There are currently 24 active clinical trials seeking participants for Vascular Diseases research studies. The states with the highest number of trials for Autism participants are California, Florida, New York and Heilongjiang.
A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients
NCT03626688
Recruiting
Study ROR-PH-301, ADVANCE OUTCOMES, is designed to assess the efficacy and safety of ralinepag when added to pulmonary arterial hypertension (PAH) standard of care or PAH-specific background therapy in subjects with World Health Organization (WHO) Group 1 PAH.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/17/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama +212 locations
Conditions: PAH, Pulmonary Hypertension, Pulmonary Arterial Hypertension, Hypertension, Connective Tissue Diseases, Familial Primary Pulmonary Hypertension, Vascular Diseases, Cardiovascular Diseases, Hypertension, Pulmonary, Lung Diseases, Respiratory Tract Disease
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Natural History of Stroke: Cause and Development
NCT00009243
Recruiting
The purpose of this study is to learn more about stroke and obtain information that may serve as the basis for future investigations. It will 1) establish a registry of patients with cerebrovascular disease (stroke); 2) characterize the natural history of acute stroke and transient ischemic attacks (TIA)-an interruption of blood flow to the brain that causes stroke symptoms for a short period of time); and 3) evaluate the data to generate ideas for future studies. Patients 18 years of age or ol... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/16/2024
Locations: Medstar Washington Hospital Center, Washington, District of Columbia +2 locations
Conditions: Brain Disease, Ischemic Attack, Transient, Cerebrovascular Accident, Cerebrovascular Disorder, Vascular Diseases
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Improving Blood Pressure Control in Stroke Patients by Increasing Access to a Home Blood Pressure Monitor
NCT05730465
Recruiting
The goal of this clinical trial is to learn whether providing teaching with a low-cost device can help to improve blood pressure, health outcomes, patient self-efficacy without exacerbating inequity between advantaged and disadvantaged patients. The main question[s] it aims to answer are: Does providing a free home blood pressure cuff improve control of hypertension? Does providing a free home blood pressure cuff have a greater impact on control of hypertension in disadvantaged populations? Do... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/16/2024
Locations: Stanford University Hospital, Palo Alto, California
Conditions: Hypertension, Stroke, TIA, Vascular Diseases
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SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN
NCT05198674
Recruiting
The purpose of this single-arm interventional study is to evaluate the long-term safety, efficacy, and durability of the Symplicity Spyral system in subjects treated with renal denervation. Additionally, long-term follow-up data will also be collected from eligible subjects previously treated in the SPYRAL PIVOTAL-SPYRAL HTN-OFF MED and SPYRAL HTN-ON MED studies.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/11/2024
Locations: University of Alabama at Birmingham (UAB) Hospital, Birmingham, Alabama +79 locations
Conditions: Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus
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SYMPHONY-PE Study for Treatment of Pulmonary Embolism
NCT06062329
Recruiting
Evaluation of the Safety and Efficacy of the Symphony Thrombectomy System in the Treatment of Pulmonary Embolism
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
04/11/2024
Locations: Huntsville Hospital, Huntsville, Alabama +4 locations
Conditions: Acute Pulmonary Embolism, Thromboembolism, Emboli, Pulmonary, Thrombosis, Thrombus; Embolism, Embolism, Cardiovascular Diseases, Vascular Diseases
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Nicotinamide Riboside Supplementation for Treating Arterial Stiffness and Elevated Systolic Blood Pressure in Patients With Moderate to Severe CKD
NCT04040959
Recruiting
Risk of cardiovascular diseases (CVD) is significantly elevated in patients with chronic kidney disease (CKD); however, this increased risk is only partially explained by traditional CV risk factors. Arterial dysfunction is an important nontraditional CV risk factor gaining increased recognition in the field of nephrology. This process is best represented, both physiologically and pathophysiologically, by increases in the gold standard measure of arterial stiffening, carotid to femoral artery pu... Read More
Gender:
All
Ages:
Between 35 years and 80 years
Trial Updated:
04/09/2024
Locations: UColorado, Aurora, Colorado
Conditions: Vascular Diseases, Kidney Disease, Blood Pressure, Oxidative Stress
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Gene First Approach to Connective Tissue Disease
NCT04664478
Recruiting
Background: Elastic fibers affect parts of the body that stretch repetitively, such as the skin, blood vessels, and lungs. Researchers want to use medical and research tests in patients with already identified changes in a set of connective tissue genes to better understand diseases related to elastic fibers. Objective: To learn more about the impact of underlying changes in a set of connective tissue genes on people s overall health. Eligibility: People ages 2-100 who have had a gene test... Read More
Gender:
All
Ages:
Between 2 years and 100 years
Trial Updated:
04/06/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Abnormal Elastogenesis, Vascular Diseases, Connective Tissue Diseases
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Aventus Thrombectomy System Pulmonary Embolism Clinical Study
NCT05907564
Recruiting
Evaluate the safety and efficacy of the Aventus Thrombectomy System for aspiration thrombectomy in subjects with acute pulmonary embolism.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
04/03/2024
Locations: Honor Health, Scottsdale, Arizona +15 locations
Conditions: Pulmonary Embolism, Embolism, Embolism and Thrombosis, Vascular Diseases, Cardiovascular Diseases, Lung Diseases, Respiratory Tract Diseases
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Smartphone Twelve-Lead ECG Utility In ST-Elevation Myocardial Infarction II
NCT06271577
Recruiting
AliveCor (www.alivecor.com) has developed several electrocardiogram (ECG) devices that interface with iOS and Android smartphones and tablets via various Kardia apps. The current Kardia family of devices can measure single lead and six limb-lead ECGs, depending on the device. KardiaMobile, KardiaMobile 6L, and KardiaMobile Card have FDA clearance for ECG rhythm recording. A modified single-lead Kardia smartphone 12-lead ECG was previously validated in the multicenter ST LEUIS study for the diagn... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/18/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Myocardial Infarction, Ischemia, Myocardial Ischemia, Heart Diseases, Cardiovascular Diseases, Vascular Diseases, Heart Attack, Heart Failure
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Optimal Blood Pressure Treatment Thresholds Postpartum
NCT06069102
Recruiting
The objective of this research project is to conduct a single-site pilot trial within our institution's clinical remote blood pressures (BP) management program to assess the feasibility and effect of tight blood pressure control versus usual care in the immediate postpartum period after a hypertensive disorder of pregnancy (HDP). The investigators' central hypothesis is that tight blood pressure control will be feasible and acceptable to postpartum individuals and will result in lower BP at six... Read More
Gender:
Female
Ages:
Between 18 years and 55 years
Trial Updated:
02/28/2024
Locations: University of Pittsburgh Magee-Womens Hospital, Pittsburgh, Pennsylvania
Conditions: Hypertensive Disorder of Pregnancy, Pre-Eclampsia, Hypertension, Eclampsia, Gestational Hypertension, Cardiovascular Diseases, Toxemia, Pregnancy Complications, Vascular Diseases, Hypertension, Pregnancy Induced, Hypertension;Pre-Eclamptic
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Efficacy and Mechanisms of Dapagliflozin in Promoting Kidney Function and Cardiovascular Health in Kidney Transplant Recipients
NCT06140537
Recruiting
Long-term allograft function in kidney transplant recipients (KTRs) remain suboptimal, and graft failure causes significant morbidity and mortality, with cardiovascular disease being the leading cause of death in KTRs and the most common cause of death with a functioning graft. Sodium-glucose cotransporter 2 (SGLT2) inhibitors safely lower cardiovascular and kidney disease risk in the non-transplant population, yet data in KTRs are lacking. This clinical trial seeks to establish the efficacy and... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
02/15/2024
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Kidney Transplant; Complications, Vascular Diseases, Diabetes
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Effects of Blueberries in Older Adults
NCT05358210
Recruiting
This randomized, parallel-design trial will evaluate specific clinical and physiological effects of whole blueberries in adults 70 years of age or older.
Gender:
All
Ages:
Between 70 years and 100 years
Trial Updated:
01/31/2024
Locations: Center Communities of Brookline (CCB), Brookline, Massachusetts +1 locations
Conditions: Blood Pressure, Orthostatic Hypotension, Vascular Diseases
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