The city of Los Angeles, California, currently has 35 active clinical trials seeking participants for Pain research studies.
Analgesic Efficacy of Anterior Femoral, Genicular and Adductor Canal Nerve Block
Recruiting
Recently, more distal approach to femoral nerve branches (saphenous) in the adductor canal in the medial compartment of the thigh have shown to provide comparable anesthesia and analgesia without quadriceps muscle weakness than traditional femoral nerve blocks (FNB) after total knee arthroplasty (TKA). Adductor canal block (ACB) has the unique advantage of providing localized analgesia to the peripatellar and intra-articular aspects of the knee joint without reducing the patient's ability to per... Read More
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
08/28/2023
Locations: Cedars Sinai Medical Center, Los Angeles, California
Conditions: Pain, Postoperative
Assessing eFficacy and Safety of DEXTENZA 0.4 mg inseRt, Following Cataract Surgery
Recruiting
Assessing eFficacy and Safety of DEXTENZA 0.4 mg inseRt, Following Cataract Surgery
Gender:
All
Ages:
18 years and above
Trial Updated:
07/21/2023
Locations: Advanced Vision Care, Los Angeles, California
Conditions: Corneal Edema, Corneal Defect, Anterior Chamber Inflammation, Ocular Pain, Corneal Staining, Visual Outcome, CME - Cystoid Macular Edema
Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes
Recruiting
Patients with digestive tract malignancy often experience severe and unremitting abdominal pain that negatively affects physical, emotional, and social function, as well as health related quality of life (HRQOL). Therapeutic virtual reality (VR) has emerged as a promising and evidence-based treatment modality for cancer pain. Users of VR wear a pair of goggles with a close-proximity screen in front of the eyes that creates a sensation of being transported into lifelike, three-dimensional worlds.... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
06/06/2023
Locations: Cedars-Sinai Medical Center, Los Angeles, California
Conditions: Cancer Pain, Visceral Pain, Gastrointestinal Neoplasms, Cancer of Gastrointestinal Tract, Small Intestine Cancer, Pancreas Cancer, Liver Cancer, Colon Cancer, Biliary Tract Cancer, Stomach Cancer, Rectum Cancer, Peritoneal Cancer, Gastrointestinal Cancer Metastatic, Gastrointestinal Cancers - Anus, Gastrointestinal Cancers - Stomach, Gastrointestinal Cancers - Colorectal, Gastrointestinal Cancers - Small Intestine, Small Intestine Cancer Stage III, Small Intestine Cancer Stage IV, Small Intestine Cancer, Recurrent, Pancreas Cancer, Stage III, Pancreas Cancer, Stage IV, Pancreas Cancer, Metastatic, Pancreas Cancer, Recurrent, Liver Cancer Stage IIIa, Liver Cancer Stage IIIb, Liver Cancer Stage IIIc, Liver Cancer Stage IV, Colon Cancer Stage III, Colon Cancer Stage IV, Stomach Cancer Stage III, Stomach Cancer Stage IV, Stomach Cancer Recurrent, Rectum Cancer, Recurrent, Gastrointestinal Cancers - Liver, Anal Cancer, Anal Cancer Stage III, Anal Cancer Stage IV, Anal Cancer Recurrent, Anal Cancer Metastatic, Anal Cancer, Stage IIIA, Anal Cancer, Stage IIIB, Appendix Cancer, Ampullary Cancer, Bile Duct Cancer, Bile Duct Cancer Stage III, Bile Duct Cancer Stage IV, Bile Duct Cancer Stage IVA, Bile Duct Cancer Stage IVB, Bile Duct Cancer Recurrent, Carcinoid Tumor, Carcinoid Tumor of Pancreas, Carcinoid Tumor of Large Intestine, Carcinoid Tumor of GI System, Carcinoid Tumor of Colon, Carcinoid Tumor of Liver, Carcinoid Tumor of Cecum, Carcinoid Tumor of Ileum, Carcinoid Tumor of Rectum, Carcinoid Tumor of the Small Bowel, Carcinoid Tumor of the Stomach, Large Intestine Cancer, Esophagus Cancer, Esophagus Cancer, Stage III, Esophagus Cancer, Stage IV, Esophagus Cancer, Recurrent, Gallbladder Cancer, Gallbladder Cancer Stage III, Gallbladder Cancer Stage IV, Gastric (Stomach) Cancer, Neuroendocrine Tumor, Peritoneum Cancer, Rectal Cancer, Esophagus Cancer, Stage I, Esophagus Cancer, Stage II, Gallbladder Cancer Stage I, Gallbladder Cancer Stage II, Bile Duct Cancer Stage I, Bile Duct Cancer Stage II
DBS of the SCC for the Treatment of Medically Refractory CLBP
Recruiting
The purpose of this study is to evaluate the feasibility and preliminary efficacy of deep brain stimulation of the subgenual cingulate cortex for the treatment of chronic medically-refractory low back pain using a randomized double-blind crossover design.
Gender:
All
Ages:
Between 40 years and 75 years
Trial Updated:
04/22/2023
Locations: University of California Los Angeles, Los Angeles, California
Conditions: Chronic Low-back Pain
Assessment of Urinary Polymerase Chain Reaction (PCR) and Next Generation Sequencing (NGS) Technology in the Evaluation and Management of Females With Chronic Bladder Pain and Cystitis-like Symptoms
Recruiting
Real-world clinical practice multicenter study to determine the clinical implications of employing PCR/NGS technology to identify and treat potential urinary pathogens in female participants identified with bladder pain and/or cystitis-like symptoms.
Gender:
Female
Ages:
Between 18 years and 80 years
Trial Updated:
03/13/2023
Locations: UCLA Center for Women's Pelvic Health, Los Angeles, California
Conditions: Interstitial Cystitis, Bladder Pain Syndrome
AnalgeSiC and appEtite-stimulating Effects of caNnabigerol and THC (ASCENT)
Recruiting
This study will assess the analgesic, appetite-stimulating, and subjective effects of cannabigerol (CBG) alone and in combination with THC.
Gender:
All
Ages:
Between 21 years and 55 years
Trial Updated:
03/13/2023
Locations: University of California, Los Angeles, Los Angeles, California
Conditions: Pain, Appetite Loss, Abuse, Drug
Motor Cortical Neuromodulation in Women With Interstitial Cystitis/Bladder Pain Syndrome
Recruiting
Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) is a common, chronic, and debilitating condition in women. Preliminary evidence suggests that IC/BPS pain can be reduced applying non-invasive repetitive transcranial magnetic stimulation (rTMS) to areas of the brain that regulate pelvic floor muscle activity. However, prior studies have examined rTMS in a very limited sample and have not examined changes in brain or pelvic floor muscle activity to determine the mechanism of rTMS for IC/BPS. T... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
03/11/2023
Locations: University of Southern California, Los Angeles, California
Conditions: Interstitial Cystitis, Bladder Pain Syndrome
The Effect of Zolpidem on Outcomes Following Lumbar Spine Fusion
Recruiting
The purpose of this study is to evaluate if peri-operative zolpidem for posterior lumbar spinal fusion improves patient reported outcomes following surgery.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
02/22/2023
Locations: Keck Medical Center of USC, Los Angeles, California
Conditions: Spine Fusion, Lumbar Spine Degeneration, Pain, Postoperative, Lumbar Spine Spondylosis
Percutaneous Electrical Nerve Field Stimulation for Adults With Irritable Bowel Syndrome
Recruiting
This is a prospective, double-blind, randomized, sham-controlled pilot study evaluating the efficacy of percutaneous electrical nerve field stimulation for the treatment of adult patients with irritable bowel syndrome (IBS).
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
01/09/2023
Locations: UCLA, Los Angeles, California
Conditions: Irritable Bowel Syndrome, Abdominal Pain, Autonomic Nervous System Imbalance
STIMFIX Trail Lead Anchor System for Dorsal Column Stimulator Trail Leads (SECURE Study)
Recruiting
This project will investigate the efficacy of a Stimfix Trail lead anchor system (StimfixTM) in patients undergoing dorsal column stimulator trial. In dorsal column stimulator trails, two leads are placed in the epidural space and various frequencies, pulse widths, and amplitudes are run to reduce pain perception. This therapy has been in use for the last 70 years and today there are about 100,000 implants done annually for various pain indications. The process of obtaining the therapy requires... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/07/2022
Locations: Nuvation Pain Group, Los Angeles, California
Conditions: Pain
Differential Target Multiplexed Spinal Cord Stimulation (DTM-SCS®) Real World Outcomes
Recruiting
The UPGRADE registry will capture long-term, real-world outcomes to understand the effect of Differential Target Multiplexed (DTM®) programming in the Spinal Cord Stimulation (SCS) implanted population on the management of chronic pain, primarily on its use for trunk and/or limb pain. The clinical study is sponsored by Celéri Health and is funded through a financial grant from Medtronic's External Research Program. The registry study will be conducted across approximately 25 centers in the Unite... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
09/28/2022
Locations: NuVation Pain Group - Los Angeles, Los Angeles, California
Conditions: Chronic Pain