There are currently 35 active clinical trials seeking participants for Heart Diseases research studies. The states with the highest number of trials for Heart Diseases participants are New York, Pennsylvania, California and Texas.
Exparel vs. Marcaine ESP Block for Post-cardiac Surgical Pain
NCT06077422
Recruiting
The goal of this pilot study is to describe and compare Ultrasound-Guided Erector Spinae Plane (ESP) Blocks using Exparel® (bupivacaine liposome injectable suspension) to Marcaine® (bupivacaine hydrochloride) for pain management and outcomes after cardiac surgeries.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/24/2024
Locations: Rutgers RWJMS, New Brunswick, New Jersey
Conditions: Pain, Postoperative, Opioid Use, Perioperative Complication, Heart Diseases
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Safety and Efficacy Study of reSept ASD Occluder for Treating Secundum ASD
NCT04591392
Recruiting
Evaluation of the safety and efficacy of the reSept ASD Occluder to treat patients with clinically significant secundum atrial septal defect
Gender:
All
Ages:
84 years and below
Trial Updated:
12/21/2023
Locations: Children's Hospital of Los Angeles, Los Angeles, California +27 locations
Conditions: Heart Septal Defect, Heart Septal Defects, Atrial, Heart Defects, Congenital, Cardiovascular Abnormalities, Cardiovascular Diseases, Heart Diseases, Congenital Abnormalities
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Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women
NCT04124120
Recruiting
The central hypothesis of ROMA:Women is that the use of multiple arterial grafting (MAG) will improve clinical outcomes and quality of life (QOL) compared to single arterial grfating (SAG). The specific aims of ROMA:Women are: Aim 1: Determine the impact of MAG vs SAG on major adverse cardiac and cerebrovascular events in women undergoing coronary artery bypass grfating (CABG). The investigators will compare major adverse cardiac and cerebrovascular events (death, stroke, non-procedural myocar... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
12/19/2023
Locations: Cedars-Sinai Medical Center, Los Angeles, California +102 locations
Conditions: Heart Diseases, Coronary Artery Disease, Coronary Artery Bypass Grafting
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Dairy Fat and Fermentation Study
NCT05840081
Recruiting
The purpose of the study is to compare the effect of consuming full-fat (regular) and fat-free (skim) milk, as well as full-fat and fat-free yogurt (a fermented dairy product), on microorganisms in your gut as well as the products produced by the gut microbes. We will also determine whether consuming these dairy products affects risk factors for heart disease.The findings of the study will help us determine if heart disease risk factors are modified by the fat content and fermentation of milk. T... Read More
Gender:
All
Ages:
50 years and above
Trial Updated:
12/18/2023
Locations: Jean Mayer Human Nutrition Research Center on Aging, Boston, Massachusetts
Conditions: Heart Diseases, Microbial Colonization, Inflammation
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Reducing Sedentary Time in Patients With Cardiovascular Disease
NCT05534256
Recruiting
The purpose of this study is to develop and test a 12-week sedentary behavior reduction intervention ("Sit Less" program) for patients with cardiovascular disease. The program aims to reduce and break sitting times among this population using an objective activity monitor and mHealth. The investigators will test the program to help cardiovascular disease patients break up sitting time, reduce daily sitting time, and move more. The investigators will also study whether the program leads to improv... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/09/2023
Locations: Vanderbilt University, Nashville, Tennessee
Conditions: Cardiovascular Diseases, Heart Diseases, Sedentary Behavior, Physical Activity
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Insertable Cardiac Monitor-Guided Early Intervention to Reduce Atrial Fibrillation Burden Following Catheter Ablation
NCT04922281
Recruiting
To prospectively investigate the efficacy of an insertable cardiac monitor-guided atrial fibrillation (AF) management in reducing subsequent AF burden in patients with persistent or paroxysmal AF undergoing atrial catheter ablation (CA).
Gender:
All
Ages:
18 years and above
Trial Updated:
09/05/2023
Locations: University of Rochester Medical Center, Rochester, New York
Conditions: Atrial Fibrillation, Cardiovascular Diseases, Heart Diseases, Arrhythmias, Cardiac, Pathologic Processes
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South Asians and Coronary Plaque Registry
NCT05367297
Recruiting
Individuals who self-report as SAs will be recruited to participate in this registry as well as non-SA controls for comparison. All individuals who consent to participate will 1) complete a survey assessing demographics, medical history, family medical history; 2) have blood collection; 3) and CCTA assessment. These data will be combined with clinical data from the electronic health record and, if applicable, the Dallas Hearts and Mind Study and other research studies, for research purposes. The... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/18/2023
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Coronary Artery Disease, Heart Diseases
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Personalized Responses to Dietary Composition Trial 3
NCT04735835
Recruiting
The PREDICT 3 study will build on previous research in over 2,000 individuals to further refine machine learning models that predict individual responses to foods, with the aim of advancing precision nutrition science and individualized dietary advice. The study incorporates both standardized and controlled dietary intervention, for the purpose of testing postprandial responses to specific mixed meals, in addition to a free-living period with a dietary record for measuring responses to a large v... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/28/2023
Locations: Zoe US Inc., Needham, Massachusetts +1 locations
Conditions: Diabetes, Heart Diseases, Diet Habit, Diet Modification, Healthy, Obesity, Metabolism, Microbial Colonization
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Ammonia N-13 Myocardial Blood Flow Absolute Quantification by PET in Patients With Known or Suspected CAD (Ammonia MAP)
NCT04343209
Recruiting
This study is being conducted to provide access to and collect test data for an established nuclear medicine diagnostic imaging test called Positron Emission Tomography (PET), using a specific radioactive drug called Ammonia N-13 (Ammonia), referred to simply as an Ammonia PET scan, which is used to visualize the blood flow through the blood vessels and into the heart muscle in order to identify areas of restricted blood flow within the heart. The scanner used in this study may be a stand-alone... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/06/2023
Locations: Doral Imaging Institute, LLC DBA CIRA Miami Beach, Miami Beach, Florida +4 locations
Conditions: Myocardial Ischemia, Coronary Disease, Coronary Artery Disease, Heart Diseases, Cardiovascular Diseases, Arteriosclerosis, Arterial Occlusive Diseases, Vascular Diseases
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An Ascending Dose Comparison of MVT-100 to Definity in Healthy Volunteers
NCT03882359
Recruiting
Definity (perflutren lipid microspheres, Lantheus Medical Imaging) is an ultrasound contrast indicated for use in patients with suboptimal echocardiograms to opacify the left ventricular chamber and to improve the delineation of the left ventricular endocardial border. MVT-100 (the investigational pharmaceutical) is similar to Definity, with the exception of the removal of one lipid in the lipid blend and substitution of another lipid. This study is intended to evaluate the safety and efficacy o... Read More
Gender:
All
Ages:
19 years and above
Trial Updated:
03/30/2023
Locations: Saint Luke's Hospital of Kansas City, Kansas City, Missouri +1 locations
Conditions: Heart Diseases
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Evaluation of CCR2 in Patients Post Myocardial Infarction
NCT05107596
Recruiting
To determine the feasibility of 64Cu-DOTA-ECL1i, an investigational PET imaging drug, at the cellular level in the myocardium for individuals who have suffered a heart attack or who have other inflammatory heart disease.
Gender:
All
Ages:
Between 21 years and 80 years
Trial Updated:
11/22/2022
Locations: Washington University School of Medicine, Saint Louis, Missouri
Conditions: Heart Diseases
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