All Clinical Trials

A listing of 23138 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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Paid Clinical Studies Nationwide

Recruiting

Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.

Conditions:

Healthy

Healthy Volunteer Study

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* Compensation for time may be available

Featured Trial

Type 2 Diabetes Clinical Trial

Recruiting

Can changing your breakfast improve your type 2 diabetes? If you have an HbA1C of 7.0% or higher, you are invited to participate in an online study at the University of Michigan.

Conditions:

Type 2 Diabetes

Diabetes Mellitus Type 2 in Obese

Diabetes Type Two

Type 2 Diabetes Mellitus

Diabete Type 2

Learn More

Featured Offer

Lose Weight with GLP-1 Medications

Recruiting

Policy Lab has partnered with CareGLP to offer trusted access to GLP-1 medications, including generic alternatives to Ozempic® and Wegovy®.

GLP-1 medications are scientifically backed to help individuals achieve significant weight loss—on average, 15-20% of body weight within a year.

As a valued user, you’re eligible for $100 off your first program with code policy-lab-100.

Conditions:

Overweight

Overweight and Obesity

Obesity

Weight Loss

Morbid Obesity

Learn More

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

NCT04613596

Recruiting

The Phase 2 portion of this study evaluates the efficacy and safety of MRTX849 monotherapy and in combination with pembrolizumab in cohorts of patients with advanced NSCLC with KRAS G12C mutation and any PD-L1 TPS and who are candidates for first-line treatment. The Phase 3 portion of the study compares the efficacy of adagrasib in combination with pembrolizumab versus pembrolizumab in patients with unresectable, locally advanced or metastatic squamous or nonsquamous NSCLC with KRAS G12C mutati... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/05/2025

Locations: Local Institution - 007-556-A, Goodyear, Arizona +711 locations

Local Institution - 007-556-A, Goodyear, Arizona

USOR - Arizona Oncology - Prescott Valley, Prescott Valley, Arizona

Local Institution - 007-568-A, Safford, Arizona

Local Institution - 007-568-B, Safford, Arizona

Local Institution - 007-568-C, Safford, Arizona

Local Institution - 007-568-D, Safford, Arizona

Local Institution - 007-568-E, Safford, Arizona

Arizona Clinical Research Center, Tucson, Arizona

Highlands Oncology Group - Springdale, Springdale, Arkansas

Providence - Saint Joseph Home Health - Anaheim, Anaheim, California

The Oncology Institute of Hope and Innovation - Corporate Office, Cerritos, California

Local Institution - 007-777, Fountain Valley, California

Local Institution - 007-778, Laguna Hills, California

Local Institution - 007-898-B, Long Beach, California

MemorialCare - Long Beach Medical Center, Long Beach, California

TRIO - Cancer & Blood Specialty Clinic - Los Alamitos, Los Alamitos, California

Local Institution - 007-579, Los Angeles, California

Local Institution - Unk045, Rancho Mirage, California

San Francisco Veterans Affairs Medical Center, San Francisco, California

UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California

Local Institution - 007-898-C, Santa Ana, California

Providence Medical Group - Santa Rosa, Santa Rosa, California

Stockton Hematology Oncology Medical Group (SHOMG) - Stockton (Suite B), Stockton, California

Local Institution - 007-898-A, Whittier, California

Local Institution - 007-872-H, Aurora, Colorado

Local Institution - 007-872-D, Boulder, Colorado

Local Institution - 007-872-L, Centennial, Colorado

Local Institution - 007-872-C, Colorado Springs, Colorado

Local Institution - 007-872-K, Colorado Springs, Colorado

Local Institution - 007-872-E, Denver, Colorado

Local Institution - 007-872-I, Denver, Colorado

Local Institution - 007-872-A, Lakewood, Colorado

Local Institution - 007-872-J, Littleton, Colorado

USOR - Rocky Mountain Cancer Centers - Lone Tree, Lone Tree, Colorado

Local Institution - 007-872-G, Longmont, Colorado

Local Institution - 007-872-B, Pueblo, Colorado

Local Institution - 007-872-F, Thornton, Colorado

Eastern Connecticut Hematology and Oncology Associates, Norwich, Connecticut

Local Institution - 007-5476, Washington, District of Columbia

GenesisCare USA, Aventura, Florida

Bay Pines Veterans Affairs Healthcare System, Bay Pines, Florida

Local Institution - 007-922-A, Bonita Springs, Florida

Local Institution - 007-922-D, Bradenton, Florida

Local Institution - 007-922-E, Cape Coral, Florida

Local Institution - 007-896-A, Celebration, Florida

Local Institution - 007-926-B, Daytona Beach, Florida

Local Institution - 007-562-B, Fleming Island, Florida

SCRI - Florida Cancer Specialists - South Region Research Office, Fort Myers, Florida

Local Institution - 007-922-B, Fort Myers, Florida

Local Institution - 007-922-C, Fort Myers, Florida

Local Institution - 007-562-F, Jacksonville Beach, Florida

21st Century Oncology of Jacksonville - North Lee Street, Jacksonville, Florida

Local Institution - 007-562-D, Jacksonville, Florida

Local Institution - 007-562-E, Jacksonville, Florida

Local Institution - 007-562-G, Jacksonville, Florida

Local Institution - 007-829, Jacksonville, Florida

Cancer Specialists of North Florida - Southpoint, Jacksonville, Florida

Local Institution - 007-562-C, Jacksonville, Florida

Miami Veterans Affairs Healthcare System, Miami, Florida

Local Institution - 007-922-F, Naples, Florida

Local Institution - 007-922-G, Naples, Florida

AdventHealth Orlando, Orlando, Florida

USOR - Woodlands Medical Specialists, Pensacola, Florida

Local Institution - 007-922-H, Port Charlotte, Florida

Local Institution - 007-562-A, Saint Augustine, Florida

Local Institution - 007-922-I, Sarasota, Florida

Local Institution - 007-922-J, Sarasota, Florida

Local Institution - 007-926-D, Stuart, Florida

Local Institution - 007-924-A, Tallahassee, Florida

SCRI - Florida Cancer Specialists - Tallahassee Cancer Center, Tallahassee, Florida

James A. Haley Veterans Hospital, Tampa, Florida

Local Institution - Unk065, Tampa, Florida

Local Institution - 007-922-L, Venice, Florida

Local Institution - 007-922-K, Venice, Florida

Local Institution - 007-926-C, Vero Beach, Florida

Local Institution - 007-926-A, Wellington, Florida

SCRI - Florida Cancer Specialists - West Palm Beach, West Palm Beach, Florida

Local Institution - Unk072, Weston, Florida

University Cancer & Blood Center (UCBC) - Athens, Athens, Georgia

Local Institution - Unk052, Atlanta, Georgia

Local Institution - 007-786-C, Carrollton, Georgia

Local Institution - 007-786-A, Cartersville, Georgia

Local Institution - 007-786-D, Douglasville, Georgia

Local Institution - 007-786-B, Hiram, Georgia

Central Georgia Cancer Care - Macon, Macon, Georgia

Northwest Georgia Oncology Centers Wellstar - Marietta, Marietta, Georgia

Local Institution - 007-897, Honolulu, Hawaii

Local Institution - Unk005, Honolulu, Hawaii

Local Institution - 007-883-A, Arlington Heights, Illinois

Local Institution - 007-955, Chicago, Illinois

University of Chicago, Chicago, Illinois

Local Institution - 007-064, Maywood, Illinois

USOR - Illinois Cancer Specialists - Niles, Niles, Illinois

Advocate Medical Group Oncology, Park Ridge, Illinois

Local Institution - Unk061, Peoria, Illinois

Goshen Center for Cancer Care, Goshen, Indiana

Local Institution - 007-942-B, Chanute, Kansas

Local Institution - 007-942-D, El Dorado, Kansas

Local Institution - 007-942-E, Independence, Kansas

Local Institution - 007-942-F, Kingman, Kansas

Local Institution - 007-942-G, Liberal, Kansas

Local Institution - 007-942-H, McPherson, Kansas

MidAmerica Cancer Care - Research, Merriam, Kansas

Local Institution - 007-942-I, Newton, Kansas

Local Institution - 007-942-J, Parsons, Kansas

Local Institution - 007-942-K, Pratt, Kansas

Local Institution - 007-942-L, Salina, Kansas

Local Institution - 007-942-M, Wellington, Kansas

Local Institution - Unk032, Westwood, Kansas

Local Institution - 007-942-A, Wichita, Kansas

Cancer Center of Kansas - Wichita - Heritage Plaza, Wichita, Kansas

Local Institution - 007-942-N, Winfield, Kansas

Lexington Medical Cancer Center Hematology/Oncology, Lexington, Kentucky

University of Louisville, Louisville, Kentucky

Local Institution - 007-388-A, Louisville, Kentucky

Local Institution - Unk011, Baton Rouge, Louisiana

Local Institution - 007-994-A, Covington, Louisiana

Pontchartrain Cancer Center - Covington Office, Covington, Louisiana

The Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland

Dana-Farber Cancer Institute, Boston, Massachusetts

Dana-Farber Cancer Institute at St. Elizabeths Medical Center, Brighton, Massachusetts

Brigham and Womens/Mass General Health Care Center at Foxborough, Foxboro, Massachusetts

Dana-Farber Cancer Institute - Merrimack Valley, Methuen, Massachusetts

Dana-Farber Brigham and Womens Cancer Center at Milford Regional, Milford, Massachusetts

Dana-Farber Brigham Cancer Center at South Shore Health, South Weymouth, Massachusetts

USOR - Minnesota Oncology - Burnsville, Burnsville, Minnesota

Local Institution - 007-589A, Edina, Minnesota

Local Institution - Unk006, Minneapolis, Minnesota

Local Institution - 007-822, Minneapolis, Minnesota

Local Institution - 007-830, Rochester, Minnesota

Jackson Oncology Associates - The Hederman Cancer Center, Jackson, Mississippi

Local Institution - 007-590D, Grand Island, Nebraska

Local Institution - 007-590A, Omaha, Nebraska

Local Institution - 007-590B, Omaha, Nebraska

Nebraska Cancer Specialists - Midwest Cancer Center - Legacy, Omaha, Nebraska

Local Institution - 007-590C, Papillion, Nebraska

OptumCare Nevada, Las Vegas, Nevada

Local Institution - 007-938A, Las Vegas, Nevada

Local Institution - 007-938B, Las Vegas, Nevada

Local Institution - 007-993, Belleville, New Jersey

Astera Cancer Care - East Brunswick, East Brunswick, New Jersey

John Theurer Cancer Center, Hackensack, New Jersey

Local Institution - 007-975-A, Somerset, New Jersey

Local Institution - 007-975-B, Somerset, New Jersey

Local Institution - 007-975-C, Somerset, New Jersey

Local Institution - 007-975-D, Somerset, New Jersey

Holy Name Medical Center, Teaneck, New Jersey

New York Oncology Hematology - Albany Medical Center, Albany, New York

Montefiore Medical Center, Bronx, New York

Local Institution - Unk077, Rhinebeck, New York

Duke University Medical Center, Durham, North Carolina

Local Institution - 007-893-B, Cincinnati, Ohio

USOR - Oncology Hematology Care - Blue Ash, Cincinnati, Ohio

Local Institution - 007-893-C, Cincinnati, Ohio

University Hospitals Cleveland Medical Center, Cleveland, Ohio

Mark H. Zangmeister Cancer Center, Columbus, Ohio

Local Institution - 007-893-A, Fairfield, Ohio

Kettering Health Cancer Center - Main Campus, Kettering, Ohio

USOR - Willamette Valley Cancer Institute and Research Center - Eugene, Eugene, Oregon

Local Institution - 007-885B, Portland, Oregon

Local Institution - 007-885A, Portland, Oregon

Oregon Oncology Specialists, Salem, Oregon

Local Institution - 007-885C, Tigard, Oregon

Local Institution - Unk041, Allentown, Pennsylvania

Veterans Affairs Pittsburgh Healthcare System - University Drive Campus, Pittsburgh, Pennsylvania

Local Institution - 007-960, Providence, Rhode Island

Local Institution - Unk038, Charleston, South Carolina

Local Institution - 007-5475, Spartanburg, South Carolina

Avera Cancer Institute, Sioux Falls, South Dakota

Local Institution - 007-928-L, Dickson, Tennessee

Local Institution - 007-928-J, Franklin, Tennessee

Local Institution - 007-928-G, Gallatin, Tennessee

West Cancer Center & Research Institute - East Campus, Germantown, Tennessee

Local Institution - 007-928-A, Hendersonville, Tennessee

Local Institution - 007-928-D, Hermitage, Tennessee

Local Institution - 007-928-H, Lebanon, Tennessee

Local Institution - 007-928-F, Murfreesboro, Tennessee

Local Institution - 007-928-B, Nashville, Tennessee

Tennessee Oncology - Nashville - Centennial Clinic - Medical Oncology, Nashville, Tennessee

Local Institution - 007-928-K, Nashville, Tennessee

Local Institution - 007-928-E, Nashville, Tennessee

Local Institution - 007-928-C, Nashville, Tennessee

Local Institution - 007-928-M, Shelbyville, Tennessee

Local Institution - 007-928-I, Smyrna, Tennessee

Local Institution - 007-554B, Abilene, Texas

Local Institution - 007-554G, Amarillo, Texas

Local Institution - 007-879-A, Arlington, Texas

Local Institution - 007-879-B, Arlington, Texas

Local Institution - 007-892-B, Austin, Texas

Local Institution - 007-892-A, Austin, Texas

USOR - Texas Oncology - Dallas Fort Worth (DFW) - South Austin, Austin, Texas

Local Institution - 007-879-C, Bedford, Texas

Local Institution - Unk059, Dallas, Texas

Local Institution - 007-592, Dallas, Texas

Texas Oncology - Dallas Fort Worth (DFW) - Baylor Charles A. Sammons Cancer Center, Dallas, Texas

USOR - Texas Oncology Northeast Texas - Denison, Denison, Texas

Local Institution - 007-554E, El Paso, Texas

Local Institution - 007-554C, El Paso, Texas

Local Institution - 007-554F, El Paso, Texas

USOR - Texas Oncology - Fredericksburg, Fredericksburg, Texas

Local Institution - 007-848, Houston, Texas

Local Institution - 007-999, Irving, Texas

Local Institution - 007-890-B, Longview, Texas

Local Institution - 007-554A, Midland, Texas

USOR - Texas Oncology - Dallas Fort Worth (DFW) - Odessa West Texas Cancer Center, Odessa, Texas

USOR - Texas Oncology - The Woodlands, The Woodlands, Texas

Local Institution - 007-890-A, Tyler, Texas

Local Institution - 007-554D, Wichita Falls, Texas

Local Institution - 007-912, Salt Lake City, Utah

Local Institution - 007-814-A, Alexandria, Virginia

Local Institution - 007-814-D, Arlington, Virginia

USOR - Virginia Cancer Specialists - Fairfax Office, Fairfax, Virginia

Local Institution - 007-814-B, Gainesville, Virginia

Local Institution - 007-814-C, Leesburg, Virginia

Virginia Cancer Institute - West End, Richmond, Virginia

USOR - Northwest Cancer Specialists, P.C. dba Compass Oncology - Vancouver Cancer Center, Vancouver, Washington

Local Institution - Unk064, Huntington, West Virginia

Local Institution - Unk057, Madison, Wisconsin

Local Institution - Unk068, Madison, Wisconsin

Local Institution - 007-5001, Belgrano, Buenos Aires

Local Institution - Unk043, Ciudad Autonoma De Buenos Aires, Buenos Aires

Local Institution - 007-5004, Rosario, Santa Fe

Local Institution - Unk053, Buenos Aires, Not set

Local Institution - Unk033, Porto Alegre, Not set

Local Institution - Unk020, Rio Cuarto, Not set

Ballarat Regional Integrated Cancer Center, Ballarat, Not set

Flinders Medical Centre, Bedford Park, Not set

Local Institution - 007-004, Clayton, Not set

Canberra Hospital, Garran, Not set

Local Institution - 007-1003, Hyde Park, Not set

Local Institution - 007-1002, Port Macquarie, Not set

Cancer Care Wollongong, Wollongong, Not set

Princess Alexandra Hospital, Woolloongabba, Not set

Klinikum Klagenfurt Am Worthersee, Klagenfurt Am Woerthersee, Not set

Ordensklinikum Linz Elisabethinen, Linz, Not set

Wiener Gesundheitsverbund - Klinik Floridsdorf, Wien, Not set

Universitair Ziekenhuis Antwerpen, Edegem, Not set

Algemeen Ziekenhuis Maria Middelares, Gent, Not set

Jessa Ziekenhuis - Campus Virga Jesse, Hasselt, Not set

Local Institution - 007-152, Roeselare, Not set

Local Institution - 007-458, Natal, Rio Grande Do Norte

Local Institution - Unk050, Lajeado, Rio Grande Do Sul

Local Institution - Unk015, Porto Alegre, Rio Grande Do Sul

Local Institution - Unk060, Barretos, Not set

Local Institution - Unk002, Ijui, Not set

Local Institution - Unk003, Rio de Janeiro, Not set

Local Institution - Unk019, Sao Jose Do Rio Preto, Not set

Local Institution - Unk074, Sao Paolo, Not set

Multiprofile Hospital For Active Treatment - Dr. Tota Venkova, Gabrovo, Not set

Specialized Hospital for Active Oncology Treatment - Haskovo SLLC (SBALO - Haskovo - EOOD), Haskovo, Not set

Complex Oncology Center - Plovdiv - Base II, Plovdiv, Not set

University Multiprofile Hospital for Active Treatment St. Ivan Rilski, Sofia, Not set

Complex Oncology Center - Vratsa, Vratsa, Not set

Cross Cancer Institute, Edmonton, Alberta

British Columbia Cancer Agency - Vancouver, Vancouver, British Columbia

Local Institution - 007-489, London, Ontario

Ottawa Hospital - General Campus, Ottawa, Ontario

Princess Margaret Cancer Centre, Toronto, Ontario

Local Institution - 007-490, Montreal, Quebec

Local Institution - Unk028, Santiago, Not set

Local Institution - Unk073, Temuco, Not set

Local Institution - 007-051, Bengbu, Anhui

The First Affiliated Hospital of Bengbu Medical College/Department of Respiratory and Critical Care Medicine, Bengbu, Anhui

Local Institution - 007-026-Ph2, Hefei, Anhui

Local Institution - 007-026, Hefei, Anhui

Local Institution - 007-739-Ph2, Hefei, Anhui

Local Institution - 007-739, Hefei, Anhui

Local Institution - 007-747-Ph3, Hefei, Anhui

Local Institution - 007-747, Hefei, Anhui

Cancer Hospital Chinese Academy of Medical Sciences/Medical Oncology Department, Beijing, Beijing

Local Institution - 007-050, Beijing, Beijing

Local Institution - 007-707-Ph2, Beijing, Beijing

Local Institution - 007-707, Beijing, Beijing

Local Institution - 1025-Ph2, Beijing, Beijing

Local Institution - 1025, Beijing, Beijing

Beijing Cancer Hospital/No.1 Thoracic Oncology Department, Beijing, Beijing

Beijing Cancer Hospital/Thoracic Oncology(2nd) Department, Beijing, Beijing

Beijing Cancer hospital, Beijing, Beijing

Local Institution - 007-027-Ph2, Beijing, Beijing

Local Institution - 007-038, Beijing, Beijing

Local Institution - 007-040-Ph2, Beijing, Beijing

Local Institution - 007-040, Beijing, Beijing

Local Institution - 007-718-Ph3, Chongqing, Chongqing

Local Institution - 1029-Ph2, Chongqing, Chongqing

Local Institution - 1029, Chongqing, Chongqing

Local Institution - 007-053-Ph3, Chongqing, Chongqing

Local Institution - 007-053, Chongqing, Chongqing

Local Institution - 1046-Ph2, Fuzhou, Fujian

Local Institution - 1046, Fuzhou, Fujian

Fujian Cancer Hospital/Thoracic Oncology Department, Fuzhou, Fujian

Fujian Cancer Hospital, Fuzhou, Fujian

Local Institution - 007-039, Fuzhou, Fujian

Local Institution - 007-714-Ph2, Xiamen, Fujian

Local Institution - 007-714, Xiamen, Fujian

Local Institution - 007-732-Ph2, Xiamen, Fujian

Local Institution - 007-732-Ph3, Xiamen, Fujian

Local Institution - 007-732, Xiamen, Fujian

Local Institution - 1022-Ph2, Guangzhou, Guangdong

Local Institution - 1022, Guangzhou, Guangdong

Local Institution - 007-712, Guangzhou, Guangdong

The First Affiliated Hospital of Guangzhou Medical University/Oncology Department, Guangzhou, Guangdong

The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong

Local Institution - 007-705-Ph2, Guangzhou, Guangdong

Local Institution - 007-705, Guangzhou, Guangdong

Nanfang Hospital, Southern Medical University/Respiratory Medicine Department, Guangzhou, Guangdong

Local Institution - 007-052, Shenzhen, Guangdong

Shenzhen People's Hospital/Department of Respiratory and Critical Care Medicine, Shenzhen, Guangdong

Local Institution - 007-704-Ph2, Liuzhou, Guangxi

Local Institution - 007-704, Liuzhou, Guangxi

Guangxi Medical University Cancer Hospital/Department of Respiratory Oncology, Nanning, Guangxi

Local Institution - 007-384, Nanning, Guangxi

Local Institution - 007-744-Ph2, Nanning, Guangxi

Local Institution - 1038-Ph2, Nanning, Guangxi

Local Institution - 1038, Nanning, Guangxi

Local Institution - 007-742-Ph3, Shijiazhuang, Hebei

Local Institution - 007-742, Shijiazhuang, Hebei

Local Institution - 007-028-Ph2, Harbin, Heilongjiang

Local Institution - 007-028-Ph3, Harbin, Heilongjiang

Local Institution - 007-028, Harbin, Heilongjiang

Local Institution - 1012-Ph2, Xinxiang, Henan

Local Institution - 007-021-Ph3, Zhengzhou, Henan

Local Institution - 007-730-Ph3, Zhengzhou, Henan

Local Institution - 1010-Ph2, Zhengzhou, Henan

Local Institution - 1010, Zhengzhou, Henan

Local Institution - 007-021-Ph2, Zhengzhou, Henan

Local Institution - 007-715-Ph2, Zhengzhou, Henan

Local Institution - 007-715, Zhengzhou, Henan

Local Institution - 007-730-Ph2, Zhengzhou, Henan

Local Institution - 007-719-Ph2, Wuhan, Hubei

Union Hospital Affiliated with Tongji Medical College of Huazhong University of Science and Technology/Cancer Center Department, Wuhan, Hubei

Local Institution - 007-700-Ph2, Wuhan, Hubei

Local Institution - 007-700, Wuhan, Hubei

Local Institution - 007-701-Ph2, Changsha, Hunan

Hunan Cancer Hospital/Thoracic Medicine Department II, Changsha, Hunan

Local Institution - 007-706-Ph3, Nanjing, Jiangsu

Local Institution - 1021-Ph2, Nanjing, Jiangsu

Local Institution - 1021, Nanjing, Jiangsu

Nanjing First Hospital/Respiratory Department, Nanjing, Jiangsu

Local Institution - 1018-Ph2, Nanjing, Jiangsu

Local Institution - 1018, Nanjing, Jiangsu

Local Institution - 1020-Ph2, Nanjing, Jiangsu

Local Institution - 1020, Nanjing, Jiangsu

Local Institution - 1004-Ph2, Nantong, Jiangsu

Local Institution - 1004, Nantong, Jiangsu

Local Institution - 1017-Ph2, Xuzhou, Jiangsu

Local Institution - 1017, Xuzhou, Jiangsu

Local Institution - 1040-Ph2, Nanchang, Jiangxi

Local Institution - 1040, Nanchang, Jiangxi

The First Affiliated Hospital of Nanchang University/Respiratory and Critical Care Medicine Department, Nanchang, Jiangxi

The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi

Local Institution - 1006-Ph2, Changchun, Jilin

Local Institution - 1006, Changchun, Jilin

Local Institution - 007-717-Ph2, Changchun, Jilin

The First Bethune Hospital Of Jilin University/Oncology Department, Changchun, Jilin

Local Institution - 007-741-Ph2, Shenyang, Liaoning

Local Institution - 007-741, Shenyang, Liaoning

Local Institution - 1008-Ph2, Shenyang, Liaoning

Local Institution - 1008, Shenyang, Liaoning

Local Institution - 007-749-Ph3, Shenyang, Liaoning

Local Institution - 007-749, Shenyang, Liaoning

Liaoning Cancer Hospital & Institute/The 2nd Chest Medical Department, Shenyang, Liaoning

Local Institution - 007-702, Shenyang, Liaoning

Local Institution - 007-746-Ph3, Yinchuan, Ningxia

Local Institution - 007-746, Yinchuan, Ningxia

Local Institution - 007-718-Ph2, Xi'an, Shaanxi

Local Institution - 007-721-Ph2, Xi'an, Shaanxi

Local Institution - 007-721-Ph3, Xi'an, Shaanxi

Local Institution - 007-721, Xi'an, Shaanxi

Local Institution - 007-708-Ph2, Jinan, Shandong

Shandong Cancer Hospital, Jinan, Shandong

Local Institution - 007-737-Ph2, Linyi, Shandong

Linyi Cancer Hospital/Oncology Department, Linyi, Shandong

Local Institution - 007-703-Ph2, Linyi, Shandong

Local Institution - 007-703, Linyi, Shandong

Local Institution - 007-709-Ph2, Shanghai, Shanghai

Local Institution - 007-709, Shanghai, Shanghai

Shanghai Chest Hospital-Oncology department, Shanghai, Shanghai

Fudan University Shanghai Cancer Center/Thoracic Oncology Department, Shanghai, Shanghai

Local Institution - 007-024-Ph2, Shanghai, Shanghai

Local Institution - 007-024-Ph3, Shanghai, Shanghai

Local Institution - 007-024, Shanghai, Shanghai

Local Institution - 007-035-Ph2, Shanghai, Shanghai

Local Institution - 007-740-Ph2, Taiyuan, Shanxi

Local Institution - 007-740, Taiyuan, Shanxi

Local Institution - 007-748-Ph3, Taiyuan, Shanxi

Local Institution - 007-748, Taiyuan, Shanxi

Local Institution - 007-710-Ph2, Chengdu, Sichuan

Local Institution - 007-710, Chengdu, Sichuan

Local Institution - 007-720-Ph2, Chengdu, Sichuan

Sichuan Cancer hospital, Chengdu, Sichuan

West China Hospital of Sichuan University, Chengdu, Sichuan

Local Institution - 007-711-Ph2, Luzhou, Sichuan

Local Institution - 007-711, Luzhou, Sichuan

Local Institution - 007-743-Ph3, Urumchi, Xinjiang

Local Institution - 1036-Ph2, Urumchi, Xinjiang

Local Institution - 1036, Urumchi, Xinjiang

Local Institution - 007-743, Urumqi, Xinjiang

Local Institution - 1032-Ph2, Kunming, Yunnan

Local Institution - 1032, Kunming, Yunnan

Local Institution - 007-385-Ph3, Kunming, Yunnan

Local Institution - 007-385, Kunming, Yunnan

Local Institution - 007-745-Ph2, Kunming, Yunnan

Local Institution - 007-745, Kunming, Yunnan

Local Institution - 007-716-Ph2, Hangzhou, Zhejiang

Local Institution - 007-716, Hangzhou, Zhejiang

Local Institution - 007-716-Ph3, Hangzhou, Zhejiang

Local Institution - 007-036-Ph2, Hangzhou, Zhejiang

Local Institution - 007-036, Hangzhou, Zhejiang

Zhejiang Cancer Hospital/Thoracic Medicine Department, Hangzhou, Zhejiang

Zhejiang Cancer Hospital, Hangzhou, Zhejiang

Local Institution - 1050-Ph2, Taizhou, Zhejiang

Local Institution - 1050, Taizhou, Zhejiang

Taizhou Hospital Of Zhejiang Province, Taizhou, Zhejiang

Local Institution - 1043-Ph2, Qingdao, Not set

Local Institution - 1043, Qingdao, Not set

Local Institution - 007-035, Shanghai, Not set

Local Institution - Unk021, Medellin, Not set

Local Institution - Unk027, Monteria, Not set

Local Institution - 007-4000, Pula, Not set

Local Institution - 007-4001, Rijeka, Not set

Local Institution - 007-4002, Zagreb, Not set

Multiscan - Ambulance klinicke onkologie se stacionarem - Horovice, Horovice, Not set

Fakultni Nemocnice Olomouc, Olomouc, Not set

Nemocnice AGEL Ostrava-Vitkovice, Ostrava, Not set

Local Institution - 007-163, Praha 2, Not set

Fakultni nemocnice Bulovka, Praha 8 - Liben, Not set

Local Institution - 007-172, Odense, Not set

Local Institution - 007-173, Soenderborg, Not set

Local Institution - 007-170, Vejle, Not set

Local Institution - 007-183, Helsinki, Not set

Local Institution - 007-182, Tampere, Not set

Local Institution - 007-689, Angers Cedex 02, Not set

Local Institution - 007-1992, Boulogne-Billancourt, Not set

Local Institution - 007-194, Brest, Not set

Local Institution - 007-196, Caen Cedex 5, Not set

Local Institution - 007-190, Creteil, Not set

Local Institution - 007-683, La Tronche, Not set

Local Institution - 007-195, Limoges cedex, Not set

Local Institution - 007-199, Marseille, Not set

Local Institution - 007-687, Marseille, Not set

Local Institution - 007-200, Montpellier, Not set

Local Institution - 007-666, Mulhouse, Not set

Local Institution - 007-664, Paris cedex 05, Not set

Local Institution - 007-1991, Rennes cedex 9, Not set

Local Institution - 007-198, Saint Herblain, Not set

Local Institution - 007-1990, Saint Herblain, Not set

Local Institution - 007-684, Strasbourg cedex, Not set

Local Institution - 007-209, Tours Cedex 9, Not set

Local Institution - 007-202, Villejuif, Not set

Local Institution - 007-790, Batumi, Not set

Local Institution - 007-065, Tbilisi, Not set

Local Institution - 007-795, Tbilisi, Not set

Local Institution - 007-789, Tbilisi, Not set

Local Institution - 007-063, Tbilisi, Not set

Institute of Clinical Oncology - Tbilisi, Tbilisi, Not set

Local Institution - 007-211A, Immenstadt, Bayern

Local Institution - 007-675, Amberg, Not set

Local Institution - 007-2222, Augsburg, Not set

Klinikum Chemnitz, Chemnitz, Not set

Klinikum Esslingen, Esslingen, Not set

Krankenhaus Nordwest, Frankfurt am Main, Not set

Universitatsklinikum Gieen und Marburg - Gieen, Giessen, Not set

LungenClinic Grosshansdorf, Grohansdorf, Not set

Local Institution - Erdmann, R., Hamburg, Not set

Local Institution - 007-677, Heidelberg, Not set

Local Institution - 007-673, Heilbronn, Not set

Lungenklinik Hemer, Hemer, Not set

Local Institution - 007-225, Jena, Not set

Klinikum Kassel, Kassel, Not set

Klinikverbund Allgau - Klinikum Kempten, Kempten, Not set

Local Institution - 007-2217, Koln, Not set

Local Institution - 007-224, Lowenstein, Not set

Universitatsklinikum Schleswig-Holstein - Campus Lubeck, Lubeck, Not set

Local Institution - 007-223, Mainz, Not set

Local Institution - 007-2221, Monchengladbach, Not set

Munchen Klinik Bogenhausen, Munchen, Not set

Local Institution - 007-2218, Neuruppin, Not set

Sana Klinikum Offenbach, Offenbach, Not set

Pius-Hospital Oldenburg, Oldenburg, Not set

Local Institution - 007-2219, Ulm, Not set

Local Institution - 007-502, Athens, Attiki

Local Institution - 007-236, Athens, Not set

Local Institution - 007-238, Heraklion, Not set

Local Institution - 007-235, Larissa, Not set

Local Institution - 007-234, Peiraias, Not set

Local Institution - 007-044, Chai Wan, Not set

Local Institution - 007-041, Hong Kong, Not set

Local Institution - 007-045, Kowloon, Not set

Semmelweis Egyetem - Pulmonologiai Klinika, Budapest, Not set

Orszagos Koranyi Pulmonologiai Intezet, Budapest, Not set

Orszagos Onkologiai Intezet, Budapest, Not set

Farkasgyepui Tudogyogyintezet, Farkasgyepu, Not set

Matrai Gyogyintezet, Gyongyos, Not set

Local Institution - 007-057, Tatabanya, Not set

Reformatus Pulmonologiai Centrum, Torokbalint, Not set

Local Institution - 007-1568, Ahemdabad, Not set

Local Institution - 007-1574, Ahmedabad, Not set

Local Institution - 007-1565, Aurangabad, Not set

Local Institution - 007-1586, Bangalore, Not set

Local Institution - 007-1575, Belagavi, Not set

Local Institution - 007-1564, Hyderabad, Not set

Local Institution - 007-1563, Hyderabad, Not set

Local Institution - 007-1569, Jaipur, Not set

Local Institution - 007-1566, Kochi, Not set

Local Institution - 007-1570, Kolkata, Not set

Local Institution - 007-1573, Madurai, Not set

Local Institution - Shetty, R., Mangalore, Not set

Local Institution - 007-1582, Mumbai, Not set

Local Institution - 007-1561, Mysore, Not set

Local Institution - 007-1567, New Delhi, Not set

Local Institution - 007-1578, New Delhi, Not set

Local Institution - 007-1560, Patna, Not set

Local Institution - 007-1571, Pune, Not set

Local Institution - 007-1562, Rajkot, Not set

Local Institution - 007-1581, Varanasi, Not set

Local Institution - 007-256, Cork, Not set

Beaumont Hospital - Dublin, Dublin, Not set

St. Jamess Hospital, Dublin, Not set

Local Institution - 007-251, Dublin, Not set

University Hospital Galway, Galway, Not set

Local Institution - 007-258, Limerick, Not set

University Hospital Waterford, Waterford, Not set

Emek Medical Center, Afula, Not set

Rambam Health Care Campus, Bat Galim, Not set

Soroka Medical Center, Beer Sheva, Not set

Local Institution - 007-263, Holon, Not set

Shaare Zedek Medical Center, Jerusalem, Not set

Hadassah University Hospital Ein Kerem, Jerusalem, Not set

Kaplan Medical Center, Rehovot, Not set

Tel Aviv Sourasky Medical Center, Tel Aviv, Not set

Ziv Medical Center, Zsfat, Not set

Local Institution - Unk016, Aviano, Not set

Istituto Tumori Bari Giovanni Paolo II - IRCCS, Bari, Not set

Azienda Ospedaliero-Universitaria di Bologna - Policlinico Sant Orsola-Malpighi, Bologna, Not set

Azienda Socio Sanitaria Territoriale (ASST) degli Spedali Civili di Brescia, Brescia, Not set

Local Institution - 007-286, Candiolo, Not set

Azienda Ospedaliero - Universitaria Careggi, Firenze, Not set

Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) - Ospedale Policlinico San Martino, Genova, Not set

"Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" - IRST", Meldola, Not set

Fondazione IRCCS - Istituto Nazionale dei Tumori, Milano, Not set

Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) - Ospedale San Raffaele, Milan, Not set

Istituto Europeo di Oncologia, Milan, Not set

Local Institution - 007-318, Monza, Not set

Istituto Nazionale Tumori IRCCS Fondazione G. Pascale, Napoli, Not set

Local Institution - Unk017, Padova, Not set

Azienda Ospedaliero-Universitaria di Parma, Parma, Not set

Azienda Ospedaliera di Perugia - Santa Maria della Misericordia, Perugia, Not set

Azienda Sanitaria Territoriale Pesaro Urbino, Pesaro, Not set

Local Institution - 007-767, Ravenna, Not set

Istituto Nazionale Tumori Regina Elena, Roma, Not set

Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Not set

Local Institution - Unk030, Rozzano, Not set

Ospedale di Circolo e Fondazione Macchi, Varese, Not set

Local Institution - 007-1169, Toon-shi, Ehime

Local Institution - Hattori, Y., Akashi City, Hyogo

Local Institution - Naoki, K., Sagamihara, Kanagawa

Local Institution - 007-1159, Sendai, Miyagi

Local Institution - 007-1592, Nagasaki-shi, Nagasaki

Local Institution - 007-1166, Kashihara, Nara

Local Institution - Okishio, K., Sakai-Shi, Osaka

Fukushima Medical University Hospital, Fukushima-Shi, Not set

National Hospital Organization Iwakuni Clinical Center, Iwakuni, Not set

Jcho Chukyo Hospital, Nagoya, Not set

National Hospital Organization - Nagoya Medical Center, Nagoya, Not set

Local Institution - 007-1591, Nankoku-shi, Not set

Osaka City General Hospital, Osaka, Not set

Local Institution - 007-1167, Osaka, Not set

Local Institution - 007-1164, Toyama, Not set

Pusan National University Hospital, Busan-si, Not set

Inje University Haeundae Paik Hospital, Busan, Not set

Chungbuk National University Hospital, Cheongju-si, Not set

Kyungpook National University Chilgok Hospital, Daegu, Not set

National Cancer Center - Korea, Goyang-si, Not set

Inha University Hospital, Jung-Gu, Not set

Seoul National University Hospital, Seoul, Not set

Severance Hospital, Seoul, Not set

Asan Medical Center, Seoul, Not set

Samsung Medical Center, Seoul, Not set

Local Institution - 007-523, Seoul, Not set

Catholic University of Korea St. Vincents Hospital, Suwon-Si, Not set

Local Institution - Unk079, Johor Bahru, Johor

Local Institution - Choo Khoon, O., George Town, Penang

Local Institution - Unk048, George Town, Penang

Local Institution - Unk007, Petaling Jaya, Selangor

Local Institution - 007-073, Kuala Lumpur, Not set

Local Institution - Unk075, Kuala Lumpur, Not set

Local Institution - Unk034, Mexico, Distrito Federal

Local Institution - Unk049, Mexico, Distrito Federal

Local Institution - Unk070, Guadalajara, Jalisco

Local Institution - Unk037, Monterrey, Not set

Local Institution - Unk026, Monterrey, Not set

Het Nederlands Kanker Instituut, Amsterdam, Not set

Local Institution - 007-308, Den Haag, Not set

Local Institution - 007-633, Dordrecht, Not set

Local Institution - 007-303, Harderwijk, Not set

Local Institution - 007-630, Nijmegen, Not set

Erasmus Medisch Centrum, Rotterdam, Not set

Local Institution - 007-634, Rotterdam, Not set

Universitair Medisch Centrum Utrecht, Utrecht, Not set

Local Institution - 007-305, Zwolle, Not set

Local Institution - Anderson, M., Palmerston North, Not set

Local Institution - 007-310, Drammen, Not set

Local Institution - Unk080, Trujillo, La Libertad

Local Institution - Unk031, Cercado De Lima, Lima

Local Institution - Unk022, Jesus Maria, Lima

Local Institution - Unk024, Miraflores, Lima

Local Institution - Unk042, San Isidro, Lima

Local Institution - Unk071, San Isidro, Lima

Local Institution - Unk054, Surquillo, Lima

Local Institution - Unk051, Arequipa, Not set

Local Institution - Unk023, Arequipa, Not set

Local Institution - Unk044, Arequipa, Not set

Local Institution - Unk040, Cusco, Not set

Local Institution - Unk046, Lima, Not set

Local Institution - 007-1541, Bacolod City, Not set

Local Institution - 007-1545, Cebu City, Not set

Local Institution - 007-1544, Iloilo City, Not set

Local Institution - 007-1543, Makati City, Not set

Local Institution - 007-1542, Molo, Not set

Local Institution - 007-1540, Quezon City, Not set

Uniwersyteckie Centrum Kliniczne w Gdansku, Gdansk, Not set

Swietokrzyskie Centrum Onkologii Samodzielny Publiczny Zaklad Opieki Zdrowotnej, Kielce, Not set

Pratia MCM Krakow, Krakow, Not set

MS Pneumed - Janusz Milanowski, Katarzyna Szmygin-Milanowska Spolka Jawna, Lublin, Not set

Warminsko-mazurskie Centrum Chorob Pluc w Olsztynie, Olsztyn, Not set

Mazowieckie Centrum Leczenia Chorob Pluc I Gruzlicy, Otwock, Not set

Local Institution - 007-389, Poznan, Not set

Pratia Poznan, Skorzewo, Not set

Wojewodzki Szpital Zespolony im. L. Rydygiera w Toruniu, Torun, Not set

Local Institution - 007-056, Warszawa, Not set

Local Institution - 007-322, Warszawa, Not set

Unidade Local de Saude de Coimbra, Coimbra, Not set

Unidade Local de Saude do Alto Ave, E. P. E (Hospital da Senhora da Oliveira Guimaraes), Guimaraes, Not set

Local Institution - 007-338-A, Lisboa, Not set

Local Institution - 007-642, Lisbon, Not set

Hospital CUF Descobertas, Lisbon, Not set

Local Institution - 007-334, Porto, Not set

Unidade Local de Saude de Santo Antonio, E. P. E - Hospital Geral de Santo Antonio, Porto, Not set

Local Institution - 007-339, Porto, Not set

Local Institution - 007-335, Vila Nova de Gaia, Not set

Local Institution - 007-340, Cluj-Napoca, Not set

Local Institution - 007-518, Floreti, Not set

Local Institution - 007-515, Timioara, Not set

Local Institution - 007-693, Belgrade, Not set

Local Institution - 007-694, Kragujevac, Not set

Local Institution - 007-691, Sremska Kamenica, Not set

Local Institution - 007-3515, Uzice, Not set

Local Institution - 007-095, Singapore, Not set

Local Institution - 007-4010, Port Elizabeth, Eastern Cape

Local Institution - 007-4013, Johannesburg, Gauteng

Local Institution - 007-4012, Pretoria, Gauteng

Local Institution - 007-611 A, Pamplona, Navarre

Complejo Hospitalario Universitario A Coruna, A Coruna, Not set

Institut Catala dOncologia Badalona, Badalona, Not set

Hospital de la Santa Creu i Sant Pau, Barcelona, Not set

Hospital Universitari Dexeus, Barcelona, Not set

Hospital Universitari Vall dHebron, Barcelona, Not set

Hospital Clinic de Barcelona, Barcelona, Not set

Local Institution - Unk081, Bilbao, Not set

Local Institution - Unk063, Burgos, Not set

Local Institution - Unk014, Jerez de la Frontera, Not set

Local Institution - 007-628, Las Palmas de Gran Canaria, Not set

Local Institution - Unk012, Leon, Not set

Institut Catala dOncologia - Hospital Duran i Reynals (ICO LHospitalet), LHospitalet de Llobregat, Not set

Clinica Universidad de Navarra - Madrid, Madrid, Not set

Hospital Universitario Ramon y Cajal, Madrid, Not set

Hospital Clinico San Carlos, Madrid, Not set

Hospital Universitario Fundacion Jimenez Diaz, Madrid, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

Hospital Regional Universitario de Malaga - Hospital Civil, Malaga, Not set

Local Institution - 007-604, Santander, Not set

Hospital Clinico Universitario de Santiago, Santiago de Compostela, Not set

Hospital Universitario Virgen del Rocio, Sevilla, Not set

Hospital Clinico Universitario de Valencia, Valencia, Not set

Hospital Universitari i Politecnic La Fe, Valencia, Not set

Local Institution - Unk013, Gavle, Not set

Local Institution - 007-397, Sankt Gallen, Not set

Local Institution - 007-396, Villars-sur-Glane, Not set

Local Institution - 007-128, Taichung City, Not set

Local Institution - 007-127, Taichung, Not set

Taichung Veterans General Hospital, Taichung, Not set

Chi Mei Hospital - Liouying, Tainan City, Not set

Local Institution - 007-122, Tainan, Not set

National Taiwan University Hospital, Taipei City, Not set

Taipei Veterans General Hospital, Taipei City, Not set

Local Institution - 007-129, Taipei City, Not set

Chang Gung Memorial Hospital - Linkou Branch, Taoyuan, Not set

Local Institution - 007-139, Bangkok, Not set

Local Institution - Runglodvatana, Y., Krung Thep Maha Nakhon, Not set

Local Institution - 007-061, Alanya, Not set

Local Institution - 007-096, Altindag, Not set

Hacettepe Universitesi Kanser Enstitusu, Ankara, Not set

Local Institution - 007-3810, Antalya, Not set

Memorial Bahcelievler Hospital, Bahcelievler, Not set

Local Institution - 007-060, Bornova, Not set

Local Institution - 007-055, Cankaya, Not set

Trakya Universitesi Tip Fakultesi, Edirne, Not set

Local Institution - 007-069, Istanbul, Not set

Local Institution - 007-3813, Istanbul, Not set

Izmir Ekonomi Universitesi Medical Point Hastanesi, Izmir, Not set

Local Institution - 007-3811, Kocaeli, Not set

Local Institution - 007-097, Malatya, Not set

Local Institution - 007-068, Mamak, Not set

Local Institution - 007-062, Sisli, Not set

University Hospitals Birmingham NHS Foundation Trust, Birmingham, Not set

Local Institution - 007-415, Edinburgh, Not set

Local Institution - 007-403, Kent, Not set

University Hospitals of Leicester NHS Trust, Leicester, Not set

University College London Hospitals NHS Foundation Trust, London, Not set

Guys and St Thomas NHS Foundation Trust, London, Not set

The Christie NHS Foundation Trust, Manchester, Not set

Royal Surrey County Hospital NHS Foundation Trust, Surrey, Not set

Conditions: Advanced Non-Small Cell Lung Cancer, Metastatic Non-Small Cell Lung Cancer

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A Cardiometabolic Health Program Linked With Clinical-Community Support and Mobile Health Telemonitoring to Reduce Health Disparities

NCT05321368

Recruiting

The LINKED- HEARTS Program is a multi-level project that intervenes at the practice level by linking home blood pressure monitoring (HBPM) with a telemonitoring platform (Sphygmo). The program incorporates team-based care by including community health workers (CHWs) and pharmacists to improve the outcomes of multiple chronic conditions (reduced blood pressure (BP), lower blood sugar, and improved kidney function). The LINKED-HEARTS Program will recruit a total of 600 adults with uncontrolled hyp... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/05/2025

Locations: Unity Health Care, Washington, District of Columbia +2 locations

Conditions: Hypertension, High Blood Pressure, Diabetes, Chronic Kidney Diseases

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Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors

NCT05732831

Recruiting

This is a first in human study in patients with advanced or metastatic solid tumors known to have an MTAP deletion. The first part of the study is an open-label, dose escalation and the second part is an open label dose expansion in specific MTAP-deleted tumor types. The study drug, TNG462, is a selective PRMT5 inhibitor administered orally. The study is planned to treat up to 225 participants.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/05/2025

Locations: Stanford University, Palo Alto, California +24 locations

Stanford University, Palo Alto, California

Grand Valley Oncology, Grand Junction, Colorado

Sylvester Comprehensive Cancer Center, Miami, Florida

University Chicago Medicine, Chicago, Illinois

Carle Cancer Center, Urbana, Illinois

Midwestern Regional Medical Center, City of Hope Chicago, Zion, Illinois

Massachusetts General Hospital, Boston, Massachusetts

Dana Farber Cancer Institute, Boston, Massachusetts

Henry Ford Cancer Center, Detroit, Michigan

New York University Langone Health, New York, New York

Sarah Cannon Tennessee Oncology, Nashville, Tennessee

The University of Texas MD Anderson Cancer Center, Houston, Texas

Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah

Next Oncology Virginia, Fairfax, Virginia

CHU de Brest, Brest, Not set

Centre Berard Leon, Lyon, Not set

Institut de Cancerologie de l'Ouest - Hôpital Saint Herblain - PPDS, Saint-Herblain, Not set

Institute Gustav Roussy, Villejuif, Not set

Vall d'Hebron Barcelona Hospital, Barcelona, Catalonia

Hospital HM Nou Delfos, Barcelona, Not set

ICO l'Hospitalet - Hospital Duran i Reynals, Barcelona, Not set

Hospital Universitario Fundacion Jimenez Diaz, Madrid, Not set

Hospital de Sanchinarro, Madrid, Not set

Hospital Universitario Virgen de la Victoria, Málaga, Not set

Hospital Universitario Virgen del Rocio, Sevilla, Not set

Conditions: Locally Advanced Solid Tumor

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A Study to Evaluate the Safety and the Activity of S095029 as Part of Combination Therapy in Advanced Gastroesophageal Junction/Gastric Cancers.

NCT06116136

Recruiting

This study will investigate the safety, tolerability, and antitumor activity of S095029 (anti-NKG2A antibody) in combination with pembrolizumab in in microsatellite instability-high/Defective mismatch repair (MSI-H/dMMR) locally advanced unresectable or metastatic gastric /GEJ adenocarcinomas.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/05/2025

Locations: Ocala Oncology Center Pl, Ocala, Florida +48 locations

Ocala Oncology Center Pl, Ocala, Florida

Investigative Clinical Research of Indiana, Llc, Noblesville, Indiana

MD Anderson Cancer Center, Houston, Texas

The Queen Elizabeth Hospital, Woodville South, Not set

Ordensklinikum Linz, Linz, Not set

Landeskrankenhaus (SALK), Salzburg, Not set

Med Universitat Wien-Allgemeines Krankenhaus Der Stadt Wien (AKH), Wien, Not set

UZ Leuven Campus Gasthuisberg, Leuven, Not set

Chu de Liege, Liège, Not set

Cepon - Centro de Pesquisas Oncologicas, Florianópolis, Not set

Supera Oncologia, Santa Catarina, Not set

Icesp - Instituto Do Câncer Do Estado de São Paulo, Sao Paulo, Not set

Instituto Brasileiro de Controle Do Câncer, Sao Paulo, Not set

Hospital Albert Einstein, Sao Paulo, Not set

Mount Sinai Hospital, Toronto, Not set

Beijing Cancer Hospital, Beijing, Beijing

Harbin Medical University Cancer Hospital, Harbin, Heilongjiang

Henan Cancer Hospital, Zhengzhou, Henan

Liaoning Cancer Hospital, Shenyang, Liaoning

Shandong Cancer Hospital Institute, Jinan, Shandong

Fudan University Shanghai Cancer Center, Shanghai, Shanghai

Sir Run Run Shaw Hospital Zhejiang University School of Medicine Qingchun Branch, Hangzhou, Zhengjiang Province

Rigshospitalet, Copenhagen, Not set

Odense Universitetshospital, Odense, Not set

Institut Bergonié, Bordeaux, Not set

Centre Georges Francois Leclerc, Dijon, Not set

Chru Lille - Hopital Claude Huriez, Lille, Not set

Inst. de Cancer de L'ouest, Saint Herblain, Not set

Institut Curie, Saint-Cloud, Not set

Institut de Cancerologie de Lorraine, Vandoeuvre-les-Nancy Cedex, Not set

Semmelweis Egyetem, Budapest, Not set

Orszagos Onkologiai Intezet, Budapest, Not set

Bekes Megyei Kozponti Korhaz, Gyula, Not set

Bugat Pal Hospital, Gyöngyös, Not set

A.O.U. Seconda Università Degli Studi Di Napoli, Campania, Not set

Fondazione IRCCS Istituto Nazionale dei Tumor, Milan, Not set

A.O.U. Pisana-Ospedale Santa Chiara, Pisa, Not set

Policlinico Universitario Agostino Gemelli, Rome, Not set

Policlinico G.B. Rossi A.O.U.I. Di Verona, Verona, Not set

Cancer Institute Hospital of Jfcr, Koto-Ku, Tokyo

National Cancer Center Hospital, Chou-ku, Not set

Osaka International Cancer Institute, Osaka, Not set

Pan American Center For Oncology Trials, Llc, Rio Piedras, Not set

University Hospital Vall D'Hebron Institute of Oncology (VHIO), Barcelona, Not set

Hospital Universitario Gregorio Marañón, Madrid, Not set

Hospital Universitario Marqués de Valdecilla, Santander, Not set

Hospital Universitario de Valencia, Valencia, Not set

The Royal Marsden in Chelsea, London, Not set

The Royal Marsden in Sutton, Sutton, Surrey, Not set

Conditions: MSI-H/dMMR Gastroesophageal-junction Cancer, MSI-H/dMMR Gastric Cancer

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Open-label, Long-term Safety Study of Secukinumab in Polymyalgia Rheumatica (PMR)

NCT06331312

Recruiting

The purpose of this extension study is to assess the safety and tolerability of secukinumab when administered long-term in patients with polymyalgia rheumatica.

Gender:

ALL

Ages:

Between 50 years and 100 years

Trial Updated:

05/05/2025

Locations: Arizona Arthritis and Rheumatology Associates PLLC, Avondale, Arizona +80 locations

Arizona Arthritis and Rheumatology Associates PLLC, Avondale, Arizona

Sun Valley Arthritis Center Ltd, Peoria, Arizona

Orrin Troum MD and Medical Associates, Santa Monica, California

Center for Rheumatology Research, West Hills, California

Millennium Clinical Trials, Westlake Village, California

Rheumatology Associates of South Florida, Boca Raton, Florida

Sarasota Arthritis Res Ctr, Sarasota, Florida

West Broward Rheumatology Associates Inc, Tamarac, Florida

Arthritis Center of North Georgia, Gainesville, Georgia

Klein and Associates, Hagerstown, Maryland

Clinical Research Inst of MI, Saint Clair Shores, Michigan

Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire

Prolato Clinical Research Center, Houston, Texas

Accurate Clinical Research Inc, San Antonio, Texas

Advanced Rheumatology of Houston, Spring, Texas

Novartis Investigative Site, Quilmes, Buenos Aires

Novartis Investigative Site, Southport, Queensland

Novartis Investigative Site, Heidelberg Heights, Victoria

Novartis Investigative Site, Parramatta, Not set

Novartis Investigative Site, Quebec, Not set

Novartis Investigative Site, Vina Del Mar, Valparaiso

Novartis Investigative Site, Santiago, Not set

Novartis Investigative Site, Barranquilla, Atlantico

Novartis Investigative Site, Barranquilla, Not set

Novartis Investigative Site, Bogota, Not set

Novartis Investigative Site, Praha 4, Czech Republic

Novartis Investigative Site, Brno, Not set

Novartis Investigative Site, Hlucin, Not set

Novartis Investigative Site, Praha 2, Not set

Novartis Investigative Site, Praha 4, Not set

Novartis Investigative Site, Uherske Hradiste, Not set

Novartis Investigative Site, Zlin, Not set

Novartis Investigative Site, Gandrup, Not set

Novartis Investigative Site, Vejle, Not set

Novartis Investigative Site, Toulon Cedex 9, Val De Marne

Novartis Investigative Site, Brest, Not set

Novartis Investigative Site, Cholet, Not set

Novartis Investigative Site, Colmar Cedex, Not set

Novartis Investigative Site, Dijon, Not set

Novartis Investigative Site, Montpellier 5, Not set

Novartis Investigative Site, Nantes Cedex 1, Not set

Novartis Investigative Site, Reims, Not set

Novartis Investigative Site, Strasbourg, Not set

Novartis Investigative Site, Toulouse, Not set

Novartis Investigative Site, Berlin, Not set

Novartis Investigative Site, Dresden, Not set

Novartis Investigative Site, Herne, Not set

Novartis Investigative Site, Ratingen, Not set

Novartis Investigative Site, Budapest, Not set

Novartis Investigative Site, Szeged, Not set

Novartis Investigative Site, Veszprem, Not set

Novartis Investigative Site, Milano, MI

Novartis Investigative Site, Perugia, PG

Novartis Investigative Site, Pavia, PV

Novartis Investigative Site, Reggio Emilia, RE

Novartis Investigative Site, Fukuoka city, Fukuoka

Novartis Investigative Site, Asahikawa-city, Hokkaido

Novartis Investigative Site, Sagamihara-city, Kanagawa

Novartis Investigative Site, Nagano-city, Nagano

Novartis Investigative Site, Kawachinagano, Osaka

Novartis Investigative Site, Bunkyo ku, Tokyo

Novartis Investigative Site, Fuchu, Tokyo

Novartis Investigative Site, Ome, Tokyo

Novartis Investigative Site, Shimonoseki, Yamaguchi

Novartis Investigative Site, Chuo, Yamanashi

Novartis Investigative Site, Okayama, Not set

Novartis Investigative Site, Ashrafieh, Not set

Novartis Investigative Site, Guadalajara, Jalisco

Novartis Investigative Site, Warszawa, Not set

Novartis Investigative Site, Sabadell, Barcelona

Novartis Investigative Site, Valencia, Comunidad Valenciana

Novartis Investigative Site, La Coruna, Galicia

Novartis Investigative Site, Bilbao, Pais Vasco

Novartis Investigative Site, Madrid, Not set

Novartis Investigative Site, Basel, Not set

Novartis Investigative Site, St Gallen, Not set

Novartis Investigative Site, Hull, Not set

Conditions: Polymyalgia Rheumatica

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Developing Transcranial Neuromodulation Protocols for Learning and Decision-Making

NCT06561828

Recruiting

Background: People with substance use disorder (SUD) often have changes in brain function that can make it difficult to control drug-seeking behavior. These changes may heighten the urge to use drugs or lessen the desire to seek nondrug-related rewards. Researchers want to know how a technique called transcranial magnetic stimulation (TMS) may cause changes in brain activity that may help people with SUD. Objective: To test TMS in healthy volunteers. Eligibility: Healthy people aged 18 to 4... Read More

Gender:

ALL

Ages:

Between 18 years and 45 years

Trial Updated:

05/05/2025

Locations: National Institute on Drug Abuse, Baltimore, Maryland

Conditions: Normal Physiology

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A Trial of Felzartamab in Kidney Transplant Recipients With Late Antibody-Mediated Rejection (AMR)

NCT06685757

Recruiting

The main goal of this trial is to evaluate the efficacy of felzartamab compared to placebo in kidney transplant recipients diagnosed with late active or chronic active AMR.

Gender:

ALL

Ages:

Between 18 years and 75 years

Trial Updated:

05/05/2025

Locations: University of Southern California, Los Angeles, California +13 locations

Conditions: Antibody-mediated Rejection

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A Study to Assess the Relative Bioavailability of Risankizumab Following Subcutaneous Administration With On-Body Injector in Healthy Adult Participants

NCT06937619

Recruiting

This study will assess the pharmacokinetics and relative Bioavailability of risankizumab following subcutaneous (SC) administration with on-body Injector in Healthy Adult Participants.

Gender:

ALL

Ages:

Between 18 years and 60 years

Trial Updated:

05/05/2025

Locations: CenExel ACT- Anaheim Clinical Trials /ID# 274805, Anaheim, California +2 locations

Conditions: Healthy Volunteer

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Safety and Efficacy Study of Epcoritamab in Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia and Richter's Syndrome

NCT04623541

Recruiting

The study is a global, multi-center safety and efficacy trial of epcoritamab, an antibody also known as EPKINLY™ and GEN3013 (DuoBody®-CD3xCD20). Epcoritamab will be tested either in Relapsed/refractory (R/R) chronic lymphocytic leukemia (CLL) as: * Monotherapy, or * Combination therapy: * epcoritamab + venetoclax * epcoritamab + pirtobrutinib Treatment-naïve (TN) high risk (HR) (CLL): • epcoritamab + pirtobrutinib Combination therapy for Richter's Syndrome (RS): * epcoritamab + lenal... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/05/2025

Locations: O'Neal Comprehensive Cancer Center at University of Alabama at Birmingham, Birmingham, Alabama +76 locations

O'Neal Comprehensive Cancer Center at University of Alabama at Birmingham, Birmingham, Alabama

University of California Davis Medical Center Sacramento, California City, California

City of Hope National Medical Center, Duarte, California

Cedars-Sinai Medical Center, Los Angeles, California

David Geffen School of Medicine, Los Angeles, California

Stanford Cancer Center, Palo Alto, California

Mount Sinai Comprehensive Cancer Center, Miami Beach, Florida

Memorial Healthcare System, Pembroke Pines, Florida

Massachusetts General Hospital, Boston, Massachusetts

University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan

Henry Ford Medical Group, Detroit, Michigan

Hackensack Meridian Hospital, Hackensack, New Jersey

Northwell Health Cancer Institute, Lake Success, New York

Columbia University Herbert Irving Comprehensive Cancer Center, New York, New York

Memorial Sloan Kettering Cancer Center, New York, New York

James Cancer Hospital, Columbus, Ohio

University of Pennsylvania School of medicine, Philadelphia, Pennsylvania

The University of Texas Southwestern Medical Centre, Dallas, Texas

The University of Texas MD Anderson Cancer Center, Houston, Texas

Fred Hutchinson Cancer Research Center, Seattle, Washington

St. George Hospital, Kogarah, New South Wales

Barwon Health, Geelong, Victoria

Peter MacCallum Cancer Centre, Melbourne, Victoria

Alfred Health, Melbourne, Victoria

AZ Sint-Jan, Bruges, Not set

Universitair Ziekenhuis Gent, Gent, Not set

UZ Leuven, Leuven, Not set

Vseobecna Fakultni Nemocnice, Praha, Nové Město

Fakultni nemocnice Hradec Kralove, Hradec Králové, Nový Hradec Králové

Fakultni Nemocnice Ostrava, Ostrava, Poruba

Fakultni nemocnice Brno, Brno, Not set

Fakultni nemocnice Olomouc, Olomouc, Not set

Rigshospitalet, København, Hovedstaden

Aalborg University Hospital, Aalborg, Not set

Odense University Hospital, Odense, Not set

Roskilde Sygehus, Roskilde, Not set

Vejle Sygehus, Vejle, Not set

Århus University Hospital, Århus, Not set

CHU de Montpellier Hôpital Saint Eloi, Montpellier, Cedex 5

CHU Hôpital Haut-Lévêque Bordeaux, Pessac, Gironde

CHU Hôpital de Brabois Nancy, Vandœuvre-lès-Nancy, Meurthe Et Moselle

Hôpital Privé du Confluent, Nantes, Pays De La Loire

CHU Clermont Ferrand, Clermont Ferrand cedex, Puy De Dome

Hôpital Saint-Louis, Paris, Not set

Hôpital Universitaire Pitié-Salpêtrière, Paris, Not set

Universitaetsklinikum Schleswig-Holstein- Karl-Lennart-Krebscentrum, Kiel, Not set

Universitaetsklinikum Koeln, Koeln, Not set

Bnai Zion Medical Center, Haifa, Not set

Hadassah University Hospital - Ein Kerem, Jerusalem, Not set

Rabin Medical Center-Beilinson Campus, Petah Tikva, Not set

Chaim Sheba Medical Center, Ramat Gan, Not set

Tel Aviv Sourasky Medical Center, Tel Aviv-Yafo, Not set

IRCCS Istituto Romagnolo Per Lo Studio Dei Tumori Dino Amadori IRST, Meldola, Forli - Cesena

IRCCS Policlinico Universitario Agostino Gemelli, Roma, Lazio

AOU Policlinico Sant'Orsola Malpighi IRCCS, Bologna, Not set

Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (Presidio Spedali Civili), Brescia, Not set

Ospedale San Raffaele, Milano, Not set

Ospedale Maggiore di Novara, Novara, Not set

AOU Policlinico Umberto I, Roma, Not set

Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Not set

Maastricht University Medical Center, Maastricht, Limburg

Albert Schweitzer Ziekenhuis, Dordwijk, Dordrecht, South Holland

Amsterdam UMC, Amsterdam, Not set

Universitair Medisch Centrum Groningen, Groningen, Not set

Universitair Medisch Centrum Utrecht, Utrecht, Not set

ICO Badalona - Hospital Universitario Germans Trias Pujol, Badalona, Barcelona

AOC Arcispedale Saint'Anna, Coaña, Ferarra

Hospital Clinico Universitario de Valencia, Valencia, València

Hospital Clinic de Barcelona, Barcelona, Not set

Hospital de la Santa Creu i Sant Pau, Barcelona, Not set

Hospital Universitario Ramón y Cajal, Madrid, Not set

Hospital Universitario Fundacion Jiménez Díaz, Madrid, Not set

Hospital Universitario Virgen Macarena, Sevilla, Not set

Royal Cornwall Hospital, Truro, Cornwall

Nottingham University Hospitals City Campus, Nottingham, Nottinghamshire

St. James s University Hospital, Leeds, West Yorkshire

Barts Hospital, London, Not set

Conditions: Relapsed/Refractory Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Richter's Syndrome, Treatment-naïve High Risk Chronic Lymphocytic Leukemia

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A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer

NCT05365581

Recruiting

Claudin 18.2 protein, or CLDN18.2 is a protein found on cells in the digestive system. It is also found on some tumors. Researchers are looking at ways to attack CLDN18.2 to help control tumors. ASP2138 is thought to bind to CLDN18.2 and a protein on a type of immune cell called a T-cell. This "tells" the immune system to attack the tumor. ASP2138 is a potential treatment for people with stomach cancer, gastroesophageal junction cancer (GEJ cancer) or pancreatic cancer. GEJ is where the tube that carries food (esophagus) joins the stomach. Before ASP2138 is available as a treatment, the researchers need to understand how it is processed by and acts upon the body. In this study, ASP2138 will either be given by itself, or given together with standard treatments for gastric, GEJ and pancreatic cancer. Pembrolizumab and mFOLFOX6, and ramucirumab and paclitaxel are standard treatments for gastric and GEJ cancer. mFOLFIRINOX is a standard treatment for pancreatic cancer. This information will help find a suitable dose of ASP2138 given by itself and together with the standard cancer treatments and to check for potential medical problems from the treatments. The main aims of the study are: * To check the safety of ASP2138 and how well people can tolerate medical problems during the study. * To find a suitable dose of ASP2138 to be used later in the study. * These are done for ASP2138 given by itself and when given together with the standard cancer treatments. Adults 18 years or older with stomach cancer, GEJ cancer, or pancreatic cancer can take part. Their cancer is locally advanced unresectable or metastatic. Locally advanced means the cancer has spread to nearby tissue. Unresectable means the cancer cannot be removed by surgery. Metastatic means the cancer has spread to other parts of the body. There should also be the CLDN18.2 marker in a tumor sample. People cannot take part if they need to take medicines to suppress their immune system, have blockages or bleeding in their gut, have specific uncontrollable cancers, have specific infections, have a condition such as hemophagocytic lymphohistiocytosis (HLH) which is when the body over-reacts to a "trigger" such as infection, or have a specific heart condition ("New York Heart Association Class III or IV"). Phase 1: Lower to higher doses of ASP2138 * ASP2138 is either given through a vein (intravenous infusion) or just under the skin (subcutaneous injection). * Different small groups are given lower to higher doses of ASAP2138. * ASP2138 is either given by itself, or given with 1 of 3 standard treatments: * Pembrolizumab and mFOLFOX6 (first treatment for gastric GEJ cancer) * Ramacirumab and paclitaxel (Second treatment for gastric or GEJ cancer) * ASP2138 with mFOLFIRINOX (first treatment for pancreatic cancer) Phase 1b: doses of ASP2138 worked out from Phase 1 * ASP2138 is either given through a vein or just under the skin. This depends on the findings from Phase 1. * People with gastric cancer, GEJ cancer or pancreatic cancer are given doses of ASP2138, worked out from Phase 1. * This includes doses of ASP2138 given by itself and ASP2138 given with the standard cancer treatments. * The standard cancer treatments given depends on the type of cancer they have. End of treatment visit: This is 7 days after final dose of study treatment or if the study doctor decides to stop the person's treatment. People who have locally advanced unresectable pancreatic cancer will not receive ASP2138 by itself. Read Less

Gender:

ALL

Ages:

18 years and above

Trial Updated:

05/05/2025

Locations: University of California Irvine Medical Center, Orange, California +39 locations

University of California Irvine Medical Center, Orange, California

UCLA Dept of Medicine - Hematology/Oncology, Santa Monica, Santa Monica, California

Northwestern University, Chicago, Illinois

University of Kansas Cancer Center, Westwood, Kansas

Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey

NYU Langone Medical Center - NYU Medical Oncology Associates, New York, New York

Columbia University, New York, New York

Memorial Sloan Kettering Cancer Center, New York, New York

Duke Children's Hospital and Health Center, Durham, North Carolina

Wake Forest University Baptist Health, Winston-Salem, North Carolina

UT Southwestern Medical Center, Dallas, Texas

Virginia Mason Medical Center, Seattle, Washington

Froedtert Hospital and the Medical College of Wisconsin, Milwaukee, Wisconsin

Sun Yat-sen University Cancer Center, Guangzhou, Guangdong

Henan Cancer Hospital, Zhengzhou, Henan

Union Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei

Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, Shanghai

The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang

Site FR33005, Vaillant, Villejuif

Site FR33003, Lyon Cedex 08, Not set

Site FR33004, Marseille, Not set

Site FR33006, Poitiers, Not set

Site FR33001, Saint-Herblain, Not set

Site FR33002, Toulouse, Not set

Site IT39001, Milano, Not set

Site IT39004, Milan, Not set

Site IT39005, Rozzano, Not set

Site IT39003, Verona, Not set

Aichi Cancer Center, Nagoya, Aichi

National Cancer Center Hospital East, Kashiwa, Chiba

Kanagawa Cancer Center, Yokohama, Kanagawa

Kindai University Hospital, Osakasayama, Osaka

Osaka University Hospital, Suita, Osaka

National Cancer Center Hospital, Chuo-ku, Tokyo

The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Koto-ku, Tokyo

Site KR82004, Seongnam-si, Gyeonggi-do

Site KR82001, Guro-gu, Seoul

Site KR82002, Jongno-gu, Seoul

Site KR82003, Seocho-gu, Seoul

Site KR82005, Seodaemun-gu, Seoul

Conditions: Gastric Adenocarcinoma, Gastroesophageal Junction (GEJ) Adenocarcinoma, Pancreatic Adenocarcinoma

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ARTEMIS: Ravulizumab to Protect Patients With CKD From CSA-AKI and MAKE

NCT05746559

Recruiting

The primary objective of this study is to assess the efficacy of a single dose of ravulizumab IV compared with placebo in reducing the risk of the clinical consequences of AKI (MAKE) at 90 days in adult participants with CKD who undergo non-emergent cardiac surgery with CPB.

Gender:

ALL

Ages:

Between 18 years and 90 years

Trial Updated:

05/05/2025

Locations: Research Site, Tucson, Arizona +213 locations

Research Site, Tucson, Arizona

Research Site, Orange, California

Research Site, San Francisco, California

Research Site, Stanford, California

Research Site, Aurora, Colorado

Research Site, Washington, District of Columbia

Research Site, Gainesville, Florida

Research Site, Orlando, Florida

Research Site, Weston, Florida

Research Site, Atlanta, Georgia

Research Site, Chicago, Illinois

Research Site, Fort Wayne, Indiana

Research Site, Indianapolis, Indiana

Research Site, Louisville, Kentucky

Research Site, Boston, Massachusetts

Research Site, Springfield, Massachusetts

Research Site, Detroit, Michigan

Research Site, Kansas City, Missouri

Research Site, Saint Louis, Missouri

Research Site, Lincoln, Nebraska

Research Site, Haddon Heights, New Jersey

Research Site, Rochester, New York

Research Site, Valhalla, New York

Research Site, Durham, North Carolina

Research Site, Winston-Salem, North Carolina

Research Site, Fargo, North Dakota

Research Site, Cleveland, Ohio

Research Site, Columbus, Ohio

Research Site, Philadelphia, Pennsylvania

Research Site, Charleston, South Carolina

Research Site, Dallas, Texas

Research Site, Houston, Texas

Research Site, Plano, Texas

Research Site, San Antonio, Texas

Research Site, Salt Lake City, Utah

Research Site, Charlottesville, Virginia

Research Site, Richmond, Virginia

Research Site, Seattle, Washington

Research Site, Tacoma, Washington

Research Site, Wisconsin Rapids, Wisconsin

Research Site, Buenos Aires, Not set

Research Site, Caba, Not set

Research Site, Ciudad Autónoma de Bs. As., Not set

Research Site, Cordoba, Not set

Research Site, Corrientes, Not set

Research Site, Córdoba, Not set

Research Site, San Luis, Not set

Research Site, Santa Fé, Not set

Research Site, Adelaide, Not set

Research Site, Brisbane, Not set

Research Site, Canberra, Not set

Research Site, Heidelberg, Not set

Research Site, Monash, Not set

Research Site, Murdoch, Not set

Research Site, Southport, Not set

Research Site, Vienna, Not set

Research Site, Belo Horizonte, Not set

Research Site, Brasillia, Not set

Research Site, Campinas, Not set

Research Site, Fortaleza, Not set

Research Site, Porto Alegre, Not set

Research Site, Recife, Not set

Research Site, Ribeirão Preto, Not set

Research Site, Rio de Janeiro, Not set

Research Site, S.J. Do Rio Preto, Not set

Research Site, Salvador, Not set

Research Site, Sao Paulo, Not set

Research Site, São Paulo, Not set

Research Site, Edmonton, Alberta

Research Site, Winnipeg, Manitoba

Research Site, Saint John, New Brunswick

Research Site, Hamilton, Ontario

Research Site, Kingston, Ontario

Research Site, Toronto, Ontario

Research Site, Montreal, Quebec

Research Site, Montréal, Quebec

Research Site, Beijing, Not set

Research Site, Fuzhou, Not set

Research Site, Gaozhou, Not set

Research Site, Guangzhou, Not set

Research Site, Hangzhou, Not set

Research Site, Huai'an, Not set

Research Site, Ningbo, Not set

Research Site, Shanghai, Not set

Research Site, Shenzhen, Not set

Research Site, Tianjin, Not set

Research Site, Wuhan, Not set

Research Site, Xi'an, Not set

Research Site, Zhengzhou City, Not set

Research Site, Zhengzhou, Not set

Research Site, Zunyi, Not set

Research Site, Bordeaux Cedex, Not set

Research Site, Dijon Cedex, Not set

Research Site, Montpellier, Not set

Research Site, Toulouse Cedex 3, Not set

Research Site, Dresden, Not set

Research Site, Essen, Not set

Research Site, Frankfurt am Main, Not set

Research Site, Giessen, Not set

Research Site, Halle (Saale), Not set

Research Site, Heidelberg, Not set

Research Site, Jena, Not set

Research Site, Muenster, Not set

Research Site, München, Not set

Research Site, Stuttgart, Not set

Research Site, Trier, Not set

Research Site, Alexandroupolis, Not set

Research Site, Athens, Not set

Research Site, Thessaloniki, Not set

Research Site, Hong Kong, Not set

Research Site, Bangalore, Not set

Research Site, Delhi, Not set

Research Site, Gurgaon, Not set

Research Site, Hyderabad, Not set

Research Site, Mysuru, Not set

Research Site, Secunderabad, Not set

Research Site, Haifa, Not set

Research Site, Petah Tikva, Not set

Research Site, Ramat Gan, Not set

Research Site, Bari, Not set

Research Site, Firenze, Not set

Research Site, Milano, Not set

Research Site, Milan, Not set

Research Site, Napoli, Not set

Research Site, Bunkyo-ku, Not set

Research Site, Chuo-ku, Not set

Research Site, Kamakura-shi, Not set

Research Site, Kawasaki-shi, Not set

Research Site, Minato-ku, Not set

Research Site, Okayama-shi, Not set

Research Site, Sagamihara-shi, Not set

Research Site, Suginami, Not set

Research Site, Urayasu, Not set

Research Site, Anyang-si, Not set

Research Site, Bucheon-si, Not set

Research Site, Busan, Not set

Research Site, Daegu, Not set

Research Site, Seongnam-si, Not set

Research Site, Seoul, Not set

Research Site, Groningen, Not set

Research Site, Maastricht, Not set

Research Site, Rotterdam, Not set

Research Site, Białystok, Not set

Research Site, Bielsko-Biała, Not set

Research Site, Chrzanów, Not set

Research Site, Grudziądz, Not set

Research Site, Katowice, Not set

Research Site, Kraków, Not set

Research Site, Poznań, Not set

Research Site, Szczecin, Not set

Research Site, Tychy, Not set

Research Site, Warszawa, Not set

Research Site, Łódź, Not set

Research Site, Coimbra, Not set

Research Site, Lisboa, Not set

Research Site, A Coruna, Not set

Research Site, Barcelona, Not set

Research Site, Córdoba, Not set

Research Site, Madrid, Not set

Research Site, Majadahonda, Not set

Research Site, Navarra, Not set

Research Site, Santander, Not set

Research Site, Sevilla, Not set

Research Site, Valencia, Not set

Research Site, Valladolid, Not set

Research Site, Hualien City, Not set

Research Site, Kaohsiung, Not set

Research Site, New Taipei, Not set

Research Site, Taichung, Not set

Research Site, Tainan City, Not set

Research Site, Taipei City, Not set

Research Site, Taipei, Not set

Research Site, Ankara, Not set

Research Site, Antalya, Not set

Research Site, Istanbul, Not set

Research Site, Menemen/Izmir, Not set

Research Site, Odunpazarı, Not set

Research Site, Cambridge, Not set

Research Site, Clydebank, Not set

Research Site, Edinburgh, Not set

Research Site, London, Not set

Research Site, Newcastle upon Tyne, Not set

Conditions: Chronic Kidney Disease, CKD, Cardiac Disease, Cardiopulmonary Bypass

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Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)

NCT06122779

Recruiting

The purpose of this study is to evaluate the safety, tolerability, and exposure-response (E-R) of BMS-986435/MYK-224 in participants with symptomatic Heart Failure with Preserved Ejection Fraction (HFpEF).

Gender:

ALL

Ages:

Between 40 years and 90 years

Trial Updated:

05/05/2025

Locations: University of Alabama at Birmingham, Birmingham, Alabama +106 locations

University of Alabama at Birmingham, Birmingham, Alabama

Local Institution - 0096, Lakewood, Colorado

Local Institution - 0077, Jacksonville, Florida

Infinite Clinical Research, Miami, Florida

Local Institution - 0099, Miami, Florida

Local Institution - 0014, Atlanta, Georgia

Local Institution - 0048, Atlanta, Georgia

Bluhm Cardiovascular Institute of Northwestern, Chicago, Illinois

Chicago Medical Research, LLC, Hazel Crest, Illinois

Ascension Medical Group St. Vincent - Indianapolis Heart Care, Indianapolis, Indiana

Local Institution - 0045, Indianapolis, Indiana

St. Louis Heart and Vascular, Saint Louis, Missouri

Local Institution - 0043, Saint Louis, Missouri

Local Institution - 0070, Albany, New York

Local Institution - 0105, Brooklyn, New York

Weill Cornell Medicine, New York, New York

Local Institution - 0059, Rochester, New York

Local Institution - 0076, Rochester, New York

Local Institution - 0094, Rosedale, New York

Local Institution - 0095, Durham, North Carolina

Local Institution - 0058, Cincinnati, Ohio

Local Institution - 0041, Oklahoma City, Oklahoma

South Oklahoma Heart Research, Oklahoma City, Oklahoma

Local Institution - 0078, Abington, Pennsylvania

Tennessee Center for Clinical Trials, Tullahoma, Tennessee

Local Institution - 0104, Austin, Texas

University of Texas Southwestern Medical Center, Dallas, Texas

Angiocardiac Care of Texas - PA - PPDS, Houston, Texas

Local Institution - 0051, Houston, Texas

Local Institution - 0066, Falls Church, Virginia

Local Institution - 0060, Ciudad Autónoma de Buenos Aires, Buenos Aires

Local Institution - 0054, General San Martín, Buenos Aires

Local Institution - 0107, Zárate, Buenos Aires

Local Institution - 0090, Córdoba, Cordoba

Local Institution - 0053, Córdoba, Cordoba

Local Institution - 0073, Rosario, Santa FE

Local Institution - 0061, San Miguel De Tucumán, Tucuman

Local Institution - 0067, Ciudad Autonoma de Buenos Aires, Not set

Local Institution - 0068, Ciudad Autónoma de Buenos Aires, Not set

Local Institution - 0074, Córdoba, Not set

Local Institution - 0069, Salta, Not set

Local Institution - 0102, Santa Fe, Not set

Hamilton General Hospital, Hamilton, Ontario

Medicus MFC Inc., Toronto, Ontario

Local Institution - 0030, Toronto, Ontario

Local Institution - 0040, Toronto, Ontario

Local Institution - 0011, Montreal, Quebec

Local Institution - 0035, Trois-Rivieres, Quebec

Peking Union Medical College Hospital, Beijing, Beijing

Local Institution - 0087, Guangzhou, Guangdong

Local Institution - 0080, Luoyang, Henan

Local Institution - 0079, Changsha, Hunan

The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang

Local Institution - 0106, Rehovot, Not set

Local Institution - 0019, Napoli, Campania

Local Institution - 0023, Milano, Lombardia

Local Institution - 0033, Milano, Lombardia

IRCCS Policlinico San Donato, San Donato Milanese, Lombardia

Local Institution - 0050, San Donato Milanese, Lombardia

Local Institution - 0027, Foggia, Puglia

Local Institution - 0038, Foggia, Puglia

Local Institution - 0052, Massa, Toscana

Local Institution - 0009, Bergamo, Not set

Local Institution - 0017, Pisa, Not set

Local Institution - 0092, Himeji-Shi, Hyogo

Local Institution - 0100, Kanazawa, Ishikawa

Local Institution - 0091, Okayama-Shi, Okayama

Local Institution - 0093, Kishiwada, Osaka

Local Institution - 0103, Takatsuki-Shi, Osaka

Local Institution - 0088, Daegu, Daegu Gwang'yeogsi

Local Institution - 0084, Daejeon, Daejeon Gwang'yeogsi

Local Institution - 0083, Gwangju, Gwangju Gwang'yeogsi

Inha University Hospital, Jung-gu, Incheon Gwang'yeogsi

Local Institution - 0085, Seoul, Seoul Teugbyeolsi

Local Institution - 0055, Seoul, Seoul Teugbyeolsi

Local Institution - 0086, Busan, Not set

Local Institution - 0098, Seongnam-si, Not set

Local Institution - 0081, Seoul, Not set

Clinical Trials UMED Sp. z o.o., Lódz, Lódzkie

Local Institution - 0031, Bialystok, Podlaskie

Local Institution - 0044, Bialystok, Podlaskie

Local Institution - 0020, Lublin, Woj. Lubelskie

Local Institution - 0049, Lublin, Woj. Lubelskie

Local Institution - 0006, Krakow, Not set

Local Institution - 0024, Oswiecim, Not set

Local Institution - 0012, Hospitalet de Llobregat, Barcelona

Local Institution - 0025, Majadahonda, Madrid

Local Institution - 0047, Majadahonda, Madrid

Hospital Universitario Virgen de La Arrixaca, El Palmar, Murcia

Local Institution - 0039, El Palmar, Murcia

Local Institution - 0042, Malaga, Málaga

Local Institution - 0026, Madrid, Not set

Local Institution - 0034, Madrid, Not set

Local Institution - 0032, Malaga, Not set

Hospital Nuestra Señora de Valme, Sevilla, Not set

Local Institution - 0046, Sevilla, Not set

Local Institution - 0010, Valencia, Not set

Local Institution - 0063, Harrow, Greater London

Local Institution - 0071, North Shields, Northumberland

Local Institution - 0062, Oxford, Oxfordshire

Local Institution - 0072, Leeds, Yorkshire

Local Institution - 0057, Sheffield, Yorkshire

Local Institution - 0101, Bristol, Not set

Local Institution - 0097, Dundee, Not set

Local Institution - 0075, London, Not set

Local Institution - 0065, Stockton-On-Tees, Not set

Local Institution - 0064, Wolverhampton, Not set

Conditions: Heart Failure

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