The state of California currently has 56 active clinical trials seeking participants for COVID19 research studies. These trials are conducted in various cities, including Los Angeles, San Francisco, San Diego and Sacramento.
A CHW Intervention to Identify and Decrease Barriers to COVID 19 Testing & Vaccination
Recruiting
The objective of this study is to compare the results of a COVID-19 specific curriculum led by LACDHS Community Health Workers (CHWs) from these same communities of safety-net patients to effectively increase COVID-19 testing and vaccination for individual patients, and to facilitate needed healthcare in a timely manner for the safety net health system, and to develop a sustained public health presence in these communities to build trust and preparedness for critical COVID-19 related future need... Read More
Gender:
All
Ages:
16 years and above
Trial Updated:
02/28/2023
Locations: Los Angeles Department of Public Health, Los Angeles, California +1 locations
Conditions: Vaccine Hesitancy, COVID-19 Testing, Community Health Workers
CArdiac REhabilitation for Building Exertional heArt Rate for Chronotropic Incompetence in Long COVID-19
Recruiting
The goal of this proof-of-concept clinical trial is to determine whether cardiac rehabilitation improves exercise capacity and chronotropic (heart rate) response to exercise among people with Long COVID. The study will include individuals with confirmed SARS-CoV-2 infection, symptoms not present prior to COVID-19 that are persistent for at least 3 months after acute infection ("Long COVID"), and who have reduced exercise capacity less than predicted and reduced heart rate response during cardiop... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/29/2022
Locations: University of California, San Francisco, San Francisco, California
Conditions: Long COVID, COVID-19
A Phase II Study in Patients With Moderate to Severe ARDS Due to COVID-19
Recruiting
This is a Phase II multi-center, double-blind, placebo-controlled, randomized study in Patients with moderate to severe lung injury due to COVID-19 or other potential viral and bacterial pathogens.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/07/2022
Locations: Providence Medical Foundation, Fullerton, California +1 locations
Conditions: Covid19
Point-of-care Lung Ultrasound (POCUS)-Integrated Study of Admitted Patients With COVID-19
Recruiting
This study seeks to define the ultrasound profile of patients with COVID-19, and document the progression of these ultrasound findings to develop prognostication and clinical decision instruments that can help guide management of patient with COVID-19. Primary aims include the development of ARDS, refractory hypoxemia, acute cardiac injury, pulmonary embolism, pneumothorax or death. Secondary aims include potential change in CT and plain film utilization given the use of POCUS, as well as emerge... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/22/2022
Locations: UCLA-Ronald Reagan, Los Angeles, California +1 locations
Conditions: Lung Injury, ARDS, Acute Cardiac Event, Covid19, Ultrasound, Hypoxemia, Acute Respiratory Distress Syndrome
POC Study to Evaluate the Performance of the AcuVid COVID-19 Rapid Antigen Saliva Test
Recruiting
The AcuVid COVID-19 Rapid Antigen Saliva Test is a lateral flow immunoassay to detect SARS-CoV-2 nucleocapsid antigens in human saliva specimens from individuals suspected of COVID-19 by their healthcare provider within the first seven days of symptom onset, or from individuals without symptoms or other epidemiological reasons to suspect. The AcuVid COVID-19 Rapid Antigen Saliva Test performance will be compared to a high sensitivity FDA EUA approved RT-PCR COVID-19 test. Nasopharyngeal (for RT... Read More
Gender:
All
Ages:
12 years and above
Trial Updated:
12/21/2021
Locations: Covid Clinic Inc., Modesto, California
Conditions: COVID-19
Single-Blind Study of STAT-205 in Mild COVID-19
Recruiting
This is a randomized, single blind, study. Males and females meeting inclusion criteria who have symptoms of mild COVID-19 and in whom a positive PCR result for SARS-CoV-2 is obtained may be enrolled to the study treatment within 72 hours of the positive PCR result. Eligible patients are those considered to be at high risk for COVID-19 disease progression. This includes patients ≥ 65 years of age or with any one or more of certain medical conditions including: cancer, COPD, cardiovascular diseas... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/07/2021
Locations: Loma Linda University, Loma Linda, California
Conditions: COVID-19
COVID-19 Administration of Single-Dose Subcutaneous Anti- Spike(s) SARS-CoV-2 Monoclonal Antibodies Casirivimab and Imdevimab in High-Risk Pediatric Participants Under 12 Years of Age
Recruiting
The primary objective of the study is to characterize the concentrations of casirivimab+imdevimab in serum over time after a single subcutaneous (SC) administration The secondary objectives of the study are: To assess the safety and tolerability of SC or single administration of casirivimab+imdevimab To assess the occurrence of grade ≥3 injection site reactions and grade ≥3 hypersensitivity reactions, in participants treated with SC doses of casirivimab+imdevimab To assess the immunogenicity o... Read More
Gender:
All
Ages:
12 years and below
Trial Updated:
12/06/2021
Locations: Advanced Research Center, Inc, Anaheim, California
Conditions: COVID-19
A Study to Explore the Role of Gut Flora in COVID-19 Infection
Recruiting
This study seeks to determine whether the virus which causes COVID-19, SARS-CoV-2, is shed in the stools of patients who are infected.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/02/2021
Locations: ProgenaBiome, Ventura, California
Conditions: Gut Microbiome, Gastrointestinal Microbiome, COVID, COVID-19, Corona Virus Infection, Coronavirus, Coronaviridae Infections, Coronavirus 19, Coronavirus-19, COVID 19