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Heart Diseases Clinical Trials
A listing of 36 Heart Diseases clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
1 - 12 of 36
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There are currently 36 active clinical trials seeking participants for Heart Diseases research studies. The states with the highest number of trials for Heart Diseases participants are New York, Pennsylvania, California and Texas.
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Featured Trial
Studying an Investigational Virus Vaccine
Recruiting
The main objectives of this study are to assess the safety and effectiveness of an investigational vaccine aimed at preventing norovirus, commonly known as the stomach flu. Participants will be randomly assigned to receive either the investigational vaccine or a placebo. Should you express interest, you will be contacted directly by the research site, which will provide further details and answer any questions you may have about study requirements, risks/benefits, and any compensation.
Conditions:
Healthy
Interested in vaccine studies
All Conditions
Preventative Trials
Featured Trial
Respiratory Syncytial Virus (RSV) Treatment Study
Recruiting
We’re seeking volunteers to participate in a RSV treatment study.
Our site is now enrolling ages 18+ years old in a research study evaluating an investigational RSV treatment. Compensation is available for participation. To be eligible, you must be 18 or older, experiencing current symptoms (such as nasal congestion, cough, or wheezing), and meet at least one of the following:
- Asthma
- Chronic lung disease
- COPD
- Heart disease
- Age 60 or older
Our site is now enrolling ages 18+ years old in a research study evaluating an investigational RSV treatment. Compensation is available for participation. To be eligible, you must be 18 or older, experiencing current symptoms (such as nasal congestion, cough, or wheezing), and meet at least one of the following:
- Asthma
- Chronic lung disease
- COPD
- Heart disease
- Age 60 or older
Conditions:
RSV
Respiratory Syncytial Virus (RSV)
Healthy
Healthy Volunteers
Healthy Subjects
Featured Trial
Evaluating an Investigational Treatment for Hidradenitis Suppurativa
Recruiting
The main objectives of this Phase 2 study are to evaluate the safety and effectiveness of an investigational medication in adults with moderate to severe hidradenitis suppurativa (HS), a chronic skin condition. Participants will be randomly assigned to receive the investigational treatment or a placebo. Should you express interest, the research site will contact you directly to provide further details and address any questions you may have about study requirements, risks/benefits, and compensation.
Conditions:
All Conditions
Hidradenitis suppurativa (Skin disorder)
Dermatology
The PulsePoint Study
Recruiting
This randomized controlled trial will evaluate whether use of the PulsePoint system increases bystander CPR or defibrillator use compared to standard dispatch procedures in patients who suffer non-traumatic, out-of-hospital cardiac arrest in a public location. Half of all suspected cardiac arrest 9-1-1 calls in a public location will receive PulsePoint alerts (treatment arm). The other half of this eligible patient cohort will receive standard dispatch procedures (control arm).
Gender:
ALL
Ages:
All
Trial Updated:
11/20/2024
Locations: Columbus Division of Fire, Columbus, Ohio +2 locations
Conditions: Out-Of-Hospital Cardiac Arrest, Heart Arrest, Heart Diseases, Cardiovascular Diseases
Two-Year Study of the Safety and Efficacy of the Second-Generation Tissue Engineered Vascular Grafts
Recruiting
A single arm clinical trial evaluating the safety and efficacy of the second generation TEVG as vascular conduits for extracardiac total cavopulmonary connection.
Gender:
All
Ages:
All
Trial Updated:
05/03/2024
Locations: Nationwide Children's Hospital, Columbus, Ohio
Conditions: HLH - Hypoplastic Left Heart Syndrome, DORV, DILV - Double Inlet Left Ventricle, Mitral Atresia, Tricuspid Atresia, Unbalanced AV Canal, Single-ventricle, Heart Defects, Congenital, Cardiovascular Abnormalities, Cardiovascular Diseases, Heart Diseases
iPSC Repository of Pediatric Cardiovascular Disease
Recruiting
Obtain blood samples for generation and maintenance of induced pluripotent stem cells (iPSCs) and genomic/DNA sequencing for biomedical research that will improve the understanding and treatment of pediatric cardiovascular disease
Gender:
All
Ages:
All
Trial Updated:
02/05/2024
Locations: Nationwide Children's Hospital, Columbus, Ohio
Conditions: Congenital Heart Disease, Heart Diseases
Effectiveness of CRD-4730 in Participants with Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)
Recruiting
This is a Phase 2, multicenter, double-blind, sponsor unblinded, placebo-controlled, single-dose clinical study of CRD-4730 to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of CRD-4730 when administered as single oral doses to participants with Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT). The study will have 2 cohorts in which participants with CPVT will participate in a 3-period, randomized 2-sequence study. Each participant will receive 2... Read More
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
01/17/2025
Locations: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio +10 locations
Conditions: CPVT1, Heart Defects, Congenital, Heart Diseases, Ventricular Tachycardia
Safety & Effectiveness of Tovinontrine in Chronic Heart Failure With Preserved Ejection Fraction (Cycle-2-PEF)
Recruiting
The purpose of this study is to evaluate the safety and effectiveness of tovinontrine compared to placebo to lower NT-proBNP in patients with chronic heart failure with preserved ejection fraction
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/18/2025
Locations: Cardurion Investigative Site, Birmingham, Alabama +65 locations
Conditions: Heart Failure, Heart Failure Preserved Ejection Fraction, Cardiovascular Diseases, Heart Diseases
A Study to Assess Safety & Effectiveness of Tovinontrine in Chronic Heart Failure With Reduced Ejection Fraction (Cycle-1-REF)
Recruiting
The purpose of this study is to evaluate the safety and effectiveness of tovinontrine compared to placebo to lower NT-proBNP in patients with chronic heart failure with reduced ejection fraction.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/18/2025
Locations: Cardurion Investigative Site, Birmingham, Alabama +92 locations
Conditions: Heart Failure, Heart Failure With Reduced Ejection Fraction, Cardiovascular Diseases, Heart Diseases
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
Recruiting
Transthyretin amyloidosis (ATTR) is a disease where the normally occurring transthyretin (TTR) protein falls apart and forms amyloid, a sticky plaque- like substance that accumulates in different organs in the body and can cause damage to the organ. There are two ways that the TTR protein can fall apart. One way occurs as a person ages, where the normal TTR protein can fall apart and form amyloid that may no longer be sufficiently cleared by the body. This type of ATTR is known as wild-type ATTR... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
02/07/2025
Locations: MedStar Washington Hospital Center - MedStar Heart and Vascular Institute, Washington, District of Columbia +4 locations
Conditions: Amyloidosis, Amyloid Cardiomyopathy, Transthyretin Amyloidosis, Cardiomyopathies, Heart Diseases, Polyneuropathies
Trial to Evaluate Safety and Effectiveness of Mechanical Circulatory Support in Patients with Advancing Heart Failure
Recruiting
The purpose of TEAM-HF IDE clinical trial is to evaluate safety and effectiveness of the HeartMate 3 LVAS compared to guideline directed medical therapy (GDMT) in a population of ambulatory advanced heart failure patients who are not dependent on intravenous inotrope.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/05/2025
Locations: Baptist Health Medical Center, Little Rock, Arkansas +8 locations
Conditions: Heart Failure, Heart Diseases, Cardiovascular Diseases, Pulmonary Hypertension
The 1200 Patients Project: Studying the Implementation of Clinical Pharmacogenomic Testing
Recruiting
The purpose of this study is to collect DNA samples from patients undergoing routine care at the University of Chicago. These samples will be tested for differences in genes that may suggest greater risk of side effects or chance of increased benefit from certain medications. The results will be made available to the patient's treating physician and the researchers will track whether or not this information is used in routine health care.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/04/2025
Locations: University of Chicago Medical Center, Chicago, Illinois
Conditions: Patients Undergoing Routine Health Care, Heart Diseases, Inflammatory Bowel Diseases, Autoimmune Disease, Inflammatory Disease, Blood Coagulation Disorders, Hepatitis C, Non-Metastatic Neoplasm
Prescribed Sternal Precautions vs. Self-Guided Restrictive Care (PEEERC)
Recruiting
Our study aims to compare postoperative outcomes, postoperative pain and postoperative quality of lives in patients who receive the standard sternal precautions to those in patients who received self-managed sternal precautions following sternotomy for cardiac surgeries. The purpose of the study is to see if self-managed sternal precautions following sternotomy for cardiac surgeries lead to better quality of lives while maintaining same postoperative pain and rate of postoperative adverse events... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
02/03/2025
Locations: The University of Chicago, Chicago, Illinois
Conditions: Surgery, Heart Diseases, Heart Failure, Cardiac Valve Disease
Development of a Culturally Tailored Resilience-building Intervention for Chinese American's Advance Care Planning Discussions
Recruiting
Less than 15% of Chinese Americans complete advance directives. That is less than half of the 37% completion rate in the US general population. This disparity in the use of advance care planning between White Americans and Chinese Americans may extend to disparities in end-of-life care. To address such disparities in end-of-life care, we will develop and assess the acceptability of a culturally tailored resilience-building intervention to help Chinese Americans with cancer or heart disease and t... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
01/17/2025
Locations: University of Illinois Chicago, Chicago, Illinois
Conditions: Advance Care Planning, Neoplasms, Heart Diseases
Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
Recruiting
The goal of this study is to evaluate the safety and efficacy of the BrioVAD System by demonstrating non-inferiority to the HeartMate 3 Left Ventricular Assist System when used for the treatment of advanced, refractory, left ventricular heart failure.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
01/15/2025
Locations: Emory University, Atlanta, Georgia +6 locations
Conditions: Cardiovascular Diseases, Heart Diseases, Heart Failure
1 - 12 of 36