The state of California currently has 14 active clinical trials seeking participants for Macular Edema research studies. These trials are conducted in various cities, including Los Angeles, San Francisco, San Diego and Sacramento.
Vamikibart in Participants With Uveitic Macular Edema
Recruiting
This study will assess the efficacy and safety of vamikibart in participants with uveitic macular edema.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/17/2024
Locations: Northern California Retina Vitreous Associates, Mountain View, California +5 locations
Conditions: Uveitic Macular Edema
A Study to Learn How Well a Higher Amount of Aflibercept Given as an Injection Into the Eye Works and How Safe it is in People With Reduced Vision Due to Swelling in the Macula, Central Part of the Retina Caused by a Blocked Vein in the Retina (Macula Edema Secondary to Retinal Vein Occlusion)
Recruiting
Researchers are looking for a better way to treat people who have macular edema secondary to retinal vein occlusion (RVO). In people with RVO, a blood vessel that carries blood away from the retina (vein) becomes blocked. The retina is the very back part of the eye. The blocked vein causes fluid and blood to leak into the retina and thereby causes a swelling of the macula (the center of the retina responsible for fine vision). This swelling is called macular edema. When a vein in the retina is... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/14/2024
Locations: Retina Consultants of Orange County, Fullerton, California +7 locations
Conditions: Macular Edema Secondary to Retinal Vein Occlusion
Treat & Extend Versus Fixed Dosing With Faricimab for Management of Diabetic Macular Edema: A Pragmatic, Multi-center, Open-label, Randomized, Controlled Trial
Recruiting
This study will assess a pragmatic, treat and extend regimen of faricimab against the standard of a fixed dosing regimen.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/14/2024
Locations: Retinal Consultants Medical Group Inc., Modesto, California +1 locations
Conditions: Diabetic Macular Edema
Evaluation of Tonabersat for DME
Recruiting
This randomized clinical trial will evaluate the effect of tonabersat compared with placebo on central subfield thickness (CST) in eyes with center-involved diabetic macular edema (CI-DME) and good visual acuity.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/04/2024
Locations: Retina Associates of Southern California, Huntington Beach, California +4 locations
Conditions: Diabetic Macular Edema
A Study to Investigate Faricimab Treatment Response in Treatment-Naive, Underrepresented Patients With Diabetic Macular Edema
Recruiting
This study is designed to investigate treatment response in treatment-naïve underrepresented patients with diabetic macular edema (DME) who are treated with faricimab. The study population will consist of participants ≥18 years of age who self-identify as Black/African American, Hispanic/Latino American, or Native American/Alaska Native/Native Hawaiian or other Pacific Islander; in addition, a cohort of Asian Indian participants will be enrolled in India.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/03/2024
Locations: Win Retina, Arcadia, California +5 locations
Conditions: Diabetic Macular Edema
A Real-World Study to Gain Clinical Insights Into Roche Ophthalmology Products
Recruiting
The VOYAGER study is a primary data collection, non-interventional, prospective, multinational, multicenter study. It is designed to collect real-world, long-term data to explore long-term effectiveness, safety, clinical insights, treatment patterns, and factors driving the treatment decisions among patients being treated with specified Roche ophthalmology products (Faricimab and Port Delivery System with Ranibizumab) in approved retinal indications (neovascular age-related macular degeneration... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/03/2024
Locations: Retina-Vitreous Associates Medical Group, Beverly Hills, California +2 locations
Conditions: Neovascular Age-related Macular Degeneration, Diabetic Macular Edema
Study to Assess the Efficacy & Safety of KHK4951 in Patients With Diabetic Macular Edema
Recruiting
The purpose of this study is to evaluate efficacy and safety of KHK4951 eye drops in patients with DME.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/31/2024
Locations: Win Retina, Arcadia, California +5 locations
Conditions: Diabetic Macular Edema (DME)
A Study to Investigate Vamikibart in Participants With Uveitic Macular Edema
Recruiting
This study will assess the efficacy and safety of vamikibart in participants with uveitic macular edema.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/29/2024
Locations: Jules Stein Eye Institute/ UCLA, Los Angeles, California +1 locations
Conditions: Uveitic Macular Edema
Assess the Efficacy and Safety of Repeat Intravitreal Injections of Foselutoclax (UBX1325) in Patients With DME (ASPIRE)
Recruiting
The goal of this clinical trial is to assess the efficacy and safety of multiple doses of foselutoclax (UBX1325) in patients with Diabetic Macular Edema. The main questions the study aims to answer are: Assess the efficacy of foselutoclax compared to aflibercept Assess the safety and tolerability of foselutoclax
Gender:
All
Ages:
18 years and above
Trial Updated:
05/03/2024
Locations: California Retina Consultants, Bakersfield, California +3 locations
Conditions: Diabetic Macular Edema, Retinal Disease, Macular Edema, Diabetes Mellitus, Diabetic Retinopathy, Retinal Degeneration, Retinal Diseases, Eye Diseases, Edema
A 2-part Study Consisting of Multiple Ascending Dose (MAD) Safety Study, and a Dose-finding Masked Study to Assess the Safety and Efficacy of Intravitreal (IVT) EYE103 in Patients With Diabetic Macular Edema (DME) or Neovascular Age-related Macular Degeneration (NVAMD)
Recruiting
EYE103-101 is a 2-part study assessing safety and preliminary efficacy of EYE103 in patients with diabetic macular edema (DME) given as monotherapy or neovascular macular degeneration (NVAMD) given in combination with anti-VEGF. In the first part, termed the multiple ascending dose (MAD) portion of study, the safety of EYE103 will be assessed at escalating doses. Approximately 12 participants will be entered in this part of the study. In the second part of the study, called the dose finding pa... Read More
Gender:
All
Ages:
50 years and above
Trial Updated:
12/05/2023
Locations: Bakersfield, CA, Bakersfield, California +4 locations
Conditions: Neovascular Age-related Macular Degeneration (NVAMD), Diabetic Macular Edema (DME)
Multicenter Study on the Efficacy and Safety of OCS-01 in Subjects With Uveitis Related and Post Surgical Macular Edema
Recruiting
The goal of the LEOPARD clinical trial is to investigate a new kind of steroid eye drops, OCS-01. Macular edema is a condition in which there is collection of fluid (edema) in the back of the eye (Macula) and it can lead to severe loss of vision. Among other causes, macular edema can happen because of a disease of the eye called Uveitis, and also after eye surgery. Treatment of macular edema remains a challenge as the condition may persist for several months and may lead to irreversible changes... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/20/2023
Locations: Retina Vitreous Associates Medical Group, Beverly Hills, California +2 locations
Conditions: Uveitis Related Cystoid Macular Edema, Cystoid Macular Edema, Postoperative
Assessing eFficacy and Safety of DEXTENZA 0.4 mg inseRt, Following Cataract Surgery
Recruiting
Assessing eFficacy and Safety of DEXTENZA 0.4 mg inseRt, Following Cataract Surgery
Gender:
All
Ages:
18 years and above
Trial Updated:
07/21/2023
Locations: Advanced Vision Care, Los Angeles, California
Conditions: Corneal Edema, Corneal Defect, Anterior Chamber Inflammation, Ocular Pain, Corneal Staining, Visual Outcome, CME - Cystoid Macular Edema