There are currently 621 clinical trials in Sacramento, California looking for participants to engage in research studies. Trials are conducted at various facilities, including University of California Davis Comprehensive Cancer Center, University of California, Davis Medical Center, University of California, Davis and Sutter Medical Center Sacramento. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Testing the Effectiveness of an Anti-cancer Drug, Triapine, When Used With Targeted Radiation-based Treatment (Lutetium Lu 177 Dotatate), Compared to Lutetium Lu 177 Dotatate Alone for Metastatic Neuroendocrine Tumors
NCT05724108
Recruiting
This phase II trial compares the effect of adding triapine to lutetium Lu 177 dotatate versus lutetium Lu 177 dotatate alone (standard therapy) in shrinking tumors or slowing tumor growth in patients with neuroendocrine tumors that have spread from where they first started (primary site) to other places in the body (metastatic). Triapine may stop the growth of tumor cells by blocking some of the enzymes needed for deoxyribonucleic acid synthesis and cell growth. Lutetium Lu 177 dotatate is a rad... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/16/2024
Locations: University of California Davis Comprehensive Cancer Center, Sacramento, California
Conditions: Metastatic Neuroendocrine Tumor
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Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancer
NCT04812366
Recruiting
The objective of this study is to see if providing an appropriate therapy based on the genomic testing of prostate tumour tissue will result in an improved clinical response. Each participant will be treated with 8 weeks of a luteinizing hormone-releasing hormone agonist (LHRHa) plus apalutamide (APA) while genome sequence characterization is being done. Participants with biopsy specimens deemed unevaluable for genomic testing will remain on LHRHa plus APA for an additional 16 weeks. Participa... Read More
Gender:
Male
Ages:
18 years and above
Trial Updated:
05/16/2024
Locations: University of California Davis, Sacramento, California
Conditions: Prostate Cancer
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Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD
NCT04984226
Recruiting
Skeletal muscle metabolic health is critical for mobility and an underrecognized target of metabolic acidosis in chronic kidney disease. Impaired muscle mitochondrial metabolism underlies poor physical endurance increasing the risk of mobility disability. The proposed project will use precise in vivo tools to study the pathophysiology of poor physical endurance in a clinical trial treating metabolic acidosis among persons living with chronic kidney disease.
Gender:
All
Ages:
Between 21 years and 85 years
Trial Updated:
05/16/2024
Locations: University of California Davis Health, Sacramento, California
Conditions: Chronic Kidney Diseases, Metabolic Acidosis, Fatigue, Physical Endurance, Insulin Resistance, Mitochondrial Energetics, Diabetes
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Testing the Combination of Nivolumab and ASTX727 for Relapsed or Refractory B-Cell Lymphoma
NCT05272384
Recruiting
This phase I trial tests the safety, side effects, and best dose of nivolumab in combination with ASTX727 in treating B-cell lymphoma that has come back (relapsed) or does not respond to treatment (refractory). Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. ASTX727 consists of the combination of decitabine and cedazuridine. Cedazuridine is in a class of medicat... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/16/2024
Locations: University of California Davis Comprehensive Cancer Center, Sacramento, California
Conditions: Recurrent B-Cell Non-Hodgkin Lymphoma, Recurrent Diffuse Large B-Cell Lymphoma, Recurrent Hodgkin Lymphoma, Refractory B-Cell Non-Hodgkin Lymphoma, Refractory Diffuse Large B-Cell Lymphoma, Refractory Hodgkin Lymphoma
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Effects of Brain Stimulation on Higher-Order Cognition
NCT03814967
Recruiting
The purpose of this study is to better understand the neural correlates of higher-order cognition, both in the healthy brain and in schizophrenia, and to determine how these mechanisms are modulated by transcranial direct current stimulation (tDCS) at frontal and occipital scalp sites. Testing the effects of tDCS at these scalp sites on cognitive task performance will help us understand the roles of the brain regions corresponding to these sites during higher-order cognitive processing (language... Read More
Gender:
All
Ages:
Between 18 years and 50 years
Trial Updated:
05/15/2024
Locations: Imaging Research Center, Sacramento, California
Conditions: Schizophrenia
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De-Implementing Fall Prevention Alarms in Hospitals
NCT06089239
Recruiting
This is a Hybrid II de-implementation study to reduce use of fall prevention alarms in hospitals. The intervention consists of tailored, site-specific approaches for three core implementation strategies: education, audit/feedback and opinion leaders. Hospital units will be randomized to low-intensity or high-intensity coaching for the implementation of the tailored strategies.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/15/2024
Locations: University of California Davis Medical Center, Sacramento, California
Conditions: Accidental Fall, Patient Safety, Hospital Acquired Condition, Clinical Alarms, Mentoring
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Prospective Study of Nutraceutical Supplements to Support Hair Growth in Females
NCT06376409
Recruiting
A single site open label interventional study evaluating currently marketed hair supplements targeting the underlying root causes of thinning hair.
Gender:
Female
Ages:
Between 18 years and 70 years
Trial Updated:
05/15/2024
Locations: Integrative Skin Science and Research, Sacramento, California
Conditions: Hair Thinning
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Macronutrients in Lactating NICU Parents - Impact of Kangaroo Care
NCT06047470
Recruiting
The goal of this clinical trial is to learn about the impact of Kangaroo Care (holding your baby skin-to-skin on your chest) in lactating parents with babies in the Neonatal Intensive Care Unit (NICU) that cannot directly breastfeed.
Gender:
Female
Ages:
Between 18 years and 100 years
Trial Updated:
05/15/2024
Locations: UC Davis, Sacramento, California
Conditions: Lactation Disorder With Baby Delivered, Nutrition Disorder, Infant
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Utilization of Negative Pressure Suction to Reduce Aspiration in Oropharyngeal Dysphagia
NCT03368079
Recruiting
This is an investigator initiated prospective study to determine whether the use of a negative pressure suction in the hypopharynx will reduce the amount of aspiration during Video Fluoroscopic Swallowing Exam (VFSE) among patients with oropharyngeal dysphagia.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/14/2024
Locations: UC Davis Medical Center, Sacramento, California
Conditions: Oropharyngeal Dysphagia
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Pulmonary Hypertension Association Registry
NCT04071327
Recruiting
The PHA Registry (PHAR) is a national study about people who have pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). PHAR collects information from people with PAH and CTEPH who are cared for in participating PHA-accredited Pulmonary Hypertension Care Centers throughout the U.S. PHAR will determine how people with PAH and CTEPH are evaluated, tested, and treated, and will observe how well these participants do. The goal is to see if people with PH a... Read More
Gender:
All
Ages:
0 years and above
Trial Updated:
05/14/2024
Locations: UC Davis Health, Sacramento, California
Conditions: Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension, Pulmonary Hypertension
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Tumescence in HNC Skin Graft Reconstruction
NCT04967391
Recruiting
Our primary objective is to determine if the use of tumescence has a meaningful effect on STSG uptake at the recipient site. This is an important outcome because poor graft uptake results in the need for prolonged local wound care, additional clinic visits for patients and increased risk of infection. A prospective, randomized comparison of the tumescence to our current standard of care will allow us to definitively evaluate any benefits to this technique. Tumescence is commonly used in the tre... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/14/2024
Locations: UC Davis Health, Sacramento, California
Conditions: Head and Neck Cancer, Surgery--Complications, Graft Failure
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A Study About How Well TAK-279 Works and Its Safety in Participants With Moderate-to-severe Plaque Psoriasis During 52 Weeks of Treatment
NCT06088043
Recruiting
The main aim of this study is to show how well TAK-279 reduces the skin plaques compared to placebo, in participants with moderate-to-severe plaque psoriasis. Participants will be assigned to one of the 3 study treatments (TAK-279, apremilast (an approved treatment), or a placebo). Participants will be in the study for up to 56 weeks.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/14/2024
Locations: UC Davis Dermatology Clinic, Sacramento, California
Conditions: Plaque Psoriasis
Register for Updates