The state of California currently has 75 active clinical trials seeking participants for Arthritis research studies. These trials are conducted in various cities, including Los Angeles, San Francisco, San Diego and Sacramento.
The Effect of Micro Fragmented Adipose Tissue (MFAT) on Shoulder Osteoarthritis
Recruiting
This is a non-surgical trial comparing the clinical and functional outcomes of patients with osteoarthritis treated with Intra-articular injection of Micro Fragmented Adipose Tissue versus conventional therapy of intra-articular injection of corticosteroid.
Gender:
All
Ages:
Between 25 years and 75 years
Trial Updated:
09/15/2023
Locations: Stanford University, Stanford, California
Conditions: Osteoarthritis Shoulder, Shoulder Pain
Autologous Adipose-derived Stromal Vascular Fraction for Treatment of Knee Osteoarthritis
Recruiting
This study is a pivotal study to evaluate the efficacy and safety of a single injection of autologous adipose-derived SVF produced using the GID SVF-2 device system for treatment of pain with concomitant improvement in function associated with osteoarthritis of the knee joint.
Gender:
All
Ages:
Between 35 years and 85 years
Trial Updated:
09/07/2023
Locations: UC Davis, Sacramento, California
Conditions: Osteoarthritis, Knee
Genicular Artery Embolization Vs Observation for Symptomatic Knee Osteoarthritis
Recruiting
The purpose of this clinical trial is to determine whether genicular artery embolization (GAE) is an effective way to treat knee pain from osteoarthritis. Pain from arthritis is often due to underlying inflammation in the joint. The inflammation is associated with increased abnormal blood flow going to the specific area of pain. If the investigator can reduce the blood flow, the inflammation can be reduced and the pain can be controlled. The GAE procedure is an experimental procedure to decreas... Read More
Gender:
All
Ages:
Between 40 years and 79 years
Trial Updated:
08/29/2023
Locations: UCLA Santa Monica Hospital, Santa Monica, California
Conditions: Knee Osteoarthritis, Degenerative Joint Disease of Knee
The Effect of Guided Care With Vectra Compared to Treatment as Usual in Patients With Rheumatoid Arthritis
Recruiting
The goal of treating patients diagnosed with rheumatoid arthritis (RA) is to achieve remission or low disease activity and thereby prevent joint damage, loss of physical function, and disability. Optimal management requires regular assessment of disease activity, with treatment changes made as needed for optimal efficacy. Vectra is a blood serum test that looks at 12 biomarkers and produces a score on a scale of 1 to 100. The Vectra score has been shown to be the strongest predictor of risk for... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/07/2023
Locations: Bio Solutions Clinical Research, La Mesa, California +2 locations
Conditions: Rheumatoid Arthritis (RA)
Anti-Inflammatory Dietary Intervention for Rheumatoid Arthritis
Recruiting
The primary objective of this study is to assess if there is a significant difference in the mean disease activity score in individuals with RA participating in a dietary intervention compared to those in the control group measured by DAS-28. Other measures to track disease activity will include monitoring number and severity of disease flares and any changes in medications. This will be done by completing a single-blinded randomized controlled trial, parallel in design. The study population wil... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/18/2023
Locations: Attune Health Research Inc, Beverly Hills, California
Conditions: Rheumatoid Arthritis
OTIS Autoimmune Diseases in Pregnancy Project
Recruiting
The purpose of the OTIS Autoimmune Diseases in Pregnancy Study is to monitor planned and unplanned pregnancies exposed to certain medications, to evaluate the possible teratogenic effect of these medications and to follow live born infants for five years after birth. With respect to fetal outcome, it is important to evaluate the spectrum of outcomes that may be relevant to a medication exposure during pregnancy, and these include both easily recognizable defects which are visible at birth, as we... Read More
Gender:
Female
Ages:
All
Trial Updated:
05/22/2023
Locations: University of California, San Diego, San Diego, California
Conditions: Crohn's Disease, Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis, Psoriasis
Stelara and Tremfya Pregnancy Exposure Registry OTIS Autoimmune Diseases in Pregnancy Project
Recruiting
The purpose of the OTIS Autoimmune Diseases in Pregnancy Study is to monitor planned and unplanned pregnancies exposed to certain medications, to evaluate the possible teratogenic effect of these medications and to follow live born infants for one year after birth. With respect to fetal outcome, it is important to evaluate the spectrum of outcomes that may be relevant to a medication exposure during pregnancy, and these include both easily recognizable defects which are visible at birth, as well... Read More
Gender:
Female
Ages:
All
Trial Updated:
05/22/2023
Locations: University of California, San Diego, La Jolla, California
Conditions: Psoriasis, Pregnancy, Psoriatic Arthritis, Crohn Disease
Prevalence of Pathogens in Synovial Fluid Obtained From Emergency Department Patients
Recruiting
This is a prospective, observational study of patients presenting to the emergency departments at 9 EMERGEncy ID NET sites. The objectives of the proposed study are to: Describe the range and proportion of infectious agents in synovial fluid as detected by standard C&S and investigational PCR testing, i.e., Biofire® Film Array® Bone and Joint Infection (BJI) Panel, Describe the epidemiology of patients receiving diagnostic arthrocentesis and those diagnosed with septic arthritis in the emergenc... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/01/2023
Locations: Olive View-UCLA Medical Center, Sylmar, California
Conditions: Septic Arthritis, Joint Infection
Physica System Total Knee Replacement Registry Study
Recruiting
The primary objective of this study is to obtain long-term implant survivorship (out to 10 years) and to assess clinical, patient-reported outcome measures, and radiographic data for the commercially available Physica system. For ancillary arm, from baseline to 5-year follow-up.
Gender:
All
Ages:
22 years and above
Trial Updated:
03/17/2023
Locations: Eisenhower Desert Orthopedics Center - Harry and Diane Rinker Bldg, Rancho Mirage, California
Conditions: Osteoarthritis, Knee, Traumatic Arthritis, Avascular Necrosis, Degenerative Joint Disease of Knee, Rheumatoid Arthritis, Deformity of Knee
Comparative Effectiveness of Particulate Versus Nonparticulate Steroid Injections for Musculoskeletal Conditions
Recruiting
This aims of this study are: To determine if particulate or non-particulate corticosteroid injections are more effective at treating pain from musculoskeletal pathologies of the hip, glenohumeral joint, biceps tendon, or subacromial/subdeltoid bursa at 2 weeks, 3 months, or 6 months. To determine if there is a significantly different side effect profile between particulate and non-particulate corticosteroids when used for hip, glenohumeral joint, biceps tendon, or subacromial/subdeltoid bursa i... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/17/2023
Locations: Stanford University, Redwood City, California
Conditions: Osteoarthritis, Tendinopathy, Impingement Shoulder
Validity of AI in Treatment of the Musculoskeletal Conditions by Vifive
Recruiting
The purpose of this study is to evaluate the efficacy of the 12-week ViFive program, a vision-based artificial intelligent digital care plan for chronic knee pain. ViFive digital care plan is delivered by a physical therapy team consisting of physical therapists and a personal coach. We aim to understand the safety and efficacy of this vision artificial intelligent based home exercise program.
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
03/17/2023
Locations: Stanford University Hospitals and Clinics, Redwood City, California
Conditions: Shoulder Adhesive Capsulitis, Knee Osteoarthritis
Pain Relief After Trapeziectomy: Ibuprofen & Acetaminophen Versus Oxycodone
Recruiting
In the US, pain management after surgery for surgical treatment of osteoarthritis at the base of the thumb typically consists of prescription opioids during the early recovery phase. Given the highly addictive nature of prescription opioids, guidelines are being evaluated by hand surgeons to reduce opioid use while still maintaining pain control after surgery. A promising approach is to use non-narcotic medication as the first line of treatment. The purpose of this study is to demonstrate the ef... Read More
Gender:
All
Ages:
45 years and above
Trial Updated:
01/31/2023
Locations: Stanford Health Care, Redwood City, California
Conditions: Pain, Postoperative, Osteoarthritis Thumb