There are currently 23 active clinical trials seeking participants for Pulmonary Embolism research studies. The states with the highest number of trials for Pulmonary Embolism participants are Ontario, California, Florida and Pennsylvania.
Selective Pulmonary-artery Intervention to Reduce Acute Right-heart tEnsion-II
NCT06576427
Recruiting
This study is a prospective, single-arm, multicenter study to evaluate the safety and effectiveness of the Vertex Pulmonary Embolectomy System in participants presenting with clinical signs and symptoms of acute pulmonary embolism.
Gender:
ALL
Ages:
Between 18 years and 79 years
Trial Updated:
08/18/2025
Locations: Hartford Hospital, Hartford, Connecticut +18 locations
Conditions: Pulmonary Embolism
Register for Updates
The PEERLESS II Study
NCT06055920
Recruiting
This study is a prospective, multicenter, randomized controlled trial of the FlowTriever System plus anticoagulation compared to anticoagulation alone for intermediate-risk acute PE.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/14/2025
Locations: UAB Division of Cardiovascular Disease, Birmingham, Alabama +82 locations
Conditions: Pulmonary Embolism
Register for Updates
The PERSEVERE Study
NCT06588634
Recruiting
RCT of High-Risk Pulmonary Embolism Comparing FlowTriever System vs. Standard of Care
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/11/2025
Locations: Yale University, New Haven, Connecticut +18 locations
Conditions: Pulmonary Embolism, Pulmonary Thromboembolism
Register for Updates
A Study of Mobility Outcomes in Post-Pulmonary Embolic Disease
NCT06695247
Recruiting
The purpose of this study is to develop a unique structure and delivery of home-based exercise through multidisciplinary expertise of cardiovascular medicine specialists and cardiac physiologists using an Interactive Care Plan.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
08/04/2025
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Pulmonary Embolism
Register for Updates
Intervention to Improve Utilization of Extended Venous Thromboembolism Prophylaxis After Cancer Surgery
NCT06451003
Recruiting
While blood clots after major cancer surgery are common and harmful to patients, the medications to decrease blood clot risk are seldom used after patients leave the hospital despite the recommendation of multiple professional medical societies. The reason why these medications are seldom prescribed is not well understood. The main questions this study aims to answer are: * Does surgeon education paired with an electronic medical record based decision support tool improve the guideline concorda... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/28/2025
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Venous Thromboembolism, Pulmonary Embolism, Deep Vein Thrombosis, Cancer, Surgery
Register for Updates
Ultrasound-facilitated, Catheter-directed, Thrombolysis in Intermediate-high Risk Pulmonary Embolism
NCT04790370
Recruiting
There are many available treatments for pulmonary embolism (PE), but the best treatment for this condition is not known. The HI-PEITHO study will compare two treatment options that are both available on the market for the treatment of PE. Patients will be randomized 1:1 to receive either blood thinners (anticoagulation) or blood thinners (anticoagulation) in combination with a device called the EkoSonicTM Endovascular device to dissolve blood clots. Patients will be followed for 12 months after... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
07/21/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama +71 locations
Conditions: Pulmonary Embolism
Register for Updates
Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System
NCT04798261
Recruiting
The objective of this study is to evaluate real world long-term functional outcomes, safety and performance of the Indigo Aspiration System for the treatment of pulmonary embolism (PE).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/21/2025
Locations: Long Beach Medical Center, Long Beach, California +61 locations
Conditions: Pulmonary Embolism
Register for Updates
FUVID Study: Functional Characterization of Children With Chronic Venous Thromboembolic Disease
NCT04583878
Recruiting
This is a multi-center prospective cohort study of patients with first-episode deep venous thrombosis and pulmonary embolism.
Gender:
ALL
Ages:
Between 8 years and 21 years
Trial Updated:
07/08/2025
Locations: Arkansas Childrens Research Institute (ACRI), Little Rock, Arkansas +13 locations
Conditions: Deep Venous Thrombosis, Pulmonary Embolism
Register for Updates
CLEANer Aspiration for Pulmonary Embolism
NCT06189313
Recruiting
To evaluate the safety and efficacy of the Cleaner™ Pro Thrombectomy System for aspiration thrombectomy in patients with acute pulmonary embolism (PE).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/02/2025
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado +10 locations
Conditions: Pulmonary Embolism, Acute Pulmonary Embolism, Cardiovascular Diseases, Venous Thromboembolism
Register for Updates
Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy
NCT05591118
Recruiting
PE-TRACT is an open-label, assessor-blinded, randomized trial, aiming to compare catheter-directed therapy (CDT) and anticoagulation (CDT group) with anticoagulation alone (No-CDT) in 500 patients with submassive PE, proximal pulmonary artery thrombus and right ventricular dilation.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/18/2025
Locations: The University of Alabama At Birmingham, Birmingham, Alabama +39 locations
Conditions: Pulmonary Embolism
Register for Updates
Supplemental Oxygen in Pulmonary Embolism (SO-PE)
NCT05891886
Recruiting
A study of how supplemental oxygen helps patients with acute pulmonary embolism (PE). Hypothesis: Oxygen affects right ventricular dysfunction (RVD) in patients with acute pulmonary embolism (PE) primarily by relieving hypoxic pulmonary vasoconstriction and reducing pulmonary pressure (PA) pressure, and that this process is metabolically driven.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/12/2025
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Pulmonary Embolism, Venous Thromboembolism, Metabolomics, Oxygen Inhalation Therapy
Register for Updates
Treating Pulmonary Embolism With Laguna Thrombectomy System (TRUST)
NCT06041594
Recruiting
This is a prospective, multi-center, pivotal study to demonstrate the safety and effectiveness of the Laguna Thrombectomy System for the treatment of pulmonary embolism. The Laguna Thrombectomy System is an investigational device which consists of the Laguna Clot Retriever™ System and the Malibu Aspiration Catheter™ System. These devices are manufactured by Innova Vascular, Inc.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
04/30/2025
Locations: University of California Irvine, Irvine, California +13 locations
Conditions: Pulmonary Embolism
Register for Updates