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All Clinical Trials
A listing of 23118 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
1 - 12 of 23118
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Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
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Recruiting
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Conditions:
Overweight
Overweight and Obesity
Obesity
Weight Loss
Morbid Obesity
Children s Growth and Behavior Study
Recruiting
Background:
- Studies show that many factors affect children's eating behavior and health. These include sleep, mood, thinking skills, and genetics. Studying children over time may identify children at higher risk for eating-related health concerns.
Objective:
- To understand how genes and environment influence eating behavior and health over time.
Eligibility:
- Children ages 8-17 in good general health.
Design:
* Screening visit 1: Medical history, physical exam, body measurements, and... Read More
Gender:
ALL
Ages:
Between 8 years and 100 years
Trial Updated:
06/18/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Obesity, Eating Behaviors, Healthy Volunteers
Pomalidomide and Nivolumab in People With Virus-Associated Malignancies With or Without HIV
Recruiting
Background:
Less toxic and more effective treatments are needed for cancers caused by viruses. These cancers include Hodgkin and non-Hodgkin lymphoma, hepatocellular carcinoma, head and neck cancer, nasopharyngeal carcinoma, gastric cancer, anal cancer, cervical cancer, vaginal cancer, vulvar cancer, penile cancer, Merkel cell carcinoma, Kaposi sarcoma, and leiomyosarcoma. Researchers want to see if a combination of drugs can help.
Objective:
To find a safe dose of pomalidomide plus nivolumab... Read More
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
06/18/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Viral Associated Malignancies, Kaposi Sarcoma, EBV/KSHV-associated Lymphomas
MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)
Recruiting
This MyeloMATCH Master Screening and Reassessment Protocol (MSRP) evaluates the use of a screening tool and specific laboratory tests to help improve participants' ability to register to clinical trials throughout the course of their myeloid cancer (acute myeloid leukemia or myelodysplastic syndrome) treatment. This study involves testing patients' bone marrow and blood for certain biomarkers. A biomarker (sometimes called a marker) is any molecule in the body that can be measured. Doctors look... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/18/2025
Locations: University of Alabama at Birmingham Cancer Center, Birmingham, Alabama +285 locations
Conditions: Acute Myeloid Leukemia, Myelodysplastic Syndrome
Testing the Impact of Smartphone-based Messaging to Support Young Adult Smoking Cessation
Recruiting
Clinical practice guidelines for smoking cessation emphasize cognitive behavioral therapy (CBT) to help patients develop coping strategies for urges. Mindfulness or Acceptance and Commitment Therapy (ACT) offer a different approach, which teaches smokers psychological flexibility through accepting negative experiences. While there is evidence for the efficacy of both CBT and Mindfulness/ACT smoking cessation interventions, it is unclear if these approaches are efficacious when implemented in rea... Read More
Gender:
ALL
Ages:
Between 18 years and 30 years
Trial Updated:
06/18/2025
Locations: Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland
Conditions: Tobacco Cigarette Smoking
ACP-204 in Adults With Alzheimer's Disease Psychosis
Recruiting
This is a master protocol for 3 independent, seamlessly enrolling, multicenter, randomized, double-blind, placebo-controlled, parallel-group studies in patients with ADP
* Substudy 1 (Phase 2) will evaluate efficacy and dose response of ACP-204 30 and 60 mg vs placebo. This substudy will be initiated first.
* Substudies 2A and 2B (both: Phase 3) will be confirmatory studies of either both doses (ACP-204 30 and 60 mg, respectively) or a single dose from Part 1 vs placebo. Substudies 2A and 2B wi... Read More
Gender:
ALL
Ages:
Between 55 years and 95 years
Trial Updated:
06/18/2025
Locations: Advanced Research Center, Inc., Anaheim, California +119 locations
Conditions: Alzheimer's Disease Psychosis
A Clinical Study of Efinopegdutide in People With Compensated Cirrhosis Due to Steatohepatitis (MK-6024-017)
Recruiting
Researchers are looking for ways to treat a type of liver disease caused by elevated liver fat, called metabolic dysfunction-associated steatohepatitis (MASH). MASH was formerly called non-alcoholic steatohepatitis (NASH). Researchers want to learn if a study medicine called efinopegdutide can treat MASH.The goals of this study are to learn:
* If efinopegdutide can lower the amount of fat, inflammation, and scarring (fibrosis) in the liver
* About the safety of efinopegdutide and how well peopl... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
06/18/2025
Locations: The Institute for Liver Health II dba Arizona Clinical Trial-The Institute for Liver Health ( Site 0149), Chandler, Arizona +61 locations
Conditions: Non-alcoholic Fatty Liver Disease, Nonalcoholic Steatohepatitis, NAFLD, Metabolic Dysfunction-associated Steatotic Liver Disease, Metabolic Dysfunction-associated Steatohepatitis
Efficacy Study of IM Administered CssBA+dmLT Against Moderate-severe Diarrhea in Human Infection Model With ETEC Strain B7A in Healthy Adults
Recruiting
The study is designed to evaluate the safety, immunogenicity, and efficacy of the intramuscular administration of a CS6 based vaccine (CssBA) against ETEC co-administered with double mutant labile toxin (dmLT) in preventing moderate-severe diarrhea (MSD) following challenge with ETEC strain B7A in healthy adults. Approximately 72 adult participants, divided into 4 cohorts of 18, will be randomized 1:1 to receive vaccine (45 micrograms CssBA with 0.5 micrograms dmLT) or placebo (normal saline) on... Read More
Gender:
ALL
Ages:
Between 18 years and 49 years
Trial Updated:
06/18/2025
Locations: University of Maryland, School of Medicine, Center for Vaccine Development and Global Health, Baltimore, Maryland +1 locations
Conditions: Escherichia Infection
A Study of Retatrutide (LY3437943) in the Maintenance of Weight Reduction in Individuals With Obesity
Recruiting
This is a study of retatrutide in participants with obesity. The main purpose is to learn more about how retatrutide maintains body weight loss. The study will have two treatment phases: an 80 week lead-in phase in which all participants will take retatrutide dose 1 and a 36 week randomized, double-blinded phase in which participants will either take retatrutide dose 1, retatrutide dose 2, or switch to placebo. Participation in the study will last around 125 weeks.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/18/2025
Locations: Southern California Clinical Research, Santa Ana, California +52 locations
Conditions: Obesity
Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome
Recruiting
Background:
Severe aplastic anemia (SAA) and myelodysplastic syndrome (MDS) are bone marrow diseases. People with these diseases usually need a bone marrow transplant. Researchers are testing ways to make stem cell transplant safer and more effective.
Objective:
To test if treating people with SAA or MDS with a co-infusion of blood stem cells from a family member and cord blood stem cells from an unrelated donor is safe and effective.
Eligibility:
Recipients ages 4-60 with SAA or MDS
Donor... Read More
Gender:
ALL
Ages:
Between 4 years and 75 years
Trial Updated:
06/18/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Severe Aplastic Anemia, Hypo-Plastic MDS, Myelodysplastic Syndrome (MDS)
Characterization of an Optically Pumped Magnetometer (OPM) Magnetoencephalography (MEG) Array
Recruiting
Background:
Brain activity produces magnetic fields. These fields can be measured outside the head. Existing technology, called MEG, measures these fields. Researchers are testing a new type of magnetic field sensor called OPM. They hope it can help pinpoint with very high accuracy where brain activity is generated.
Objective:
To develop and test a new type of sensor for measuring the magnetic fields produced by brain activity.
Eligibility:
Healthy people ages 18-65 who had a magnetic reson... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
06/18/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Normal Physiology
Safety and Immunogenicity of Recombinant Varicella Zoster Virus Vaccine in People With HIV Who Have a CD4 Count Less Than 300 or Greater Than or Equal to 300 and a Healthy Control Population
Recruiting
Background:
Shingles is a painful, blistering rash caused by the same virus that causes chickenpox. Shingrix is a vaccine approved to prevent shingles in healthy adults over age 50 and in immunocompromised adults over age 18. Researchers want to learn more about how people with HIV respond to Shingrix.
Objective:
To learn how Shingrix affects the immune response in people with HIV.
Eligibility:
People aged 18 years and older with HIV. Healthy people aged 50 years or older are also needed.... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/18/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Herpes Zoster
A Study of Doxycycline to Treat Chlamydial Infection
Recruiting
This is a Phase 4 blinded, randomized, active-controlled, non-inferiority trial. Final evaluable population will include a minimum 596 individuals: 298 women with confirmed urogenital chlamydia (CT) and 298 men with confirmed rectal chlamydia (CT). Approximately 664 participants will be enrolled to achieve a minimum 596 participants who contribute primary outcome data. Randomization will be stratified by study site and sex: 332 women and 332 men. Participants will be randomized 1:1 to a 3-day re... Read More
Gender:
ALL
Ages:
16 years and above
Trial Updated:
06/18/2025
Locations: University of Alabama at Birmingham School of Medicine - Infectious Disease, Birmingham, Alabama +6 locations
Conditions: Chlamydial Infection
1 - 12 of 23118