There are currently 21 active clinical trials seeking participants for Pulmonary Embolism research studies. The states with the highest number of trials for Pulmonary Embolism participants are Ontario, California, Florida and Pennsylvania.
A Study Comparing Abelacimab to Dalteparin in the Treatment of Gastrointestinal/Genitourinary Cancer and Associated VTE
Recruiting
This is a Phase 3, multicenter, open-label, blinded endpoint study to evaluate the effect of abelacimab relative to dalteparin on venous thromboembolism (VTE) recurrence and bleeding in patients with gastrointestinal (GI)/genitourinary (GU) cancer associated VTE (Magnolia)
Gender:
All
Ages:
18 years and above
Trial Updated:
06/20/2024
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado +182 locations
Conditions: Venous Thromboembolism, Deep Venous Thrombosis, Pulmonary Embolism
A Study Comparing Abelacimab to Apixaban in the Treatment of Cancer-associated VTE
Recruiting
This is a Phase 3,multicenter, randomized, open-label, blinded endpoint evaluation study comparing the effect of abelacimab relative to apixaban on venous thromboembolism (VTE) recurrence and bleeding in patients with cancer associated VTE (ASTER)
Gender:
All
Ages:
18 years and above
Trial Updated:
06/20/2024
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado +215 locations
Conditions: Venous Thromboembolism, Deep Venous Thrombosis, Pulmonary Embolism
Ultrasound-facilitated, Catheter-directed, Thrombolysis in Intermediate-high Risk Pulmonary Embolism
Recruiting
There are many available treatments for pulmonary embolism (PE), but the best treatment for this condition is not known. The HI-PEITHO study will compare two treatment options that are both available on the market for the treatment of PE. Patients will be randomized 1:1 to receive either blood thinners (anticoagulation) or blood thinners (anticoagulation) in combination with a device called the EkoSonicTM Endovascular device to dissolve blood clots. Patients will be followed for 12 months after... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
06/14/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama +71 locations
Conditions: Pulmonary Embolism
Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy
Recruiting
PE-TRACT is an open-label, assessor-blinded, randomized trial, aiming to compare catheter-directed therapy (CDT) and anticoagulation (CDT group) with anticoagulation alone (No-CDT) in 500 patients with submassive PE, proximal pulmonary artery thrombus and right ventricular dilation.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/29/2024
Locations: The University of Alabama At Birmingham, Birmingham, Alabama +39 locations
Conditions: Pulmonary Embolism
The PEERLESS II Study
Recruiting
This study is a prospective, multicenter, randomized controlled trial of the FlowTriever System plus anticoagulation compared to anticoagulation alone for intermediate-risk acute PE.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/21/2024
Locations: UAB Division of Cardiovascular Disease, Birmingham, Alabama +85 locations
Conditions: Pulmonary Embolism
Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence
Recruiting
Socioeconomically disadvantaged populations with multiple chronic conditions have high rates of nonadherence to essential chronic disease medications after hospital discharge. Medication nonadherence after hospital discharge is significantly associated with increased mortality and higher rates of readmissions and costs among these patients. Major patient-reported barriers to essential medication use after hospital discharge among low-income individuals are related to social determinants of healt... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/23/2024
Locations: University of Tennessee Medical Center, Knoxville, Tennessee +1 locations
Conditions: Diabetes, Hypertension, High Cholesterol/Hyperlipidemia, Coronary Artery Disease, Congestive Heart Failure, Chronic Lung Disease, Chronic Kidney Diseases, Arrythmia, Stroke, Depression, Anxiety, Pulmonary Embolism, Heart Attack
Aventus Thrombectomy System Pulmonary Embolism Clinical Study
Recruiting
Evaluate the safety and efficacy of the Aventus Thrombectomy System for aspiration thrombectomy in subjects with acute pulmonary embolism.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
04/03/2024
Locations: Honor Health, Scottsdale, Arizona +15 locations
Conditions: Pulmonary Embolism, Embolism, Embolism and Thrombosis, Vascular Diseases, Cardiovascular Diseases, Lung Diseases, Respiratory Tract Diseases
FUVID Study: Functional Characterization of Children With Chronic Venous Thromboembolic Disease
Recruiting
This is a multi-center prospective cohort study of patients with first-episode deep venous thrombosis and pulmonary embolism.
Gender:
All
Ages:
Between 8 years and 21 years
Trial Updated:
04/01/2024
Locations: Arkansas Children's Research Institute (ACRI), Little Rock, Arkansas +13 locations
Conditions: Deep Venous Thrombosis, Pulmonary Embolism
Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System
Recruiting
The objective of this study is to evaluate real world long-term functional outcomes, safety and performance of the Indigo Aspiration System for the treatment of pulmonary embolism (PE).
Gender:
All
Ages:
18 years and above
Trial Updated:
03/28/2024
Locations: Long Beach Medical Center, Long Beach, California +46 locations
Conditions: Pulmonary Embolism
Quantitative 3-Dimensional Chest CT Vascular Reconstruction Before and After Anticoagulation for Pulmonary Embolism
Recruiting
Design: U.S.-based, single-center, proof-of-concept study Brief Description: A standard clinical contrast-enhanced chest CT scan performed 48 hours after clinically-indicated standard anticoagulation will be compared with a standard clinically-indicated baseline contrast-enhanced chest CT scan using a previously-studied and previously-validated 3-dimensional reconstruction technique to assess changes in the pulmonary vasculature in patients with acute pulmonary embolism (PE). This previously-st... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/03/2024
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Pulmonary Embolism
COVID-19 Registry to Assess Frequency, Risk Factors, Management, and Outcomes of Arterial and Venous Thromboembolic Complications
Recruiting
Novel coronavirus 2019 (COVID-19) has emerged as a major international public health concern. While much of the morbidity and mortality associated with COVID-19 has been attributed to acute respiratory distress syndrome (ARDS) or end-organ failure, emerging data suggest that disorders of coagulation, in particular hypercoagulability and venous thromboembolism (VTE), may represent an additional major, and possibly preventable, complication (Wu C, et al. JAMA Intern Med. 2020 Mar 13. [Epub ahead o... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/03/2024
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Covid19, Thrombosis Embolism, DVT, Pulmonary Embolism, Myocardial Infarction, Stroke
Home Rehabilitation After Acute Pulmonary Embolism
Recruiting
The purpose of this study is to evaluate whether a home rehabilitation program after hospitalization for acute pulmonary embolism (PE) improves clinical outcomes at 3 months compared to usual care. Daily physical activity tasks that incorporate heart rate monitoring will be sent through email or text. This information could help improve the management of acute PE.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/07/2024
Locations: University of Rochester Medical Center, Rochester, New York
Conditions: Pulmonary Embolism