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                    Heart Diseases Clinical Trials
A listing of 30  Heart Diseases  clinical trials  actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
            1 - 12 of 30
        
                There are currently 30 active clinical trials seeking participants for Heart Diseases research studies. The states with the highest number of trials for Heart Diseases participants are New York, Pennsylvania, California and Texas.
            
                Featured Trial
                
                Healthy Participants Needed (Colonoscopy + Cancer Screening)
            
        Recruiting
            
        Earn $325 - $475 in electronic payment card compensation for your time and effort by participating in a clinical study to develop a blood test that may one day help screen for colon cancer. Take a quick quiz to see if you qualify.
    
    
                            Conditions: 
                                    
        
            
                        Healthy
                    
                                    
                        Healthy Volunteers
                    
                                    
                        Healthy Subjects
                    
                                    
                        Healthy Volunteer
                    
                                    
                        Healthy Participants
                    
                                    Featured Offer
                
                Lose Weight with GLP-1 Medications
            
        Recruiting
            
        Policy Lab has partnered with OnlineSemaglutide.org to offer trusted access to semaglutide and other GLP-1 medications, including generic alternatives to Ozempic® and Wegovy®. 
GLP-1 medications are scientifically backed to help individuals achieve significant weight loss—on average, 15-20% of body weight within a year.
As a valued user, you’re eligible for $50 off your first program with code policy-lab-50.
    GLP-1 medications are scientifically backed to help individuals achieve significant weight loss—on average, 15-20% of body weight within a year.
As a valued user, you’re eligible for $50 off your first program with code policy-lab-50.
                            Conditions: 
                                    
        
            
                        Overweight
                    
                                    
                        Overweight and Obesity
                    
                                    
                        Obesity
                    
                                    
                        Weight Loss
                    
                                    
                        Morbid Obesity
                    
                                    Featured Trial
                
                Dilated Cardiomyopathy (DCM) Research Study
            
        Recruiting
            
        If you are identified as eligible for investigational genetic testing, you will be sent a saliva collection kit to your home. Once you have completed and returned your kit to Sano Genetics, your sample will be tested for a specific genetic pathway called BAG3.
Investigational genetic testing can help you better understand your body and its needs, as well as how DCM may be passed down in your family. Those who are identified as having a variant in the BAG3 gene will be referred to an upcoming clinical trial.
    Investigational genetic testing can help you better understand your body and its needs, as well as how DCM may be passed down in your family. Those who are identified as having a variant in the BAG3 gene will be referred to an upcoming clinical trial.
                            Conditions: 
                                    
        
            
                        Dilated Cardiomyopathy (DCM)
                    
                                    
                        Cardiovascular Diseases
                    
                                    
                        Cardiomyopathy
                    
                                    
                        Cardiovascular Disease
                    
                                    
                        Heart Failure
                    
                                    Featured Trial
                
                Stroke Clinical Study
            
        Recruiting
            
        A clinical study for people that suffer with Stroke
    
    
                            Conditions: 
                                    
        
            
                        Stroke
                    
                                    
                
                                    Two-Year Study of the Safety and Efficacy of the Second-Generation Tissue Engineered Vascular Grafts
                                
            
            
        Recruiting
                            
            
                A single arm clinical trial evaluating the safety and efficacy of the second generation TEVG as vascular conduits for extracardiac total cavopulmonary connection.             
        
        
    Gender:
                ALL
            Ages:
                All
            Trial Updated:
                06/24/2025
            
            Locations: Nationwide Children's Hospital, Columbus, Ohio         
        
        
            Conditions: HLH - Hypoplastic Left Heart Syndrome, DORV, DILV - Double Inlet Left Ventricle, Mitral Atresia, Tricuspid Atresia, Unbalanced AV Canal, Single-ventricle, Heart Defects, Congenital, Cardiovascular Abnormalities, Cardiovascular Diseases, Heart Diseases
        
            
        
    
                
                                    IPSC Repository of Pediatric Cardiovascular Disease
                                
            
            
        Recruiting
                            
            
                Obtain blood samples for generation and maintenance of induced pluripotent stem cells (iPSCs) and genomic/DNA sequencing for biomedical research that will improve the understanding and treatment of pediatric cardiovascular disease             
        
        
    Gender:
                ALL
            Ages:
                All
            Trial Updated:
                02/22/2025
            
            Locations: Nationwide Children's Hospital, Columbus, Ohio         
        
        
            Conditions: Congenital Heart Disease, Heart Diseases
        
            
        
    
                
                                    The PulsePoint Study
                                
            
            
        Recruiting
                            
            
                This randomized controlled trial will evaluate whether use of the PulsePoint system increases bystander CPR or defibrillator use compared to standard dispatch procedures in patients who suffer non-traumatic, out-of-hospital cardiac arrest in a public location. Half of all suspected cardiac arrest 9-1-1 calls in a public location will receive PulsePoint alerts (treatment arm). The other half of this eligible patient cohort will receive standard dispatch procedures (control arm).             
        
        
    Gender:
                ALL
            Ages:
                All
            Trial Updated:
                11/20/2024
            
            Locations: Columbus Division of Fire, Columbus, Ohio  +2 locations         
        
        
            Conditions: Out-Of-Hospital Cardiac Arrest, Heart Arrest, Heart Diseases, Cardiovascular Diseases
        
            
        
    
                
                                    The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMR
                                
            
            
        Recruiting
                            
            
                The objective of this prospective, randomized, blinded clinical trial is to assess the safety and efficacy of the Carillon Mitral Contour System in treating heart failure with functional regurgitation (FMR).             
        
        
    Gender:
                ALL
            Ages:
                18 years and above
            Trial Updated:
                08/22/2025
            
            Locations: Dignity Health Research Institute at Mercy Gilbert and Chandler Regional Medical Centers, Gilbert, Arizona  +70 locations         
        
        
            Conditions: Functional Mitral Regurgitation, Heart Failure, Mitral Valve Insufficiency, Heart Diseases, Cardiovascular Diseases, Heart Valve Diseases
        
            
        
    
                
                                    Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
                                
            
            
        Recruiting
                            
            
                The purpose of TEAM-HF IDE clinical trial is to evaluate safety and effectiveness of the HeartMate 3 LVAS compared to guideline directed medical therapy (GDMT) in a population of ambulatory advanced heart failure patients who are not dependent on intravenous inotrope.             
        
        
    Gender:
                ALL
            Ages:
                18 years and above
            Trial Updated:
                08/08/2025
            
            Locations: Banner-University Medical Center Phoenix, Phoenix, Arizona  +42 locations         
        
        
            Conditions: Heart Failure, Heart Diseases, Cardiovascular Diseases, Pulmonary Hypertension
        
            
        
    
                
                                    Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
                                
            
            
        Recruiting
                            
            
                Transthyretin amyloidosis (ATTR) is a disease where the normally occurring transthyretin (TTR) protein falls apart and forms amyloid, a sticky plaque- like substance that accumulates in different organs in the body and can cause damage to the organ. There are two ways that the TTR protein can fall apart. One way occurs as a person ages, where the normal TTR protein can fall apart and form amyloid that may no longer be sufficiently cleared by the body. This type of ATTR is known as wild-type ATTR...  Read More             
        
        
    Gender:
                ALL
            Ages:
                Between 18 years and 75 years
            Trial Updated:
                08/04/2025
            
            Locations: University of California, San Diego (UCSD) - Medical Center, La Jolla, California  +37 locations         
        
        
            Conditions: Amyloidosis, Amyloid Cardiomyopathy, Transthyretin Amyloidosis, Cardiomyopathies, Heart Diseases, Polyneuropathies
        
            
        
    
                
                                    Gauging Outcomes of Total Milk Ingestion on Lipid and gControl
                                
            
            
        Recruiting
                            
            
                Atherosclerotic cardiovascular disease remains the leading cause of death for adults in the United States. The cardiovascular impact of milk consumption remains a matter of long-standing scientific debate. Current guidelines for Americans recommend three daily servings of fat-free or low-fat (1%) dairy over full-fat options due to concerns that saturated fat may increase cardiovascular risk. Yet, the literature does not consistently support non-fat dairy as superior to high-fat dairy for reducin...  Read More             
        
        
    Gender:
                ALL
            Ages:
                18 years and above
            Trial Updated:
                07/28/2025
            
            Locations: UCSF Medical Center at Parnassus, San Francisco, California         
        
        
            Conditions: Heart Diseases, Cardiovascular Disease
        
            
        
    
                
                                    Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
                                
            
            
        Recruiting
                            
            
                The goal of this study is to evaluate the safety and efficacy of the BrioVAD System by demonstrating non-inferiority to the HeartMate 3 Left Ventricular Assist System when used for the treatment of advanced, refractory, left ventricular heart failure.             
        
        
    Gender:
                ALL
            Ages:
                Between 18 years and 100 years
            Trial Updated:
                07/02/2025
            
            Locations: Emory University, Atlanta, Georgia  +9 locations         
        
        
            Conditions: Cardiovascular Diseases, Heart Diseases, Heart Failure
        
            
        
    
                
                                    Insertable Cardiac Monitor-Guided Early Intervention to Reduce Atrial Fibrillation Burden Following Catheter Ablation
                                
            
            
        Recruiting
                            
            
                To prospectively investigate the efficacy of an insertable cardiac monitor-guided atrial fibrillation (AF) management in reducing subsequent AF burden in patients with persistent or paroxysmal AF undergoing atrial catheter ablation (CA).             
        
        
    Gender:
                ALL
            Ages:
                18 years and above
            Trial Updated:
                06/30/2025
            
            Locations: University of Rochester Medical Center, Rochester, New York         
        
        
            Conditions: Atrial Fibrillation, Cardiovascular Diseases, Heart Diseases, Arrhythmias, Cardiac, Pathologic Processes
        
            
        
    
                
                                    Sapphire 3 CTO Study
                                
            
            
        Recruiting
                            
            
                A prospective, open label, multi-center, single arm, observational study designed to evaluate the acute safety and device performance of the Sapphire 3 0.85, 1.0 and 1.25mm diameter coronary dilatation catheter in predilatation of Chronic Total Occlusion (CTO) lesions during percutaneous coronary intervention.
One hundred seventy (170) subjects will be enrolled with a target of one hundred fifty-three (153) evaluable subjects by the angiographic core laboratory at up to 15 clinical sites with t...  Read More             
        
        
    Gender:
                ALL
            Ages:
                18 years and above
            Trial Updated:
                06/03/2025
            
            Locations: Stanford Health Care, Stanford, California  +13 locations         
        
        
            Conditions: Coronary Artery Disease, Coronary Disease, Myocardial Ischemia, Heart Diseases, Arteriosclerosis, Cardiovascular Diseases, Chronic Total Occlusion, Chronic Total Occlusion of Coronary Artery
        
            
        
    
                
                                    Smart Walk: A Culturally Tailored Smartphone-Delivered Physical Activity Intervention for African American Women
                                
            
            
        Recruiting
                            
            
                The purpose of this study is to test a culturally tailored, smartphone-delivered intervention designed to increase physical activity and reduce risk for heart disease and type 2 diabetes among African American women.             
        
        
    Gender:
                FEMALE
            Ages:
                Between 24 years and 65 years
            Trial Updated:
                05/15/2025
            
            Locations: Arizona State University, Phoenix, Arizona         
        
        
            Conditions: Physical Activity, Exercise, Heart Diseases, Diabetes Mellitus, Physical Inactivity
        
            
        
    
                
                                    American Indian Chronic Renal Insufficiency Cohort Study (AI-CRIC Study)
                                
            
            
        Recruiting
                            
            
                Despite many advances in our understanding of the natural history and progression of chronic kidney disease (CKD) and cardio vascular disease (CVD) in the parent CRIC study over the past 15 years, important questions about key risk factors for these diseases remain unanswered in the AI population. To address this burden of CKD in AI communities Investigators formed a consortium of investigators with extensive experience in conducting research of chronic diseases including diabetes, cardiovascula...  Read More             
        
        
    Gender:
                ALL
            Ages:
                Between 21 years and 80 years
            Trial Updated:
                05/14/2025
            
            Locations: NIDDK-Phoenix Epidemiology and Clinical Research, Phoenix, Arizona  +2 locations         
        
        
            Conditions: Diabetes Mellitus, Chronic Kidney Diseases, Heart Diseases, Cardiovascular Diseases
        
            
        
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