The state of California currently has 74 active clinical trials seeking participants for Arthritis research studies. These trials are conducted in various cities, including Los Angeles, San Francisco, San Diego and Sacramento.
Microfragmented Adipose Tissue Compared to Saline Injection for the Treatment of Knee Osteoarthritis
Recruiting
The goal of this clinical trial is to examine the effect of a single autologous, intra-articular injection of MFat versus saline injection for the treatment of pain and function associated with K/L grade 2/3 knee Osteoarthritis. Participants will receive an injection of MFat or saline.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/17/2024
Locations: CORE Orthopaedic Medical Center, Encinitas, California +2 locations
Conditions: Knee Osteoarthritis, Osteo Arthritis Knee
Innovations in Genicular Outcomes Registry
Recruiting
The registry will capture prospective data on patients receiving pain management for chronic pain due to knee osteoarthritis (OA) or pain optimization for knee arthroplasty due to knee OA. The OA pain therapies may include cryo nerve block, radiofrequency ablation (RFA), intra-articular (IA) corticosteroids, viscosupplementation, opioids, and others (e.g., non-steroidal anti-inflammatory drugs [NSAIDs]).
Gender:
All
Ages:
All
Trial Updated:
05/13/2024
Locations: Orthopedic Education and Research Institute of So Ca (Hoag), Irvine, California +1 locations
Conditions: Knee Osteoarthritis
Zimmer Biomet Shoulder Arthroplasty PMCF
Recruiting
The objectives of this study are to confirm the safety, performance, and clinical benefits of Zimmer Biomet Shoulder Arthroplasty Systems and its instrumentation in primary or revision shoulder arthroplasty. These objectives will be assessed using standard scoring systems, radiographic evidence, and adverse event records. Safety of the system will be assessed by monitoring the frequency an incidence of adverse events.
Gender:
All
Ages:
20 years and above
Trial Updated:
05/09/2024
Locations: Hoag Orthopedic Institute, Irvine, California
Conditions: Shoulder Fractures, Shoulder Arthritis, Shoulder Osteoarthritis, Shoulder Deformity, Shoulder Injuries, Shoulder Pain
Effect of Anti-inflammatory Diet in Rheumatoid Arthritis
Recruiting
In a previous exploratory study, the investigators observed an effect on disease activity outcomes of anti-inflammatory diet. The investigators also observed change in microbiome and circulating metabolites. The current study will determine whether or not the addition of anti-inflammatory diet improves the clinical outcomes in participants with rheumatoid arthritis, and the role of microbiome and circulating metabolites.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/07/2024
Locations: UCSD, La Jolla, California
Conditions: Rheumatoid Arthritis
Effect of Anti-inflammatory (ITIS) Diet in Knee Osteoarthritis
Recruiting
To study the effect of anti-inflammatory diet on clinical and biological outcomes in patients with knee osteoarthritis
Gender:
All
Ages:
18 years and above
Trial Updated:
05/07/2024
Locations: UCSD, La Jolla, California
Conditions: Osteoarthritis, Knee
Conventional Instrumentation, Computer Navigation, and Robotic Assistance Techniques in TKA
Recruiting
Knee osteoarthritis is a debilitating disease that can cause severe knee pain and significant limitations to patients' activities of daily living. Total knee arthroplasty (TKA), also known as knee replacement surgery, is a well-established and successful procedure for treatment of end-stage knee osteoarthritis. Over the years, TKA surgical techniques and implant technology have improved, resulting in better patient outcomes and implant survivorship. Despite continuous improvements being made to... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: UCLA Santa Monica Medical Center, Santa Monica, California
Conditions: Knee Osteoarthritis
AETOS Shoulder System
Recruiting
The goal of this study is to confirm the safety and performance of the AETOS Shoulder System for USA adoption. This is a prospective, open, adaptive, non-comparative, multi-centre investigation enrolling a maximum of 220 subjects in 2 cohorts (anatomic and reverse) at up to 15 sites. No intra-study comparator group will be included, and there will be no randomization
Gender:
All
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: California Pacific Orthopedics, San Francisco, California
Conditions: Shoulder Osteoarthritis, Shoulder Arthritis
Use of Acthar in Rheumatoid Arthritis (RA) Related Flares
Recruiting
This is a Rheumatoid Arthritis (RA) study. The purpose of this research study is to determine in RA flare, whether musculoskeletal ultrasound (MSUS) inflammatory scores and/or disease activity scores improve with Acthar treatment.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/04/2024
Locations: UCLA David Geffen School of Medicine, Division of Rheumatology, Los Angeles, California
Conditions: Rheumatoid Arthritis (RA)
Defining the Molecular and Radiologic Phenotype of Progressive RA Interstitial Lung Disease
Recruiting
A study to identify patients with Rheumatoid Arthritis - Associated Interstitial Lung Disease (RA-ILD) that are at the highest risk for progression. The goal of the investigators is to recruit a group of patients with RA-ILD and collect information to help us understand more about disease progression. The investigators will do this using a combination of clinical, radiologic, and biologic features.
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
04/29/2024
Locations: University of California San Francisco, San Francisco, California
Conditions: Rheumatoid Arthritis, Interstitial Lung Disease
The Effect of Adipose-Derived Stem Cells for Knee Osteoarthritis
Recruiting
The purpose of this study is to compare the clinical and functional outcomes of patients with mild to moderate arthroscopically confirmed osteoarthritis between the following two groups: Partial fat pad harvest with Adipose-Derived Stem Cell (ADSC) transplantation with standard arthroscopic treatment consisting of: partial meniscectomy, cartilage stabilization, loose body removal and selective synovectomy. Standard arthroscopic treatment (above) without cell transplant.
Gender:
All
Ages:
Between 35 years and 70 years
Trial Updated:
04/24/2024
Locations: Kerlan Jobe Orthopedic Institute, Santa Monica, California +1 locations
Conditions: Knee Osteoarthritis
PREDICT Therapy Selection for JAK, T-cell, or IL-6 Inhibitor Therapies Using a Molecular Signature Response Classifier (PREDICT)
Recruiting
Prospective, multi-center-observational study conducted within the US, collecting patient samples for research and development to train, test, and validate precision medicine classifiers. These molecular signature response classifiers (MSRC) aim to predict response status to JAK, T-cell, and IL-6 inhibitor therapies in patients with rheumatoid arthritis (RA).
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
04/24/2024
Locations: Medvin Clinical Research//Amicus Arthritis, Whittier, California
Conditions: Rheumatoid Arthritis
Comparison of Tc 99m Tilmanocept Imaging With IHC Analysis of CD206 Expression in Synovial Tissue of Subjects With RA
Recruiting
This study is a comparison of quantitative Tc 99m tilmanocept imaging with IHC analysis of CD206 expression in synovial tissue of RA subjects.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/23/2024
Locations: Attune Health, Los Angeles, California
Conditions: Rheumatoid Arthritis