There are currently 24 active clinical trials seeking participants for Vascular Diseases research studies. The states with the highest number of trials for Autism participants are California, Florida, New York and Heilongjiang.
Smartphone Twelve-Lead ECG Utility In ST-Elevation Myocardial Infarction II
Recruiting
AliveCor (www.alivecor.com) has developed several electrocardiogram (ECG) devices that interface with iOS and Android smartphones and tablets via various Kardia apps. The current Kardia family of devices can measure single lead and six limb-lead ECGs, depending on the device. KardiaMobile, KardiaMobile 6L, and KardiaMobile Card have FDA clearance for ECG rhythm recording. A modified single-lead Kardia smartphone 12-lead ECG was previously validated in the multicenter ST LEUIS study for the diagn... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/18/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Myocardial Infarction, Ischemia, Myocardial Ischemia, Heart Diseases, Cardiovascular Diseases, Vascular Diseases, Heart Attack, Heart Failure
Natural History of Stroke: Cause and Development
Recruiting
The purpose of this study is to learn more about stroke and obtain information that may serve as the basis for future investigations. It will 1) establish a registry of patients with cerebrovascular disease (stroke); 2) characterize the natural history of acute stroke and transient ischemic attacks (TIA) an interruption of blood flow to the brain that causes stroke symptoms for a short period of time); and 3) evaluate the data to generate ideas for future studies. Patients 18 years of age or ol... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/14/2024
Locations: Medstar Washington Hospital Center, Washington, District of Columbia +2 locations
Conditions: Brain Disease, Ischemic Attack, Transient, Cerebrovascular Accident, Cerebrovascular Disorder, Vascular Diseases
A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients
Recruiting
Study ROR-PH-301, ADVANCE OUTCOMES, is designed to assess the efficacy and safety of ralinepag when added to pulmonary arterial hypertension (PAH) standard of care or PAH-specific background therapy in subjects with World Health Organization (WHO) Group 1 PAH.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/11/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama +211 locations
Conditions: PAH, Pulmonary Hypertension, Pulmonary Arterial Hypertension, Hypertension, Connective Tissue Diseases, Familial Primary Pulmonary Hypertension, Vascular Diseases, Cardiovascular Diseases, Hypertension, Pulmonary, Lung Diseases, Respiratory Tract Disease
SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN
Recruiting
The purpose of this single-arm interventional study is to evaluate the long-term safety, efficacy, and durability of the Symplicity Spyral system in subjects treated with renal denervation. Additionally, long-term follow-up data will also be collected from eligible subjects previously treated in the SPYRAL PIVOTAL-SPYRAL HTN-OFF MED and SPYRAL HTN-ON MED studies.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/08/2024
Locations: University of Alabama at Birmingham (UAB) Hospital, Birmingham, Alabama +78 locations
Conditions: Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus
Optimal Blood Pressure Treatment Thresholds Postpartum
Recruiting
The objective of this research project is to conduct a single-site pilot trial within our institution's clinical remote blood pressures (BP) management program to assess the feasibility and effect of tight blood pressure control versus usual care in the immediate postpartum period after a hypertensive disorder of pregnancy (HDP). The investigators' central hypothesis is that tight blood pressure control will be feasible and acceptable to postpartum individuals and will result in lower BP at six... Read More
Gender:
Female
Ages:
Between 18 years and 55 years
Trial Updated:
02/28/2024
Locations: University of Pittsburgh Magee-Womens Hospital, Pittsburgh, Pennsylvania
Conditions: Hypertensive Disorder of Pregnancy, Pre-Eclampsia, Hypertension, Eclampsia, Gestational Hypertension, Cardiovascular Diseases, Toxemia, Pregnancy Complications, Vascular Diseases, Hypertension, Pregnancy Induced, Hypertension;Pre-Eclamptic
Efficacy and Mechanisms of Dapagliflozin in Promoting Kidney Function and Cardiovascular Health in Kidney Transplant Recipients
Recruiting
Long-term allograft function in kidney transplant recipients (KTRs) remain suboptimal, and graft failure causes significant morbidity and mortality, with cardiovascular disease being the leading cause of death in KTRs and the most common cause of death with a functioning graft. Sodium-glucose cotransporter 2 (SGLT2) inhibitors safely lower cardiovascular and kidney disease risk in the non-transplant population, yet data in KTRs are lacking. This clinical trial seeks to establish the efficacy and... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
02/15/2024
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Kidney Transplant; Complications, Vascular Diseases, Diabetes
Effects of Blueberries in Older Adults
Recruiting
This randomized, parallel-design trial will evaluate specific clinical and physiological effects of whole blueberries in adults 70 years of age or older.
Gender:
All
Ages:
Between 70 years and 100 years
Trial Updated:
01/31/2024
Locations: Center Communities of Brookline (CCB), Brookline, Massachusetts +1 locations
Conditions: Blood Pressure, Orthostatic Hypotension, Vascular Diseases
Mitochondria Oxidative Stress and Vascular Health Study
Recruiting
Cardiovascular diseases (CVDs) are the number one cause of death in America and most of the post-industrial world. Hypertension is a leading risk factor for CVDs including stroke, myocardial infarction, and heart failure. Black Americans suffer from the highest rates of hypertension of any racial/ethnic group in America, among the highest in the world. There are also well-documented racial disparities in vascular dysfunction (e.g., endothelial dysfunction, arterial stiffening). Thus, racial disp... Read More
Gender:
All
Ages:
Between 45 years and 75 years
Trial Updated:
01/29/2024
Locations: Auburn University, Auburn, Alabama
Conditions: Cardiovascular Diseases, Hypertension, Racism, Vascular Diseases
SYMPHONY-PE Study for Treatment of Pulmonary Embolism
Recruiting
Evaluation of the Safety and Efficacy of the Symphony Thrombectomy System in the Treatment of Pulmonary Embolism
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
01/22/2024
Locations: Huntsville Hospital, Huntsville, Alabama +1 locations
Conditions: Acute Pulmonary Embolism, Thromboembolism, Emboli, Pulmonary, Thrombosis, Thrombus; Embolism, Embolism, Cardiovascular Diseases, Vascular Diseases
Aventus Thrombectomy System Pulmonary Embolism Clinical Study
Recruiting
Evaluate the safety and efficacy of the Aventus Thrombectomy System for aspiration thrombectomy in subjects with acute pulmonary embolism.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
01/16/2024
Locations: MemorialCare, Long Beach, California +5 locations
Conditions: Pulmonary Embolism, Embolism, Embolism and Thrombosis, Vascular Diseases, Cardiovascular Diseases, Lung Diseases, Respiratory Tract Diseases
Gene First Approach to Connective Tissue Disease
Recruiting
Background: Elastic fibers affect parts of the body that stretch repetitively, such as the skin, blood vessels, and lungs. Researchers want to use medical and research tests in patients with already identified changes in a set of connective tissue genes to better understand diseases related to elastic fibers. Objective: To learn more about the impact of underlying changes in a set of connective tissue genes on people s overall health. Eligibility: People ages 2-100 who have had a gene test... Read More
Gender:
All
Ages:
Between 2 years and 100 years
Trial Updated:
11/28/2023
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Abnormal Elastogenesis, Vascular Diseases, Connective Tissue Diseases
Vialize Use for the Reduction of Vascular Groin Incisional Dehiscence and Infection
Recruiting
Groin incisions in vascular surgery have complications in up to 30% of cases at 30 days, resulting in reductions in patient quality of life and increased costs. Prior attempts at reducing this complication rate have been largely unsuccessful. The purpose of this study is to determine the feasibility of routine Vialize use for vascular surgeries involving a groin incision and to determine the rates of surgical site infection/dehiscence in such patients receiving subcutaneous Vialize.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/23/2023
Locations: UF Health Heart & Vascular Hospital, Gainesville, Florida
Conditions: Vascular Diseases