Aidport, Skorzewo, Wielkopolska

Pratia Onkologia Katowice, Katowice, Not set

Copernicus Memorial Hospital, Lodz, Not set

Centrum Innowacyjnych Terapii Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie, Lublin, Not set

Narodowy Instytut Onkologii im Marii Sklodowskiej Curie Panstwowy Instytut Badawczy Warszawa, Warszawa, Not set

University Hospital of Santiago de Compostela, Santiago de Compostela, A Coruna

Hospital Universitario Virgen De La Victoria Malaga, Malaga, Andalucia

Hospital Universitario Virgen Macarena, Sevilla, Andalucia

Hospital Universitario Central De Asturias, Oviedo, Asturias

Son Espases University Hospital, Palma, Balearic Islands

Cruces University Hospital (Hospital Universitario Cruces), Barakaldo, Bizkaia

Hospital Universitario Marques de Valdecilla, Santander, Cantabria

Complejo Hospitalario Universitario de a Coruna, A Coruna, Galicia

Hospital Universitario Quironsalud Madrid, Pozuelo de Alarcon, Madrid

Hospital Clinico Universitario Virgen De La Arrixaca, El Palmar, Murcia

Hospital Universitario de Navarra, Pamplona, Navarra

University Hospital Vall d'Hebron, Barcelona, Not set

Hospital de la Santa Creu i Sant Pau, Barcelona, Not set

Hospital Virgen De Las Nieves De Granada, Granada, Not set

Gregorio Maranon, Madrid, Not set

Clinica Universidad de Navarra, Madrid, Not set

Fundacion Jimenez Diaz University Hospital, Madrid, Not set

University Hospital & Research Institute, Madrid, Not set

Hospital Universitario HM Sanchinarro, Servicio de Hematologia, Madrid, Not set

Morales Meseguer Hospital, Murcia, Not set

Complexo Hospitalario Universitario de Ourense, Ourense, Not set

Hospital Universitario de Salamanca, Salamanca, Not set

Hospital Universitario Virgen de Valme, Sevilla, Not set

University Hospital Virgen del Rocio, Seville, Not set

Hospital General Universitario de Toledo, Toledo, Not set

Hospital Clinico Universitario Valencia, Valencia, Not set

Hospital Universitari and Politecnic La Fe, Valencia, Not set

Hospital Clinico Lozano Blesa, Zaragoza, Not set

Kantonsspital Baden, Baden, Aargau

Cantonal Hospital St Gallen, St Gallen, Saint Gallen

Kantonsspital Winterthur Medical Oncology, Winterthur, Schweiz

University Hospital Basel, Basel, Not set

Inselspital Bern University Hospital, Bern, Not set

Chang Gung Medical Foundation Chia Yi Branch, Puzi City, Chiayi County

Chang Gung Memorial Hospital Linkou, Taoyuan City, Guishan District

Changhua Christian Hospital, Changhua City, Not set

Chung-Ho Memorial Hospital, Kaohsiung, Not set

Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Not set

Taipei Medical University-Shuang Ho Hospital, New Taipei City, Not set

Taichung General Veterans Hospital, Taichung, Not set

National Cheng Kung University Hospital, Tainan, Not set

Tri-Service General Hospital, Taipei City, Not set

National Taiwan University Hospital, Taipei, Not set

Taipei Veterans General Hospital, Taipei, Not set

Taipei Municipal Wan Fang Hospital, Taipei, Not set

Ankara University Faculty of Medicine, Mamak, Ankara

Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, Yenimahalle, Ankara

Gazi University, Ankara, Central Anatolia

VM Medical Park Mersin Hospital, Mezitli, Mersin

Tekirdag Namik Kemal University Hospital, Tekirdag, Suleymanpasa

Liv Hospital Ankara, Ankara, Not set

VKV American Hopital, Istanbul, Not set

Istanbul University Istanbul Faculty of Medicine, Istanbul, Not set

Ege University, Izmir, Not set

Erci̇yes Uni̇versi̇ty, Kayseri, Not set

Sakarya University Medical Faculty, Sakarya, Not set

Ondokuz Mayis Universitesi Tip Fakultesi Hastanesi, Samsun, Not set

Zonguldak Bulent Ecevit University, Zonguldak, Not set

Royal Cornwall Hospital NHS Trust, Truro, Cornwall

Derriford Hospital and the Royal Eye Infirmary, Plymouth, Devon

University Hospitals Dorset, Bournemouth, Dorset

Beatson West of Scotland Cancer Centre, Glasgow, Lanarkshire

Norfolk and Norwich University Hospital, Norwich, Norfolk

Barking, Havering and Redbridge University Hospitals NHS Trust, Romford, Not set

Conditions: Follicular Lymphoma (FL)

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Study of ECI830 Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer and Other Advanced Solid Tumors

NCT06726148

Recruiting

Phase I: Characterize safety and tolerability of ECI830 as a single agent and in combination with ribociclib and fulvestrant. Identify dose range for optimization/recommended dose for future studies. Phase II: Assess the anti-tumor activity of ECI830 in combination with ribociclib and fulvestrant in patients with hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2-) advanced breast cancer.

Gender:

ALL

Ages:

Between 18 years and 100 years

Trial Updated:

07/18/2025

Locations: Florida Cancer Specialists, Fort Myers, Florida +11 locations

Conditions: Advanced HR+/HER2- Breast Cancer, Advanced CCNE1-amplified Solid Tumors

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